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Citations (partial list)

Breaking the law: unconventional strategies for antibody diversification. Kanyavuz A, Marey-Jarossay A et al. Nat Rev Immunol. 2019 Jun;19(6):355-368.

Structural dynamics of bacteriophage P22 infection initiation revealed by cryo-electron tomography. Wang C, Tu J et al. Nat Microbiol. 2019 Jun;4(6):1049-1056.

The structure of the stress-induced photosystem I-IsiA antenna supercomplex. Toporik H, Li J et al. Nat Struct Mol Biol. 2019 Jun;26(6):443-449.

In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release. Ding K, Celma CC et al. Nat Commun. 2019 May 17;10(1):2216.

An ultra-stable gold-coordinated protein cage displaying reversible assembly. Malay AD, Miyazaki N et al. Nature. 2019 May 16;569(7756):438-442.

Predicting protein dimer structures using MELD × MD. Brini E, Kozakov D, Dill KA. J Chem Theory Comput. 2019 May 14;15(5):3381-3389.

Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses. Dodonova SO, Prinz S et al. Proc Natl Acad Sci USA. 2019 May 14;116(20):10048-10057.

Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes. Maeda S, Qu Q et al. Science. 2019 May 10;364(6440):552-557.

Visualization of clustered protocadherin neuronal self-recognition complexes. Brasch J, Goodman KM et al. Nature. 2019 May 9;569(7755):280-283.

Three-dimensional architecture of epithelial primary cilia. Sun S, Fisher RL et al. Proc Natl Acad Sci USA. 2019 May 7;116(19):9370-9379.

A compact synthetic pathway rewires cancer signaling to therapeutic effector release. Chung HK, Zou X et al. Science. 2019 May 3;364(6439). pii: eaat6982.

Integrating Hi-C and FISH data for modeling of the 3D organization of chromosomes. Abbas A, He X et al. Nat Commun. 2019 May 3;10(1):2049.

eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response. Kenner LR, Anand AA et al. Science. 2019 May 3;364(6439):491-495.

Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport. Coleman JA, Yang D et al. Nature. 2019 May 2;569(7754):141-145.

Designing a chemical inhibitor for the AAA protein spastin using active site mutations. Cupido T, Pisa R et al. Nat Chem Biol. 2019 May;15(5):444-452.

Atomic structure of the translation regulatory protein NS1 of bluetongue virus. Kerviel A, Ge P et al. Nat Microbiol. 2019 May;4(5):837-845.

Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP γ8. Herguedas B, Watson JF et al. Science. 2019 Apr 26;364(6438):eaav9011.

Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM. Zhao Y, Chen S et al. Science. 2019 Apr 26;364(6438):eaaw8250.

An allosteric mechanism for potent inhibition of human ATP-citrate lyase. Wei J, Leit S et al. Nature. 2019 Apr 25;568(7753):566-570.

Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM. Righetto RD, Biyani N et al. Nat Commun. 2019 Apr 12;10(1):1722.

Structure and dynamics of the active human parathyroid hormone receptor-1. Zhao LH, Ma S et al. Science. 2019 Apr 12;364(6436):148-153.

Ligand-triggered allosteric ADP release primes a plant NLR complex. Wang J, Wang J et al. Science. 2019 Apr 5;364(6435). pii: eaav5868.

The phage L capsid decoration protein has a novel OB-fold and an unusual capsid binding strategy. Newcomer RL, Schrad JR et al. eLife. 2019 Apr 4;8. pii: e45345.

De novo structural pattern mining in cellular electron cryotomograms. Xu M, Singla J et al. Structure. 2019 Apr 2;27(4):679-691.e14.

Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry. Guo M, Zhang K et al. Cell Res. 2019 Apr;29(4):305-312.

Structural basis of lipopolysaccharide extraction by the LptB2FGC complex. Li Y, Orlando BJ, Liao M. Nature. 2019 Mar 28;567(7749):486-490.

3D printed absorber for capturing chemotherapy drugs before they spread through the body. Oh HJ, Aboian MS et al. ACS Cent Sci. 2019 Mar 27;5(3):419-427.

Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins. Shen H, Liu D et al. Science. 2019 Mar 22;363(6433):1303-1308.

Mechanism of DNA translocation underlying chromatin remodelling by Snf2. Li M, Xia X et al. Nature. 2019 Mar 21;567(7748):409-413.

Structural basis of STING binding with and phosphorylation by TBK1. Zhang C, Shang G et al. Nature. 2019 Mar 21;567(7748):394-398.

Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis. Radamaker L, Lin YH et al. Nat Commun. 2019 Mar 20;10(1):1103.

Ligand entry in human ileal bile acid-binding protein is mediated by histidine protonation. Horváth G, Egyed O et al. Sci Rep. 2019 Mar 18;9(1):4825.

Global computational mutagenesis of domain structures associated with inherited eye disease. Ortiz FW, Sergeev YV. Sci Rep. 2019 Mar 6;9(1):3676.

Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides. Chou SZ, Pollard TD. Proc Natl Acad Sci USA. 2019 Mar 5;116(10):4265-4274.

Cryo-EM of retinoschisin branched networks suggests an intercellular adhesive scaffold in the retina. Heymann JB, Vijayasarathy C et al. J Cell Biol. 2019 Mar 4;218(3):1027-1038.

Assessing the predictive power of relative binding free energy calculations for test cases involving displacement of binding site water molecules. Wahl J, Smieško M. J Chem Inf Model. 2019 Feb 25;59(2):754-765.

Circadian oscillator proteins across the kingdoms of life: structural aspects. Saini R, Jaskolski M, Davis SJ. BMC Biol. 2019 Feb 18;17(1):13.

CasX enzymes comprise a distinct family of RNA-guided genome editors. Liu JJ, Orlova N et al. Nature. 2019 Feb 14;566(7743):218-223.

Structural basis for recognition of ubiquitylated nucleosome by Dot1L methyltransferase. Anderson CJ, Baird MR et al. Cell Rep. 2019 Feb 12;26(7):1681-1690.e5.

Electron cryo-tomography provides insight into procentriole architecture and assembly mechanism. Li S, Fernandez JJ et al. eLife. 2019 Feb 11;8. pii: e43434.

Chemoinformatics and structural bioinformatics in OCaml. Berenger F, Zhang KYJ, Yamanishi Y. J Cheminform. 2019 Feb 5;11(1):10.

A multi-model approach to assessing local and global cryo-EM map quality. Herzik MA Jr, Fraser JS, Lander GC. Structure. 2019 Feb 5;27(2):344-358.e3.

Noncompetitive antagonists induce cooperative AMPA receptor channel gating. Shi EY, Yuan CL et al. J Gen Physiol. 2019 Feb 4;151(2):156-173.

The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography. Delavoie F, Soldan V et al. Nat Commun. 2019 Jan 30;10(1):497.

FGF21 trafficking in intact human cells revealed by cryo-electron tomography with gold nanoparticles. Azubel M, Carter SD et al. eLife. 2019 Jan 28;8. pii: e43146.

Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus. Whitesell L, Robbins N et al. Nat Commun. 2019 Jan 24;10(1):402.

GABAA receptor signalling mechanisms revealed by structural pharmacology. Masiulis S, Desai R et al. Nature. 2019 Jan 24;565(7740):454-459.

Chemical cross-linking enables drafting ClpXP proximity maps and taking snapshots of in situ interaction networks. Fux A, Korotkov VS et al. Cell Chem Biol. 2019 Jan 17;26(1):48-59.e7.

Domain insertion permissibility-guided engineering of allostery in ion channels. Coyote-Maestas W, He Y et al. Nat Commun. 2019 Jan 17;10(1):290.

Structure of the SLy1 SAM homodimer reveals a new interface for SAM domain self-association. Kukuk L, Dingley AJ et al. Sci Rep. 2019 Jan 10;9(1):54.

Structure of the posttranslational Sec protein-translocation channel complex from yeast. Itskanov S, Park E. Science. 2019 Jan 4;363(6422):84-87.

