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Recent Citations

Psychedelics elicit their effects by 5-HT(2A) receptor-mediated G(i) signalling. Xu Z, Wang H et al. Nature. 2026 Mar 19;651(8106):829–837.

Polymerase trapping as the mechanism of H5 highly pathogenic avian influenza virus genesis. Funk M, Spronken MI et al. Science. 2026 Mar 12;391(6790):eadr6632.

Identification of an allosteric site on the E3 ligase adapter cereblon. Dippon VN, Rizvi Z et al. Nature. 2026 Mar 12;651(8105):482-490.

Structural remodeling of the mitochondrial protein biogenesis machinery under proteostatic stress. Ehses K, López-Alonso JP et al. Sci Adv. 2026 Mar 6;12(10):eaed3579.

Structures of Ostα/β reveal a unique fold and bile acid transport mechanism. Yang X, Cui N et al. Nature. 2026 Mar 5;651(8104):260–267.

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News

December 25, 2025

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The RBVI wishes you a safe and happy holiday season! See our 2025 card and the gallery of previous cards back to 1985.

September 22, 2025

Mac users may wish to defer upgrading to MacOS Tahoe. Currently on that OS the Chimera graphics window is shifted so that it covers the command and status lines.

March 6, 2025

Chimera production release 1.19 is now available, fixing the ability to fetch structures from the PDB (1.19 release notes).

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Please note that UCSF Chimera is legacy software that is no longer being developed or supported. Users are strongly encouraged to try UCSF ChimeraX, which is under active development.
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UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.

We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features in addition to nearly all the capabilities of Chimera (details...).

Chimera is no longer under active development. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.

Feature Highlight

surface color by density

Coloring by Density

A surface can be colored by density or other volume data. In the image, the surface is clipped and capped, and only the cap is colored by density. Different coloring schemes can be applied.

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Gallery Sample

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Wasabi Receptor

The image shows the structure of the human TRPA1 ion channel (wasabi receptor) determined by electron cryo-microscopy, Protein Data Bank entry 3j9p. The four subunits of the tetramer are shown as ribbons in different colors over a dark-to-light gradient background. (More samples...)


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