Opened 9 months ago

#16715 assigned enhancement

Add species name filter for similar structures and BLAST searches

Reported by: matthias.vorlaender@… Owned by: Tom Goddard
Priority: moderate Milestone:
Component: Sequence Version:
Keywords: Cc: Zach Pearson
Blocked By: Blocking:
Notify when closed: Platform: all
Project: ChimeraX

Description

Matthias Vorlander asked for limiting BLAST search to a specified species to limit results from the alphafold database.

https://mail.cgl.ucsf.edu/mailman/archives/list/chimerax-users@cgl.ucsf.edu/thread/ZYUT7O4BPWKGJJXBZHOHHJSDOKOCHTGS/

This could be done for the blastprotein command and the similar structures search commands. Probably want to just match the species prefix since often strain is included in the species name. Also probably should be case insensitive.

From: Vorländer,Matthias Kopano
Subject: [chimerax-users] Limit blast search to species
Date: January 27, 2025 at 11:12:34 PM PST
To: "ChimeraX-users@…" <chimerax-users@…>

Dear ChimeraX team,

I wondered if it is possible to limit a BLAST search to only a single species when querying a selected database. This would facilitate identifying homologs in your favorite model organism, rather than picking up the most closely related homolog overall (i.e when using the alphafold database).

Many thanks,
Matthias

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