Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugs. Farelli JD, Galvin BD et al. PLoS Pathog. 2014 Jul 3;10(7):e1004245.
Regulation of the mammalian elongation cycle by subunit rolling: a eukaryotic-specific ribosome rearrangement. Budkevich TV, Giesebrecht J et al. Cell. 2014 Jul 3;158(1):121-31.
Protruding knob-like proteins violate local symmetries in an icosahedral marine virus. Gipson P, Baker ML et al. Nat Commun. 2014 Jul 2;5:4278.
Enhancing UCSF Chimera through web services. Huang CC, Meng EC et al. Nucleic Acids Res. 2014 Jul;42(Web Server issue):W478-84.
Structural rearrangements of a polyketide synthase module during its catalytic cycle. Whicher JR, Dutta S et al. Nature. 2014 Jun 26;510(7506):560-4.(Previously featured citations...)
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Chimera production release 1.8.1 is now available. Changes since 1.8 are mainly to fix problems with Mac OS X 10.9 (Mavericks). See the release notes for further details and for a list of new features since the 1.7 release.(Previous news...)
UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics, funded by the National Institutes of Health (NIGMS P41-GM103311).
Volume data can be shown a single plane (or slab) at a time with the Planes feature in Volume Viewer. Plane display can be set to oscillate along the data X, Y, or Z axis, or the plane location can be specified interactively with a slider.(More features...)
Large ribosomal RNA is shown with individual bases depicted using solvent excluded molecular surfaces. Bases A, C, G, U are colored red, yellow, green, and blue. The surfaces were made with the Chimera multiscale tool in combination with the nucleic acid blobs plug-in. The image was raytraced using POVray.
Protein Data Bank model 1s72.(More samples...)