Structures of TRPV2 in distinct conformations provide insight into role of the pore turret. Dosey TL, Wang Z et al. Nat Struct Mol Biol. 2019 Jan;26(1):40-49.

Polarized displacement by transcription activator-like effectors for regulatory circuits. Lebar T, Verbič A et al. Nat Chem Biol. 2019 Jan;15(1):80-87.

Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Patel AB, Louder RK et al. Science. 2018 Dec 21;362(6421). pii: eaau8872.

Structure of native lens connexin 46/50 intercellular channels by cryo-EM. Myers JB, Haddad BG et al. Nature. 2018 Dec 20;564(7736):372-377.

Does ionic screening lower activation barriers for conformational transitions in proteins? Antosiewicz JM, Długosz M. J Phys Chem B. 2018 Dec 20;122(50):11817-11826.

CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers. Menny A, Serna M et al. Nat Commun. 2018 Dec 14;9(1):5316.

Structure and architecture of immature and mature murine leukemia virus capsids. Qu K, Glass B et al. Proc Natl Acad Sci USA. 2018 Dec 11;115(50):E11751-E11760.

SETD3 protein is the actin-specific histidine N-methyltransferase. Kwiatkowski S, Seliga AK et al. eLife. 2018 Dec 11;7. pii: e37921.

The evolution of ependymin-related proteins. McDougall C, Hammond MJ et al. BMC Evol Biol. 2018 Dec 4;18(1):182.

An electron transfer path connects subunits of a mycobacterial respiratory supercomplex. Gong H, Li J et al. Science. 2018 Nov 30;362(6418). pii: eaat8923.

Binding of histamine to the H1 receptor – a molecular dynamics study. Söldner CA, Horn AHC, Sticht H. J Mol Model. 2018 Nov 29;24(12):346.

Folding pathway of an Ig domain is conserved on and off the ribosome. Tian P, Steward A et al. Proc Natl Acad Sci USA. 2018 Nov 27;115(48):E11284-E11293.

Tracing whale myoglobin evolution by resurrecting ancient proteins. Isogai Y, Imamura H et al. Sci Rep. 2018 Nov 15;8(1):16883.

Conformational transitions of the serotonin 5-HT3 receptor. Polovinkin L, Hassaine G et al. Nature. 2018 Nov 8;563(7730):275-279.

Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core. Borst AJ, Weidle CE et al. eLife. 2018 Nov 7;7. pii: e37688.

Molecular structure of promoter-bound yeast TFIID. Kolesnikova O, Ben-Shem A et al. Nat Commun. 2018 Nov 7;9(1):4666.

Flaviviruses have imperfect icosahedral symmetry. Therkelsen MD, Klose T et al. Proc Natl Acad Sci USA. 2018 Nov 6;115(45):11608-11612.

Structural basis of the nucleosome transition during RNA polymerase II passage. Kujirai T, Ehara H et al. Science. 2018 Nov 2;362(6414):595-598.

Cross-linked peptide identification: A computational forest of algorithms. Yılmaz Ş, Shiferaw GA et al. Mass Spectrom Rev. 2018 Nov;37(6):738-749.

Conformational flexibility of pore loop-1 gives insights into substrate translocation by the AAA+ protease FtsH. Uthoff M, Baumann U. J Struct Biol. 2018 Nov;204(2):199-206.

Hierarchical organization endows the kinase domain with regulatory plasticity. Creixell P, Pandey JP et al. Cell Syst. 2018 Oct 24;7(4):371-383.e4.

The structure and dynamics of C. elegans tubulin reveals the mechanistic basis of microtubule growth. Chaaban S, Jariwala S et al. Dev Cell. 2018 Oct 22;47(2):191-204.e8.

Structural basis for the modulation of voltage-gated sodium channels by animal toxins. Shen H, Li Z et al. Science. 2018 Oct 19;362(6412). pii: eaau2596.

Structure and dynamics of the yeast SWR1-nucleosome complex. Willhoft O, Ghoneim M et al. Science. 2018 Oct 12;362(6411). pii: eaat7716.

A viral protein restricts Drosophila RNAi immunity by regulating Argonaute activity and stability. Nayak A, Kim DY et al. Cell Host Microbe. 2018 Oct 10;24(4):542-557.e9.

