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The RAD52 double-ring remodels replication forks restricting fork reversal. Honda M, Razzaghi M et al. Nature. 2025 May 8;641(8062):512–519.
Snapshots of acyl carrier protein shuttling in human fatty acid synthase. Schultz K, Costa-Pinheiro P et al. Nature. 2025 May 8;641(8062):520–528.
Structural dynamics of human fatty acid synthase in the condensing cycle. Choi W, Li C et al. Nature. 2025 May 8;641(8062):529–536.
Structural dynamics of DNA unwinding by a replicative helicase. Shahid T, Danazumi AU et al. Nature. 2025 May 1;641(8061):240–249.
Cryo-EM reveals mechanisms of natural RNA multivalency. Wang L, Xie J et al. Science. 2025 May 1;388(6746):545-550.
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May 7, 2025
The ChimeraX 1.10 release candidate is available – please try it and report any issues. See the change log for what's new.
March 19, 2025
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March 1, 2025
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UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see ChimeraX commercial licensing.
ChimeraX is developed with support from National Institutes of Health R01-GM129325.
Feature Highlight
Different representations of nucleotides can be shown with the
nucleotides
command or Toolbar
icons. Options include filled rings, slabs for bases
(box, muffler, or ellipsoid shape), bumps on slabs to show base orientation,
simple tubes instead of ribose atoms, and continuous or broken ladder rungs.
Nucleotide representations can be the same color as the ribbon
or a different color, and multiple nucleotide styles can be used
within a single structure.
See also: Presets menu
Example Image
Influenza neuraminidase is an enzyme that promotes the spread of influenza
virus among host cells.
It is the target of oseltamivir and related antiviral drugs.
The image shows tetramers of neuraminidase (PDB
3k3a) styled as flowers. Three tetramers are in different
shades of pink, with a central metal ion in white and nearby residues in yellow,
and a fourth tetramer is colored green to resemble leaves.
Each monomer or “petal” is a six-bladed β-propeller.
For image setup other than orientation,
see the command file flowers.cxc.
The Chimera Image Gallery includes a similar image.
Stylized Nucleotides
Neuraminidase Flowers
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