Crystal structure of the metazoan Nup62·Nup58·Nup54 nucleoporin complex. Chug H, Trakhanov S et al. Science. 2015 Oct 2;350(6256):106-10.
Structural basis for DNA strand separation by a hexameric replicative helicase. Chaban Y, Stead JA et al. Nucleic Acids Res. 2015 Sep 30;43(17):8551-63.
Structure of the native Sec61 protein-conducting channel. Pfeffer S, Burbaum L et al. Nat Commun. 2015 Sep 28;6:8403.
Cryo-EM shows the polymerase structures and a nonspooled genome within a dsRNA virus. Liu H, Cheng L. Science. 2015 Sep 18;349(6254):1347-50.
Structural basis of human parechovirus neutralization by human monoclonal antibodies. Shakeel S, Westerhuis BM et al. J Virol. 2015 Sep 15;89(18):9571-80.(Previously featured citations...)
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July 23, 2015
Chimera production release 1.10.2 is now available. Fixes include code signing for Mac OS X installation. The 1.10 series will be the last to support OS X 10.6 and 10.7. See the release notes for details.
January 9, 2015
Chimera production release 1.10.1 is now available. 64-bit builds are recommended for all capable platforms, and the 1.10 series will be the last to support OS X 10.6 and 10.7. See the release notes for details.
November 5, 2014
Chimera production release 1.10 is now available. 64-bit builds are recommended for all capable platforms, and v1.10 will be the last to support OS X 10.6 and 10.7. See the release notes for what's new.(Previous news...)
UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics, funded by the National Institutes of Health (NIGMS P41-GM103311).
Multiple sequence alignment of structure chains in Chimera or realignment of the sequences in an existing alignment can be performed using web services hosted by the UCSF RBVI. The following programs are provided:Multalign Viewer. (Sequences can also be added to an alignment one by one without a web service, but true multiple sequence alignment is often advantageous.) (More features...)
The image shows interactions of the delta-1 loop with the rest of hepatitis C virus RNA-dependent RNA polymerase (Protein Data Bank entry 1quv). Loop residues in contact with the rest of the structure (van der Waals overlap ≥ 0.01 Å) are displayed as sticks; interacting surface atoms are shown as red patches. (More samples...)