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Recent Citations

Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Gates SN, Yokom AL et al. Science. 2017 Jul 21;357(6348):273-279.

Using molecular visualization to explore protein structure and function and enhance student facility with computational tools. Terrell CR, Listenberger LL. Biochem Mol Biol Educ. 2017 Jul 8;45(4):318-328.

Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1. Li Z, Han K et al. Nat Chem Biol. 2017 Jul;13(7):757-763.

Dual host specificity of phage SP6 is facilitated by tailspike rotation. Tu J, Park T et al. Virology. 2017 Jul;507:206-215.

Improved metrics for comparing structures of macromolecular assemblies determined by 3D electron-microscopy. Joseph AP, Lagerstedt I et al. J Struct Biol. 2017 Jul;199(1):12-26.

(Previously featured citations...)

Chimera Search

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News

December 2, 2016

Chimera production release 1.11.2 is now available. This version has been updated to work with changes in NCBI Blast and to avoid crashes on Mac Sierra (see the release notes for details).

September 24, 2016

Production release candidate (version 1.11.2) is available, superseding 1.11.1. The new version has been updated to work with changes in NCBI Blast (see release notes). Please try it and report any problems.

August 27, 2016

A production release candidate (version 1.11.1) is now available. Please try it and report any problems. See the release notes for what's been fixed since 1.11. The 1.11 release series will be the last to support 32-bit builds.

(Previous news...)

Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), funded by the National Institutes of Health (NIGMS P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

Space Navigator demonstration

Space Navigator Input Device

Space Navigator is an inexpensive ($60) USB input device from 3Dconnexion for moving and rotating models in 3 dimensions. This animation (8 Mb) shows docking a phage enzyme (PDB 1v0e) into an electron microscopy map (EMDB 1333) using a space navigator and mouse. Works with Windows and Mac Chimera versions (details).

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Gallery Sample

Wasabi Receptor

The image shows the structure of the human TRPA1 ion channel (wasabi receptor) determined by electron cryo-microscopy, Protein Data Bank entry 3j9p. The four subunits of the tetramer are shown as ribbons in different colors over a dark-to-light gradient background. (More samples...)