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Pre-incision structures reveal principles of DNA nucleotide excision repair. Li ECL, Kim J et al. Nature. 2026 Apr 23;652(8111):1060–1067.
Regulation of STING activation by phosphoinositide and cholesterol. Li J, Tan JX et al. Nature. 2026 Apr 9;652(8109):499–507.
eT 2.0: An efficient open-source molecular electronic structure program. Folkestad SD, Kjønstad EF et al. J Chem Phys. 2026 Apr 7;164(13):132501.
The Erlin1/2 complex is a dynamic scaffold for membrane microdomain assembly on the endoplasmic reticulum. Yan L, Xu Z et al. Mol Cell. 2026 Apr 2;86(7):1362-1376.e5.
Microtubules guide Aurora B substrate geometries for accurate chromosome segregation. Niu Y, DeLuca KF et al. Sci Adv. 2026 Mar 27;12(13):eaea2112.
Previously featured citations...Chimera Search
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December 25, 2025
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September 22, 2025
Mac users may wish to defer upgrading to MacOS Tahoe. Currently on that OS the Chimera graphics window is shifted so that it covers the command and status lines.
March 6, 2025
Chimera production release 1.19 is now available, fixing the ability to fetch structures from the PDB (1.19 release notes).
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UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.
We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features in addition to nearly all the capabilities of Chimera (details...).
Chimera is no longer under active development. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.
Feature Highlight
The fly command can animate a flight through molecular structures. Click the example image to fly along the RNA being copied by rotavirus RNA polymerase (PDB 2r7r), an enzyme that replicates the 11 segments of viral RNA.
(More features...)
Gallery Sample
The image shows the structure of the human TRPA1 ion channel (wasabi receptor) determined by electron cryo-microscopy, Protein Data Bank entry 3j9p. The four subunits of the tetramer are shown as ribbons in different colors over a dark-to-light gradient background. (More samples...)
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