| 14 | * Boltz structure prediction in ChimeraX |
| 15 | - Demonstrated how to predict HIV protease dimer bound with a set of 50 ligands. |
| 16 | - Not yet in daily build. |
| 17 | - Benchmarks by others show ML ligand docking prediction is good for ligands and pockets that are similar to ones in training data (80% success), much worse if novel (20% success). |
| 18 | - Future Boltz plans include new features (templates, pocket specification, post-translational modifications...) and memory optimization to predict larger structures. |
| 19 | |
| 20 | * Animation examples |
| 21 | - Showed example animations from Nature and Science papers. |
| 22 | - Reviewed a list of problems in the example animations and tips to avoid them. |