Attendees

• Eric, TomG, Elaine, Greg, Scooter, TomF

Agenda

• Nail down firm ChimeraX 1.2 release date
  • Needed for R01 RPPR annual report
• Funding Update:
  • DoD ACSR cryoEM proposal due to Stanford C&G by May 7th - TEF
  • CZI Essential Software proposal, due May 19 - Scooter
    • avoid any changes to license at this point; tell CZI our license is type "other"
  • R01 renewal, due July 5, 2021
    • draft research plan is in Google Docs
    • Specific Aims to be enumerated after Research Plan is more developed
    • discuss status and writing assignments - All
  • NTT Data - ​task order
    • does the contract need to be modified given the Adams R24 OS that was submitted to NIH?
  • Adelson grant status report - Scooter
• New hire job ​description
  • Status of job listing - Scooter
  • How to get the word out: Twitter, Chimera/X mailing lists, registered Chimera users list, other? - All
  • Do we want a more detailed document for use in targeted advertising instead of the restrictive one required by UCSF HR? - All
  • Someone needs to take the lead on widely posting this job opening - Eric/Elaine?
  • Should Greg increase his level of effort for the RBVI? - Greg
    • Pro: plenty of ChimeraX work to do
    • Con: may burn intra-departmental bridges with other PIs and eliminate future support opportunities if funding pressures occurs in the future (i.e., fewer eggs in the basket)
• SPOKE:
  • Status report - Scooter
  • Do we need to re-consider our level of involvement in this project?
    • what are the scientific benefits? - Scooter
    • what level of funding do we receive? - Scooter
    • what is the level of enthusiasm of RBVI staff? - All
    • does this project leverage our expertise? - All
• Review Action Items list below - TomG

Discussion Notes

• New hire
  • New hire job description submitted -- waiting for them to put it up.
  • How to advertise, twitter, mailing list.
  • TomG will write word-cloud few sentences and pass text around -- post when job listed on brassring.com.

• Can Greg work more on ChimeraX
  • Says he can only get a little time back unless he drops some PI.
  • (Jacobson 12.5%, NMR 12.5%, Wynton 25%, RBVI 50%)
  • Can he drop NMR? Would leave them in bad position.

• Wynton will be down 1 full day and all CGL servers/email/plato for power work.

• CZI essential software.
  • License will say "other". Could mention releasing PyPi package of core capabilities.
  • Scooter will engage contacts and grants, and work on budget.
  • TomG will make google doc for full proposal so everyone can expand details.

• Wah Chiu DoD cryoEM proposal
  • Proposal due May 7, 15 pages, we were on sent in letter of intent
  • We might provide 2 pages on visualization that factors into most of their projects.
  • TomG can talk to Mike Schmid about contributing that.
  • Need nsf biosketches for TomF, TomG. Ask Mike if they will need TomG biosketch, if so get form from TomG.
  • Work on DoD proposal before CZI.

• AI structure prediction
  • AlphaFold2 - google, controversial
  • Should talk to Tanya Kortemme for R01

• ChimeraX 1.2 release date -- send email when it is determined.

• Replace Opal with REST - Scooter and Eric

Action Items

• Create tutorial for putting model on web page - TomG
• Summarize Phenix R24 ChimeraX aims to avoid conflict with R01 proposal - TomG
• Buy Mac Mini with Apple Silicon and KVM switch - TomG
• Figure out what additional plato directories need backup - Scooter
• Set up 2-factor authentication for hal2 vpn - Scooter
• Document new vpn setup on Linux - Scooter