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Opened 7 months ago

Last modified 7 months ago

#17222 assigned defect

ChimeraX bug report submission — at Initial Version

Reported by:	chimerax-bug-report@…	Owned by:
Priority:	normal	Milestone:
Component:	Third Party	Version:
Keywords:		Cc:	Tom Goddard
Blocked By:		Blocking:
Notify when closed:		Platform:	all
Project:	ChimeraX

Description

The following bug report has been submitted:
Platform:        macOS-15.0.1-arm64-arm-64bit
ChimeraX Version: 1.9 (2024-12-11 19:11:19 UTC)
Description
Replace this text with list of actions that caused this problem to occur

Log:
UCSF ChimeraX version: 1.9 (2024-12-11)  
© 2016-2024 Regents of the University of California. All rights reserved.  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/Manuscript/figures/figureA/supercomplexMapcoloredView1.cxs"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #2, grid size
500,500,500, pixel 1.21, shown at level 0.192, step 1, values float32  
Opened superComplexConsolidatedV1.cif map 3.5 as #4, grid size 226,226,275,
pixel 1.17, shown at level 0.106, step 1, values float32  
Opened volume difference as #5, grid size 500,500,500, pixel 1.21, shown at
level 0.185, step 1, values float32  
Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #1.1.1.1, grid size
500,500,500, pixel 1.21, shown at level 0.203, step 1, values float32  
Opened cryosparc_P43_J436_002_volume_map_sharp.mrc as #10, grid size
500,500,500, pixel 1.21, shown at level 0.131, step 1, values float32  
Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #11, grid size
500,500,500, pixel 1.21, shown at level 0.131, step 1, values float32  
Opened lipidLayer.mrc as #12, grid size 500,500,500, pixel 1.21, shown at
level 0.0696, step 1, values float32  
Restoring stepper: combination  
Log from Thu Mar 6 18:11:35 2025UCSF ChimeraX version: 1.9 (2024-12-11)  
© 2016-2024 Regents of the University of California. All rights reserved.  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV8.cxs"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #2, grid size
500,500,500, pixel 1.21, shown at level 0.296, step 1, values float32  
Opened superComplexConsolidatedV1.cif map 3.5 as #4, grid size 226,226,275,
pixel 1.17, shown at level 0.106, step 1, values float32  
Opened volume difference as #5, grid size 500,500,500, pixel 1.21, shown at
level 0.185, step 1, values float32  
Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #1.1.1.1, grid size
500,500,500, pixel 1.21, shown at level 0.203, step 1, values float32  
Restoring stepper: combination  
Log from Thu Mar 6 15:08:05 2025UCSF ChimeraX version: 1.9 (2024-12-11)  
© 2016-2024 Regents of the University of California. All rights reserved.  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV6.cxs"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #1.1.1.1, grid size
500,500,500, pixel 1.21, shown at level 0.335, step 1, values float32  
Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #2, grid size
500,500,500, pixel 1.21, shown at level 0.296, step 1, values float32  
Opened superComplexConsolidatedV1.cif map 3.5 as #4, grid size 226,226,275,
pixel 1.17, shown at level 0.106, step 1, values float32  
Opened volume difference as #5, grid size 500,500,500, pixel 1.21, shown at
level 0.185, step 1, values float32  
Restoring stepper: superComplexConsolidatedV1.cif  
Log from Thu Jan 16 15:16:15 2025UCSF ChimeraX version: 1.9 (2024-12-11)  
© 2016-2024 Regents of the University of California. All rights reserved.  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV6.cxs"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #1.1.1.1, grid size
500,500,500, pixel 1.21, shown at level 0.255, step 1, values float32  
Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #2, grid size
500,500,500, pixel 1.21, shown at level 0.296, step 1, values float32  
Opened superComplexConsolidatedV1.cif map 3.5 as #4, grid size 226,226,275,
pixel 1.17, shown at level 0.106, step 1, values float32  
Opened volume difference as #5, grid size 500,500,500, pixel 1.21, shown at
level 0.255, step 1, values float32  
Restoring stepper: superComplexConsolidatedV1.cif  
Log from Wed Jan 15 18:19:59 2025UCSF ChimeraX version: 1.9 (2024-12-11)  
© 2016-2024 Regents of the University of California. All rights reserved.  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV5.cxs"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #1.1.1.1, grid size
500,500,500, pixel 1.21, shown at level 0.255, step 1, values float32  
Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #2, grid size
500,500,500, pixel 1.21, shown at level 0.296, step 1, values float32  
Opened superComplexConsolidatedV1.cif map 3.5 as #4, grid size 226,226,275,
pixel 1.17, shown at level 0.106, step 1, values float32  
Opened volume difference as #5, grid size 500,500,500, pixel 1.21, shown at
level 0.255, step 1, values float32  
Restoring stepper: superComplexConsolidatedV1.cif  
Log from Wed Jan 15 18:04:27 2025UCSF ChimeraX version: 1.9 (2024-12-11)  
© 2016-2024 Regents of the University of California. All rights reserved.  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV1.cxs"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #5, grid size
500,500,500, pixel 1.21, shown at level 0.118, step 2, values float32  
Log from Tue Jan 14 10:38:39 2025

> set selectionWidth 4

Done loading forcefield  
UCSF ChimeraX version: 1.9 (2024-12-11)  
© 2016-2024 Regents of the University of California. All rights reserved.  
How to cite UCSF ChimeraX  

> isolde set simFidelityMode Medium/Medium

ISOLDE: setting sim fidelity mode to Medium/Medium  
nonbonded_cutoff_distance = 0.900000  
use_gbsa = True  
gbsa_cutoff = 1.100000  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-IV2-II/cryosparc_P43_J454_map_sharp-
> EMHanced.mrc"

Opened cryosparc_P43_J454_map_sharp-EMHanced.mrc as #1, grid size 500,500,500,
pixel 1.21, shown at level 0.000679, step 2, values float32  

> volume #1 level 0.01917

> volume #1 step 1

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-IV2-II/cryosparc_P43_J453_map_sharp-
> EMHanced.mrc"

Opened cryosparc_P43_J453_map_sharp-EMHanced.mrc as #2, grid size 500,500,500,
pixel 1.21, shown at level 0.00075, step 2, values float32  

> volume #2 step 1

> volume #2 level 0.01913

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp.mrc"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #3, grid size
500,500,500, pixel 1.21, shown at level 0.118, step 2, values float32  

> volume #3 step 1

> volume #3 level 0.1415

> volume #3 level 0.1934

> show #!1 models

> volume #1 level -0.00379

> volume #1 level 0.023

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J436_002_volume_map_sharp_NOSEQ/ligandsDetection/manualRefinementStep8WithLigs.cif"

Summary of feedback from opening
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J436_002_volume_map_sharp_NOSEQ/ligandsDetection/manualRefinementStep8WithLigs.cif  
---  
warnings | Unknown polymer entity '1' on line 281  
Unknown polymer entity '2' on line 3139  
Unknown polymer entity '3' on line 4765  
Unknown polymer entity '4' on line 6243  
Unknown polymer entity '5' on line 10007  
37 messages similar to the above omitted  
Atom HN3 is not in the residue template for 3PE /LG:1000  
Atom HN3 is not in the residue template for 3PE /LO:1000  
Atom HN3 is not in the residue template for 3PE /Np:1001  
Atom HN3 is not in the residue template for 3PE /t7:1001  
Atom HN3 is not in the residue template for 3PE /tb:1001  
Atom OMA is not in the residue template for HEM /HM:1  
Atom HO11 is not in the residue template for HEA /HN:3  
Atom HO11 is not in the residue template for HEA /HN:4  
Atom C13 is not in the residue template for HE9 /HM:1  
Atom HO11 is not in the residue template for HEA /HM:2  
Missing or incomplete sequence information. Inferred polymer connectivity.  
  
  
Chain information for manualRefinementStep8WithLigs.cif #4  
---  
Chain | Description  
AG t3 | No description available  
Ar t4 | No description available  
CS | No description available  
I0 tb | No description available  
I2 | No description available  
Ii | No description available  
Il td | No description available  
Ix t9 | No description available  
Iy tc | No description available  
J4 | No description available  
J6 t1 | No description available  
JI | No description available  
JJ t6 | No description available  
JN tf | No description available  
Jw t8 | No description available  
Jx | No description available  
K5 | No description available  
KI t5 | No description available  
Ke | No description available  
Kp | No description available  
Ks te | No description available  
L3 | No description available  
LG | No description available  
LO t2 | No description available  
LR | No description available  
LY tg | No description available  
Lb | No description available  
Lr | No description available  
M | No description available  
MC | No description available  
Mg | No description available  
Mh | No description available  
Ml | No description available  
Mq | No description available  
Mr t0 | No description available  
Mw | No description available  
Mx | No description available  
NF | No description available  
NM | No description available  
Np t7 | No description available  
TB | No description available  
Y ta | No description available  
  

> select add #4

166871 atoms, 169315 bonds, 40 pseudobonds, 10067 residues, 3 models selected  

> hide sel atoms

> show sel cartoons

> hide #!1 models

> hide #!3 models

> show #!3 models

> hide #!3 models

> show #!3 models

> show #!1 models

> hide #!1 models

> hide #!3 models

> show #!3 models

> hide #!3 models

> show #!3 models

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/CV-Full/cryosparc_P31_J281_004_volume_map_sharp--VC-
> Conf1/complexVconsolidation/complexVconsolidatedV29.cif"

Summary of feedback from opening
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/CV-Full/cryosparc_P31_J281_004_volume_map_sharp--VC-
Conf1/complexVconsolidation/complexVconsolidatedV29.cif  
---  
warnings | Unknown polymer entity '1' on line 202  
Unknown polymer entity '2' on line 1252  
Unknown polymer entity '3' on line 6584  
Unknown polymer entity '4' on line 13903  
Unknown polymer entity '5' on line 22164  
33 messages similar to the above omitted  
Atom HA2 is not in the residue template for GLU /A:176  
Atom H5' is not in the residue template for ATP /AU:2000  
Atom H is not in the residue template for ALA /B:23  
Atom H is not in the residue template for SER /C:85  
Atom H is not in the residue template for ILE /C0:33  
Atom H is not in the residue template for ILE /C1:33  
Atom H is not in the residue template for ILE /C2:33  
2 messages similar to the above omitted  
Too many hydrogens missing from residue template(s) to warn about  
Missing or incomplete sequence information. Inferred polymer connectivity.  
  
  
Chain information for complexVconsolidatedV29.cif #5  
---  
Chain | Description  
A | No description available  
A0 | No description available  
AU | No description available  
Ab | No description available  
Aj | No description available  
Aq | No description available  
B | No description available  
BI | No description available  
BK | No description available  
BP | No description available  
C | No description available  
C0 C1 C2 C3 C5 C6 C7 C8 C9 | No description available  
C4 | No description available  
D | No description available  
D6 | No description available  
E | No description available  
E1 | No description available  
E4 | No description available  
Eg | No description available  
Ek | No description available  
Eq | No description available  
Es | No description available  
Ev | No description available  
F9 | No description available  
FF | No description available  
FH | No description available  
FL | No description available  
FO | No description available  
Fy | No description available  
Fz | No description available  
GT | No description available  
IE | No description available  
IY | No description available  
JC | No description available  
P | No description available  
R | No description available  
S | No description available  
a | No description available  
  

> select add #5

292434 atoms, 297470 bonds, 52 pseudobonds, 17932 residues, 5 models selected  

> select subtract #4

125563 atoms, 128155 bonds, 12 pseudobonds, 7865 residues, 2 models selected  

> hide sel atoms

> show sel cartoons

> hide #!3 models

> hide #!4 models

> show #!4 models

> hide #!4 models

> show #!4 models

> align #5/E4:137-156@CA #4/MC:137-156@CA

Missing required "to_atoms" argument  

> align #5/E4:137-156@CA toAtoms #4/MC:137-156@CA

RMSD between 20 atom pairs is 2.087 angstroms  

> color #5@C blue

> color #5@C mediumorchid

> select clear

> color #4@C mediumturquoise

> align #5/Ev:138-148@CA toAtoms #4/Lr:138-148@CA

RMSD between 11 atom pairs is 0.742 angstroms  

> show #!3 models

> hide #!3 models

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ.cif"

Summary of feedback from opening
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ.cif  
---  
warnings | Missing entity information. Treating each chain as a separate entity.  
Missing or incomplete sequence information. Inferred polymer connectivity.  
  
  
Chain information for cryosparc_P43_J450_008_volume_map_sharp_NOSEQ.cif #6  
---  
Chain | Description  
1 CY | No description available  
3 | No description available  
6 | No description available  
8 | No description available  
9 Au | No description available  
A | No description available  
A3 DB | No description available  
A4 | No description available  
A6 | No description available  
A8 | No description available  
A9 | No description available  
AA | No description available  
AB | No description available  
AD | No description available  
AE | No description available  
AF | No description available  
AG AJ EH | No description available  
AH | No description available  
AK | No description available  
AL | No description available  
AN Fo | No description available  
AO | No description available  
AP | No description available  
AQ | No description available  
AR BH DP EC | No description available  
AS CS | No description available  
AV | No description available  
AZ Bz CJ CP CZ Cr t | No description available  
Aa | No description available  
Ab | No description available  
Ad | No description available  
Ae | No description available  
Am M | No description available  
An | No description available  
Ao | No description available  
Aq | No description available  
Ar | No description available  
As BB Bn | No description available  
Ax | No description available  
Ay BK | No description available  
Az | No description available  
B1 | No description available  
B2 | No description available  
B3 | No description available  
B5 | No description available  
B9 | No description available  
BC EV | No description available  
BJ | No description available  
BL | No description available  
BO | No description available  
BP | No description available  
BQ | No description available  
BW | No description available  
BY C u | No description available  
Bb o | No description available  
Bd | No description available  
Bf | No description available  
Bg Ce | No description available  
Bp | No description available  
Bq | No description available  
Bt | No description available  
Bv | No description available  
Bw | No description available  
By w | No description available  
C2 | No description available  
C3 | No description available  
C4 | No description available  
C7 | No description available  
CA | No description available  
CE Ca | No description available  
CG | No description available  
CQ p | No description available  
CR | No description available  
Cg EY | No description available  
Cv | No description available  
Cz | No description available  
D | No description available  
D3 | No description available  
DI | No description available  
DZ | No description available  
Di | No description available  
Dr | No description available  
E | No description available  
E0 | No description available  
E1 | No description available  
E2 | No description available  
E3 | No description available  
E4 | No description available  
E5 | No description available  
E6 | No description available  
E7 | No description available  
E8 | No description available  
E9 | No description available  
EJ | No description available  
EK | No description available  
Ec | No description available  
Ef | No description available  
Eg | No description available  
Eh | No description available  
Ei | No description available  
Ej | No description available  
Ek | No description available  
El | No description available  
Em | No description available  
En | No description available  
Eo | No description available  
Ep | No description available  
Eq | No description available  
Er | No description available  
Es | No description available  
Et | No description available  
Eu | No description available  
Ev | No description available  
Ew | No description available  
Ex | No description available  
Ey | No description available  
Ez | No description available  
F0 | No description available  
F1 | No description available  
F2 Fq | No description available  
F3 | No description available  
F4 | No description available  
F5 | No description available  
F6 | No description available  
F7 | No description available  
F8 | No description available  
F9 | No description available  
FA | No description available  
FB | No description available  
FC | No description available  
FD | No description available  
FE | No description available  
FF | No description available  
FG | No description available  
FH | No description available  
FI | No description available  
FJ | No description available  
FK | No description available  
FL | No description available  
FM | No description available  
FN | No description available  
FO | No description available  
FP | No description available  
FQ | No description available  
FR | No description available  
FS | No description available  
FT | No description available  
FU | No description available  
FV | No description available  
FW | No description available  
FX | No description available  
FY | No description available  
FZ | No description available  
Fa | No description available  
Fb | No description available  
Fc | No description available  
Fd | No description available  
Fe | No description available  
Ff GH | No description available  
Fg | No description available  
Fh | No description available  
Fi | No description available  
Fj | No description available  
Fk | No description available  
Fl | No description available  
Fm | No description available  
Fn | No description available  
Fp | No description available  
Fr | No description available  
Fs | No description available  
Ft | No description available  
Fu | No description available  
Fv | No description available  
Fw | No description available  
Fx | No description available  
Fy | No description available  
Fz | No description available  
G X | No description available  
GA | No description available  
GB | No description available  
GC | No description available  
GD | No description available  
GE | No description available  
GF | No description available  
GG | No description available  
GI | No description available  
GJ | No description available  
GK | No description available  
GL | No description available  
GM | No description available  
GN | No description available  
GO | No description available  
GP | No description available  
GQ | No description available  
GR | No description available  
GS | No description available  
GT | No description available  
J | No description available  
L | No description available  
N | No description available  
O | No description available  
P | No description available  
Q | No description available  
R | No description available  
S | No description available  
T | No description available  
U | No description available  
V | No description available  
W | No description available  
Y | No description available  
Z | No description available  
a | No description available  
c | No description available  
d | No description available  
e | No description available  
g | No description available  
h | No description available  
i | No description available  
j | No description available  
l | No description available  
m | No description available  
n | No description available  
q | No description available  
r | No description available  
v | No description available  
x | No description available  
y | No description available  
  

> select add #6

26819 atoms, 27073 bonds, 3296 residues, 1 model selected  

> hide sel atoms

> show sel cartoons

Computing secondary structure  

> color #6@C greenyellow

> select clear

> show #!3 models

> volume #3 level 0.1367

> hide #!5 models

> hide #!3 models

> show #!3 models

> hide #!3 models

> show #!3 models

> hide #!3 models

> show #!3 models

> hide #!3 models

> show #!3 models

> hide #!3 models

> show #!3 models

> hide #!3 models

> hide #6 models

> show #6 models

> show #!5 models

> hide #6 models

> show #6 models

> hide #!4 models

> show #!4 models

> hide #!5 models

> show #!5 models

> hide #6 models

> combine #4,5

> hide #!5 models

> hide #!4 models

> select #7MC

Expected an objects specifier or a keyword  

> select #7/MC

1871 atoms, 1890 bonds, 1 pseudobond, 110 residues, 2 models selected  

> delete #3/MC

> close #1

> close #3

> close #2

> rename #7 id #3

> delete #3/MC

> delete #3/I2

> select #3/Lr

5619 atoms, 5702 bonds, 2 pseudobonds, 344 residues, 2 models selected  

> delete #3/Lr

> delete #3/Mw

Undo failed, probably because structures have been modified.  

> select #3/Mh

1043 atoms, 1067 bonds, 59 residues, 1 model selected  

> delete #3/Mh

> select #3/Mx

727 atoms, 736 bonds, 42 residues, 1 model selected  

> delete #3/Mx

> select #3/Ii

1448 atoms, 1472 bonds, 2 pseudobonds, 87 residues, 2 models selected  

> delete #3/Ii

> select #3/Lb

1851 atoms, 1883 bonds, 115 residues, 1 model selected  

> delete #3/Lb

> select #3/Mi

Nothing selected  

> select #3/Ml

1230 atoms, 1245 bonds, 71 residues, 1 model selected  

> delete #3/Ml

> select #3/J4

1544 atoms, 1569 bonds, 1 pseudobond, 95 residues, 2 models selected  

> delete #3/J4

> select #3/CS

1478 atoms, 1496 bonds, 1 pseudobond, 89 residues, 2 models selected  

> delete #3/CS

> select #3/P

162 atoms, 162 bonds, 10 residues, 1 model selected  

> select #3/Eg

327 atoms, 334 bonds, 21 residues, 1 model selected  

> show #!4 models

> hide #!4 models

> delete #3/P

> delete #3/Eg

> delete #3/S

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp.mrc"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #1, grid size
500,500,500, pixel 1.21, shown at level 0.118, step 2, values float32  

> close #1

> rename #4 id #1

> rename #5 id #2

> rename #6 id #4

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp.mrc"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #5, grid size
500,500,500, pixel 1.21, shown at level 0.118, step 2, values float32  

> save /Users/rafaelrocha/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV1.cxs

——— End of log from Tue Jan 14 10:38:39 2025 ———

opened ChimeraX session  

> close #4

> close #5

> close #2

> close #1

> delete #3@H*

> rename #3 id #1

> cd "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation"

Current working directory is:
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation  

> runscript /Users/rafaelrocha/Library/CloudStorage/OneDrive-
> Personal/GitHub/KRSPs/modelangeloScripts/correctStructureSequences.py False

> info #1 saveFile chainsInfoTMP.txt

> select #1/AG

1430 atoms, 1462 bonds, 179 residues, 1 model selected  

> save chainsTMP/AG_uu.pdb format pdb models #1/AG selectedOnly true

> open chainsTMP/AG_uu_Mod.pdb

Chain information for AG_uu_Mod.pdb #2  
---  
Chain | Description  
AG | No description available  
  

> select #1/Ar

831 atoms, 860 bonds, 96 residues, 1 model selected  

> save chainsTMP/Ar_ul.pdb format pdb models #1/Ar selectedOnly true

> open chainsTMP/Ar_ul_Mod.pdb

Chain information for Ar_ul_Mod.pdb #3  
---  
Chain | Description  
Ar | No description available  
  

> select #1/I0

1884 atoms, 1936 bonds, 225 residues, 1 model selected  

> save chainsTMP/I0_un.pdb format pdb models #1/I0 selectedOnly true

> open chainsTMP/I0_un_Mod.pdb

Chain information for I0_un_Mod.pdb #4  
---  
Chain | Description  
I0 | No description available  
  

> select #1/Il

664 atoms, 688 bonds, 79 residues, 1 model selected  

> save chainsTMP/Il_ul.pdb format pdb models #1/Il selectedOnly true

> open chainsTMP/Il_ul_Mod.pdb

Chain information for Il_ul_Mod.pdb #5  
---  
Chain | Description  
Il | No description available  
  

> select #1/Ix

1101 atoms, 1145 bonds, 128 residues, 1 model selected  

> save chainsTMP/Ix_ul.pdb format pdb models #1/Ix selectedOnly true

> open chainsTMP/Ix_ul_Mod.pdb

Chain information for Ix_ul_Mod.pdb #6  
---  
Chain | Description  
Ix | No description available  
  

> select #1/Iy

751 atoms, 763 bonds, 94 residues, 1 model selected  

> save chainsTMP/Iy_ul.pdb format pdb models #1/Iy selectedOnly true

> open chainsTMP/Iy_ul_Mod.pdb

Chain information for Iy_ul_Mod.pdb #7  
---  
Chain | Description  
Iy | No description available  
  

> select #1/J6

1621 atoms, 1663 bonds, 198 residues, 1 model selected  

> save chainsTMP/J6_un.pdb format pdb models #1/J6 selectedOnly true

> open chainsTMP/J6_un_Mod.pdb

Chain information for J6_un_Mod.pdb #8  
---  
Chain | Description  
J6 | No description available  
  

> select #1/JI

3646 atoms, 3705 bonds, 1 pseudobond, 475 residues, 2 models selected  

> save chainsTMP/JI_uu.pdb format pdb models #1/JI selectedOnly true

> open chainsTMP/JI_uu_Mod.pdb

Chain information for JI_uu_Mod.pdb #9  
---  
Chain | Description  
JI | No description available  
  

> select #1/JJ

4683 atoms, 4842 bonds, 552 residues, 1 model selected  

> save chainsTMP/JJ_uu.pdb format pdb models #1/JJ selectedOnly true

> open chainsTMP/JJ_uu_Mod.pdb

Chain information for JJ_uu_Mod.pdb #10  
---  
Chain | Description  
JJ | No description available  
  

> select #1/JN

870 atoms, 900 bonds, 107 residues, 1 model selected  

> save chainsTMP/JN_uu.pdb format pdb models #1/JN selectedOnly true

> open chainsTMP/JN_uu_Mod.pdb

Chain information for JN_uu_Mod.pdb #11  
---  
Chain | Description  
JN | No description available  
  

> select #1/Jw

1146 atoms, 1193 bonds, 125 residues, 1 model selected  

> save chainsTMP/Jw_ul.pdb format pdb models #1/Jw selectedOnly true

> open chainsTMP/Jw_ul_Mod.pdb

Chain information for Jw_ul_Mod.pdb #12  
---  
Chain | Description  
Jw | No description available  
  

> select #1/Jx

948 atoms, 976 bonds, 114 residues, 1 model selected  

> save chainsTMP/Jx_ul.pdb format pdb models #1/Jx selectedOnly true

> open chainsTMP/Jx_ul_Mod.pdb

Chain information for Jx_ul_Mod.pdb #13  
---  
Chain | Description  
Jx | No description available  
  

> select #1/K5

3795 atoms, 3864 bonds, 6 pseudobonds, 498 residues, 2 models selected  

> save chainsTMP/K5_un.pdb format pdb models #1/K5 selectedOnly true

> open chainsTMP/K5_un_Mod.pdb

Chain information for K5_un_Mod.pdb #14  
---  
Chain | Description  
K5 | No description available  
  

> select #1/KI

1666 atoms, 1730 bonds, 201 residues, 1 model selected  

> save chainsTMP/KI_uu.pdb format pdb models #1/KI selectedOnly true

> open chainsTMP/KI_uu_Mod.pdb

Chain information for KI_uu_Mod.pdb #15  
---  
Chain | Description  
KI | No description available  
  

> select #1/Ke

741 atoms, 764 bonds, 95 residues, 1 model selected  

> save chainsTMP/Ke_ul.pdb format pdb models #1/Ke selectedOnly true

> open chainsTMP/Ke_ul_Mod.pdb

Chain information for Ke_ul_Mod.pdb #16  
---  
Chain | Description  
Ke | No description available  
  

> select #1/Kp

1379 atoms, 1414 bonds, 172 residues, 1 model selected  

> save chainsTMP/Kp_ul.pdb format pdb models #1/Kp selectedOnly true

> open chainsTMP/Kp_ul_Mod.pdb

Chain information for Kp_ul_Mod.pdb #17  
---  
Chain | Description  
Kp | No description available  
  

> select #1/Ks

1327 atoms, 1375 bonds, 153 residues, 1 model selected  

> save chainsTMP/Ks_ul.pdb format pdb models #1/Ks selectedOnly true

> open chainsTMP/Ks_ul_Mod.pdb

Chain information for Ks_ul_Mod.pdb #18  
---  
Chain | Description  
Ks | No description available  
  

> select #1/L3

1230 atoms, 1253 bonds, 3 pseudobonds, 157 residues, 2 models selected  

> save chainsTMP/L3_un.pdb format pdb models #1/L3 selectedOnly true

> open chainsTMP/L3_un_Mod.pdb

Chain information for L3_un_Mod.pdb #19  
---  
Chain | Description  
L3 | No description available  
  

> select #1/LG

932 atoms, 954 bonds, 105 residues, 1 model selected  

> save chainsTMP/LG_uu.pdb format pdb models #1/LG selectedOnly true

> open chainsTMP/LG_uu_Mod.pdb

Chain information for LG_uu_Mod.pdb #20  
---  
Chain | Description  
LG | No description available  
  

> select #1/LO

2582 atoms, 2626 bonds, 308 residues, 1 model selected  

> save chainsTMP/LO_uu.pdb format pdb models #1/LO selectedOnly true

> open chainsTMP/LO_uu_Mod.pdb

Chain information for LO_uu_Mod.pdb #21  
---  
Chain | Description  
LO | No description available  
  

> select #1/LR

554 atoms, 561 bonds, 71 residues, 1 model selected  

> save chainsTMP/LR_uu.pdb format pdb models #1/LR selectedOnly true

> open chainsTMP/LR_uu_Mod.pdb

Chain information for LR_uu_Mod.pdb #22  
---  
Chain | Description  
LR | No description available  
  

> select #1/LY

1390 atoms, 1441 bonds, 165 residues, 1 model selected  

> save chainsTMP/LY_uu.pdb format pdb models #1/LY selectedOnly true

> open chainsTMP/LY_uu_Mod.pdb

Chain information for LY_uu_Mod.pdb #23  
---  
Chain | Description  
LY | No description available  
  

> select #1/M

819 atoms, 841 bonds, 102 residues, 1 model selected  

> save chainsTMP/M_u.pdb format pdb models #1/M selectedOnly true

> open chainsTMP/M_u_Mod.pdb

Chain information for M_u_Mod.pdb #24  
---  
Chain | Description  
M | No description available  
  

> select #1/Mg

1821 atoms, 1875 bonds, 215 residues, 1 model selected  

> save chainsTMP/Mg_ul.pdb format pdb models #1/Mg selectedOnly true

> open chainsTMP/Mg_ul_Mod.pdb

Chain information for Mg_ul_Mod.pdb #25  
---  
Chain | Description  
Mg | No description available  
  

> select #1/Mq

474 atoms, 492 bonds, 57 residues, 1 model selected  

> save chainsTMP/Mq_ul.pdb format pdb models #1/Mq selectedOnly true

> open chainsTMP/Mq_ul_Mod.pdb

Chain information for Mq_ul_Mod.pdb #26  
---  
Chain | Description  
Mq | No description available  
  

> select #1/Mr

852 atoms, 882 bonds, 110 residues, 1 model selected  

> save chainsTMP/Mr_ul.pdb format pdb models #1/Mr selectedOnly true

> open chainsTMP/Mr_ul_Mod.pdb

Chain information for Mr_ul_Mod.pdb #27  
---  
Chain | Description  
Mr | No description available  
  

> select #1/NF

1651 atoms, 1677 bonds, 1 pseudobond, 212 residues, 2 models selected  

> save chainsTMP/NF_uu.pdb format pdb models #1/NF selectedOnly true

> open chainsTMP/NF_uu_Mod.pdb

Chain information for NF_uu_Mod.pdb #28  
---  
Chain | Description  
NF | No description available  
  

> select #1/NM

504 atoms, 518 bonds, 63 residues, 1 model selected  

> save chainsTMP/NM_uu.pdb format pdb models #1/NM selectedOnly true

> open chainsTMP/NM_uu_Mod.pdb

Chain information for NM_uu_Mod.pdb #29  
---  
Chain | Description  
NM | No description available  
  

> select #1/Np

2489 atoms, 2578 bonds, 285 residues, 1 model selected  

> save chainsTMP/Np_ul.pdb format pdb models #1/Np selectedOnly true

> open chainsTMP/Np_ul_Mod.pdb

Chain information for Np_ul_Mod.pdb #30  
---  
Chain | Description  
Np | No description available  
  

> select #1/TB

479 atoms, 485 bonds, 64 residues, 1 model selected  

> save chainsTMP/TB_uu.pdb format pdb models #1/TB selectedOnly true

> open chainsTMP/TB_uu_Mod.pdb

Chain information for TB_uu_Mod.pdb #31  
---  
Chain | Description  
TB | No description available  
  

> select #1/Y

1742 atoms, 1789 bonds, 211 residues, 1 model selected  

> save chainsTMP/Y_u.pdb format pdb models #1/Y selectedOnly true

> open chainsTMP/Y_u_Mod.pdb

Chain information for Y_u_Mod.pdb #32  
---  
Chain | Description  
Y | No description available  
  

> select #1/t0

853 atoms, 883 bonds, 110 residues, 1 model selected  

> save chainsTMP/t0_ln.pdb format pdb models #1/t0 selectedOnly true

> open chainsTMP/t0_ln_Mod.pdb

Chain information for t0_ln_Mod.pdb #33  
---  
Chain | Description  
t0 | No description available  
  

> select #1/t1

1621 atoms, 1663 bonds, 198 residues, 1 model selected  

> save chainsTMP/t1_ln.pdb format pdb models #1/t1 selectedOnly true

> open chainsTMP/t1_ln_Mod.pdb

Chain information for t1_ln_Mod.pdb #34  
---  
Chain | Description  
t1 | No description available  
  

> select #1/t2

2478 atoms, 2524 bonds, 306 residues, 1 model selected  

> save chainsTMP/t2_ln.pdb format pdb models #1/t2 selectedOnly true

> open chainsTMP/t2_ln_Mod.pdb

Chain information for t2_ln_Mod.pdb #35  
---  
Chain | Description  
t2 | No description available  
  

> select #1/t3

1430 atoms, 1462 bonds, 179 residues, 1 model selected  

> save chainsTMP/t3_ln.pdb format pdb models #1/t3 selectedOnly true

> open chainsTMP/t3_ln_Mod.pdb

Chain information for t3_ln_Mod.pdb #36  
---  
Chain | Description  
t3 | No description available  
  

> select #1/t4

831 atoms, 860 bonds, 96 residues, 1 model selected  

> save chainsTMP/t4_ln.pdb format pdb models #1/t4 selectedOnly true

> open chainsTMP/t4_ln_Mod.pdb

Chain information for t4_ln_Mod.pdb #37  
---  
Chain | Description  
t4 | No description available  
  

> select #1/t5

1666 atoms, 1730 bonds, 201 residues, 1 model selected  

> save chainsTMP/t5_ln.pdb format pdb models #1/t5 selectedOnly true

> open chainsTMP/t5_ln_Mod.pdb

Chain information for t5_ln_Mod.pdb #38  
---  
Chain | Description  
t5 | No description available  
  

> select #1/t6

4626 atoms, 4785 bonds, 552 residues, 1 model selected  

> save chainsTMP/t6_ln.pdb format pdb models #1/t6 selectedOnly true

> open chainsTMP/t6_ln_Mod.pdb

Chain information for t6_ln_Mod.pdb #39  
---  
Chain | Description  
t6 | No description available  
  

> select #1/t7

2489 atoms, 2579 bonds, 285 residues, 1 model selected  

> save chainsTMP/t7_ln.pdb format pdb models #1/t7 selectedOnly true

> open chainsTMP/t7_ln_Mod.pdb

Chain information for t7_ln_Mod.pdb #40  
---  
Chain | Description  
t7 | No description available  
  

> select #1/t8

1146 atoms, 1193 bonds, 125 residues, 1 model selected  

> save chainsTMP/t8_ln.pdb format pdb models #1/t8 selectedOnly true

> open chainsTMP/t8_ln_Mod.pdb

Chain information for t8_ln_Mod.pdb #41  
---  
Chain | Description  
t8 | No description available  
  

> select #1/t9

1102 atoms, 1146 bonds, 128 residues, 1 model selected  

> save chainsTMP/t9_ln.pdb format pdb models #1/t9 selectedOnly true

> open chainsTMP/t9_ln_Mod.pdb

Chain information for t9_ln_Mod.pdb #42  
---  
Chain | Description  
t9 | No description available  
  

> select #1/ta

1688 atoms, 1736 bonds, 210 residues, 1 model selected  

> save chainsTMP/ta_ll.pdb format pdb models #1/ta selectedOnly true

> open chainsTMP/ta_ll_Mod.pdb

Chain information for ta_ll_Mod.pdb #43  
---  
Chain | Description  
ta | No description available  
  

> select #1/tb

2045 atoms, 2095 bonds, 227 residues, 1 model selected  

> save chainsTMP/tb_ll.pdb format pdb models #1/tb selectedOnly true

> open chainsTMP/tb_ll_Mod.pdb

Chain information for tb_ll_Mod.pdb #44  
---  
Chain | Description  
tb | No description available  
  

> select #1/tc

751 atoms, 763 bonds, 94 residues, 1 model selected  

> save chainsTMP/tc_ll.pdb format pdb models #1/tc selectedOnly true

> open chainsTMP/tc_ll_Mod.pdb

Chain information for tc_ll_Mod.pdb #45  
---  
Chain | Description  
tc | No description available  
  

> select #1/td

664 atoms, 688 bonds, 79 residues, 1 model selected  

> save chainsTMP/td_ll.pdb format pdb models #1/td selectedOnly true

> open chainsTMP/td_ll_Mod.pdb

Chain information for td_ll_Mod.pdb #46  
---  
Chain | Description  
td | No description available  
  

> select #1/te

1327 atoms, 1375 bonds, 153 residues, 1 model selected  

> save chainsTMP/te_ll.pdb format pdb models #1/te selectedOnly true

> open chainsTMP/te_ll_Mod.pdb

Chain information for te_ll_Mod.pdb #47  
---  
Chain | Description  
te | No description available  
  

> select #1/tf

870 atoms, 900 bonds, 107 residues, 1 model selected  

> save chainsTMP/tf_ll.pdb format pdb models #1/tf selectedOnly true

> open chainsTMP/tf_ll_Mod.pdb

Chain information for tf_ll_Mod.pdb #48  
---  
Chain | Description  
tf | No description available  
  

> select #1/tg

1347 atoms, 1399 bonds, 164 residues, 1 model selected  

> save chainsTMP/tg_ll.pdb format pdb models #1/tg selectedOnly true

> open chainsTMP/tg_ll_Mod.pdb

Chain information for tg_ll_Mod.pdb #49  
---  
Chain | Description  
tg | No description available  
  

> select #1/FD

53 atoms, 58 bonds, 1 residue, 1 model selected  

> save chainsTMP/FD_uu.pdb format pdb models #1/FD selectedOnly true

> open chainsTMP/FD_uu_Mod.pdb

> select #1/HM

120 atoms, 125 bonds, 8 pseudobonds, 3 residues, 2 models selected  

> save chainsTMP/HM_uu.pdb format pdb models #1/HM selectedOnly true

> open chainsTMP/HM_uu_Mod.pdb

> select #1/HN

120 atoms, 126 bonds, 8 pseudobonds, 2 residues, 2 models selected  

> save chainsTMP/HN_uu.pdb format pdb models #1/HN selectedOnly true

> open chainsTMP/HN_uu_Mod.pdb

> select #1/FS

19 atoms, 25 bonds, 3 residues, 1 model selected  

> save chainsTMP/FS_uu.pdb format pdb models #1/FS selectedOnly true

> open chainsTMP/FS_uu_Mod.pdb

> select #1/HO

43 atoms, 46 bonds, 4 pseudobonds, 1 residue, 2 models selected  

> save chainsTMP/HO_uu.pdb format pdb models #1/HO selectedOnly true

> open chainsTMP/HO_uu_Mod.pdb

> select #1/R

540 atoms, 564 bonds, 62 residues, 1 model selected  

> save chainsTMP/R_u.pdb format pdb models #1/R selectedOnly true

> open chainsTMP/R_u_Mod.pdb

Chain information for R_u_Mod.pdb #55  
---  
Chain | Description  
R | No description available  
  

> select #1/A

2659 atoms, 2704 bonds, 324 residues, 1 model selected  

> save chainsTMP/A_u.pdb format pdb models #1/A selectedOnly true

> open chainsTMP/A_u_Mod.pdb

Chain information for A_u_Mod.pdb #56  
---  
Chain | Description  
A | No description available  
  

> select #1/A0

3641 atoms, 3696 bonds, 482 residues, 1 model selected  

> save chainsTMP/A0_un.pdb format pdb models #1/A0 selectedOnly true

> open chainsTMP/A0_un_Mod.pdb

Chain information for A0_un_Mod.pdb #57  
---  
Chain | Description  
A0 | No description available  
  

> select #1/AU

4069 atoms, 4141 bonds, 2 pseudobonds, 525 residues, 2 models selected  

> save chainsTMP/AU_uu.pdb format pdb models #1/AU selectedOnly true

> open chainsTMP/AU_uu_Mod.pdb

Chain information for AU_uu_Mod.pdb #58  
---  
Chain | Description  
AU | No description available  
  

> select #1/Ab

3641 atoms, 3693 bonds, 1 pseudobond, 480 residues, 2 models selected  

> save chainsTMP/Ab_ul.pdb format pdb models #1/Ab selectedOnly true

> open chainsTMP/Ab_ul_Mod.pdb

Chain information for Ab_ul_Mod.pdb #59  
---  
Chain | Description  
Ab | No description available  
  

> select #1/Aj

3647 atoms, 3701 bonds, 483 residues, 1 model selected  

> save chainsTMP/Aj_ul.pdb format pdb models #1/Aj selectedOnly true

> open chainsTMP/Aj_ul_Mod.pdb

Chain information for Aj_ul_Mod.pdb #60  
---  
Chain | Description  
Aj | No description available  
  

> select #1/Aq

1320 atoms, 1347 bonds, 163 residues, 1 model selected  

> save chainsTMP/Aq_ul.pdb format pdb models #1/Aq selectedOnly true

> open chainsTMP/Aq_ul_Mod.pdb

Chain information for Aq_ul_Mod.pdb #61  
---  
Chain | Description  
Aq | No description available  
  

> select #1/B

1080 atoms, 1097 bonds, 138 residues, 1 model selected  

> save chainsTMP/B_u.pdb format pdb models #1/B selectedOnly true

> open chainsTMP/B_u_Mod.pdb

Chain information for B_u_Mod.pdb #62  
---  
Chain | Description  
B | No description available  
  

> select #1/BI

1334 atoms, 1361 bonds, 165 residues, 1 model selected  

> save chainsTMP/BI_uu.pdb format pdb models #1/BI selectedOnly true

> open chainsTMP/BI_uu_Mod.pdb

Chain information for BI_uu_Mod.pdb #63  
---  
Chain | Description  
BI | No description available  
  

> select #1/BK

4007 atoms, 4077 bonds, 2 pseudobonds, 520 residues, 2 models selected  

> save chainsTMP/BK_uu.pdb format pdb models #1/BK selectedOnly true

> open chainsTMP/BK_uu_Mod.pdb

Chain information for BK_uu_Mod.pdb #64  
---  
Chain | Description  
BK | No description available  
  

> select #1/BP

1338 atoms, 1365 bonds, 166 residues, 1 model selected  

> save chainsTMP/BP_uu.pdb format pdb models #1/BP selectedOnly true

> open chainsTMP/BP_uu_Mod.pdb

Chain information for BP_uu_Mod.pdb #65  
---  
Chain | Description  
BP | No description available  
  

> select #1/C

1907 atoms, 1933 bonds, 265 residues, 1 model selected  

> save chainsTMP/C_u.pdb format pdb models #1/C selectedOnly true

> open chainsTMP/C_u_Mod.pdb

Chain information for C_u_Mod.pdb #66  
---  
Chain | Description  
C | No description available  
  

> select #1/C0

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C0_un.pdb format pdb models #1/C0 selectedOnly true

> open chainsTMP/C0_un_Mod.pdb

Chain information for C0_un_Mod.pdb #67  
---  
Chain | Description  
C0 | No description available  
  

> select #1/C1

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C1_un.pdb format pdb models #1/C1 selectedOnly true

> open chainsTMP/C1_un_Mod.pdb

Chain information for C1_un_Mod.pdb #68  
---  
Chain | Description  
C1 | No description available  
  

> select #1/C2

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C2_un.pdb format pdb models #1/C2 selectedOnly true

> open chainsTMP/C2_un_Mod.pdb

Chain information for C2_un_Mod.pdb #69  
---  
Chain | Description  
C2 | No description available  
  

> select #1/C3

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C3_un.pdb format pdb models #1/C3 selectedOnly true

> open chainsTMP/C3_un_Mod.pdb

Chain information for C3_un_Mod.pdb #70  
---  
Chain | Description  
C3 | No description available  
  

> select #1/C4

530 atoms, 539 bonds, 73 residues, 1 model selected  

> save chainsTMP/C4_un.pdb format pdb models #1/C4 selectedOnly true

> open chainsTMP/C4_un_Mod.pdb

Chain information for C4_un_Mod.pdb #71  
---  
Chain | Description  
C4 | No description available  
  

> select #1/C5

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C5_un.pdb format pdb models #1/C5 selectedOnly true

> open chainsTMP/C5_un_Mod.pdb

Chain information for C5_un_Mod.pdb #72  
---  
Chain | Description  
C5 | No description available  
  

> select #1/C6

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C6_un.pdb format pdb models #1/C6 selectedOnly true

> open chainsTMP/C6_un_Mod.pdb

Chain information for C6_un_Mod.pdb #73  
---  
Chain | Description  
C6 | No description available  
  

> select #1/C7

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C7_un.pdb format pdb models #1/C7 selectedOnly true

> open chainsTMP/C7_un_Mod.pdb

Chain information for C7_un_Mod.pdb #74  
---  
Chain | Description  
C7 | No description available  
  

> select #1/C8

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C8_un.pdb format pdb models #1/C8 selectedOnly true

> open chainsTMP/C8_un_Mod.pdb

Chain information for C8_un_Mod.pdb #75  
---  
Chain | Description  
C8 | No description available  
  

> select #1/C9

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C9_un.pdb format pdb models #1/C9 selectedOnly true

> open chainsTMP/C9_un_Mod.pdb

Chain information for C9_un_Mod.pdb #76  
---  
Chain | Description  
C9 | No description available  
  

> select #1/D

1695 atoms, 1727 bonds, 1 pseudobond, 214 residues, 2 models selected  

> save chainsTMP/D_u.pdb format pdb models #1/D selectedOnly true

> open chainsTMP/D_u_Mod.pdb

Chain information for D_u_Mod.pdb #77  
---  
Chain | Description  
D | No description available  
  

> select #1/D6

437 atoms, 447 bonds, 1 pseudobond, 54 residues, 2 models selected  

> save chainsTMP/D6_un.pdb format pdb models #1/D6 selectedOnly true

> open chainsTMP/D6_un_Mod.pdb

Chain information for D6_un_Mod.pdb #78  
---  
Chain | Description  
D6 | No description available  
  

> select #1/E

4072 atoms, 4145 bonds, 2 pseudobonds, 526 residues, 2 models selected  

> save chainsTMP/E_u.pdb format pdb models #1/E selectedOnly true

> open chainsTMP/E_u_Mod.pdb

Chain information for E_u_Mod.pdb #79  
---  
Chain | Description  
E | No description available  
  

> select #1/E1

608 atoms, 625 bonds, 1 pseudobond, 80 residues, 2 models selected  

> save chainsTMP/E1_un.pdb format pdb models #1/E1 selectedOnly true

> open chainsTMP/E1_un_Mod.pdb

Chain information for E1_un_Mod.pdb #80  
---  
Chain | Description  
E1 | No description available  
  

> select #1/E4

1397 atoms, 1429 bonds, 169 residues, 1 model selected  

> save chainsTMP/E4_un.pdb format pdb models #1/E4 selectedOnly true

> open chainsTMP/E4_un_Mod.pdb

Chain information for E4_un_Mod.pdb #81  
---  
Chain | Description  
E4 | No description available  
  

> select #1/Ek

670 atoms, 695 bonds, 78 residues, 1 model selected  

> save chainsTMP/Ek_ul.pdb format pdb models #1/Ek selectedOnly true

> open chainsTMP/Ek_ul_Mod.pdb

Chain information for Ek_ul_Mod.pdb #82  
---  
Chain | Description  
Ek | No description available  
  

> select #1/Eq

772 atoms, 805 bonds, 84 residues, 1 model selected  

> save chainsTMP/Eq_ul.pdb format pdb models #1/Eq selectedOnly true

> open chainsTMP/Eq_ul_Mod.pdb

Chain information for Eq_ul_Mod.pdb #83  
---  
Chain | Description  
Eq | No description available  
  

> select #1/Es

1117 atoms, 1156 bonds, 135 residues, 1 model selected  

> save chainsTMP/Es_ul.pdb format pdb models #1/Es selectedOnly true

> open chainsTMP/Es_ul_Mod.pdb

Chain information for Es_ul_Mod.pdb #84  
---  
Chain | Description  
Es | No description available  
  

> select #1/Ev

3194 atoms, 3290 bonds, 384 residues, 1 model selected  

> save chainsTMP/Ev_ul.pdb format pdb models #1/Ev selectedOnly true

> open chainsTMP/Ev_ul_Mod.pdb

Chain information for Ev_ul_Mod.pdb #85  
---  
Chain | Description  
Ev | No description available  
  

> select #1/F9

595 atoms, 621 bonds, 67 residues, 1 model selected  

> save chainsTMP/F9_un.pdb format pdb models #1/F9 selectedOnly true

> open chainsTMP/F9_un_Mod.pdb

Chain information for F9_un_Mod.pdb #86  
---  
Chain | Description  
F9 | No description available  
  

> select #1/FF

596 atoms, 618 bonds, 1 pseudobond, 72 residues, 2 models selected  

> save chainsTMP/FF_uu.pdb format pdb models #1/FF selectedOnly true

> open chainsTMP/FF_uu_Mod.pdb

Chain information for FF_uu_Mod.pdb #87  
---  
Chain | Description  
FF | No description available  
  

> select #1/FH

1138 atoms, 1176 bonds, 140 residues, 1 model selected  

> save chainsTMP/FH_uu.pdb format pdb models #1/FH selectedOnly true

> open chainsTMP/FH_uu_Mod.pdb

Chain information for FH_uu_Mod.pdb #88  
---  
Chain | Description  
FH | No description available  
  

> select #1/FL

1998 atoms, 2068 bonds, 233 residues, 1 model selected  

> save chainsTMP/FL_uu.pdb format pdb models #1/FL selectedOnly true

> open chainsTMP/FL_uu_Mod.pdb

Chain information for FL_uu_Mod.pdb #89  
---  
Chain | Description  
FL | No description available  
  

> select #1/FO

1174 atoms, 1201 bonds, 148 residues, 1 model selected  

> save chainsTMP/FO_uu.pdb format pdb models #1/FO selectedOnly true

> open chainsTMP/FO_uu_Mod.pdb

Chain information for FO_uu_Mod.pdb #90  
---  
Chain | Description  
FO | No description available  
  

> select #1/Fy

480 atoms, 491 bonds, 58 residues, 1 model selected  

> save chainsTMP/Fy_ul.pdb format pdb models #1/Fy selectedOnly true

> open chainsTMP/Fy_ul_Mod.pdb

Chain information for Fy_ul_Mod.pdb #91  
---  
Chain | Description  
Fy | No description available  
  

> select #1/Fz

402 atoms, 412 bonds, 48 residues, 1 model selected  

> save chainsTMP/Fz_ul.pdb format pdb models #1/Fz selectedOnly true

> open chainsTMP/Fz_ul_Mod.pdb

Chain information for Fz_ul_Mod.pdb #92  
---  
Chain | Description  
Fz | No description available  
  

> select #1/GT

1489 atoms, 2104 bonds, 92 residues, 1 model selected  

> save chainsTMP/GT_uu.pdb format pdb models #1/GT selectedOnly true

> open chainsTMP/GT_uu_Mod.pdb

Chain information for GT_uu_Mod.pdb #93  
---  
Chain | Description  
GT | No description available  
  

> select #1/IE

1375 atoms, 1402 bonds, 1 pseudobond, 175 residues, 2 models selected  

> save chainsTMP/IE_uu.pdb format pdb models #1/IE selectedOnly true

> open chainsTMP/IE_uu_Mod.pdb

Chain information for IE_uu_Mod.pdb #94  
---  
Chain | Description  
IE | No description available  
  

> select #1/IY

2336 atoms, 2377 bonds, 294 residues, 1 model selected  

> save chainsTMP/IY_uu.pdb format pdb models #1/IY selectedOnly true

> open chainsTMP/IY_uu_Mod.pdb

Chain information for IY_uu_Mod.pdb #95  
---  
Chain | Description  
IY | No description available  
  

> select #1/JC

1254 atoms, 1276 bonds, 162 residues, 1 model selected  

> save chainsTMP/JC_uu.pdb format pdb models #1/JC selectedOnly true

> open chainsTMP/JC_uu_Mod.pdb

Chain information for JC_uu_Mod.pdb #96  
---  
Chain | Description  
JC | No description available  
  

> select #1/a

799 atoms, 822 bonds, 94 residues, 1 model selected  

> save chainsTMP/a_l.pdb format pdb models #1/a selectedOnly true

> open chainsTMP/a_l_Mod.pdb

Chain information for a_l_Mod.pdb #97  
---  
Chain | Description  
a | No description available  
  

> combine #2-97 close true modelId #2 name fixedModel

Computing secondary structure  
[Repeated 95 time(s)]

> hide #!1 models

> save "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV1.cif"
> models #2

Not saving entity_poly_seq for non-authoritative sequences  

> addh #2 hbond false

Summary of feedback from adding hydrogens to fixedModel #2  
---  
warnings | C-terminal fixedModel #2/GT SER 97 O does not look like carboxylate oxygen; cannot complete teminus  
Unknown hybridization for atoms (S4, S1, S3, S2) of residue type SF4; not
adding hydrogens to them  
Unknown hybridization for atoms (S4, S1, S3, S2) of residue type F3S; not
adding hydrogens to them  
notes | No usable SEQRES records for fixedModel (#2) chain AG; guessing termini instead  
No usable SEQRES records for fixedModel (#2) chain Ar; guessing termini
instead  
No usable SEQRES records for fixedModel (#2) chain I0; guessing termini
instead  
No usable SEQRES records for fixedModel (#2) chain Il; guessing termini
instead  
No usable SEQRES records for fixedModel (#2) chain Ix; guessing termini
instead  
86 messages similar to the above omitted  
Chain-initial residues that are actual N termini: fixedModel #2/AG PHE 18,
fixedModel #2/Ar LEU 23, fixedModel #2/I0 SER 160, fixedModel #2/Il TYR 26,
fixedModel #2/Ix ASP 152, fixedModel #2/Iy THR 22, fixedModel #2/J6 THR 2,
fixedModel #2/JI PRO 11, fixedModel #2/JJ MET 1, fixedModel #2/JN ALA 2,
fixedModel #2/Jw VAL 21, fixedModel #2/Jx LYS 11, fixedModel #2/K5 ALA 14,
fixedModel #2/KI THR 26, fixedModel #2/Ke ALA 44, fixedModel #2/Kp PRO 53,
fixedModel #2/Ks GLU 4, fixedModel #2/L3 VAL 52, fixedModel #2/LG TRP 20,
fixedModel #2/LO TYR 37, fixedModel #2/LR SER 78, fixedModel #2/LY PRO 182,
fixedModel #2/M PRO 2, fixedModel #2/Mg ILE 36, fixedModel #2/Mq SER 34,
fixedModel #2/Mr THR 38, fixedModel #2/NF LYS 30, fixedModel #2/NM TYR 82,
fixedModel #2/Np MET 1, fixedModel #2/TB MET 18, fixedModel #2/Y MET 1,
fixedModel #2/t0 THR 38, fixedModel #2/t1 THR 2, fixedModel #2/t2 TYR 37,
fixedModel #2/t3 PHE 18, fixedModel #2/t4 LEU 23, fixedModel #2/t5 THR 26,
fixedModel #2/t6 MET 1, fixedModel #2/t7 MET 1, fixedModel #2/t8 VAL 21,
fixedModel #2/t9 ASP 152, fixedModel #2/ta MET 1, fixedModel #2/tb SER 160,
fixedModel #2/tc THR 22, fixedModel #2/td TYR 26, fixedModel #2/te GLU 4,
fixedModel #2/tf ALA 2, fixedModel #2/tg PRO 182, fixedModel #2/R MET 1,
fixedModel #2/A ALA 34, fixedModel #2/A0 PRO 204, fixedModel #2/AU LYS 35,
fixedModel #2/Ab GLU 206, fixedModel #2/Aj LYS 208, fixedModel #2/Aq LYS 25,
fixedModel #2/B ALA 23, fixedModel #2/BI ALA 23, fixedModel #2/BK THR 37,
fixedModel #2/BP GLY 22, fixedModel #2/C SER 85, fixedModel #2/C0 ILE 33,
fixedModel #2/C1 ILE 33, fixedModel #2/C2 ILE 33, fixedModel #2/C3 ILE 33,
fixedModel #2/C4 SER 34, fixedModel #2/C5 ILE 33, fixedModel #2/C6 ILE 33,
fixedModel #2/C7 ILE 33, fixedModel #2/C8 ILE 33, fixedModel #2/C9 ILE 33,
fixedModel #2/D TYR 18, fixedModel #2/D6 VAL 7, fixedModel #2/E PHE 33,
fixedModel #2/E1 LEU 51, fixedModel #2/E4 GLN 35, fixedModel #2/Ek ASN 26,
fixedModel #2/Eq ASN 62, fixedModel #2/Es VAL 2, fixedModel #2/Ev GLY 3,
fixedModel #2/F9 HIS 37, fixedModel #2/FF HIS 98, fixedModel #2/FH VAL 18,
fixedModel #2/FL MET 1, fixedModel #2/FO PHE 12, fixedModel #2/Fy PRO 60,
fixedModel #2/Fz VAL 58, fixedModel #2/GT ALA 6, fixedModel #2/IE LYS 26,
fixedModel #2/IY SER 2, fixedModel #2/JC GLU 22, fixedModel #2/a TYR 3  
Chain-initial residues that are not actual N termini: fixedModel #2/JI GLU
259, fixedModel #2/K5 LYS 143, fixedModel #2/K5 ARG 299, fixedModel #2/K5 LYS
338, fixedModel #2/K5 ILE 361, fixedModel #2/K5 GLU 490, fixedModel #2/K5 MET
567, fixedModel #2/L3 TYR 94, fixedModel #2/L3 VAL 198, fixedModel #2/L3 VAL
312, fixedModel #2/NF ARG 189, fixedModel #2/AU GLN 151, fixedModel #2/AU GLN
436, fixedModel #2/Ab THR 521, fixedModel #2/BK GLN 151, fixedModel #2/BK VAL
437, fixedModel #2/D ILE 234, fixedModel #2/D6 VAL 63, fixedModel #2/E GLN
151, fixedModel #2/E GLN 438, fixedModel #2/E1 ASP 217, fixedModel #2/FF MET
124, fixedModel #2/IE VAL 199  
Chain-final residues that are actual C termini: fixedModel #2/R HIS 62,
fixedModel #2/A PRO 357, fixedModel #2/A0 LYS 685, fixedModel #2/AU VAL 574,
fixedModel #2/Ab ARG 690, fixedModel #2/Aj HIS 690, fixedModel #2/Aq GLN 187,
fixedModel #2/B LYS 160, fixedModel #2/BI GLN 187, fixedModel #2/BK VAL 574,
fixedModel #2/BP GLN 187, fixedModel #2/C MET 349, fixedModel #2/C0 SER 106,
fixedModel #2/C1 SER 106, fixedModel #2/C2 SER 106, fixedModel #2/C3 SER 106,
fixedModel #2/C4 SER 106, fixedModel #2/C5 SER 106, fixedModel #2/C6 SER 106,
fixedModel #2/C7 SER 106, fixedModel #2/C8 SER 106, fixedModel #2/C9 SER 106,
fixedModel #2/D VAL 258, fixedModel #2/D6 THR 70, fixedModel #2/E GLY 575,
fixedModel #2/E1 GLY 239, fixedModel #2/E4 GLY 203, fixedModel #2/Ek SER 103,
fixedModel #2/Eq TYR 145, fixedModel #2/Es HIS 136, fixedModel #2/Ev ALA 386,
fixedModel #2/F9 GLN 103, fixedModel #2/FF PRO 174, fixedModel #2/FH VAL 157,
fixedModel #2/FL GLY 233, fixedModel #2/FO ALA 159, fixedModel #2/Fy ALA 117,
fixedModel #2/Fz VAL 105, fixedModel #2/GT SER 97, fixedModel #2/IE GLY 204,
fixedModel #2/IY ASN 295, fixedModel #2/JC GLU 183, fixedModel #2/a GLN 96  
Chain-final residues that are not actual C termini: fixedModel #2/AG SER 196,
fixedModel #2/Ar TRP 118, fixedModel #2/I0 LYS 383, fixedModel #2/Il GLU 104,
fixedModel #2/Ix ILE 279, fixedModel #2/Iy GLN 115, fixedModel #2/J6 PHE 199,
fixedModel #2/JI LYS 491, fixedModel #2/JI PHE 252, fixedModel #2/JJ ILE 549,
fixedModel #2/JN VAL 108, fixedModel #2/Jw PHE 144, fixedModel #2/Jx ASP 124,
fixedModel #2/K5 PRO 602, fixedModel #2/K5 ILE 138, fixedModel #2/K5 GLU 268,
fixedModel #2/K5 LEU 311, fixedModel #2/K5 VAL 354, fixedModel #2/K5 ALA 484,
fixedModel #2/K5 ARG 546, fixedModel #2/KI GLU 225, fixedModel #2/Ke LEU 138,
fixedModel #2/Kp GLU 224, fixedModel #2/Ks ALA 156, fixedModel #2/L3 ARG 325,
fixedModel #2/L3 LEU 84, fixedModel #2/L3 GLY 117, fixedModel #2/L3 HIS 283,
fixedModel #2/LG SER 123, fixedModel #2/LO LYS 342, fixedModel #2/LR GLY 148,
fixedModel #2/LY ALA 345, fixedModel #2/M PHE 103, fixedModel #2/Mg ALA 250,
fixedModel #2/Mq LYS 90, fixedModel #2/Mr LEU 147, fixedModel #2/NF SER 246,
fixedModel #2/NF LEU 183, fixedModel #2/NM MET 144, fixedModel #2/Np VAL 283,
fixedModel #2/TB THR 81, fixedModel #2/Y ILE 210, fixedModel #2/t0 LEU 147,
fixedModel #2/t1 PHE 199, fixedModel #2/t2 LYS 342, fixedModel #2/t3 SER 196,
fixedModel #2/t4 TRP 118, fixedModel #2/t5 GLU 225, fixedModel #2/t6 ILE 549,
fixedModel #2/t7 VAL 283, fixedModel #2/t8 PHE 144, fixedModel #2/t9 ILE 279,
fixedModel #2/ta ILE 210, fixedModel #2/tb LYS 383, fixedModel #2/tc GLN 115,
fixedModel #2/td GLU 104, fixedModel #2/te ALA 156, fixedModel #2/tf VAL 108,
fixedModel #2/tg ALA 345, fixedModel #2/AU LEU 139, fixedModel #2/AU ASP 430,
fixedModel #2/Ab VAL 515, fixedModel #2/BK GLY 138, fixedModel #2/BK ASP 430,
fixedModel #2/D LYS 206, fixedModel #2/D6 LEU 52, fixedModel #2/E LEU 139,
fixedModel #2/E ALA 429, fixedModel #2/E1 GLU 123, fixedModel #2/FF TYR 118,
fixedModel #2/IE VAL 194  
Adding 'H' to fixedModel #2/JI GLU 259  
Adding 'H' to fixedModel #2/K5 LYS 143  
Adding 'H' to fixedModel #2/K5 ARG 299  
Adding 'H' to fixedModel #2/K5 LYS 338  
Adding 'H' to fixedModel #2/K5 ILE 361  
18 messages similar to the above omitted  
fixedModel #2/AG SER 196 is not terminus, removing H atom from 'C'  
fixedModel #2/Ar TRP 118 is not terminus, removing H atom from 'C'  
fixedModel #2/I0 LYS 383 is not terminus, removing H atom from 'C'  
fixedModel #2/Il GLU 104 is not terminus, removing H atom from 'C'  
fixedModel #2/Ix ILE 279 is not terminus, removing H atom from 'C'  
43 messages similar to the above omitted  
135317 hydrogens added  
  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
Loading residue template for 3PE from internal database  
Loading residue template for ATP from internal database  
Loading residue template for FAD from internal database  
Loading residue template for LPP from internal database  
Loading residue template for PC1 from internal database  

Chain HM, residue 1 specifies more than one residue! The simulation can still
run, but this will probably cause problems later if not rectified by
renumbering.  

