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Featured Citations

Structure of nucleosome-bound human BAF complex. He S, Wu Z et al. Science. 2020 Feb 21;367(6480):875-881.

Constructing protein polyhedra via orthogonal chemical interactions. Golub E, Subramanian RH et al. Nature. 2020 Feb 6;578(7793):172-176.

Structure of the Bcs1 AAA-ATPase suggests an airlock-like translocation mechanism for folded proteins. Kater L, Wagener N et al. Nat Struct Mol Biol. 2020 Feb;27(2):142-149.

Structure of SAGA and mechanism of TBP deposition on gene promoters. Papai G, Frechard A et al. Nature. 2020 Jan 30;577(7792):711-716.

The inner junction complex of the cilia is an interaction hub that involves tubulin post-translational modifications. Khalifa AAZ, Ichikawa M et al. eLife. 2020 Jan 17;9. pii: e52760.

See also: RCSB PDB Images
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December 23, 2019

The ChimeraX 0.91 production release is available. See the change log for what's new.

October 16, 2019

ChimeraX virtual reality featured in UCSF School of Pharmacy news: VR Drug Discovery Makes Precision Therapy a Reality  [video]

June 20, 2019

ChimeraX virtual reality shown on PBS Newshour: How Close are Scientists to a Universal Flu Vaccine?

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UCSF ChimeraX

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see licensing.

ChimeraX is developed with support from National Institutes of Health R01-GM129325 and the Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases.

Feature Highlight

DNA/protein complex with struts

Struts for 3D Printing

Structures can be reinforced for 3D printing with pseudobonds. In this DNA-transcription factor complex (PDB 5ego), proteins are shown as ribbons and the DNA as a molecular surface. The pseudobonds in blue were read in from a manually created file, 5ego.pb, and further reinforcements in light gray were added automatically with the struts command. For image setup other than orientation, see the command file struts.cxc.

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Example Image

photosynthetic reaction center

Photosynthetic Reaction Center

The photosynthetic reaction center from a purple sulfur bacterium is shown as a cartoon with “tube” helices and membrane boundaries from the OPM database (Orientations of Proteins in Membranes, entry 1eys). Blue and red balls represent the cytoplasmic and periplasmic sides of the bacterial inner membrane, respectively. The title and other text labels were added with the 2dlabels command and repositioned interactively with the move label mouse mode . ChimeraX session file: prc.cxs

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