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Recent Citations
Structural characterization of closely related O-antigen lipopolysaccharide (LPS) chain length regulators. Kalynych S, Yao D et al. J Biol Chem. 2012 May 4;287(19):15696-705.
Structure and dynamics of calmodulin (CaM) bound to nitric oxide synthase peptides: Effects of a phosphomimetic CaM mutation. Piazza M, Futrega K et al. Biochemistry. 2012 May 1;51(17):3651-61.
Cryo-EM structure of a transcribing cypovirus. Yang C, Ji G et al. Proc Natl Acad Sci USA. 2012 Apr 17;109(16):6118-23.
EBs recognize a nucleotide-dependent structural cap at growing microtubule ends. Maurer SP, Fourniol FJ et al. Cell. 2012 Apr 13;149(2):371-82.
Structural insights into initial and intermediate steps of the ribosome-recycling process. Yokoyama T, Shaikh TR et al. EMBO J. 2012 Apr 4;31(7):1836-46.
(Previously featured citations...)Chimera Search
Google™ SearchNews
March 13, 2012
Chimera production release 1.6.1 is now available. The 1.6 release series will be the last to support Mac PowerPC platforms and OS X 10.5 (Leopard). See the release notes for new features since the 1.5 series and bugfixes since 1.6.
February 29, 2012
Chimera production release 1.6 is now available. This will be the last release supporting Mac PowerPC platforms and OS X 10.5 (Leopard). See the release notes for new features since the 1.5 release series.
January 26, 2012
A Chimera production release candidate (version 1.6) is available; please try it and report any problems. See the release notes for changes relative to previous versions.
(Previous news...)Upcoming Events
UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics, funded by the National Institutes of Health National Center for Research Resources (grant 2P41RR001081) and National Institute of General Medical Sciences (grant 9P41GM103311).
Feature Highlight
Chimera's Volume Viewer displays three-dimensional electron and light microscope data, X-ray density maps, electrostatic potential and other volumetric data. Contour surfaces, meshes and volumetric display styles are provided and thresholds can be changed interactively. Maps can be colored, sliced, segmented, and modifications can be saved. Markers can be placed and structures can be traced. The accompanying image shows a density map of Kelp fly virus from electron microscopy colored radially and with an octant cut out.
(More features...)Gallery Sample
Large ribosomal RNA is shown with individual bases depicted using solvent excluded molecular surfaces. Bases A, C, G, U are colored red, yellow, green, and blue. The surfaces were made with the Chimera multiscale tool in combination with the nucleic acid blobs plug-in. The image was raytraced using POVray.
Protein Data Bank model 1s72.
(More samples...)