> delete #2/GT:27@H*

> select clear

> select up

33 atoms, 38 bonds, 1 residue, 1 model selected  

> select up

33 atoms, 38 bonds, 1 residue, 1 model selected  

> ui mousemode right "translate selected atoms"

Deleted the following atoms from residue LEU GT28: HN2, HC8, HC9, HC13, CB,
HC2, CG, CD1, CD2, C, HC10, HC5, HC4, HC14, HC11, HC6, N, HC7, HC3, HN1, HC,
HC1, CA, O, HC12  

> delete #3@H*

> delete #2@H*

> select up

8 atoms, 7 bonds, 1 residue, 1 model selected  

> bond #2/GT:27@C #2/GT:28@N

Created 3 bonds  

> bond #2/GT:28@C #2/GT:29@N

Created 2 bonds  

> bond #2/GT:26@C #2/GT:27@N

Created 5 bonds  

> addh #2 hbond false

Summary of feedback from adding hydrogens to fixedModel #2.2  
---  
warnings | C-terminal fixedModel #2.2/GT SER 97 O does not look like carboxylate oxygen; cannot complete teminus  
Unknown hybridization for atoms (S4, S1, S3, S2) of residue type SF4; not
adding hydrogens to them  
Unknown hybridization for atoms (S4, S1, S3, S2) of residue type F3S; not
adding hydrogens to them  
notes | No usable SEQRES records for fixedModel (#2.2) chain AG; guessing termini instead  
No usable SEQRES records for fixedModel (#2.2) chain Ar; guessing termini
instead  
No usable SEQRES records for fixedModel (#2.2) chain I0; guessing termini
instead  
No usable SEQRES records for fixedModel (#2.2) chain Il; guessing termini
instead  
No usable SEQRES records for fixedModel (#2.2) chain Ix; guessing termini
instead  
86 messages similar to the above omitted  
Chain-initial residues that are actual N termini: fixedModel #2.2/AG PHE 18,
fixedModel #2.2/Ar LEU 23, fixedModel #2.2/I0 SER 160, fixedModel #2.2/Il TYR
26, fixedModel #2.2/Ix ASP 152, fixedModel #2.2/Iy THR 22, fixedModel #2.2/J6
THR 2, fixedModel #2.2/JI PRO 11, fixedModel #2.2/JJ MET 1, fixedModel #2.2/JN
ALA 2, fixedModel #2.2/Jw VAL 21, fixedModel #2.2/Jx LYS 11, fixedModel
#2.2/K5 ALA 14, fixedModel #2.2/KI THR 26, fixedModel #2.2/Ke ALA 44,
fixedModel #2.2/Kp PRO 53, fixedModel #2.2/Ks GLU 4, fixedModel #2.2/L3 VAL
52, fixedModel #2.2/LG TRP 20, fixedModel #2.2/LO TYR 37, fixedModel #2.2/LR
SER 78, fixedModel #2.2/LY PRO 182, fixedModel #2.2/M PRO 2, fixedModel
#2.2/Mg ILE 36, fixedModel #2.2/Mq SER 34, fixedModel #2.2/Mr THR 38,
fixedModel #2.2/NF LYS 30, fixedModel #2.2/NM TYR 82, fixedModel #2.2/Np MET
1, fixedModel #2.2/TB MET 18, fixedModel #2.2/Y MET 1, fixedModel #2.2/t0 THR
38, fixedModel #2.2/t1 THR 2, fixedModel #2.2/t2 TYR 37, fixedModel #2.2/t3
PHE 18, fixedModel #2.2/t4 LEU 23, fixedModel #2.2/t5 THR 26, fixedModel
#2.2/t6 MET 1, fixedModel #2.2/t7 MET 1, fixedModel #2.2/t8 VAL 21, fixedModel
#2.2/t9 ASP 152, fixedModel #2.2/ta MET 1, fixedModel #2.2/tb SER 160,
fixedModel #2.2/tc THR 22, fixedModel #2.2/td TYR 26, fixedModel #2.2/te GLU
4, fixedModel #2.2/tf ALA 2, fixedModel #2.2/tg PRO 182, fixedModel #2.2/R MET
1, fixedModel #2.2/A ALA 34, fixedModel #2.2/A0 PRO 204, fixedModel #2.2/AU
LYS 35, fixedModel #2.2/Ab GLU 206, fixedModel #2.2/Aj LYS 208, fixedModel
#2.2/Aq LYS 25, fixedModel #2.2/B ALA 23, fixedModel #2.2/BI ALA 23,
fixedModel #2.2/BK THR 37, fixedModel #2.2/BP GLY 22, fixedModel #2.2/C SER
85, fixedModel #2.2/C0 ILE 33, fixedModel #2.2/C1 ILE 33, fixedModel #2.2/C2
ILE 33, fixedModel #2.2/C3 ILE 33, fixedModel #2.2/C4 SER 34, fixedModel
#2.2/C5 ILE 33, fixedModel #2.2/C6 ILE 33, fixedModel #2.2/C7 ILE 33,
fixedModel #2.2/C8 ILE 33, fixedModel #2.2/C9 ILE 33, fixedModel #2.2/D TYR
18, fixedModel #2.2/D6 VAL 7, fixedModel #2.2/E PHE 33, fixedModel #2.2/E1 LEU
51, fixedModel #2.2/E4 GLN 35, fixedModel #2.2/Ek ASN 26, fixedModel #2.2/Eq
ASN 62, fixedModel #2.2/Es VAL 2, fixedModel #2.2/Ev GLY 3, fixedModel #2.2/F9
HIS 37, fixedModel #2.2/FF HIS 98, fixedModel #2.2/FH VAL 18, fixedModel
#2.2/FL MET 1, fixedModel #2.2/FO PHE 12, fixedModel #2.2/Fy PRO 60,
fixedModel #2.2/Fz VAL 58, fixedModel #2.2/GT ALA 6, fixedModel #2.2/IE LYS
26, fixedModel #2.2/IY SER 2, fixedModel #2.2/JC GLU 22, fixedModel #2.2/a TYR
3  
Chain-initial residues that are not actual N termini: fixedModel #2.2/JI GLU
259, fixedModel #2.2/K5 LYS 143, fixedModel #2.2/K5 ARG 299, fixedModel
#2.2/K5 LYS 338, fixedModel #2.2/K5 ILE 361, fixedModel #2.2/K5 GLU 490,
fixedModel #2.2/K5 MET 567, fixedModel #2.2/L3 TYR 94, fixedModel #2.2/L3 VAL
198, fixedModel #2.2/L3 VAL 312, fixedModel #2.2/NF ARG 189, fixedModel
#2.2/AU GLN 151, fixedModel #2.2/AU GLN 436, fixedModel #2.2/Ab THR 521,
fixedModel #2.2/BK GLN 151, fixedModel #2.2/BK VAL 437, fixedModel #2.2/D ILE
234, fixedModel #2.2/D6 VAL 63, fixedModel #2.2/E GLN 151, fixedModel #2.2/E
GLN 438, fixedModel #2.2/E1 ASP 217, fixedModel #2.2/FF MET 124, fixedModel
#2.2/IE VAL 199  
Chain-final residues that are actual C termini: fixedModel #2.2/R HIS 62,
fixedModel #2.2/A PRO 357, fixedModel #2.2/A0 LYS 685, fixedModel #2.2/AU VAL
574, fixedModel #2.2/Ab ARG 690, fixedModel #2.2/Aj HIS 690, fixedModel
#2.2/Aq GLN 187, fixedModel #2.2/B LYS 160, fixedModel #2.2/BI GLN 187,
fixedModel #2.2/BK VAL 574, fixedModel #2.2/BP GLN 187, fixedModel #2.2/C MET
349, fixedModel #2.2/C0 SER 106, fixedModel #2.2/C1 SER 106, fixedModel
#2.2/C2 SER 106, fixedModel #2.2/C3 SER 106, fixedModel #2.2/C4 SER 106,
fixedModel #2.2/C5 SER 106, fixedModel #2.2/C6 SER 106, fixedModel #2.2/C7 SER
106, fixedModel #2.2/C8 SER 106, fixedModel #2.2/C9 SER 106, fixedModel #2.2/D
VAL 258, fixedModel #2.2/D6 THR 70, fixedModel #2.2/E GLY 575, fixedModel
#2.2/E1 GLY 239, fixedModel #2.2/E4 GLY 203, fixedModel #2.2/Ek SER 103,
fixedModel #2.2/Eq TYR 145, fixedModel #2.2/Es HIS 136, fixedModel #2.2/Ev ALA
386, fixedModel #2.2/F9 GLN 103, fixedModel #2.2/FF PRO 174, fixedModel
#2.2/FH VAL 157, fixedModel #2.2/FL GLY 233, fixedModel #2.2/FO ALA 159,
fixedModel #2.2/Fy ALA 117, fixedModel #2.2/Fz VAL 105, fixedModel #2.2/GT SER
97, fixedModel #2.2/IE GLY 204, fixedModel #2.2/IY ASN 295, fixedModel #2.2/JC
GLU 183, fixedModel #2.2/a GLN 96  
Chain-final residues that are not actual C termini: fixedModel #2.2/AG SER
196, fixedModel #2.2/Ar TRP 118, fixedModel #2.2/I0 LYS 383, fixedModel
#2.2/Il GLU 104, fixedModel #2.2/Ix ILE 279, fixedModel #2.2/Iy GLN 115,
fixedModel #2.2/J6 PHE 199, fixedModel #2.2/JI LYS 491, fixedModel #2.2/JI PHE
252, fixedModel #2.2/JJ ILE 549, fixedModel #2.2/JN VAL 108, fixedModel
#2.2/Jw PHE 144, fixedModel #2.2/Jx ASP 124, fixedModel #2.2/K5 PRO 602,
fixedModel #2.2/K5 ILE 138, fixedModel #2.2/K5 GLU 268, fixedModel #2.2/K5 LEU
311, fixedModel #2.2/K5 VAL 354, fixedModel #2.2/K5 ALA 484, fixedModel
#2.2/K5 ARG 546, fixedModel #2.2/KI GLU 225, fixedModel #2.2/Ke LEU 138,
fixedModel #2.2/Kp GLU 224, fixedModel #2.2/Ks ALA 156, fixedModel #2.2/L3 ARG
325, fixedModel #2.2/L3 LEU 84, fixedModel #2.2/L3 GLY 117, fixedModel #2.2/L3
HIS 283, fixedModel #2.2/LG SER 123, fixedModel #2.2/LO LYS 342, fixedModel
#2.2/LR GLY 148, fixedModel #2.2/LY ALA 345, fixedModel #2.2/M PHE 103,
fixedModel #2.2/Mg ALA 250, fixedModel #2.2/Mq LYS 90, fixedModel #2.2/Mr LEU
147, fixedModel #2.2/NF SER 246, fixedModel #2.2/NF LEU 183, fixedModel
#2.2/NM MET 144, fixedModel #2.2/Np VAL 283, fixedModel #2.2/TB THR 81,
fixedModel #2.2/Y ILE 210, fixedModel #2.2/t0 LEU 147, fixedModel #2.2/t1 PHE
199, fixedModel #2.2/t2 LYS 342, fixedModel #2.2/t3 SER 196, fixedModel
#2.2/t4 TRP 118, fixedModel #2.2/t5 GLU 225, fixedModel #2.2/t6 ILE 549,
fixedModel #2.2/t7 VAL 283, fixedModel #2.2/t8 PHE 144, fixedModel #2.2/t9 ILE
279, fixedModel #2.2/ta ILE 210, fixedModel #2.2/tb LYS 383, fixedModel
#2.2/tc GLN 115, fixedModel #2.2/td GLU 104, fixedModel #2.2/te ALA 156,
fixedModel #2.2/tf VAL 108, fixedModel #2.2/tg ALA 345, fixedModel #2.2/AU LEU
139, fixedModel #2.2/AU ASP 430, fixedModel #2.2/Ab VAL 515, fixedModel
#2.2/BK GLY 138, fixedModel #2.2/BK ASP 430, fixedModel #2.2/D LYS 206,
fixedModel #2.2/D6 LEU 52, fixedModel #2.2/E LEU 139, fixedModel #2.2/E ALA
429, fixedModel #2.2/E1 GLU 123, fixedModel #2.2/FF TYR 118, fixedModel
#2.2/IE VAL 194  
Adding 'H' to fixedModel #2.2/JI GLU 259  
Adding 'H' to fixedModel #2.2/K5 LYS 143  
Adding 'H' to fixedModel #2.2/K5 ARG 299  
Adding 'H' to fixedModel #2.2/K5 LYS 338  
Adding 'H' to fixedModel #2.2/K5 ILE 361  
18 messages similar to the above omitted  
fixedModel #2.2/AG SER 196 is not terminus, removing H atom from 'C'  
fixedModel #2.2/Ar TRP 118 is not terminus, removing H atom from 'C'  
fixedModel #2.2/I0 LYS 383 is not terminus, removing H atom from 'C'  
fixedModel #2.2/Il GLU 104 is not terminus, removing H atom from 'C'  
fixedModel #2.2/Ix ILE 279 is not terminus, removing H atom from 'C'  
43 messages similar to the above omitted  
135304 hydrogens added  
  

Chain HM, residue 1 specifies more than one residue! The simulation can still
run, but this will probably cause problems later if not rectified by
renumbering.  

Fetching CCD LEU_LEO2 from http://ligand-
expo.rcsb.org/reports/L/LEU_LEO2/LEU_LEO2.cif  
Fetching CCD LEU_LFZW from http://ligand-
expo.rcsb.org/reports/L/LEU_LFZW/LEU_LFZW.cif  
Deleted the following atoms from residue LEU GT55: HC3, HN1, HN2, N, HC2, HC1,
HC11, HC10, HC4, HC7, HC, HC9, CA, CG, C, O, HC6, HC12, HC13, HC14, CB, CD1,
CD2, HC8, HC5  
Deleted the following atoms from residue LEU GT43: HC7, HC4, HN1, N, HC3, HN2,
HC, HC12, HC10, HC8, CD2, CA, CG, HC2, HC5, HC1, C, HC14, HC13, HC6, HC9,
HC11, O, CB, CD1  
Deleted the following atoms from residue LEU GT33: HC8, HC4, N, C, CB, HC3,
HC6, HC13, HC14, HC12, CD2, HC2, HC1, HC, O, CA, HC10, HN1, HC5, HC11, HC9,
HN2, HC7, CG, CD1  
Deleted the following atoms from residue LEU GT24: HC7, HC11, HC12, HC, HC3,
C, O, CD2, CB, HC2, CG, CD1, HC6, HN2, N, HC14, HC10, HC4, HC13, HC1, HC8,
HC9, HC5, CA, HN1  

> info residues #2/GT

residue id #2.2/GT:6 name ALA index 0  
residue id #2.2/GT:7 name PHE index 1  
residue id #2.2/GT:8 name HIS index 2  
residue id #2.2/GT:9 name ASP index 3  
residue id #2.2/GT:10 name VAL index 4  
residue id #2.2/GT:11 name SER index 5  
residue id #2.2/GT:12 name THR index 6  
residue id #2.2/GT:13 name ASP index 7  
residue id #2.2/GT:14 name ALA index 8  
residue id #2.2/GT:15 name ILE index 9  
residue id #2.2/GT:16 name ARG index 10  
residue id #2.2/GT:17 name GLN index 11  
residue id #2.2/GT:18 name MET index 12  
residue id #2.2/GT:19 name GLN index 13  
residue id #2.2/GT:20 name ALA index 14  
residue id #2.2/GT:21 name SER index 15  
residue id #2.2/GT:22 name GLU index 16  
residue id #2.2/GT:23 name ALA index 17  
residue id #2.2/GT:24 name LEU index 18  
residue id #2.2/GT:25 name GLN index 19  
residue id #2.2/GT:26 name LYS index 20  
residue id #2.2/GT:27 name HIS index 21  
residue id #2.2/GT:28 name LEU index 22  
residue id #2.2/GT:29 name GLU index 23  
residue id #2.2/GT:30 name ASN index 24  
residue id #2.2/GT:31 name ALA index 25  
residue id #2.2/GT:32 name GLN index 26  
residue id #2.2/GT:33 name LEU index 27  
residue id #2.2/GT:34 name ALA index 28  
residue id #2.2/GT:35 name HIS index 29  
residue id #2.2/GT:36 name ARG index 30  
residue id #2.2/GT:37 name VAL index 31  
residue id #2.2/GT:38 name CYS index 32  
residue id #2.2/GT:39 name VAL index 33  
residue id #2.2/GT:40 name ALA index 34  
residue id #2.2/GT:41 name LYS index 35  
residue id #2.2/GT:42 name ALA index 36  
residue id #2.2/GT:43 name LEU index 37  
residue id #2.2/GT:44 name LYS index 38  
residue id #2.2/GT:45 name ALA index 39  
residue id #2.2/GT:46 name ASP index 40  
residue id #2.2/GT:47 name GLU index 41  
residue id #2.2/GT:48 name PRO index 42  
residue id #2.2/GT:49 name PRO index 43  
residue id #2.2/GT:50 name VAL index 44  
residue id #2.2/GT:51 name GLU index 45  
residue id #2.2/GT:52 name LYS index 46  
residue id #2.2/GT:53 name CYS index 47  
residue id #2.2/GT:54 name ALA index 48  
residue id #2.2/GT:55 name LEU index 49  
residue id #2.2/GT:56 name THR index 50  
residue id #2.2/GT:57 name TRP index 51  
residue id #2.2/GT:58 name GLY index 52  
residue id #2.2/GT:59 name GLU index 53  
residue id #2.2/GT:60 name VAL index 54  
residue id #2.2/GT:61 name VAL index 55  
residue id #2.2/GT:62 name MET index 56  
residue id #2.2/GT:63 name ARG index 57  
residue id #2.2/GT:64 name TYR index 58  
residue id #2.2/GT:65 name ASN index 59  
residue id #2.2/GT:66 name GLN index 60  
residue id #2.2/GT:67 name TRP index 61  
residue id #2.2/GT:68 name SER index 62  
residue id #2.2/GT:69 name GLU index 63  
residue id #2.2/GT:70 name TYR index 64  
residue id #2.2/GT:71 name ARG index 65  
residue id #2.2/GT:72 name PRO index 66  
residue id #2.2/GT:73 name ALA index 67  
residue id #2.2/GT:74 name PHE index 68  
residue id #2.2/GT:75 name HIS index 69  
residue id #2.2/GT:76 name ASP index 70  
residue id #2.2/GT:77 name SER index 71  
residue id #2.2/GT:78 name ASP index 72  
residue id #2.2/GT:79 name ALA index 73  
residue id #2.2/GT:80 name GLN index 74  
residue id #2.2/GT:81 name LYS index 75  
residue id #2.2/GT:82 name ARG index 76  
residue id #2.2/GT:83 name TYR index 77  
residue id #2.2/GT:84 name SER index 78  
residue id #2.2/GT:85 name LYS index 79  
residue id #2.2/GT:86 name TYR index 80  
residue id #2.2/GT:87 name TRP index 81  
residue id #2.2/GT:88 name THR index 82  
residue id #2.2/GT:89 name LYS index 83  
residue id #2.2/GT:90 name LYS index 84  
residue id #2.2/GT:91 name ARG index 85  
residue id #2.2/GT:92 name GLN index 86  
residue id #2.2/GT:93 name ALA index 87  
residue id #2.2/GT:94 name ALA index 88  
residue id #2.2/GT:95 name ASP index 89  
residue id #2.2/GT:96 name ASP index 90  
residue id #2.2/GT:97 name SER index 91  

> delete #2@H*

> bond #2.2/GT:6@C #2.2/GT:7@N

Created 5 bonds  

> bond #2.2/GT:7@C #2.2/GT:8@N

Created 5 bonds  

> bond #2.2/GT:8@C #2.2/GT:9@N

Created 5 bonds  

> bond #2.2/GT:9@C #2.2/GT:10@N

Created 5 bonds  

> bond #2.2/GT:10@C #2.2/GT:11@N

Created 5 bonds  

> bond #2.2/GT:11@C #2.2/GT:12@N

Created 5 bonds  

> bond #2.2/GT:12@C #2.2/GT:13@N

Created 5 bonds  

> bond #2.2/GT:13@C #2.2/GT:14@N

Created 5 bonds  

> bond #2.2/GT:14@C #2.2/GT:15@N

Created 5 bonds  

> bond #2.2/GT:15@C #2.2/GT:16@N

Created 5 bonds  

> bond #2.2/GT:16@C #2.2/GT:17@N

Created 5 bonds  

> bond #2.2/GT:17@C #2.2/GT:18@N

Created 5 bonds  

> bond #2.2/GT:18@C #2.2/GT:19@N

Created 5 bonds  

> bond #2.2/GT:19@C #2.2/GT:20@N

Created 5 bonds  

> bond #2.2/GT:20@C #2.2/GT:21@N

Created 5 bonds  

> bond #2.2/GT:21@C #2.2/GT:22@N

Created 5 bonds  

> bond #2.2/GT:22@C #2.2/GT:23@N

Created 5 bonds  

> bond #2.2/GT:23@C #2.2/GT:24@N

Created 3 bonds  

> bond #2.2/GT:24@C #2.2/GT:25@N

Created 2 bonds  

> bond #2.2/GT:25@C #2.2/GT:26@N

Created 5 bonds  

> bond #2.2/GT:26@C #2.2/GT:27@N

Created 0 bonds  

> bond #2.2/GT:27@C #2.2/GT:28@N

Created 0 bonds  

> bond #2.2/GT:28@C #2.2/GT:29@N

Created 0 bonds  

> bond #2.2/GT:29@C #2.2/GT:30@N

Created 5 bonds  

> bond #2.2/GT:30@C #2.2/GT:31@N

Created 5 bonds  

> bond #2.2/GT:31@C #2.2/GT:32@N

Created 5 bonds  

> bond #2.2/GT:32@C #2.2/GT:33@N

Created 3 bonds  

> bond #2.2/GT:33@C #2.2/GT:34@N

Created 2 bonds  

> bond #2.2/GT:34@C #2.2/GT:35@N

Created 5 bonds  

> bond #2.2/GT:35@C #2.2/GT:36@N

Created 5 bonds  

> bond #2.2/GT:36@C #2.2/GT:37@N

Created 5 bonds  

> bond #2.2/GT:37@C #2.2/GT:38@N

Created 5 bonds  

> bond #2.2/GT:38@C #2.2/GT:39@N

Created 5 bonds  

> bond #2.2/GT:39@C #2.2/GT:40@N

Created 5 bonds  

> bond #2.2/GT:40@C #2.2/GT:41@N

Created 5 bonds  

> bond #2.2/GT:41@C #2.2/GT:42@N

Created 5 bonds  

> bond #2.2/GT:42@C #2.2/GT:43@N

Created 3 bonds  

> bond #2.2/GT:43@C #2.2/GT:44@N

Created 2 bonds  

> bond #2.2/GT:44@C #2.2/GT:45@N

Created 5 bonds  

> bond #2.2/GT:45@C #2.2/GT:46@N

Created 5 bonds  

> bond #2.2/GT:46@C #2.2/GT:47@N

Created 5 bonds  

> bond #2.2/GT:47@C #2.2/GT:48@N

Created 5 bonds  

> bond #2.2/GT:48@C #2.2/GT:49@N

Created 5 bonds  

> bond #2.2/GT:49@C #2.2/GT:50@N

Created 5 bonds  

> bond #2.2/GT:50@C #2.2/GT:51@N

Created 5 bonds  

> bond #2.2/GT:51@C #2.2/GT:52@N

Created 5 bonds  

> bond #2.2/GT:52@C #2.2/GT:53@N

Created 5 bonds  

> bond #2.2/GT:53@C #2.2/GT:54@N

Created 5 bonds  

> bond #2.2/GT:54@C #2.2/GT:55@N

Created 3 bonds  

> bond #2.2/GT:55@C #2.2/GT:56@N

Created 2 bonds  

> bond #2.2/GT:56@C #2.2/GT:57@N

Created 5 bonds  

> bond #2.2/GT:57@C #2.2/GT:58@N

Created 5 bonds  

> bond #2.2/GT:58@C #2.2/GT:59@N

Created 5 bonds  

> bond #2.2/GT:59@C #2.2/GT:60@N

Created 5 bonds  

> bond #2.2/GT:60@C #2.2/GT:61@N

Created 5 bonds  

> bond #2.2/GT:61@C #2.2/GT:62@N

Created 5 bonds  

> bond #2.2/GT:62@C #2.2/GT:63@N

Created 5 bonds  

> bond #2.2/GT:63@C #2.2/GT:64@N

Created 5 bonds  

> bond #2.2/GT:64@C #2.2/GT:65@N

Created 5 bonds  

> bond #2.2/GT:65@C #2.2/GT:66@N

Created 5 bonds  

> bond #2.2/GT:66@C #2.2/GT:67@N

Created 5 bonds  

> bond #2.2/GT:67@C #2.2/GT:68@N

Created 5 bonds  

> bond #2.2/GT:68@C #2.2/GT:69@N

Created 5 bonds  

> bond #2.2/GT:69@C #2.2/GT:70@N

Created 5 bonds  

> bond #2.2/GT:70@C #2.2/GT:71@N

Created 5 bonds  

> bond #2.2/GT:71@C #2.2/GT:72@N

Created 5 bonds  

> bond #2.2/GT:72@C #2.2/GT:73@N

Created 5 bonds  

> bond #2.2/GT:73@C #2.2/GT:74@N

Created 2 bonds  

> bond #2.2/GT:74@C #2.2/GT:75@N

Created 2 bonds  

> bond #2.2/GT:75@C #2.2/GT:76@N

Created 5 bonds  

> bond #2.2/GT:76@C #2.2/GT:77@N

Created 5 bonds  

> bond #2.2/GT:77@C #2.2/GT:78@N

Created 5 bonds  

> bond #2.2/GT:78@C #2.2/GT:79@N

Created 5 bonds  

> bond #2.2/GT:79@C #2.2/GT:80@N

Created 5 bonds  

> bond #2.2/GT:80@C #2.2/GT:81@N

Created 5 bonds  

> bond #2.2/GT:81@C #2.2/GT:82@N

Created 5 bonds  

> bond #2.2/GT:82@C #2.2/GT:83@N

Created 5 bonds  

> bond #2.2/GT:83@C #2.2/GT:84@N

Created 5 bonds  

> bond #2.2/GT:84@C #2.2/GT:85@N

Created 5 bonds  

> bond #2.2/GT:85@C #2.2/GT:86@N

Created 5 bonds  

> bond #2.2/GT:86@C #2.2/GT:87@N

Created 5 bonds  

> bond #2.2/GT:87@C #2.2/GT:88@N

Created 5 bonds  

> bond #2.2/GT:88@C #2.2/GT:89@N

Created 5 bonds  

> bond #2.2/GT:89@C #2.2/GT:90@N

Created 5 bonds  

> bond #2.2/GT:90@C #2.2/GT:91@N

Created 5 bonds  

> bond #2.2/GT:91@C #2.2/GT:92@N

Created 5 bonds  

> bond #2.2/GT:92@C #2.2/GT:93@N

Created 5 bonds  

> bond #2.2/GT:93@C #2.2/GT:94@N

Created 5 bonds  

> bond #2.2/GT:94@C #2.2/GT:95@N

Created 5 bonds  

> bond #2.2/GT:95@C #2.2/GT:96@N

Created 5 bonds  

> bond #2.2/GT:96@C #2.2/GT:97@N

Created 5 bonds  

> addh #2 hbond false

Summary of feedback from adding hydrogens to fixedModel #2.2  
---  
warnings | C-terminal fixedModel #2.2/GT SER 97 O does not look like carboxylate oxygen; cannot complete teminus  
Unknown hybridization for atoms (S4, S1, S3, S2) of residue type SF4; not
adding hydrogens to them  
Unknown hybridization for atoms (S4, S1, S3, S2) of residue type F3S; not
adding hydrogens to them  
notes | No usable SEQRES records for fixedModel (#2.2) chain AG; guessing termini instead  
No usable SEQRES records for fixedModel (#2.2) chain Ar; guessing termini
instead  
No usable SEQRES records for fixedModel (#2.2) chain I0; guessing termini
instead  
No usable SEQRES records for fixedModel (#2.2) chain Il; guessing termini
instead  
No usable SEQRES records for fixedModel (#2.2) chain Ix; guessing termini
instead  
86 messages similar to the above omitted  
Chain-initial residues that are actual N termini: fixedModel #2.2/AG PHE 18,
fixedModel #2.2/Ar LEU 23, fixedModel #2.2/I0 SER 160, fixedModel #2.2/Il TYR
26, fixedModel #2.2/Ix ASP 152, fixedModel #2.2/Iy THR 22, fixedModel #2.2/J6
THR 2, fixedModel #2.2/JI PRO 11, fixedModel #2.2/JJ MET 1, fixedModel #2.2/JN
ALA 2, fixedModel #2.2/Jw VAL 21, fixedModel #2.2/Jx LYS 11, fixedModel
#2.2/K5 ALA 14, fixedModel #2.2/KI THR 26, fixedModel #2.2/Ke ALA 44,
fixedModel #2.2/Kp PRO 53, fixedModel #2.2/Ks GLU 4, fixedModel #2.2/L3 VAL
52, fixedModel #2.2/LG TRP 20, fixedModel #2.2/LO TYR 37, fixedModel #2.2/LR
SER 78, fixedModel #2.2/LY PRO 182, fixedModel #2.2/M PRO 2, fixedModel
#2.2/Mg ILE 36, fixedModel #2.2/Mq SER 34, fixedModel #2.2/Mr THR 38,
fixedModel #2.2/NF LYS 30, fixedModel #2.2/NM TYR 82, fixedModel #2.2/Np MET
1, fixedModel #2.2/TB MET 18, fixedModel #2.2/Y MET 1, fixedModel #2.2/t0 THR
38, fixedModel #2.2/t1 THR 2, fixedModel #2.2/t2 TYR 37, fixedModel #2.2/t3
PHE 18, fixedModel #2.2/t4 LEU 23, fixedModel #2.2/t5 THR 26, fixedModel
#2.2/t6 MET 1, fixedModel #2.2/t7 MET 1, fixedModel #2.2/t8 VAL 21, fixedModel
#2.2/t9 ASP 152, fixedModel #2.2/ta MET 1, fixedModel #2.2/tb SER 160,
fixedModel #2.2/tc THR 22, fixedModel #2.2/td TYR 26, fixedModel #2.2/te GLU
4, fixedModel #2.2/tf ALA 2, fixedModel #2.2/tg PRO 182, fixedModel #2.2/R MET
1, fixedModel #2.2/A ALA 34, fixedModel #2.2/A0 PRO 204, fixedModel #2.2/AU
LYS 35, fixedModel #2.2/Ab GLU 206, fixedModel #2.2/Aj LYS 208, fixedModel
#2.2/Aq LYS 25, fixedModel #2.2/B ALA 23, fixedModel #2.2/BI ALA 23,
fixedModel #2.2/BK THR 37, fixedModel #2.2/BP GLY 22, fixedModel #2.2/C SER
85, fixedModel #2.2/C0 ILE 33, fixedModel #2.2/C1 ILE 33, fixedModel #2.2/C2
ILE 33, fixedModel #2.2/C3 ILE 33, fixedModel #2.2/C4 SER 34, fixedModel
#2.2/C5 ILE 33, fixedModel #2.2/C6 ILE 33, fixedModel #2.2/C7 ILE 33,
fixedModel #2.2/C8 ILE 33, fixedModel #2.2/C9 ILE 33, fixedModel #2.2/D TYR
18, fixedModel #2.2/D6 VAL 7, fixedModel #2.2/E PHE 33, fixedModel #2.2/E1 LEU
51, fixedModel #2.2/E4 GLN 35, fixedModel #2.2/Ek ASN 26, fixedModel #2.2/Eq
ASN 62, fixedModel #2.2/Es VAL 2, fixedModel #2.2/Ev GLY 3, fixedModel #2.2/F9
HIS 37, fixedModel #2.2/FF HIS 98, fixedModel #2.2/FH VAL 18, fixedModel
#2.2/FL MET 1, fixedModel #2.2/FO PHE 12, fixedModel #2.2/Fy PRO 60,
fixedModel #2.2/Fz VAL 58, fixedModel #2.2/GT ALA 6, fixedModel #2.2/IE LYS
26, fixedModel #2.2/IY SER 2, fixedModel #2.2/JC GLU 22, fixedModel #2.2/a TYR
3  
Chain-initial residues that are not actual N termini: fixedModel #2.2/JI GLU
259, fixedModel #2.2/K5 LYS 143, fixedModel #2.2/K5 ARG 299, fixedModel
#2.2/K5 LYS 338, fixedModel #2.2/K5 ILE 361, fixedModel #2.2/K5 GLU 490,
fixedModel #2.2/K5 MET 567, fixedModel #2.2/L3 TYR 94, fixedModel #2.2/L3 VAL
198, fixedModel #2.2/L3 VAL 312, fixedModel #2.2/NF ARG 189, fixedModel
#2.2/AU GLN 151, fixedModel #2.2/AU GLN 436, fixedModel #2.2/Ab THR 521,
fixedModel #2.2/BK GLN 151, fixedModel #2.2/BK VAL 437, fixedModel #2.2/D ILE
234, fixedModel #2.2/D6 VAL 63, fixedModel #2.2/E GLN 151, fixedModel #2.2/E
GLN 438, fixedModel #2.2/E1 ASP 217, fixedModel #2.2/FF MET 124, fixedModel
#2.2/IE VAL 199  
Chain-final residues that are actual C termini: fixedModel #2.2/R HIS 62,
fixedModel #2.2/A PRO 357, fixedModel #2.2/A0 LYS 685, fixedModel #2.2/AU VAL
574, fixedModel #2.2/Ab ARG 690, fixedModel #2.2/Aj HIS 690, fixedModel
#2.2/Aq GLN 187, fixedModel #2.2/B LYS 160, fixedModel #2.2/BI GLN 187,
fixedModel #2.2/BK VAL 574, fixedModel #2.2/BP GLN 187, fixedModel #2.2/C MET
349, fixedModel #2.2/C0 SER 106, fixedModel #2.2/C1 SER 106, fixedModel
#2.2/C2 SER 106, fixedModel #2.2/C3 SER 106, fixedModel #2.2/C4 SER 106,
fixedModel #2.2/C5 SER 106, fixedModel #2.2/C6 SER 106, fixedModel #2.2/C7 SER
106, fixedModel #2.2/C8 SER 106, fixedModel #2.2/C9 SER 106, fixedModel #2.2/D
VAL 258, fixedModel #2.2/D6 THR 70, fixedModel #2.2/E GLY 575, fixedModel
#2.2/E1 GLY 239, fixedModel #2.2/E4 GLY 203, fixedModel #2.2/Ek SER 103,
fixedModel #2.2/Eq TYR 145, fixedModel #2.2/Es HIS 136, fixedModel #2.2/Ev ALA
386, fixedModel #2.2/F9 GLN 103, fixedModel #2.2/FF PRO 174, fixedModel
#2.2/FH VAL 157, fixedModel #2.2/FL GLY 233, fixedModel #2.2/FO ALA 159,
fixedModel #2.2/Fy ALA 117, fixedModel #2.2/Fz VAL 105, fixedModel #2.2/GT SER
97, fixedModel #2.2/IE GLY 204, fixedModel #2.2/IY ASN 295, fixedModel #2.2/JC
GLU 183, fixedModel #2.2/a GLN 96  
Chain-final residues that are not actual C termini: fixedModel #2.2/AG SER
196, fixedModel #2.2/Ar TRP 118, fixedModel #2.2/I0 LYS 383, fixedModel
#2.2/Il GLU 104, fixedModel #2.2/Ix ILE 279, fixedModel #2.2/Iy GLN 115,
fixedModel #2.2/J6 PHE 199, fixedModel #2.2/JI LYS 491, fixedModel #2.2/JI PHE
252, fixedModel #2.2/JJ ILE 549, fixedModel #2.2/JN VAL 108, fixedModel
#2.2/Jw PHE 144, fixedModel #2.2/Jx ASP 124, fixedModel #2.2/K5 PRO 602,
fixedModel #2.2/K5 ILE 138, fixedModel #2.2/K5 GLU 268, fixedModel #2.2/K5 LEU
311, fixedModel #2.2/K5 VAL 354, fixedModel #2.2/K5 ALA 484, fixedModel
#2.2/K5 ARG 546, fixedModel #2.2/KI GLU 225, fixedModel #2.2/Ke LEU 138,
fixedModel #2.2/Kp GLU 224, fixedModel #2.2/Ks ALA 156, fixedModel #2.2/L3 ARG
325, fixedModel #2.2/L3 LEU 84, fixedModel #2.2/L3 GLY 117, fixedModel #2.2/L3
HIS 283, fixedModel #2.2/LG SER 123, fixedModel #2.2/LO LYS 342, fixedModel
#2.2/LR GLY 148, fixedModel #2.2/LY ALA 345, fixedModel #2.2/M PHE 103,
fixedModel #2.2/Mg ALA 250, fixedModel #2.2/Mq LYS 90, fixedModel #2.2/Mr LEU
147, fixedModel #2.2/NF SER 246, fixedModel #2.2/NF LEU 183, fixedModel
#2.2/NM MET 144, fixedModel #2.2/Np VAL 283, fixedModel #2.2/TB THR 81,
fixedModel #2.2/Y ILE 210, fixedModel #2.2/t0 LEU 147, fixedModel #2.2/t1 PHE
199, fixedModel #2.2/t2 LYS 342, fixedModel #2.2/t3 SER 196, fixedModel
#2.2/t4 TRP 118, fixedModel #2.2/t5 GLU 225, fixedModel #2.2/t6 ILE 549,
fixedModel #2.2/t7 VAL 283, fixedModel #2.2/t8 PHE 144, fixedModel #2.2/t9 ILE
279, fixedModel #2.2/ta ILE 210, fixedModel #2.2/tb LYS 383, fixedModel
#2.2/tc GLN 115, fixedModel #2.2/td GLU 104, fixedModel #2.2/te ALA 156,
fixedModel #2.2/tf VAL 108, fixedModel #2.2/tg ALA 345, fixedModel #2.2/AU LEU
139, fixedModel #2.2/AU ASP 430, fixedModel #2.2/Ab VAL 515, fixedModel
#2.2/BK GLY 138, fixedModel #2.2/BK ASP 430, fixedModel #2.2/D LYS 206,
fixedModel #2.2/D6 LEU 52, fixedModel #2.2/E LEU 139, fixedModel #2.2/E ALA
429, fixedModel #2.2/E1 GLU 123, fixedModel #2.2/FF TYR 118, fixedModel
#2.2/IE VAL 194  
Adding 'H' to fixedModel #2.2/JI GLU 259  
Adding 'H' to fixedModel #2.2/K5 LYS 143  
Adding 'H' to fixedModel #2.2/K5 ARG 299  
Adding 'H' to fixedModel #2.2/K5 LYS 338  
Adding 'H' to fixedModel #2.2/K5 ILE 361  
18 messages similar to the above omitted  
fixedModel #2.2/AG SER 196 is not terminus, removing H atom from 'C'  
fixedModel #2.2/Ar TRP 118 is not terminus, removing H atom from 'C'  
fixedModel #2.2/I0 LYS 383 is not terminus, removing H atom from 'C'  
fixedModel #2.2/Il GLU 104 is not terminus, removing H atom from 'C'  
fixedModel #2.2/Ix ILE 279 is not terminus, removing H atom from 'C'  
43 messages similar to the above omitted  
135029 hydrogens added  
  

Chain HM, residue 1 specifies more than one residue! The simulation can still
run, but this will probably cause problems later if not rectified by
renumbering.  

Deleted the following atoms from residue ALA GT6: O, HC2, CA, HC1, HN3, HN4,
CB, HN2, HC4, HC5, HN5, HC, N, C, HN1, HC3  
Deleted the following atoms from residue PHE GT7: CE2, CE1, CA, O, C, CB, CZ,
CD1, CD2, HA, HE2, HE1, CG, N  

> delete ~#2/GT&#2

> delete ~#2/GT@C,N,CA&#2

Fetching CCD SER_LL_DHG from http://ligand-
expo.rcsb.org/reports/S/SER_LL_DHG/SER_LL_DHG.cif  
Fetching CCD CYS_LL_DHG from http://ligand-
expo.rcsb.org/reports/C/CYS_LL_DHG/CYS_LL_DHG.cif  

> close #1

> close #2

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV1.cif"

Summary of feedback from opening
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV1.cif  
---  
warnings | Unknown polymer entity '1' on line 333  
Unknown polymer entity '2' on line 1763  
Unknown polymer entity '3' on line 2594  
Unknown polymer entity '4' on line 4478  
Unknown polymer entity '5' on line 5142  
61 messages similar to the above omitted  
Atom C13 is not in the residue template for HE9 /HM:1  
Atom OMA is not in the residue template for HEM /HM:1  
Missing or incomplete sequence information. Inferred polymer connectivity.  
  
  
Chain information for superComplexConsolidatedV1.cif #1  
---  
Chain | Description  
A | No description available  
A0 | No description available  
AG t3 | No description available  
AU | No description available  
Ab | No description available  
Aj | No description available  
Aq | No description available  
Ar t4 | No description available  
B | No description available  
BI | No description available  
BK | No description available  
BP | No description available  
C | No description available  
C0 C1 C2 C3 C5 C6 C7 C8 C9 | No description available  
C4 | No description available  
D | No description available  
D6 | No description available  
E | No description available  
E1 | No description available  
E4 | No description available  
Ek | No description available  
Eq | No description available  
Es | No description available  
Ev | No description available  
F9 | No description available  
FF | No description available  
FH | No description available  
FL | No description available  
FO | No description available  
Fy | No description available  
Fz | No description available  
GT | No description available  
I0 tb | No description available  
IE | No description available  
IY | No description available  
Il td | No description available  
Ix t9 | No description available  
Iy tc | No description available  
J6 t1 | No description available  
JC | No description available  
JI | No description available  
JJ t6 | No description available  
JN tf | No description available  
Jw t8 | No description available  
Jx | No description available  
K5 | No description available  
KI t5 | No description available  
Ke | No description available  
Kp | No description available  
Ks te | No description available  
L3 | No description available  
LG | No description available  
LO t2 | No description available  
LR | No description available  
LY tg | No description available  
M | No description available  
Mg | No description available  
Mq | No description available  
Mr t0 | No description available  
NF | No description available  
NM | No description available  
Np t7 | No description available  
R | No description available  
TB | No description available  
Y ta | No description available  
a | No description available  
  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
Chain information for superComplexConsolidatedV1.cif  
---  
Chain | Description  
1.2/A | No description available  
1.2/A0 | No description available  
1.2/AG 1.2/t3 | No description available  
1.2/AU | No description available  
1.2/Ab | No description available  
1.2/Aj | No description available  
1.2/Aq | No description available  
1.2/Ar 1.2/t4 | No description available  
1.2/B | No description available  
1.2/BI | No description available  
1.2/BK | No description available  
1.2/BP | No description available  
1.2/C | No description available  
1.2/C0 1.2/C1 1.2/C2 1.2/C3 1.2/C5 1.2/C6 1.2/C7 1.2/C8 1.2/C9 | No description available  
1.2/C4 | No description available  
1.2/D | No description available  
1.2/D6 | No description available  
1.2/E | No description available  
1.2/E1 | No description available  
1.2/E4 | No description available  
1.2/Ek | No description available  
1.2/Eq | No description available  
1.2/Es | No description available  
1.2/Ev | No description available  
1.2/F9 | No description available  
1.2/FF | No description available  
1.2/FH | No description available  
1.2/FL | No description available  
1.2/FO | No description available  
1.2/Fy | No description available  
1.2/Fz | No description available  
1.2/GT | No description available  
1.2/I0 1.2/tb | No description available  
1.2/IE | No description available  
1.2/IY | No description available  
1.2/Il 1.2/td | No description available  
1.2/Ix 1.2/t9 | No description available  
1.2/Iy 1.2/tc | No description available  
1.2/J6 1.2/t1 | No description available  
1.2/JC | No description available  
1.2/JI | No description available  
1.2/JJ 1.2/t6 | No description available  
1.2/JN 1.2/tf | No description available  
1.2/Jw 1.2/t8 | No description available  
1.2/Jx | No description available  
1.2/K5 | No description available  
1.2/KI 1.2/t5 | No description available  
1.2/Ke | No description available  
1.2/Kp | No description available  
1.2/Ks 1.2/te | No description available  
1.2/L3 | No description available  
1.2/LG | No description available  
1.2/LO 1.2/t2 | No description available  
1.2/LR | No description available  
1.2/LY 1.2/tg | No description available  
1.2/M | No description available  
1.2/Mg | No description available  
1.2/Mq | No description available  
1.2/Mr 1.2/t0 | No description available  
1.2/NF | No description available  
1.2/NM | No description available  
1.2/Np 1.2/t7 | No description available  
1.2/R | No description available  
1.2/TB | No description available  
1.2/Y 1.2/ta | No description available  
1.2/a | No description available  
  

> delete ~#2/GT&#2

> delete ~#1/GT&#1

> select clear

> save "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/GT.pdb"

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/GT.pdb"

Chain information for GT.pdb #2  
---  
Chain | Description  
GT | No description available  
  

> close #2

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/GT2.pdb"

Chain information for GT2.pdb #2  
---  
Chain | Description  
GT | No description available  
  
Computing secondary structure  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
Chain information for GT2.pdb  
---  
Chain | Description  
2.2/GT | No description available  
  

> hide #!1 models

> hide #1.1 models

> hide #!1.2 models

> hide #1.3 models

> addh #2 hbond false

Summary of feedback from adding hydrogens to GT2.pdb #2.2  
---  
warning | Not adding hydrogens to GT2.pdb #2.2/GT ALA 93 CA because it is missing heavy-atom bond partners  
notes | No usable SEQRES records for GT2.pdb (#2.2) chain GT; guessing termini instead  
Chain-initial residues that are actual N termini: GT2.pdb #2.2/GT ALA 6  
Chain-initial residues that are not actual N termini:  
Chain-final residues that are actual C termini:  
Chain-final residues that are not actual C termini: GT2.pdb #2.2/GT ALA 93  
GT2.pdb #2.2/GT ALA 93 is not terminus, removing H atom from 'C'  
703 hydrogens added  
  

> close session

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV1.cif"

Summary of feedback from opening
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV1.cif  
---  
warnings | Unknown polymer entity '1' on line 333  
Unknown polymer entity '2' on line 1763  
Unknown polymer entity '3' on line 2594  
Unknown polymer entity '4' on line 4478  
Unknown polymer entity '5' on line 5142  
61 messages similar to the above omitted  
Atom C13 is not in the residue template for HE9 /HM:1  
Atom OMA is not in the residue template for HEM /HM:1  
Missing or incomplete sequence information. Inferred polymer connectivity.  
  
  
Chain information for superComplexConsolidatedV1.cif #1  
---  
Chain | Description  
A | No description available  
A0 | No description available  
AG t3 | No description available  
AU | No description available  
Ab | No description available  
Aj | No description available  
Aq | No description available  
Ar t4 | No description available  
B | No description available  
BI | No description available  
BK | No description available  
BP | No description available  
C | No description available  
C0 C1 C2 C3 C5 C6 C7 C8 C9 | No description available  
C4 | No description available  
D | No description available  
D6 | No description available  
E | No description available  
E1 | No description available  
E4 | No description available  
Ek | No description available  
Eq | No description available  
Es | No description available  
Ev | No description available  
F9 | No description available  
FF | No description available  
FH | No description available  
FL | No description available  
FO | No description available  
Fy | No description available  
Fz | No description available  
GT | No description available  
I0 tb | No description available  
IE | No description available  
IY | No description available  
Il td | No description available  
Ix t9 | No description available  
Iy tc | No description available  
J6 t1 | No description available  
JC | No description available  
JI | No description available  
JJ t6 | No description available  
JN tf | No description available  
Jw t8 | No description available  
Jx | No description available  
K5 | No description available  
KI t5 | No description available  
Ke | No description available  
Kp | No description available  
Ks te | No description available  
L3 | No description available  
LG | No description available  
LO t2 | No description available  
LR | No description available  
LY tg | No description available  
M | No description available  
Mg | No description available  
Mq | No description available  
Mr t0 | No description available  
NF | No description available  
NM | No description available  
Np t7 | No description available  
R | No description available  
TB | No description available  
Y ta | No description available  
a | No description available  
  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
Chain information for superComplexConsolidatedV1.cif  
---  
Chain | Description  
1.2/A | No description available  
1.2/A0 | No description available  
1.2/AG 1.2/t3 | No description available  
1.2/AU | No description available  
1.2/Ab | No description available  
1.2/Aj | No description available  
1.2/Aq | No description available  
1.2/Ar 1.2/t4 | No description available  
1.2/B | No description available  
1.2/BI | No description available  
1.2/BK | No description available  
1.2/BP | No description available  
1.2/C | No description available  
1.2/C0 1.2/C1 1.2/C2 1.2/C3 1.2/C5 1.2/C6 1.2/C7 1.2/C8 1.2/C9 | No description available  
1.2/C4 | No description available  
1.2/D | No description available  
1.2/D6 | No description available  
1.2/E | No description available  
1.2/E1 | No description available  
1.2/E4 | No description available  
1.2/Ek | No description available  
1.2/Eq | No description available  
1.2/Es | No description available  
1.2/Ev | No description available  
1.2/F9 | No description available  
1.2/FF | No description available  
1.2/FH | No description available  
1.2/FL | No description available  
1.2/FO | No description available  
1.2/Fy | No description available  
1.2/Fz | No description available  
1.2/GT | No description available  
1.2/I0 1.2/tb | No description available  
1.2/IE | No description available  
1.2/IY | No description available  
1.2/Il 1.2/td | No description available  
1.2/Ix 1.2/t9 | No description available  
1.2/Iy 1.2/tc | No description available  
1.2/J6 1.2/t1 | No description available  
1.2/JC | No description available  
1.2/JI | No description available  
1.2/JJ 1.2/t6 | No description available  
1.2/JN 1.2/tf | No description available  
1.2/Jw 1.2/t8 | No description available  
1.2/Jx | No description available  
1.2/K5 | No description available  
1.2/KI 1.2/t5 | No description available  
1.2/Ke | No description available  
1.2/Kp | No description available  
1.2/Ks 1.2/te | No description available  
1.2/L3 | No description available  
1.2/LG | No description available  
1.2/LO 1.2/t2 | No description available  
1.2/LR | No description available  
1.2/LY 1.2/tg | No description available  
1.2/M | No description available  
1.2/Mg | No description available  
1.2/Mq | No description available  
1.2/Mr 1.2/t0 | No description available  
1.2/NF | No description available  
1.2/NM | No description available  
1.2/Np 1.2/t7 | No description available  
1.2/R | No description available  
1.2/TB | No description available  
1.2/Y 1.2/ta | No description available  
1.2/a | No description available  
  

> select clear

> select #1/GT

1489 atoms, 2100 bonds, 92 residues, 1 model selected  

> delete #1/GT

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/GT2.pdb"

Chain information for GT2.pdb #2  
---  
Chain | Description  
GT | No description available  
  
Computing secondary structure  

> combine #1,2

> close #1

> close #2

> rename #3 id #1

> cd "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation"

Current working directory is:
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation  

> runscript /Users/rafaelrocha/Library/CloudStorage/OneDrive-
> Personal/GitHub/KRSPs/modelangeloScripts/correctStructureSequences.py False

> info #1 saveFile chainsInfoTMP.txt

> select #1/AG

1430 atoms, 1462 bonds, 179 residues, 1 model selected  

> save chainsTMP/AG_uu.pdb format pdb models #1/AG selectedOnly true

> open chainsTMP/AG_uu_Mod.pdb

Chain information for AG_uu_Mod.pdb #2  
---  
Chain | Description  
AG | No description available  
  

> select #1/Ar

831 atoms, 860 bonds, 96 residues, 1 model selected  

> save chainsTMP/Ar_ul.pdb format pdb models #1/Ar selectedOnly true

> open chainsTMP/Ar_ul_Mod.pdb

Chain information for Ar_ul_Mod.pdb #3  
---  
Chain | Description  
Ar | No description available  
  

> select #1/I0

1884 atoms, 1936 bonds, 225 residues, 1 model selected  

> save chainsTMP/I0_un.pdb format pdb models #1/I0 selectedOnly true

> open chainsTMP/I0_un_Mod.pdb

Chain information for I0_un_Mod.pdb #4  
---  
Chain | Description  
I0 | No description available  
  

> select #1/Il

664 atoms, 688 bonds, 79 residues, 1 model selected  

> save chainsTMP/Il_ul.pdb format pdb models #1/Il selectedOnly true

> open chainsTMP/Il_ul_Mod.pdb

Chain information for Il_ul_Mod.pdb #5  
---  
Chain | Description  
Il | No description available  
  

> select #1/Ix

1101 atoms, 1145 bonds, 128 residues, 1 model selected  

> save chainsTMP/Ix_ul.pdb format pdb models #1/Ix selectedOnly true

> open chainsTMP/Ix_ul_Mod.pdb

Chain information for Ix_ul_Mod.pdb #6  
---  
Chain | Description  
Ix | No description available  
  

> select #1/Iy

751 atoms, 763 bonds, 94 residues, 1 model selected  

> save chainsTMP/Iy_ul.pdb format pdb models #1/Iy selectedOnly true

> open chainsTMP/Iy_ul_Mod.pdb

Chain information for Iy_ul_Mod.pdb #7  
---  
Chain | Description  
Iy | No description available  
  

> select #1/J6

1621 atoms, 1663 bonds, 198 residues, 1 model selected  

> save chainsTMP/J6_un.pdb format pdb models #1/J6 selectedOnly true

> open chainsTMP/J6_un_Mod.pdb

Chain information for J6_un_Mod.pdb #8  
---  
Chain | Description  
J6 | No description available  
  

> select #1/JI

3646 atoms, 3705 bonds, 1 pseudobond, 475 residues, 2 models selected  

> save chainsTMP/JI_uu.pdb format pdb models #1/JI selectedOnly true

> open chainsTMP/JI_uu_Mod.pdb

Chain information for JI_uu_Mod.pdb #9  
---  
Chain | Description  
JI | No description available  
  

> select #1/JJ

4683 atoms, 4842 bonds, 552 residues, 1 model selected  

> save chainsTMP/JJ_uu.pdb format pdb models #1/JJ selectedOnly true

> open chainsTMP/JJ_uu_Mod.pdb

Chain information for JJ_uu_Mod.pdb #10  
---  
Chain | Description  
JJ | No description available  
  

> select #1/JN

870 atoms, 900 bonds, 107 residues, 1 model selected  

> save chainsTMP/JN_uu.pdb format pdb models #1/JN selectedOnly true

> open chainsTMP/JN_uu_Mod.pdb

Chain information for JN_uu_Mod.pdb #11  
---  
Chain | Description  
JN | No description available  
  

> select #1/Jw

1146 atoms, 1193 bonds, 125 residues, 1 model selected  

> save chainsTMP/Jw_ul.pdb format pdb models #1/Jw selectedOnly true

> open chainsTMP/Jw_ul_Mod.pdb

Chain information for Jw_ul_Mod.pdb #12  
---  
Chain | Description  
Jw | No description available  
  

> select #1/Jx

948 atoms, 976 bonds, 114 residues, 1 model selected  

> save chainsTMP/Jx_ul.pdb format pdb models #1/Jx selectedOnly true

> open chainsTMP/Jx_ul_Mod.pdb

Chain information for Jx_ul_Mod.pdb #13  
---  
Chain | Description  
Jx | No description available  
  

> select #1/K5

3795 atoms, 3864 bonds, 6 pseudobonds, 498 residues, 2 models selected  

> save chainsTMP/K5_un.pdb format pdb models #1/K5 selectedOnly true

> open chainsTMP/K5_un_Mod.pdb

Chain information for K5_un_Mod.pdb #14  
---  
Chain | Description  
K5 | No description available  
  

> select #1/KI

1666 atoms, 1730 bonds, 201 residues, 1 model selected  

> save chainsTMP/KI_uu.pdb format pdb models #1/KI selectedOnly true

> open chainsTMP/KI_uu_Mod.pdb

Chain information for KI_uu_Mod.pdb #15  
---  
Chain | Description  
KI | No description available  
  

> select #1/Ke

741 atoms, 764 bonds, 95 residues, 1 model selected  

> save chainsTMP/Ke_ul.pdb format pdb models #1/Ke selectedOnly true

> open chainsTMP/Ke_ul_Mod.pdb

Chain information for Ke_ul_Mod.pdb #16  
---  
Chain | Description  
Ke | No description available  
  

> select #1/Kp

1379 atoms, 1414 bonds, 172 residues, 1 model selected  

> save chainsTMP/Kp_ul.pdb format pdb models #1/Kp selectedOnly true

> open chainsTMP/Kp_ul_Mod.pdb

Chain information for Kp_ul_Mod.pdb #17  
---  
Chain | Description  
Kp | No description available  
  

> select #1/Ks

1327 atoms, 1375 bonds, 153 residues, 1 model selected  

> save chainsTMP/Ks_ul.pdb format pdb models #1/Ks selectedOnly true

> open chainsTMP/Ks_ul_Mod.pdb

Chain information for Ks_ul_Mod.pdb #18  
---  
Chain | Description  
Ks | No description available  
  

> select #1/L3

1230 atoms, 1253 bonds, 3 pseudobonds, 157 residues, 2 models selected  

> save chainsTMP/L3_un.pdb format pdb models #1/L3 selectedOnly true

> open chainsTMP/L3_un_Mod.pdb

Chain information for L3_un_Mod.pdb #19  
---  
Chain | Description  
L3 | No description available  
  

> select #1/LG

932 atoms, 954 bonds, 105 residues, 1 model selected  

> save chainsTMP/LG_uu.pdb format pdb models #1/LG selectedOnly true

> open chainsTMP/LG_uu_Mod.pdb

Chain information for LG_uu_Mod.pdb #20  
---  
Chain | Description  
LG | No description available  
  

> select #1/LO

2582 atoms, 2626 bonds, 308 residues, 1 model selected  

> save chainsTMP/LO_uu.pdb format pdb models #1/LO selectedOnly true

> open chainsTMP/LO_uu_Mod.pdb

Chain information for LO_uu_Mod.pdb #21  
---  
Chain | Description  
LO | No description available  
  

> select #1/LR

554 atoms, 561 bonds, 71 residues, 1 model selected  

> save chainsTMP/LR_uu.pdb format pdb models #1/LR selectedOnly true

> open chainsTMP/LR_uu_Mod.pdb

Chain information for LR_uu_Mod.pdb #22  
---  
Chain | Description  
LR | No description available  
  

> select #1/LY

1390 atoms, 1441 bonds, 165 residues, 1 model selected  

> save chainsTMP/LY_uu.pdb format pdb models #1/LY selectedOnly true

> open chainsTMP/LY_uu_Mod.pdb

Chain information for LY_uu_Mod.pdb #23  
---  
Chain | Description  
LY | No description available  
  

> select #1/M

819 atoms, 841 bonds, 102 residues, 1 model selected  

> save chainsTMP/M_u.pdb format pdb models #1/M selectedOnly true

> open chainsTMP/M_u_Mod.pdb

Chain information for M_u_Mod.pdb #24  
---  
Chain | Description  
M | No description available  
  

> select #1/Mg

1821 atoms, 1875 bonds, 215 residues, 1 model selected  

> save chainsTMP/Mg_ul.pdb format pdb models #1/Mg selectedOnly true

> open chainsTMP/Mg_ul_Mod.pdb

Chain information for Mg_ul_Mod.pdb #25  
---  
Chain | Description  
Mg | No description available  
  

> select #1/Mq

474 atoms, 492 bonds, 57 residues, 1 model selected  

> save chainsTMP/Mq_ul.pdb format pdb models #1/Mq selectedOnly true

> open chainsTMP/Mq_ul_Mod.pdb

Chain information for Mq_ul_Mod.pdb #26  
---  
Chain | Description  
Mq | No description available  
  

> select #1/Mr

852 atoms, 882 bonds, 110 residues, 1 model selected  

> save chainsTMP/Mr_ul.pdb format pdb models #1/Mr selectedOnly true

> open chainsTMP/Mr_ul_Mod.pdb

Chain information for Mr_ul_Mod.pdb #27  
---  
Chain | Description  
Mr | No description available  
  

> select #1/NF

1651 atoms, 1677 bonds, 1 pseudobond, 212 residues, 2 models selected  

> save chainsTMP/NF_uu.pdb format pdb models #1/NF selectedOnly true

> open chainsTMP/NF_uu_Mod.pdb

Chain information for NF_uu_Mod.pdb #28  
---  
Chain | Description  
NF | No description available  
  

> select #1/NM

504 atoms, 518 bonds, 63 residues, 1 model selected  

> save chainsTMP/NM_uu.pdb format pdb models #1/NM selectedOnly true

> open chainsTMP/NM_uu_Mod.pdb

Chain information for NM_uu_Mod.pdb #29  
---  
Chain | Description  
NM | No description available  
  

> select #1/Np

2489 atoms, 2578 bonds, 285 residues, 1 model selected  

> save chainsTMP/Np_ul.pdb format pdb models #1/Np selectedOnly true

> open chainsTMP/Np_ul_Mod.pdb

Chain information for Np_ul_Mod.pdb #30  
---  
Chain | Description  
Np | No description available  
  

> select #1/TB

479 atoms, 485 bonds, 64 residues, 1 model selected  

> save chainsTMP/TB_uu.pdb format pdb models #1/TB selectedOnly true

> open chainsTMP/TB_uu_Mod.pdb

Chain information for TB_uu_Mod.pdb #31  
---  
Chain | Description  
TB | No description available  
  

> select #1/Y

1742 atoms, 1789 bonds, 211 residues, 1 model selected  

> save chainsTMP/Y_u.pdb format pdb models #1/Y selectedOnly true

> open chainsTMP/Y_u_Mod.pdb

Chain information for Y_u_Mod.pdb #32  
---  
Chain | Description  
Y | No description available  
  

