Attendees

• Zach, Eric, Elaine, Greg, TomG, Scooter, TomF

Agenda

• Review summary statement for R01 grant, Google doc (link sent by email)
• ChimeraX 1.3 release progress.
• Create ChimeraX 1.4 roadmap
• New desktop computer hardware.
• Review Action Items list below

Discussion Notes

• Wynton bgfs file system problems
  • Plato not responding right now, Trac not accessible.
  • Wynton admins working on it, recovered part way through this meeting.

• R01 grant resubmission
  • Resubmission due date is March 5, 2021.
  • Even if our current R01 gets funding (1/3 chance?) it would likely have budget cut in half. So we still want to resubmit to hopefully get full budget.
  • Resubmission will be to Macromolecular Structure and Function C panel since MSFD is being disbanded at end of this year.
  • Scooter made copy of R01 proposal google doc.
  • First step is to mark parts of current proposal that need revision or addition, and mark parts that are strong and should be kept.
  • We are exactly at 12 page limit, so any addition must be balanced by deletion.
  • We are allowed 1 extra page for resubmission to explain how we addressed preview critique.

• R01 grant addressing reviewer critique
  • Discussed 8 points in TomG's Google Doc summary of our R01 review.
  • Add AlphaFold and possibly RoseTTAFold preliminary progress and plans.
  • Might consider asking for hardware for alphafold server.
  • Reduce local interactive MD discussion, focus on MD need for cryoEM / ISOLDE
  • Need to think how to do plugin quality control without taking lots of our time.
    • Cytoscape does not have quality filtering for submitted plugins
  • More fine-grain estimates of effort for tasks might help address comment that 2 programmers should be eliminated. This is critical.

Action Items

• Setup meeting with NIH R01 program officer to discuss resubmission, Tom Ferrin
• Get certificate for https at rbvi.org. Greg
• Renew certificate for https on vr.ucsf.edu. Greg
• Set up 2-factor authentication for hal2 vpn - (waiting to see if VPN will even be allowed by campus IT) - Scooter
• Document new vpn setup on Linux - Scooter