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Recent Citations

Cryo-EM structure of human adenovirus D26 reveals the conservation of structural organization among human adenoviruses. Yu X, Veesler D et al. Sci Adv. 2017 May 10;3(5):e1602670.

Relation between molecular electronic structure and nuclear spin-induced circular dichroism. Štěpánek P, Coriani S et al. Sci Rep. 2017 Apr 24;7:46617.

Architecture of a transcribing-translating expressome. Kohler R, Mooney RA et al. Science. 2017 Apr 14;356(6334):194-197.

Mediator structure and rearrangements required for holoenzyme formation. Tsai KL, Yu X et al. Nature. 2017 Apr 13;544(7649):196-201.

PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation. Wu R, Sanishvili R et al. Proc Natl Acad Sci USA. 2017 Apr 11;114(15):3891-3896.

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Chimera Search

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December 2, 2016

Chimera production release 1.11.2 is now available. This version has been updated to work with changes in NCBI Blast and to avoid crashes on Mac Sierra (see the release notes for details).

September 24, 2016

Production release candidate (version 1.11.2) is available, superseding 1.11.1. The new version has been updated to work with changes in NCBI Blast (see release notes). Please try it and report any problems.

August 27, 2016

A production release candidate (version 1.11.1) is now available. Please try it and report any problems. See the release notes for what's been fixed since 1.11. The 1.11 release series will be the last to support 32-bit builds.

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Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), funded by the National Institutes of Health (NIGMS P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

Consurf coloring and alignment

Showing ConSurf Results

The ConSurf Server provides results as Chimera Web data; after browser configuration, a single click displays the color-coded query structure and multiple sequence alignment with phylogenetic tree and custom headers in a locally installed copy of Chimera (details).

Special thanks to Elana Erez and the Ben-Tal and Pupko groups at Tel Aviv University, and to Fabian Glaser at the Technion.

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Gallery Sample

Peroxiredoxin Wreath

Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.

See also the RBVI holiday card gallery.

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