> select #1/t0

853 atoms, 883 bonds, 110 residues, 1 model selected  

> save chainsTMP/t0_ln.pdb format pdb models #1/t0 selectedOnly true

> open chainsTMP/t0_ln_Mod.pdb

Chain information for t0_ln_Mod.pdb #33  
---  
Chain | Description  
t0 | No description available  
  

> select #1/t1

1621 atoms, 1663 bonds, 198 residues, 1 model selected  

> save chainsTMP/t1_ln.pdb format pdb models #1/t1 selectedOnly true

> open chainsTMP/t1_ln_Mod.pdb

Chain information for t1_ln_Mod.pdb #34  
---  
Chain | Description  
t1 | No description available  
  

> select #1/t2

2478 atoms, 2524 bonds, 306 residues, 1 model selected  

> save chainsTMP/t2_ln.pdb format pdb models #1/t2 selectedOnly true

> open chainsTMP/t2_ln_Mod.pdb

Chain information for t2_ln_Mod.pdb #35  
---  
Chain | Description  
t2 | No description available  
  

> select #1/t3

1430 atoms, 1462 bonds, 179 residues, 1 model selected  

> save chainsTMP/t3_ln.pdb format pdb models #1/t3 selectedOnly true

> open chainsTMP/t3_ln_Mod.pdb

Chain information for t3_ln_Mod.pdb #36  
---  
Chain | Description  
t3 | No description available  
  

> select #1/t4

831 atoms, 860 bonds, 96 residues, 1 model selected  

> save chainsTMP/t4_ln.pdb format pdb models #1/t4 selectedOnly true

> open chainsTMP/t4_ln_Mod.pdb

Chain information for t4_ln_Mod.pdb #37  
---  
Chain | Description  
t4 | No description available  
  

> select #1/t5

1666 atoms, 1730 bonds, 201 residues, 1 model selected  

> save chainsTMP/t5_ln.pdb format pdb models #1/t5 selectedOnly true

> open chainsTMP/t5_ln_Mod.pdb

Chain information for t5_ln_Mod.pdb #38  
---  
Chain | Description  
t5 | No description available  
  

> select #1/t6

4626 atoms, 4785 bonds, 552 residues, 1 model selected  

> save chainsTMP/t6_ln.pdb format pdb models #1/t6 selectedOnly true

> open chainsTMP/t6_ln_Mod.pdb

Chain information for t6_ln_Mod.pdb #39  
---  
Chain | Description  
t6 | No description available  
  

> select #1/t7

2489 atoms, 2578 bonds, 285 residues, 1 model selected  

> save chainsTMP/t7_ln.pdb format pdb models #1/t7 selectedOnly true

> open chainsTMP/t7_ln_Mod.pdb

Chain information for t7_ln_Mod.pdb #40  
---  
Chain | Description  
t7 | No description available  
  

> select #1/t8

1146 atoms, 1193 bonds, 125 residues, 1 model selected  

> save chainsTMP/t8_ln.pdb format pdb models #1/t8 selectedOnly true

> open chainsTMP/t8_ln_Mod.pdb

Chain information for t8_ln_Mod.pdb #41  
---  
Chain | Description  
t8 | No description available  
  

> select #1/t9

1102 atoms, 1146 bonds, 128 residues, 1 model selected  

> save chainsTMP/t9_ln.pdb format pdb models #1/t9 selectedOnly true

> open chainsTMP/t9_ln_Mod.pdb

Chain information for t9_ln_Mod.pdb #42  
---  
Chain | Description  
t9 | No description available  
  

> select #1/ta

1688 atoms, 1736 bonds, 210 residues, 1 model selected  

> save chainsTMP/ta_ll.pdb format pdb models #1/ta selectedOnly true

> open chainsTMP/ta_ll_Mod.pdb

Chain information for ta_ll_Mod.pdb #43  
---  
Chain | Description  
ta | No description available  
  

> select #1/tb

2045 atoms, 2095 bonds, 227 residues, 1 model selected  

> save chainsTMP/tb_ll.pdb format pdb models #1/tb selectedOnly true

> open chainsTMP/tb_ll_Mod.pdb

Chain information for tb_ll_Mod.pdb #44  
---  
Chain | Description  
tb | No description available  
  

> select #1/tc

751 atoms, 763 bonds, 94 residues, 1 model selected  

> save chainsTMP/tc_ll.pdb format pdb models #1/tc selectedOnly true

> open chainsTMP/tc_ll_Mod.pdb

Chain information for tc_ll_Mod.pdb #45  
---  
Chain | Description  
tc | No description available  
  

> select #1/td

664 atoms, 688 bonds, 79 residues, 1 model selected  

> save chainsTMP/td_ll.pdb format pdb models #1/td selectedOnly true

> open chainsTMP/td_ll_Mod.pdb

Chain information for td_ll_Mod.pdb #46  
---  
Chain | Description  
td | No description available  
  

> select #1/te

1327 atoms, 1375 bonds, 153 residues, 1 model selected  

> save chainsTMP/te_ll.pdb format pdb models #1/te selectedOnly true

> open chainsTMP/te_ll_Mod.pdb

Chain information for te_ll_Mod.pdb #47  
---  
Chain | Description  
te | No description available  
  

> select #1/tf

870 atoms, 900 bonds, 107 residues, 1 model selected  

> save chainsTMP/tf_ll.pdb format pdb models #1/tf selectedOnly true

> open chainsTMP/tf_ll_Mod.pdb

Chain information for tf_ll_Mod.pdb #48  
---  
Chain | Description  
tf | No description available  
  

> select #1/tg

1347 atoms, 1399 bonds, 164 residues, 1 model selected  

> save chainsTMP/tg_ll.pdb format pdb models #1/tg selectedOnly true

> open chainsTMP/tg_ll_Mod.pdb

Chain information for tg_ll_Mod.pdb #49  
---  
Chain | Description  
tg | No description available  
  

> select #1/R

540 atoms, 564 bonds, 62 residues, 1 model selected  

> save chainsTMP/R_u.pdb format pdb models #1/R selectedOnly true

> open chainsTMP/R_u_Mod.pdb

Chain information for R_u_Mod.pdb #50  
---  
Chain | Description  
R | No description available  
  

> select #1/A

2659 atoms, 2704 bonds, 324 residues, 1 model selected  

> save chainsTMP/A_u.pdb format pdb models #1/A selectedOnly true

> open chainsTMP/A_u_Mod.pdb

Chain information for A_u_Mod.pdb #51  
---  
Chain | Description  
A | No description available  
  

> select #1/A0

3641 atoms, 3696 bonds, 482 residues, 1 model selected  

> save chainsTMP/A0_un.pdb format pdb models #1/A0 selectedOnly true

> open chainsTMP/A0_un_Mod.pdb

Chain information for A0_un_Mod.pdb #52  
---  
Chain | Description  
A0 | No description available  
  

> select #1/AU

4069 atoms, 4141 bonds, 2 pseudobonds, 525 residues, 2 models selected  

> save chainsTMP/AU_uu.pdb format pdb models #1/AU selectedOnly true

> open chainsTMP/AU_uu_Mod.pdb

Chain information for AU_uu_Mod.pdb #53  
---  
Chain | Description  
AU | No description available  
  

> select #1/Ab

3641 atoms, 3693 bonds, 1 pseudobond, 480 residues, 2 models selected  

> save chainsTMP/Ab_ul.pdb format pdb models #1/Ab selectedOnly true

> open chainsTMP/Ab_ul_Mod.pdb

Chain information for Ab_ul_Mod.pdb #54  
---  
Chain | Description  
Ab | No description available  
  

> select #1/Aj

3647 atoms, 3701 bonds, 483 residues, 1 model selected  

> save chainsTMP/Aj_ul.pdb format pdb models #1/Aj selectedOnly true

> open chainsTMP/Aj_ul_Mod.pdb

Chain information for Aj_ul_Mod.pdb #55  
---  
Chain | Description  
Aj | No description available  
  

> select #1/Aq

1320 atoms, 1347 bonds, 163 residues, 1 model selected  

> save chainsTMP/Aq_ul.pdb format pdb models #1/Aq selectedOnly true

> open chainsTMP/Aq_ul_Mod.pdb

Chain information for Aq_ul_Mod.pdb #56  
---  
Chain | Description  
Aq | No description available  
  

> select #1/B

1080 atoms, 1097 bonds, 138 residues, 1 model selected  

> save chainsTMP/B_u.pdb format pdb models #1/B selectedOnly true

> open chainsTMP/B_u_Mod.pdb

Chain information for B_u_Mod.pdb #57  
---  
Chain | Description  
B | No description available  
  

> select #1/BI

1334 atoms, 1361 bonds, 165 residues, 1 model selected  

> save chainsTMP/BI_uu.pdb format pdb models #1/BI selectedOnly true

> open chainsTMP/BI_uu_Mod.pdb

Chain information for BI_uu_Mod.pdb #58  
---  
Chain | Description  
BI | No description available  
  

> select #1/BK

4007 atoms, 4077 bonds, 2 pseudobonds, 520 residues, 2 models selected  

> save chainsTMP/BK_uu.pdb format pdb models #1/BK selectedOnly true

> open chainsTMP/BK_uu_Mod.pdb

Chain information for BK_uu_Mod.pdb #59  
---  
Chain | Description  
BK | No description available  
  

> select #1/BP

1338 atoms, 1365 bonds, 166 residues, 1 model selected  

> save chainsTMP/BP_uu.pdb format pdb models #1/BP selectedOnly true

> open chainsTMP/BP_uu_Mod.pdb

Chain information for BP_uu_Mod.pdb #60  
---  
Chain | Description  
BP | No description available  
  

> select #1/C

1907 atoms, 1933 bonds, 265 residues, 1 model selected  

> save chainsTMP/C_u.pdb format pdb models #1/C selectedOnly true

> open chainsTMP/C_u_Mod.pdb

Chain information for C_u_Mod.pdb #61  
---  
Chain | Description  
C | No description available  
  

> select #1/C0

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C0_un.pdb format pdb models #1/C0 selectedOnly true

> open chainsTMP/C0_un_Mod.pdb

Chain information for C0_un_Mod.pdb #62  
---  
Chain | Description  
C0 | No description available  
  

> select #1/C1

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C1_un.pdb format pdb models #1/C1 selectedOnly true

> open chainsTMP/C1_un_Mod.pdb

Chain information for C1_un_Mod.pdb #63  
---  
Chain | Description  
C1 | No description available  
  

> select #1/C2

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C2_un.pdb format pdb models #1/C2 selectedOnly true

> open chainsTMP/C2_un_Mod.pdb

Chain information for C2_un_Mod.pdb #64  
---  
Chain | Description  
C2 | No description available  
  

> select #1/C3

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C3_un.pdb format pdb models #1/C3 selectedOnly true

> open chainsTMP/C3_un_Mod.pdb

Chain information for C3_un_Mod.pdb #65  
---  
Chain | Description  
C3 | No description available  
  

> select #1/C4

530 atoms, 539 bonds, 73 residues, 1 model selected  

> save chainsTMP/C4_un.pdb format pdb models #1/C4 selectedOnly true

> open chainsTMP/C4_un_Mod.pdb

Chain information for C4_un_Mod.pdb #66  
---  
Chain | Description  
C4 | No description available  
  

> select #1/C5

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C5_un.pdb format pdb models #1/C5 selectedOnly true

> open chainsTMP/C5_un_Mod.pdb

Chain information for C5_un_Mod.pdb #67  
---  
Chain | Description  
C5 | No description available  
  

> select #1/C6

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C6_un.pdb format pdb models #1/C6 selectedOnly true

> open chainsTMP/C6_un_Mod.pdb

Chain information for C6_un_Mod.pdb #68  
---  
Chain | Description  
C6 | No description available  
  

> select #1/C7

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C7_un.pdb format pdb models #1/C7 selectedOnly true

> open chainsTMP/C7_un_Mod.pdb

Chain information for C7_un_Mod.pdb #69  
---  
Chain | Description  
C7 | No description available  
  

> select #1/C8

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C8_un.pdb format pdb models #1/C8 selectedOnly true

> open chainsTMP/C8_un_Mod.pdb

Chain information for C8_un_Mod.pdb #70  
---  
Chain | Description  
C8 | No description available  
  

> select #1/C9

538 atoms, 547 bonds, 74 residues, 1 model selected  

> save chainsTMP/C9_un.pdb format pdb models #1/C9 selectedOnly true

> open chainsTMP/C9_un_Mod.pdb

Chain information for C9_un_Mod.pdb #71  
---  
Chain | Description  
C9 | No description available  
  

> select #1/D

1695 atoms, 1727 bonds, 1 pseudobond, 214 residues, 2 models selected  

> save chainsTMP/D_u.pdb format pdb models #1/D selectedOnly true

> open chainsTMP/D_u_Mod.pdb

Chain information for D_u_Mod.pdb #72  
---  
Chain | Description  
D | No description available  
  

> select #1/D6

437 atoms, 447 bonds, 1 pseudobond, 54 residues, 2 models selected  

> save chainsTMP/D6_un.pdb format pdb models #1/D6 selectedOnly true

> open chainsTMP/D6_un_Mod.pdb

Chain information for D6_un_Mod.pdb #73  
---  
Chain | Description  
D6 | No description available  
  

> select #1/E

4072 atoms, 4145 bonds, 2 pseudobonds, 526 residues, 2 models selected  

> save chainsTMP/E_u.pdb format pdb models #1/E selectedOnly true

> open chainsTMP/E_u_Mod.pdb

Chain information for E_u_Mod.pdb #74  
---  
Chain | Description  
E | No description available  
  

> select #1/E1

608 atoms, 625 bonds, 1 pseudobond, 80 residues, 2 models selected  

> save chainsTMP/E1_un.pdb format pdb models #1/E1 selectedOnly true

> open chainsTMP/E1_un_Mod.pdb

Chain information for E1_un_Mod.pdb #75  
---  
Chain | Description  
E1 | No description available  
  

> select #1/E4

1397 atoms, 1429 bonds, 169 residues, 1 model selected  

> save chainsTMP/E4_un.pdb format pdb models #1/E4 selectedOnly true

> open chainsTMP/E4_un_Mod.pdb

Chain information for E4_un_Mod.pdb #76  
---  
Chain | Description  
E4 | No description available  
  

> select #1/Ek

670 atoms, 695 bonds, 78 residues, 1 model selected  

> save chainsTMP/Ek_ul.pdb format pdb models #1/Ek selectedOnly true

> open chainsTMP/Ek_ul_Mod.pdb

Chain information for Ek_ul_Mod.pdb #77  
---  
Chain | Description  
Ek | No description available  
  

> select #1/Eq

772 atoms, 805 bonds, 84 residues, 1 model selected  

> save chainsTMP/Eq_ul.pdb format pdb models #1/Eq selectedOnly true

> open chainsTMP/Eq_ul_Mod.pdb

Chain information for Eq_ul_Mod.pdb #78  
---  
Chain | Description  
Eq | No description available  
  

> select #1/Es

1117 atoms, 1156 bonds, 135 residues, 1 model selected  

> save chainsTMP/Es_ul.pdb format pdb models #1/Es selectedOnly true

> open chainsTMP/Es_ul_Mod.pdb

Chain information for Es_ul_Mod.pdb #79  
---  
Chain | Description  
Es | No description available  
  

> select #1/Ev

3194 atoms, 3290 bonds, 384 residues, 1 model selected  

> save chainsTMP/Ev_ul.pdb format pdb models #1/Ev selectedOnly true

> open chainsTMP/Ev_ul_Mod.pdb

Chain information for Ev_ul_Mod.pdb #80  
---  
Chain | Description  
Ev | No description available  
  

> select #1/F9

595 atoms, 621 bonds, 67 residues, 1 model selected  

> save chainsTMP/F9_un.pdb format pdb models #1/F9 selectedOnly true

> open chainsTMP/F9_un_Mod.pdb

Chain information for F9_un_Mod.pdb #81  
---  
Chain | Description  
F9 | No description available  
  

> select #1/FF

596 atoms, 618 bonds, 1 pseudobond, 72 residues, 2 models selected  

> save chainsTMP/FF_uu.pdb format pdb models #1/FF selectedOnly true

> open chainsTMP/FF_uu_Mod.pdb

Chain information for FF_uu_Mod.pdb #82  
---  
Chain | Description  
FF | No description available  
  

> select #1/FH

1138 atoms, 1176 bonds, 140 residues, 1 model selected  

> save chainsTMP/FH_uu.pdb format pdb models #1/FH selectedOnly true

> open chainsTMP/FH_uu_Mod.pdb

Chain information for FH_uu_Mod.pdb #83  
---  
Chain | Description  
FH | No description available  
  

> select #1/FL

1998 atoms, 2068 bonds, 233 residues, 1 model selected  

> save chainsTMP/FL_uu.pdb format pdb models #1/FL selectedOnly true

> open chainsTMP/FL_uu_Mod.pdb

Chain information for FL_uu_Mod.pdb #84  
---  
Chain | Description  
FL | No description available  
  

> select #1/FO

1174 atoms, 1201 bonds, 148 residues, 1 model selected  

> save chainsTMP/FO_uu.pdb format pdb models #1/FO selectedOnly true

> open chainsTMP/FO_uu_Mod.pdb

Chain information for FO_uu_Mod.pdb #85  
---  
Chain | Description  
FO | No description available  
  

> select #1/Fy

480 atoms, 491 bonds, 58 residues, 1 model selected  

> save chainsTMP/Fy_ul.pdb format pdb models #1/Fy selectedOnly true

> open chainsTMP/Fy_ul_Mod.pdb

Chain information for Fy_ul_Mod.pdb #86  
---  
Chain | Description  
Fy | No description available  
  

> select #1/Fz

402 atoms, 412 bonds, 48 residues, 1 model selected  

> save chainsTMP/Fz_ul.pdb format pdb models #1/Fz selectedOnly true

> open chainsTMP/Fz_ul_Mod.pdb

Chain information for Fz_ul_Mod.pdb #87  
---  
Chain | Description  
Fz | No description available  
  

> select #1/IE

1375 atoms, 1402 bonds, 1 pseudobond, 175 residues, 2 models selected  

> save chainsTMP/IE_uu.pdb format pdb models #1/IE selectedOnly true

> open chainsTMP/IE_uu_Mod.pdb

Chain information for IE_uu_Mod.pdb #88  
---  
Chain | Description  
IE | No description available  
  

> select #1/IY

2336 atoms, 2377 bonds, 294 residues, 1 model selected  

> save chainsTMP/IY_uu.pdb format pdb models #1/IY selectedOnly true

> open chainsTMP/IY_uu_Mod.pdb

Chain information for IY_uu_Mod.pdb #89  
---  
Chain | Description  
IY | No description available  
  

> select #1/JC

1254 atoms, 1276 bonds, 162 residues, 1 model selected  

> save chainsTMP/JC_uu.pdb format pdb models #1/JC selectedOnly true

> open chainsTMP/JC_uu_Mod.pdb

Chain information for JC_uu_Mod.pdb #90  
---  
Chain | Description  
JC | No description available  
  

> select #1/a

799 atoms, 822 bonds, 94 residues, 1 model selected  

> save chainsTMP/a_l.pdb format pdb models #1/a selectedOnly true

> open chainsTMP/a_l_Mod.pdb

Chain information for a_l_Mod.pdb #91  
---  
Chain | Description  
a | No description available  
  

> select #1/HM

120 atoms, 126 bonds, 8 pseudobonds, 3 residues, 2 models selected  

> save chainsTMP/HM_uu.pdb format pdb models #1/HM selectedOnly true

> open chainsTMP/HM_uu_Mod.pdb

> select #1/FS

19 atoms, 25 bonds, 3 residues, 1 model selected  

> save chainsTMP/FS_uu.pdb format pdb models #1/FS selectedOnly true

> open chainsTMP/FS_uu_Mod.pdb

> select #1/FD

53 atoms, 58 bonds, 1 residue, 1 model selected  

> save chainsTMP/FD_uu.pdb format pdb models #1/FD selectedOnly true

> open chainsTMP/FD_uu_Mod.pdb

> select #1/HN

120 atoms, 126 bonds, 8 pseudobonds, 2 residues, 2 models selected  

> save chainsTMP/HN_uu.pdb format pdb models #1/HN selectedOnly true

> open chainsTMP/HN_uu_Mod.pdb

> select #1/HO

43 atoms, 46 bonds, 4 pseudobonds, 1 residue, 2 models selected  

> save chainsTMP/HO_uu.pdb format pdb models #1/HO selectedOnly true

> open chainsTMP/HO_uu_Mod.pdb

> select #1/GT

721 atoms, 739 bonds, 88 residues, 1 model selected  

> save chainsTMP/GT_uu.pdb format pdb models #1/GT selectedOnly true

> open chainsTMP/GT_uu_Mod.pdb

Chain information for GT_uu_Mod.pdb #97  
---  
Chain | Description  
GT | No description available  
  

> combine #2-97 close true modelId #2 name fixedModel

Computing secondary structure  
[Repeated 95 time(s)]

> save "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV1.cif"
> models #2

Not saving entity_poly_seq for non-authoritative sequences  

> close session

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV1.cif"

Summary of feedback from opening
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV1.cif  
---  
warnings | Unknown polymer entity '1' on line 333  
Unknown polymer entity '2' on line 1763  
Unknown polymer entity '3' on line 2594  
Unknown polymer entity '4' on line 4478  
Unknown polymer entity '5' on line 5142  
61 messages similar to the above omitted  
Atom OMA is not in the residue template for HEM /HM:1  
Atom C13 is not in the residue template for HE9 /HM:1  
Missing or incomplete sequence information. Inferred polymer connectivity.  
  
  
Chain information for superComplexConsolidatedV1.cif #1  
---  
Chain | Description  
A | No description available  
A0 | No description available  
AG t3 | No description available  
AU | No description available  
Ab | No description available  
Aj | No description available  
Aq | No description available  
Ar t4 | No description available  
B | No description available  
BI | No description available  
BK | No description available  
BP | No description available  
C | No description available  
C0 C1 C2 C3 C5 C6 C7 C8 C9 | No description available  
C4 | No description available  
D | No description available  
D6 | No description available  
E | No description available  
E1 | No description available  
E4 | No description available  
Ek | No description available  
Eq | No description available  
Es | No description available  
Ev | No description available  
F9 | No description available  
FF | No description available  
FH | No description available  
FL | No description available  
FO | No description available  
Fy | No description available  
Fz | No description available  
GT | No description available  
I0 tb | No description available  
IE | No description available  
IY | No description available  
Il td | No description available  
Ix t9 | No description available  
Iy tc | No description available  
J6 t1 | No description available  
JC | No description available  
JI | No description available  
JJ t6 | No description available  
JN tf | No description available  
Jw t8 | No description available  
Jx | No description available  
K5 | No description available  
KI t5 | No description available  
Ke | No description available  
Kp | No description available  
Ks te | No description available  
L3 | No description available  
LG | No description available  
LO t2 | No description available  
LR | No description available  
LY tg | No description available  
M | No description available  
Mg | No description available  
Mq | No description available  
Mr t0 | No description available  
NF | No description available  
NM | No description available  
Np t7 | No description available  
R | No description available  
TB | No description available  
Y ta | No description available  
a | No description available  
  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp.mrc"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #2, grid size
500,500,500, pixel 1.21, shown at level 0.118, step 2, values float32  

> clipper associate #2 toModel #1

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #1.1.1.1, grid size
500,500,500, pixel 1.21, shown at level 0.201, step 1, values float32  
Chain information for superComplexConsolidatedV1.cif  
---  
Chain | Description  
1.2/A | No description available  
1.2/A0 | No description available  
1.2/AG 1.2/t3 | No description available  
1.2/AU | No description available  
1.2/Ab | No description available  
1.2/Aj | No description available  
1.2/Aq | No description available  
1.2/Ar 1.2/t4 | No description available  
1.2/B | No description available  
1.2/BI | No description available  
1.2/BK | No description available  
1.2/BP | No description available  
1.2/C | No description available  
1.2/C0 1.2/C1 1.2/C2 1.2/C3 1.2/C5 1.2/C6 1.2/C7 1.2/C8 1.2/C9 | No description available  
1.2/C4 | No description available  
1.2/D | No description available  
1.2/D6 | No description available  
1.2/E | No description available  
1.2/E1 | No description available  
1.2/E4 | No description available  
1.2/Ek | No description available  
1.2/Eq | No description available  
1.2/Es | No description available  
1.2/Ev | No description available  
1.2/F9 | No description available  
1.2/FF | No description available  
1.2/FH | No description available  
1.2/FL | No description available  
1.2/FO | No description available  
1.2/Fy | No description available  
1.2/Fz | No description available  
1.2/GT | No description available  
1.2/I0 1.2/tb | No description available  
1.2/IE | No description available  
1.2/IY | No description available  
1.2/Il 1.2/td | No description available  
1.2/Ix 1.2/t9 | No description available  
1.2/Iy 1.2/tc | No description available  
1.2/J6 1.2/t1 | No description available  
1.2/JC | No description available  
1.2/JI | No description available  
1.2/JJ 1.2/t6 | No description available  
1.2/JN 1.2/tf | No description available  
1.2/Jw 1.2/t8 | No description available  
1.2/Jx | No description available  
1.2/K5 | No description available  
1.2/KI 1.2/t5 | No description available  
1.2/Ke | No description available  
1.2/Kp | No description available  
1.2/Ks 1.2/te | No description available  
1.2/L3 | No description available  
1.2/LG | No description available  
1.2/LO 1.2/t2 | No description available  
1.2/LR | No description available  
1.2/LY 1.2/tg | No description available  
1.2/M | No description available  
1.2/Mg | No description available  
1.2/Mq | No description available  
1.2/Mr 1.2/t0 | No description available  
1.2/NF | No description available  
1.2/NM | No description available  
1.2/Np 1.2/t7 | No description available  
1.2/R | No description available  
1.2/TB | No description available  
1.2/Y 1.2/ta | No description available  
1.2/a | No description available  
  

> volume #1.1.1.1 style surface

> transparency 50

> addh #1 hbond false

Summary of feedback from adding hydrogens to superComplexConsolidatedV1.cif
#1.2  
---  
warning | Not adding hydrogens to /GT ALA 93 CA because it is missing heavy-atom bond partners  
notes | No usable SEQRES records for superComplexConsolidatedV1.cif (#1.2) chain A; guessing termini instead  
No usable SEQRES records for superComplexConsolidatedV1.cif (#1.2) chain A0;
guessing termini instead  
No usable SEQRES records for superComplexConsolidatedV1.cif (#1.2) chain AG;
guessing termini instead  
No usable SEQRES records for superComplexConsolidatedV1.cif (#1.2) chain AU;
guessing termini instead  
No usable SEQRES records for superComplexConsolidatedV1.cif (#1.2) chain Ab;
guessing termini instead  
86 messages similar to the above omitted  
Chain-initial residues that are actual N termini: /A ALA 34, /A0 PRO 204, /AG
PHE 18, /AU LYS 35, /Ab GLU 206, /Aj LYS 208, /Aq LYS 25, /Ar LEU 23, /B ALA
23, /BI ALA 23, /BK THR 37, /BP GLY 22, /C SER 85, /C0 ILE 33, /C1 ILE 33, /C2
ILE 33, /C3 ILE 33, /C4 SER 34, /C5 ILE 33, /C6 ILE 33, /C7 ILE 33, /C8 ILE
33, /C9 ILE 33, /D TYR 18, /D6 VAL 7, /E PHE 33, /E1 LEU 51, /E4 GLN 35, /Ek
ASN 26, /Eq ASN 62, /Es VAL 2, /Ev GLY 3, /F9 HIS 37, /FF HIS 98, /FH VAL 18,
/FL MET 1, /FO PHE 12, /Fy PRO 60, /Fz VAL 58, /GT ALA 6, /I0 SER 160, /IE LYS
26, /IY SER 2, /Il TYR 26, /Ix ASP 152, /Iy THR 22, /J6 THR 2, /JC GLU 22, /JI
PRO 11, /JJ MET 1, /JN ALA 2, /Jw VAL 21, /Jx LYS 11, /K5 ALA 14, /KI THR 26,
/Ke ALA 44, /Kp PRO 53, /Ks GLU 4, /L3 VAL 52, /LG TRP 20, /LO TYR 37, /LR SER
78, /LY PRO 182, /M PRO 2, /Mg ILE 36, /Mq SER 34, /Mr THR 38, /NF LYS 30, /NM
TYR 82, /Np MET 1, /R MET 1, /TB MET 18, /Y MET 1, /a TYR 3, /t0 THR 38, /t1
THR 2, /t2 TYR 37, /t3 PHE 18, /t4 LEU 23, /t5 THR 26, /t6 MET 1, /t7 MET 1,
/t8 VAL 21, /t9 ASP 152, /ta MET 1, /tb SER 160, /tc THR 22, /td TYR 26, /te
GLU 4, /tf ALA 2, /tg PRO 182  
Chain-initial residues that are not actual N termini: /AU GLN 151, /AU GLN
436, /Ab THR 521, /BK GLN 151, /BK VAL 437, /D ILE 234, /D6 VAL 63, /E GLN
151, /E GLN 438, /E1 ASP 217, /FF MET 124, /IE VAL 199, /JI GLU 259, /K5 LYS
143, /K5 ARG 299, /K5 LYS 338, /K5 ILE 361, /K5 GLU 490, /K5 MET 567, /L3 TYR
94, /L3 VAL 198, /L3 VAL 312, /NF ARG 189  
Chain-final residues that are actual C termini: /A PRO 357, /A0 LYS 685, /AU
VAL 574, /Ab ARG 690, /Aj HIS 690, /Aq GLN 187, /B LYS 160, /BI GLN 187, /BK
VAL 574, /BP GLN 187, /C MET 349, /C0 SER 106, /C1 SER 106, /C2 SER 106, /C3
SER 106, /C4 SER 106, /C5 SER 106, /C6 SER 106, /C7 SER 106, /C8 SER 106, /C9
SER 106, /D VAL 258, /D6 THR 70, /E GLY 575, /E1 GLY 239, /E4 GLY 203, /Ek SER
103, /Eq TYR 145, /Es HIS 136, /Ev ALA 386, /F9 GLN 103, /FF PRO 174, /FH VAL
157, /FL GLY 233, /FO ALA 159, /Fy ALA 117, /Fz VAL 105, /IE GLY 204, /IY ASN
295, /JC GLU 183, /R HIS 62, /a GLN 96  
Chain-final residues that are not actual C termini: /AG SER 196, /AU LEU 139,
/AU ASP 430, /Ab VAL 515, /Ar TRP 118, /BK GLY 138, /BK ASP 430, /D LYS 206,
/D6 LEU 52, /E LEU 139, /E ALA 429, /E1 GLU 123, /FF TYR 118, /GT ALA 93, /I0
LYS 383, /IE VAL 194, /Il GLU 104, /Ix ILE 279, /Iy GLN 115, /J6 PHE 199, /JI
LYS 491, /JI PHE 252, /JJ ILE 549, /JN VAL 108, /Jw PHE 144, /Jx ASP 124, /K5
PRO 602, /K5 ILE 138, /K5 GLU 268, /K5 LEU 311, /K5 VAL 354, /K5 ALA 484, /K5
ARG 546, /KI GLU 225, /Ke LEU 138, /Kp GLU 224, /Ks ALA 156, /L3 ARG 325, /L3
LEU 84, /L3 GLY 117, /L3 HIS 283, /LG SER 123, /LO LYS 342, /LR GLY 148, /LY
ALA 345, /M PHE 103, /Mg ALA 250, /Mq LYS 90, /Mr LEU 147, /NF SER 246, /NF
LEU 183, /NM MET 144, /Np VAL 283, /TB THR 81, /Y ILE 210, /t0 LEU 147, /t1
PHE 199, /t2 LYS 342, /t3 SER 196, /t4 TRP 118, /t5 GLU 225, /t6 ILE 549, /t7
VAL 283, /t8 PHE 144, /t9 ILE 279, /ta ILE 210, /tb LYS 383, /tc GLN 115, /td
GLU 104, /te ALA 156, /tf VAL 108, /tg ALA 345  
Adding 'H' to /AU GLN 151  
Adding 'H' to /AU GLN 436  
Adding 'H' to /Ab THR 521  
Adding 'H' to /BK GLN 151  
Adding 'H' to /BK VAL 437  
18 messages similar to the above omitted  
/AG SER 196 is not terminus, removing H atom from 'C'  
/Ar TRP 118 is not terminus, removing H atom from 'C'  
/GT ALA 93 is not terminus, removing H atom from 'C'  
/I0 LYS 383 is not terminus, removing H atom from 'C'  
/Il GLU 104 is not terminus, removing H atom from 'C'  
44 messages similar to the above omitted  
134990 hydrogens added  
  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  

> select clear

Chain HM, residue 1 specifies more than one residue! The simulation can still
run, but this will probably cause problems later if not rectified by
renumbering.  

Deleted the following atoms from residue FAD FD1: H7M3, H6A2, H6A1, H1', H5',
H7M1, H1'', H8M1, H8M3, H3, HO2B, H5'', H1, H5B2, HO3B, H7M2, H5B1, H8M2  
Deleted the following atoms from residue F3S FS3: S1, S4, FE3  

> close session

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV1.cif"

Summary of feedback from opening
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV1.cif  
---  
warnings | Unknown polymer entity '1' on line 333  
Unknown polymer entity '2' on line 1763  
Unknown polymer entity '3' on line 2594  
Unknown polymer entity '4' on line 4478  
Unknown polymer entity '5' on line 5142  
61 messages similar to the above omitted  
Atom OMA is not in the residue template for HEM /HM:1  
Atom C13 is not in the residue template for HE9 /HM:1  
Missing or incomplete sequence information. Inferred polymer connectivity.  
  
  
Chain information for superComplexConsolidatedV1.cif #1  
---  
Chain | Description  
A | No description available  
A0 | No description available  
AG t3 | No description available  
AU | No description available  
Ab | No description available  
Aj | No description available  
Aq | No description available  
Ar t4 | No description available  
B | No description available  
BI | No description available  
BK | No description available  
BP | No description available  
C | No description available  
C0 C1 C2 C3 C5 C6 C7 C8 C9 | No description available  
C4 | No description available  
D | No description available  
D6 | No description available  
E | No description available  
E1 | No description available  
E4 | No description available  
Ek | No description available  
Eq | No description available  
Es | No description available  
Ev | No description available  
F9 | No description available  
FF | No description available  
FH | No description available  
FL | No description available  
FO | No description available  
Fy | No description available  
Fz | No description available  
GT | No description available  
I0 tb | No description available  
IE | No description available  
IY | No description available  
Il td | No description available  
Ix t9 | No description available  
Iy tc | No description available  
J6 t1 | No description available  
JC | No description available  
JI | No description available  
JJ t6 | No description available  
JN tf | No description available  
Jw t8 | No description available  
Jx | No description available  
K5 | No description available  
KI t5 | No description available  
Ke | No description available  
Kp | No description available  
Ks te | No description available  
L3 | No description available  
LG | No description available  
LO t2 | No description available  
LR | No description available  
LY tg | No description available  
M | No description available  
Mg | No description available  
Mq | No description available  
Mr t0 | No description available  
NF | No description available  
NM | No description available  
Np t7 | No description available  
R | No description available  
TB | No description available  
Y ta | No description available  
a | No description available  
  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp.mrc"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #2, grid size
500,500,500, pixel 1.21, shown at level 0.118, step 2, values float32  

> addh #1 hbond false

Summary of feedback from adding hydrogens to superComplexConsolidatedV1.cif #1  
---  
warning | Not adding hydrogens to /GT ALA 93 CA because it is missing heavy-atom bond partners  
notes | No usable SEQRES records for superComplexConsolidatedV1.cif (#1) chain A; guessing termini instead  
No usable SEQRES records for superComplexConsolidatedV1.cif (#1) chain A0;
guessing termini instead  
No usable SEQRES records for superComplexConsolidatedV1.cif (#1) chain AG;
guessing termini instead  
No usable SEQRES records for superComplexConsolidatedV1.cif (#1) chain AU;
guessing termini instead  
No usable SEQRES records for superComplexConsolidatedV1.cif (#1) chain Ab;
guessing termini instead  
86 messages similar to the above omitted  
Chain-initial residues that are actual N termini: /A ALA 34, /A0 PRO 204, /AG
PHE 18, /AU LYS 35, /Ab GLU 206, /Aj LYS 208, /Aq LYS 25, /Ar LEU 23, /B ALA
23, /BI ALA 23, /BK THR 37, /BP GLY 22, /C SER 85, /C0 ILE 33, /C1 ILE 33, /C2
ILE 33, /C3 ILE 33, /C4 SER 34, /C5 ILE 33, /C6 ILE 33, /C7 ILE 33, /C8 ILE
33, /C9 ILE 33, /D TYR 18, /D6 VAL 7, /E PHE 33, /E1 LEU 51, /E4 GLN 35, /Ek
ASN 26, /Eq ASN 62, /Es VAL 2, /Ev GLY 3, /F9 HIS 37, /FF HIS 98, /FH VAL 18,
/FL MET 1, /FO PHE 12, /Fy PRO 60, /Fz VAL 58, /GT ALA 6, /I0 SER 160, /IE LYS
26, /IY SER 2, /Il TYR 26, /Ix ASP 152, /Iy THR 22, /J6 THR 2, /JC GLU 22, /JI
PRO 11, /JJ MET 1, /JN ALA 2, /Jw VAL 21, /Jx LYS 11, /K5 ALA 14, /KI THR 26,
/Ke ALA 44, /Kp PRO 53, /Ks GLU 4, /L3 VAL 52, /LG TRP 20, /LO TYR 37, /LR SER
78, /LY PRO 182, /M PRO 2, /Mg ILE 36, /Mq SER 34, /Mr THR 38, /NF LYS 30, /NM
TYR 82, /Np MET 1, /R MET 1, /TB MET 18, /Y MET 1, /a TYR 3, /t0 THR 38, /t1
THR 2, /t2 TYR 37, /t3 PHE 18, /t4 LEU 23, /t5 THR 26, /t6 MET 1, /t7 MET 1,
/t8 VAL 21, /t9 ASP 152, /ta MET 1, /tb SER 160, /tc THR 22, /td TYR 26, /te
GLU 4, /tf ALA 2, /tg PRO 182  
Chain-initial residues that are not actual N termini: /AU GLN 151, /AU GLN
436, /Ab THR 521, /BK GLN 151, /BK VAL 437, /D ILE 234, /D6 VAL 63, /E GLN
151, /E GLN 438, /E1 ASP 217, /FF MET 124, /IE VAL 199, /JI GLU 259, /K5 LYS
143, /K5 ARG 299, /K5 LYS 338, /K5 ILE 361, /K5 GLU 490, /K5 MET 567, /L3 TYR
94, /L3 VAL 198, /L3 VAL 312, /NF ARG 189  
Chain-final residues that are actual C termini: /A PRO 357, /A0 LYS 685, /AU
VAL 574, /Ab ARG 690, /Aj HIS 690, /Aq GLN 187, /B LYS 160, /BI GLN 187, /BK
VAL 574, /BP GLN 187, /C MET 349, /C0 SER 106, /C1 SER 106, /C2 SER 106, /C3
SER 106, /C4 SER 106, /C5 SER 106, /C6 SER 106, /C7 SER 106, /C8 SER 106, /C9
SER 106, /D VAL 258, /D6 THR 70, /E GLY 575, /E1 GLY 239, /E4 GLY 203, /Ek SER
103, /Eq TYR 145, /Es HIS 136, /Ev ALA 386, /F9 GLN 103, /FF PRO 174, /FH VAL
157, /FL GLY 233, /FO ALA 159, /Fy ALA 117, /Fz VAL 105, /IE GLY 204, /IY ASN
295, /JC GLU 183, /R HIS 62, /a GLN 96  
Chain-final residues that are not actual C termini: /AG SER 196, /AU LEU 139,
/AU ASP 430, /Ab VAL 515, /Ar TRP 118, /BK GLY 138, /BK ASP 430, /D LYS 206,
/D6 LEU 52, /E LEU 139, /E ALA 429, /E1 GLU 123, /FF TYR 118, /GT ALA 93, /I0
LYS 383, /IE VAL 194, /Il GLU 104, /Ix ILE 279, /Iy GLN 115, /J6 PHE 199, /JI
LYS 491, /JI PHE 252, /JJ ILE 549, /JN VAL 108, /Jw PHE 144, /Jx ASP 124, /K5
PRO 602, /K5 ILE 138, /K5 GLU 268, /K5 LEU 311, /K5 VAL 354, /K5 ALA 484, /K5
ARG 546, /KI GLU 225, /Ke LEU 138, /Kp GLU 224, /Ks ALA 156, /L3 ARG 325, /L3
LEU 84, /L3 GLY 117, /L3 HIS 283, /LG SER 123, /LO LYS 342, /LR GLY 148, /LY
ALA 345, /M PHE 103, /Mg ALA 250, /Mq LYS 90, /Mr LEU 147, /NF SER 246, /NF
LEU 183, /NM MET 144, /Np VAL 283, /TB THR 81, /Y ILE 210, /t0 LEU 147, /t1
PHE 199, /t2 LYS 342, /t3 SER 196, /t4 TRP 118, /t5 GLU 225, /t6 ILE 549, /t7
VAL 283, /t8 PHE 144, /t9 ILE 279, /ta ILE 210, /tb LYS 383, /tc GLN 115, /td
GLU 104, /te ALA 156, /tf VAL 108, /tg ALA 345  
Adding 'H' to /AU GLN 151  
Adding 'H' to /AU GLN 436  
Adding 'H' to /Ab THR 521  
Adding 'H' to /BK GLN 151  
Adding 'H' to /BK VAL 437  
18 messages similar to the above omitted  
/AG SER 196 is not terminus, removing H atom from 'C'  
/Ar TRP 118 is not terminus, removing H atom from 'C'  
/GT ALA 93 is not terminus, removing H atom from 'C'  
/I0 LYS 383 is not terminus, removing H atom from 'C'  
/Il GLU 104 is not terminus, removing H atom from 'C'  
44 messages similar to the above omitted  
134990 hydrogens added  
  

> clipper associate #2 toModel #1

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #1.1.1.1, grid size
500,500,500, pixel 1.21, shown at level 0.201, step 1, values float32  
Chain information for superComplexConsolidatedV1.cif  
---  
Chain | Description  
1.2/A | No description available  
1.2/A0 | No description available  
1.2/AG 1.2/t3 | No description available  
1.2/AU | No description available  
1.2/Ab | No description available  
1.2/Aj | No description available  
1.2/Aq | No description available  
1.2/Ar 1.2/t4 | No description available  
1.2/B | No description available  
1.2/BI | No description available  
1.2/BK | No description available  
1.2/BP | No description available  
1.2/C | No description available  
1.2/C0 1.2/C1 1.2/C2 1.2/C3 1.2/C5 1.2/C6 1.2/C7 1.2/C8 1.2/C9 | No description available  
1.2/C4 | No description available  
1.2/D | No description available  
1.2/D6 | No description available  
1.2/E | No description available  
1.2/E1 | No description available  
1.2/E4 | No description available  
1.2/Ek | No description available  
1.2/Eq | No description available  
1.2/Es | No description available  
1.2/Ev | No description available  
1.2/F9 | No description available  
1.2/FF | No description available  
1.2/FH | No description available  
1.2/FL | No description available  
1.2/FO | No description available  
1.2/Fy | No description available  
1.2/Fz | No description available  
1.2/GT | No description available  
1.2/I0 1.2/tb | No description available  
1.2/IE | No description available  
1.2/IY | No description available  
1.2/Il 1.2/td | No description available  
1.2/Ix 1.2/t9 | No description available  
1.2/Iy 1.2/tc | No description available  
1.2/J6 1.2/t1 | No description available  
1.2/JC | No description available  
1.2/JI | No description available  
1.2/JJ 1.2/t6 | No description available  
1.2/JN 1.2/tf | No description available  
1.2/Jw 1.2/t8 | No description available  
1.2/Jx | No description available  
1.2/K5 | No description available  
1.2/KI 1.2/t5 | No description available  
1.2/Ke | No description available  
1.2/Kp | No description available  
1.2/Ks 1.2/te | No description available  
1.2/L3 | No description available  
1.2/LG | No description available  
1.2/LO 1.2/t2 | No description available  
1.2/LR | No description available  
1.2/LY 1.2/tg | No description available  
1.2/M | No description available  
1.2/Mg | No description available  
1.2/Mq | No description available  
1.2/Mr 1.2/t0 | No description available  
1.2/NF | No description available  
1.2/NM | No description available  
1.2/Np 1.2/t7 | No description available  
1.2/R | No description available  
1.2/TB | No description available  
1.2/Y 1.2/ta | No description available  
1.2/a | No description available  
  

> volume #1.1.1.1 style surface

> transparency 50

ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  

> select clear

Chain HM, residue 1 specifies more than one residue! The simulation can still
run, but this will probably cause problems later if not rectified by
renumbering.  

Deleted the following atoms from residue FAD FD1: H1'', H8M2, H6A2, H8M1,
H7M2, H3, H5B1, HO2B, H5', HO3B, H5'', H1, H7M3, H1', H7M1, H6A1, H5B2, H8M3  

> isolde ignore #1/FS

ISOLDE: currently ignoring 3 residues in model 1.2  

> isolde ignore #1/HM

ISOLDE: currently ignoring 6 residues in model 1.2  

> isolde ignore #1/HN

ISOLDE: currently ignoring 8 residues in model 1.2  

> isolde ignore #1/HO

ISOLDE: currently ignoring 9 residues in model 1.2  
Fetching CCD CYS_LEO2_DHG from http://ligand-
expo.rcsb.org/reports/C/CYS_LEO2_DHG/CYS_LEO2_DHG.cif  
Fetching CCD CSO from
https://files.wwpdb.org/pub/pdb/refdata/chem_comp/O/CSO/CSO.cif  
Fetching CCD CSS from
https://files.wwpdb.org/pub/pdb/refdata/chem_comp/S/CSS/CSS.cif  

Chain HM, residue 1 specifies more than one residue! The simulation can still
run, but this will probably cause problems later if not rectified by
renumbering.  

> save "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV1.cif"

Not saving entity_poly_seq for non-authoritative sequences  

Cannot save '/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV1.cif':
[Errno 60] Operation timed out  

> save "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV2.cxs"

> save "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV2.cif"

Not saving entity_poly_seq for non-authoritative sequences  

> select
> ~#3/Ks,te,Iy,tc,Ix,t9,Kp,Il,td,JJ,t6,Mr,t0,K5,I0,tb,JI,Lr,Y,ta,NF,Mx,J6,t1,CS,NM,LY,tg,JN,tf,L3,M,J4,LR,Jx,Jw,t8,Ar,t4,Mw,Lb,AG,t3,KI,t5,Ii,Ke,Mh,LO,t2,Mq,TB,Ml,Mg,LG,MC,Np,t7,I2&#3

Nothing selected  

> select
> ~#1/Ks,te,Iy,tc,Ix,t9,Kp,Il,td,JJ,t6,Mr,t0,K5,I0,tb,JI,Lr,Y,ta,NF,Mx,J6,t1,CS,NM,LY,tg,JN,tf,L3,M,J4,LR,Jx,Jw,t8,Ar,t4,Mw,Lb,AG,t3,KI,t5,Ii,Ke,Mh,LO,t2,Mq,TB,Ml,Mg,LG,MC,Np,t7,I2&#1

124014 atoms, 125318 bonds, 32 pseudobonds, 7825 residues, 18 models selected  

> select
> #1/Ks,te,Iy,tc,Ix,t9,Kp,Il,td,JJ,t6,Mr,t0,K5,I0,tb,JI,Lr,Y,ta,NF,Mx,J6,t1,CS,NM,LY,tg,JN,tf,L3,M,J4,LR,Jx,Jw,t8,Ar,t4,Mw,Lb,AG,t3,KI,t5,Ii,Ke,Mh,LO,t2,Mq,TB,Ml,Mg,LG,MC,Np,t7,I2

145655 atoms, 147751 bonds, 11 pseudobonds, 8830 residues, 2 models selected  

> select #1

269669 atoms, 273069 bonds, 43 pseudobonds, 16655 residues, 19 models selected  

> select
> ~#1/Ks,te,Iy,tc,Ix,t9,Kp,Il,td,JJ,t6,Mr,t0,K5,I0,tb,JI,Lr,Y,ta,NF,Mx,J6,t1,CS,NM,LY,tg,JN,tf,L3,M,J4,LR,Jx,Jw,t8,Ar,t4,Mw,Lb,AG,t3,KI,t5,Ii,Ke,Mh,LO,t2,Mq,TB,Ml,Mg,LG,MC,Np,t7,I2&#1

124014 atoms, 125318 bonds, 32 pseudobonds, 7825 residues, 19 models selected  

> select up

269669 atoms, 273069 bonds, 43 pseudobonds, 16655 residues, 18 models selected  

> select down

124014 atoms, 125318 bonds, 32 pseudobonds, 7825 residues, 19 models selected  

> select
> #1/Ks,te,Iy,tc,Ix,t9,Kp,Il,td,JJ,t6,Mr,t0,K5,I0,tb,JI,Lr,Y,ta,NF,Mx,J6,t1,CS,NM,LY,tg,JN,tf,L3,M,J4,LR,Jx,Jw,t8,Ar,t4,Mw,Lb,AG,t3,KI,t5,Ii,Ke,Mh,LO,t2,Mq,TB,Ml,Mg,LG,MC,Np,t7,I2

145655 atoms, 147751 bonds, 11 pseudobonds, 8830 residues, 2 models selected  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp.mrc"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #2, grid size
500,500,500, pixel 1.21, shown at level 0.118, step 2, values float32  

> hide #!2 models

> select
> ~#1/Ks,te,Iy,tc,Ix,t9,Kp,Il,td,JJ,t6,Mr,t0,K5,I0,tb,JI,Lr,Y,ta,NF,Mx,J6,t1,CS,NM,LY,tg,JN,tf,L3,M,J4,LR,Jx,Jw,t8,Ar,t4,Mw,Lb,AG,t3,KI,t5,Ii,Ke,Mh,LO,t2,Mq,TB,Ml,Mg,LG,MC,Np,t7,I2&#1

124014 atoms, 125318 bonds, 32 pseudobonds, 7825 residues, 20 models selected  

> save "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV2.cxs"

> isolde sim start /R,A-A0,AU-Aq,B-F9,FF-FO,Fy-Fz,IE-IY,JC,a,GT-HM,FS,FD,HN-HO

ISOLDE: started sim  

> show #!2 models

> show sel cartoons

> hide sel atoms

> hide #!2 models

> select clear

> select up

74 atoms, 75 bonds, 4 residues, 1 model selected  

> select up

2235 atoms, 2273 bonds, 140 residues, 1 model selected  

> show sel atoms

> hide sel cartoons

> show sel cartoons

> hide sel atoms

> select up

59 atoms, 58 bonds, 4 residues, 1 model selected  

> select up

5332 atoms, 5377 bonds, 324 residues, 1 model selected  

> show sel atoms

> hide sel atoms

> select up

101 atoms, 100 bonds, 6 residues, 1 model selected  

> select up

2362 atoms, 2389 bonds, 148 residues, 1 model selected  

> show sel atoms

> hide sel atoms

> select
> ~#1/Ks,te,Iy,tc,Ix,t9,Kp,Il,td,JJ,t6,Mr,t0,K5,I0,tb,JI,Lr,Y,ta,NF,Mx,J6,t1,CS,NM,LY,tg,JN,tf,L3,M,J4,LR,Jx,Jw,t8,Ar,t4,Mw,Lb,AG,t3,KI,t5,Ii,Ke,Mh,LO,t2,Mq,TB,Ml,Mg,LG,MC,Np,t7,I2&#1

124014 atoms, 125318 bonds, 32 pseudobonds, 7825 residues, 23 models selected  

> show #!2 models

> hide #!2 models

> select clear

> select up

54 atoms, 54 bonds, 3 residues, 1 model selected  

> select up

1424 atoms, 1442 bonds, 88 residues, 1 model selected  

> show sel atoms

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 359 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start /GT

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 3 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> show #!2 models

> transparency 0

> transparency 50

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ.cif"

Summary of feedback from opening
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ.cif  
---  
warnings | Missing entity information. Treating each chain as a separate entity.  
Missing or incomplete sequence information. Inferred polymer connectivity.  
  
  
Chain information for cryosparc_P43_J450_008_volume_map_sharp_NOSEQ.cif #3  
---  
Chain | Description  
1 CY | No description available  
3 | No description available  
6 | No description available  
8 | No description available  
9 Au | No description available  
A | No description available  
A3 DB | No description available  
A4 | No description available  
A6 | No description available  
A8 | No description available  
A9 | No description available  
AA | No description available  
AB | No description available  
AD | No description available  
AE | No description available  
AF | No description available  
AG AJ EH | No description available  
AH | No description available  
AK | No description available  
AL | No description available  
AN Fo | No description available  
AO | No description available  
AP | No description available  
AQ | No description available  
AR BH DP EC | No description available  
AS CS | No description available  
AV | No description available  
AZ Bz CJ CP CZ Cr t | No description available  
Aa | No description available  
Ab | No description available  
Ad | No description available  
Ae | No description available  
Am M | No description available  
An | No description available  
Ao | No description available  
Aq | No description available  
Ar | No description available  
As BB Bn | No description available  
Ax | No description available  
Ay BK | No description available  
Az | No description available  
B1 | No description available  
B2 | No description available  
B3 | No description available  
B5 | No description available  
B9 | No description available  
BC EV | No description available  
BJ | No description available  
BL | No description available  
BO | No description available  
BP | No description available  
BQ | No description available  
BW | No description available  
BY C u | No description available  
Bb o | No description available  
Bd | No description available  
Bf | No description available  
Bg Ce | No description available  
Bp | No description available  
Bq | No description available  
Bt | No description available  
Bv | No description available  
Bw | No description available  
By w | No description available  
C2 | No description available  
C3 | No description available  
C4 | No description available  
C7 | No description available  
CA | No description available  
CE Ca | No description available  
CG | No description available  
CQ p | No description available  
CR | No description available  
Cg EY | No description available  
Cv | No description available  
Cz | No description available  
D | No description available  
D3 | No description available  
DI | No description available  
DZ | No description available  
Di | No description available  
Dr | No description available  
E | No description available  
E0 | No description available  
E1 | No description available  
E2 | No description available  
E3 | No description available  
E4 | No description available  
E5 | No description available  
E6 | No description available  
E7 | No description available  
E8 | No description available  
E9 | No description available  
EJ | No description available  
EK | No description available  
Ec | No description available  
Ef | No description available  
Eg | No description available  
Eh | No description available  
Ei | No description available  
Ej | No description available  
Ek | No description available  
El | No description available  
Em | No description available  
En | No description available  
Eo | No description available  
Ep | No description available  
Eq | No description available  
Er | No description available  
Es | No description available  
Et | No description available  
Eu | No description available  
Ev | No description available  
Ew | No description available  
Ex | No description available  
Ey | No description available  
Ez | No description available  
F0 | No description available  
F1 | No description available  
F2 Fq | No description available  
F3 | No description available  
F4 | No description available  
F5 | No description available  
F6 | No description available  
F7 | No description available  
F8 | No description available  
F9 | No description available  
FA | No description available  
FB | No description available  
FC | No description available  
FD | No description available  
FE | No description available  
FF | No description available  
FG | No description available  
FH | No description available  
FI | No description available  
FJ | No description available  
FK | No description available  
FL | No description available  
FM | No description available  
FN | No description available  
FO | No description available  
FP | No description available  
FQ | No description available  
FR | No description available  
FS | No description available  
FT | No description available  
FU | No description available  
FV | No description available  
FW | No description available  
FX | No description available  
FY | No description available  
FZ | No description available  
Fa | No description available  
Fb | No description available  
Fc | No description available  
Fd | No description available  
Fe | No description available  
Ff GH | No description available  
Fg | No description available  
Fh | No description available  
Fi | No description available  
Fj | No description available  
Fk | No description available  
Fl | No description available  
Fm | No description available  
Fn | No description available  
Fp | No description available  
Fr | No description available  
Fs | No description available  
Ft | No description available  
Fu | No description available  
Fv | No description available  
Fw | No description available  
Fx | No description available  
Fy | No description available  
Fz | No description available  
G X | No description available  
GA | No description available  
GB | No description available  
GC | No description available  
GD | No description available  
GE | No description available  
GF | No description available  
GG | No description available  
GI | No description available  
GJ | No description available  
GK | No description available  
GL | No description available  
GM | No description available  
GN | No description available  
GO | No description available  
GP | No description available  
GQ | No description available  
GR | No description available  
GS | No description available  
GT | No description available  
J | No description available  
L | No description available  
N | No description available  
O | No description available  
P | No description available  
Q | No description available  
R | No description available  
S | No description available  
T | No description available  
U | No description available  
V | No description available  
W | No description available  
Y | No description available  
Z | No description available  
a | No description available  
c | No description available  
d | No description available  
e | No description available  
g | No description available  
h | No description available  
i | No description available  
j | No description available  
l | No description available  
m | No description available  
n | No description available  
q | No description available  
r | No description available  
v | No description available  
x | No description available  
y | No description available  
  

> select #3

26819 atoms, 27073 bonds, 3296 residues, 1 model selected  

> hide sel atoms

> show sel cartoons

Computing secondary structure  

> color #3@C* lawngreen

> hide #!2 models

> select clear

> select up

20 atoms, 20 bonds, 1 residue, 2 models selected  

> select up

278 atoms, 283 bonds, 17 residues, 2 models selected  

> select up

876 atoms, 889 bonds, 57 residues, 2 models selected  

> isolde sim start #1.2/E1:51-123

ISOLDE: started sim  

> show sel cartoons

> hide sel atoms

> ui mousemode right "isolde tug selection"

> select up

416 atoms, 419 bonds, 28 residues, 1 model selected  

> select clear

> show sel atoms

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 3 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/FO:12-31

ISOLDE: started sim  

> ui mousemode right "isolde tug selection"

> show sel cartoons

> ui mousemode right "isolde tug atom"

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/FO:69-106

ISOLDE: started sim  

> show sel cartoons

> ui mousemode right "isolde tug selection"

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select clear

> isolde sim start #1.2/Ek:73-79

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select clear

> select #3

26819 atoms, 27073 bonds, 3296 residues, 1 model selected  

> select clear

> select up

19 atoms, 18 bonds, 1 residue, 1 model selected  

> select up

308 atoms, 312 bonds, 20 residues, 2 models selected  

> select up

1301 atoms, 1326 bonds, 78 residues, 2 models selected  

> select up

269669 atoms, 273069 bonds, 16655 residues, 2 models selected  

> hide sel atoms

> select up

68 atoms, 68 bonds, 4 residues, 1 model selected  

> select up

1301 atoms, 1326 bonds, 78 residues, 1 model selected  

> isolde sim start #1.2/Ek

ISOLDE: started sim  

> select #3

26819 atoms, 27073 bonds, 3296 residues, 1 model selected  

> show sel cartoons

[Repeated 4 time(s)]

> isolde sim stop discardTo start

Sim termination reason: None  
reverting to start  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> select up

68 atoms, 68 bonds, 4 residues, 1 model selected  

> isolde sim start #1.2/Ek:41-44

ISOLDE: started sim  

> show sel atoms

> show sel cartoons

> hide sel cartoons

> select up

520 atoms, 528 bonds, 30 residues, 2 models selected  

> select up

1301 atoms, 1326 bonds, 78 residues, 2 models selected  

> select up

269669 atoms, 273069 bonds, 16655 residues, 2 models selected  

> isolde sim stop discardTo start

Sim termination reason: None  
reverting to start  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> select #1/Ek

1301 atoms, 1326 bonds, 78 residues, 1 model selected  

> isolde sim start #1.2/Ek

ISOLDE: started sim  

> show sel cartoons

> select clear

> select up

68 atoms, 68 bonds, 4 residues, 1 model selected  

> ui mousemode right "isolde tug selection"

> select ~sel & ##selected

269657 atoms, 273058 bonds, 43 pseudobonds, 16654 residues, 3 models selected  

> select #1/Ek

1301 atoms, 1326 bonds, 78 residues, 1 model selected  

> show sel atoms

> select clear

> ui mousemode right "isolde tug atom"

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 14 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select up

101 atoms, 101 bonds, 7 residues, 1 model selected  

> isolde sim start #1.2/Ev:26-32

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> select #1/Ek

1301 atoms, 1326 bonds, 78 residues, 1 model selected  

> isolde sim start #1.2/Ek

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

> ui mousemode right "isolde tug selection"

> select clear

> ui mousemode right "isolde tug atom"

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 6 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select #1/Ek

1301 atoms, 1326 bonds, 78 residues, 1 model selected  

> volume #1.1.1.1 level 0.4677

> select up

290 atoms, 293 bonds, 17 residues, 1 model selected  

> select #1/R

1050 atoms, 1074 bonds, 62 residues, 1 model selected  

> isolde sim start #1.2/R

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

> ui mousemode right "isolde tug selection"

> ui mousemode right "isolde tug atom"

> select #1

269669 atoms, 273069 bonds, 43 pseudobonds, 16655 residues, 23 models selected  

> show sel cartoons

> select up

49 atoms, 49 bonds, 3 residues, 1 model selected  

> select up

2235 atoms, 2273 bonds, 140 residues, 1 model selected  

> select down

49 atoms, 49 bonds, 3 residues, 1 model selected  

> ui mousemode right "isolde tug selection"

> select clear

> ui mousemode right "isolde tug residue"

> isolde sim stop discardTo start

Sim termination reason: None  
reverting to start  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> select up

73 atoms, 76 bonds, 4 residues, 1 model selected  

> select up

2235 atoms, 2273 bonds, 140 residues, 1 model selected  

> isolde sim start #1.2/FH

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

> hide sel atoms

> ui mousemode right "isolde tug selection"

> show sel atoms

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 4 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select #1/Ek

1301 atoms, 1326 bonds, 78 residues, 1 model selected  

> isolde sim start #1.2/R:1-5

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

> ui mousemode right "isolde tug selection"

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select #1/Ek

1301 atoms, 1326 bonds, 78 residues, 1 model selected  

> isolde sim start #1.2/Ek

ISOLDE: started sim  

> isolde sim stop discardTo start

Sim termination reason: None  
reverting to start  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> select #1/R

1050 atoms, 1074 bonds, 62 residues, 1 model selected  

> isolde sim start #1.2/R

ISOLDE: started sim  

> show sel atoms

> show sel cartoons

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 6 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select #1/R

