Attendees

Elaine, Greg, TomF, TomG, Conrad, Scooter

Agenda

• Review action items from last meeting
• Chimera 1.11 Release
• Windows ChimeraX builds
• PyQt status
  • nuke wx?
  • License text/file in source files
• Next steps for ChimeraX

Discussion

• Previous action items:
  • Eric created scheme ticket
  • OU can be included in certificate
  • UCSF does not have EV cert yet, but does not matter
    • Must have local cert to sign app
• Chimera 1.11 Release
  • Wait another week before finalizing
• Windows ChimeraX builds
  • Daily build not working for Windows but manual build works
  • We can start distributing Qt version after we get license text in place
  • We cannot nuke wx until Qt version is available
  • Need download web interface that asks for agreement to license
  • Two queries to Riverbank
    • Fix file paths in PyQt5 pypi and commercial wheels
    • Build commercial wheel using custom Qt
• Next steps for ChimeraX
  • Site visit demo scenarios
    • "Scenarios" seem to work well
    • IHM nuclear pore data
    • CRISPR (EM, multiple contact map, etc)?
    • Cell motility?
    • RINs/chain contacts for Cytoscape+ChimeraX?
    • Zika virus?
    • Graham's new stuff?
    • May depend on committee members
  • Things that we really want to show
    • 3A cryo-EM (residue-fit viewer, connection to 2D)
    • New lighting models
    • Cytoscape interface
      • REST interface
    • Toolshed
    • New UI
      • HTML help and log
      • Quick start guide
    • Ribbons with secondary structure smoothing
    • Large data sets (open/display)
    • mmCIF support (PDB/IHM)
    • 3D-2D links to fancy plots (one of...)
      • chain contact graph
      • hierarchy explorer
      • cross-link distribution histograms
      • domains from web service
    • Web services (one of...)
      • Domains (most striking) with 2D diagram/graph
      • Blastpdb
      • PDB2PQR/APBS
    • IHM mmCIF support
      • Hierarchy explorer
      • Low-res representations (beads)
      • Cross link viewing
  • Things we like to show (if available)
    • String database
    • Hydrogen bonds and contacts
    • MAV/conservation/contacts
      • Multiple sequence alignment
      • Homology modeling services
    • Link to high-performance web viewing
    • MLP
    • Light microscopy
    • Molprobity
    • Virtual reality interface (Vive)
  • Release features

Outstanding Action Items

• TomF will get answers for ChimeraX license
• Eric will create ticket for converting from cxcmd: to http: scheme in web viewer
• Greg will find out whether we can get code signing certificate with our unit name in it
• Greg will find out from IT whether they are willing to sign ChimeraX with their new EV cert
• Conrad will download IHM data to plato and send mail