Convolutional neural networks for automated annotation of cellular cryo-electron tomograms. Chen M, Dai W et al. Nat Methods. 2017 Oct;14(10):983-985.
PDB-Dev: A prototype system for depositing integrative/hybrid structural models. Burley SK, Kurisu G et al. Structure. 2017 Sep 5;25(9):1317-1318.
Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase. Verba KA, Wang RY et al. Science. 2016 Jun 24;352(6293):1542-7.
Structure and membrane remodeling activity of ESCRT-III helical polymers. McCullough J, Clippinger AK et al. Science. 2015 Dec 18;350(6267):1548-51.See also RCSB PDB images...
October 3, 2017
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Our ChimeraX paper is accessible online! UCSF ChimeraX: Meeting modern challenges in visualization and analysis. Goddard TD, Huang CC et al.. Protein Sci. 2017, in press.
UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see licensing.
ChimeraX development is funded by the National Institutes of Health (NIGMS P41-GM103311).
Morphing between atomic structures can be calculated wih the morph command and played back in an animation. This movie shows morphing between two conformations of the FGFR1 kinase domain:
Morphing and other setup was done with the command file kmorph-prep.cxc, followed by interactively positioning the structure and saving the view, then running kmorph-play.cxc to add 2D labels and record the movie.More features...
The GDP- and GTP-bound conformations of the transducin α-subunit (1tag and 1tnd, respectively) differ primarily in three regions, termed switch 1, switch 2, and switch 3. The structures have been superimposed with matchmaker and shown as cartoons, with “empty” outlines where the structures are almost the same (for simplicity, only one conformation's outlines are shown). The GTP analog GTPγS is displayed as spheres color-coded by heteroatom. For 2D labels and image setup other than structure orientation, see the command file switch.cxc.