1050 atoms, 1074 bonds, 62 residues, 1 model selected  

> isolde sim start #1.2/R

ISOLDE: started sim  

> show sel atoms

> show sel cartoons

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 5 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> save "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV3.cxs"

> select #1/Es

2211 atoms, 2250 bonds, 135 residues, 1 model selected  

> isolde sim start #1.2/Es

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 11 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select clear

> select up

180 atoms, 181 bonds, 10 residues, 1 model selected  

> select up

6250 atoms, 6346 bonds, 384 residues, 1 model selected  

> select down

180 atoms, 181 bonds, 10 residues, 1 model selected  

> select up

6250 atoms, 6346 bonds, 384 residues, 1 model selected  

> isolde sim start #1.2/Ev

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 2 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 8 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select #1/Es

2211 atoms, 2250 bonds, 135 residues, 1 model selected  

> isolde sim start #1.2/Es

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

> select clear

> select #1/Es

2211 atoms, 2250 bonds, 135 residues, 1 model selected  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 6 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 19 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select #1/Fy

946 atoms, 957 bonds, 58 residues, 1 model selected  

> isolde sim start #1.2/Fy

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 2 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 3 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select #1/FO

2362 atoms, 2389 bonds, 148 residues, 1 model selected  

> isolde sim start #1.2/FO

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> hide sel atoms

> ui mousemode right "isolde tug residue"

> show sel atoms

> ui mousemode right "isolde tug atom"

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 18 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select #1/GT

1424 atoms, 1442 bonds, 88 residues, 1 model selected  

> isolde sim start #1.2/GT

ISOLDE: started sim  

> show sel atoms

> show sel cartoons

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde cisflip #1.2/GT:72

[Repeated 3 time(s)]

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 2 time(s)]

> select #1/GT

1424 atoms, 1442 bonds, 88 residues, 1 model selected  

> select clear

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 11 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select up

96 atoms, 95 bonds, 6 residues, 1 model selected  

> select up

1424 atoms, 1442 bonds, 88 residues, 1 model selected  

> isolde sim start #1.2/GT

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select #1/GT

1424 atoms, 1442 bonds, 88 residues, 1 model selected  

> select #1/E4

2790 atoms, 2822 bonds, 169 residues, 1 model selected  

> isolde sim start #1.2/E4

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 9 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select clear

> select #1/FH

2235 atoms, 2273 bonds, 140 residues, 1 model selected  

> isolde sim start #1.2/FH

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 3 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 6 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select clear

> select #1/GT,Ek,R,Es,Fy,FO,GT,E4,FH

14319 atoms, 14533 bonds, 878 residues, 1 model selected  

> color sel&@C* magenta

> select clear

> hide #3 models

> show #3 models

> color #1/GT,Ek,R,Es,Fy,FO,GT,E4,FH,Ev@C* magenta

> select #1/A

5332 atoms, 5377 bonds, 324 residues, 1 model selected  

> color #1/GT,Ek,R,Es,Fy,FO,GT,E4,FH,Ev,A@C* magenta

> select #1/F9

1174 atoms, 1200 bonds, 67 residues, 1 model selected  

> color #1/GT,Ek,R,Es,Fy,FO,GT,E4,FH,Ev,A,F9@C* magenta

> select clear

> select #1/Eq

1501 atoms, 1534 bonds, 84 residues, 1 model selected  

> isolde sim start #1.2/Eq

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

> isolde sim stop discardTo start

Sim termination reason: None  
reverting to start  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Eq

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> show sel cartoons

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 15 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> color #1/GT,Ek,R,Es,Fy,FO,GT,E4,FH,Ev,A,F9,Eq@C* magenta

> select #1/E1

1237 atoms, 1254 bonds, 1 pseudobond, 80 residues, 2 models selected  

> isolde sim start #1.2/E1

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> hide #3 models

> color #1/GT,Ek,R,Es,Fy,FO,GT,E4,FH,Ev,A,F9,Eq,E1@C* magenta

> select #1/a

1583 atoms, 1606 bonds, 94 residues, 1 model selected  

> show #3 models

> isolde sim start #1.2/a

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde cisflip #1.2/a:62

[Repeated 1 time(s)]

> isolde cisflip #1.2/a:63

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 7 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select #1/a

1583 atoms, 1606 bonds, 94 residues, 1 model selected  

> color #1/GT,Ek,R,Es,Fy,FO,GT,E4,FH,Ev,A,F9,Eq,E1,a@C* magenta

> select clear

> color #1/GT,Ek,R,Es,Fy,FO,GT,E4,FH,Ev,A,F9,Eq,E1,a@C* magenta

> select #1/a

1583 atoms, 1606 bonds, 94 residues, 1 model selected  

> hide #3 models

> select clear

> show #3 models

> select #1/Fz

798 atoms, 808 bonds, 48 residues, 1 model selected  

> isolde sim start #1.2/Fz

ISOLDE: started sim  

> show sel atoms

> show sel cartoons

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> color #1/GT,Ek,R,Es,Fy,FO,GT,E4,FH,Ev,A,F9,Eq,E1,a,Fz@C* magenta

> hide #3 models

> select clear

> select #1/FL

4007 atoms, 4077 bonds, 233 residues, 1 model selected  

> isolde sim start #1.2/FL

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

> show #3 models

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 13 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select clear

> color #1/GT,Ek,R,Es,Fy,FO,GT,E4,FH,Ev,A,F9,Eq,E1,a,Fz,FL@C* magenta

> select #1/FL

4007 atoms, 4077 bonds, 233 residues, 1 model selected  

> hide #3 models

> select clear

> volume #1.1.1.1 level 0.2554

> show #!2 models

> show #3 models

> hide #3 models

> hide #!2 models

> show #3 models

> select up

341 atoms, 345 bonds, 21 residues, 1 model selected  

> select up

361 atoms, 365 bonds, 23 residues, 1 model selected  

> select down

341 atoms, 345 bonds, 21 residues, 1 model selected  

> select down

17 atoms, 1 residue, 1 model selected  

> select up

341 atoms, 345 bonds, 21 residues, 1 model selected  

> isolde sim start #1.2/E1:218-238

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> select #1

269669 atoms, 273069 bonds, 43 pseudobonds, 16655 residues, 23 models selected  

> show sel cartoons

> hide sel cartoons

> select #1/FL

4007 atoms, 4077 bonds, 233 residues, 1 model selected  

> show sel atoms

> hide sel atoms

> select #1/E1

1237 atoms, 1254 bonds, 1 pseudobond, 80 residues, 2 models selected  

> show sel cartoons

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/E1

ISOLDE: started sim  

> show sel cartoons

> show sel atoms

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select #1

269669 atoms, 273069 bonds, 43 pseudobonds, 16655 residues, 23 models selected  

> show sel atoms

> select up

24 atoms, 23 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/E1:238

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> select #1/Fy

946 atoms, 957 bonds, 58 residues, 1 model selected  

> isolde sim start #1.2/Fy

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> hide #3 models

> select clear

> select #1/FF

1189 atoms, 1211 bonds, 1 pseudobond, 72 residues, 2 models selected  

> isolde sim start #1.2/FF

ISOLDE: started sim  

> show sel cartoons

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 3 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> color #1/GT,Ek,R,Es,Fy,FO,GT,E4,FH,Ev,A,F9,Eq,E1,a,Fz,FL,FF@C* magenta

> select clear

> show #!2 models

> ui tool show "Ramachandran Plot"

> select #1/GT,Ek,R,Es,Fy,FO,GT,E4,FH,Ev,A,F9,Eq,E1,a,Fz,FL,FF

37390 atoms, 37946 bonds, 2 pseudobonds, 2264 residues, 2 models selected  

> isolde sim start #1.2/IY:198

ISOLDE: started sim  

> hide #!2 models

> isolde pepflip #1.2/IY:198

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/A:88

ISOLDE: started sim  

> isolde pepflip #1.2/A:88

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/R:57

ISOLDE: started sim  

> isolde pepflip #1.2/R:57

[Repeated 1 time(s)]

> isolde pepflip #1.2/R:58

> isolde pepflip #1.2/R:56

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/B:96

ISOLDE: started sim  

> isolde pepflip #1.2/B:96

> isolde pepflip #1.2/B:97

[Repeated 3 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/B:54

ISOLDE: started sim  

> isolde pepflip #1.2/B:54

> isolde pepflip #1.2/B:53

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/C7:69

ISOLDE: started sim  

> isolde pepflip #1.2/C7:69

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Eq:71

ISOLDE: started sim  

> isolde pepflip #1.2/Eq:72

> isolde pepflip #1.2/Eq:73

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Ek:72

ISOLDE: started sim  

> isolde pepflip #1.2/Ek:72

> isolde cisflip #1.2/Ek:71

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Ek:74

ISOLDE: started sim  

> isolde pepflip #1.2/Ek:74

[Repeated 2 time(s)]

> isolde pepflip #1.2/Ek:75

> isolde pepflip #1.2/Ek:74

[Repeated 3 time(s)]

> isolde pepflip #1.2/Ek:73

> isolde pepflip #1.2/Ek:74

[Repeated 1 time(s)]

> isolde pepflip #1.2/Ek:73

> isolde pepflip #1.2/Ek:74

> isolde pepflip #1.2/Ek:75

[Repeated 1 time(s)]

> select clear

> isolde pepflip #1.2/Ek:74

> isolde pepflip #1.2/Ek:75

[Repeated 4 time(s)]

> isolde pepflip #1.2/Ek:74

[Repeated 1 time(s)]

> isolde pepflip #1.2/Ek:73

[Repeated 1 time(s)]

> isolde pepflip #1.2/Ek:74

[Repeated 1 time(s)]

> isolde pepflip #1.2/Ek:75

[Repeated 1 time(s)]

> isolde pepflip #1.2/Ek:76

[Repeated 3 time(s)]

> select up

7 atoms, 6 bonds, 1 residue, 2 models selected  

> select up

308 atoms, 312 bonds, 20 residues, 2 models selected  

> select up

1301 atoms, 1326 bonds, 78 residues, 2 models selected  

> isolde pepflip #1.2/Ek:75

> isolde pepflip #1.2/Ek:76

> isolde pepflip #1.2/Ek:74

> isolde pepflip #1.2/Ek:75

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> show #3 models

> hide #3 models

> isolde sim start #1.2/D:131

ISOLDE: started sim  

> isolde pepflip #1.2/D:131

> isolde pepflip #1.2/D:130

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/F9:100

ISOLDE: started sim  

> isolde pepflip #1.2/F9:101

[Repeated 1 time(s)]

> isolde pepflip #1.2/F9:102

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/FO:113

ISOLDE: started sim  

> isolde pepflip #1.2/FO:113

> isolde pepflip #1.2/FO:111

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/E1:233

ISOLDE: started sim  

> isolde pepflip #1.2/E1:233

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/C:310

ISOLDE: started sim  

> isolde pepflip #1.2/C:310

> isolde pepflip #1.2/C:311

[Repeated 1 time(s)]

> isolde pepflip #1.2/C:310

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/A:285

ISOLDE: started sim  

> isolde pepflip #1.2/A:288

> isolde pepflip #1.2/A:289

[Repeated 1 time(s)]

> isolde cisflip #1.2/A:288

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/IE:172

ISOLDE: started sim  

> isolde pepflip #1.2/IE:172

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/BK:133

ISOLDE: started sim  

> isolde pepflip #1.2/BK:133

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Ek:27

ISOLDE: started sim  

> isolde pepflip #1.2/Ek:27

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Eq:136

ISOLDE: started sim  

> isolde pepflip #1.2/Eq:136

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/E4:191

ISOLDE: started sim  

> isolde pepflip #1.2/E4:191

> isolde pepflip #1.2/E4:190

[Repeated 2 time(s)]

> isolde pepflip #1.2/E4:188

[Repeated 1 time(s)]

> isolde pepflip #1.2/E4:187

[Repeated 3 time(s)]

> isolde pepflip #1.2/E4:188

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Ab:484

ISOLDE: started sim  

> isolde pepflip #1.2/Ab:484

> isolde pepflip #1.2/Ab:483

> isolde pepflip #1.2/Ab:482

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Aq:64

ISOLDE: started sim  

> isolde pepflip #1.2/Aq:64

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/E4:37

ISOLDE: started sim  

> isolde pepflip #1.2/E4:37

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/AU:198

ISOLDE: started sim  

> isolde pepflip #1.2/AU:198

[Repeated 2 time(s)]

> isolde pepflip #1.2/AU:199

> isolde pepflip #1.2/AU:200

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/FL:8

ISOLDE: started sim  

> isolde pepflip #1.2/FL:8

> isolde pepflip #1.2/FL:9

> isolde pepflip #1.2/FL:8

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/FL:9

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Fz:86

ISOLDE: started sim  

> isolde pepflip #1.2/Fz:87

> isolde pepflip #1.2/Fz:88

[Repeated 3 time(s)]

> isolde pepflip #1.2/Fz:87

> isolde pepflip #1.2/Fz:86

[Repeated 1 time(s)]

> select clear

> isolde pepflip #1.2/Fz:82

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/A0:592

ISOLDE: started sim  

> select clear

> isolde pepflip #1.2/A0:592

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/D:240

ISOLDE: started sim  

> isolde pepflip #1.2/D:240

> isolde pepflip #1.2/D:239

[Repeated 1 time(s)]

> isolde pepflip #1.2/D:240

[Repeated 1 time(s)]

> isolde pepflip #1.2/D:239

> isolde pepflip #1.2/D:238

[Repeated 2 time(s)]

> isolde pepflip #1.2/D:240

> isolde pepflip #1.2/D:241

> select clear

> isolde pepflip #1.2/D:239

[Repeated 3 time(s)]

> isolde pepflip #1.2/D:238

> isolde pepflip #1.2/D:239

> isolde pepflip #1.2/D:238

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 3 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> save "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV4.cxs"

Taking snapshot of stepper: superComplexConsolidatedV1.cif  

> isolde sim start #1.2/D:55

ISOLDE: started sim  

> select clear

> isolde pepflip #1.2/D:55

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/C:339

ISOLDE: started sim  

> isolde pepflip #1.2/C:339

[Repeated 1 time(s)]

> isolde pepflip #1.2/C:338

> isolde pepflip #1.2/C:339

[Repeated 1 time(s)]

> isolde pepflip #1.2/C:340

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Fz:80

ISOLDE: started sim  

> isolde pepflip #1.2/Fz:80

[Repeated 3 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/AU:235

ISOLDE: started sim  

> isolde pepflip #1.2/AU:235

[Repeated 2 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> cd "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation"

Current working directory is:
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation  

> save "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV4.cxs"

Taking snapshot of stepper: superComplexConsolidatedV1.cif  

> runscript /Users/rafaelrocha/Library/CloudStorage/OneDrive-
> Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py

