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A high-throughput selection system for fast-acting covalent protein drugs. Fan Q, Mei J et al. Science. 2026 May 28;392(6801):eadv3081.
Architecture of clathrin-independent AP3:ARF1-coated carriers. Kaufman JGG, Tagiltsev G et al. Sci Adv. 2026 May 15;12(20):eaed1529.
Open and closed forms of assembled henipavirus nucleoprotein suggest structural basis of genome access. Jayachandran RB, Quignon E, Renner M. Sci Adv. 2026 May 15;12(20):eaed8300.
The molecular basis of force selectivity by PIEZO2. Mulhall EM, Yarishkin O et al. Nature. 2026 May 7;653(8113):297–305.
Human DHX29 detects nonoptimal codon usage to regulate mRNA stability. Hia F, Wu Y et al. Science. 2026 May 7;392(6798):eadw0288.
Previously featured citations...Chimera Search
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December 25, 2025
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September 22, 2025
Mac users may wish to defer upgrading to MacOS Tahoe. Currently on that OS the Chimera graphics window is shifted so that it covers the command and status lines.
March 6, 2025
Chimera production release 1.19 is now available, fixing the ability to fetch structures from the PDB (1.19 release notes).
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UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.
We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features in addition to nearly all the capabilities of Chimera (details...).
Chimera is no longer under active development. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.
Feature Highlight
Gallery Sample
The image shows the structure of the human TRPA1 ion channel (wasabi receptor) determined by electron cryo-microscopy, Protein Data Bank entry 3j9p. The four subunits of the tetramer are shown as ribbons in different colors over a dark-to-light gradient background. (More samples...)
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