home overview research resources outreach & training outreach & training visitors center visitors center search search

Quick Links

Recent Citations

A 12 Å carotenoid translocation in a photoswitch associated with cyanobacterial photoprotection. Leverenz RL, Sutter M et al. Science. 2015 Jun 26;348(6242):1463-6.

2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor. Bartesaghi A, Merk A et al. Science. 2015 Jun 5;348(6239):1147-51.

DOCK 6: Impact of new features and current docking performance. Allen WJ, Balius TE et al. J Comput Chem. 2015 Jun 5;36(15):1132-56.

Structural organization of an intact phycobilisome and its association with photosystem II. Chang L, Liu X et al. Cell Res. 2015 Jun;25(6):726-37.

Atomic structure of anthrax protective antigen pore elucidates toxin translocation. Jiang J, Pentelute BL et al. Nature. 2015 May 28;521(7553):545-9.

(Previously featured citations...)

Chimera Search

Google™ Search

News

January 9, 2015

Chimera production release 1.10.1 is now available. 64-bit builds are recommended for all capable platforms, and the 1.10 series will be the last to support OS X 10.6 and 10.7. See the release notes for details.

November 5, 2014

Chimera production release 1.10 is now available. 64-bit builds are recommended for all capable platforms, and v1.10 will be the last to support OS X 10.6 and 10.7. See the release notes for what's new.

October 23, 2014

A production release candidate (v1.10) is available; please try it and report any problems. 64-bit builds are now recommended for all capable platforms, and v1.10 will be the last to support OS X 10.6 and 10.7. See the release notes for what's new.

(Previous news...)

Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics, funded by the National Institutes of Health (NIGMS P41-GM103311).

Feature Highlight

5 comparative models
Model List dialog

Chimera Interface to Modeller

Chimera provides a graphical interface to running the program Modeller, either locally or via a web service hosted by the UCSF RBVI. Two types of calculations are available:

  • Comparative (homology) modeling. Theoretical models of a protein target are generated using at least one known related template structure and a target-template sequence alignment. There are several ways to generate these inputs in Chimera. See also the Comparative Modeling tutorial.

  • Building parts of a protein without using a template. Missing segments can be built de novo, or existing segments refined by generating additional possible conformations.
Modeller is developed by the Sali Lab.

(More features...)

Gallery Sample

Wasabi Receptor

The image shows the structure of the human TRPA1 ion channel (wasabi receptor) determined by electron cryo-microscopy, Protein Data Bank entry 3j9p. The four subunits of the tetramer are shown as ribbons in different colors over a dark-to-light gradient background. (More samples...)