Traceback (most recent call last):  
File "/Users/rafaelrocha/Library/CloudStorage/OneDrive-
Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py", line 12, in <module>  
rootPath = sys.argv[1]  
~~~~~~~~^^^  
IndexError: list index out of range  
  
Error opening python file /Users/rafaelrocha/Library/CloudStorage/OneDrive-
Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py  

> runscript /Users/rafaelrocha/Library/CloudStorage/OneDrive-
> Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py ./

Traceback (most recent call last):  
File "/Users/rafaelrocha/Library/CloudStorage/OneDrive-
Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py", line 17, in <module>  
from RAMOptimization import *  
ModuleNotFoundError: No module named 'RAMOptimization'  
  
Error opening python file /Users/rafaelrocha/Library/CloudStorage/OneDrive-
Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py  

> runscript /Users/rafaelrocha/Library/CloudStorage/OneDrive-
> Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py ./

Traceback (most recent call last):  
File "/Users/rafaelrocha/Library/CloudStorage/OneDrive-
Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py", line 17, in <module>  
from RAMOptimization import *  
ModuleNotFoundError: No module named 'RAMOptimization'  
  
Error opening python file /Users/rafaelrocha/Library/CloudStorage/OneDrive-
Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py  

> runscript /Users/rafaelrocha/Library/CloudStorage/OneDrive-
> Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py ./

Traceback (most recent call last):  
File "/Users/rafaelrocha/Library/CloudStorage/OneDrive-
Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py", line 17, in <module>  
from RAMOptimization import *  
ModuleNotFoundError: No module named 'RAMOptimization'  
  
Error opening python file /Users/rafaelrocha/Library/CloudStorage/OneDrive-
Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py  

> runscript /Users/rafaelrocha/Library/CloudStorage/OneDrive-
> Personal/GitHub/KRSPs/isoldeScripts/RAMOptimization.py ./

Traceback (most recent call last):  
File "/Users/rafaelrocha/Library/CloudStorage/OneDrive-
Personal/GitHub/KRSPs/isoldeScripts/RAMOptimization.py", line 12, in <module>  
from get_Data import *  
ModuleNotFoundError: No module named 'get_Data'  
  
Error opening python file /Users/rafaelrocha/Library/CloudStorage/OneDrive-
Personal/GitHub/KRSPs/isoldeScripts/RAMOptimization.py  

> runscript /Users/rafaelrocha/Library/CloudStorage/OneDrive-
> Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py ./

Traceback (most recent call last):  
File "/Users/rafaelrocha/Library/CloudStorage/OneDrive-
Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py", line 17, in <module>  
from RAMOptimization import *  
ModuleNotFoundError: No module named 'RAMOptimization'  
  
Error opening python file /Users/rafaelrocha/Library/CloudStorage/OneDrive-
Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py  

> runscript /Users/rafaelrocha/Library/CloudStorage/OneDrive-
> Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py ./

Traceback (most recent call last):  
File "/Users/rafaelrocha/Library/CloudStorage/OneDrive-
Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py", line 17, in <module>  
from RAMOptimization import *  
ModuleNotFoundError: No module named 'RAMOptimization'  
  
Error opening python file /Users/rafaelrocha/Library/CloudStorage/OneDrive-
Personal/GitHub/KRSPs/isoldeScripts/runOptimization.py  

> isolde pepflip #1.2/B:144

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/A:281

ISOLDE: started sim  

> isolde pepflip #1.2/A:281

[Repeated 4 time(s)]

> isolde pepflip #1.2/A:280

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Es:132

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/BP:108

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Ab:273

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/C0:74

ISOLDE: started sim  

> isolde pepflip #1.2/C0:74

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/C0:39

ISOLDE: started sim  

> isolde pepflip #1.2/C0:39

[Repeated 1 time(s)]

> isolde pepflip #1.2/C0:38

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/B:60

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A:93

ISOLDE: started sim  

> isolde pepflip #1.2/A:93

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/D:243

ISOLDE: started sim  

> isolde pepflip #1.2/D:243

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Ev:226

ISOLDE: started sim  

> select clear

> isolde pepflip #1.2/Ev:227

> select clear

> isolde pepflip #1.2/Ev:228

Unable to flip peptide bond after 50 rounds. Giving up.  

> isolde pepflip #1.2/Ev:228

> isolde cisflip #1.2/Ev:228

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Ab:307

ISOLDE: started sim  

> isolde pepflip #1.2/Ab:307

> isolde pepflip #1.2/Ab:306

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/D6:42

ISOLDE: started sim  

> isolde pepflip #1.2/D6:41

[Repeated 1 time(s)]

> isolde pepflip #1.2/D6:42

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/BI:92

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/E:539

ISOLDE: started sim  

> isolde pepflip #1.2/E:538

> isolde pepflip #1.2/E:539

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/GT:91

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/AU:313

ISOLDE: started sim  

> isolde pepflip #1.2/AU:312

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A0:309

ISOLDE: started sim  

> isolde pepflip #1.2/A0:309

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/B:41

ISOLDE: started sim  

> select clear

> isolde pepflip #1.2/B:41

> isolde pepflip #1.2/B:42

[Repeated 1 time(s)]

> isolde pepflip #1.2/B:41

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/R:6

ISOLDE: started sim  

> isolde pepflip #1.2/R:7

> isolde cisflip #1.2/R:8

> isolde pepflip #1.2/R:7

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Ek:59

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/A:135

ISOLDE: started sim  

> isolde cisflip #1.2/A:134

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/C8:34

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/BK:343

ISOLDE: started sim  

> isolde pepflip #1.2/BK:344

[Repeated 2 time(s)]

> isolde cisflip #1.2/BK:342

[Repeated 1 time(s)]

> isolde pepflip #1.2/BK:342

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> select clear

> isolde pepflip #1.2/BK:344

[Repeated 1 time(s)]

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/BK:342

> isolde pepflip #1.2/BK:344

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Aj:668

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/E4:202

ISOLDE: started sim  

> isolde pepflip #1.2/E4:202

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Ev:359

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Aj:228

ISOLDE: started sim  

> isolde pepflip #1.2/Aj:229

> isolde pepflip #1.2/Aj:228

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/FO:82

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/FO:76

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/a:61

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Aj:332

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/B:44

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Es:113

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/IE:169

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/AU:548

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/FO:131

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Es:74

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/C2:39

ISOLDE: started sim  

> isolde pepflip #1.2/C2:39

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/C2:38

ISOLDE: started sim  

> isolde pepflip #1.2/C2:38

[Repeated 1 time(s)]

> select clear

> isolde pepflip #1.2/C2:39

> select clear

> isolde pepflip #1.2/C2:40

> isolde pepflip #1.2/C2:41

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/IY:81

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/A0:519

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/R:3

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/GT:81

ISOLDE: started sim  

> isolde pepflip #1.2/GT:75

> isolde pepflip #1.2/GT:76

[Repeated 1 time(s)]

> isolde pepflip #1.2/GT:75

[Repeated 1 time(s)]

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/GT:75

> isolde pepflip #1.2/GT:77

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Es:99

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/D:91

ISOLDE: started sim  

> isolde pepflip #1.2/D:91

[Repeated 2 time(s)]

> isolde pepflip #1.2/D:89

[Repeated 1 time(s)]

> isolde pepflip #1.2/D:91

> isolde pepflip #1.2/D:94

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Aj:275

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/FL:40

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/E:452

ISOLDE: started sim  

> isolde pepflip #1.2/E:451

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/AU:506

ISOLDE: started sim  

> isolde pepflip #1.2/AU:506

[Repeated 2 time(s)]

> isolde pepflip #1.2/AU:507

> isolde pepflip #1.2/AU:506

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/D:252

ISOLDE: started sim  

> isolde pepflip #1.2/D:253

> isolde pepflip #1.2/D:254

> isolde pepflip #1.2/D:250

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/D:50

ISOLDE: started sim  

> isolde pepflip #1.2/D:49

> isolde pepflip #1.2/D:52

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/E1:56

ISOLDE: started sim  

> isolde pepflip #1.2/E1:57

[Repeated 1 time(s)]

> isolde pepflip #1.2/E1:58

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/E1:58

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/E1:58

ISOLDE: started sim  

> isolde pepflip #1.2/E1:58

[Repeated 1 time(s)]

> isolde pepflip #1.2/E1:59

[Repeated 1 time(s)]

> isolde pepflip #1.2/E1:60

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Es:107

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/JC:54

ISOLDE: started sim  

> isolde pepflip #1.2/JC:55

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/IY:46

ISOLDE: started sim  

> isolde pepflip #1.2/IY:46

[Repeated 4 time(s)]

> isolde pepflip #1.2/IY:44

[Repeated 1 time(s)]

> isolde pepflip #1.2/IY:43

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/IE:96

ISOLDE: started sim  

> isolde pepflip #1.2/IE:95

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/D:134

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/D:135

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/BK:391

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Aq:131

ISOLDE: started sim  

> isolde pepflip #1.2/Aq:130

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/IY:165

ISOLDE: started sim  

> select clear

> isolde pepflip #1.2/IY:166

> isolde pepflip #1.2/IY:164

[Repeated 1 time(s)]

> isolde pepflip #1.2/IY:166

> isolde pepflip #1.2/IY:164

> isolde pepflip #1.2/IY:166

[Repeated 2 time(s)]

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/IY:165

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/E4:178

ISOLDE: started sim  

> isolde pepflip #1.2/E4:178

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/IY:120

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Es:43

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/a:74

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/AU:359

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Ev:32

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/AU:391

ISOLDE: started sim  

> isolde cisflip #1.2/AU:390

[Repeated 2 time(s)]

> isolde pepflip #1.2/AU:389

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/AU:386

ISOLDE: started sim  

> isolde pepflip #1.2/AU:386

> isolde pepflip #1.2/AU:387

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/D6:11

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/IE:115

ISOLDE: started sim  

> isolde pepflip #1.2/IE:116

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/JC:181

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/FO:79

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Ab:663

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/t3:100

ISOLDE: started sim  

> isolde pepflip #1.2/t3:100

> isolde sim stop discardTo start

Sim termination reason: None  
reverting to start  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/E:361

ISOLDE: started sim  

> isolde pepflip #1.2/E:361

[Repeated 1 time(s)]

> isolde pepflip #1.2/E:362

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Es:18

ISOLDE: started sim  

> isolde pepflip #1.2/Es:18

> isolde pepflip #1.2/Es:19

[Repeated 1 time(s)]

> isolde pepflip #1.2/Es:18

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/AU:401

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/a:71

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Es:22

ISOLDE: started sim  

> isolde pepflip #1.2/Es:23

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/D:187

ISOLDE: started sim  

> isolde pepflip #1.2/D:187

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Ab:368

ISOLDE: started sim  

> isolde pepflip #1.2/Ab:369

[Repeated 2 time(s)]

> isolde pepflip #1.2/Ab:368

> isolde pepflip #1.2/Ab:370

[Repeated 1 time(s)]

> isolde pepflip #1.2/Ab:371

[Repeated 2 time(s)]

> isolde pepflip #1.2/Ab:369

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/Ab:367

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 3 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/A0:482

ISOLDE: started sim  

> isolde pepflip #1.2/A0:483

[Repeated 1 time(s)]

> isolde pepflip #1.2/A0:484

> isolde pepflip #1.2/A0:482

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/FL:76

ISOLDE: started sim  

> isolde pepflip #1.2/FL:76

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/E4:187

ISOLDE: started sim  

> isolde pepflip #1.2/E4:188

[Repeated 1 time(s)]

> isolde pepflip #1.2/E4:187

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/E4:107

ISOLDE: started sim  

> isolde pepflip #1.2/E4:107

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/FL:75

ISOLDE: started sim  

> isolde pepflip #1.2/FL:75

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/FO:71

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/C:305

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Ab:312

ISOLDE: started sim  

> isolde pepflip #1.2/Ab:312

> isolde pepflip #1.2/Ab:313

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A0:254

ISOLDE: started sim  

> isolde pepflip #1.2/A0:254

[Repeated 1 time(s)]Unable to flip peptide bond after 50 rounds. Giving up.  

> isolde pepflip #1.2/A0:254

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/GT:10

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/C:273

ISOLDE: started sim  

> isolde pepflip #1.2/C:273

> isolde pepflip #1.2/C:274

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/C:273

> isolde pepflip #1.2/C:274

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/JC:30

ISOLDE: started sim  

> isolde pepflip #1.2/JC:30

> isolde pepflip #1.2/JC:31

> isolde pepflip #1.2/JC:32

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/C5:35

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/BK:72

ISOLDE: started sim  

> isolde pepflip #1.2/BK:72

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Aj:221

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/BK:40

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Aj:320

ISOLDE: started sim  

> isolde pepflip #1.2/Aj:320

> isolde pepflip #1.2/Aj:322

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/FF:125

ISOLDE: started sim  

> isolde pepflip #1.2/FF:128

> isolde pepflip #1.2/FF:127

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Ab:254

ISOLDE: started sim  

> isolde pepflip #1.2/Ab:254

> isolde pepflip #1.2/Ab:255

> isolde pepflip #1.2/Ab:254

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Ab:217

ISOLDE: started sim  

> select clear

[Repeated 1 time(s)]

> isolde pepflip #1.2/Ab:218

[Repeated 1 time(s)]

> isolde pepflip #1.2/Ab:215

[Repeated 3 time(s)]Unable to flip peptide bond after 50 rounds. Giving up.  

> isolde pepflip #1.2/Ab:215

[Repeated 1 time(s)]

> isolde pepflip #1.2/Ab:213

> isolde pepflip #1.2/Ab:214

> isolde pepflip #1.2/AU:87

> isolde pepflip #1.2/Ab:216

> isolde pepflip #1.2/Ab:215

[Repeated 4 time(s)]

> isolde pepflip #1.2/Ab:216

[Repeated 1 time(s)]

> isolde pepflip #1.2/Ab:215

[Repeated 1 time(s)]

> isolde pepflip #1.2/Ab:216

[Repeated 1 time(s)]

> isolde pepflip #1.2/Ab:214

> isolde pepflip #1.2/Ab:215

[Repeated 4 time(s)]

> isolde pepflip #1.2/Ab:216

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Ab:562

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/JC:92

ISOLDE: started sim  

> isolde pepflip #1.2/JC:92

> isolde pepflip #1.2/JC:93

> isolde cisflip #1.2/JC:93

> isolde pepflip #1.2/JC:93

Unable to flip peptide bond after 50 rounds. Giving up.  

> isolde cisflip #1.2/JC:93

> isolde pepflip #1.2/JC:92

[Repeated 1 time(s)]

> isolde pepflip #1.2/JC:93

Unable to flip peptide bond after 50 rounds. Giving up.  

> isolde cisflip #1.2/JC:95

[Repeated 1 time(s)]

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/JC:95

> isolde cisflip #1.2/JC:93

> isolde pepflip #1.2/JC:92

[Repeated 1 time(s)]

> isolde cisflip #1.2/JC:93

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/JC:23

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/A0:348

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/A:324

ISOLDE: started sim  

> select clear

> isolde pepflip #1.2/A:324

> isolde pepflip #1.2/A:325

Unable to flip peptide bond after 50 rounds. Giving up.  

> isolde cisflip #1.2/A:325

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/GT:71

ISOLDE: started sim  

> isolde cisflip #1.2/GT:72

> isolde pepflip #1.2/GT:72

Unable to flip peptide bond after 50 rounds. Giving up.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/E4:101

ISOLDE: started sim  

> isolde cisflip #1.2/E4:102

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/B:71

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/BK:59

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Es:123

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/E4:193

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/FO:119

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/E1:64

ISOLDE: started sim  

> isolde cisflip #1.2/E1:65

[Repeated 1 time(s)]

> isolde pepflip #1.2/E1:64

> isolde pepflip #1.2/E1:62

> isolde pepflip #1.2/E1:63

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/GT:76

ISOLDE: started sim  

> isolde pepflip #1.2/GT:75

> isolde pepflip #1.2/GT:74

> isolde pepflip #1.2/GT:76

[Repeated 1 time(s)]

> isolde pepflip #1.2/GT:77

> isolde pepflip #1.2/GT:76

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/GT:71

ISOLDE: started sim  

> isolde pepflip #1.2/GT:72

Unable to flip peptide bond after 50 rounds. Giving up.  

> isolde pepflip #1.2/GT:72

Unable to flip peptide bond after 50 rounds. Giving up.  

> isolde cisflip #1.2/GT:72

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/GT:76

ISOLDE: started sim  

> isolde pepflip #1.2/GT:76

[Repeated 2 time(s)]

> isolde pepflip #1.2/GT:75

> isolde pepflip #1.2/GT:73

> isolde pepflip #1.2/GT:74

> isolde pepflip #1.2/GT:76

[Repeated 3 time(s)]

> isolde pepflip #1.2/GT:73

[Repeated 2 time(s)]

> isolde pepflip #1.2/GT:74

> isolde pepflip #1.2/GT:73

[Repeated 2 time(s)]

> isolde pepflip #1.2/GT:75

> isolde pepflip #1.2/GT:79

> isolde pepflip #1.2/GT:76

> isolde pepflip #1.2/GT:77

[Repeated 1 time(s)]

> isolde pepflip #1.2/GT:76

> isolde pepflip #1.2/GT:75

[Repeated 1 time(s)]

> select clear

> isolde pepflip #1.2/GT:76

> isolde pepflip #1.2/GT:74

> isolde pepflip #1.2/GT:76

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/C:92

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/A:256

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/FO:117

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/AU:87

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Es:5

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/K5:31

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/A0:219

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/E:344

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/FO:41

ISOLDE: started sim  

> isolde pepflip #1.2/FO:41

> isolde pepflip #1.2/FO:42

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Aj:283

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/C8:37

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/JC:112

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/AU:500

ISOLDE: started sim  

> isolde pepflip #1.2/AU:501

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/Aj:353

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/IY:62

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/B:57

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/D:173

ISOLDE: started sim  

> isolde pepflip #1.2/D:174

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/C:326

ISOLDE: started sim  

> isolde pepflip #1.2/C:326

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde pepflip #1.2/IY:179

ISOLDE: started sim  

> select clear

> isolde pepflip #1.2/IY:179

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/E:118

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/IY:176

ISOLDE: started sim  

> isolde cisflip #1.2/IY:176

[Repeated 1 time(s)]

> isolde pepflip #1.2/IY:177

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/C1:72

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Eq:131

ISOLDE: started sim  

> isolde pepflip #1.2/Eq:132

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/C4:72

ISOLDE: started sim  

> isolde pepflip #1.2/C4:74

> isolde pepflip #1.2/C4:75

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/E:60

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Aj:516

ISOLDE: started sim  

> isolde pepflip #1.2/Aj:517

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/A:166

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/FF:100

ISOLDE: started sim  

> isolde pepflip #1.2/FF:101

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/JC:65

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Aj:231

ISOLDE: started sim  

> isolde pepflip #1.2/Aj:230

> isolde pepflip #1.2/Aj:231

Unable to flip peptide bond after 50 rounds. Giving up.  

> isolde cisflip #1.2/Aj:231

> select clear

> isolde pepflip #1.2/Aj:231

Unable to flip peptide bond after 50 rounds. Giving up.  

> isolde pepflip #1.2/Aj:231

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Ab:656

ISOLDE: started sim  

> isolde cisflip #1.2/Ab:656

> isolde pepflip #1.2/Ab:656

Unable to flip peptide bond after 50 rounds. Giving up.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/D:43

ISOLDE: started sim  

> isolde cisflip #1.2/D:43

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/E1:65

ISOLDE: started sim  

> isolde cisflip #1.2/E1:65

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/FL:85

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 4 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/C0:35

ISOLDE: started sim  

> isolde sim stop discardTo start

Sim termination reason: None  
reverting to start  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/C0:35

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/C0:41

ISOLDE: started sim  

> isolde pepflip #1.2/C0:41

[Repeated 1 time(s)]

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 4 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/BK:40

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/BK:40

ISOLDE: started sim  

> isolde pepflip #1.2/BK:106

[Repeated 1 time(s)]

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 4 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Aq:132

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 2 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Aq:154

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A0:206

ISOLDE: started sim  

> isolde pepflip #1.2/A0:207

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Ev:265

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Ab:427

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Eq:68

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 12 time(s)]

> isolde pepflip #1.2/FL:76

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A:300

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 3 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/R:44

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 3 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 5 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/BK:295

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/FO:127

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 2 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/C:169

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde pepflip #1.2/C:169

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/E4:154

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 5 time(s)]

> isolde pepflip #1.2/E4:154

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/IY:210

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 4 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/C1:65

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 6 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Es:93

ISOLDE: started sim  

> isolde pepflip #1.2/Es:85

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/te:38

ISOLDE: started sim  

> select up

22 atoms, 21 bonds, 1 residue, 1 model selected  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Fz:86

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 4 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 3 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Es:110

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/JC:106

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 7 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/K5:52

ISOLDE: started sim  

> isolde sim pause

> select up

22 atoms, 21 bonds, 1 residue, 1 model selected  

> ui mousemode right "translate selected atoms"

> isolde sim resume

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/E:484

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/IY:126

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/IY:75

ISOLDE: started sim  

> isolde pepflip #1.2/IY:75

> isolde pepflip #1.2/IY:76

[Repeated 2 time(s)]

> isolde cisflip #1.2/IY:73

> isolde pepflip #1.2/Ab:596

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/A:272

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/BI:45

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/FO:78

ISOLDE: started sim  

> isolde pepflip #1.2/FO:80

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A0:514

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A0:370

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Fy:106

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Ab:464

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/D:240

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/D:238

ISOLDE: started sim  

> isolde pepflip #1.2/D:238

[Repeated 1 time(s)]

> isolde pepflip #1.2/D:239

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/C3:66

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/C3:72

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Eq:93

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/FL:14

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Ab:213

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/E1:238

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/E4:125

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/FF:124

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/BP:103

ISOLDE: started sim  

> isolde pepflip #1.2/BP:101

> isolde pepflip #1.2/BP:104

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/BP:102

[Repeated 1 time(s)]

> select clear

> isolde pepflip #1.2/BP:101

[Repeated 1 time(s)]

> isolde pepflip #1.2/BP:100

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 3 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/GT:62

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/C6:103

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/FO:104

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A0:518

ISOLDE: started sim  

> isolde pepflip #1.2/A0:518

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/C4:48

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A0:247

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/E4:182

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/E:539

ISOLDE: started sim  

> isolde pepflip #1.2/E:539

> isolde pepflip #1.2/E:540

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/C7:98

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/BK:515

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/AU:205

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/IY:198

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde pepflip #1.2/JC:87

> isolde pepflip #1.2/JC:86

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/AU:235

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/C1:33

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/D:48

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/E:83

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A:104

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 2 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/C:253

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/C2:43

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/C2:42

> isolde pepflip #1.2/C2:40

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 1 time(s)]

> select clear

[Repeated 1 time(s)]

> isolde pepflip #1.2/C2:41

[Repeated 1 time(s)]

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/C2:42

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/AU:226

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/AU:548

ISOLDE: started sim  

> isolde pepflip #1.2/AU:548

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Fy:84

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/JC:154

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 2 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/E:527

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 2 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/FF:167

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/D:179

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Ab:500

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/BK:287

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A:257

ISOLDE: started sim  

> isolde pepflip #1.2/A:257

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 5 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/BK:417

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/E1:64

ISOLDE: started sim  

> isolde cisflip #1.2/E1:66

[Repeated 1 time(s)]

> isolde cisflip #1.2/E1:67

> isolde cisflip #1.2/E1:66

> isolde cisflip #1.2/E1:65

> isolde pepflip #1.2/E1:64

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/t2:106

ISOLDE: started sim  

> select up

15 atoms, 14 bonds, 1 residue, 2 models selected  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/AU:572

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A0:339

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/FH:58

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A:142

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A:135

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/BK:439

ISOLDE: started sim  

> isolde pepflip #1.2/BK:438

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/D:37

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/AU:91

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/IE:118

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/A:249

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Aj:567

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/E1:117

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/Fz:98

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/E:44

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/BK:572

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/B:83

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/C:152

ISOLDE: started sim  

> isolde pepflip #1.2/C:153

[Repeated 1 time(s)]

> isolde pepflip #1.2/C:152

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/C:293

ISOLDE: started sim  

> isolde pepflip #1.2/C:294

[Repeated 1 time(s)]

> isolde pepflip #1.2/C:291

[Repeated 2 time(s)]

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/C:291

[Repeated 2 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/B:75

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/D6:12

ISOLDE: started sim  

> isolde pepflip #1.2/D6:10

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Ab:455

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde pepflip #1.2/FH:35

ISOLDE: started sim  

> select clear

> isolde pepflip #1.2/FH:35

> isolde pepflip #1.2/FH:34

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/C9:57

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/FF:102

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/AU:111

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/AU:38

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/BI:102

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/E1:106

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/AU:327

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/A:118

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Eq:124

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/FL:219

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/R:31

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Ek:87

ISOLDE: started sim  

> isolde pepflip #1.2/Ek:88

> isolde pepflip #1.2/Ek:89

> isolde pepflip #1.2/Ek:88

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/Ek:87

[Repeated 1 time(s)]

> isolde pepflip #1.2/Ek:90

> isolde pepflip #1.2/Ek:91

> isolde pepflip #1.2/Ek:90

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 2 time(s)]

> isolde pepflip #1.2/Ek:88

[Repeated 2 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/E1:114

ISOLDE: started sim  

> isolde pepflip #1.2/E1:115

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/E1:122

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A0:550

ISOLDE: started sim  

> isolde pepflip #1.2/A0:552

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/E1:115

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/BK:539

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/R:20

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A0:440

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/E:59

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Es:123

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Aj:674

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A:85

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/BK:447

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/BI:110

ISOLDE: started sim  

> isolde pepflip #1.2/BI:110

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/A0:658

ISOLDE: started sim  

> isolde pepflip #1.2/A0:658

[Repeated 1 time(s)]

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> save "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV5.cxs"

Taking snapshot of stepper: superComplexConsolidatedV1.cif  

> show #!2 models

> volume #2 step 1

> volume #2 level 0.1727

> hide #!2 models

> show #3 models

> hide #!1 models

> show #!2 models

> volume #2 level 0.296

> show #!1 models

> molmap #1

Missing or invalid "resolution" argument: Expected a number  

> molmap #1 resolution 3.5

Missing or invalid "resolution" argument: Expected a number  

> molmap #1 3.5

Opened superComplexConsolidatedV1.cif map 3.5 as #4, grid size 226,226,275,
pixel 1.17, shown at level 0.106, step 1, values float32  

> volume subtract #4 #1

Opened volume difference as #5, grid size 226,226,275, pixel 1.17, shown at
step 1, values float32  

> hide #3 models

> hide #!2 models

> hide #!1 models

> close #5

> show #!1 models

> volume subtract #1 #4

Opened volume difference as #5, grid size 500,500,500, pixel 1.21, shown at
step 1, values float32  

> show #3 models

> addligand

Unknown command: isolde addligand  

> isolde add ligand P5S

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> select #!

Expected an objects specifier or a keyword  

> select #1

269805 atoms, 273204 bonds, 43 pseudobonds, 16656 residues, 23 models selected  

> select up

136 atoms, 135 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/Eq:1000

Sim termination reason: None  
ISOLDE: stopped sim  

Chain HM, residue 1 specifies more than one residue! The simulation can still
run, but this will probably cause problems later if not rectified by
renumbering.  

> isolde replace ligand #1/Eq:1000 3PE

Deleted the following atoms from residue P5S Eq1000: OXT, O, C, HXT  

129 atoms were automatically renamed to match the template: P12->P, O15->O12,
HO15->H1, O16->O11, C3->C1, C1->C3, O19->O31, C17->C31, C20->C32, C21->C33,
C22->C34, C23->C35, C24->C36, C25->C37, C26->C38, C27->C39, C28->C3A,
C29->C3B, C30->C3C, C31->C3D, C32->C3E, C33->C3F, C34->C3G, C35->C3H,
C36->C3I, O37->O21, C38->C21, C39->C22, C40->C23, C41->C24, C42->C25,
C43->C26, C44->C27, C45->C28, C46->C29, C48->C2A, C49->C2B, C50->C2C,
C51->C2D, C52->C2E, C53->C2F, C54->C2G, C55->C2H, C56->C2I, O18->O32,
O47->O22, OG->O13, CB->C11, CA->C12, O13->O14, H1->H31, H1A->H32, H20->H321,
H20A->H322, H21->H331, H21A->H332, H22->H341, H22A->H342, H23->H351,
H23A->H352, H24->H361, H24A->H362, H25->H371, H25A->H372, H26->H381,
H26A->H382, H27->H391, H27A->H392, H28->H3A1, H28A->H3A2, H29->H3B1,
H29A->H3B2, H3->H11, H3A->H12, H30->H3C1, H30A->H3C2, H31->H3D1, H31A->H3D2,
H32->H3E1, H32A->H3E2, H33->H3F1, H33A->H3F2, H34->H3G1, H34A->H3G2,
H35->H3H1, H35A->H3H2, H39->H221, H39A->H222, H40->H231, H40A->H232,
H41->H241, H41A->H242, H42->H251, H42A->H252, H43->H261, H43A->H262,
H44->H271, H44A->H272, H45->H281, H45A->H282, H46->H291, H46A->H292,
H48->H2A1, H48A->H2A2, H49->H2B1, H49A->H2B2, H50->H2C1, H50A->H2C2,
H51->H2D1, H51A->H2D2, H52->H2E1, H52A->H2E2, H53->H2F1, H53A->H2F2,
H54->H2G1, H54A->H2G2, H55->H2H1, H55A->H2H2, HA->H121, HB->H111, HBA->H112,
HN->HN1, HNA->HN2, H36->H3I1, H36A->H3I2, H36B->H3I3, H56->H2I1, H56A->H2I2,
H56B->H2I3  

Deleted the following atoms from residue 3PE Eq1000: H1  
Traceback (most recent call last):  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/cmd_line/tool.py", line 319, in execute  
cmd.run(cmd_text)  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/commands/cli.py", line 3213, in run  
result = ci.function(session, **kw_args)  
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^  
File "/Users/rafaelrocha/Library/Application
Support/ChimeraX/1.9/lib/python/site-
packages/chimerax/isolde/atomic/building/cmd.py", line 47, in replace_residue  
chiral_centers = Atoms([a for a in residue.atoms if
residue.ideal_chirality(a.name) != 'N'])  
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^  
File "/Users/rafaelrocha/Library/Application
Support/ChimeraX/1.9/lib/python/site-
packages/chimerax/isolde/atomic/building/cmd.py", line 47, in <listcomp>  
chiral_centers = Atoms([a for a in residue.atoms if
residue.ideal_chirality(a.name) != 'N'])  
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/atomic/molobject.py", line 659, in ideal_chirality  
return f(self.name.encode('utf-8'), atom_name.encode('utf-8'))  
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^  
KeyError: 'Atom HN3 not in mmCIF Chemical Component Dictionary for 3PE'  
  
KeyError: 'Atom HN3 not in mmCIF Chemical Component Dictionary for 3PE'  
  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/atomic/molobject.py", line 659, in ideal_chirality  
return f(self.name.encode('utf-8'), atom_name.encode('utf-8'))  
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^  
  
See log for complete Python traceback.  
  

> delete #1/Eq:1000

> isolde add ligand P5S

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> delete #1/Eq:1000

> isolde add ligand 3PE

Deleted the following atoms from residue 3PE Eq1000: H1  

> select up

133 atoms, 132 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/Eq:1000

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> select up

133 atoms, 132 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/Eq:1000

ISOLDE: started sim  

> hide #!5 models

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde replace ligand #1/Eq:1000 P5S

Deleted the following atoms from residue 3PE Eq1000: H122, H4  

128 atoms were automatically renamed to match the template: C12->CA, C11->CB,
O13->OG, P->P12, H111->HB, H112->HBA, H121->HA, O11->O16, C1->C3, C3->C1,
O21->O37, C21->C38, C22->C39, C23->C40, C24->C41, C25->C42, C26->C43,
C27->C44, C28->C45, C29->C46, C2A->C48, C2B->C49, C2C->C50, C2D->C51,
C2E->C52, C2F->C53, C2G->C54, C2H->C55, C2I->C56, O31->O19, C31->C17,
C32->C20, C33->C21, C34->C22, C35->C23, C36->C24, C37->C25, C38->C26,
C39->C27, C3A->C28, C3B->C29, C3C->C30, C3D->C31, C3E->C32, C3F->C33,
C3G->C34, C3H->C35, C3I->C36, O22->O47, O32->O18, H11->H3, H12->H3A,
H221->H39, H222->H39A, H231->H40, H232->H40A, H241->H41, H242->H41A,
H251->H42, H252->H42A, H261->H43, H262->H43A, H271->H44, H272->H44A,
H281->H45, H282->H45A, H291->H46, H292->H46A, H2A1->H48, H2A2->H48A,
H2B1->H49, H2B2->H49A, H2C1->H50, H2C2->H50A, H2D1->H51, H2D2->H51A,
H2E1->H52, H2E2->H52A, H2F1->H53, H2F2->H53A, H2G1->H54, H2G2->H54A,
H2H1->H55, H2H2->H55A, H31->H1, H32->H1A, H321->H20, H322->H20A, H331->H21,
H332->H21A, H341->H22, H342->H22A, H351->H23, H352->H23A, H361->H24,
H362->H24A, H371->H25, H372->H25A, H381->H26, H382->H26A, H391->H27,
H392->H27A, H3A1->H28, H3A2->H28A, H3B1->H29, H3B2->H29A, H3C1->H30,
H3C2->H30A, H3D1->H31, H3D2->H31A, H3E1->H32, H3E2->H32A, H3F1->H33,
H3F2->H33A, H3G1->H34, H3G2->H34A, H3H1->H35, H3H2->H35A, O12->O15, O14->O13,
H2I1->H56, H2I2->H56A, H2I3->H56B, H3I1->H36, H3I2->H36A, H3I3->H36B, HN3->HN,
H3->HNA  

Rebuilt ligand P5S has chiral centres at atoms CA,C2 (highlighted). Since the
current algorithm used to match topologies is not chirality aware, you should
check these sites carefully to ensure they are sensible. If in doubt, it is
best to delete with "del #1.2/Eq:1000" and replace with "isolde add ligand
P5S".  

> select up

136 atoms, 135 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/Eq:1000

Sim termination reason: None  
ISOLDE: stopped sim  
Traceback (most recent call last):  
File "/Users/rafaelrocha/Library/Application
Support/ChimeraX/1.9/lib/python/site-
packages/chimerax/isolde/ui/validation_tab/unparameterised.py", line 160, in
_table_item_clicked_cb  
residue.atoms.displays = True  
^^^^^^^^^^^^^  
File "atomic_cpp/cymol.pyx", line 1033, in
chimerax.atomic.cymol.CyResidue.atoms.__get__  
RuntimeError: Residue already deleted  
  
RuntimeError: Residue already deleted  
  
File "atomic_cpp/cymol.pyx", line 1033, in
chimerax.atomic.cymol.CyResidue.atoms.__get__  
  
See log for complete Python traceback.  
  

> delete #1/Eq:1000

> isolde add ligand P5S

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> select up

136 atoms, 135 bonds, 1 residue, 1 model selected  

Chain HM, residue 1 specifies more than one residue! The simulation can still
run, but this will probably cause problems later if not rectified by
renumbering.  

> save "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV5.cxs"

Taking snapshot of stepper: superComplexConsolidatedV1.cif  

——— End of log from Wed Jan 15 18:04:27 2025 ———

opened ChimeraX session  

> select up

136 atoms, 135 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/Eq:1000

Sim termination reason: None  
ISOLDE: stopped sim  
Loading residue template for 3PE from internal database  
Loading residue template for ATP from internal database  
Loading residue template for FAD from internal database  
Loading residue template for LPP from internal database  
Loading residue template for PC1 from internal database  

Chain HM, residue 1 specifies more than one residue! The simulation can still
run, but this will probably cause problems later if not rectified by
renumbering.  

> isolde parameterise sel override false

Running ANTECHAMBER command:
/Applications/ChimeraX-1.9.app/Contents/bin/amber20/bin/antechamber -ek
qm_theory='AM1', -i
/var/folders/6k/vqtllq5921g_007bj4yyl62c0000gn/T/tmp44xcpvsk/ante.in.mol2 -fi
mol2 -o
/var/folders/6k/vqtllq5921g_007bj4yyl62c0000gn/T/tmp44xcpvsk/ante.out.mol2 -fo
mol2 -c bcc -nc 0 -j 5 -s 2 -dr n  
(P5S) ``  
(P5S) `Welcome to antechamber 20.0: molecular input file processor.`  
(P5S) ``  
(P5S) `Info: Finished reading file
(/var/folders/6k/vqtllq5921g_007bj4yyl62c0000gn/T/tmp44xcpvsk/ante.in.mol2);
atoms read (136), bonds read (135).`  
(P5S) `Info: Determining atomic numbers from atomic symbols which are case
sensitive.`  
(P5S) `Running:
/Applications/ChimeraX-1.9.app/Contents/bin/amber20/bin/bondtype -j part -i
ANTECHAMBER_BOND_TYPE.AC0 -o ANTECHAMBER_BOND_TYPE.AC -f ac`  
(P5S) ``  
(P5S) ``  
(P5S) `Running:
/Applications/ChimeraX-1.9.app/Contents/bin/amber20/bin/atomtype -i
ANTECHAMBER_AC.AC0 -o ANTECHAMBER_AC.AC -p gaff`  
(P5S) `Info: Total number of electrons: 436; net charge: 0`  
(P5S) ``  
(P5S) `Running: /Applications/ChimeraX-1.9.app/Contents/bin/amber20/bin/sqm -O
-i sqm.in -o sqm.out`  
(P5S) ``  
(P5S) `Running: /Applications/ChimeraX-1.9.app/Contents/bin/amber20/bin/am1bcc
-i ANTECHAMBER_AM1BCC_PRE.AC -o ANTECHAMBER_AM1BCC.AC -f ac -p
/Applications/ChimeraX-1.9.app/Contents/bin/amber20/dat/antechamber/BCCPARM.DAT
-s 2 -j 1`  
(P5S) ``  
(P5S) `Running:
/Applications/ChimeraX-1.9.app/Contents/bin/amber20/bin/atomtype -f ac -p bcc
-o ANTECHAMBER_AM1BCC.AC -i ANTECHAMBER_AM1BCC_PRE.AC`  
(P5S) ``  
Charges for residue P5S determined  
OpenMM ffXML file P5S written to the current working directory.  
New template added to forcefield as USER_P5S. This ligand should now work in
all remaining simulations for this session. To use in future sessions, load
the ffXML file with ISOLDE's Load Residue MD Definition(s) button.  

> isolde sim start #1.2/Eq:1000

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

[Repeated 3 time(s)]

> isolde sim stop discardTo start

Sim termination reason: None  
reverting to start  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> delete #1/Eq:1000

> isolde add ligand PC1

> isolde sim start #1.2/E4:1000

ISOLDE: started sim  

> show #!5 models

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> hide #!5 models

> save /Users/rafaelrocha/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV6.cxs

Taking snapshot of stepper: superComplexConsolidatedV1.cif  

——— End of log from Wed Jan 15 18:19:59 2025 ———

opened ChimeraX session  

> select up

269811 atoms, 273210 bonds, 16656 residues, 7 models selected  

> ui tool show "Volume Viewer"

> select clear

> volume #1.1.1.1 level 0.1808

> show #!5 models

> hide #!5 models

> volume #1.1.1.1 level 0.2064

> delete #1/Eq:1000

> delete #1/E4:1000

> isolde add ligand CDL

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/E4:1000

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> show #!5 models

> transparency #5.1#1.1.1.1.1 0

> transparency #5.1#1.1.1.1.1 50

> transparency #5.1#1.1.1.1.1 0

> transparency #5.1#1.1.1.1.1 50

> volume #5 level 0.2465

> volume #5 level 0.2197

> hide #!1.1 models

> show #!1.1 models

> hide #3 models

> hide #!1.1 models

> show #!1.1 models

> hide #!1.2 models

> show #!1.2 models

> isolde add ligand CDL

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> select up

3302 atoms, 3332 bonds, 171 residues, 1 model selected  

> select clear

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/E4:1001

ISOLDE: started sim  

> hide #!1.2 models

> show #!1.2 models

> hide #!1.1 models

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde add ligand CDL

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/E4:1002

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> hide #!1.2 models

> show #!1.2 models

> select #1

270437 atoms, 273834 bonds, 43 pseudobonds, 16658 residues, 29 models selected  

> hide sel cartoons

> hide sel atoms

> select #1&ligand

4801 atoms, 4820 bonds, 38 residues, 1 model selected  

> show sel cartoons

> show sel atoms

> isolde add ligand CDL

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/FL:1000

ISOLDE: started sim  

> show #!1.1 models

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> volume #1.1.1.1 level 0.335

> select #1

270693 atoms, 274089 bonds, 43 pseudobonds, 16659 residues, 29 models selected  

> show sel cartoons

> show sel atoms

> hide sel atoms

> isolde add ligand CDL

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> show sel cartoons

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> delete #1/E4:1003

> select #1&ligand

5057 atoms, 5075 bonds, 39 residues, 1 model selected  

> show sel cartoons

> show sel atoms

> isolde add ligand PC1

Loading residue template for PC1 from internal database  

> select up

142 atoms, 141 bonds, 1 residue, 1 model selected  

> ui mousemode right "translate selected atoms"

> select #1

270835 atoms, 274230 bonds, 43 pseudobonds, 16660 residues, 29 models selected  

> select up

142 atoms, 141 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/E4:1003

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> select #1

270835 atoms, 274230 bonds, 43 pseudobonds, 16660 residues, 29 models selected  

> hide sel cartoons

> select #1@H*

135705 atoms, 16654 residues, 1 model selected  

> hide sel atoms

> volume #5 level 0.2113

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/E4:1000

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> select #1

270835 atoms, 274230 bonds, 43 pseudobonds, 16660 residues, 29 models selected  

> show sel cartoons

> show sel atoms

> select up

270835 atoms, 274230 bonds, 43 pseudobonds, 16660 residues, 29 models selected  

> select up

20 atoms, 20 bonds, 1 residue, 2 models selected  

> select up

97 atoms, 98 bonds, 5 residues, 2 models selected  

> isolde sim start #1.2/a:35-39

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde add ligand PC1

> select up

142 atoms, 141 bonds, 1 residue, 1 model selected  

> ui mousemode right "translate selected atoms"

> select #1@H*

135793 atoms, 16655 residues, 1 model selected  

> hide sel atoms

> select #1

270977 atoms, 274371 bonds, 43 pseudobonds, 16661 residues, 29 models selected  

> select up

142 atoms, 141 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/a:1000

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> select #1

270977 atoms, 274371 bonds, 43 pseudobonds, 16661 residues, 29 models selected  

> hide sel atoms

> hide sel cartoons

> select #1&ligand

5341 atoms, 5357 bonds, 41 residues, 1 model selected  

> show sel atoms

> select #1@H*

135793 atoms, 16655 residues, 1 model selected  

> hide sel atoms

> select #1

270977 atoms, 274371 bonds, 43 pseudobonds, 16661 residues, 29 models selected  

> isolde add ligand CDL

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/Eq:1000

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> select #1

271233 atoms, 274626 bonds, 43 pseudobonds, 16662 residues, 29 models selected  

> show sel cartoons

> show sel atoms

> hide sel cartoons

> hide sel atoms

> select #1&ligand

5597 atoms, 5612 bonds, 42 residues, 1 model selected  

> show sel cartoons

> show sel atoms

> select #1@H*

135949 atoms, 16656 residues, 1 model selected  

> hide sel atoms

> select #1

271233 atoms, 274626 bonds, 43 pseudobonds, 16662 residues, 29 models selected  

> isolde add ligand CDL

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/Es:1000

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde sim start #1.2/Eq:1000

ISOLDE: started sim  

> select clear

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde add ligand CDL

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/a:1001

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde add ligand PC1

> isolde sim start #1.2/FL,a:1001

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> select #1

271887 atoms, 275277 bonds, 43 pseudobonds, 16665 residues, 29 models selected  

> show sel cartoons

> show sel atoms

> select up

19 atoms, 18 bonds, 1 residue, 2 models selected  

> select up

201 atoms, 203 bonds, 12 residues, 2 models selected  

> isolde sim start #1.2/FL:69-80

ISOLDE: started sim  

> ui tool show "Ramachandran Plot"

> isolde pepflip #1.2/FL:71

[Repeated 2 time(s)]

> isolde pepflip #1.2/FL:70

[Repeated 1 time(s)]

> isolde pepflip #1.2/FL:72

[Repeated 1 time(s)]

> isolde pepflip #1.2/FL:71

[Repeated 3 time(s)]

> isolde pepflip #1.2/FL:70

> isolde pepflip #1.2/FL:72

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> select up

16 atoms, 15 bonds, 1 residue, 2 models selected  

> select up

201 atoms, 203 bonds, 12 residues, 2 models selected  

> select #1@H*

136349 atoms, 16659 residues, 1 model selected  

> hide sel atoms

> select up

142 atoms, 141 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/FL:1001

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> select #1

271887 atoms, 275277 bonds, 43 pseudobonds, 16665 residues, 29 models selected  

> hide sel atoms

> show sel cartoons

> hide sel cartoons

> select #1&ligand

6251 atoms, 6263 bonds, 45 residues, 1 model selected  

> show sel cartoons

> show sel atoms

> select #1@H*

136349 atoms, 16659 residues, 1 model selected  

> hide sel atoms

> select #1

271887 atoms, 275277 bonds, 43 pseudobonds, 16665 residues, 29 models selected  

> show sel atoms

> show sel cartoons

> hide sel atoms

> hide sel cartoons

> select #1&ligand

6251 atoms, 6263 bonds, 45 residues, 1 model selected  

> show sel atoms

> select #1@H*

136349 atoms, 16659 residues, 1 model selected  

> hide sel atoms

> isolde add ligand CDL

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/E1:1000

ISOLDE: started sim  

> select #1

272143 atoms, 275532 bonds, 43 pseudobonds, 16666 residues, 29 models selected  

> show sel cartoons

> show sel atoms

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> select up

19 atoms, 18 bonds, 1 residue, 1 model selected  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 1 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select #1

272143 atoms, 275532 bonds, 43 pseudobonds, 16666 residues, 29 models selected  

> show sel cartoons

> show sel atoms

> select up

19 atoms, 18 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/E1:99

ISOLDE: started sim  

> select up

19 atoms, 18 bonds, 1 residue, 1 model selected  

> select #1

272143 atoms, 275532 bonds, 43 pseudobonds, 16666 residues, 29 models selected  

> select #1

272143 atoms, 275532 bonds, 43 pseudobonds, 16666 residues, 29 models selected  

> hide sel atoms

> hide sel cartoons

> select #1&ligand

6507 atoms, 6518 bonds, 46 residues, 1 model selected  

> show sel atoms

> select #1@H*

136505 atoms, 16660 residues, 1 model selected  

> hide sel atoms

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> select #1

272143 atoms, 275532 bonds, 43 pseudobonds, 16666 residues, 29 models selected  

> hide sel atoms

> hide sel cartoons

> select #1&ligand

6507 atoms, 6518 bonds, 46 residues, 1 model selected  

> show sel atoms

> select #1@H*

136505 atoms, 16660 residues, 1 model selected  

> hide sel atoms

> select clear

> volume #5 level 0.1845

> isolde add ligand CDL

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> ui mousemode right "translate selected atoms"

> isolde sim start #1.2/R:1000

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde add ligand CDL

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> ui mousemode right "translate selected atoms"

> isolde sim start #1.2/Es:1001

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde add ligand CDL

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> ui mousemode right "translate selected atoms"

> isolde sim start #1.2/E4:1004

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde add ligand CDL

place_ligand() was called with use_md_template=True, but no suitable template
was found. This command has been ignored.  

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> select #1&ligand

7531 atoms, 7538 bonds, 50 residues, 1 model selected  

> select up

256 atoms, 255 bonds, 1 residue, 1 model selected  

> isolde sim start #1.2/F9:1000

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> molmap #1 3.5

Opened superComplexConsolidatedV1.cif map 3.5 as #6, grid size 226,226,275,
pixel 1.17, shown at level 0.105, step 1, values float32  

> hide #!5 models

> select up

1430 atoms, 1455 bonds, 68 residues, 1 model selected  

> select up

273167 atoms, 276552 bonds, 16670 residues, 1 model selected  

> volume subtract #1 #4

Opened volume difference as #7, grid size 500,500,500, pixel 1.21, shown at
step 1, values float32  

> hide #!6 models

> volume #7 level 0.2094

> close #6

> close #7

> save /Users/rafaelrocha/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV6.cxs

Taking snapshot of stepper: superComplexConsolidatedV1.cif  

——— End of log from Thu Jan 16 15:16:15 2025 ———

opened ChimeraX session  

> show #!2 models

> hide #!2 models

> show #!4 models

> hide #!4 models

> show #!4 models

> hide #!4 models

> show #!4 models

> hide #!4 models

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp.mrc"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #6, grid size
500,500,500, pixel 1.21, shown at level 0.118, step 2, values float32  

> volume #6 step 1

> volume #6 level 0.1867

> select #1/L3

2477 atoms, 2500 bonds, 3 pseudobonds, 157 residues, 2 models selected  

> transparency #6.1 50

> alphafold fetch A0A640KEB4

Fetching AlphaFold database settings from
https://www.rbvi.ucsf.edu/chimerax/data/status/alphafold_database3.json  
Chain information for AlphaFold A0A640KEB4 #7  
---  
Chain | Description | UniProt  
A | Uncharacterized protein | A0A640KEB4_LEITA 1-328  
  
Color AlphaFold A0A640KEB4 by residue attribute pLDDT_score  

> hide #!6 models

> align #7:212-218@CA toAtoms #1/L3:212-218@CA

RMSD between 7 atom pairs is 0.684 angstroms  

> hide #7 models

> select clear

> align #7:212-259@CA toAtoms #1/L3:212-259@CA

RMSD between 48 atom pairs is 1.834 angstroms  

> show #7 models

> alphafold fetch A0A640KIH4

Chain information for AlphaFold A0A640KIH4 #8  
---  
Chain | Description | UniProt  
A | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | A0A640KIH4_LEITA 1-607  
  
Color AlphaFold A0A640KIH4 by residue attribute pLDDT_score  

> hide #8 models

> show #8 models

> hide #!6 models

> hide #7 models

> align #8:533-545@CA toAtoms #1/K5:533-545@CA

RMSD between 13 atom pairs is 0.416 angstroms  

> hide #!6 models

> show #7 models

> show #!6 models

> select #1/L3

2477 atoms, 2500 bonds, 3 pseudobonds, 157 residues, 2 models selected  

> save "/Users/rafaelrocha/supercomplex/supercomplexV2-IV2-II2-last
> model/chainL3.cif" models #1 selectedOnly true fixedWidth false

Not saving entity_poly_seq for non-authoritative sequences  

> save /Users/rafaelrocha/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/chainL3.cif
> models #1 selectedOnly true fixedWidth false

Not saving entity_poly_seq for non-authoritative sequences  

> select #1/K5

7523 atoms, 7592 bonds, 6 pseudobonds, 498 residues, 2 models selected  

> save /Users/rafaelrocha/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/chainK5.cif
> models #1 selectedOnly true

Not saving entity_poly_seq for non-authoritative sequences  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/chainK5.cif"

Summary of feedback from opening
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/chainK5.cif  
---  
warnings | Unknown polymer entity '46' on line 356  
Missing or incomplete sequence information. Inferred polymer connectivity.  
  
  
Chain information for chainK5.cif #9  
---  
Chain | Description  
K5 | No description available  
  

> select clear

> select #7:99-113

123 atoms, 124 bonds, 15 residues, 1 model selected  

> hide #!6 models

> select #7:312-325

115 atoms, 117 bonds, 14 residues, 1 model selected  

> select ~#1/L3&#1

270690 atoms, 274052 bonds, 40 pseudobonds, 16513 residues, 31 models selected  

> hide sel atoms

> hide sel cartoons

> hide #7 models

> hide #8 models

> hide #!9 models

> show #!9 models

> hide #!9 models

> show #!9 models

> hide #!9 models

> show #!9 models

> close #9

> show #8 models

> hide #8 models

> show #7 models

> show #!6 models

> hide #!6 models

> show #!6 models

> hide #!6 models

> select #7:312-325

115 atoms, 117 bonds, 14 residues, 1 model selected  

> delete #7:326-328

> delete #7:284-311

> show #!6 models

> hide #!6 models

> show #!6 models

> hide #!6 models

> delete #7:1-51

> delete #1/L3

> rename #7/A id L3

Invalid "id" argument: Expected an integer  

> rename #7/A ID L3

Expected a keyword  

> rename #7/A If L3

Expected a keyword  

> rename #7/A Id L31

Expected a keyword  

> changechains #7/A L3

Chain IDs of 246 residues changed  

> combine #1 #7

> select #1

270690 atoms, 274052 bonds, 40 pseudobonds, 16513 residues, 31 models selected  

> select #9

272683 atoms, 276088 bonds, 41 pseudobonds, 16759 residues, 3 models selected  

> hide sel cartoons

> select #9

272683 atoms, 276088 bonds, 41 pseudobonds, 16759 residues, 3 models selected  

> hide sel cartoons

> show sel atoms

> show sel cartoons

> hide sel atoms

> hide #!7 models

> show #!7 models

> hide #!7 models

> show #8 models

> hide #8 models

> hide #!9 models

> show #!7 models

> hide #!7 models

> show #!9 models

> close #1.2

Deleting atomic symmetry model...  
Deleting atomic symmetry model...  

> clipper associate #1 toModel #9

Deleting atomic symmetry model...  

> hide #!1 models

> hide #!1.1 models

> show #!1.1 models

> hide #!1.1 models

> hide #!1 models

> combine #9

> clipper associate #10 toModel #1

Invalid "toModel" argument: must specify 1 structure, got 0 for "#1"  

> select #10

272683 atoms, 276088 bonds, 41 pseudobonds, 16759 residues, 3 models selected  
No model chosen to save relative to  

> save /Users/rafaelrocha/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/combinationL3.cif
> models #10

Not saving entity_poly_seq for non-authoritative sequences  

> close #9

Deleting atomic symmetry model...  

> close #1

Deleting atomic symmetry model...  

> combine #6 to #10

Expected a keyword  

> clipper associate #6 toModel #10

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #1.1.1.1, grid size
500,500,500, pixel 1.21, shown at level 0.203, step 1, values float32  

> addh #1 hbond false

Summary of feedback from adding hydrogens to copy of combination #1.2  
---  
warning | Not adding hydrogens to copy of combination #1.2/GT ALA 93 CA because it is missing heavy-atom bond partners  
notes | No usable SEQRES records for copy of combination (#1.2) chain A; guessing termini instead  
No usable SEQRES records for copy of combination (#1.2) chain A0; guessing
termini instead  
No usable SEQRES records for copy of combination (#1.2) chain AG; guessing
termini instead  
No usable SEQRES records for copy of combination (#1.2) chain AU; guessing
termini instead  
No usable SEQRES records for copy of combination (#1.2) chain Ab; guessing
termini instead  
85 messages similar to the above omitted  
Termini for copy of combination (#1.2) chain L3 determined from SEQRES records  
Chain-initial residues that are actual N termini: copy of combination #1.2/A
ALA 34, copy of combination #1.2/A0 PRO 204, copy of combination #1.2/AG PHE
18, copy of combination #1.2/AU LYS 35, copy of combination #1.2/Ab GLU 206,
copy of combination #1.2/Aj LYS 208, copy of combination #1.2/Aq LYS 25, copy
of combination #1.2/Ar LEU 23, copy of combination #1.2/B ALA 23, copy of
combination #1.2/BI ALA 23, copy of combination #1.2/BK THR 37, copy of
combination #1.2/BP GLY 22, copy of combination #1.2/C SER 85, copy of
combination #1.2/C0 ILE 33, copy of combination #1.2/C1 ILE 33, copy of
combination #1.2/C2 ILE 33, copy of combination #1.2/C3 ILE 33, copy of
combination #1.2/C4 SER 34, copy of combination #1.2/C5 ILE 33, copy of
combination #1.2/C6 ILE 33, copy of combination #1.2/C7 ILE 33, copy of
combination #1.2/C8 ILE 33, copy of combination #1.2/C9 ILE 33, copy of
combination #1.2/D TYR 18, copy of combination #1.2/D6 VAL 7, copy of
combination #1.2/E PHE 33, copy of combination #1.2/E1 LEU 51, copy of
combination #1.2/E4 GLN 35, copy of combination #1.2/Ek ASN 26, copy of
combination #1.2/Eq ASN 62, copy of combination #1.2/Es VAL 2, copy of
combination #1.2/Ev GLY 3, copy of combination #1.2/F9 HIS 37, copy of
combination #1.2/FF HIS 98, copy of combination #1.2/FH VAL 18, copy of
combination #1.2/FL MET 1, copy of combination #1.2/FO PHE 12, copy of
combination #1.2/Fy PRO 60, copy of combination #1.2/Fz VAL 58, copy of
combination #1.2/GT ALA 6, copy of combination #1.2/I0 SER 160, copy of
combination #1.2/IE LYS 26, copy of combination #1.2/IY SER 2, copy of
combination #1.2/Il TYR 26, copy of combination #1.2/Ix ASP 152, copy of
combination #1.2/Iy THR 22, copy of combination #1.2/J6 THR 2, copy of
combination #1.2/JC GLU 22, copy of combination #1.2/JI PRO 11, copy of
combination #1.2/JJ MET 1, copy of combination #1.2/JN ALA 2, copy of
combination #1.2/Jw VAL 21, copy of combination #1.2/Jx LYS 11, copy of
combination #1.2/K5 ALA 14, copy of combination #1.2/KI THR 26, copy of
combination #1.2/Ke ALA 44, copy of combination #1.2/Kp PRO 53, copy of
combination #1.2/Ks GLU 4, copy of combination #1.2/LG TRP 20, copy of
combination #1.2/LO TYR 37, copy of combination #1.2/LR SER 78, copy of
combination #1.2/LY PRO 182, copy of combination #1.2/M PRO 2, copy of
combination #1.2/Mg ILE 36, copy of combination #1.2/Mq SER 34, copy of
combination #1.2/Mr THR 38, copy of combination #1.2/NF LYS 30, copy of
combination #1.2/NM TYR 82, copy of combination #1.2/Np MET 1, copy of
combination #1.2/R MET 1, copy of combination #1.2/TB MET 18, copy of
combination #1.2/Y MET 1, copy of combination #1.2/a TYR 3, copy of
combination #1.2/t0 THR 38, copy of combination #1.2/t1 THR 2, copy of
combination #1.2/t2 TYR 37, copy of combination #1.2/t3 PHE 18, copy of
combination #1.2/t4 LEU 23, copy of combination #1.2/t5 THR 26, copy of
combination #1.2/t6 MET 1, copy of combination #1.2/t7 MET 1, copy of
combination #1.2/t8 VAL 21, copy of combination #1.2/t9 ASP 152, copy of
combination #1.2/ta MET 1, copy of combination #1.2/tb SER 160, copy of
combination #1.2/tc THR 22, copy of combination #1.2/td TYR 26, copy of
combination #1.2/te GLU 4, copy of combination #1.2/tf ALA 2, copy of
combination #1.2/tg PRO 182, copy of combination #1.2/AG PHE 18, copy of
combination #1.2/Ar LEU 23, copy of combination #1.2/I0 SER 160, copy of
combination #1.2/Il TYR 26, copy of combination #1.2/Ix ASP 152, copy of
combination #1.2/Iy THR 22, copy of combination #1.2/J6 THR 2, copy of
combination #1.2/JI PRO 11, copy of combination #1.2/JI GLU 259, copy of
combination #1.2/JJ MET 1, copy of combination #1.2/JN ALA 2, copy of
combination #1.2/Jw VAL 21, copy of combination #1.2/Jx LYS 11, copy of
combination #1.2/K5 ALA 14, copy of combination #1.2/K5 LYS 143, copy of
combination #1.2/K5 ARG 299, copy of combination #1.2/K5 LYS 338, copy of
combination #1.2/K5 ILE 361, copy of combination #1.2/K5 GLU 490, copy of
combination #1.2/K5 MET 567, copy of combination #1.2/KI THR 26, copy of
combination #1.2/Ke ALA 44, copy of combination #1.2/Kp PRO 53, copy of
combination #1.2/Ks GLU 4, copy of combination #1.2/LG TRP 20, copy of
combination #1.2/LO TYR 37, copy of combination #1.2/LR SER 78, copy of
combination #1.2/LY PRO 182, copy of combination #1.2/M PRO 2, copy of
combination #1.2/Mg ILE 36, copy of combination #1.2/Mq SER 34, copy of
combination #1.2/Mr THR 38, copy of combination #1.2/NF LYS 30, copy of
combination #1.2/NF ARG 189, copy of combination #1.2/NM TYR 82, copy of
combination #1.2/Np MET 1, copy of combination #1.2/TB MET 18, copy of
combination #1.2/Y MET 1, copy of combination #1.2/t0 THR 38, copy of
combination #1.2/t1 THR 2, copy of combination #1.2/t2 TYR 37, copy of
combination #1.2/t3 PHE 18, copy of combination #1.2/t4 LEU 23, copy of
combination #1.2/t5 THR 26, copy of combination #1.2/t6 MET 1, copy of
combination #1.2/t7 MET 1, copy of combination #1.2/t8 VAL 21, copy of
combination #1.2/t9 ASP 152, copy of combination #1.2/ta MET 1, copy of
combination #1.2/tb SER 160, copy of combination #1.2/tc THR 22, copy of
combination #1.2/td TYR 26, copy of combination #1.2/te GLU 4, copy of
combination #1.2/tf ALA 2, copy of combination #1.2/tg PRO 182, copy of
combination #1.2/R MET 1, copy of combination #1.2/A ALA 34, copy of
combination #1.2/A0 PRO 204, copy of combination #1.2/AU LYS 35, copy of
combination #1.2/AU GLN 151, copy of combination #1.2/AU GLN 436, copy of
combination #1.2/Ab GLU 206, copy of combination #1.2/Ab THR 521, copy of
combination #1.2/Aj LYS 208, copy of combination #1.2/Aq LYS 25, copy of
combination #1.2/B ALA 23, copy of combination #1.2/BI ALA 23, copy of
combination #1.2/BK THR 37, copy of combination #1.2/BK GLN 151, copy of
combination #1.2/BK VAL 437, copy of combination #1.2/BP GLY 22, copy of
combination #1.2/C SER 85, copy of combination #1.2/C0 ILE 33, copy of
combination #1.2/C1 ILE 33, copy of combination #1.2/C2 ILE 33, copy of
combination #1.2/C3 ILE 33, copy of combination #1.2/C4 SER 34, copy of
combination #1.2/C5 ILE 33, copy of combination #1.2/C6 ILE 33, copy of
combination #1.2/C7 ILE 33, copy of combination #1.2/C8 ILE 33, copy of
combination #1.2/C9 ILE 33, copy of combination #1.2/D TYR 18, copy of
combination #1.2/D ILE 234, copy of combination #1.2/D6 VAL 7, copy of
combination #1.2/D6 VAL 63, copy of combination #1.2/E PHE 33, copy of
combination #1.2/E GLN 151, copy of combination #1.2/E GLN 438, copy of
combination #1.2/E1 LEU 51, copy of combination #1.2/E1 ASP 217, copy of
combination #1.2/E4 GLN 35, copy of combination #1.2/Ek ASN 26, copy of
combination #1.2/Eq ASN 62, copy of combination #1.2/Es VAL 2, copy of
combination #1.2/Ev GLY 3, copy of combination #1.2/F9 HIS 37, copy of
combination #1.2/FF HIS 98, copy of combination #1.2/FF MET 124, copy of
combination #1.2/FH VAL 18, copy of combination #1.2/FL MET 1, copy of
combination #1.2/FO PHE 12, copy of combination #1.2/Fy PRO 60, copy of
combination #1.2/Fz VAL 58, copy of combination #1.2/IE LYS 26, copy of
combination #1.2/IE VAL 199, copy of combination #1.2/IY SER 2, copy of
combination #1.2/JC GLU 22, copy of combination #1.2/a TYR 3, copy of
combination #1.2/GT ALA 6  
Chain-initial residues that are not actual N termini: copy of combination
#1.2/AU GLN 151, copy of combination #1.2/AU GLN 436, copy of combination
#1.2/Ab THR 521, copy of combination #1.2/BK GLN 151, copy of combination
#1.2/BK VAL 437, copy of combination #1.2/D ILE 234, copy of combination
#1.2/D6 VAL 63, copy of combination #1.2/E GLN 151, copy of combination #1.2/E
GLN 438, copy of combination #1.2/E1 ASP 217, copy of combination #1.2/FF MET
124, copy of combination #1.2/IE VAL 199, copy of combination #1.2/JI GLU 259,
copy of combination #1.2/K5 LYS 143, copy of combination #1.2/K5 ARG 299, copy
of combination #1.2/K5 LYS 338, copy of combination #1.2/K5 ILE 361, copy of
combination #1.2/K5 GLU 490, copy of combination #1.2/K5 MET 567, copy of
combination #1.2/NF ARG 189, copy of combination #1.2/L3 VAL 52, copy of
combination #1.2/L3 VAL 312  
Chain-final residues that are actual C termini: copy of combination #1.2/A PRO
357, copy of combination #1.2/A0 LYS 685, copy of combination #1.2/AU VAL 574,
copy of combination #1.2/Ab ARG 690, copy of combination #1.2/Aj HIS 690, copy
of combination #1.2/Aq GLN 187, copy of combination #1.2/B LYS 160, copy of
combination #1.2/BI GLN 187, copy of combination #1.2/BK VAL 574, copy of
combination #1.2/BP GLN 187, copy of combination #1.2/C MET 349, copy of
combination #1.2/C0 SER 106, copy of combination #1.2/C1 SER 106, copy of
combination #1.2/C2 SER 106, copy of combination #1.2/C3 SER 106, copy of
combination #1.2/C4 SER 106, copy of combination #1.2/C5 SER 106, copy of
combination #1.2/C6 SER 106, copy of combination #1.2/C7 SER 106, copy of
combination #1.2/C8 SER 106, copy of combination #1.2/C9 SER 106, copy of
combination #1.2/D VAL 258, copy of combination #1.2/D6 THR 70, copy of
combination #1.2/E GLY 575, copy of combination #1.2/E1 GLY 239, copy of
combination #1.2/E4 GLY 203, copy of combination #1.2/Ek SER 103, copy of
combination #1.2/Eq TYR 145, copy of combination #1.2/Es HIS 136, copy of
combination #1.2/Ev ALA 386, copy of combination #1.2/F9 GLN 103, copy of
combination #1.2/FF PRO 174, copy of combination #1.2/FH VAL 157, copy of
combination #1.2/FL GLY 233, copy of combination #1.2/FO ALA 159, copy of
combination #1.2/Fy ALA 117, copy of combination #1.2/Fz VAL 105, copy of
combination #1.2/IE GLY 204, copy of combination #1.2/IY ASN 295, copy of
combination #1.2/JC GLU 183, copy of combination #1.2/R HIS 62, copy of
combination #1.2/a GLN 96, copy of combination #1.2/AG SER 196, copy of
combination #1.2/Ar TRP 118, copy of combination #1.2/I0 LYS 383, copy of
combination #1.2/Il GLU 104, copy of combination #1.2/Ix ILE 279, copy of
combination #1.2/Iy GLN 115, copy of combination #1.2/J6 PHE 199, copy of
combination #1.2/JI PHE 252, copy of combination #1.2/JI LYS 491, copy of
combination #1.2/JJ ILE 549, copy of combination #1.2/JN VAL 108, copy of
combination #1.2/Jw PHE 144, copy of combination #1.2/Jx ASP 124, copy of
combination #1.2/K5 ILE 138, copy of combination #1.2/K5 GLU 268, copy of
combination #1.2/K5 LEU 311, copy of combination #1.2/K5 VAL 354, copy of
combination #1.2/K5 ALA 484, copy of combination #1.2/K5 ARG 546, copy of