High-resolution structures of HIV-1 Gag cleavage mutants determine structural switch for virus maturation. Mattei S, Tan A et al. Proc Natl Acad Sci USA. 2018 Oct 2;115(40):E9401-E9410.

Structural basis for activation of voltage sensor domains in an ion channel TPC1. Kintzer AF, Green EM et al. Proc Natl Acad Sci USA. 2018 Sep 25;115(39):E9095-E9104.

Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin. Hu J, Worrall LJ et al. Nat Commun. 2018 Sep 21;9(1):3840.

Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA. Mishra S, Ahmed T et al. Sci Rep. 2018 Sep 11;8(1):13587.

Sub-2 Å Ewald curvature corrected structure of an AAV2 capsid variant. Tan YZ, Aiyer S et al. Nat Commun. 2018 Sep 7;9(1):3628.

Malaria parasite translocon structure and mechanism of effector export. Ho CM, Beck JR et al. Nature. 2018 Sep 6;561(7721):70-75.

Structural basis of pan-Ebolavirus neutralization by an antibody targeting the glycoprotein fusion loop. Murin CD, Bruhn JF et al. Cell Rep. 2018 Sep 4;24(10):2723-2732.e4.

Crystal structure of the Frizzled 4 receptor in a ligand-free state. Yang S, Wu Y et al. Nature. 2018 Aug 30;560(7720):666-670.

Electron-microscopy-based epitope mapping defines specificities of polyclonal antibodies elicited during HIV-1 BG505 envelope trimer immunization. Bianchi M, Turner HL et al. Immunity. 2018 Aug 21;49(2):288-300.e8.

Structure-based design of a monosaccharide ligand targeting galectin-8. Bohari MH, Yu X et al. ChemMedChem. 2018 Aug 20;13(16):1664-1672.

Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs. Matthies D, Bae C et al. eLife. 2018 Aug 15;7. pii: e37558.

Structure and analysis of R1 and R2 pyocin receptor-binding fibers. Buth SA, Shneider MM et al. Viruses. 2018 Aug 14;10(8). pii: E427.

Cryo-EM of the dynamin polymer assembled on lipid membrane. Kong L, Sochacki KA et al. Nature. 2018 Aug 9;560(7717):258-262.

Structural basis of cell wall anchoring by SLH domains in Paenibacillus alvei. Blackler RJ, López-Guzmán A et al. Nat Commun. 2018 Aug 7;9(1):3120.

Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles. Greenan GA, Keszthelyi B et al. eLife. 2018 Aug 6;7. pii: e36851.

Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5. Ge J, Elferich J et al. eLife. 2018 Aug 2;7. pii: e38770.

Cryo-EM structure of the αvβ8 integrin reveals a mechanism for stabilizing integrin extension. Cormier A, Campbell MG et al. Nat Struct Mol Biol. 2018 Aug;25(8):698-704.

A new HIV-1 Rev structure optimizes interaction with target RNA (RRE) for nuclear export. Watts NR, Eren E et al. J Struct Biol. 2018 Aug;203(2):102-108.

Expanded coverage of the 26S proteasome conformational landscape reveals mechanisms of peptidase gating. Eisele MR, Reed RG et al. Cell Rep. 2018 Jul 31;24(5):1301-1315.e5.

Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters. Baradaran R, Wang C et al. Nature. 2018 Jul 26;559(7715):580-584.

HIV-1 Nefs are cargo-sensitive AP-1 trimerization switches in tetherin downregulation. Morris KL, Buffalo CZ et al. Cell. 2018 Jul 26;174(3):659-671.e14.

Prespliceosome structure provides insights into spliceosome assembly and regulation. Plaschka C, Lin PC et al. Nature. 2018 Jul 19;559(7714):419-422.

Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser. Nogly P, Weinert T et al. Science. 2018 Jul 13;361(6398). pii: eaat0094.

Structural analysis of influenza vaccine virus-like particles reveals a multicomponent organization. McCraw DM, Gallagher JR et al. Sci Rep. 2018 Jul 9;8(1):10342.


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