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Recent Citations

Hydrogen positions in single nanocrystals revealed by electron diffraction. Palatinus L, Brázda P et al. Science. 2017 Jan 13;355(6321):166-169.

Architecture of the yeast small subunit processome. Chaker-Margot M, Barandun J et al. Science. 2017 Jan 13;355(6321):aal1880.

Principles for designing proteins with cavities formed by curved β sheets. Marcos E, Basanta B et al. Science. 2017 Jan 13;355(6321):201-206.

Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome. Passos DO, Li M et al. Science. 2017 Jan 6;355(6320):89-92.

A supramolecular assembly mediates lentiviral DNA integration. Ballandras-Colas A, Maskell DP et al. Science. 2017 Jan 6;355(6320):93-95.

(Previously featured citations...)

Chimera Search

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News

December 2, 2016

Chimera production release 1.11.2 is now available. This version has been updated to work with changes in NCBI Blast and to avoid crashes on Mac Sierra (see the release notes for details).

September 24, 2016

Production release candidate (version 1.11.2) is available, superseding 1.11.1. The new version has been updated to work with changes in NCBI Blast (see release notes). Please try it and report any problems.

August 27, 2016

A production release candidate (version 1.11.1) is now available. Please try it and report any problems. See the release notes for what's been fixed since 1.11. The 1.11 release series will be the last to support 32-bit builds.

(Previous news...)

Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), funded by the National Institutes of Health (NIGMS P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

Interactive Shadows

Interactive shadows (shadows that move as structures are moved) can be enabled in the Effects dialog or with the command set shadows. Click the image to show a small molecule rotating above a rectangular plane. This simple animation was made with the Chimera command script tumble.com. Interactive shadows also work with ribbons, surfaces, and other representations.

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Gallery Sample

Cavity and Tunnel Detection

Side-by-side views of a potassium channel structure (Protein Data Bank entry 1bl8) showing different approaches to cavity detection. On the left are molecular surface patches corresponding to the structure's two largest pockets by MS volume in the Computed Atlas of Surface Topography of proteins (CASTp) database. On the right is a tunnel in blue identified by the MolAxis server. Simple editing converted MolAxis output into a BILD file for display in Chimera. (More samples...)