combination #1.2/K5 PRO 602, copy of combination #1.2/KI GLU 225, copy of
combination #1.2/Ke LEU 138, copy of combination #1.2/Kp GLU 224, copy of
combination #1.2/Ks ALA 156, copy of combination #1.2/LG SER 123, copy of
combination #1.2/LO LYS 342, copy of combination #1.2/LR GLY 148, copy of
combination #1.2/LY ALA 345, copy of combination #1.2/M PHE 103, copy of
combination #1.2/Mg ALA 250, copy of combination #1.2/Mq LYS 90, copy of
combination #1.2/Mr LEU 147, copy of combination #1.2/NF LEU 183, copy of
combination #1.2/NF SER 246, copy of combination #1.2/NM MET 144, copy of
combination #1.2/Np VAL 283, copy of combination #1.2/TB THR 81, copy of
combination #1.2/Y ILE 210, copy of combination #1.2/t0 LEU 147, copy of
combination #1.2/t1 PHE 199, copy of combination #1.2/t2 LYS 342, copy of
combination #1.2/t3 SER 196, copy of combination #1.2/t4 TRP 118, copy of
combination #1.2/t5 GLU 225, copy of combination #1.2/t6 ILE 549, copy of
combination #1.2/t7 VAL 283, copy of combination #1.2/t8 PHE 144, copy of
combination #1.2/t9 ILE 279, copy of combination #1.2/ta ILE 210, copy of
combination #1.2/tb LYS 383, copy of combination #1.2/tc GLN 115, copy of
combination #1.2/td GLU 104, copy of combination #1.2/te ALA 156, copy of
combination #1.2/tf VAL 108, copy of combination #1.2/tg ALA 345, copy of
combination #1.2/R HIS 62, copy of combination #1.2/A PRO 357, copy of
combination #1.2/A0 LYS 685, copy of combination #1.2/AU LEU 139, copy of
combination #1.2/AU ASP 430, copy of combination #1.2/AU VAL 574, copy of
combination #1.2/Ab VAL 515, copy of combination #1.2/Ab ARG 690, copy of
combination #1.2/Aj HIS 690, copy of combination #1.2/Aq GLN 187, copy of
combination #1.2/B LYS 160, copy of combination #1.2/BI GLN 187, copy of
combination #1.2/BK GLY 138, copy of combination #1.2/BK ASP 430, copy of
combination #1.2/BK VAL 574, copy of combination #1.2/BP GLN 187, copy of
combination #1.2/C MET 349, copy of combination #1.2/C0 SER 106, copy of
combination #1.2/C1 SER 106, copy of combination #1.2/C2 SER 106, copy of
combination #1.2/C3 SER 106, copy of combination #1.2/C4 SER 106, copy of
combination #1.2/C5 SER 106, copy of combination #1.2/C6 SER 106, copy of
combination #1.2/C7 SER 106, copy of combination #1.2/C8 SER 106, copy of
combination #1.2/C9 SER 106, copy of combination #1.2/D LYS 206, copy of
combination #1.2/D VAL 258, copy of combination #1.2/D6 LEU 52, copy of
combination #1.2/D6 THR 70, copy of combination #1.2/E LEU 139, copy of
combination #1.2/E ALA 429, copy of combination #1.2/E GLY 575, copy of
combination #1.2/E1 GLU 123, copy of combination #1.2/E1 GLY 239, copy of
combination #1.2/E4 GLY 203, copy of combination #1.2/Ek SER 103, copy of
combination #1.2/Eq TYR 145, copy of combination #1.2/Es HIS 136, copy of
combination #1.2/Ev ALA 386, copy of combination #1.2/F9 GLN 103, copy of
combination #1.2/FF TYR 118, copy of combination #1.2/FF PRO 174, copy of
combination #1.2/FH VAL 157, copy of combination #1.2/FL GLY 233, copy of
combination #1.2/FO ALA 159, copy of combination #1.2/Fy ALA 117, copy of
combination #1.2/Fz VAL 105, copy of combination #1.2/IE VAL 194, copy of
combination #1.2/IE GLY 204, copy of combination #1.2/IY ASN 295, copy of
combination #1.2/JC GLU 183, copy of combination #1.2/a GLN 96, copy of
combination #1.2/GT ALA 93  
Chain-final residues that are not actual C termini: copy of combination
#1.2/AG SER 196, copy of combination #1.2/AU LEU 139, copy of combination
#1.2/AU ASP 430, copy of combination #1.2/Ab VAL 515, copy of combination
#1.2/Ar TRP 118, copy of combination #1.2/BK GLY 138, copy of combination
#1.2/BK ASP 430, copy of combination #1.2/D LYS 206, copy of combination
#1.2/D6 LEU 52, copy of combination #1.2/E LEU 139, copy of combination #1.2/E
ALA 429, copy of combination #1.2/E1 GLU 123, copy of combination #1.2/FF TYR
118, copy of combination #1.2/GT ALA 93, copy of combination #1.2/I0 LYS 383,
copy of combination #1.2/IE VAL 194, copy of combination #1.2/Il GLU 104, copy
of combination #1.2/Ix ILE 279, copy of combination #1.2/Iy GLN 115, copy of
combination #1.2/J6 PHE 199, copy of combination #1.2/JI LYS 491, copy of
combination #1.2/JI PHE 252, copy of combination #1.2/JJ ILE 549, copy of
combination #1.2/JN VAL 108, copy of combination #1.2/Jw PHE 144, copy of
combination #1.2/Jx ASP 124, copy of combination #1.2/K5 PRO 602, copy of
combination #1.2/K5 ILE 138, copy of combination #1.2/K5 GLU 268, copy of
combination #1.2/K5 LEU 311, copy of combination #1.2/K5 VAL 354, copy of
combination #1.2/K5 ALA 484, copy of combination #1.2/K5 ARG 546, copy of
combination #1.2/KI GLU 225, copy of combination #1.2/Ke LEU 138, copy of
combination #1.2/Kp GLU 224, copy of combination #1.2/Ks ALA 156, copy of
combination #1.2/LG SER 123, copy of combination #1.2/LO LYS 342, copy of
combination #1.2/LR GLY 148, copy of combination #1.2/LY ALA 345, copy of
combination #1.2/M PHE 103, copy of combination #1.2/Mg ALA 250, copy of
combination #1.2/Mq LYS 90, copy of combination #1.2/Mr LEU 147, copy of
combination #1.2/NF SER 246, copy of combination #1.2/NF LEU 183, copy of
combination #1.2/NM MET 144, copy of combination #1.2/Np VAL 283, copy of
combination #1.2/TB THR 81, copy of combination #1.2/Y ILE 210, copy of
combination #1.2/t0 LEU 147, copy of combination #1.2/t1 PHE 199, copy of
combination #1.2/t2 LYS 342, copy of combination #1.2/t3 SER 196, copy of
combination #1.2/t4 TRP 118, copy of combination #1.2/t5 GLU 225, copy of
combination #1.2/t6 ILE 549, copy of combination #1.2/t7 VAL 283, copy of
combination #1.2/t8 PHE 144, copy of combination #1.2/t9 ILE 279, copy of
combination #1.2/ta ILE 210, copy of combination #1.2/tb LYS 383, copy of
combination #1.2/tc GLN 115, copy of combination #1.2/td GLU 104, copy of
combination #1.2/te ALA 156, copy of combination #1.2/tf VAL 108, copy of
combination #1.2/tg ALA 345, copy of combination #1.2/L3 HIS 283, copy of
combination #1.2/L3 ARG 325  
Missing OXT added to C-terminal residue copy of combination #1.2/AG SER 196  
Missing OXT added to C-terminal residue copy of combination #1.2/Ar TRP 118  
Missing OXT added to C-terminal residue copy of combination #1.2/I0 LYS 383  
Missing OXT added to C-terminal residue copy of combination #1.2/Il GLU 104  
Missing OXT added to C-terminal residue copy of combination #1.2/Ix ILE 279  
51 messages similar to the above omitted  
Adding 'H' to copy of combination #1.2/L3 VAL 52  
Adding 'H' to copy of combination #1.2/L3 VAL 312  
copy of combination #1.2/L3 ARG 325 is not terminus, removing H atom from 'C'  
1999 hydrogens added  
  

> select ~#1/L3&#1

270747 atoms, 274109 bonds, 40 pseudobonds, 16513 residues, 9 models selected  

> hide sel atoms

> hide sel cartoons

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/chainL3.cif"

Summary of feedback from opening
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/chainL3.cif  
---  
warnings | Unknown polymer entity '51' on line 354  
Missing or incomplete sequence information. Inferred polymer connectivity.  
  
  
Chain information for chainL3.cif #6  
---  
Chain | Description  
L3 | No description available  
  

> volume #1.1.1.1 style surface

> transparency sel 50

ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 44 residues in model #1.2 to IUPAC-IUB
standards.  

> matchmaker #6 to #1.2

Computing secondary structure  
Parameters  
---  
Chain pairing | bb  
Alignment algorithm | Needleman-Wunsch  
Similarity matrix | BLOSUM-62  
SS fraction | 0.3  
Gap open (HH/SS/other) | 18/18/6  
Gap extend | 1  
SS matrix |  |  | H | S | O  
---|---|---|---  
H | 6 | -9 | -6  
S |  | 6 | -6  
O |  |  | 4  
Iteration cutoff | 2  
  
Matchmaker copy of combination, chain L3 (#1.2) with chainL3.cif, chain L3
(#6), sequence alignment score = 562.7  
RMSD between 77 pruned atom pairs is 1.065 angstroms; (across all 157 pairs:
26.079)  
  

> color #6 bychain

> color #6 byhetero

> color modify #6 hue + 50

Computing secondary structure  
s1:
ASKEEQIKKNTKIAIEMIRRYKGETPMSYTRKHTATIEQLEREIEALLGGAQKMRKATTDDQPMDKLGLMERCLRHALWSYHKDEGKYDFDEIARWVVYTPEDEVKLAQMKRQVEAKSKLAAYRAKRAEQGLPEAPVPQISWEEEYKNVTDRELVNEKRLRYDTIAANTMERDEAQIEAVLQQYRKPIQDKRLDDLVDLLERFKPVLAREAIMQRLTIKHLEGQLGVWRYMDWCPEVRDRAELEVDISGFQWWSPLEERRLLPVRLRSVNEVREIMAQTQSSKAAEASAHSPQASQSAGDGDRERLLKEVLALQARIHQRDDAP  
s2:
.............................VNKVPASL..LEKVCNPRLVAFTAMDLARTRFAP.....LYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVL..IRSPDTHPNLQR.................................................................................................................................  
s1:
PAEHKGRVGYVSQVIGAVVDVHFSEGVPPVLTALDVTEDLGRDEPLTLEIVQHLDANTGRCIAMQTTDLLKLKSKVVSTGGNISVPVGRETLGRIFNVLGDAIDQRGPVGEKMRMAIHAEAPKLADQAAEDTILTTGIKVIDLILPYCKGGKIGLFGGAGVGKTVIIMELINNVAKGHGGFSVFAGVGERTREGTDLYLEMMQSKVIDLKGDSKCVLVYGQMNEPPGARARVAQSALTMAEYFRDVEGQNVLLFIDNIFRFTQANSEVSALLGRIPAAVGYQPTLAEDLGMLQERITSTTKGSITSVQAVYVPADDITDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMDPDVIDVNHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQVAEVFTGMTGHYVQLNDTVESFSGLLMGSYDQIPEMAFYMVGGINSVLEKAKAMAEEAAAMEK  
s2:
....................................................................................................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQP..TP...GVRTAVKDAFDT...SVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........................  
s1:
FFGKGWDNAALDTIFSSMLRKPEVNDRIRTQYASTMDPRDADVLRRLGEVSKENKTFIRVFLPPHLGDPHRLLKCYSLMAYPILDDKGGQLKVEMDGCKLDAFADPDDDYSKVVIPHIELVEYLAKSLLETMKWEATPRGAASLLESLYRGAEIPDHVFQTPAVIERLEDYKDGNKVIS.......................................................................................................  
s2:
........................................................................................................................VNKVPASLLEKV...CNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFS..KDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
KATEMIGYVHSIDGTIATLIPAPGNPGVAYNTIIMIQVSPTTFAAGLVFNLEKDGRIGIILMDNITEVQSGQKVMATGKLLYIPVGAGVLGKVVNPLGHEVPVGLQTLGKVDAGAPNIVSRSPVNYNLLTGFKAVDTMIPIGRGQRELIVGDRQTGKTSIAVSTIINQVRNNQQI......LSKNAVISIYVSIGQR.CSNVARIHRLLRSYGALRYTTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNVAMKAVAGKLKGILAEYRKLAADQVQTVPMIRGARFVALFNQKNPSFFMNALVSLYACLNGYLDDVKVNYAKLYEYLLVNKDLSVMYGTATNKFFYMYVQQLNYVIRFFTLNHPILNAEVEEMLKQHTHLFLQHYQSKMNAIKTEKEIKALKNLLYSCKRAV  
s2:
.............................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVR.TAVKDA..FDTSVCNDIANILRIG.GETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIE.....YPERGEVHV.LIRSPDTHPNLQR...............................................................................................................................................................................................................  
s1:
EHKGRVGYVSQVIGAVVDVHFSEGVPPVLTALDVTEDLGRDEPLTLEIVQHLDANTGRCIAMQTTDLLKLKSKVVSTGGNISVPVGRETLGRIFNVLGDAIDQRGPVGEKMRMAIHAEAPKLADQAAEDTILTTGIKVIDLILPYCKGGKIGLFGGAGVGKTVIIMELINNVAKGHGGFSVFAGVGERTREGTDLYLEMMQSKVIDLKGDSKCVLVYGQMNEPPGARARVAQSALTMAEYFRDVEGQN...VLLFIDN..IFRFTQANSEVSALLG.RIPAAVGYQPTLAEDLGMLQERITSTTKGSITSVQAVYVTDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMDPDVIDVNHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQVAEVFTGMTGHYVQLNDTVESFSGLLMGSYDQIPEMAFYMVGGINSVLEKAKAMAEEAAAMEKQRRAR  
s2:
...........................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANIL.RIGGET.HAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFND.GPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR...........................................................................................................  
s1:
KGRVGYVSQVIGAVVDVHFSEGVPPVLTALDVTEDLGRDEPLTLEIVQHLDANTGRCIAMQTTDLLKLKSKVVSTGGNISVPVGRETLGRIFNVLGDAIDQRGPVGEKMRMAIHAEAPKLADQAAEDTILTTGIKVIDLILPYCKGGKIGLFGGAGVGKTVIIMELINNVAKGHGGFSVFAGVGERTREGTDLYLEMMQSKVIDLKGDSKCVLVYGQMNEPPGARARVAQSALTMAEYFRDVEGQNVLLFIDNIFRFTQANSEVSALLGRIPAAVGYQPTLAEDLGMLQERITSTTKGSITSVQAVYVPADDITDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMDPDVIDVNHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQVAEVFTGMTGHYVQLNDTVESFSGLLMGSYDQIPEMAFYMVGGINSVLEKAKAMAEEAAAMEENKAAH  
s2:
................................................................................................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQP..TP...GVRTAVKDAFDT...SVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR..............................  
s1:
.............................................................KYDLFGYEV..DTNTAPWIEKVKKCRYYDEAGEVLVSMNVKNCPPDLETYNATLQKIFEAPSKQEKPVENESKFCAMMDLMEEMQHRNKVK.....PNEESWTWVMKECVQSGQFRLGYCVAKLMEAEFKRVPEDLVKQNEANAAKAKADGKEHPSTLAQQQSLFDIKIQ  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVP.....YSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.....................................................................  
s1:
.....................................................................................LHFPLSPPPIEIDY.LDSDPLEFAVRTEARRWGFDDLQYMRELAFVRIKENPSIGDFRRM..TPEERRDLFWGSDRQDFFRYITLKLTGHPEHLYHRGW  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR...........................  
s1:
ASDLKMVSLHKILIGEVQFRNNALLKACNIEHNFGPTWKSEIEAYAKSLPAEEKNCLERQIARVSMTRYTTRELAEYCGEGPEHVDAVAREANIAQAKVYAQKNGADKLETYVKAEAKNA....GWSEAETK....KFMDAVKAAK......................................................  
s2:
.........................................VNKVPASL..LEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
...........................................................AKKYDLFGYEVDTNTAP..WIEKVKKCRYYDEAGEVLVSMNVKNCPPDLETYNATLQKIFEAPSKQEKPVENESKFCAMMDLMEEMQHRNKVK.....PNEESWTWVMKECVQSGQFRLGYCVAKLMEAEFKRVPEDLVKQNEANAAKAKADGKEHPSTLAQQQSLFDIKIQ  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVP.....YSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.....................................................................  
s1:
TEMIGYVHSIDGTIATLIPAPGNPGVAYNTIIMIQVSPTTFAAGLVFNLEKDGRIGIILMDNITEVQSGQKVMATGKLLYIPVGAGVLGKVVNPLGHEVPVGQTLGKVDAGAPNIVSRSPVNYNLLTGFKAVDTMIPIGRGQRELIVGDRQTGKTSIAVSTIINQVRNNQQI......LSKNAVISIYVSIGQR.CSNVARIHRLLRSYGALRYTTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNVAMKAVAGKLKGILAEYRKLAADVQTVPMIRGARFVALFNQKNPSFFMNALVSLYACLNGYLDDVKVNYAKLYEYLLVNKDLSVMYGTATNKFFYMYVQQLNYVIRFFTLNHPILNAEVEEMLKQHTHLFLQHYQSKMNAIKTEKEIKALKNLLYSCKRAV  
s2:
..........................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVR.TAVKDA..FDTSVCNDIANILRIG.GETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIE.....YPERGEVHV.LIRSPDTHPNLQR..............................................................................................................................................................................................................  
s1:
........................................................GAKK..YDLFGYEV..DTNTAPWIEKVKKCRYYDEAGEVLVSMNVKNCPPDLETYNATLQKIFEAPSKQEKPVENESKFCAMMDLMEEMQHRNKVK.....PNEESWTWVMKECVQSGQFRLGYCVAKLMEAEFKRVPEDLVKQNEANAAKAKADGKEHPSTLAQQQSLFDIKIQ  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVP.....YSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.....................................................................  
s1:
SIAVIAAGAPAALLQAVSSILSKATGGAVKATQATSAA.SNAVVVGMQAPRGVYACVAEPPSTASGPYAGVKTVVVRAILPRSAPDTMQVRDILDVYPASGIACEKETAEAVKNFTKAAKVAVEKAKAMKATRVTLVMKPATKYERLNGLFRETCTKTIEAAGLSVETSTTAAATNTLIMFPEK..MSVVMVSDDPVCENVQYAYAGAVGGVHTTYYTDSGNKIYGGHSYRSVAMALAEELKSLGMKAEAAKVEAAVQKSPRNAAAAM  
s2:
............VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQ.PTPGVRTAVKDAF......DTSVCNDIANILRIGG.....ET......HAHAHRMALKILDDMNLMRVP...............YSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPD.THPNLQR.................................................................  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
..................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
SIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
..................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
..................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
..................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..........YTPSEELKKLYASDFERAQFP...ANIVPSDSVTFAKFLYKAVEPKGSFDAILKDFQTIAAAIPK..LPIFWERTV........VVSEVNEFK.SLSAPTIFTLEWMQSN.GMLDLLPDVAEVYETYVSAKMKRVTAKIYVAPGKEQDRALVDKARKVAEQVVKDNKQLAGYTLVPKVLVDRSIVEGFAVDVQGTYVNEAVGRKIETEVLRKYLDSLSLYDAEELKSGV  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR..................................................................................  
s1:
VALNWRDHGISYVKYLNVATEALHMATKDKARAKYSRFSTPNYIALVKKVPAFT.....................................................................................................................................................  
s2:
..............................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
FFKATEMIGYVHSIDGTIATLIPAPGNPGVAYNTIIMIQVSPTTFAAGLVFNLEKDGRIGIILMDNITEVQSGQKVMATGKLLYIPVGAGVLGKVVNPLGHEVPVGLQTLGKVDAGAPNIVSRSPVNYNLLTGFKAVDTMIPIGRGQRELIVGDRQTGKTSIAVSTIINQVRNNQQI......LSKNAVISIYVSIGQR.CSNVARIHRLLRSYGALRYTTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNVAMKAVAGKLKGILAEYRKLAAQTVPMIRGARFVALFNQKNPSFFMNALVSLYACLNGYLDDVKVNYAKLYEYLLVNKDLSVMYGTATNKFFYMYVQQLNYVIRFFTLNHPILNAEVEEMLKQHTHLFLQHYQSKMNAIKTEKEIKALKNLLYSCKRAVG  
s2:
...............................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVR.TAVKDA..FDTSVCNDIANILRIG.GETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIE.....YPERGEVHV.LIRSPDTHPNLQR.............................................................................................................................................................................................................  
s1:
LSLLLCVHFSAIHR..PPPPVPFTALA......AFLYALTLTAPVAEQRS..GSSLHPQIEVGTEIEDMALFHLVVLPLVFFAAMCIGRG.........................................................................  
s2:
...VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYT.SIEQQVAKRFSKDPSKLQPTPGVRTAVKD..AFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
QMKVELTMQYLDEWMLRWRKFQTESDWQIEKNRQWWRKANIVTAGAVMGGLVMYTAGNATIRRQFGAPHFFDIGVDGKLKEAICDTMTSRWRYTPQGYGRVMLVGLPTFFVFAISEHIQERRRLRAYVRQNTVFGEQARRLVQNGKIEEYLAVDIKASLP.QNQTQLYAG....................................................................  
s2:
.......................................................................VNKVPASLLEKVCN..PRLVAFTAMDLARTRFAPLYT....SIEQQVAKRFSKDPSKLQPT...PGVRTAVKDA.FDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
.............................................................................................................................................NMFLFKDPVRRPQLSPEERAKVKINYAEWPEEFRDYDPDDPYKNSPEIIEGLSSWNLFLWGVECAFIYQFYEVVFPKS  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR..............................................................  
s1:
....................NPVDHFRPNLKFLSVYVEHQYVVDKWLHVKENWLKPWYLPWW.TPMYQAM.TWYSQRNRNLMLVENHLNYRPYRYRRNDEDREN....PY...................................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLAR..TRFAPLYTSIEQQVAKRFSKDPSKLQP..TPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
VFFSTYRSKRIVAPGFLKGPVMASRAFFDYYFQRAWCGCVQWVIPGEVRLWACGVPVIYFIHRYHNDHSLEPDFVEKAMIQRWGG..SLEEVR.KLSPQDQLRIRAFTDLEKLYSAYGPKD.TIVQP.PGDLLPGKDYYH..........................................................................................  
s2:
..................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAP.......LYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
GTWSVLKKNCLNFVPGLALFASQSRDAFATWMKIYNRGYKYGPQEFSDQAEAYTPDYWKRGHSQEKNMWVDMKLSEEVSQKELAQLMHYKQDLWRMGHGLGLSLFLGGYALIPAFFCLSSDTFAPSCFCKTEEEKKAWREAQDMYRYRSAPSYIMDTKWHFD.FHAYPWN....ATQERAWDDLFEKNNVRRDPKVLRPAAEMYDGFLKFYQIRRKSLRHLARSMNLPTFPLLSRTCASTRVKDYWNLAWNEDYMVITQKLHHQMSDEDLHDYAWRRFLAPYDKNLSRDEIMTRVNDYHEFLGPKFVEEGKAPNMIILTNYVLGYYNDPAYLVEDISALDGNDFEYMAHYGKDAFLRRLEFENGPLRDQVEAHTQKLIADRAAAAAAEA  
s2:
.......................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.................................................................................................................  
s1:
HLEPMSVWYLSSWTCVWWYSFFFWLPVLWADMIVPSFVYNKLPVIHFIQEKRAEQKLRRVLDETYTQ................................................................................................................................  
s2:
......................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
...............................................HPPKLEDIP.PSSATKGFFGAYMARLIDIKWMMNRSVELGREYYISAPTLYLFLWMFCWKGFVIMRYGDGKPP.............................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCN..DIANIL....RIGGE..THAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
................................................................................................................VGNGPTFHTAGDNNNTSEIQNAFPINERG...IRSSSPFPEPNTAIYDSYMPWTYFQPIDVKVDKMPAPEAKYYQHHTKKPWDVSTTDLIEIQSRKKYVQGVGYFLMMIYLYFLMPKEKSYSGTTGSDGFYVMLPKNQPEKFV  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFND.GPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.................................................................................................  
s1:
MFVFFVCDLVIMRILLCFCYSVWSRIIFVLFYNVFYICTELMFCIFDVYLFVGLCMFICLWFVLFNFYGLIVYYCITYLNVYILFCIVFMYYMAFLFCFCFLLDFILFGSLLVGDAFMDVFFLRYLLCVLECFSLLCRCISTFLRMFCNLLSSHFLMLMFCDFVYFFIIFFLFFIMCDFIYFIIFTFAMLFCIIFYLFLYALDMFCALLQIFIFCNMIMQLIMDFLL...LLSFHG.......................................................................................................................................  
s2:
......................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
FTVPVALCTKQVAAMDEPLKRHIDAYEARGEDVTIAVWREYVDGQRALLPYRWAKFRNEVTYLTSGQIALTDLAFADLLLFVRFLTKCLFIFIVAVMAGRRSVFPS.LEPTSPFVEEIVKN.WQPNRLRRVAGAEYMARDQAAAAAAAAA................................................................  
s2:
........................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPT.PGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
........................................................................................................PKTLNQFRNFSYIVVAWLGFNKGFREKAANDAEWIAHQQRVRQQNVERHQAASAMMEA  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVP.....YSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..........................................................................................VAPKTLN.......QFRNFSYIVVAWLGFNKGFREKAANDAEWIAHQQRVRQQNV............  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
AFHDVSTDAIRQMQASEALQKHLENAQLAHRVCVAKALKADEPPVEK.CALTWGEVVMRYNQWSEYRPAFHDSDAQ..KRYSKYWTKKRQA......................................................................................................  
s2:
....................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
SRVSNKISGGMACQTVVNHGYYLKPMTGNPYLCTQHDGVTTAYQQGFAPKDFNWLYRFRYNLLPQGMSGGFFSRNPYGRYVHWLEVSTIEKMRLQMFTMESVPCSVVSLILLVFTMWHSYRLAFLHPDITLYNLG.LWSTKPWVQQQRFNKKKELDQDVYRWMTRVPEVMMDDPIREMYKM.GITANDPVYAMAKEQGVEHELTMTHAEYTSTSPDIRRVIANARK...................................  
s2:
..................................................................................................VNKVPASLLEKVC......NPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..................KLYASDFERAQFPANIVPSDSVTFAKFLYKA...VEP........KGSFD.AILKDFQTIAAAIPKLPIFWERTV..VVSEVNEFK.SLSAPTIFTLEWMQSN.GMLDLLPDVAEVYETYVSAKMKRVTAKIYVAPGKEQDRALVDKARKVAEQVVKDNKQLAGYTLVPKVLVDRSIVEGFAVDVVNEAVG  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRF.APLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR...................................................  
s1:
SGRLRLYKEKLEGYNRFYSIVKTIKMVTMAKFRQAQVRIKTRDYTL..RYTEKAFSKPGQLVGDSPQAKAIYIPVMTNRGSCGALNSNVVKVIDSVASSRAYLMPLGKRGIESLSKLYPSSFRMGIVNDM.HEPMHFAYATYVWENAQQLCPEADRVHIIFHRCVSAGSQKQCYYNIPAYEKWKEDLVDASSTENQKSRYLFANTLLNEDEQMIRDFYDFHATLAILNAVCENELSEQAARLVAVEGQLSNISTLQQKTSSLYNKTRQSSITSSLIEIISAMTSLEGNAAKGVQRTN  
s2:
.......VNKVPA..SLLEKVCNPRLVAFTAMDLARTRFAPL.YTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAF.DTSVCN.DIANILR.IGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEY..PERGEVHVLIRSPDTHPNLQR.............................................................................................................................  
s1:
.....YTELSHMKFP..VYYGAVGVVLGYFVVMWVVFLRMGSKHTARSEFKNDYLRVWRRRLGTGYEWADAWGPEMGTFFKDLPEE.........................................................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVC..NDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..........................................................DMHSSDRFKAA.WDEIP..LHMLGASHKQMFEWYWRAMYQLGL.RDPYRLT...KLRSMLNWAALFSFMYLTYISIFYSSFYHVYMM....DWPEHFKRENAREYALSHGHDVWAGDGKFIRPYFHINPPMLTMTSEDI  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR........................................  
s1:
..........................................................................TYFYANCGETGISGATMQVLLKLTLACCVVQVFAIRYFVFQRLTTKKQFVEDSTDLWESDGTEMDGEEAVANLRIQHERIMPFMNDIKDKLDAQ  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGE...VHVLIRSPDTHPNLQR........  
s1:
.................................................................................................TMNFGNMTLGGA....MATFGGQSNPMCNYTSPLAKKFV.YKEVGKVHYPLRRHVFRTKVRTAAEIRFNEIVKRYMKEKMTFKRGCYAATITNTVELDHMGSIIPKDEYEVKRLTSYMTSKKMSSDYKKHMQELWTRVLFVCESTNLVGVTENAMHQNSRPGTDEEFMSIIWYSSFVTTLMAFVVTLFIWWYRYGQAPQYAEF  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDN..SPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.............................................................................................................................................  
s1:
............................ELPEAFEFIEHKVTDKDIHSAYENMETLRLTVTRQDEFLFKETPVKCVTIVGVNGENGVYPGHAYEI.TQLTPAPLTVEMP.DGTVKKFFTSGGFAHINNEGSCDINCVECIPLAELDLDAAEKALAQQQSALSSAHDEKAKAVIEIRIGVLESVIQSLKHMKE  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAF...DTSV.CNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAF....NDGPFD.N....SPLLFEMIEYPERGEVHVLIRSPDTHPNLQR......................  
s1:
PLATLKPVLAESVATQNVIRRMIGVTTNRKVNASAINSVAEKTKGEGLAGTTAVVARAHLYLLSRNPTDAVAEIDAVLPKVQDEALRRFAIGIRLRSHNELLDMKEASLGVSGGATESEVSDLRSKLQKDYKELVTSSPGCWLVELAAAEYTLYTGASEEAYKSFSSIEKKIQEYIKAPIHVSELVATADNTNEFSLIGFQVRRARPGVKPEGVSASVAEGMANVMADPAAVKALQQAKKAFEEALELVVTLQEANV....GH...HFHDFFPTTPDHYDKWTSEAARSAQQLIQE.ALTPHSVGLKPEAIDRIRVSMTNKAFYDSEEKLHALLKSAPKDKSIIASIRETFGPGPSTPISSSDQAVADAVESVHLAVVSSDTAGATDYAKRGKEIAKALAKQLLYRTQVQKCVALTEMNCLQEAVDVVTPVIDANEYIYMWRAFLARSRAYKGLGLITNADKDLKELNRLKHSLTERTPYEKK  
s2:
..............................................................................................................................................................................VNKVPASLLEKVC...NPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSK...DPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIE........YPERGEVHVLIRSPDTHPNLQR..........................................................................................................................................  
s1:
MFWLCLVCLSVSHKMIGLCYLLVAILSGFVGYVYSLFIRLELSLIGCGILFGDYQFYNVLITSHGLIMVFAFIMPVMMGGLVNYFIPVMAGFPDMVFPRLNNMSFWMYLAGFGCVVNGFLTEEGMGVGWTLYPTLICIDFHSSLACDFVMFAVHLLGISSILNSINLLGTLFCCRRKFFSFLSWSLFIWAALITAILLIITLPVLAGGVTLILCDRNFNTSFYDVVG.....GGDLILFQHIFWFFGHPEVYIILLPVFGLISTIVEVIGFR.CVFSTVAMIYSMILIAILGMFVWAHHMFVVGMDVDSRAYFGGVSILIGLPTCVKLFNWIYSFLYTDMIITFEVYFVIMFIFMFLIGAVTGLFLSNVGIDIMLHDTYFVVGHFHYVLSLGAVVGFFTGFIHFLAKWLPIELYLFWMFYFISTLFIGSNMLFFPMHSLGMYAFPRRISDYPVSFLFWSSFMLYGMLLLASLILFLCALFCVFLFWDYCLFFVSLFVFSLYCFFYFSTWLPCVMVLYLLLVDFAHIVLDYLFLILCFCFVFFIFFWQSLFLFFYI  
s2:
.....................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPT..PGVRTAVKDA.FDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEV....HVLIRSPDTHPNLQR..................................................................................................................................................................................................................................................  
s1:
.....................................................................................ASCRTGRLPMPDD......PLFNSTHMHGLRHSSRIAGLGMIAVIWIMYEKLRHSHHYITYKGPENPFARIRHRRFPGGAFMFGWGNNGLNRDCGIKEFECWAGYTGKEYTYV  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........................................  
s1:
..................................................................................................................................VAKISSIERASTYLRFSTLRVHPHHEPNFRARPVGWKAWNSKQYMDPWAPYPLTSPVRHVDRPFSGMWFGMGHFALKNFFGPLNWKFWARVSFFGTLGWAYSLSSYALRMHRNGWEWKNRGAVF  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.................................................................................................  
s1:
..............................................................................................................................................KVLIADLPMMWPSDMRRFEKEGGVWGQQFRQRRRQLTFALTISAASTLLGSWYVVMRRRNTYFVLFSTFSGFSVLGFCIGMSLAPLWYENVANNKETSMMRRVWWAKECAKHWD  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRS.PDTHPNLQR..................................................................................................  
s1:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPR.......DGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKE.GRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALY..AEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s2:
.................................................................................................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAP.LYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMR..VPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLI..RSPDTHPNLQR.........................................................  
s1:
...........................TPYQDKSYPVQPHNLDELQQPPDSWRKSP.IMSKLMDQ.SLPVYDDV..VTGVGRLYWQEPARVWHLFEADDTLMLEEHDREEWNDRPYVAVNHLYEPPIGSEERPIRVEGTGNP..GDQQIVLCFGNCAPHVPQSNYYMMMKGYNKTKCPMCQQWFYIHNRPWLVMHPDWTDEPAADEGPAYTFSEIEAEFDRDFHEFGVYLNAE  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFN...DGPF..DNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.......................................................................  
s1:
.............................................................................AEARAVLQAQSHRTVSAVVPGKMFMRHWIVAEQSTVSVVNRVISGMVAVFTMIWAAGYATLGYNGHNSAHVAGWIFIAYWVVLHTHIMWLAPTML  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMR...VPYSAATTEILQAVAFNDGPFDN.SPLLFEMIEYPERGEVHV.....LIRSPDTHPNLQR......  
s1:
PGQLANYSSPLYMYSHLIKNSTAKTPQLYTAKDNSKTAMHLLTRRGATANYTVNRWYLKE.KVDSSNRMRLEGLYECVLCASCTGSCPQYWWNREHFLGPAVLLQSYRWLVEPLDRDFDERVRMFETGTLVNMCHNIFNCSITCPKFLNPGLASKEIKRLSSPAAKRVGPAIE..........  
s2:
................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILR..IGGETHAHAHRMALKILDDMNLMRV.PYSAATTEILQAVAFNDG....PFDNSPLLFEMIE...YPERGEVHVLIRSPDTHPNLQR  
s1:
.......................................EDHRKYKVQREELPRMPHFNDFNDPRFCGTTNKQKNGILAYYQWLHCIGNWGEEHSMCKKMRWYVERMMHETWLEKWEEKRALGHFDHTILYGVKPWKEFEPLYQPVKKNRKGAYEYWLDR.DFEPLYDADAADWREKAPILHDMFVLGKKPVA  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILR.......IG..GETHAHAHRMALKILDDMNLM...RVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR........................  
s1:
...............................................WPSKLPLTKNWYYHLSRRD....SIADETRQYMVVGDFLLLFVVSFSMYRLYVLNRNNTYQTHLSHLINYPPAIIANEFDFKDSNANRLVERKDLDAYREDVVRCRAS........  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPG..VRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFD....NSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
................YGHALELDTHNYKFNGEPPSWMKTHAKTEEETSFAKSVLPHIDFASSYECLLFDADRLNTNLNRKEFGNEIKYRLEKQANTVARAQQLLKDKKAGTGPDAAKIENTLIARIFDEEHVQAEMKYVKCIRANELAEDNRLDILPGGSPNSLREKTRWNLNTELHPADRAEIGARLTAWLPEKYHIVYFDDFQTVAANDATARREMLEIVESVQKEYTAEAKEGGYESDLKETVAELMDDVDPTRAITMEAIKSCKDLQQLEDWSRQVHEYNGDDRIIEIYARAAEITKNAEHQALVKQMREWRKLATK  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRF...APLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGET......HAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR............................................................................................................................................................  
s1:
...................................................................................................SLSTILYSPIGTSMMIMLAYNVIVICSKHVNYSLEITAKDYVQDQQLLTIMRYGILSCILLGMEVMFIEIG  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFN....DGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........  
s1:
..............PRPFGVWA...PATTLAEYRARIPNPFAYSFKWVYSMKREVFYPPEALAHFKDPQQFKDAVDTVIAMRVSDKIFGEGQKLP...RHPVILMLMVLATHGFIIFSGLKYYYGTYMPANNPTWRKTV...NKEWEEAINNSPWDHMSHVWQYSDEYAAALGDTAAPGQRKFYIPA  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPT...PGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPF..DNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........................  
s1:
.........................PATVKRPLWSLLLPQTYTSRIHTLAFHAPSILFMIAVCAIISKQSYYRSSLADE......DPKTYDRIDRRAYVALPDGRMALVYPIIDTQTSFTRTVISFLDAVNPF.................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTS.IEQQVAKRFS....KDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRV.P.YSAATTEILQAVAFND..GPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
IYTTWGSVPCEDWARNESWLKRITSQSDYRSFEFWHVPQADVPAGLRLNAVERYLLSSLENDTDRLLHVSWCEDFDPYWHDRVGSLEMLYKIVYTNDYPLYRYIFGNCMHKVAEKEYMLRKLNYLKSVLFWAGRTERCYTSIVKARYYVQRCVWNALERERYLCACVEAVDSFGKKVPEELRQKVMPELEVALVSMRHWVWDCPNGKRTFTRRLA...................................................................................................................  
s2:
.............................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
......SLADKIVRGPPKSVYYTHPRYVMSRDKMLHTIWVDIGIFQTCAYALFPFFSAAYFFK.....................................................................................................  
s2:
VNKVPASLLEKVCN..PRLVAFTAMDLARTRFAPLYT.....SIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..............TYMLAFNSKAKARPNFGLRGVGYWTSEVYHKPGQNYWMVVCCAGPFLLVGAIMMDGF.WSKLDDIAG....GGPSALDYGWRSQDRKPWDFSFDIGEGYAAGPAVYRPASGAVDL...................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRF....APLYTS.IEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGG.ETHAHAHRMALKILDDMNL.MRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
KAVLQLVRFDPETNSSRVESYEYDKHHEYMVLDLLIAVKAHQDPTLAFRSSCCEGVCGSCAMNINGINSLACITFAQHVTTVAPLPNFPVIKDFVVDLR.HFFQQYAYIRPYVRNANLHRSQVDGIVERYNTVARVLSGVSPSEGRAMEKAQEELRETTVAALLRIADAAVDAGNATQALSVLEKVEQQGVVLDSTRVTEMIERALKNFAAKS................................  
s2:
.................................................................................VNKVP..ASLLEKVCNPRLVAFTAMDLAR..TRFAPLYTSIEQQVAKRFSKDPSKLQP.TPGVRTAVKDAFDTSVCNDIANILRIG.GETHAHAHRMALKILDDMNLMRVPY.SAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
....YETFTPKTLSGRLVMPGNINL..LTVSPLYCAVLCIAAATWGVFYWDIYCRKNYETVLIARPKDM............................................................................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRT....AVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
MFVRVIFVGVSGVFVFLSLPAICIVYLTFCLCGLFCIMFGSFIFIDYCFICFFACLLFCLVCLLCDLFVDSLRGLFDVCCFIRCIQYCFVWFIISELLLFLSLFYVVFSLVLFVSVEFAFVFVIPVMFSCLICDFGFVFYWYFIDIFNLLINTFLLFVSGLFVNFVLFLFWFRFFLCVLFMLWVGILFGFLFLWNQVWEFALLFVTCSCGVFGSILFLIDLLHFSHVFLGIFLLFLCFSRCFNFLCMD...TRFVFLYVVCLYWHFVDCVWFFLLRFVYFDVLSVV........................................................................................................  
s2:
................................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLY........TSIEQQVAKRFSK.DPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
MFLGGFVPRRFTQLNRDPWWMFFIFSVGAWIGEYPAMQIKYNARDLVLDPHRYVWSHLDDHH..................................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
MGHEETTFSRGNRTRNNALQHIYGLMGLCGVGCVLALFSFVSGQRRIQTTITADGTMTKGTC.PT......................................................................................................  
s2:
..........VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
MAFILSFWMIFLLDSVIVLLSFVCFVCVWICALLFSTVLLVSKLNNIYCTWDFTASKFIDVYWFTIGGMFSLGLLLRLCLLLYFGHLNFVSFDLCKVVGFQWYWVYFIFGETTIFSNLILESDYMIGDLRLLQCNHVLTLLSLVIYKLWLSAVDVIHSFAISSLGVKVDCIPGRCNEIVLFSSNNATVYGQCSELCGVLHGFMPIVICFI.......................................................................................................................  
s2:
.......................................................................................................................................................................VNKVPASLLEKV...CNPRLVAFTAMDLARTR..FAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
YTRWKCDRIPVLQLKLFTQEYNIMALVGLLSMVFLFKHASYCSEETERKNGWWAGYPYWRDPIARRNEIRYKQLINSNDVDITDPKWTG..CSKEQ......................................................................................................................  
s2:
.........................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..............TYMLAFNSKAKARPNFGLRGVGYWTSEVYHKPGQNYWMVVCCAGPFLLVGAIMMDGF.WSKLDDIAG....GGPSALDYGWRSQDRKPWDFSFDIGEGYAAGPAVYRPASGAVDL...................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRF....APLYTS.IEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGG.ETHAHAHRMALKILDDMNL.MRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
.................................................................................................TMNFGNMTLGGA....MATFGGQSNPMCNYTSPLAKKFV.YKEVGKVHYPLRRHVFRTKVRTAAEIRFNEIVKRYMKEKMTFKRGCYAATITNTVELDHMGSIIPKDEYEVKRLTSYMTSKKMSSDYKKHMQELWTRVLFVCESTNLVGVTENAMHQNSRPGTDEEFMSIIWYSSFVTTLMAFVVTLFIWWYRYGQAPQYAEF  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDN..SPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.............................................................................................................................................  
s1:
................YGHALELDTHNYKFNGEPPSWMKTHAKTEEETSFAKSVLPHIDFASSYECLLFDADRLNTNLNRKEFGNEIKYRLEKQANTVARAQQLLKDKKAGTGPDAAKIENTLIARIFDEEHVQAEMKYVKCIRANELAEDNRLDILPGGSPNSLREKTRWNLNTELHPADRAEIGARLTAWLPEKYHIVYFDDFQTVAANDATARREMLEIVESVQKEYTAEAKEGGYESDLKETVAELMDDVDPTRAITMEAIKSCKDLQQLEDWSRQVHEYNGDDRIIEIYARAAEITKNAEHQALVKQMREWRKLATK  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRF...APLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGET......HAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR............................................................................................................................................................  
s1:
FFGKGWDNAALDTIFSSMLRKPEVNDRIRTQYASTMDPRDADVLRRLGEVSKENKTFIRVFLPPHLGDPHRLLKCYSLMAYPILDDKGGQLKVEMDGCKLDAFADPDDDYSKVVIPHIELVEYLAKSLLETMKWEATPRGAASLLESLYRGAEIPDHVFQTPAVIERLEDYKDGNKVIS.......................................................................................................  
s2:
........................................................................................................................VNKVPASLLEKV...CNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFS..KDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
.....................................................................................LHFPLSPPPIEIDY.LDSDPLEFAVRTEARRWGFDDLQYMRELAFVRIKENPSIGDFRRM..TPEERRDLFWGSDRQDFFRYITLKLTGHPEHLYHRGW  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR...........................  
s1:
...........................TPYQDKSYPVQPHNLDELQQPPDSWRKSPIMSKLMDQSL..PVYDDV..VTGVGRLYWQEPARVWHLFEADDTLMLEEHDREEWNDRPYVAVNHLYEPPIGSEERPIRVEGTGNP..GDQQIVLCFGNCAPHVPQSNYYMMMKGYNKTKCPMCQQWFYIHNRPWLVMHPDWTDEPAADEGPAYTFSEIEAEFDRDFHEFGVYLNAE  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFN...DGPF..DNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.......................................................................  
s1:
MFWLCLVCLSVSHKMIGLCYLLVAILSGFVGYVYSLFIRLELSLIGCGILFGDYQFYNVLITSHGLIMVFAFIMPVMMGGLVNYFIPVMAGFPDMVFPRLNNMSFWMYLAGFGCVVNGFLTEEGMGVGWTLYPTLICIDFHSSLACDFVMFAVHLLGISSILNSINLLGTLFCCRRKFFSFLSWSLFIWAALITAILLIITLPVLAGGVTLILCDRNFNTSFYDVVG.....GGDLILFQHIFWFFGHPEVYIILLPVFGLISTIVEVIGFR.CVFSTVAMIYSMILIAILGMFVWAHHMFVVGMDVDSRAYFGGVSILIGLPTCVKLFNWIYSFLYTDMIITFEVYFVIMFIFMFLIGAVTGLFLSNVGIDIMLHDTYFVVGHFHYVLSLGAVVGFFTGFIHFLAKWLPIELYLFWMFYFISTLFIGSNMLFFPMHSLGMYAFPRRISDYPVSFLFWSSFMLYGMLLLASLILFLCALFCVFLFWDYCLFFVSLFVFSLYCFFYFSTWLPCVMVLYLLLVDFAHIVLDYLFLILCFCFVFFIFFWQSLFLFFYI  
s2:
.....................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPT..PGVRTAVKDA.FDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEV....HVLIRSPDTHPNLQR..................................................................................................................................................................................................................................................  
s1:
MFVRVIFVGVSGVFVFLSLPAICIVYLTFCLCGLFCIMFGSFIFIDYCFICFFACLLFCLVCLLCDLFVDSLRGLFDVCCFIRCIQYCFVWFIISELLLFLSLFYVVFSLVLFVSVEFAFVFVIPVMFSCLICDFGFVFYWYFIDIFNLLINTFLLFVSGLFVNFVLFLFWFRFFLCVLFMLWVGILFGFLFLWNQVWEFALLFVTCSCGVFGSILFLIDLLHFSHVFLGIFLLFLCFSRCFNFLCMD...TRFVFLYVVCLYWHFVDCVWFFLLRFVYFDVLSVV........................................................................................................  
s2:
................................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLY........TSIEQQVAKRFSK.DPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..................................................................................................................................VAKISSIERASTYLRFSTLRVHPHHEPNFRARPVGWKAWNSKQYMDPWAPYPLTSPVRHVDRPFSGMWFGMGHFALKNFFGPLNWKFWARVSFFGTLGWAYSLSSYALRMHRNGWEWKNRGAVF  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.................................................................................................  
s1:
..........................................................DMHSSDRFKAA.WDEIP..LHMLGASHKQMFEWYWRAMYQLGL.RDPYRLT...KLRSMLNWAALFSFMYLTYISIFYSSFYHVYMM....DWPEHFKRENAREYALSHGHDVWAGDGKFIRPYFHINPPMLTMTSEDI  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR........................................  
s1:
MAFILSFWMIFLLDSVIVLLSFVCFVCVWICALLFSTVLLVSKLNNIYCTWDFTASKFIDVYWFTIGGMFSLGLLLRLCLLLYFGHLNFVSFDLCKVVGFQWYWVYFIFGETTIFSNLILESDYMIGDLRLLQCNHVLTLLSLVIYKLWLSAVDVIHSFAISSLGVKVDCIPGRCNEIVLFSSNNATVYGQCSELCGVLHGFMPIVICFI.......................................................................................................................  
s2:
.......................................................................................................................................................................VNKVPASLLEKV...CNPRLVAFTAMDLARTR..FAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
SRVSNKISGGMACQTVVNHGYYLKPMTGNPYLCTQHDGVTTAYQQGFAPKDFNWLYRFRYNLLPQGMSGGFFSRNPYGRYVHWLEVSTIEKMRLQMFTMESVPCSVVSLILLVFTMWHSYRLAFLHPDITLYNLG.LWSTKPWVQQQRFNKKKELDQDVYRWMTRVPEVMMDDPIREMYK.MGITANDPVYAMAKEQGVEHELTMTHAEYTSTSPDIRRVIANARK...................................  
s2:
..................................................................................................VNKVPASLLEKVC......NPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..........................................................................TYFYANCGETGISGATMQVLLKLTLACCVVQVFAIRYFVFQRLTTKKQFVEDSTDLWESDGTEMDGEEAVANLRIQHERIMPFMNDIKDKLDAQ  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGE...VHVLIRSPDTHPNLQR........  
s1:
.....................YTELSHMKF.PVYYGAVGVVLGYFVVMWVVFLRMGSKHTA.RSEFKNDYLRVWRRRLGTGYEWADAWGPEMGTFFKDLPEE........................................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGE.THAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
.......................................EDHRKYKVQREELPRMPHFNDFNDPRFCGTTNKQKNGILAYYQWLHCIGNWGEEHSMCKKMRWYVERMMHETWLEKWEEKRALGHFDHTILYGVKPWKEFEPLYQPVKKNRKGAYEYWLDR.DFEPLYDADAADWREKAPILHDMFVLGKKPVA  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILR.......IG..GETHAHAHRMALKILDDMNLM...RVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR........................  
s1:
.....................................................................................ASCRTGRLPMPDD......PLFNSTHMHGLRHSSRIAGLGMIAVIWIMYEKLRHSHHYITYKGPENPFARIRHRRFPGGAFMFGWGNNGLNRDCGIKEFECWAGYTGKEYTYV  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........................................  
s1:
..............PRPFGVWA...PATTLAEYRARIPNPFAYSFKWVYSMKREVFYPPEALAHFKDPQQFKDAVDTVIAMRVSDKIFGEGQKLP...RHPVILMLMVLATHGFIIFSGLKYYYGTYMPANNPTWRKTVNKEWEEAIN...NSPWDHMSHVWQYSDEYAAALGDTAAPGQRKFYIPA  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPT...PGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPF..DNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........................  
s1:
MLRRHAYKTAACVTAIQVARAVHSIAVLQNSTPATTAQKLGSVVSKEEVAAVNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLIATITDEVDYTSIEQQVAKRFSKDPSKLQPTPGALKHFRENNWKDMKSLITFYEETMYPIRMKHKEYKYHELTSFHIKDVLKRGLSAFKQSYLDEQREEQTKVKAYMKSCDDFVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVGTASLENISDEVLKLISNRHQTPLDDGVLIRSPDTHPNLQRSPE  
s2:
...................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPL.........YTSIEQQVAKRFSKDPSKLQPTPG................................................................................VRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVH............................VLIRSPDTHPNLQR...  

> matchmaker #6/L3 to #1.2/L3

Computing secondary structure  
Parameters  
---  
Chain pairing | bb  
Alignment algorithm | Needleman-Wunsch  
Similarity matrix | BLOSUM-62  
SS fraction | 0.3  
Gap open (HH/SS/other) | 18/18/6  
Gap extend | 1  
SS matrix |  |  | H | S | O  
---|---|---|---  
H | 6 | -9 | -6  
S |  | 6 | -6  
O |  |  | 4  
Iteration cutoff | 2  
  
Matchmaker copy of combination, chain L3 (#1.2) with chainL3.cif, chain L3
(#6), sequence alignment score = 562.7  
RMSD between 77 pruned atom pairs is 1.065 angstroms; (across all 157 pairs:
26.079)  
  
Computing secondary structure  
s1:
ASKEEQIKKNTKIAIEMIRRYKGETPMSYTRKHTATIEQLEREIEALLGGAQKMRKATTDDQPMDKLGLMERCLRHALWSYHKDEGKYDFDEIARWVVYTPEDEVKLAQMKRQVEAKSKLAAYRAKRAEQGLPEAPVPQISWEEEYKNVTDRELVNEKRLRYDTIAANTMERDEAQIEAVLQQYRKPIQDKRLDDLVDLLERFKPVLAREAIMQRLTIKHLEGQLGVWRYMDWCPEVRDRAELEVDISGFQWWSPLEERRLLPVRLRSVNEVREIMAQTQSSKAAEASAHSPQASQSAGDGDRERLLKEVLALQARIHQRDDAP  
s2:
.............................VNKVPASL..LEKVCNPRLVAFTAMDLARTRFAP.....LYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVL..IRSPDTHPNLQR.................................................................................................................................  
s1:
PAEHKGRVGYVSQVIGAVVDVHFSEGVPPVLTALDVTEDLGRDEPLTLEIVQHLDANTGRCIAMQTTDLLKLKSKVVSTGGNISVPVGRETLGRIFNVLGDAIDQRGPVGEKMRMAIHAEAPKLADQAAEDTILTTGIKVIDLILPYCKGGKIGLFGGAGVGKTVIIMELINNVAKGHGGFSVFAGVGERTREGTDLYLEMMQSKVIDLKGDSKCVLVYGQMNEPPGARARVAQSALTMAEYFRDVEGQNVLLFIDNIFRFTQANSEVSALLGRIPAAVGYQPTLAEDLGMLQERITSTTKGSITSVQAVYVPADDITDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMDPDVIDVNHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQVAEVFTGMTGHYVQLNDTVESFSGLLMGSYDQIPEMAFYMVGGINSVLEKAKAMAEEAAAMEK  
s2:
....................................................................................................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQP..TP...GVRTAVKDAFDT...SVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........................  
s1:
FFGKGWDNAALDTIFSSMLRKPEVNDRIRTQYASTMDPRDADVLRRLGEVSKENKTFIRVFLPPHLGDPHRLLKCYSLMAYPILDDKGGQLKVEMDGCKLDAFADPDDDYSKVVIPHIELVEYLAKSLLETMKWEATPRGAASLLESLYRGAEIPDHVFQTPAVIERLEDYKDGNKVIS.......................................................................................................  
s2:
........................................................................................................................VNKVPASLLEKV...CNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFS..KDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
KATEMIGYVHSIDGTIATLIPAPGNPGVAYNTIIMIQVSPTTFAAGLVFNLEKDGRIGIILMDNITEVQSGQKVMATGKLLYIPVGAGVLGKVVNPLGHEVPVGLQTLGKVDAGAPNIVSRSPVNYNLLTGFKAVDTMIPIGRGQRELIVGDRQTGKTSIAVSTIINQVRNNQQI......LSKNAVISIYVSIGQR.CSNVARIHRLLRSYGALRYTTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNVAMKAVAGKLKGILAEYRKLAADQVQTVPMIRGARFVALFNQKNPSFFMNALVSLYACLNGYLDDVKVNYAKLYEYLLVNKDLSVMYGTATNKFFYMYVQQLNYVIRFFTLNHPILNAEVEEMLKQHTHLFLQHYQSKMNAIKTEKEIKALKNLLYSCKRAV  
s2:
.............................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVR.TAVKDA..FDTSVCNDIANILRIG.GETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIE.....YPERGEVHV.LIRSPDTHPNLQR...............................................................................................................................................................................................................  
s1:
EHKGRVGYVSQVIGAVVDVHFSEGVPPVLTALDVTEDLGRDEPLTLEIVQHLDANTGRCIAMQTTDLLKLKSKVVSTGGNISVPVGRETLGRIFNVLGDAIDQRGPVGEKMRMAIHAEAPKLADQAAEDTILTTGIKVIDLILPYCKGGKIGLFGGAGVGKTVIIMELINNVAKGHGGFSVFAGVGERTREGTDLYLEMMQSKVIDLKGDSKCVLVYGQMNEPPGARARVAQSALTMAEYFRDVEGQN...VLLFIDN..IFRFTQANSEVSALLG.RIPAAVGYQPTLAEDLGMLQERITSTTKGSITSVQAVYVTDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMDPDVIDVNHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQVAEVFTGMTGHYVQLNDTVESFSGLLMGSYDQIPEMAFYMVGGINSVLEKAKAMAEEAAAMEKQRRAR  
s2:
...........................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANIL.RIGGET.HAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFND.GPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR...........................................................................................................  
s1:
KGRVGYVSQVIGAVVDVHFSEGVPPVLTALDVTEDLGRDEPLTLEIVQHLDANTGRCIAMQTTDLLKLKSKVVSTGGNISVPVGRETLGRIFNVLGDAIDQRGPVGEKMRMAIHAEAPKLADQAAEDTILTTGIKVIDLILPYCKGGKIGLFGGAGVGKTVIIMELINNVAKGHGGFSVFAGVGERTREGTDLYLEMMQSKVIDLKGDSKCVLVYGQMNEPPGARARVAQSALTMAEYFRDVEGQNVLLFIDNIFRFTQANSEVSALLGRIPAAVGYQPTLAEDLGMLQERITSTTKGSITSVQAVYVPADDITDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMDPDVIDVNHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQVAEVFTGMTGHYVQLNDTVESFSGLLMGSYDQIPEMAFYMVGGINSVLEKAKAMAEEAAAMEENKAAH  
s2:
................................................................................................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQP..TP...GVRTAVKDAFDT...SVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR..............................  
s1:
.............................................................KYDLFGYEV..DTNTAPWIEKVKKCRYYDEAGEVLVSMNVKNCPPDLETYNATLQKIFEAPSKQEKPVENESKFCAMMDLMEEMQHRNKVK.....PNEESWTWVMKECVQSGQFRLGYCVAKLMEAEFKRVPEDLVKQNEANAAKAKADGKEHPSTLAQQQSLFDIKIQ  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVP.....YSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.....................................................................  
s1:
.....................................................................................LHFPLSPPPIEIDY.LDSDPLEFAVRTEARRWGFDDLQYMRELAFVRIKENPSIGDFRRM..TPEERRDLFWGSDRQDFFRYITLKLTGHPEHLYHRGW  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR...........................  
s1:
ASDLKMVSLHKILIGEVQFRNNALLKACNIEHNFGPTWKSEIEAYAKSLPAEEKNCLERQIARVSMTRYTTRELAEYCGEGPEHVDAVAREANIAQAKVYAQKNGADKLETYVKAEAKNA....GWSEAETK....KFMDAVKAAK......................................................  
s2:
.........................................VNKVPASL..LEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
...........................................................AKKYDLFGYEVDTNTAP..WIEKVKKCRYYDEAGEVLVSMNVKNCPPDLETYNATLQKIFEAPSKQEKPVENESKFCAMMDLMEEMQHRNKVK.....PNEESWTWVMKECVQSGQFRLGYCVAKLMEAEFKRVPEDLVKQNEANAAKAKADGKEHPSTLAQQQSLFDIKIQ  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVP.....YSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.....................................................................  
s1:
TEMIGYVHSIDGTIATLIPAPGNPGVAYNTIIMIQVSPTTFAAGLVFNLEKDGRIGIILMDNITEVQSGQKVMATGKLLYIPVGAGVLGKVVNPLGHEVPVGQTLGKVDAGAPNIVSRSPVNYNLLTGFKAVDTMIPIGRGQRELIVGDRQTGKTSIAVSTIINQVRNNQQI......LSKNAVISIYVSIGQR.CSNVARIHRLLRSYGALRYTTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNVAMKAVAGKLKGILAEYRKLAADVQTVPMIRGARFVALFNQKNPSFFMNALVSLYACLNGYLDDVKVNYAKLYEYLLVNKDLSVMYGTATNKFFYMYVQQLNYVIRFFTLNHPILNAEVEEMLKQHTHLFLQHYQSKMNAIKTEKEIKALKNLLYSCKRAV  
s2:
..........................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVR.TAVKDA..FDTSVCNDIANILRIG.GETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIE.....YPERGEVHV.LIRSPDTHPNLQR..............................................................................................................................................................................................................  
s1:
........................................................GAKK..YDLFGYEV..DTNTAPWIEKVKKCRYYDEAGEVLVSMNVKNCPPDLETYNATLQKIFEAPSKQEKPVENESKFCAMMDLMEEMQHRNKVK.....PNEESWTWVMKECVQSGQFRLGYCVAKLMEAEFKRVPEDLVKQNEANAAKAKADGKEHPSTLAQQQSLFDIKIQ  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVP.....YSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.....................................................................  
s1:
SIAVIAAGAPAALLQAVSSILSKATGGAVKATQATSAA.SNAVVVGMQAPRGVYACVAEPPSTASGPYAGVKTVVVRAILPRSAPDTMQVRDILDVYPASGIACEKETAEAVKNFTKAAKVAVEKAKAMKATRVTLVMKPATKYERLNGLFRETCTKTIEAAGLSVETSTTAAATNTLIMFPEK..MSVVMVSDDPVCENVQYAYAGAVGGVHTTYYTDSGNKIYGGHSYRSVAMALAEELKSLGMKAEAAKVEAAVQKSPRNAAAAM  
s2:
............VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQ.PTPGVRTAVKDAF......DTSVCNDIANILRIGG.....ET......HAHAHRMALKILDDMNLMRVP...............YSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPD.THPNLQR.................................................................  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
..................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
SIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
..................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
..................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
..................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..........YTPSEELKKLYASDFERAQFP...ANIVPSDSVTFAKFLYKAVEPKGSFDAILKDFQTIAAAIPK..LPIFWERTV........VVSEVNEFK.SLSAPTIFTLEWMQSN.GMLDLLPDVAEVYETYVSAKMKRVTAKIYVAPGKEQDRALVDKARKVAEQVVKDNKQLAGYTLVPKVLVDRSIVEGFAVDVQGTYVNEAVGRKIETEVLRKYLDSLSLYDAEELKSGV  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR..................................................................................  
s1:
VALNWRDHGISYVKYLNVATEALHMATKDKARAKYSRFSTPNYIALVKKVPAFT.....................................................................................................................................................  
s2:
..............................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
FFKATEMIGYVHSIDGTIATLIPAPGNPGVAYNTIIMIQVSPTTFAAGLVFNLEKDGRIGIILMDNITEVQSGQKVMATGKLLYIPVGAGVLGKVVNPLGHEVPVGLQTLGKVDAGAPNIVSRSPVNYNLLTGFKAVDTMIPIGRGQRELIVGDRQTGKTSIAVSTIINQVRNNQQI......LSKNAVISIYVSIGQR.CSNVARIHRLLRSYGALRYTTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNVAMKAVAGKLKGILAEYRKLAAQTVPMIRGARFVALFNQKNPSFFMNALVSLYACLNGYLDDVKVNYAKLYEYLLVNKDLSVMYGTATNKFFYMYVQQLNYVIRFFTLNHPILNAEVEEMLKQHTHLFLQHYQSKMNAIKTEKEIKALKNLLYSCKRAVG  
s2:
...............................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVR.TAVKDA..FDTSVCNDIANILRIG.GETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIE.....YPERGEVHV.LIRSPDTHPNLQR.............................................................................................................................................................................................................  
s1:
LSLLLCVHFSAIHR..PPPPVPFTALA......AFLYALTLTAPVAEQRS..GSSLHPQIEVGTEIEDMALFHLVVLPLVFFAAMCIGRG.........................................................................  
s2:
...VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYT.SIEQQVAKRFSKDPSKLQPTPGVRTAVKD..AFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
QMKVELTMQYLDEWMLRWRKFQTESDWQIEKNRQWWRKANIVTAGAVMGGLVMYTAGNATIRRQFGAPHFFDIGVDGKLKEAICDTMTSRWRYTPQGYGRVMLVGLPTFFVFAISEHIQERRRLRAYVRQNTVFGEQARRLVQNGKIEEYLAVDIKASLP.QNQTQLYAG....................................................................  
s2:
.......................................................................VNKVPASLLEKVCN..PRLVAFTAMDLARTRFAPLYT....SIEQQVAKRFSKDPSKLQPT...PGVRTAVKDA.FDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
.............................................................................................................................................NMFLFKDPVRRPQLSPEERAKVKINYAEWPEEFRDYDPDDPYKNSPEIIEGLSSWNLFLWGVECAFIYQFYEVVFPKS  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR..............................................................  
s1:
....................NPVDHFRPNLKFLSVYVEHQYVVDKWLHVKENWLKPWYLPWW.TPMYQAM.TWYSQRNRNLMLVENHLNYRPYRYRRNDEDREN....PY...................................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLAR..TRFAPLYTSIEQQVAKRFSKDPSKLQP..TPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
VFFSTYRSKRIVAPGFLKGPVMASRAFFDYYFQRAWCGCVQWVIPGEVRLWACGVPVIYFIHRYHNDHSLEPDFVEKAMIQRWGG..SLEEVR.KLSPQDQLRIRAFTDLEKLYSAYGPKD.TIVQP.PGDLLPGKDYYH..........................................................................................  
s2:
..................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAP.......LYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
GTWSVLKKNCLNFVPGLALFASQSRDAFATWMKIYNRGYKYGPQEFSDQAEAYTPDYWKRGHSQEKNMWVDMKLSEEVSQKELAQLMHYKQDLWRMGHGLGLSLFLGGYALIPAFFCLSSDTFAPSCFCKTEEEKKAWREAQDMYRYRSAPSYIMDTKWHFD.FHAYPWN....ATQERAWDDLFEKNNVRRDPKVLRPAAEMYDGFLKFYQIRRKSLRHLARSMNLPTFPLLSRTCASTRVKDYWNLAWNEDYMVITQKLHHQMSDEDLHDYAWRRFLAPYDKNLSRDEIMTRVNDYHEFLGPKFVEEGKAPNMIILTNYVLGYYNDPAYLVEDISALDGNDFEYMAHYGKDAFLRRLEFENGPLRDQVEAHTQKLIADRAAAAAAEA  
s2:
.......................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.................................................................................................................  
s1:
HLEPMSVWYLSSWTCVWWYSFFFWLPVLWADMIVPSFVYNKLPVIHFIQEKRAEQKLRRVLDETYTQ................................................................................................................................  
s2:
......................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
...............................................HPPKLEDIP.PSSATKGFFGAYMARLIDIKWMMNRSVELGREYYISAPTLYLFLWMFCWKGFVIMRYGDGKPP.............................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCN..DIANIL....RIGGE..THAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
................................................................................................................VGNGPTFHTAGDNNNTSEIQNAFPINERG...IRSSSPFPEPNTAIYDSYMPWTYFQPIDVKVDKMPAPEAKYYQHHTKKPWDVSTTDLIEIQSRKKYVQGVGYFLMMIYLYFLMPKEKSYSGTTGSDGFYVMLPKNQPEKFV  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFND.GPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.................................................................................................  
s1:
MFVFFVCDLVIMRILLCFCYSVWSRIIFVLFYNVFYICTELMFCIFDVYLFVGLCMFICLWFVLFNFYGLIVYYCITYLNVYILFCIVFMYYMAFLFCFCFLLDFILFGSLLVGDAFMDVFFLRYLLCVLECFSLLCRCISTFLRMFCNLLSSHFLMLMFCDFVYFFIIFFLFFIMCDFIYFIIFTFAMLFCIIFYLFLYALDMFCALLQIFIFCNMIMQLIMDFLL...LLSFHG.......................................................................................................................................  
s2:
......................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
FTVPVALCTKQVAAMDEPLKRHIDAYEARGEDVTIAVWREYVDGQRALLPYRWAKFRNEVTYLTSGQIALTDLAFADLLLFVRFLTKCLFIFIVAVMAGRRSVFPS.LEPTSPFVEEIVKN.WQPNRLRRVAGAEYMARDQAAAAAAAAA................................................................  
s2:
........................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPT.PGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
........................................................................................................PKTLNQFRNFSYIVVAWLGFNKGFREKAANDAEWIAHQQRVRQQNVERHQAASAMMEA  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVP.....YSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..........................................................................................VAPKTLN.......QFRNFSYIVVAWLGFNKGFREKAANDAEWIAHQQRVRQQNV............  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
AFHDVSTDAIRQMQASEALQKHLENAQLAHRVCVAKALKADEPPVEK.CALTWGEVVMRYNQWSEYRPAFHDSDAQ..KRYSKYWTKKRQA......................................................................................................  
s2:
....................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
SRVSNKISGGMACQTVVNHGYYLKPMTGNPYLCTQHDGVTTAYQQGFAPKDFNWLYRFRYNLLPQGMSGGFFSRNPYGRYVHWLEVSTIEKMRLQMFTMESVPCSVVSLILLVFTMWHSYRLAFLHPDITLYNLG.LWSTKPWVQQQRFNKKKELDQDVYRWMTRVPEVMMDDPIREMYKM.GITANDPVYAMAKEQGVEHELTMTHAEYTSTSPDIRRVIANARK...................................  
s2:
..................................................................................................VNKVPASLLEKVC......NPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..................KLYASDFERAQFPANIVPSDSVTFAKFLYKA...VEP........KGSFD.AILKDFQTIAAAIPKLPIFWERTV..VVSEVNEFK.SLSAPTIFTLEWMQSN.GMLDLLPDVAEVYETYVSAKMKRVTAKIYVAPGKEQDRALVDKARKVAEQVVKDNKQLAGYTLVPKVLVDRSIVEGFAVDVVNEAVG  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRF.APLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR...................................................  
s1:
SGRLRLYKEKLEGYNRFYSIVKTIKMVTMAKFRQAQVRIKTRDYTL..RYTEKAFSKPGQLVGDSPQAKAIYIPVMTNRGSCGALNSNVVKVIDSVASSRAYLMPLGKRGIESLSKLYPSSFRMGIVNDM.HEPMHFAYATYVWENAQQLCPEADRVHIIFHRCVSAGSQKQCYYNIPAYEKWKEDLVDASSTENQKSRYLFANTLLNEDEQMIRDFYDFHATLAILNAVCENELSEQAARLVAVEGQLSNISTLQQKTSSLYNKTRQSSITSSLIEIISAMTSLEGNAAKGVQRTN  
s2:
.......VNKVPA..SLLEKVCNPRLVAFTAMDLARTRFAPL.YTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAF.DTSVCN.DIANILR.IGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEY..PERGEVHVLIRSPDTHPNLQR.............................................................................................................................  
s1:
.....YTELSHMKFP..VYYGAVGVVLGYFVVMWVVFLRMGSKHTARSEFKNDYLRVWRRRLGTGYEWADAWGPEMGTFFKDLPEE.........................................................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVC..NDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..........................................................DMHSSDRFKAA.WDEIP..LHMLGASHKQMFEWYWRAMYQLGL.RDPYRLT...KLRSMLNWAALFSFMYLTYISIFYSSFYHVYMM....DWPEHFKRENAREYALSHGHDVWAGDGKFIRPYFHINPPMLTMTSEDI  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR........................................  
s1:
..........................................................................TYFYANCGETGISGATMQVLLKLTLACCVVQVFAIRYFVFQRLTTKKQFVEDSTDLWESDGTEMDGEEAVANLRIQHERIMPFMNDIKDKLDAQ  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGE...VHVLIRSPDTHPNLQR........  
s1:
.................................................................................................TMNFGNMTLGGA....MATFGGQSNPMCNYTSPLAKKFV.YKEVGKVHYPLRRHVFRTKVRTAAEIRFNEIVKRYMKEKMTFKRGCYAATITNTVELDHMGSIIPKDEYEVKRLTSYMTSKKMSSDYKKHMQELWTRVLFVCESTNLVGVTENAMHQNSRPGTDEEFMSIIWYSSFVTTLMAFVVTLFIWWYRYGQAPQYAEF  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDN..SPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.............................................................................................................................................  
s1:
............................ELPEAFEFIEHKVTDKDIHSAYENMETLRLTVTRQDEFLFKETPVKCVTIVGVNGENGVYPGHAYEI.TQLTPAPLTVEMP.DGTVKKFFTSGGFAHINNEGSCDINCVECIPLAELDLDAAEKALAQQQSALSSAHDEKAKAVIEIRIGVLESVIQSLKHMKE  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAF...DTSV.CNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAF....NDGPFD.N....SPLLFEMIEYPERGEVHVLIRSPDTHPNLQR......................  
s1:
PLATLKPVLAESVATQNVIRRMIGVTTNRKVNASAINSVAEKTKGEGLAGTTAVVARAHLYLLSRNPTDAVAEIDAVLPKVQDEALRRFAIGIRLRSHNELLDMKEASLGVSGGATESEVSDLRSKLQKDYKELVTSSPGCWLVELAAAEYTLYTGASEEAYKSFSSIEKKIQEYIKAPIHVSELVATADNTNEFSLIGFQVRRARPGVKPEGVSASVAEGMANVMADPAAVKALQQAKKAFEEALELVVTLQEANV....GH...HFHDFFPTTPDHYDKWTSEAARSAQQLIQE.ALTPHSVGLKPEAIDRIRVSMTNKAFYDSEEKLHALLKSAPKDKSIIASIRETFGPGPSTPISSSDQAVADAVESVHLAVVSSDTAGATDYAKRGKEIAKALAKQLLYRTQVQKCVALTEMNCLQEAVDVVTPVIDANEYIYMWRAFLARSRAYKGLGLITNADKDLKELNRLKHSLTERTPYEKK  
s2:
..............................................................................................................................................................................VNKVPASLLEKVC...NPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSK...DPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIE........YPERGEVHVLIRSPDTHPNLQR..........................................................................................................................................  
s1:
MFWLCLVCLSVSHKMIGLCYLLVAILSGFVGYVYSLFIRLELSLIGCGILFGDYQFYNVLITSHGLIMVFAFIMPVMMGGLVNYFIPVMAGFPDMVFPRLNNMSFWMYLAGFGCVVNGFLTEEGMGVGWTLYPTLICIDFHSSLACDFVMFAVHLLGISSILNSINLLGTLFCCRRKFFSFLSWSLFIWAALITAILLIITLPVLAGGVTLILCDRNFNTSFYDVVG.....GGDLILFQHIFWFFGHPEVYIILLPVFGLISTIVEVIGFR.CVFSTVAMIYSMILIAILGMFVWAHHMFVVGMDVDSRAYFGGVSILIGLPTCVKLFNWIYSFLYTDMIITFEVYFVIMFIFMFLIGAVTGLFLSNVGIDIMLHDTYFVVGHFHYVLSLGAVVGFFTGFIHFLAKWLPIELYLFWMFYFISTLFIGSNMLFFPMHSLGMYAFPRRISDYPVSFLFWSSFMLYGMLLLASLILFLCALFCVFLFWDYCLFFVSLFVFSLYCFFYFSTWLPCVMVLYLLLVDFAHIVLDYLFLILCFCFVFFIFFWQSLFLFFYI  
s2:
.....................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPT..PGVRTAVKDA.FDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEV....HVLIRSPDTHPNLQR..................................................................................................................................................................................................................................................  
s1:
.....................................................................................ASCRTGRLPMPDD......PLFNSTHMHGLRHSSRIAGLGMIAVIWIMYEKLRHSHHYITYKGPENPFARIRHRRFPGGAFMFGWGNNGLNRDCGIKEFECWAGYTGKEYTYV  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........................................  
s1:
..................................................................................................................................VAKISSIERASTYLRFSTLRVHPHHEPNFRARPVGWKAWNSKQYMDPWAPYPLTSPVRHVDRPFSGMWFGMGHFALKNFFGPLNWKFWARVSFFGTLGWAYSLSSYALRMHRNGWEWKNRGAVF  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.................................................................................................  
s1:
..............................................................................................................................................KVLIADLPMMWPSDMRRFEKEGGVWGQQFRQRRRQLTFALTISAASTLLGSWYVVMRRRNTYFVLFSTFSGFSVLGFCIGMSLAPLWYENVANNKETSMMRRVWWAKECAKHWD  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRS.PDTHPNLQR..................................................................................................  
s1:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPR.......DGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKE.GRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALY..AEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s2:
.................................................................................................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAP.LYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMR..VPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLI..RSPDTHPNLQR.........................................................  
s1:
...........................TPYQDKSYPVQPHNLDELQQPPDSWRKSP.IMSKLMDQ.SLPVYDDV..VTGVGRLYWQEPARVWHLFEADDTLMLEEHDREEWNDRPYVAVNHLYEPPIGSEERPIRVEGTGNP..GDQQIVLCFGNCAPHVPQSNYYMMMKGYNKTKCPMCQQWFYIHNRPWLVMHPDWTDEPAADEGPAYTFSEIEAEFDRDFHEFGVYLNAE  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFN...DGPF..DNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.......................................................................  
s1:
.............................................................................AEARAVLQAQSHRTVSAVVPGKMFMRHWIVAEQSTVSVVNRVISGMVAVFTMIWAAGYATLGYNGHNSAHVAGWIFIAYWVVLHTHIMWLAPTML  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMR...VPYSAATTEILQAVAFNDGPFDN.SPLLFEMIEYPERGEVHV.....LIRSPDTHPNLQR......  
s1:
PGQLANYSSPLYMYSHLIKNSTAKTPQLYTAKDNSKTAMHLLTRRGATANYTVNRWYLKE.KVDSSNRMRLEGLYECVLCASCTGSCPQYWWNREHFLGPAVLLQSYRWLVEPLDRDFDERVRMFETGTLVNMCHNIFNCSITCPKFLNPGLASKEIKRLSSPAAKRVGPAIE..........  
s2:
................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILR..IGGETHAHAHRMALKILDDMNLMRV.PYSAATTEILQAVAFNDG....PFDNSPLLFEMIE...YPERGEVHVLIRSPDTHPNLQR  
s1:
.......................................EDHRKYKVQREELPRMPHFNDFNDPRFCGTTNKQKNGILAYYQWLHCIGNWGEEHSMCKKMRWYVERMMHETWLEKWEEKRALGHFDHTILYGVKPWKEFEPLYQPVKKNRKGAYEYWLDR.DFEPLYDADAADWREKAPILHDMFVLGKKPVA  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILR.......IG..GETHAHAHRMALKILDDMNLM...RVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR........................  
s1:
...............................................WPSKLPLTKNWYYHLSRRD....SIADETRQYMVVGDFLLLFVVSFSMYRLYVLNRNNTYQTHLSHLINYPPAIIANEFDFKDSNANRLVERKDLDAYREDVVRCRAS........  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPG..VRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFD....NSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
................YGHALELDTHNYKFNGEPPSWMKTHAKTEEETSFAKSVLPHIDFASSYECLLFDADRLNTNLNRKEFGNEIKYRLEKQANTVARAQQLLKDKKAGTGPDAAKIENTLIARIFDEEHVQAEMKYVKCIRANELAEDNRLDILPGGSPNSLREKTRWNLNTELHPADRAEIGARLTAWLPEKYHIVYFDDFQTVAANDATARREMLEIVESVQKEYTAEAKEGGYESDLKETVAELMDDVDPTRAITMEAIKSCKDLQQLEDWSRQVHEYNGDDRIIEIYARAAEITKNAEHQALVKQMREWRKLATK  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRF...APLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGET......HAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR............................................................................................................................................................  
s1:
...................................................................................................SLSTILYSPIGTSMMIMLAYNVIVICSKHVNYSLEITAKDYVQDQQLLTIMRYGILSCILLGMEVMFIEIG  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFN....DGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........  
s1:
..............PRPFGVWA...PATTLAEYRARIPNPFAYSFKWVYSMKREVFYPPEALAHFKDPQQFKDAVDTVIAMRVSDKIFGEGQKLP...RHPVILMLMVLATHGFIIFSGLKYYYGTYMPANNPTWRKTV...NKEWEEAINNSPWDHMSHVWQYSDEYAAALGDTAAPGQRKFYIPA  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPT...PGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPF..DNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........................  
s1:
.........................PATVKRPLWSLLLPQTYTSRIHTLAFHAPSILFMIAVCAIISKQSYYRSSLADE......DPKTYDRIDRRAYVALPDGRMALVYPIIDTQTSFTRTVISFLDAVNPF.................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTS.IEQQVAKRFS....KDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRV.P.YSAATTEILQAVAFND..GPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
IYTTWGSVPCEDWARNESWLKRITSQSDYRSFEFWHVPQADVPAGLRLNAVERYLLSSLENDTDRLLHVSWCEDFDPYWHDRVGSLEMLYKIVYTNDYPLYRYIFGNCMHKVAEKEYMLRKLNYLKSVLFWAGRTERCYTSIVKARYYVQRCVWNALERERYLCACVEAVDSFGKKVPEELRQKVMPELEVALVSMRHWVWDCPNGKRTFTRRLA...................................................................................................................  
s2:
.............................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
......SLADKIVRGPPKSVYYTHPRYVMSRDKMLHTIWVDIGIFQTCAYALFPFFSAAYFFK.....................................................................................................  
s2:
VNKVPASLLEKVCN..PRLVAFTAMDLARTRFAPLYT.....SIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..............TYMLAFNSKAKARPNFGLRGVGYWTSEVYHKPGQNYWMVVCCAGPFLLVGAIMMDGF.WSKLDDIAG....GGPSALDYGWRSQDRKPWDFSFDIGEGYAAGPAVYRPASGAVDL...................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRF....APLYTS.IEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGG.ETHAHAHRMALKILDDMNL.MRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
KAVLQLVRFDPETNSSRVESYEYDKHHEYMVLDLLIAVKAHQDPTLAFRSSCCEGVCGSCAMNINGINSLACITFAQHVTTVAPLPNFPVIKDFVVDLR.HFFQQYAYIRPYVRNANLHRSQVDGIVERYNTVARVLSGVSPSEGRAMEKAQEELRETTVAALLRIADAAVDAGNATQALSVLEKVEQQGVVLDSTRVTEMIERALKNFAAKS................................  
s2:
.................................................................................VNKVP..ASLLEKVCNPRLVAFTAMDLAR..TRFAPLYTSIEQQVAKRFSKDPSKLQP.TPGVRTAVKDAFDTSVCNDIANILRIG.GETHAHAHRMALKILDDMNLMRVPY.SAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
....YETFTPKTLSGRLVMPGNINL..LTVSPLYCAVLCIAAATWGVFYWDIYCRKNYETVLIARPKDM............................................................................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRT....AVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
MFVRVIFVGVSGVFVFLSLPAICIVYLTFCLCGLFCIMFGSFIFIDYCFICFFACLLFCLVCLLCDLFVDSLRGLFDVCCFIRCIQYCFVWFIISELLLFLSLFYVVFSLVLFVSVEFAFVFVIPVMFSCLICDFGFVFYWYFIDIFNLLINTFLLFVSGLFVNFVLFLFWFRFFLCVLFMLWVGILFGFLFLWNQVWEFALLFVTCSCGVFGSILFLIDLLHFSHVFLGIFLLFLCFSRCFNFLCMD...TRFVFLYVVCLYWHFVDCVWFFLLRFVYFDVLSVV........................................................................................................  
s2:
................................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLY........TSIEQQVAKRFSK.DPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
MFLGGFVPRRFTQLNRDPWWMFFIFSVGAWIGEYPAMQIKYNARDLVLDPHRYVWSHLDDHH..................................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
MGHEETTFSRGNRTRNNALQHIYGLMGLCGVGCVLALFSFVSGQRRIQTTITADGTMTKGTC.PT......................................................................................................  
s2:
..........VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
MAFILSFWMIFLLDSVIVLLSFVCFVCVWICALLFSTVLLVSKLNNIYCTWDFTASKFIDVYWFTIGGMFSLGLLLRLCLLLYFGHLNFVSFDLCKVVGFQWYWVYFIFGETTIFSNLILESDYMIGDLRLLQCNHVLTLLSLVIYKLWLSAVDVIHSFAISSLGVKVDCIPGRCNEIVLFSSNNATVYGQCSELCGVLHGFMPIVICFI.......................................................................................................................  
s2:
.......................................................................................................................................................................VNKVPASLLEKV...CNPRLVAFTAMDLARTR..FAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
YTRWKCDRIPVLQLKLFTQEYNIMALVGLLSMVFLFKHASYCSEETERKNGWWAGYPYWRDPIARRNEIRYKQLINSNDVDITDPKWTG..CSKEQ......................................................................................................................  
s2:
.........................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..............TYMLAFNSKAKARPNFGLRGVGYWTSEVYHKPGQNYWMVVCCAGPFLLVGAIMMDGF.WSKLDDIAG....GGPSALDYGWRSQDRKPWDFSFDIGEGYAAGPAVYRPASGAVDL...................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRF....APLYTS.IEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGG.ETHAHAHRMALKILDDMNL.MRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
