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Recent Citations

Regulation of STING activation by phosphoinositide and cholesterol. Li J, Tan JX et al. Nature. 2026 Apr 9;652(8109):499–507.

eT 2.0: An efficient open-source molecular electronic structure program. Folkestad SD, Kjønstad EF et al. J Chem Phys. 2026 Apr 7;164(13):132501.

The Erlin1/2 complex is a dynamic scaffold for membrane microdomain assembly on the endoplasmic reticulum. Yan L, Xu Z et al. Mol Cell. 2026 Apr 2;86(7):1362-1376.e5.

Microtubules guide Aurora B substrate geometries for accurate chromosome segregation. Niu Y, DeLuca KF et al. Sci Adv. 2026 Mar 27;12(13):eaea2112.

Discovery and cryoEM structure of FPM13, a periplasmic metalloprotein unique to Francisella. Clemens DL, Lee BY et al. PLoS Pathog. 2026 Mar 27;22(3):e1014024.

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News

December 25, 2025

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The RBVI wishes you a safe and happy holiday season! See our 2025 card and the gallery of previous cards back to 1985.

September 22, 2025

Mac users may wish to defer upgrading to MacOS Tahoe. Currently on that OS the Chimera graphics window is shifted so that it covers the command and status lines.

March 6, 2025

Chimera production release 1.19 is now available, fixing the ability to fetch structures from the PDB (1.19 release notes).

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Please note that UCSF Chimera is legacy software that is no longer being developed or supported. Users are strongly encouraged to try UCSF ChimeraX, which is under active development.
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UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.

We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features in addition to nearly all the capabilities of Chimera (details...).

Chimera is no longer under active development. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.

Feature Highlight

coloring by bfactor

B-Factor Coloring

A structure can be colored to show values of an attribute such as atomic B-factor. The image includes a molecular surface that has been clipped and capped, 2D labels, and a color key. Color Zone was used to color the planar cross-section of the surface (see image how-to).

(More features...)

Gallery Sample

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Loop Interactions

The image shows interactions of the delta-1 loop with the rest of hepatitis C virus RNA-dependent RNA polymerase (Protein Data Bank entry 1quv). Loop residues in contact with the rest of the structure (van der Waals overlap ≥ 0.01 Å) are displayed as sticks; interacting surface atoms are shown as red patches. (More samples...)


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