.................................................................................................TMNFGNMTLGGA....MATFGGQSNPMCNYTSPLAKKFV.YKEVGKVHYPLRRHVFRTKVRTAAEIRFNEIVKRYMKEKMTFKRGCYAATITNTVELDHMGSIIPKDEYEVKRLTSYMTSKKMSSDYKKHMQELWTRVLFVCESTNLVGVTENAMHQNSRPGTDEEFMSIIWYSSFVTTLMAFVVTLFIWWYRYGQAPQYAEF  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDN..SPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.............................................................................................................................................  
s1:
................YGHALELDTHNYKFNGEPPSWMKTHAKTEEETSFAKSVLPHIDFASSYECLLFDADRLNTNLNRKEFGNEIKYRLEKQANTVARAQQLLKDKKAGTGPDAAKIENTLIARIFDEEHVQAEMKYVKCIRANELAEDNRLDILPGGSPNSLREKTRWNLNTELHPADRAEIGARLTAWLPEKYHIVYFDDFQTVAANDATARREMLEIVESVQKEYTAEAKEGGYESDLKETVAELMDDVDPTRAITMEAIKSCKDLQQLEDWSRQVHEYNGDDRIIEIYARAAEITKNAEHQALVKQMREWRKLATK  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRF...APLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGET......HAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR............................................................................................................................................................  
s1:
FFGKGWDNAALDTIFSSMLRKPEVNDRIRTQYASTMDPRDADVLRRLGEVSKENKTFIRVFLPPHLGDPHRLLKCYSLMAYPILDDKGGQLKVEMDGCKLDAFADPDDDYSKVVIPHIELVEYLAKSLLETMKWEATPRGAASLLESLYRGAEIPDHVFQTPAVIERLEDYKDGNKVIS.......................................................................................................  
s2:
........................................................................................................................VNKVPASLLEKV...CNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFS..KDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
.....................................................................................LHFPLSPPPIEIDY.LDSDPLEFAVRTEARRWGFDDLQYMRELAFVRIKENPSIGDFRRM..TPEERRDLFWGSDRQDFFRYITLKLTGHPEHLYHRGW  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR...........................  
s1:
...........................TPYQDKSYPVQPHNLDELQQPPDSWRKSPIMSKLMDQSL..PVYDDV..VTGVGRLYWQEPARVWHLFEADDTLMLEEHDREEWNDRPYVAVNHLYEPPIGSEERPIRVEGTGNP..GDQQIVLCFGNCAPHVPQSNYYMMMKGYNKTKCPMCQQWFYIHNRPWLVMHPDWTDEPAADEGPAYTFSEIEAEFDRDFHEFGVYLNAE  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFN...DGPF..DNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.......................................................................  
s1:
MFWLCLVCLSVSHKMIGLCYLLVAILSGFVGYVYSLFIRLELSLIGCGILFGDYQFYNVLITSHGLIMVFAFIMPVMMGGLVNYFIPVMAGFPDMVFPRLNNMSFWMYLAGFGCVVNGFLTEEGMGVGWTLYPTLICIDFHSSLACDFVMFAVHLLGISSILNSINLLGTLFCCRRKFFSFLSWSLFIWAALITAILLIITLPVLAGGVTLILCDRNFNTSFYDVVG.....GGDLILFQHIFWFFGHPEVYIILLPVFGLISTIVEVIGFR.CVFSTVAMIYSMILIAILGMFVWAHHMFVVGMDVDSRAYFGGVSILIGLPTCVKLFNWIYSFLYTDMIITFEVYFVIMFIFMFLIGAVTGLFLSNVGIDIMLHDTYFVVGHFHYVLSLGAVVGFFTGFIHFLAKWLPIELYLFWMFYFISTLFIGSNMLFFPMHSLGMYAFPRRISDYPVSFLFWSSFMLYGMLLLASLILFLCALFCVFLFWDYCLFFVSLFVFSLYCFFYFSTWLPCVMVLYLLLVDFAHIVLDYLFLILCFCFVFFIFFWQSLFLFFYI  
s2:
.....................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPT..PGVRTAVKDA.FDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEV....HVLIRSPDTHPNLQR..................................................................................................................................................................................................................................................  
s1:
MFVRVIFVGVSGVFVFLSLPAICIVYLTFCLCGLFCIMFGSFIFIDYCFICFFACLLFCLVCLLCDLFVDSLRGLFDVCCFIRCIQYCFVWFIISELLLFLSLFYVVFSLVLFVSVEFAFVFVIPVMFSCLICDFGFVFYWYFIDIFNLLINTFLLFVSGLFVNFVLFLFWFRFFLCVLFMLWVGILFGFLFLWNQVWEFALLFVTCSCGVFGSILFLIDLLHFSHVFLGIFLLFLCFSRCFNFLCMD...TRFVFLYVVCLYWHFVDCVWFFLLRFVYFDVLSVV........................................................................................................  
s2:
................................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLY........TSIEQQVAKRFSK.DPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..................................................................................................................................VAKISSIERASTYLRFSTLRVHPHHEPNFRARPVGWKAWNSKQYMDPWAPYPLTSPVRHVDRPFSGMWFGMGHFALKNFFGPLNWKFWARVSFFGTLGWAYSLSSYALRMHRNGWEWKNRGAVF  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.................................................................................................  
s1:
..........................................................DMHSSDRFKAA.WDEIP..LHMLGASHKQMFEWYWRAMYQLGL.RDPYRLT...KLRSMLNWAALFSFMYLTYISIFYSSFYHVYMM....DWPEHFKRENAREYALSHGHDVWAGDGKFIRPYFHINPPMLTMTSEDI  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR........................................  
s1:
MAFILSFWMIFLLDSVIVLLSFVCFVCVWICALLFSTVLLVSKLNNIYCTWDFTASKFIDVYWFTIGGMFSLGLLLRLCLLLYFGHLNFVSFDLCKVVGFQWYWVYFIFGETTIFSNLILESDYMIGDLRLLQCNHVLTLLSLVIYKLWLSAVDVIHSFAISSLGVKVDCIPGRCNEIVLFSSNNATVYGQCSELCGVLHGFMPIVICFI.......................................................................................................................  
s2:
.......................................................................................................................................................................VNKVPASLLEKV...CNPRLVAFTAMDLARTR..FAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
SRVSNKISGGMACQTVVNHGYYLKPMTGNPYLCTQHDGVTTAYQQGFAPKDFNWLYRFRYNLLPQGMSGGFFSRNPYGRYVHWLEVSTIEKMRLQMFTMESVPCSVVSLILLVFTMWHSYRLAFLHPDITLYNLG.LWSTKPWVQQQRFNKKKELDQDVYRWMTRVPEVMMDDPIREMYK.MGITANDPVYAMAKEQGVEHELTMTHAEYTSTSPDIRRVIANARK...................................  
s2:
..................................................................................................VNKVPASLLEKVC......NPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..........................................................................TYFYANCGETGISGATMQVLLKLTLACCVVQVFAIRYFVFQRLTTKKQFVEDSTDLWESDGTEMDGEEAVANLRIQHERIMPFMNDIKDKLDAQ  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGE...VHVLIRSPDTHPNLQR........  
s1:
.....................YTELSHMKF.PVYYGAVGVVLGYFVVMWVVFLRMGSKHTA.RSEFKNDYLRVWRRRLGTGYEWADAWGPEMGTFFKDLPEE........................................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGE.THAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
.......................................EDHRKYKVQREELPRMPHFNDFNDPRFCGTTNKQKNGILAYYQWLHCIGNWGEEHSMCKKMRWYVERMMHETWLEKWEEKRALGHFDHTILYGVKPWKEFEPLYQPVKKNRKGAYEYWLDR.DFEPLYDADAADWREKAPILHDMFVLGKKPVA  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILR.......IG..GETHAHAHRMALKILDDMNLM...RVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR........................  
s1:
.....................................................................................ASCRTGRLPMPDD......PLFNSTHMHGLRHSSRIAGLGMIAVIWIMYEKLRHSHHYITYKGPENPFARIRHRRFPGGAFMFGWGNNGLNRDCGIKEFECWAGYTGKEYTYV  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........................................  
s1:
..............PRPFGVWA...PATTLAEYRARIPNPFAYSFKWVYSMKREVFYPPEALAHFKDPQQFKDAVDTVIAMRVSDKIFGEGQKLP...RHPVILMLMVLATHGFIIFSGLKYYYGTYMPANNPTWRKTVNKEWEEAIN...NSPWDHMSHVWQYSDEYAAALGDTAAPGQRKFYIPA  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPT...PGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPF..DNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........................  
s1:
MLRRHAYKTAACVTAIQVARAVHSIAVLQNSTPATTAQKLGSVVSKEEVAAVNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLIATITDEVDYTSIEQQVAKRFSKDPSKLQPTPGALKHFRENNWKDMKSLITFYEETMYPIRMKHKEYKYHELTSFHIKDVLKRGLSAFKQSYLDEQREEQTKVKAYMKSCDDFVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVGTASLENISDEVLKLISNRHQTPLDDGVLIRSPDTHPNLQRSPE  
s2:
...................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPL.........YTSIEQQVAKRFSKDPSKLQPTPG................................................................................VRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVH............................VLIRSPDTHPNLQR...  

> matchmaker #6/L3 to #1.2/L3

Computing secondary structure  
Parameters  
---  
Chain pairing | bb  
Alignment algorithm | Needleman-Wunsch  
Similarity matrix | BLOSUM-62  
SS fraction | 0.3  
Gap open (HH/SS/other) | 18/18/6  
Gap extend | 1  
SS matrix |  |  | H | S | O  
---|---|---|---  
H | 6 | -9 | -6  
S |  | 6 | -6  
O |  |  | 4  
Iteration cutoff | 2  
  
Matchmaker copy of combination, chain L3 (#1.2) with chainL3.cif, chain L3
(#6), sequence alignment score = 562.7  
RMSD between 77 pruned atom pairs is 1.065 angstroms; (across all 157 pairs:
26.079)  
  
Computing secondary structure  
s1:
ASKEEQIKKNTKIAIEMIRRYKGETPMSYTRKHTATIEQLEREIEALLGGAQKMRKATTDDQPMDKLGLMERCLRHALWSYHKDEGKYDFDEIARWVVYTPEDEVKLAQMKRQVEAKSKLAAYRAKRAEQGLPEAPVPQISWEEEYKNVTDRELVNEKRLRYDTIAANTMERDEAQIEAVLQQYRKPIQDKRLDDLVDLLERFKPVLAREAIMQRLTIKHLEGQLGVWRYMDWCPEVRDRAELEVDISGFQWWSPLEERRLLPVRLRSVNEVREIMAQTQSSKAAEASAHSPQASQSAGDGDRERLLKEVLALQARIHQRDDAP  
s2:
.............................VNKVPASL..LEKVCNPRLVAFTAMDLARTRFAP.....LYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVL..IRSPDTHPNLQR.................................................................................................................................  
s1:
PAEHKGRVGYVSQVIGAVVDVHFSEGVPPVLTALDVTEDLGRDEPLTLEIVQHLDANTGRCIAMQTTDLLKLKSKVVSTGGNISVPVGRETLGRIFNVLGDAIDQRGPVGEKMRMAIHAEAPKLADQAAEDTILTTGIKVIDLILPYCKGGKIGLFGGAGVGKTVIIMELINNVAKGHGGFSVFAGVGERTREGTDLYLEMMQSKVIDLKGDSKCVLVYGQMNEPPGARARVAQSALTMAEYFRDVEGQNVLLFIDNIFRFTQANSEVSALLGRIPAAVGYQPTLAEDLGMLQERITSTTKGSITSVQAVYVPADDITDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMDPDVIDVNHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQVAEVFTGMTGHYVQLNDTVESFSGLLMGSYDQIPEMAFYMVGGINSVLEKAKAMAEEAAAMEK  
s2:
....................................................................................................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQP..TP...GVRTAVKDAFDT...SVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........................  
s1:
FFGKGWDNAALDTIFSSMLRKPEVNDRIRTQYASTMDPRDADVLRRLGEVSKENKTFIRVFLPPHLGDPHRLLKCYSLMAYPILDDKGGQLKVEMDGCKLDAFADPDDDYSKVVIPHIELVEYLAKSLLETMKWEATPRGAASLLESLYRGAEIPDHVFQTPAVIERLEDYKDGNKVIS.......................................................................................................  
s2:
........................................................................................................................VNKVPASLLEKV...CNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFS..KDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
KATEMIGYVHSIDGTIATLIPAPGNPGVAYNTIIMIQVSPTTFAAGLVFNLEKDGRIGIILMDNITEVQSGQKVMATGKLLYIPVGAGVLGKVVNPLGHEVPVGLQTLGKVDAGAPNIVSRSPVNYNLLTGFKAVDTMIPIGRGQRELIVGDRQTGKTSIAVSTIINQVRNNQQI......LSKNAVISIYVSIGQR.CSNVARIHRLLRSYGALRYTTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNVAMKAVAGKLKGILAEYRKLAADQVQTVPMIRGARFVALFNQKNPSFFMNALVSLYACLNGYLDDVKVNYAKLYEYLLVNKDLSVMYGTATNKFFYMYVQQLNYVIRFFTLNHPILNAEVEEMLKQHTHLFLQHYQSKMNAIKTEKEIKALKNLLYSCKRAV  
s2:
.............................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVR.TAVKDA..FDTSVCNDIANILRIG.GETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIE.....YPERGEVHV.LIRSPDTHPNLQR...............................................................................................................................................................................................................  
s1:
EHKGRVGYVSQVIGAVVDVHFSEGVPPVLTALDVTEDLGRDEPLTLEIVQHLDANTGRCIAMQTTDLLKLKSKVVSTGGNISVPVGRETLGRIFNVLGDAIDQRGPVGEKMRMAIHAEAPKLADQAAEDTILTTGIKVIDLILPYCKGGKIGLFGGAGVGKTVIIMELINNVAKGHGGFSVFAGVGERTREGTDLYLEMMQSKVIDLKGDSKCVLVYGQMNEPPGARARVAQSALTMAEYFRDVEGQN...VLLFIDN..IFRFTQANSEVSALLG.RIPAAVGYQPTLAEDLGMLQERITSTTKGSITSVQAVYVTDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMDPDVIDVNHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQVAEVFTGMTGHYVQLNDTVESFSGLLMGSYDQIPEMAFYMVGGINSVLEKAKAMAEEAAAMEKQRRAR  
s2:
...........................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANIL.RIGGET.HAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFND.GPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR...........................................................................................................  
s1:
KGRVGYVSQVIGAVVDVHFSEGVPPVLTALDVTEDLGRDEPLTLEIVQHLDANTGRCIAMQTTDLLKLKSKVVSTGGNISVPVGRETLGRIFNVLGDAIDQRGPVGEKMRMAIHAEAPKLADQAAEDTILTTGIKVIDLILPYCKGGKIGLFGGAGVGKTVIIMELINNVAKGHGGFSVFAGVGERTREGTDLYLEMMQSKVIDLKGDSKCVLVYGQMNEPPGARARVAQSALTMAEYFRDVEGQNVLLFIDNIFRFTQANSEVSALLGRIPAAVGYQPTLAEDLGMLQERITSTTKGSITSVQAVYVPADDITDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMDPDVIDVNHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQVAEVFTGMTGHYVQLNDTVESFSGLLMGSYDQIPEMAFYMVGGINSVLEKAKAMAEEAAAMEENKAAH  
s2:
................................................................................................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQP..TP...GVRTAVKDAFDT...SVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR..............................  
s1:
.............................................................KYDLFGYEV..DTNTAPWIEKVKKCRYYDEAGEVLVSMNVKNCPPDLETYNATLQKIFEAPSKQEKPVENESKFCAMMDLMEEMQHRNKVK.....PNEESWTWVMKECVQSGQFRLGYCVAKLMEAEFKRVPEDLVKQNEANAAKAKADGKEHPSTLAQQQSLFDIKIQ  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVP.....YSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.....................................................................  
s1:
.....................................................................................LHFPLSPPPIEIDY.LDSDPLEFAVRTEARRWGFDDLQYMRELAFVRIKENPSIGDFRRM..TPEERRDLFWGSDRQDFFRYITLKLTGHPEHLYHRGW  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR...........................  
s1:
ASDLKMVSLHKILIGEVQFRNNALLKACNIEHNFGPTWKSEIEAYAKSLPAEEKNCLERQIARVSMTRYTTRELAEYCGEGPEHVDAVAREANIAQAKVYAQKNGADKLETYVKAEAKNA....GWSEAETK....KFMDAVKAAK......................................................  
s2:
.........................................VNKVPASL..LEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
...........................................................AKKYDLFGYEVDTNTAP..WIEKVKKCRYYDEAGEVLVSMNVKNCPPDLETYNATLQKIFEAPSKQEKPVENESKFCAMMDLMEEMQHRNKVK.....PNEESWTWVMKECVQSGQFRLGYCVAKLMEAEFKRVPEDLVKQNEANAAKAKADGKEHPSTLAQQQSLFDIKIQ  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVP.....YSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.....................................................................  
s1:
TEMIGYVHSIDGTIATLIPAPGNPGVAYNTIIMIQVSPTTFAAGLVFNLEKDGRIGIILMDNITEVQSGQKVMATGKLLYIPVGAGVLGKVVNPLGHEVPVGQTLGKVDAGAPNIVSRSPVNYNLLTGFKAVDTMIPIGRGQRELIVGDRQTGKTSIAVSTIINQVRNNQQI......LSKNAVISIYVSIGQR.CSNVARIHRLLRSYGALRYTTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNVAMKAVAGKLKGILAEYRKLAADVQTVPMIRGARFVALFNQKNPSFFMNALVSLYACLNGYLDDVKVNYAKLYEYLLVNKDLSVMYGTATNKFFYMYVQQLNYVIRFFTLNHPILNAEVEEMLKQHTHLFLQHYQSKMNAIKTEKEIKALKNLLYSCKRAV  
s2:
..........................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVR.TAVKDA..FDTSVCNDIANILRIG.GETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIE.....YPERGEVHV.LIRSPDTHPNLQR..............................................................................................................................................................................................................  
s1:
........................................................GAKK..YDLFGYEV..DTNTAPWIEKVKKCRYYDEAGEVLVSMNVKNCPPDLETYNATLQKIFEAPSKQEKPVENESKFCAMMDLMEEMQHRNKVK.....PNEESWTWVMKECVQSGQFRLGYCVAKLMEAEFKRVPEDLVKQNEANAAKAKADGKEHPSTLAQQQSLFDIKIQ  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVP.....YSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.....................................................................  
s1:
SIAVIAAGAPAALLQAVSSILSKATGGAVKATQATSAA.SNAVVVGMQAPRGVYACVAEPPSTASGPYAGVKTVVVRAILPRSAPDTMQVRDILDVYPASGIACEKETAEAVKNFTKAAKVAVEKAKAMKATRVTLVMKPATKYERLNGLFRETCTKTIEAAGLSVETSTTAAATNTLIMFPEK..MSVVMVSDDPVCENVQYAYAGAVGGVHTTYYTDSGNKIYGGHSYRSVAMALAEELKSLGMKAEAAKVEAAVQKSPRNAAAAM  
s2:
............VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQ.PTPGVRTAVKDAF......DTSVCNDIANILRIGG.....ET......HAHAHRMALKILDDMNLMRVP...............YSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPD.THPNLQR.................................................................  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
..................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
SIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
..................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
..................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQP.NLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS..........................................................................................................................  
s2:
..................................VNKVPASLLEKVCNPRLVAFTAMDLAR.....TRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..........YTPSEELKKLYASDFERAQFP...ANIVPSDSVTFAKFLYKAVEPKGSFDAILKDFQTIAAAIPK..LPIFWERTV........VVSEVNEFK.SLSAPTIFTLEWMQSN.GMLDLLPDVAEVYETYVSAKMKRVTAKIYVAPGKEQDRALVDKARKVAEQVVKDNKQLAGYTLVPKVLVDRSIVEGFAVDVQGTYVNEAVGRKIETEVLRKYLDSLSLYDAEELKSGV  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR..................................................................................  
s1:
VALNWRDHGISYVKYLNVATEALHMATKDKARAKYSRFSTPNYIALVKKVPAFT.....................................................................................................................................................  
s2:
..............................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
FFKATEMIGYVHSIDGTIATLIPAPGNPGVAYNTIIMIQVSPTTFAAGLVFNLEKDGRIGIILMDNITEVQSGQKVMATGKLLYIPVGAGVLGKVVNPLGHEVPVGLQTLGKVDAGAPNIVSRSPVNYNLLTGFKAVDTMIPIGRGQRELIVGDRQTGKTSIAVSTIINQVRNNQQI......LSKNAVISIYVSIGQR.CSNVARIHRLLRSYGALRYTTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNVAMKAVAGKLKGILAEYRKLAAQTVPMIRGARFVALFNQKNPSFFMNALVSLYACLNGYLDDVKVNYAKLYEYLLVNKDLSVMYGTATNKFFYMYVQQLNYVIRFFTLNHPILNAEVEEMLKQHTHLFLQHYQSKMNAIKTEKEIKALKNLLYSCKRAVG  
s2:
...............................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVR.TAVKDA..FDTSVCNDIANILRIG.GETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIE.....YPERGEVHV.LIRSPDTHPNLQR.............................................................................................................................................................................................................  
s1:
LSLLLCVHFSAIHR..PPPPVPFTALA......AFLYALTLTAPVAEQRS..GSSLHPQIEVGTEIEDMALFHLVVLPLVFFAAMCIGRG.........................................................................  
s2:
...VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYT.SIEQQVAKRFSKDPSKLQPTPGVRTAVKD..AFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
QMKVELTMQYLDEWMLRWRKFQTESDWQIEKNRQWWRKANIVTAGAVMGGLVMYTAGNATIRRQFGAPHFFDIGVDGKLKEAICDTMTSRWRYTPQGYGRVMLVGLPTFFVFAISEHIQERRRLRAYVRQNTVFGEQARRLVQNGKIEEYLAVDIKASLP.QNQTQLYAG....................................................................  
s2:
.......................................................................VNKVPASLLEKVCN..PRLVAFTAMDLARTRFAPLYT....SIEQQVAKRFSKDPSKLQPT...PGVRTAVKDA.FDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
.............................................................................................................................................NMFLFKDPVRRPQLSPEERAKVKINYAEWPEEFRDYDPDDPYKNSPEIIEGLSSWNLFLWGVECAFIYQFYEVVFPKS  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR..............................................................  
s1:
....................NPVDHFRPNLKFLSVYVEHQYVVDKWLHVKENWLKPWYLPWW.TPMYQAM.TWYSQRNRNLMLVENHLNYRPYRYRRNDEDREN....PY...................................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLAR..TRFAPLYTSIEQQVAKRFSKDPSKLQP..TPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
VFFSTYRSKRIVAPGFLKGPVMASRAFFDYYFQRAWCGCVQWVIPGEVRLWACGVPVIYFIHRYHNDHSLEPDFVEKAMIQRWGG..SLEEVR.KLSPQDQLRIRAFTDLEKLYSAYGPKD.TIVQP.PGDLLPGKDYYH..........................................................................................  
s2:
..................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAP.......LYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
GTWSVLKKNCLNFVPGLALFASQSRDAFATWMKIYNRGYKYGPQEFSDQAEAYTPDYWKRGHSQEKNMWVDMKLSEEVSQKELAQLMHYKQDLWRMGHGLGLSLFLGGYALIPAFFCLSSDTFAPSCFCKTEEEKKAWREAQDMYRYRSAPSYIMDTKWHFD.FHAYPWN....ATQERAWDDLFEKNNVRRDPKVLRPAAEMYDGFLKFYQIRRKSLRHLARSMNLPTFPLLSRTCASTRVKDYWNLAWNEDYMVITQKLHHQMSDEDLHDYAWRRFLAPYDKNLSRDEIMTRVNDYHEFLGPKFVEEGKAPNMIILTNYVLGYYNDPAYLVEDISALDGNDFEYMAHYGKDAFLRRLEFENGPLRDQVEAHTQKLIADRAAAAAAEA  
s2:
.......................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.................................................................................................................  
s1:
HLEPMSVWYLSSWTCVWWYSFFFWLPVLWADMIVPSFVYNKLPVIHFIQEKRAEQKLRRVLDETYTQ................................................................................................................................  
s2:
......................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
...............................................HPPKLEDIP.PSSATKGFFGAYMARLIDIKWMMNRSVELGREYYISAPTLYLFLWMFCWKGFVIMRYGDGKPP.............................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCN..DIANIL....RIGGE..THAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
................................................................................................................VGNGPTFHTAGDNNNTSEIQNAFPINERG...IRSSSPFPEPNTAIYDSYMPWTYFQPIDVKVDKMPAPEAKYYQHHTKKPWDVSTTDLIEIQSRKKYVQGVGYFLMMIYLYFLMPKEKSYSGTTGSDGFYVMLPKNQPEKFV  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFND.GPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.................................................................................................  
s1:
MFVFFVCDLVIMRILLCFCYSVWSRIIFVLFYNVFYICTELMFCIFDVYLFVGLCMFICLWFVLFNFYGLIVYYCITYLNVYILFCIVFMYYMAFLFCFCFLLDFILFGSLLVGDAFMDVFFLRYLLCVLECFSLLCRCISTFLRMFCNLLSSHFLMLMFCDFVYFFIIFFLFFIMCDFIYFIIFTFAMLFCIIFYLFLYALDMFCALLQIFIFCNMIMQLIMDFLL...LLSFHG.......................................................................................................................................  
s2:
......................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
FTVPVALCTKQVAAMDEPLKRHIDAYEARGEDVTIAVWREYVDGQRALLPYRWAKFRNEVTYLTSGQIALTDLAFADLLLFVRFLTKCLFIFIVAVMAGRRSVFPS.LEPTSPFVEEIVKN.WQPNRLRRVAGAEYMARDQAAAAAAAAA................................................................  
s2:
........................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPT.PGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
........................................................................................................PKTLNQFRNFSYIVVAWLGFNKGFREKAANDAEWIAHQQRVRQQNVERHQAASAMMEA  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVP.....YSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..........................................................................................VAPKTLN.......QFRNFSYIVVAWLGFNKGFREKAANDAEWIAHQQRVRQQNV............  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
AFHDVSTDAIRQMQASEALQKHLENAQLAHRVCVAKALKADEPPVEK.CALTWGEVVMRYNQWSEYRPAFHDSDAQ..KRYSKYWTKKRQA......................................................................................................  
s2:
....................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
SRVSNKISGGMACQTVVNHGYYLKPMTGNPYLCTQHDGVTTAYQQGFAPKDFNWLYRFRYNLLPQGMSGGFFSRNPYGRYVHWLEVSTIEKMRLQMFTMESVPCSVVSLILLVFTMWHSYRLAFLHPDITLYNLG.LWSTKPWVQQQRFNKKKELDQDVYRWMTRVPEVMMDDPIREMYKM.GITANDPVYAMAKEQGVEHELTMTHAEYTSTSPDIRRVIANARK...................................  
s2:
..................................................................................................VNKVPASLLEKVC......NPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..................KLYASDFERAQFPANIVPSDSVTFAKFLYKA...VEP........KGSFD.AILKDFQTIAAAIPKLPIFWERTV..VVSEVNEFK.SLSAPTIFTLEWMQSN.GMLDLLPDVAEVYETYVSAKMKRVTAKIYVAPGKEQDRALVDKARKVAEQVVKDNKQLAGYTLVPKVLVDRSIVEGFAVDVVNEAVG  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRF.APLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR...................................................  
s1:
SGRLRLYKEKLEGYNRFYSIVKTIKMVTMAKFRQAQVRIKTRDYTL..RYTEKAFSKPGQLVGDSPQAKAIYIPVMTNRGSCGALNSNVVKVIDSVASSRAYLMPLGKRGIESLSKLYPSSFRMGIVNDM.HEPMHFAYATYVWENAQQLCPEADRVHIIFHRCVSAGSQKQCYYNIPAYEKWKEDLVDASSTENQKSRYLFANTLLNEDEQMIRDFYDFHATLAILNAVCENELSEQAARLVAVEGQLSNISTLQQKTSSLYNKTRQSSITSSLIEIISAMTSLEGNAAKGVQRTN  
s2:
.......VNKVPA..SLLEKVCNPRLVAFTAMDLARTRFAPL.YTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAF.DTSVCN.DIANILR.IGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEY..PERGEVHVLIRSPDTHPNLQR.............................................................................................................................  
s1:
.....YTELSHMKFP..VYYGAVGVVLGYFVVMWVVFLRMGSKHTARSEFKNDYLRVWRRRLGTGYEWADAWGPEMGTFFKDLPEE.........................................................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVC..NDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..........................................................DMHSSDRFKAA.WDEIP..LHMLGASHKQMFEWYWRAMYQLGL.RDPYRLT...KLRSMLNWAALFSFMYLTYISIFYSSFYHVYMM....DWPEHFKRENAREYALSHGHDVWAGDGKFIRPYFHINPPMLTMTSEDI  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR........................................  
s1:
..........................................................................TYFYANCGETGISGATMQVLLKLTLACCVVQVFAIRYFVFQRLTTKKQFVEDSTDLWESDGTEMDGEEAVANLRIQHERIMPFMNDIKDKLDAQ  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGE...VHVLIRSPDTHPNLQR........  
s1:
.................................................................................................TMNFGNMTLGGA....MATFGGQSNPMCNYTSPLAKKFV.YKEVGKVHYPLRRHVFRTKVRTAAEIRFNEIVKRYMKEKMTFKRGCYAATITNTVELDHMGSIIPKDEYEVKRLTSYMTSKKMSSDYKKHMQELWTRVLFVCESTNLVGVTENAMHQNSRPGTDEEFMSIIWYSSFVTTLMAFVVTLFIWWYRYGQAPQYAEF  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDN..SPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.............................................................................................................................................  
s1:
............................ELPEAFEFIEHKVTDKDIHSAYENMETLRLTVTRQDEFLFKETPVKCVTIVGVNGENGVYPGHAYEI.TQLTPAPLTVEMP.DGTVKKFFTSGGFAHINNEGSCDINCVECIPLAELDLDAAEKALAQQQSALSSAHDEKAKAVIEIRIGVLESVIQSLKHMKE  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAF...DTSV.CNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAF....NDGPFD.N....SPLLFEMIEYPERGEVHVLIRSPDTHPNLQR......................  
s1:
PLATLKPVLAESVATQNVIRRMIGVTTNRKVNASAINSVAEKTKGEGLAGTTAVVARAHLYLLSRNPTDAVAEIDAVLPKVQDEALRRFAIGIRLRSHNELLDMKEASLGVSGGATESEVSDLRSKLQKDYKELVTSSPGCWLVELAAAEYTLYTGASEEAYKSFSSIEKKIQEYIKAPIHVSELVATADNTNEFSLIGFQVRRARPGVKPEGVSASVAEGMANVMADPAAVKALQQAKKAFEEALELVVTLQEANV....GH...HFHDFFPTTPDHYDKWTSEAARSAQQLIQE.ALTPHSVGLKPEAIDRIRVSMTNKAFYDSEEKLHALLKSAPKDKSIIASIRETFGPGPSTPISSSDQAVADAVESVHLAVVSSDTAGATDYAKRGKEIAKALAKQLLYRTQVQKCVALTEMNCLQEAVDVVTPVIDANEYIYMWRAFLARSRAYKGLGLITNADKDLKELNRLKHSLTERTPYEKK  
s2:
..............................................................................................................................................................................VNKVPASLLEKVC...NPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSK...DPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIE........YPERGEVHVLIRSPDTHPNLQR..........................................................................................................................................  
s1:
MFWLCLVCLSVSHKMIGLCYLLVAILSGFVGYVYSLFIRLELSLIGCGILFGDYQFYNVLITSHGLIMVFAFIMPVMMGGLVNYFIPVMAGFPDMVFPRLNNMSFWMYLAGFGCVVNGFLTEEGMGVGWTLYPTLICIDFHSSLACDFVMFAVHLLGISSILNSINLLGTLFCCRRKFFSFLSWSLFIWAALITAILLIITLPVLAGGVTLILCDRNFNTSFYDVVG.....GGDLILFQHIFWFFGHPEVYIILLPVFGLISTIVEVIGFR.CVFSTVAMIYSMILIAILGMFVWAHHMFVVGMDVDSRAYFGGVSILIGLPTCVKLFNWIYSFLYTDMIITFEVYFVIMFIFMFLIGAVTGLFLSNVGIDIMLHDTYFVVGHFHYVLSLGAVVGFFTGFIHFLAKWLPIELYLFWMFYFISTLFIGSNMLFFPMHSLGMYAFPRRISDYPVSFLFWSSFMLYGMLLLASLILFLCALFCVFLFWDYCLFFVSLFVFSLYCFFYFSTWLPCVMVLYLLLVDFAHIVLDYLFLILCFCFVFFIFFWQSLFLFFYI  
s2:
.....................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPT..PGVRTAVKDA.FDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEV....HVLIRSPDTHPNLQR..................................................................................................................................................................................................................................................  
s1:
.....................................................................................ASCRTGRLPMPDD......PLFNSTHMHGLRHSSRIAGLGMIAVIWIMYEKLRHSHHYITYKGPENPFARIRHRRFPGGAFMFGWGNNGLNRDCGIKEFECWAGYTGKEYTYV  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........................................  
s1:
..................................................................................................................................VAKISSIERASTYLRFSTLRVHPHHEPNFRARPVGWKAWNSKQYMDPWAPYPLTSPVRHVDRPFSGMWFGMGHFALKNFFGPLNWKFWARVSFFGTLGWAYSLSSYALRMHRNGWEWKNRGAVF  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.................................................................................................  
s1:
..............................................................................................................................................KVLIADLPMMWPSDMRRFEKEGGVWGQQFRQRRRQLTFALTISAASTLLGSWYVVMRRRNTYFVLFSTFSGFSVLGFCIGMSLAPLWYENVANNKETSMMRRVWWAKECAKHWD  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRS.PDTHPNLQR..................................................................................................  
s1:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPR.......DGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKE.GRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALY..AEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s2:
.................................................................................................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAP.LYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMR..VPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLI..RSPDTHPNLQR.........................................................  
s1:
...........................TPYQDKSYPVQPHNLDELQQPPDSWRKSP.IMSKLMDQ.SLPVYDDV..VTGVGRLYWQEPARVWHLFEADDTLMLEEHDREEWNDRPYVAVNHLYEPPIGSEERPIRVEGTGNP..GDQQIVLCFGNCAPHVPQSNYYMMMKGYNKTKCPMCQQWFYIHNRPWLVMHPDWTDEPAADEGPAYTFSEIEAEFDRDFHEFGVYLNAE  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFN...DGPF..DNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.......................................................................  
s1:
.............................................................................AEARAVLQAQSHRTVSAVVPGKMFMRHWIVAEQSTVSVVNRVISGMVAVFTMIWAAGYATLGYNGHNSAHVAGWIFIAYWVVLHTHIMWLAPTML  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMR...VPYSAATTEILQAVAFNDGPFDN.SPLLFEMIEYPERGEVHV.....LIRSPDTHPNLQR......  
s1:
PGQLANYSSPLYMYSHLIKNSTAKTPQLYTAKDNSKTAMHLLTRRGATANYTVNRWYLKE.KVDSSNRMRLEGLYECVLCASCTGSCPQYWWNREHFLGPAVLLQSYRWLVEPLDRDFDERVRMFETGTLVNMCHNIFNCSITCPKFLNPGLASKEIKRLSSPAAKRVGPAIE..........  
s2:
................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILR..IGGETHAHAHRMALKILDDMNLMRV.PYSAATTEILQAVAFNDG....PFDNSPLLFEMIE...YPERGEVHVLIRSPDTHPNLQR  
s1:
.......................................EDHRKYKVQREELPRMPHFNDFNDPRFCGTTNKQKNGILAYYQWLHCIGNWGEEHSMCKKMRWYVERMMHETWLEKWEEKRALGHFDHTILYGVKPWKEFEPLYQPVKKNRKGAYEYWLDR.DFEPLYDADAADWREKAPILHDMFVLGKKPVA  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILR.......IG..GETHAHAHRMALKILDDMNLM...RVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR........................  
s1:
...............................................WPSKLPLTKNWYYHLSRRD....SIADETRQYMVVGDFLLLFVVSFSMYRLYVLNRNNTYQTHLSHLINYPPAIIANEFDFKDSNANRLVERKDLDAYREDVVRCRAS........  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPG..VRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFD....NSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
................YGHALELDTHNYKFNGEPPSWMKTHAKTEEETSFAKSVLPHIDFASSYECLLFDADRLNTNLNRKEFGNEIKYRLEKQANTVARAQQLLKDKKAGTGPDAAKIENTLIARIFDEEHVQAEMKYVKCIRANELAEDNRLDILPGGSPNSLREKTRWNLNTELHPADRAEIGARLTAWLPEKYHIVYFDDFQTVAANDATARREMLEIVESVQKEYTAEAKEGGYESDLKETVAELMDDVDPTRAITMEAIKSCKDLQQLEDWSRQVHEYNGDDRIIEIYARAAEITKNAEHQALVKQMREWRKLATK  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRF...APLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGET......HAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR............................................................................................................................................................  
s1:
...................................................................................................SLSTILYSPIGTSMMIMLAYNVIVICSKHVNYSLEITAKDYVQDQQLLTIMRYGILSCILLGMEVMFIEIG  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFN....DGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........  
s1:
..............PRPFGVWA...PATTLAEYRARIPNPFAYSFKWVYSMKREVFYPPEALAHFKDPQQFKDAVDTVIAMRVSDKIFGEGQKLP...RHPVILMLMVLATHGFIIFSGLKYYYGTYMPANNPTWRKTV...NKEWEEAINNSPWDHMSHVWQYSDEYAAALGDTAAPGQRKFYIPA  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPT...PGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPF..DNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........................  
s1:
.........................PATVKRPLWSLLLPQTYTSRIHTLAFHAPSILFMIAVCAIISKQSYYRSSLADE......DPKTYDRIDRRAYVALPDGRMALVYPIIDTQTSFTRTVISFLDAVNPF.................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTS.IEQQVAKRFS....KDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRV.P.YSAATTEILQAVAFND..GPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
IYTTWGSVPCEDWARNESWLKRITSQSDYRSFEFWHVPQADVPAGLRLNAVERYLLSSLENDTDRLLHVSWCEDFDPYWHDRVGSLEMLYKIVYTNDYPLYRYIFGNCMHKVAEKEYMLRKLNYLKSVLFWAGRTERCYTSIVKARYYVQRCVWNALERERYLCACVEAVDSFGKKVPEELRQKVMPELEVALVSMRHWVWDCPNGKRTFTRRLA...................................................................................................................  
s2:
.............................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
......SLADKIVRGPPKSVYYTHPRYVMSRDKMLHTIWVDIGIFQTCAYALFPFFSAAYFFK.....................................................................................................  
s2:
VNKVPASLLEKVCN..PRLVAFTAMDLARTRFAPLYT.....SIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..............TYMLAFNSKAKARPNFGLRGVGYWTSEVYHKPGQNYWMVVCCAGPFLLVGAIMMDGF.WSKLDDIAG....GGPSALDYGWRSQDRKPWDFSFDIGEGYAAGPAVYRPASGAVDL...................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRF....APLYTS.IEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGG.ETHAHAHRMALKILDDMNL.MRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
KAVLQLVRFDPETNSSRVESYEYDKHHEYMVLDLLIAVKAHQDPTLAFRSSCCEGVCGSCAMNINGINSLACITFAQHVTTVAPLPNFPVIKDFVVDLR.HFFQQYAYIRPYVRNANLHRSQVDGIVERYNTVARVLSGVSPSEGRAMEKAQEELRETTVAALLRIADAAVDAGNATQALSVLEKVEQQGVVLDSTRVTEMIERALKNFAAKS................................  
s2:
.................................................................................VNKVP..ASLLEKVCNPRLVAFTAMDLAR..TRFAPLYTSIEQQVAKRFSKDPSKLQP.TPGVRTAVKDAFDTSVCNDIANILRIG.GETHAHAHRMALKILDDMNLMRVPY.SAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
....YETFTPKTLSGRLVMPGNINL..LTVSPLYCAVLCIAAATWGVFYWDIYCRKNYETVLIARPKDM............................................................................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRT....AVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
MFVRVIFVGVSGVFVFLSLPAICIVYLTFCLCGLFCIMFGSFIFIDYCFICFFACLLFCLVCLLCDLFVDSLRGLFDVCCFIRCIQYCFVWFIISELLLFLSLFYVVFSLVLFVSVEFAFVFVIPVMFSCLICDFGFVFYWYFIDIFNLLINTFLLFVSGLFVNFVLFLFWFRFFLCVLFMLWVGILFGFLFLWNQVWEFALLFVTCSCGVFGSILFLIDLLHFSHVFLGIFLLFLCFSRCFNFLCMD...TRFVFLYVVCLYWHFVDCVWFFLLRFVYFDVLSVV........................................................................................................  
s2:
................................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLY........TSIEQQVAKRFSK.DPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
MFLGGFVPRRFTQLNRDPWWMFFIFSVGAWIGEYPAMQIKYNARDLVLDPHRYVWSHLDDHH..................................................................................................................................  
s2:
...................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
MGHEETTFSRGNRTRNNALQHIYGLMGLCGVGCVLALFSFVSGQRRIQTTITADGTMTKGTC.PT......................................................................................................  
s2:
..........VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
MAFILSFWMIFLLDSVIVLLSFVCFVCVWICALLFSTVLLVSKLNNIYCTWDFTASKFIDVYWFTIGGMFSLGLLLRLCLLLYFGHLNFVSFDLCKVVGFQWYWVYFIFGETTIFSNLILESDYMIGDLRLLQCNHVLTLLSLVIYKLWLSAVDVIHSFAISSLGVKVDCIPGRCNEIVLFSSNNATVYGQCSELCGVLHGFMPIVICFI.......................................................................................................................  
s2:
.......................................................................................................................................................................VNKVPASLLEKV...CNPRLVAFTAMDLARTR..FAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
YTRWKCDRIPVLQLKLFTQEYNIMALVGLLSMVFLFKHASYCSEETERKNGWWAGYPYWRDPIARRNEIRYKQLINSNDVDITDPKWTG..CSKEQ......................................................................................................................  
s2:
.........................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..............TYMLAFNSKAKARPNFGLRGVGYWTSEVYHKPGQNYWMVVCCAGPFLLVGAIMMDGF.WSKLDDIAG....GGPSALDYGWRSQDRKPWDFSFDIGEGYAAGPAVYRPASGAVDL...................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRF....APLYTS.IEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGG.ETHAHAHRMALKILDDMNL.MRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
.................................................................................................TMNFGNMTLGGA....MATFGGQSNPMCNYTSPLAKKFV.YKEVGKVHYPLRRHVFRTKVRTAAEIRFNEIVKRYMKEKMTFKRGCYAATITNTVELDHMGSIIPKDEYEVKRLTSYMTSKKMSSDYKKHMQELWTRVLFVCESTNLVGVTENAMHQNSRPGTDEEFMSIIWYSSFVTTLMAFVVTLFIWWYRYGQAPQYAEF  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDN..SPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.............................................................................................................................................  
s1:
................YGHALELDTHNYKFNGEPPSWMKTHAKTEEETSFAKSVLPHIDFASSYECLLFDADRLNTNLNRKEFGNEIKYRLEKQANTVARAQQLLKDKKAGTGPDAAKIENTLIARIFDEEHVQAEMKYVKCIRANELAEDNRLDILPGGSPNSLREKTRWNLNTELHPADRAEIGARLTAWLPEKYHIVYFDDFQTVAANDATARREMLEIVESVQKEYTAEAKEGGYESDLKETVAELMDDVDPTRAITMEAIKSCKDLQQLEDWSRQVHEYNGDDRIIEIYARAAEITKNAEHQALVKQMREWRKLATK  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRF...APLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGET......HAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR............................................................................................................................................................  
s1:
FFGKGWDNAALDTIFSSMLRKPEVNDRIRTQYASTMDPRDADVLRRLGEVSKENKTFIRVFLPPHLGDPHRLLKCYSLMAYPILDDKGGQLKVEMDGCKLDAFADPDDDYSKVVIPHIELVEYLAKSLLETMKWEATPRGAASLLESLYRGAEIPDHVFQTPAVIERLEDYKDGNKVIS.......................................................................................................  
s2:
........................................................................................................................VNKVPASLLEKV...CNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFS..KDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
.....................................................................................LHFPLSPPPIEIDY.LDSDPLEFAVRTEARRWGFDDLQYMRELAFVRIKENPSIGDFRRM..TPEERRDLFWGSDRQDFFRYITLKLTGHPEHLYHRGW  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR...........................  
s1:
...........................TPYQDKSYPVQPHNLDELQQPPDSWRKSPIMSKLMDQSL..PVYDDV..VTGVGRLYWQEPARVWHLFEADDTLMLEEHDREEWNDRPYVAVNHLYEPPIGSEERPIRVEGTGNP..GDQQIVLCFGNCAPHVPQSNYYMMMKGYNKTKCPMCQQWFYIHNRPWLVMHPDWTDEPAADEGPAYTFSEIEAEFDRDFHEFGVYLNAE  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFN...DGPF..DNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.......................................................................  
s1:
MFWLCLVCLSVSHKMIGLCYLLVAILSGFVGYVYSLFIRLELSLIGCGILFGDYQFYNVLITSHGLIMVFAFIMPVMMGGLVNYFIPVMAGFPDMVFPRLNNMSFWMYLAGFGCVVNGFLTEEGMGVGWTLYPTLICIDFHSSLACDFVMFAVHLLGISSILNSINLLGTLFCCRRKFFSFLSWSLFIWAALITAILLIITLPVLAGGVTLILCDRNFNTSFYDVVG.....GGDLILFQHIFWFFGHPEVYIILLPVFGLISTIVEVIGFR.CVFSTVAMIYSMILIAILGMFVWAHHMFVVGMDVDSRAYFGGVSILIGLPTCVKLFNWIYSFLYTDMIITFEVYFVIMFIFMFLIGAVTGLFLSNVGIDIMLHDTYFVVGHFHYVLSLGAVVGFFTGFIHFLAKWLPIELYLFWMFYFISTLFIGSNMLFFPMHSLGMYAFPRRISDYPVSFLFWSSFMLYGMLLLASLILFLCALFCVFLFWDYCLFFVSLFVFSLYCFFYFSTWLPCVMVLYLLLVDFAHIVLDYLFLILCFCFVFFIFFWQSLFLFFYI  
s2:
.....................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPT..PGVRTAVKDA.FDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEV....HVLIRSPDTHPNLQR..................................................................................................................................................................................................................................................  
s1:
MFVRVIFVGVSGVFVFLSLPAICIVYLTFCLCGLFCIMFGSFIFIDYCFICFFACLLFCLVCLLCDLFVDSLRGLFDVCCFIRCIQYCFVWFIISELLLFLSLFYVVFSLVLFVSVEFAFVFVIPVMFSCLICDFGFVFYWYFIDIFNLLINTFLLFVSGLFVNFVLFLFWFRFFLCVLFMLWVGILFGFLFLWNQVWEFALLFVTCSCGVFGSILFLIDLLHFSHVFLGIFLLFLCFSRCFNFLCMD...TRFVFLYVVCLYWHFVDCVWFFLLRFVYFDVLSVV........................................................................................................  
s2:
................................................................................................................................................................................................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLY........TSIEQQVAKRFSK.DPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..................................................................................................................................VAKISSIERASTYLRFSTLRVHPHHEPNFRARPVGWKAWNSKQYMDPWAPYPLTSPVRHVDRPFSGMWFGMGHFALKNFFGPLNWKFWARVSFFGTLGWAYSLSSYALRMHRNGWEWKNRGAVF  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.................................................................................................  
s1:
..........................................................DMHSSDRFKAA.WDEIP..LHMLGASHKQMFEWYWRAMYQLGL.RDPYRLT...KLRSMLNWAALFSFMYLTYISIFYSSFYHVYMM....DWPEHFKRENAREYALSHGHDVWAGDGKFIRPYFHINPPMLTMTSEDI  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR........................................  
s1:
MAFILSFWMIFLLDSVIVLLSFVCFVCVWICALLFSTVLLVSKLNNIYCTWDFTASKFIDVYWFTIGGMFSLGLLLRLCLLLYFGHLNFVSFDLCKVVGFQWYWVYFIFGETTIFSNLILESDYMIGDLRLLQCNHVLTLLSLVIYKLWLSAVDVIHSFAISSLGVKVDCIPGRCNEIVLFSSNNATVYGQCSELCGVLHGFMPIVICFI.......................................................................................................................  
s2:
.......................................................................................................................................................................VNKVPASLLEKV...CNPRLVAFTAMDLARTR..FAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
SRVSNKISGGMACQTVVNHGYYLKPMTGNPYLCTQHDGVTTAYQQGFAPKDFNWLYRFRYNLLPQGMSGGFFSRNPYGRYVHWLEVSTIEKMRLQMFTMESVPCSVVSLILLVFTMWHSYRLAFLHPDITLYNLG.LWSTKPWVQQQRFNKKKELDQDVYRWMTRVPEVMMDDPIREMYK.MGITANDPVYAMAKEQGVEHELTMTHAEYTSTSPDIRRVIANARK...................................  
s2:
..................................................................................................VNKVPASLLEKVC......NPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
..........................................................................TYFYANCGETGISGATMQVLLKLTLACCVVQVFAIRYFVFQRLTTKKQFVEDSTDLWESDGTEMDGEEAVANLRIQHERIMPFMNDIKDKLDAQ  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGE...VHVLIRSPDTHPNLQR........  
s1:
.....................YTELSHMKF.PVYYGAVGVVLGYFVVMWVVFLRMGSKHTA.RSEFKNDYLRVWRRRLGTGYEWADAWGPEMGTFFKDLPEE........................................................  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGE.THAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR  
s1:
.......................................EDHRKYKVQREELPRMPHFNDFNDPRFCGTTNKQKNGILAYYQWLHCIGNWGEEHSMCKKMRWYVERMMHETWLEKWEEKRALGHFDHTILYGVKPWKEFEPLYQPVKKNRKGAYEYWLDR.DFEPLYDADAADWREKAPILHDMFVLGKKPVA  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILR.......IG..GETHAHAHRMALKILDDMNLM...RVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR........................  
s1:
.....................................................................................ASCRTGRLPMPDD......PLFNSTHMHGLRHSSRIAGLGMIAVIWIMYEKLRHSHHYITYKGPENPFARIRHRRFPGGAFMFGWGNNGLNRDCGIKEFECWAGYTGKEYTYV  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPTPGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........................................  
s1:
..............PRPFGVWA...PATTLAEYRARIPNPFAYSFKWVYSMKREVFYPPEALAHFKDPQQFKDAVDTVIAMRVSDKIFGEGQKLP...RHPVILMLMVLATHGFIIFSGLKYYYGTYMPANNPTWRKTVNKEWEEAIN...NSPWDHMSHVWQYSDEYAAALGDTAAPGQRKFYIPA  
s2:
VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLYTSIEQQVAKRFSKDPSKLQPT...PGVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPF..DNSPLLFEMIEYPERGEVHVLIRSPDTHPNLQR.........................  
s1:
MLRRHAYKTAACVTAIQVARAVHSIAVLQNSTPATTAQKLGSVVSKEEVAAVNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLIATITDEVDYTSIEQQVAKRFSKDPSKLQPTPGALKHFRENNWKDMKSLITFYEETMYPIRMKHKEYKYHELTSFHIKDVLKRGLSAFKQSYLDEQREEQTKVKAYMKSCDDFVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVGTASLENISDEVLKLISNRHQTPLDDGVLIRSPDTHPNLQRSPE  
s2:
...................................................VNKVPASLLEKVCNPRLVAFTAMDLARTRFAPL.........YTSIEQQVAKRFSKDPSKLQPTPG................................................................................VRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNLMRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVH............................VLIRSPDTHPNLQR...  

"Adjust for PAE" is checked in the distance restraint options, but the
reference model has no PAE matrix assigned. This option has been ignored.  

> isolde restrain distances "#1.2/L3" templateAtoms "#6/L3" perChain false
> adjustForConfidence false useCoordinateAlignment false kappa 4.40 fallOff
> 2.50 groupName "Reference Distance Restraints"

ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
[Repeated 1 time(s)]Computing secondary structure  

> isolde restrain torsions #1.2/L3 templateResidues #6/L3 adjustForConfidence
> false sidechains true springConstant 250.00 alpha 0.20

ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
[Repeated 1 time(s)]Computing secondary structure  

> select ~#1/L3&#1

270747 atoms, 274109 bonds, 40 pseudobonds, 16513 residues, 19 models selected  

> isolde ignore sel

ISOLDE: currently ignoring 16513 residues in model 1.2  

> select #1/L3

3991 atoms, 4034 bonds, 1 pseudobond, 246 residues, 2 models selected  

> isolde sim start #1.2/L3

ISOLDE: started sim  

> select #6:312-325

235 atoms, 237 bonds, 14 residues, 1 model selected  

> style sel stick

Changed 235 atom styles  

> style sel stick

Changed 235 atom styles  

> show sel atoms

> select #1

274738 atoms, 278143 bonds, 41 pseudobonds, 16759 residues, 23 models selected  

> hide sel atoms

[Repeated 1 time(s)]

> show sel cartoons

> select ~#1/L3&#1

270747 atoms, 274109 bonds, 40 pseudobonds, 16513 residues, 23 models selected  

> hide sel atoms

> hide sel cartoons

> ui mousemode right "isolde tug residue"

> select #1/L3:94-117

383 atoms, 387 bonds, 24 residues, 1 model selected  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 5 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> hide #!6 models

> select #1

274738 atoms, 278143 bonds, 41 pseudobonds, 16759 residues, 23 models selected  

> show sel atoms

> show sel cartoons

> select #1/L3

3991 atoms, 4034 bonds, 1 pseudobond, 246 residues, 2 models selected  

> isolde sim start #1.2/L3

ISOLDE: started sim  

> isolde sim stop discardTo start

Sim termination reason: None  
reverting to start  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde ~ignore

> isolde sim start #1.2/L3

ISOLDE: started sim  

> close #1.2.9

> ui tool show "Ramachandran Plot"

> isolde pepflip #1.2/Kp:84

[Repeated 3 time(s)]

> isolde pepflip #1.2/L3:122

> close #1.2.7

> isolde pepflip #1.2/L3:92

> isolde pepflip #1.2/L3:119

> isolde pepflip #1.2/L3:105

[Repeated 3 time(s)]

> isolde pepflip #1.2/L3:117

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/L3:117

> isolde pepflip #1.2/L3:118

> isolde pepflip #1.2/L3:119

> isolde pepflip #1.2/L3:120

[Repeated 1 time(s)]

> ui tool show "Ramachandran Plot"

[Repeated 1 time(s)]

> isolde pepflip #1.2/L3:122

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/L3:122

> isolde pepflip #1.2/L3:121

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 6 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> volume #1.1.1.1 level 0.176

> volume #1.1.1.1 level 0.1484

> volume #1.1.1.1 level 0.1718

> isolde sim start #1.2/L3:67

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/L3:82-100

ISOLDE: started sim  

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> ui tool show "Ramachandran Plot"

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> show #8 models

> select clear

> delete #8:1-13

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp.mrc"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #9, grid size
500,500,500, pixel 1.21, shown at level 0.118, step 2, values float32  

> hide #8 models

> transparency #9.1#1.1.1.1.1 0

> transparency #9.1#1.1.1.1.1 50

> volume #9 step 1

> volume #9 level 0.2216

> delete #1/K5

> hide #!9 models

> show #8 models

> combine #1,8

Remapping chain ID 'A' in AlphaFold A0A640KIH4 #8 to 'F'  

> save /Users/rafaelrocha/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV7.cif

Not saving entity_poly_seq for non-authoritative sequences  

[Repeated 3 time(s)]

> close #1

> clipper associate #9 toModel #10

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #1.1.1.1, grid size
500,500,500, pixel 1.21, shown at level 0.203, step 1, values float32  

> volume #1.1.1.1 style surface

> transparency #1.1.1.1.1 50

> addh #1 hbodn f

Expected a keyword  

> addh #1 hbond false

Summary of feedback from adding hydrogens to combination #1.2  
---  
warning | Not adding hydrogens to combination #1.2/GT ALA 93 CA because it is missing heavy-atom bond partners  
notes | No usable SEQRES records for combination (#1.2) chain A; guessing termini instead  
No usable SEQRES records for combination (#1.2) chain A0; guessing termini
instead  
No usable SEQRES records for combination (#1.2) chain AG; guessing termini
instead  
No usable SEQRES records for combination (#1.2) chain AU; guessing termini
instead  
No usable SEQRES records for combination (#1.2) chain Ab; guessing termini
instead  
84 messages similar to the above omitted  
Termini for combination (#1.2) chain L3 determined from SEQRES records  
Termini for combination (#1.2) chain F determined from SEQRES records  
Chain-initial residues that are actual N termini: combination #1.2/A ALA 34,
combination #1.2/A0 PRO 204, combination #1.2/AG PHE 18, combination #1.2/AU
LYS 35, combination #1.2/Ab GLU 206, combination #1.2/Aj LYS 208, combination
#1.2/Aq LYS 25, combination #1.2/Ar LEU 23, combination #1.2/B ALA 23,
combination #1.2/BI ALA 23, combination #1.2/BK THR 37, combination #1.2/BP
GLY 22, combination #1.2/C SER 85, combination #1.2/C0 ILE 33, combination
#1.2/C1 ILE 33, combination #1.2/C2 ILE 33, combination #1.2/C3 ILE 33,
combination #1.2/C4 SER 34, combination #1.2/C5 ILE 33, combination #1.2/C6
ILE 33, combination #1.2/C7 ILE 33, combination #1.2/C8 ILE 33, combination
#1.2/C9 ILE 33, combination #1.2/D TYR 18, combination #1.2/D6 VAL 7,
combination #1.2/E PHE 33, combination #1.2/E1 LEU 51, combination #1.2/E4 GLN
35, combination #1.2/Ek ASN 26, combination #1.2/Eq ASN 62, combination
#1.2/Es VAL 2, combination #1.2/Ev GLY 3, combination #1.2/F9 HIS 37,
combination #1.2/FF HIS 98, combination #1.2/FH VAL 18, combination #1.2/FL
MET 1, combination #1.2/FO PHE 12, combination #1.2/Fy PRO 60, combination
#1.2/Fz VAL 58, combination #1.2/GT ALA 6, combination #1.2/I0 SER 160,
combination #1.2/IE LYS 26, combination #1.2/IY SER 2, combination #1.2/Il TYR
26, combination #1.2/Ix ASP 152, combination #1.2/Iy THR 22, combination
#1.2/J6 THR 2, combination #1.2/JC GLU 22, combination #1.2/JI PRO 11,
combination #1.2/JJ MET 1, combination #1.2/JN ALA 2, combination #1.2/Jw VAL
21, combination #1.2/Jx LYS 11, combination #1.2/KI THR 26, combination
#1.2/Ke ALA 44, combination #1.2/Kp PRO 53, combination #1.2/Ks GLU 4,
combination #1.2/LG TRP 20, combination #1.2/LO TYR 37, combination #1.2/LR
SER 78, combination #1.2/LY PRO 182, combination #1.2/M PRO 2, combination
#1.2/Mg ILE 36, combination #1.2/Mq SER 34, combination #1.2/Mr THR 38,
combination #1.2/NF LYS 30, combination #1.2/NM TYR 82, combination #1.2/Np
MET 1, combination #1.2/R MET 1, combination #1.2/TB MET 18, combination
#1.2/Y MET 1, combination #1.2/a TYR 3, combination #1.2/t0 THR 38,
combination #1.2/t1 THR 2, combination #1.2/t2 TYR 37, combination #1.2/t3 PHE
18, combination #1.2/t4 LEU 23, combination #1.2/t5 THR 26, combination
#1.2/t6 MET 1, combination #1.2/t7 MET 1, combination #1.2/t8 VAL 21,
combination #1.2/t9 ASP 152, combination #1.2/ta MET 1, combination #1.2/tb
SER 160, combination #1.2/tc THR 22, combination #1.2/td TYR 26, combination
#1.2/te GLU 4, combination #1.2/tf ALA 2, combination #1.2/tg PRO 182,
combination #1.2/AG PHE 18, combination #1.2/Ar LEU 23, combination #1.2/I0
SER 160, combination #1.2/Il TYR 26, combination #1.2/Ix ASP 152, combination
#1.2/Iy THR 22, combination #1.2/J6 THR 2, combination #1.2/JI PRO 11,
combination #1.2/JI GLU 259, combination #1.2/JJ MET 1, combination #1.2/JN
ALA 2, combination #1.2/Jw VAL 21, combination #1.2/Jx LYS 11, combination
#1.2/KI THR 26, combination #1.2/Ke ALA 44, combination #1.2/Kp PRO 53,
combination #1.2/Ks GLU 4, combination #1.2/LG TRP 20, combination #1.2/LO TYR
37, combination #1.2/LR SER 78, combination #1.2/LY PRO 182, combination
#1.2/M PRO 2, combination #1.2/Mg ILE 36, combination #1.2/Mq SER 34,
combination #1.2/Mr THR 38, combination #1.2/NF LYS 30, combination #1.2/NF
ARG 189, combination #1.2/NM TYR 82, combination #1.2/Np MET 1, combination
#1.2/TB MET 18, combination #1.2/Y MET 1, combination #1.2/t0 THR 38,
combination #1.2/t1 THR 2, combination #1.2/t2 TYR 37, combination #1.2/t3 PHE
18, combination #1.2/t4 LEU 23, combination #1.2/t5 THR 26, combination
#1.2/t6 MET 1, combination #1.2/t7 MET 1, combination #1.2/t8 VAL 21,
combination #1.2/t9 ASP 152, combination #1.2/ta MET 1, combination #1.2/tb
SER 160, combination #1.2/tc THR 22, combination #1.2/td TYR 26, combination
#1.2/te GLU 4, combination #1.2/tf ALA 2, combination #1.2/tg PRO 182,
combination #1.2/R MET 1, combination #1.2/A ALA 34, combination #1.2/A0 PRO
204, combination #1.2/AU LYS 35, combination #1.2/AU GLN 151, combination
#1.2/AU GLN 436, combination #1.2/Ab GLU 206, combination #1.2/Ab THR 521,
combination #1.2/Aj LYS 208, combination #1.2/Aq LYS 25, combination #1.2/B
ALA 23, combination #1.2/BI ALA 23, combination #1.2/BK THR 37, combination
#1.2/BK GLN 151, combination #1.2/BK VAL 437, combination #1.2/BP GLY 22,
combination #1.2/C SER 85, combination #1.2/C0 ILE 33, combination #1.2/C1 ILE
33, combination #1.2/C2 ILE 33, combination #1.2/C3 ILE 33, combination
#1.2/C4 SER 34, combination #1.2/C5 ILE 33, combination #1.2/C6 ILE 33,
combination #1.2/C7 ILE 33, combination #1.2/C8 ILE 33, combination #1.2/C9
ILE 33, combination #1.2/D TYR 18, combination #1.2/D ILE 234, combination
#1.2/D6 VAL 7, combination #1.2/D6 VAL 63, combination #1.2/E PHE 33,
combination #1.2/E GLN 151, combination #1.2/E GLN 438, combination #1.2/E1
LEU 51, combination #1.2/E1 ASP 217, combination #1.2/E4 GLN 35, combination
#1.2/Ek ASN 26, combination #1.2/Eq ASN 62, combination #1.2/Es VAL 2,
combination #1.2/Ev GLY 3, combination #1.2/F9 HIS 37, combination #1.2/FF HIS
98, combination #1.2/FF MET 124, combination #1.2/FH VAL 18, combination
#1.2/FL MET 1, combination #1.2/FO PHE 12, combination #1.2/Fy PRO 60,
combination #1.2/Fz VAL 58, combination #1.2/IE LYS 26, combination #1.2/IE
VAL 199, combination #1.2/IY SER 2, combination #1.2/JC GLU 22, combination
#1.2/a TYR 3, combination #1.2/GT ALA 6  
Chain-initial residues that are not actual N termini: combination #1.2/AU GLN
151, combination #1.2/AU GLN 436, combination #1.2/Ab THR 521, combination
#1.2/BK GLN 151, combination #1.2/BK VAL 437, combination #1.2/D ILE 234,
combination #1.2/D6 VAL 63, combination #1.2/E GLN 151, combination #1.2/E GLN
438, combination #1.2/E1 ASP 217, combination #1.2/FF MET 124, combination
#1.2/IE VAL 199, combination #1.2/JI GLU 259, combination #1.2/NF ARG 189,
combination #1.2/L3 VAL 52, combination #1.2/L3 VAL 312, combination #1.2/F
ALA 14  
Chain-final residues that are actual C termini: combination #1.2/A PRO 357,
combination #1.2/A0 LYS 685, combination #1.2/AG SER 196, combination #1.2/AU
VAL 574, combination #1.2/Ab ARG 690, combination #1.2/Aj HIS 690, combination
#1.2/Aq GLN 187, combination #1.2/Ar TRP 118, combination #1.2/B LYS 160,
combination #1.2/BI GLN 187, combination #1.2/BK VAL 574, combination #1.2/BP
GLN 187, combination #1.2/C MET 349, combination #1.2/C0 SER 106, combination
#1.2/C1 SER 106, combination #1.2/C2 SER 106, combination #1.2/C3 SER 106,
combination #1.2/C4 SER 106, combination #1.2/C5 SER 106, combination #1.2/C6
SER 106, combination #1.2/C7 SER 106, combination #1.2/C8 SER 106, combination
#1.2/C9 SER 106, combination #1.2/D VAL 258, combination #1.2/D6 THR 70,
combination #1.2/E GLY 575, combination #1.2/E1 GLY 239, combination #1.2/E4
GLY 203, combination #1.2/Ek SER 103, combination #1.2/Eq TYR 145, combination
#1.2/Es HIS 136, combination #1.2/Ev ALA 386, combination #1.2/F9 GLN 103,
combination #1.2/FF PRO 174, combination #1.2/FH VAL 157, combination #1.2/FL
GLY 233, combination #1.2/FO ALA 159, combination #1.2/Fy ALA 117, combination
#1.2/Fz VAL 105, combination #1.2/GT ALA 93, combination #1.2/I0 LYS 383,
combination #1.2/IE GLY 204, combination #1.2/IY ASN 295, combination #1.2/Il
GLU 104, combination #1.2/Ix ILE 279, combination #1.2/Iy GLN 115, combination
#1.2/J6 PHE 199, combination #1.2/JC GLU 183, combination #1.2/JI LYS 491,
combination #1.2/JJ ILE 549, combination #1.2/JN VAL 108, combination #1.2/Jw
PHE 144, combination #1.2/Jx ASP 124, combination #1.2/KI GLU 225, combination
#1.2/Ke LEU 138, combination #1.2/Kp GLU 224, combination #1.2/Ks ALA 156,
combination #1.2/LG SER 123, combination #1.2/LO LYS 342, combination #1.2/LR
GLY 148, combination #1.2/LY ALA 345, combination #1.2/M PHE 103, combination
#1.2/Mg ALA 250, combination #1.2/Mq LYS 90, combination #1.2/Mr LEU 147,
combination #1.2/NF SER 246, combination #1.2/NM MET 144, combination #1.2/Np
VAL 283, combination #1.2/R HIS 62, combination #1.2/TB THR 81, combination
#1.2/Y ILE 210, combination #1.2/a GLN 96, combination #1.2/t0 LEU 147,
combination #1.2/t1 PHE 199, combination #1.2/t2 LYS 342, combination #1.2/t3
SER 196, combination #1.2/t4 TRP 118, combination #1.2/t5 GLU 225, combination
#1.2/t6 ILE 549, combination #1.2/t7 VAL 283, combination #1.2/t8 PHE 144,
combination #1.2/t9 ILE 279, combination #1.2/ta ILE 210, combination #1.2/tb
LYS 383, combination #1.2/tc GLN 115, combination #1.2/td GLU 104, combination
#1.2/te ALA 156, combination #1.2/tf VAL 108, combination #1.2/tg ALA 345,
combination #1.2/F TYR 607, combination #1.2/AG SER 196, combination #1.2/Ar
TRP 118, combination #1.2/I0 LYS 383, combination #1.2/Il GLU 104, combination
#1.2/Ix ILE 279, combination #1.2/Iy GLN 115, combination #1.2/J6 PHE 199,
combination #1.2/JI PHE 252, combination #1.2/JI LYS 491, combination #1.2/JJ
ILE 549, combination #1.2/JN VAL 108, combination #1.2/Jw PHE 144, combination
#1.2/Jx ASP 124, combination #1.2/KI GLU 225, combination #1.2/Ke LEU 138,
combination #1.2/Kp GLU 224, combination #1.2/Ks ALA 156, combination #1.2/LG
SER 123, combination #1.2/LO LYS 342, combination #1.2/LR GLY 148, combination
#1.2/LY ALA 345, combination #1.2/M PHE 103, combination #1.2/Mg ALA 250,
combination #1.2/Mq LYS 90, combination #1.2/Mr LEU 147, combination #1.2/NF
LEU 183, combination #1.2/NF SER 246, combination #1.2/NM MET 144, combination
#1.2/Np VAL 283, combination #1.2/TB THR 81, combination #1.2/Y ILE 210,
combination #1.2/t0 LEU 147, combination #1.2/t1 PHE 199, combination #1.2/t2
LYS 342, combination #1.2/t3 SER 196, combination #1.2/t4 TRP 118, combination
#1.2/t5 GLU 225, combination #1.2/t6 ILE 549, combination #1.2/t7 VAL 283,
combination #1.2/t8 PHE 144, combination #1.2/t9 ILE 279, combination #1.2/ta
ILE 210, combination #1.2/tb LYS 383, combination #1.2/tc GLN 115, combination
#1.2/td GLU 104, combination #1.2/te ALA 156, combination #1.2/tf VAL 108,
combination #1.2/tg ALA 345, combination #1.2/R HIS 62, combination #1.2/A PRO
357, combination #1.2/A0 LYS 685, combination #1.2/AU LEU 139, combination
#1.2/AU ASP 430, combination #1.2/AU VAL 574, combination #1.2/Ab VAL 515,
combination #1.2/Ab ARG 690, combination #1.2/Aj HIS 690, combination #1.2/Aq
GLN 187, combination #1.2/B LYS 160, combination #1.2/BI GLN 187, combination
#1.2/BK GLY 138, combination #1.2/BK ASP 430, combination #1.2/BK VAL 574,
combination #1.2/BP GLN 187, combination #1.2/C MET 349, combination #1.2/C0
SER 106, combination #1.2/C1 SER 106, combination #1.2/C2 SER 106, combination
#1.2/C3 SER 106, combination #1.2/C4 SER 106, combination #1.2/C5 SER 106,
combination #1.2/C6 SER 106, combination #1.2/C7 SER 106, combination #1.2/C8
SER 106, combination #1.2/C9 SER 106, combination #1.2/D LYS 206, combination
#1.2/D VAL 258, combination #1.2/D6 LEU 52, combination #1.2/D6 THR 70,
combination #1.2/E LEU 139, combination #1.2/E ALA 429, combination #1.2/E GLY
575, combination #1.2/E1 GLU 123, combination #1.2/E1 GLY 239, combination
#1.2/E4 GLY 203, combination #1.2/Ek SER 103, combination #1.2/Eq TYR 145,
combination #1.2/Es HIS 136, combination #1.2/Ev ALA 386, combination #1.2/F9
GLN 103, combination #1.2/FF TYR 118, combination #1.2/FF PRO 174, combination
#1.2/FH VAL 157, combination #1.2/FL GLY 233, combination #1.2/FO ALA 159,
combination #1.2/Fy ALA 117, combination #1.2/Fz VAL 105, combination #1.2/IE
VAL 194, combination #1.2/IE GLY 204, combination #1.2/IY ASN 295, combination
#1.2/JC GLU 183, combination #1.2/a GLN 96, combination #1.2/GT ALA 93  
Chain-final residues that are not actual C termini: combination #1.2/AU LEU
139, combination #1.2/AU ASP 430, combination #1.2/Ab VAL 515, combination
#1.2/BK GLY 138, combination #1.2/BK ASP 430, combination #1.2/D LYS 206,
combination #1.2/D6 LEU 52, combination #1.2/E LEU 139, combination #1.2/E ALA
429, combination #1.2/E1 GLU 123, combination #1.2/FF TYR 118, combination
#1.2/IE VAL 194, combination #1.2/JI PHE 252, combination #1.2/NF LEU 183,
combination #1.2/L3 HIS 283, combination #1.2/L3 ARG 325  
Adding 'H' to combination #1.2/F ALA 14  
combination #1.2/L3 ARG 325 is not terminus, removing H atom from 'C'  
4464 hydrogens added  
  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/chainK5.cif"

Summary of feedback from opening
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/chainK5.cif  
---  
warnings | Unknown polymer entity '46' on line 356  
Missing or incomplete sequence information. Inferred polymer connectivity.  
  
  
Chain information for chainK5.cif #9  
---  
Chain | Description  
K5 | No description available  
  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 90 residues in model #1.2 to IUPAC-IUB
standards.  

> select #1/K5

Nothing selected  

> changechains #1/A K5

Chain IDs of 324 residues changed  

> select #1/K5

5332 atoms, 5377 bonds, 324 residues, 1 model selected  

> hide #!9 models

> hide #8 models

> changechains #1/K5 A

Chain IDs of 324 residues changed  

> changechains #1/F K5

Chain IDs of 594 residues changed  

> select #1/K5

9024 atoms, 9120 bonds, 594 residues, 1 model selected  

> select #1/A

5332 atoms, 5377 bonds, 324 residues, 1 model selected  

> select #1/K5

9024 atoms, 9120 bonds, 594 residues, 1 model selected  

> matchmaker #9 to #1.2

Computing secondary structure  
Parameters  
---  
Chain pairing | bb  
Alignment algorithm | Needleman-Wunsch  
Similarity matrix | BLOSUM-62  
SS fraction | 0.3  
Gap open (HH/SS/other) | 18/18/6  
Gap extend | 1  
SS matrix |  |  | H | S | O  
---|---|---|---  
H | 6 | -9 | -6  
S |  | 6 | -6  
O |  |  | 4  
Iteration cutoff | 2  
  
Matchmaker combination, chain K5 (#1.2) with chainK5.cif, chain K5 (#9),
sequence alignment score = 2215.7  
RMSD between 387 pruned atom pairs is 1.201 angstroms; (across all 498 pairs:
2.475)  
  

> color #9 bychain

> color #9 byhetero

> color modify #9 hue + 50

Computing secondary structure  
s1:
............................................................................................................................................................................................................................................................................ASKEEQIKKNTKIAIEMIRRYKGETPMSYTRKHTATIEQLEREIEALLGGAQKMRKATTD.......DQPMDKLGLMERCLRHALWSYHKDEGKYDFDEIARWVVYTPEDEVKLAQMKRQVEAKSKLAAYRAKRAEQ......GLPEAPVPQISWEEEYKNVTDRELVNEKRLRYDTIAANTMERDEAQIEAVLQQYRKPIQDKRLDDLVDLLERFKPVLAREAIMQRLTIKHLEGQLGVWRYMDWCPEVRDRAELEVDISGFQWWSPLEERRLLPVRLRSVNEVREIMAQTQSSKAAEASAHSPQASQSAGDGDRERLLKEVLALQARIHQRDDAP  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQ..PELR.....ADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSH.ALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLT.NELESIPP..................................................................................................  
s1:
.......................................................................................................................................................................................PAEHKGRVGYVSQVIGAVVDVHFS.........EGVPPVLTALDVTEDLG..RDEPLTLE....IVQHLDANTGRCIAMQTTDLLKL.KSKVVSTGGNISVPVGRETLGRIFNV.LGDAIDQRG...........PVGEKMRMAIHAEAPKLADQAAEDTILTTGIKVIDLILPYCKGG..KIGLFGGAGVGKTVIIMELINNVAKGHGGFSVFAGVGERTREGTDLYLEMMQSKVIDLKGDSKCVLVYGQMNEPPGARARVAQSALTMAEYFRDVEGQNVLLFIDNIFRFTQANSEVSALLGRIPAAVGYQPTLAEDLGMLQERITSTTKGSITSVQAVYVPADDITDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMDPDVIDVNHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQVAEVFTGMTGHYVQLNDTVESFSGLLMGSYDQIPEMAFYMVGGINSVLEKAKAMAEEAAAMEK  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDV.VSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHG.ANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNN..KGD...IPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHD....KSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLA..YRPVHMEMLTNELESIPP........................................................................................................................................................................................  
s1:
......................................................................................................................................................................................................................................................................................................................................................FFGKGWDNAALDTIFSSMLRKPEVNDRIRTQYASTMD...PRDADVLRRLGEVSKENKTFIRVFLPPHL.GDPHRLLKCYSLMAYPILDDKGGQLKVEM.DGCKLD.AFADPDDDYSKVVIPHIELVEYLAKSLLETMKWEATPRGAASLLESLYRGAEIPDHVFQTPAVIERLEDYKDGNKVIS  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDI..PIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYL.DDANGTVRLAYRPVHMEMLTNEL...ESIPP.......................  
s1:
..........................................................................................................................................................................................................KATEMIGYVHSIDGTIATLIPAPGNPGVAYNTIIMIQVSPTTFAAGLVFNLEKDGRIGIILMD..NITEVQSGQKVMATGKLLYIPV......GAGVL..GKVVNPLGHE....VPVGLQTLGKVDAGAPNIVSRSPVNYNL...LTGFKAVDTMI....PIGRGQRELIVGDRQTGKTSIAVSTIINQVRNNQQIL....SKNAVISIYVSIGQRCSNVARIHRLLRSYG.ALRY..TTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDD.LSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNVAMKAVAGKLKGILAEYRKLAADQVQTVPMIRGARFVALFNQKNPSFFMNALVSLYACLNGYLDDVKVNYAKLYEYLLVNKDLSVMYGTATNKFFYMYVQQLNYVIRFFTLNHPILNAEVEEMLKQHTHLFLQHYQSKMNAIKTEKEIKALKNLLYSCKRAV  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPA...EDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFA.GVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVP.GLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPEL...RADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQ.TGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVV.RMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP.......................................................................................................................................................................................................................................................  
s1:
.........................................................................................................................................................................................EHKGRVGYVSQVIGAVVDVHFS.........EGVPPVLTALDVTEDLGRDEPLTLEIVQHLDANTGRCIAMQ..TTDLLKL....KSKVVSTGGNISVPVGRETLGRIFNV.LGDAIDQRG...........PVGEKMRMAIHAEAPKLADQAAEDTILTTGIKVIDLILPYCKGG..KIGLFGGAGVGKTVIIMELINNVAKGHGGFSVFAGVGERTREGTDLYLEMMQSKVIDLKGDSKCVLVYGQMNEPPGARARVAQSALTMAEYFRDVEGQNVLLFIDNIFRFTQANSEVSALLGRIPAAVGYQPTLAEDLGMLQERITSTTKGSITSVQAVYVTDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMDPDVIDVNHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQVAEVFTGMTGHYVQLNDTVESFSGLLMGSYDQIPEMAFYMVGGINSVLEKAKAMAEEAAAMEKQRRAR  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHG.ANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNN..KGD...IPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHD....KSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLA..YRPVHMEMLTNELESIPP........................................................................................................................................................................................  
s1:
........................................................................................................................................................................................................KGRVGYVSQVIGAVVDVHFSEGVPPVLTALDVTEDLGRDEPLTLEIVQHLDANTGRCIAMQ..TTDLLKL....KSKVVSTGGNISVPVGRETLGRIFNV.LGDAIDQRG...........PVGEKMRMAIHAEAPKLADQAAEDTILTTGIKVIDLILPYCKGGKI..GLFGGAGVGKTVIIMELINNVAKGHGGFSVFAGVGERTREGTDLYLEMMQSKVIDLKGDSKCVLVYGQMNEPPGARARVAQSALTMAEYFRDVEGQNVLLFIDNIFRFTQANSEVSALLGRIPAAVGYQPTLAEDLGMLQERITSTTKGSITSVQAVYVPADDITDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMDPDVIDVNHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQVAEVFTGMTGHYVQLNDTVESFSGLLMGSYDQIPEMAFYMVGGINSVLEKAKAMAEEAAAMEENKAAH  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCT....GDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHG.ANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNN..KGD...IPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHD....KSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLA..YRPVHMEMLTNELESIPP.............................................................................................................................................................................................  
s1:
KYDLFGYEVDTNTAPWIEKVKKCR.YYDEAGEVLVSMNVKNCPPDLETYNATLQKIFEAPSKQEKPVENESKFCAMMDLMEEMQHRNKVKPNEESWTWVMKECVQSGQFRLGYCVAKLMEAEF.............KRVPEDLVKQNEANAAKAKADGKEHPSTLAQQQSLFDIKIQ....................................................................................................................................................................................................................................................................................................................................................  
s2:
............AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDV....ACISKLY..PSRS.HTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.....................................................................................LHFPLSPPPIEIDYLDSDPLEFAVRTEARRWGFDDLQYMRELAFVRIKENPSIGDFRRMTPEERRDLFWGSD....RQDFFRYITLKLTGHPEHLYHRGW..................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPF.LRTK......DGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLI..TEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
....................................................................................................................................................................................................................................ASDLKMVSLHKILI...GEVQFRNNALLKACNIEHNFGPTWKSEIEAYA...KSLPAEEKNCLERQIARVSMTRYTTRELAEYCGEGPEHVDAVAREANIAQAKVYAQKNGADKLETYVKAEAKNAGWSEAETKKFMDAVKAAK........................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPT.....VHYSMGGVP.TLWTGEVISPRDGDDNAIVPGLLAAGECACASVH....GANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
AKKYDLFGYEVDTNTAPWIEKVKKCR.YYDEAGEVLVSMNVKNCPPDLETYNATLQKIFEAPSKQEKPVENESKFCAMMDLMEEMQHRNKVKPNEESWTWVMKECVQSGQFRLGYCVAKLMEAEF.............KRVPEDLVKQNEANAAKAKADGKEHPSTLAQQQSLFDIKIQ....................................................................................................................................................................................................................................................................................................................................................  
s2:
..............AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDV....ACISKLY..PSRS.HTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.....................................................................................................................................................................................................TEMIGYVH.......SIDGTIATLIPAPGNPGVAYNTIIMIQVSPTTFAAGLVFNLEKDGRIGIILMD..NITEVQSGQKVMATGKLLYIPV......GAGVL..GKVVNPLGHE....VPVGQTLGKVDAGAPNIVSRSPVNYNL...LTGFKAVDTMI....PIGRGQRELIVGDRQTGKTSIAVSTIINQVRNNQQIL....SKNAVISIYVSIGQRCSNVARIHRLLRSYG.ALRY..TTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDDL.SKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNVAMKAVAGKLKGILAEYRKLAADVQTVPMIRGARFVALFNQKNPSFFMNALVSLYACLNGYLDDVKVNYAKLYEYLLVNKDLSVMYGTATNKFFYMYVQQLNYVIRFFTLNHPILNAEVEEMLKQHTHLFLQHYQSKMNAIKTEKEIKALKNLLYSCKRAV  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPA...EDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFA.GVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPEL...RADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQ.TGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVV.RMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP......................................................................................................................................................................................................................................................  
s1:
GAKKYDLFGYEVDTNTAPWIEKVKKCRYYDEAGEVLVSMN.VKNCPPDLETYNATLQKIFEAPSKQEKPVENESKFCAMMDLMEEMQHRNKVKPNEESWTWVMKECVQSGQFRLGYCVAKLMEAE...FKRVPEDLVKQNEANAAKAKADGK....EHPSTLAQQQSLFDIKIQ..........................................................................................................................................................................................................................................................................................................................................................  
s2:
...............AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDV....ACISKLY..PSRS.HTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
..........................................................................................................................................................................................................................SIAVIAAGAPAALLQAVSSILSKATGGAVKATQATSAASNAVVV......GMQAPRGVYACVAEPPSTASGPYAGVKTV.VVRAILPRSAPDT......................MQVRDILDVYPASGIACEKETAEAVKNFTKAAKVAVEKAKAMKATRVTLVM.KPATKYERLNGLFRETCTKTIEAA...GLSVETSTTAAATNTLI..MFPEKMSVVMVSDD..PVCENVQYAYAGAVGGV.HTTYYTDSGNKIYGGHSYRSVAM.ALAEELKSLGMKAEAAKVEAAVQKSPRNAAAAM  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITE.RDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTV.RLAYRPVHMEMLTNELESIPP......................  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
....................................................................................................SIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.........................................................................................................................................................................................................................YTPSEELKKLYASDFERAQF.PANIV.PSDSVTFAKFLYKAV...........EPKGSFDAILKDFQTIAAAIPKLPIFWERTVVVSEVNEFKSL..........SAPTIFTLEWMQSNGMLDLLPDVAEVYETYV......SAKMKRVTAKIYVAPGKEQDRALVDKARKVAEQVVKDNKQLAGYTLVPKVLVDRSIVEGFAVDVQGTYVNEAVGRKIETEVLRKYLDSLSLY.DAEELKSGV.......................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDK..SPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
..............................................................................................................................................................................................................................................................................................................................................................................................................................................VALNWRDHGISYVKYLNVATEALHMATKDKARAKYSRFSTPNYIALVKKVPAFT................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRL..AYRPVHMEMLTNELESIPP  
s1:
............................................................................................................................................................................................................FFKATEMIGYVHSIDGTIATLIPAPGNPGVAYNTIIMIQVSPTTFAAGLVFNLEKDGRIGIILMD..NITEVQSGQKVMATGKLLYIPV......GAGVL..GKVVNPLGHE....VPVGLQTLGKVDAGAPNIVSRSPVNYNL...LTGFKAVDTMI....PIGRGQRELIVGDRQTGKTSIAVSTIINQVRNNQQIL....SKNAVISIYVSIGQRCSNVARIHRLLRSYG.ALRY..TTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDD.LSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNVAMKAVAGKLKGILAEYRKLAAQTVPMIRGARFVALFNQKNPSFFMNALVSLYACLNGYLDDVKVNYAKLYEYLLVNKDLSVMYGTATNKFFYMYVQQLNYVIRFFTLNHPILNAEVEEMLKQHTHLFLQHYQSKMNAIKTEKEIKALKNLLYSCKRAVG  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTS....AKSCTGDGTAMVARAGLPA...EDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFA.GVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVP.GLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPEL...RADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQ.TGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVV.RMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP.....................................................................................................................................................................................................................................................  
s1:
..............................................................................................................................................................................LSLLLCVHFSAIHRPPPPVPFTALAAFLYALT.LTAPVAEQRSGSSLHPQIEVGTEIEDMALFHLVVLPLVFFAAMCIGRG.....................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKS..KYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...............................................................................................................................................................................................................................................................................QMKVELTMQYLDEWMLRWRKFQTESDWQIEKNRQWWRKANIVTAGAVMGGLVMYTAGNATIRRQFGAPHFFDIGVDGK.LKEAICDTMTSRWRYTPQGYGRVMLVGLPTFFVFAISEHIQERRRLRAYVRQN.TVFGEQARRLVQNGK.IEEYLAVDIKASLPQNQTQLYAG.............................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVP.TVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANR..LGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDS...MQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.........................................................................................................................................................................................................NMFLFKDPVRRPQLSPEERAKVKINYAEWPEEFRDYDPDDPYKNSPEIIE......GLSSWNLFLWGV.ECAFIYQFYEVVFPKS....................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................................................................................................................................................................................................................................................................................................................NPVDHFRPNL.KFLSVYVE.....HQYVVDKWLHVKENWLKPWYLPWW.TPMYQAMTWYSQRNRNLMLVENHLNYRPYRYRRNDEDRENPY....................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
........................................................................................................................................................................................................................................................................................VFFSTYRSKRIVAPGFLKGPVMASRAFFDYYFQRAWCGCVQWVIPGEVRLWACGVPVIYFIHRYHNDHSLEPDFVEKAMIQRWGGSL.EEVRKLSPQDQLRIRAFTDLEKLYSAYGPKDTIVQPPGDLLPGKDYYH......................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDD...........NAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRK...QPELRADAGE......ASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
GTWSVLKKNCLNFVPGLALFASQSRDAFATWMKIYNRGYKYGPQEFSDQAEAYTPDYWKRGHSQEKNMWVDMKLSEEVSQKELAQLMHYKQDLWRMGHGLGLSLFLGGYALIPAFFCLSSDTFAPSCFCKTEEEKKAWREAQDMYRYRSAPSYIMDTKWHFD..FHAYPWNATQERAWDDLFEKNNVRRDPKVL.RPAAEMYDGFLKFYQIRRKSLRHLARSMNLP..TFPLLSRTCASTRVKDYWNLAWNEDYMVIT...QKLHHQMSDEDLHDYAWRRFLAPY....DKNLSRDEIMTRVNDYHEFLGPKFVEEGKAP..NMIILTNYVLGYYNDPAYLVE..........DISALDGNDFEYMAHYGKDAFLRRLEFENG..PLRDQVEAHTQKLIADRAAAAAAEA....................................................................................................................................................................................  
s2:
...........................................................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQ.YGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
HLEPMSVWYLSSWTCVWWYSFFFWLPVLWADMIVPSFVYNKLPVIHFIQEKRAEQKLRRVLDETYTQ.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................  
s2:
........................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................................HPPKLEDIPPSSATKGFFGAYMARLIDIKWMMNRSVELGREYYISAPTLYLFLWMFCWKGFVIMRYGDGKPP.......................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.................................................................................................................................................................................................................................................................................................................................................................................................................................................VGNGPTFHTAGDNN.NTSEIQNAFPINERGIRSSSPFPEPNTAIYDSYMPWTYFQPIDVKVDKMPAPEAKYYQHHTKKPWDVSTTDLIEIQSRKKYVQGVGYFLMMIYLYFLMPKEKSYSGTTGSDGFYVMLPKNQPEKFV  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRP.VHMEMLTNELESIPP...........................................................................  
s1:
................................................................................................................................................................................................................................................................................................................................................................................................................MFVFFVCDLVIMRILLCFCYSVWSRIIFVLFYNVFYICTELMFCIFDVYLFVGLCMFICLWFVLFNFYGLIVY..YCITYLNVYILFCIVFMYYMAFLFCFCFLLDFILFGSLLVGDAFMDVFFLRYLLCVLECFSLLCRCISTFLRMFCNLLSSHFLMLMFCDFVYFFIIFFLFFIMCDFIYFIIFTFAMLFCIIFYLFLYALDMFCALLQIFIFCNMIMQLIMDFLLLLSFHG  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSH...ALVHD........KSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDD.ANGTVRLAYRPVHMEMLTNELESIPP.............................................................................................................................  
s1:
................................................................................................................................................................................................FTVPVALCTKQVAAMDEPLKRHIDAYEARGEDVTIAVWREYVDGQRALLPYRWAKFRNEVTYLTSG....QIALTDLAFADLLLFVRFLTKCLFIFIVAVMAGRRSVFPSLE......PTSPFVEEIVKNWQPNRLRRVAGAEYMARDQAAAAAAAAA........................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTI...LCT...GGYGRVYFTTTSAKSCTGDGTAMVA........RAGLPAEDMEF...VQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTL.WTGEVISPRDGDDNAIVPG..LLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
..................................PKTLNQFRNFSYIVVAWLGFNKGFREKAANDAEWIAHQQRVRQQNVERHQAASAMMEA......................................................................................................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...........................................................................................VAPKTLNQFRNFSYIVVAWLGFNKGFREKAANDAEWIAHQQRVRQQNV..........................................................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMG...LPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................................................................................................................................................................................................................................................................................................................................................................................AFHDVSTDAIRQMQASEALQKHLENAQLAHRVCVAKALKAD...EPPVEKCALTWGEVVMRYNQWSEYRPAFHDSDAQKRYSKYWTKKRQA  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP............................................  
s1:
..........................................................................................................................................................................................SRVSNKISGGMACQTVVNHGYYLKPMTGNPYLCTQHDGVTTAYQQGFAPKDFNWLYRFRYNLLPQGMSGGFFSRNPYGRYVHWLEVSTIEKMRLQMFTMESVPCSVVSLILLVFTMWHSYRLAFLHPDITLYNLGLWSTKPWVQQQRFNKKKELDQDVYRWMTRVPEV..........MMDDPIREMYKMGIT.ANDPVYAMAKEQGVEHELTMTHAEYTSTSPDIRRVIANARK...............................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYT..ILCTGGYGRVYF...TTTSAKSCT.GDGTAMVARAGLPAEDMEFV.QFH....PTGI.........YGPGVLITERDVVS....RAITMEILKLPGISESAHIFA.....GVDVIVPTVH.YSMGGVPTL.WTGEV.ISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGE..ASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.................................................................................................................................................................................................................................KLYASDFERAQF.PANIV.PSDSVTFAKFLYKAV...........EPKGSFDAILKDFQTIAAAIPKLPIFWERTVVVSEVNEFKSL..........SAPTIFTLEWMQSNGMLDLLPDVAEVYETYVSAKMK..RVTAKIYVAPGK....EQDRALVDKARKVAEQVVKDNKQLAGYTLVPKVLVDRSIVEGFAVDVVNEAVG.....................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
......................................................................................................................................................................................SGRLRLYKEKLEGYNRFYSIVKTIKMVTMAKFRQAQVRIKTRDYTLRYTEKAF.SKPGQLVGDSPQAKAIYIP..VMTNRGSCG.ALNSNVVKVIDSVASSRAY.....LMPLGKRGIESLSKLYPS...SFRMGIVNDMHEPMHFA..YATYVWENAQQLCPEADRVHIIFHR.CVSA.......GSQKQCYYNIPAYEKWKEDLVDASSTENQKSRYLFANTLLNEDEQMIRDFYDFHATLAILNAVCENELSEQAARLVAVEGQLSNISTLQQKTSSLYNKTRQSSITSSLIEIISAMTSLEGNAAKGVQRTN..................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSK.......YTILCT.GGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTG..IYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGE...ASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSH...ALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDD..ANGTVRLAYRPVHMEMLTNELESIPP  
s1:
................................................................................................YTELSHMKFPVYYGAVGVVLGYFVVMWVVFLRMGSKHTARSEFKNDYLRVWRRRLGTGYEWADAWGPEMGT..FFKDLPEE.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFI..YQRAFGGQSIKQARRTCAASD......RTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...........................................................................................................................DMHSSDRFKAAWDE...IPLHMLGASHKQMFEWYWRAMYQLGL..RDPYRLTKLRSMLNWAALFSFMYLTYISIFYSSFYHVYMMDWPEHFKRENAREYALSHGHDVWAGDGKFIRPYFH...INPPMLTMTSEDI....................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFK.SKYTILCTGGYGRVYFTTTSA..KSCTGDGTAMVARAGLPAEDMEFVQ..FHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...........................................................................................................................................................................................................................................................................................................................TYFYANCGETGISGATMQVLLKLTLACCVVQVFAIRYFVFQRLTTKKQFVEDSTDLWESDGTEMD......GEEAVANLRIQHERIMPFMNDIKDKLDAQ......................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGAN.RLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALY..AEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
TMNFGNMTLGGAMATFGGQSNPMCNYTSPLAKKFVYKEVGKVHYPLRRHVFRTKVRTAAEIRFNEIVKRYMKEKMT.FKRGCYAATI...TNTVELDH.MGSIIPKDEYEVKRLTSYMTSKKMS....SDYKKHMQELWTRVLFVCESTNL..VGVTENAMHQNSRPGTDEEFMSIIWYSSFVTTLMAFVVTLFIWWYRYGQAPQYAEF.................................................................................................................................................................................................................................................................................................................................................  
s2:
..........................................AYPVIDHTYDCVVVGAG....GSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASD.RTGHAMLHTLYGQSFQYG.VNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.................................................................................................................................................................................................................................ELP.EAFEFIE.HK.........VTDKDIHSAYENMETLRLTVTRQDEFLFKETPVKCVTI.VGVNGENGVYPGHAYEITQLTPAPLTVEMPDGTVKKFFTSGGFAHINNEGSCDI.....NCVECI.........PLAELDLDAAEKALAQQQSALSSAHD.......EKAKAVIEIRIGVLESVIQSLKHMKE.................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMAL...YAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
......................................................................................................................................................................................................................................................PLATLKPVLAESVATQNVIRRMIGVTTNRKVNASAINSVAEKTKGEGLAGTTAVVARAHLYLLSRNPTDAVAEIDAVLPKVQDEALRRFAIGIRLRSHNELLDMKEASLGVSG..................GATESEVSDLRSKLQ.KDYKELVTSSPGCWLVELAAAEYTLYTG..ASEEAYKSFSSIEKKIQEYIKAPIHVSELVATADNTNEFSLIGFQVRRARPGVKPEGVSASVAEGMANVMADPAAVKALQQAKKAFEEALELVVTLQEANVGHHFHDFFPTTPDHYDKWTSEAARSAQQLIQEALTPHSVGLKPEAIDRIRVSMTNKAFYDSEEKLHALLKSAPKDKSIIASIRETFGPGPSTPISSSDQAVADAVESVHLAVVSSDTAGATDYAKRGKEIAKALAKQLLYRTQVQKCVALTEMNCLQEAVDVVTPVIDANEYIYMWRAFLARSRAYKGLGLITNADKDLKELNRLKHSLTERTPYEKK  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITME..ILKLPGISESAHIFAGV..DVIVPTVHYSMGGVPTLWTGE...VISPRDGDDNAIVPGLL..AAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSH....ALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP.......................................................................................................................................................................................................................................  
s1:
.............................................................................................................................................................................................MFWLCLVCLSVSHKMIGLCYLLVAILSGFVGYVYSLFIRLELSLIGCGIL....FGDYQFYNVLITSHGLIMVFAFIMPVMMGGLVNYFIPVMAGFPDMVFPRLNNMSFWMYLAGFGCVVNGFLTEEGMGVGWTLYPTLICIDFHSSLACDFVMFAVHLLGISSILNSINLLGTL.....FCCRRKFFSFLSWSLFIWAALITAILLIITLPVLAGGVTLILCDRNFNTSF..Y..DVVGGGDLILFQHIFWFFGHPEVYIILLPVFGLISTIVEVIGFRCVFSTVAMIYSMILIAILGMFVWAHHM.FVVGMDVDSRAYFGGVSILIGLPTCVKLFNWIYSFLYTDMIITFEVYFVIMFIFMFLIGAVTGLFLSNVGIDIMLHDTYFVVGHFHYVLSLGAVVGFFTGFIHFLAKWLPIELYLFWMFYFISTLFIGSNMLFFPMHSLGMYAFPRRISDYPVSFLFWSSFMLYGMLLLASLILFLCALFCVFLFWDYCLFFVSLFVFSLYCFFYFSTWLPCVMVLYLLLVDFAHIVLDYLFLILCFCFVFFIFFWQSLFLFFYI  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTG....GYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYG.PGVLITERDVVS.RAITMEILKLPGISESAHIFAGV.DVIVPTVH.....YSMGGVPTLWTGEVISPRDGDDNAIVPGLLAA...GECACASV.HGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILN...NKGDIPIARIRERMKETMALYAEDSMQTG.KNIIEECYRDFSHALVHD.KSPVWN..SNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP.......................................................................................................................................................................................................................................  
s1:
................................................................................................................................................................................................................................................................................................................................................................................................................................ASCR...TGRLPMPDDPLFNSTHMHGLRHSSRIAGLGMIAVIWIMYEKLRHSHHYITYKGPENPFARIRHRRFPGGAFMFGWGNNGLNRDCGIKEFECWAGYTGKEYTYV  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMK.....HTLTYLDDANGTVRLAYR..PVHMEMLTNELESIPP.....................  
s1:
VAKISSIERASTYLRFSTLRVHPHHEPNFRARPVGWKAWNSKQYMDPWAPYPL...TSPVRHVDRPFSGMWFGMGHFALKNFFGPLNWKFWARVSFFGTLGWAYSLSSYALRMHRNGWEWKNRGAVF.......................................................................................................................................................................................................................................................................................................................................................................................................................................  
s2:
.................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQG...GINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
..................................................................................................KVLIADLPMMWPSDMRRFEKEGGVWGQQFRQRRRQLTFALTISAASTLLGSWYVVMRRRN.TYFVLFSTFSGFSVLGFCIGMSLAPLWYENVANNK......ETSMMRRVWWAKECAKHWD...........................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG..GQSIKQARR..TCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
TPYQDKSYPVQPHNLDELQQPPDSWRKSPIMSKLMDQSLPVYDDVVTGVGRLYWQEPARVWHLFEADDTLMLEEHDREEWNDRPYVAVNHLYEPPIGSEERPIRVEGTGNPGDQQIVLCFGNCAPHVPQSNYYMMMKGYNKTKCPMCQQWFYIHNRPWLVMHPDWT.DEPAAD...EGPAYTFSEIEA...EFDRDFHEFGVYLNAE..........................................................................................................................................................................................................................................................................................................................................................................................  
s2:
...................................................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKL...YPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGF.IYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.........................................................................................................................................................................................................................................................AEARAVLQAQSHRTVSAVVPGKMFMRHWIVAEQSTVSVVNRVISGMVAVFTMIWAAGYATLGYNGHNSAHVAGWIFIAYWVVLHTH.IMWLAPTML................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILK..LPGISESAHIFAGVDVIVPTVHYSMGGVPTLWT.....GEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
..........................................................................................................................................................................................................................................................................PG..QLANYSSPLYMYSHLIKNSTAKTPQLYTA.....KDNSKTAM.HLLTRRGATANYTVNRWYLKEKVDSSNRMRLEGLYECVLCASCTGSCPQYWWNREHFLGPAVLLQSYRWLVEPLDR...............DFDERVRMF.....ETG.TLVNMCHNIFNCSIT...CPKFLNPGLASKEIKRLSSPAAKRVGPAIE.....................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVH.........GANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...............................................................................................................................................................................................................................................................................................................................................EDHRKYKVQREELPRMPHFNDFNDPRFCGTTNKQKNGILAYYQWLHCIGNWGE......EHSMCKKMRWYVERMMHETWLEKWEEKRALGHFDHTILYGVKP.WK.......EFEPLYQPVKKNRKGAYEYWLDRDFEPLYDADAADWREKAPILHDMFVLGKKPVA.  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPEL.RADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQ...TGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVR.MKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.............................................................................................................................................................................................................................................................................................................................................................WPSKLPLTKNWYYHLS.RRD....SIADETRQYMVVGDFLLLFVVSFSMYRLYVLNRNNTYQTHLSHLI.....NYPPAIIANEFDFKDSNANRLVERKDLDAYREDVVRCRAS.....................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGD.IPIARIRERMKETMALYAEDSMQTG.KNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
....................................................................................................................................................................................................................................................................................YGHALELDTHNYKFNGEPPSWMKTHAKTEEETSFAKSVLPHIDFASSYECL.LFDADRLNTN......LNRKEFGNEIKYRLEKQANTVARAQQLLKDKKAGTGPDAAKIENTLIARIFDEEHVQAEMKYVKCIRANELAEDNRLDI...LPGGSPNSLREKTR.WNLN....TELHPADRAEIGARLTAWLPEKYHIVYFDDFQTVA..ANDATARREMLEIVESVQKEYTAEAKEGGYESDLKETVAELMDDVDPTRAITMEAIKSCKDLQQLEDWSRQVHEYNGDDRIIEIYARAAEITKNAEHQALVKQMREWRKLATK  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLW..TGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGR...KQPELRADAGEASIADLDRILNN..KGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP..............................................................................................  
s1:
.............................................................................................................................................................................................................................................................................................................................................................................................................SLSTILYSPIGTSMMIMLAYNVIVICSKHVNYSLEITAKDYVQDQQLLTIMRYGILSCILLGMEVMFIEIG..................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAE..DSM..QTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
............................................................................................................................................................................................................................................PRPFGVWAPATTLAEYRA..........RIP..NPFAYSFKWVYSMKREVFY.....PPEALAHFKDPQQFKDAVDTVIAMRVSD....KIFGEGQKLPRHPVILMLMVLATHGFIIFSGLKYYYGTYMPANNPTWRKTVNKEWEEAINNSPWDHMSHVWQYSDEYAAALGDTAAPGQRKFYIPA...............................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKE..GRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
........................PATVKRPLWSLLLPQTYTSRIHTLAFHAPSILFMIAVCAIISKQSYYRSSLADEDPKTYDRIDRRAYVALPDGRMALVYPIIDTQTSFTRTVISFLDAVNPF..........................................................................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQG.GINAALANC....EEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQ.RAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.............................................................................................................................................................................................................................................................................................IYTTWGSVPCEDWARNESWLKRITSQSDYRSFEFWHVPQADVPAGLRLNAVERYLLSSLENDTDRLLHVSWCEDFDPYWHDRVGSLEMLYKI....VYTNDYPLYRYIFGNC.MHKVAEKEYMLRKLNYLKSVLFWAGRTERCYTSIVKARYYVQRCVWNALERERYLCACVEAVDSFGKKVPEELRQKVMPELEVALVSMRHWV..WDCPNGKRTFTRRLA..................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPT.......LWTGEVISPRDGDDNAI..VPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWN..............SNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANG....TVRLAYRPVHMEMLTNELESIPP  
s1:
.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SLADKIVRGPPKSVYYTHPRYVMSRDKMLHTIWVDIGIFQTCAYALFPFFSAAYFFK  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP..............................................  
s1:
................................................................................................................................................................................................................................................................................TYMLAFNSKAKARPNFGLRGV.GYWTSEVYHK.........PGQNYWMVVCCAGPFLLVGAIMMDGFWSKLDDIAGGGPSA..LDYGWRSQDRKPWDFSFDIGEGYAAGPAVYRPASGAVDL............................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACAS...VHGANRL.GANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
................................................................................................................................................................KAVLQLVRFDPETNSSRVESYEYDKHHEYMVLDLLIAVKAHQDPTLAFRSSCCEGVCGS.CAMNINGINSLACITFAQHVTTVAPLPNFPVIKDFVVDLRHFFQQYAYIRPYVRNANLHRSQVDGIVERYNTVARVLSGVSPSEGRAMEKAQEELRETTVAALLRIADAAVDAGNATQALSVLEKVEQQ..GVVLDSTRVTEMIERALKNFAAKS..................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGY..GRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVS.RAITMEILKLPGISESAHIFAG.VDVIVP...TVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
................................................................................................................................................................YETFTPKTLSG..RLVMPGNINLLTVSPLYCAVLCIAAATWGVFYWDIYCRKNYE...TVLIARP....KDM..........................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
MFVRVIFVGVSGVFVFLSLPAICIVYLTFCLCGLFCIMFGSFIFIDYCFICFFACLLFCLVCLLCDLFVDSLRGLFDVCCFIRCIQYCFVWFIISELLLFLSLFYVVFSLVLFVSVEFAFVFVIPVMFSCLICDFGFVFYWYFIDIFNLLINTFLLFVSGLFVNFVLFLFWFRFFLCVLFMLWVGILFGFLFLWNQVWEFALLFVTCSCGVFGSILFLIDLLHFSHVFLGIFLLFLCFSRCFNFLCMDTRFVFLYVVCLYWHFVDCVWFFLLRFVYFDVLSVV......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................  
s2:
...............................................................................................................................................................................................................................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...............................................MFLGGFVPRRFTQLNRD..PWWMFFIFSVGAWIGEYPAMQIKYNARDLV...LDPHRYVWSHLDDHH................................................................................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
............................................................................................................................MGHEETTFSRGNRTRNNALQHIYGLMGLCGVGCVLALFSFVSGQRRIQTTITADGTMTKGTCPT...............................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGV.......NFYN.EYYCLDLITEDG.CCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
......................................................................................................................................................MAFILSFWMIFLLDSVIVLLSFVCFVCVWICALLFSTVLLVSKLNNIYCTWDFTASKFIDVYWFTIGGMFSLGLLLRLCLLLYFGHLNFVSFDLCKVVGFQWYWVYFIFGETTIFSNLILESDYMIGDLRLLQCNHVLTLLSLVIYKLWLSAVDVIHSFAISSLGVKVDCIPGRCNEIVLFSSNNATVYGQCSELCGVLHGFMPIVICFI................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLIT..EDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTT...SAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGI.....YGPGVLITERDVVSRAITME..ILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWT....GEVISPRDGDDNAIV....PGLLAAGECA..CASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
......................................................................................................................................................................YTRWKCDR......IPVLQLKLFTQEYNIMALVGLLSMVFLFKHASYCSEETERKNGWWAGYP........YWRDPIARRNEIRYKQLINSNDVDITDPKWTGCSKEQ.................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVA.RAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
................................................................................................................................................................................................................................................................................TYMLAFNSKAKARPNFGLRGV.GYWTSEVYH.KPGQNYWMV..VCCAGPFL...LVGAIMMDGFWSKLDDIAGGGPSA..LDYGWRSQDRKPWDFSFDIGEGYAAGPAVYRPASGAVDL............................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRL.GANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
..............................................................................................................................................................................................................................................................................................................................TMNFGNMTLGGAMATFGGQSNPMCNYTSPLAKKFVYK..EVGKVHYPLRRHVFRTKVRTAAEIRFN......EIVKRYMKEKMTFKRGCYAATITNTVE.........LDHMGS.IIPKDEYEVKRLTSYMTSKKMS.SDYKKHMQELWTRVLFVCESTNLVGVTENAMHQNSRPGTDEEFMSIIWYSSFVTTLMAFVVTLFIWWYRYGQAPQYAEF  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLT...YLDDANGTVRLAYRPVHMEMLTNELESIPP..................................  
s1:
....................................................................................................................................................................................................................................................................................YGHALELDTHNYKFNGEPPSWMKTHAKTEEETSFAKSVLPHIDFASSYECLLF.DADRLNTN......LNRKEFGNEIKYRLEKQANTVARAQQLLKDKKAGTGPDAAKIENTLIARIFDEEHVQAEMKYVKCIRANELAEDNRLDILPGGSPNSLREKTRWNLNTELHPADRAEIGARLTAWLPEKYHIVYFDDFQTVAANDATARREMLEIVESVQKEYTAEAKEGGYESDLKETVAELMDDVDPTRAITMEAIKSCKDLQQLEDWSRQVHEYNGDDRIIEIYARAAEITKNAEHQALVKQMREWRKLATK  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLW..TGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGR...KQPELRADAGEASIADLDRILNN..KGDIPIARIRERMKETMAL....YAEDS....MQTG.KNIIEECYRDFSHALVH..DKSPV......WNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRL.AYRPVHMEMLTNELESIPP..................................................................  
s1:
......................................................................................................................................................................................................................................................................................................................................................FFGKGWDNAALDTIFSSMLRKPEVNDRIRTQYASTMD...PRDADVLRRLGEVSKENKTFIRVFLPPHL.GDPHRLLKCYSLMAYPILDDKGGQLKVEM.DGCKL.DAFADPDDDYSKVVIPHIELVEYLAKSLLETMKWEATPRGAASLLESLYRGAEIPDHVFQTPAVIERLEDYKDGNKVIS  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDI..PIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDAN.GTVRLAYRPVHMEMLTNEL...ESIPP.......................  
s1:
.....................................................................................LHFPLSPPPIEIDYLDSDPLEFAVRTEARRWGFDDLQYMRELAFVRIKENPSIGDFRRMTPEERRDLFWGSD....RQDFFRYITLKLTGHPEHLYHRGW..................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPF.LRTK......DGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLI..TEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
TPYQDKSYPVQPHNLDELQQPPDSWRKSPIMSKLMDQSLPVYDDVVTGVGRLYWQEPARVWHLFEADDTLMLEEHDREEWNDRPYVAVNHLYE.PPIGSEERPIRVE.GTGNPGDQQIVLCFGNCAPHVPQSNYYMMMKGYNKTKCPMCQQWFYIHNRPWLVMHPDWT.DEPA....ADEGPAYT..FSEIEAEFDRDFHEFGVYLNAE..........................................................................................................................................................................................................................................................................................................................................................................................  
s2:
...................................................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYD..VACISKL...YPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGF.IYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.............................................................................................................................................................................................MFWLCLVCLSVSHKMIGLCYLLVAILSGFVGYVYSLFIRLELSLIGCGIL....FGDYQFYNVLITSHGLIMVFAFIMPVMMGGLVNYFIPVMAGFPDMVFPRLNNMSFWMYLAGFGCVVNGFLTEEGMGVGWTLYPTLICIDFHSSLACDFVMFAVHLLGISSILNSINLLGTLFCC.....RRKFFSFLSWSLFIWAALITAILLIITLPVLAGGVTLILCDRNFNTSF..Y..DVVGGGDLILFQHIFWFFGHPEVYIILLPVFGLISTIVEVIGFRCVFSTVAMIYSMILIAILGMFVWAHHM.FVVGMDVDSRAYFGGVSILIGLPTCVKLFNWIYSFLYTDMIITFEVYFVIMFIFMFLIGAVTGLFLSNVGIDIMLHDTYFVVGHFHYVLSLGAVVGFFTGFIHFLAKWLPIELYLFWMFYFISTLFIGSNMLFFPMHSLGMYAFPRRISDYPVSFLFWSSFMLYGMLLLASLILFLCALFCVFLFWDYCLFFVSLFVFSLYCFFYFSTWLPCVMVLYLLLVDFAHIVLDYLFLILCFCFVFFIFFWQSLFLFFYI  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTG....GYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYG.PGVLITERDVVS.RAITMEILKLPGISESAHIFAGV.DVIVPTVH.....YSMGGVPTLWTGEVISPRDGDDNAIVPGLLAA...GECACASV.HGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNN...KGDIPIARIRERMKETMALYAEDSMQTG.KNIIEECYRDFSHALVHD.KSPVWN..SNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP.......................................................................................................................................................................................................................................  
s1:
MFVRVIFVGVSGVFVFLSLPAICIVYLTFCLCGLFCIMFGSFIFIDYCFICFFACLLFCLVCLLCDLFVDSLRGLFDVCCFIRCIQYCFVWFIISELLLFLSLFYVVFSLVLFVSVEFAFVFVIPVMFSCLICDFGFVFYWYFIDIFNLLINTFLLFVSGLFVNFVLFLFWFRFFLCVLFMLWVGILFGFLFLWNQVWEFALLFVTCSCGVFGSILFLIDLLHFSHVFLGIFLLFLCFSRCFNFLCMDTRFVFLYVVCLYWHFVDCVWFFLLRFVYFDVLSVV......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................  
s2:
...............................................................................................................................................................................................................................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
VAKISSIERASTYLRFSTLRVHPHHEPNFRARPVGWKAWNSKQYMDPWAPYPL...TSPVRHVDRPFSGMWFGMGHFALKNFFGPLNWKFWARVSFFGTLGWAYSLSSYALRMHRNGWEWKNRGAVF.......................................................................................................................................................................................................................................................................................................................................................................................................................................  
s2:
.................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQG...GINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...........................................................................................................................DMHSSDRFKAAWDE...IPLHMLGASHKQMFEWYWRAMYQLGL..RDPYRLTKLRSMLNWAALFSFMYLTYISIFYSSFYHVYMMDWPEHFKRENAREYALSHGHDVWAGDGKFIRPYFH...INPPMLTMTSEDI....................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFK.SKYTILCTGGYGRVYFTTTSA..KSCTGDGTAMVARAGLPAEDMEFVQ..FHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
......................................................................................................................................................MAFILSFWMIFLLDSVIVLLSFVCFVCVWICALLFSTVLLVSKLNNIYCTWDFTASKFIDVYWFTIGGMFSLGLLLRLCLLLYFGHLNFVSFDLCKVVGFQWYWVYFIFGETTIFSNLILESDYMIGDLRLLQCNHVLTLLSLVIYKLWLSAVDVIHSFAISSLGVKVDCIPGRCNEIVLFSSNNATVYGQCSELCGVLHGFMPIVICFI................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLIT..EDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTT...SAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGI.....YGPGVLITERDVVSRAITME..ILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWT....GEVISPRDGDDNAIV....PGLLAAGECA..CASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
..........................................................................................................................................................................................SRVSNKISGGMACQTVVNHGYYLKPMTGNPYLCTQHDGVTTAYQQGFAPKDFNWLYRFRYNLLPQGMSGGFFSRNPYGRYVHWLEVSTIEKMRLQMFTMESVPCSVVSLILLVFTMWHSYRLAFLHPDITLYNLGLWSTKPWVQQQRFNKKKELDQDVYRWMTRVPEV..........MMDDPIREMYKMGIT.ANDPVYAMAKEQGVEHELTMTHAEYTSTSPDIRRVIANARK...............................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYT..ILCTGGYGRVYF...TTTSAKSCT.GDGTAMVARAGLPAEDMEFV.QFH....PTGI.........YGPGVLITERDVVS....RAITMEILKLPGISESAHIFA.....GVDVIVPTVH.YSMGGVPTL.WTGEV.ISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGE..ASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...........................................................................................................................................................................................................................................................................................................................TYFYANCGETGISGATMQVLLKLTLACCVVQVFAIRYFVFQRLTTKKQFVEDSTDLWESDGTEMD......GEEAVANLRIQHERIMPFMNDIKDKLDAQ......................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGAN.RLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALY..AEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
................................................................................................YTELSHMKFPVYYGAVGVVLGYFVVMWVVFLRMGSKHTARSEFKNDYLRVWRRRLGTGYEWADAWGPEMGT..FFKDLPEE.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFI..YQRAFGGQSIKQARRTCAASD......RTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
EDHRKYKVQREELPRMPHFNDFNDPRFCGTTNKQKNGILAYYQWLHCIGNW..GEEHSMCKKMRWYVERMMHETWLEKWEEKRALGHFDHT.....ILYGVK..PW..KEFEPLYQPVKKNRKG.AYEYWLD.RDFEPLYDADAADWREKAPILHDMFVLGKKPVA.......................................................................................................................................................................................................................................................................................................................................................  
s2:
...........AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
................................................................................................................................................................................................................................................................................................................................................................................................................................ASCR...TGRLPMPDDPLFNSTHMHGLRHSSRIAGLGMIAVIWIMYEKLRHSHHYITYKGPENPFARIRHRRFPGGAFMFGWGNNGLNRDCGIKEFECWAGYTGKEYTYV  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMK.....HTLTYLDDANGTVRLAYR..PVHMEMLTNELESIPP.....................  
s1:
............................................................................................................................................................................................................................................PRPFGVWAPATTLAEYRAR..........IP..NPFAYSFKWVYSMKREVFY.....PPEALAHFKDPQQFKDAVDTVIAMRVSD....KIFGEGQKLPRHPVILMLMVLATHGFIIFSGLKYYYGTYMPANNPTWRKTVNKEWEEAINNSPWDHMSHVWQYSDEYAAALGDTAAPGQRKFYIPA...............................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKE..GRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
........................................................................................................................................................................................................................................................MLRRHAYKTAACVTAIQ...VARAVHSIAVLQNSTPATTAQKLGSVVSKEEVAAVNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLIAT..ITD.EVDYTSIEQQVAKRFSKDPSKLQPTPGALKHFRENNWKDMKSLITFYEETMYPIRMKHKEYKYHELTSFHIKDVLKRGLSAFKQSYLDEQREEQTKVKAYMKSCDDFVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNL.MRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVGTASLENISDEVLKLISNRHQTPLDDGVLIRSPDTHPNLQRSPE  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVP.TVHYSMGGVPTLWTGEVIS..PRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRK.QPELRA..DAGEASIADLDRILNNKGD....IPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSH.ALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRM.........KHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP.................................................................  
s1:
MLRRTFTRLALSRAYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIHYGGKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITEGARGEGGYLVNSEGERFMERYAPKAKDLASRDVVSRAITMEILAGRGCGPKKDHVMLQLHHLDPATLHKKLPGISESAHIFAGVDVTKEPIPIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAAVFRTEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRKESRGAHARDDYQERDDHNWMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPPAKRVY  
s2:
.............AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSI....KQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITE..............................RDVVSRAITMEIL..........................KLPGISESAHIFAGVDV......IVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYA.....EDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVR....................MKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP.....  

> matchmaker #9/K5 to #1.2/K5

Computing secondary structure  
Parameters  
---  
Chain pairing | bb  
Alignment algorithm | Needleman-Wunsch  
Similarity matrix | BLOSUM-62  
SS fraction | 0.3  
Gap open (HH/SS/other) | 18/18/6  
Gap extend | 1  
SS matrix |  |  | H | S | O  
---|---|---|---  
H | 6 | -9 | -6  
S |  | 6 | -6  
O |  |  | 4  
Iteration cutoff | 2  
  
Matchmaker combination, chain K5 (#1.2) with chainK5.cif, chain K5 (#9),
sequence alignment score = 2215.7  
RMSD between 387 pruned atom pairs is 1.201 angstroms; (across all 498 pairs:
2.475)  
  
Computing secondary structure  
s1:
............................................................................................................................................................................................................................................................................ASKEEQIKKNTKIAIEMIRRYKGETPMSYTRKHTATIEQLEREIEALLGGAQKMRKATTD.......DQPMDKLGLMERCLRHALWSYHKDEGKYDFDEIARWVVYTPEDEVKLAQMKRQVEAKSKLAAYRAKRAEQ......GLPEAPVPQISWEEEYKNVTDRELVNEKRLRYDTIAANTMERDEAQIEAVLQQYRKPIQDKRLDDLVDLLERFKPVLAREAIMQRLTIKHLEGQLGVWRYMDWCPEVRDRAELEVDISGFQWWSPLEERRLLPVRLRSVNEVREIMAQTQSSKAAEASAHSPQASQSAGDGDRERLLKEVLALQARIHQRDDAP  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQ..PELR.....ADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSH.ALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLT.NELESIPP..................................................................................................  
s1:
.......................................................................................................................................................................................PAEHKGRVGYVSQVIGAVVDVHFS.........EGVPPVLTALDVTEDLG..RDEPLTLE....IVQHLDANTGRCIAMQTTDLLKL.KSKVVSTGGNISVPVGRETLGRIFNV.LGDAIDQRG...........PVGEKMRMAIHAEAPKLADQAAEDTILTTGIKVIDLILPYCKGG..KIGLFGGAGVGKTVIIMELINNVAKGHGGFSVFAGVGERTREGTDLYLEMMQSKVIDLKGDSKCVLVYGQMNEPPGARARVAQSALTMAEYFRDVEGQNVLLFIDNIFRFTQANSEVSALLGRIPAAVGYQPTLAEDLGMLQERITSTTKGSITSVQAVYVPADDITDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMDPDVIDVNHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQVAEVFTGMTGHYVQLNDTVESFSGLLMGSYDQIPEMAFYMVGGINSVLEKAKAMAEEAAAMEK  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDV.VSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHG.ANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNN..KGD...IPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHD....KSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLA..YRPVHMEMLTNELESIPP........................................................................................................................................................................................  
s1:
......................................................................................................................................................................................................................................................................................................................................................FFGKGWDNAALDTIFSSMLRKPEVNDRIRTQYASTMD...PRDADVLRRLGEVSKENKTFIRVFLPPHL.GDPHRLLKCYSLMAYPILDDKGGQLKVEM.DGCKLD.AFADPDDDYSKVVIPHIELVEYLAKSLLETMKWEATPRGAASLLESLYRGAEIPDHVFQTPAVIERLEDYKDGNKVIS  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDI..PIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYL.DDANGTVRLAYRPVHMEMLTNEL...ESIPP.......................  
s1:
..........................................................................................................................................................................................................KATEMIGYVHSIDGTIATLIPAPGNPGVAYNTIIMIQVSPTTFAAGLVFNLEKDGRIGIILMD..NITEVQSGQKVMATGKLLYIPV......GAGVL..GKVVNPLGHE....VPVGLQTLGKVDAGAPNIVSRSPVNYNL...LTGFKAVDTMI....PIGRGQRELIVGDRQTGKTSIAVSTIINQVRNNQQIL....SKNAVISIYVSIGQRCSNVARIHRLLRSYG.ALRY..TTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDD.LSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNVAMKAVAGKLKGILAEYRKLAADQVQTVPMIRGARFVALFNQKNPSFFMNALVSLYACLNGYLDDVKVNYAKLYEYLLVNKDLSVMYGTATNKFFYMYVQQLNYVIRFFTLNHPILNAEVEEMLKQHTHLFLQHYQSKMNAIKTEKEIKALKNLLYSCKRAV  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPA...EDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFA.GVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVP.GLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPEL...RADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQ.TGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVV.RMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP.......................................................................................................................................................................................................................................................  
s1:
.........................................................................................................................................................................................EHKGRVGYVSQVIGAVVDVHFS.........EGVPPVLTALDVTEDLGRDEPLTLEIVQHLDANTGRCIAMQ..TTDLLKL....KSKVVSTGGNISVPVGRETLGRIFNV.LGDAIDQRG...........PVGEKMRMAIHAEAPKLADQAAEDTILTTGIKVIDLILPYCKGG..KIGLFGGAGVGKTVIIMELINNVAKGHGGFSVFAGVGERTREGTDLYLEMMQSKVIDLKGDSKCVLVYGQMNEPPGARARVAQSALTMAEYFRDVEGQNVLLFIDNIFRFTQANSEVSALLGRIPAAVGYQPTLAEDLGMLQERITSTTKGSITSVQAVYVTDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMDPDVIDVNHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQVAEVFTGMTGHYVQLNDTVESFSGLLMGSYDQIPEMAFYMVGGINSVLEKAKAMAEEAAAMEKQRRAR  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHG.ANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNN..KGD...IPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHD....KSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLA..YRPVHMEMLTNELESIPP........................................................................................................................................................................................  
s1:
........................................................................................................................................................................................................KGRVGYVSQVIGAVVDVHFSEGVPPVLTALDVTEDLGRDEPLTLEIVQHLDANTGRCIAMQ..TTDLLKL....KSKVVSTGGNISVPVGRETLGRIFNV.LGDAIDQRG...........PVGEKMRMAIHAEAPKLADQAAEDTILTTGIKVIDLILPYCKGGKI..GLFGGAGVGKTVIIMELINNVAKGHGGFSVFAGVGERTREGTDLYLEMMQSKVIDLKGDSKCVLVYGQMNEPPGARARVAQSALTMAEYFRDVEGQNVLLFIDNIFRFTQANSEVSALLGRIPAAVGYQPTLAEDLGMLQERITSTTKGSITSVQAVYVPADDITDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMDPDVIDVNHYNVAQDIVQMLTKYKELQDIIAVLGIDELSEEDKVVVDRARKVTRFLSQPFQVAEVFTGMTGHYVQLNDTVESFSGLLMGSYDQIPEMAFYMVGGINSVLEKAKAMAEEAAAMEENKAAH  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCT....GDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHG.ANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNN..KGD...IPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHD....KSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLA..YRPVHMEMLTNELESIPP.............................................................................................................................................................................................  
s1:
KYDLFGYEVDTNTAPWIEKVKKCR.YYDEAGEVLVSMNVKNCPPDLETYNATLQKIFEAPSKQEKPVENESKFCAMMDLMEEMQHRNKVKPNEESWTWVMKECVQSGQFRLGYCVAKLMEAEF.............KRVPEDLVKQNEANAAKAKADGKEHPSTLAQQQSLFDIKIQ....................................................................................................................................................................................................................................................................................................................................................  
s2:
............AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDV....ACISKLY..PSRS.HTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.....................................................................................LHFPLSPPPIEIDYLDSDPLEFAVRTEARRWGFDDLQYMRELAFVRIKENPSIGDFRRMTPEERRDLFWGSD....RQDFFRYITLKLTGHPEHLYHRGW..................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPF.LRTK......DGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLI..TEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
....................................................................................................................................................................................................................................ASDLKMVSLHKILI...GEVQFRNNALLKACNIEHNFGPTWKSEIEAYA...KSLPAEEKNCLERQIARVSMTRYTTRELAEYCGEGPEHVDAVAREANIAQAKVYAQKNGADKLETYVKAEAKNAGWSEAETKKFMDAVKAAK........................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPT.....VHYSMGGVP.TLWTGEVISPRDGDDNAIVPGLLAAGECACASVH....GANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
AKKYDLFGYEVDTNTAPWIEKVKKCR.YYDEAGEVLVSMNVKNCPPDLETYNATLQKIFEAPSKQEKPVENESKFCAMMDLMEEMQHRNKVKPNEESWTWVMKECVQSGQFRLGYCVAKLMEAEF.............KRVPEDLVKQNEANAAKAKADGKEHPSTLAQQQSLFDIKIQ....................................................................................................................................................................................................................................................................................................................................................  
s2:
..............AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDV....ACISKLY..PSRS.HTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.....................................................................................................................................................................................................TEMIGYVH.......SIDGTIATLIPAPGNPGVAYNTIIMIQVSPTTFAAGLVFNLEKDGRIGIILMD..NITEVQSGQKVMATGKLLYIPV......GAGVL..GKVVNPLGHE....VPVGQTLGKVDAGAPNIVSRSPVNYNL...LTGFKAVDTMI....PIGRGQRELIVGDRQTGKTSIAVSTIINQVRNNQQIL....SKNAVISIYVSIGQRCSNVARIHRLLRSYG.ALRY..TTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDDL.SKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNVAMKAVAGKLKGILAEYRKLAADVQTVPMIRGARFVALFNQKNPSFFMNALVSLYACLNGYLDDVKVNYAKLYEYLLVNKDLSVMYGTATNKFFYMYVQQLNYVIRFFTLNHPILNAEVEEMLKQHTHLFLQHYQSKMNAIKTEKEIKALKNLLYSCKRAV  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPA...EDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFA.GVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPEL...RADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQ.TGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVV.RMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP......................................................................................................................................................................................................................................................  
s1:
GAKKYDLFGYEVDTNTAPWIEKVKKCRYYDEAGEVLVSMN.VKNCPPDLETYNATLQKIFEAPSKQEKPVENESKFCAMMDLMEEMQHRNKVKPNEESWTWVMKECVQSGQFRLGYCVAKLMEAE...FKRVPEDLVKQNEANAAKAKADGK....EHPSTLAQQQSLFDIKIQ..........................................................................................................................................................................................................................................................................................................................................................  
s2:
...............AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDV....ACISKLY..PSRS.HTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
..........................................................................................................................................................................................................................SIAVIAAGAPAALLQAVSSILSKATGGAVKATQATSAASNAVVV......GMQAPRGVYACVAEPPSTASGPYAGVKTV.VVRAILPRSAPDT......................MQVRDILDVYPASGIACEKETAEAVKNFTKAAKVAVEKAKAMKATRVTLVM.KPATKYERLNGLFRETCTKTIEAA...GLSVETSTTAAATNTLI..MFPEKMSVVMVSDD..PVCENVQYAYAGAVGGV.HTTYYTDSGNKIYGGHSYRSVAM.ALAEELKSLGMKAEAAKVEAAVQKSPRNAAAAM  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITE.RDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTV.RLAYRPVHMEMLTNELESIPP......................  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
....................................................................................................SIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................ISIQGLHYVGTGLGAIALGGVGMGIGTIFGCLLIACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG...GQSIKQARRTCAAS.DRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.........................................................................................................................................................................................................................YTPSEELKKLYASDFERAQF.PANIV.PSDSVTFAKFLYKAV...........EPKGSFDAILKDFQTIAAAIPKLPIFWERTVVVSEVNEFKSL..........SAPTIFTLEWMQSNGMLDLLPDVAEVYETYV......SAKMKRVTAKIYVAPGKEQDRALVDKARKVAEQVVKDNKQLAGYTLVPKVLVDRSIVEGFAVDVQGTYVNEAVGRKIETEVLRKYLDSLSLY.DAEELKSGV.......................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDK..SPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
..............................................................................................................................................................................................................................................................................................................................................................................................................................................VALNWRDHGISYVKYLNVATEALHMATKDKARAKYSRFSTPNYIALVKKVPAFT................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRL..AYRPVHMEMLTNELESIPP  
s1:
............................................................................................................................................................................................................FFKATEMIGYVHSIDGTIATLIPAPGNPGVAYNTIIMIQVSPTTFAAGLVFNLEKDGRIGIILMD..NITEVQSGQKVMATGKLLYIPV......GAGVL..GKVVNPLGHE....VPVGLQTLGKVDAGAPNIVSRSPVNYNL...LTGFKAVDTMI....PIGRGQRELIVGDRQTGKTSIAVSTIINQVRNNQQIL....SKNAVISIYVSIGQRCSNVARIHRLLRSYG.ALRY..TTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDD.LSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNVAMKAVAGKLKGILAEYRKLAAQTVPMIRGARFVALFNQKNPSFFMNALVSLYACLNGYLDDVKVNYAKLYEYLLVNKDLSVMYGTATNKFFYMYVQQLNYVIRFFTLNHPILNAEVEEMLKQHTHLFLQHYQSKMNAIKTEKEIKALKNLLYSCKRAVG  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTS....AKSCTGDGTAMVARAGLPA...EDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFA.GVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVP.GLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPEL...RADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQ.TGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVV.RMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP.....................................................................................................................................................................................................................................................  
s1:
..............................................................................................................................................................................LSLLLCVHFSAIHRPPPPVPFTALAAFLYALT.LTAPVAEQRSGSSLHPQIEVGTEIEDMALFHLVVLPLVFFAAMCIGRG.....................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKS..KYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...............................................................................................................................................................................................................................................................................QMKVELTMQYLDEWMLRWRKFQTESDWQIEKNRQWWRKANIVTAGAVMGGLVMYTAGNATIRRQFGAPHFFDIGVDGK.LKEAICDTMTSRWRYTPQGYGRVMLVGLPTFFVFAISEHIQERRRLRAYVRQN.TVFGEQARRLVQNGK.IEEYLAVDIKASLPQNQTQLYAG.............................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVP.TVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANR..LGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDS...MQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.........................................................................................................................................................................................................NMFLFKDPVRRPQLSPEERAKVKINYAEWPEEFRDYDPDDPYKNSPEIIE......GLSSWNLFLWGV.ECAFIYQFYEVVFPKS....................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................................................................................................................................................................................................................................................................................................................NPVDHFRPNL.KFLSVYVE.....HQYVVDKWLHVKENWLKPWYLPWW.TPMYQAMTWYSQRNRNLMLVENHLNYRPYRYRRNDEDRENPY....................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
........................................................................................................................................................................................................................................................................................VFFSTYRSKRIVAPGFLKGPVMASRAFFDYYFQRAWCGCVQWVIPGEVRLWACGVPVIYFIHRYHNDHSLEPDFVEKAMIQRWGGSL.EEVRKLSPQDQLRIRAFTDLEKLYSAYGPKDTIVQPPGDLLPGKDYYH......................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDD...........NAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRK...QPELRADAGE......ASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
GTWSVLKKNCLNFVPGLALFASQSRDAFATWMKIYNRGYKYGPQEFSDQAEAYTPDYWKRGHSQEKNMWVDMKLSEEVSQKELAQLMHYKQDLWRMGHGLGLSLFLGGYALIPAFFCLSSDTFAPSCFCKTEEEKKAWREAQDMYRYRSAPSYIMDTKWHFD..FHAYPWNATQERAWDDLFEKNNVRRDPKVL.RPAAEMYDGFLKFYQIRRKSLRHLARSMNLP..TFPLLSRTCASTRVKDYWNLAWNEDYMVIT...QKLHHQMSDEDLHDYAWRRFLAPY....DKNLSRDEIMTRVNDYHEFLGPKFVEEGKAP..NMIILTNYVLGYYNDPAYLVE..........DISALDGNDFEYMAHYGKDAFLRRLEFENG..PLRDQVEAHTQKLIADRAAAAAAEA....................................................................................................................................................................................  
s2:
...........................................................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQ.YGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
HLEPMSVWYLSSWTCVWWYSFFFWLPVLWADMIVPSFVYNKLPVIHFIQEKRAEQKLRRVLDETYTQ.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................  
s2:
........................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................................HPPKLEDIPPSSATKGFFGAYMARLIDIKWMMNRSVELGREYYISAPTLYLFLWMFCWKGFVIMRYGDGKPP.......................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.................................................................................................................................................................................................................................................................................................................................................................................................................................................VGNGPTFHTAGDNN.NTSEIQNAFPINERGIRSSSPFPEPNTAIYDSYMPWTYFQPIDVKVDKMPAPEAKYYQHHTKKPWDVSTTDLIEIQSRKKYVQGVGYFLMMIYLYFLMPKEKSYSGTTGSDGFYVMLPKNQPEKFV  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRP.VHMEMLTNELESIPP...........................................................................  
s1:
................................................................................................................................................................................................................................................................................................................................................................................................................MFVFFVCDLVIMRILLCFCYSVWSRIIFVLFYNVFYICTELMFCIFDVYLFVGLCMFICLWFVLFNFYGLIVY..YCITYLNVYILFCIVFMYYMAFLFCFCFLLDFILFGSLLVGDAFMDVFFLRYLLCVLECFSLLCRCISTFLRMFCNLLSSHFLMLMFCDFVYFFIIFFLFFIMCDFIYFIIFTFAMLFCIIFYLFLYALDMFCALLQIFIFCNMIMQLIMDFLLLLSFHG  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSH...ALVHD........KSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDD.ANGTVRLAYRPVHMEMLTNELESIPP.............................................................................................................................  
s1:
................................................................................................................................................................................................FTVPVALCTKQVAAMDEPLKRHIDAYEARGEDVTIAVWREYVDGQRALLPYRWAKFRNEVTYLTSG....QIALTDLAFADLLLFVRFLTKCLFIFIVAVMAGRRSVFPSLE......PTSPFVEEIVKNWQPNRLRRVAGAEYMARDQAAAAAAAAA........................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTI...LCT...GGYGRVYFTTTSAKSCTGDGTAMVA........RAGLPAEDMEF...VQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTL.WTGEVISPRDGDDNAIVPG..LLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
..................................PKTLNQFRNFSYIVVAWLGFNKGFREKAANDAEWIAHQQRVRQQNVERHQAASAMMEA......................................................................................................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...........................................................................................VAPKTLNQFRNFSYIVVAWLGFNKGFREKAANDAEWIAHQQRVRQQNV..........................................................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMG...LPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...................................................................................................................................................................................................................................................................................................................................................................................................................................................................AFHDVSTDAIRQMQASEALQKHLENAQLAHRVCVAKALKAD...EPPVEKCALTWGEVVMRYNQWSEYRPAFHDSDAQKRYSKYWTKKRQA  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP............................................  
s1:
..........................................................................................................................................................................................SRVSNKISGGMACQTVVNHGYYLKPMTGNPYLCTQHDGVTTAYQQGFAPKDFNWLYRFRYNLLPQGMSGGFFSRNPYGRYVHWLEVSTIEKMRLQMFTMESVPCSVVSLILLVFTMWHSYRLAFLHPDITLYNLGLWSTKPWVQQQRFNKKKELDQDVYRWMTRVPEV..........MMDDPIREMYKMGIT.ANDPVYAMAKEQGVEHELTMTHAEYTSTSPDIRRVIANARK...............................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYT..ILCTGGYGRVYF...TTTSAKSCT.GDGTAMVARAGLPAEDMEFV.QFH....PTGI.........YGPGVLITERDVVS....RAITMEILKLPGISESAHIFA.....GVDVIVPTVH.YSMGGVPTL.WTGEV.ISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGE..ASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.................................................................................................................................................................................................................................KLYASDFERAQF.PANIV.PSDSVTFAKFLYKAV...........EPKGSFDAILKDFQTIAAAIPKLPIFWERTVVVSEVNEFKSL..........SAPTIFTLEWMQSNGMLDLLPDVAEVYETYVSAKMK..RVTAKIYVAPGK....EQDRALVDKARKVAEQVVKDNKQLAGYTLVPKVLVDRSIVEGFAVDVVNEAVG.....................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
......................................................................................................................................................................................SGRLRLYKEKLEGYNRFYSIVKTIKMVTMAKFRQAQVRIKTRDYTLRYTEKAF.SKPGQLVGDSPQAKAIYIP..VMTNRGSCG.ALNSNVVKVIDSVASSRAY.....LMPLGKRGIESLSKLYPS...SFRMGIVNDMHEPMHFA..YATYVWENAQQLCPEADRVHIIFHR.CVSA.......GSQKQCYYNIPAYEKWKEDLVDASSTENQKSRYLFANTLLNEDEQMIRDFYDFHATLAILNAVCENELSEQAARLVAVEGQLSNISTLQQKTSSLYNKTRQSSITSSLIEIISAMTSLEGNAAKGVQRTN..................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSK.......YTILCT.GGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTG..IYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGE...ASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSH...ALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDD..ANGTVRLAYRPVHMEMLTNELESIPP  
s1:
................................................................................................YTELSHMKFPVYYGAVGVVLGYFVVMWVVFLRMGSKHTARSEFKNDYLRVWRRRLGTGYEWADAWGPEMGT..FFKDLPEE.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFI..YQRAFGGQSIKQARRTCAASD......RTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...........................................................................................................................DMHSSDRFKAAWDE...IPLHMLGASHKQMFEWYWRAMYQLGL..RDPYRLTKLRSMLNWAALFSFMYLTYISIFYSSFYHVYMMDWPEHFKRENAREYALSHGHDVWAGDGKFIRPYFH...INPPMLTMTSEDI....................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFK.SKYTILCTGGYGRVYFTTTSA..KSCTGDGTAMVARAGLPAEDMEFVQ..FHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...........................................................................................................................................................................................................................................................................................................................TYFYANCGETGISGATMQVLLKLTLACCVVQVFAIRYFVFQRLTTKKQFVEDSTDLWESDGTEMD......GEEAVANLRIQHERIMPFMNDIKDKLDAQ......................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGAN.RLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALY..AEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
TMNFGNMTLGGAMATFGGQSNPMCNYTSPLAKKFVYKEVGKVHYPLRRHVFRTKVRTAAEIRFNEIVKRYMKEKMT.FKRGCYAATI...TNTVELDH.MGSIIPKDEYEVKRLTSYMTSKKMS....SDYKKHMQELWTRVLFVCESTNL..VGVTENAMHQNSRPGTDEEFMSIIWYSSFVTTLMAFVVTLFIWWYRYGQAPQYAEF.................................................................................................................................................................................................................................................................................................................................................  
s2:
..........................................AYPVIDHTYDCVVVGAG....GSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASD.RTGHAMLHTLYGQSFQYG.VNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.................................................................................................................................................................................................................................ELP.EAFEFIE.HK.........VTDKDIHSAYENMETLRLTVTRQDEFLFKETPVKCVTI.VGVNGENGVYPGHAYEITQLTPAPLTVEMPDGTVKKFFTSGGFAHINNEGSCDI.....NCVECI.........PLAELDLDAAEKALAQQQSALSSAHD.......EKAKAVIEIRIGVLESVIQSLKHMKE.................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMAL...YAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
......................................................................................................................................................................................................................................................PLATLKPVLAESVATQNVIRRMIGVTTNRKVNASAINSVAEKTKGEGLAGTTAVVARAHLYLLSRNPTDAVAEIDAVLPKVQDEALRRFAIGIRLRSHNELLDMKEASLGVSG..................GATESEVSDLRSKLQ.KDYKELVTSSPGCWLVELAAAEYTLYTG..ASEEAYKSFSSIEKKIQEYIKAPIHVSELVATADNTNEFSLIGFQVRRARPGVKPEGVSASVAEGMANVMADPAAVKALQQAKKAFEEALELVVTLQEANVGHHFHDFFPTTPDHYDKWTSEAARSAQQLIQEALTPHSVGLKPEAIDRIRVSMTNKAFYDSEEKLHALLKSAPKDKSIIASIRETFGPGPSTPISSSDQAVADAVESVHLAVVSSDTAGATDYAKRGKEIAKALAKQLLYRTQVQKCVALTEMNCLQEAVDVVTPVIDANEYIYMWRAFLARSRAYKGLGLITNADKDLKELNRLKHSLTERTPYEKK  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITME..ILKLPGISESAHIFAGV..DVIVPTVHYSMGGVPTLWTGE...VISPRDGDDNAIVPGLL..AAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSH....ALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP.......................................................................................................................................................................................................................................  
s1:
.............................................................................................................................................................................................MFWLCLVCLSVSHKMIGLCYLLVAILSGFVGYVYSLFIRLELSLIGCGIL....FGDYQFYNVLITSHGLIMVFAFIMPVMMGGLVNYFIPVMAGFPDMVFPRLNNMSFWMYLAGFGCVVNGFLTEEGMGVGWTLYPTLICIDFHSSLACDFVMFAVHLLGISSILNSINLLGTL.....FCCRRKFFSFLSWSLFIWAALITAILLIITLPVLAGGVTLILCDRNFNTSF..Y..DVVGGGDLILFQHIFWFFGHPEVYIILLPVFGLISTIVEVIGFRCVFSTVAMIYSMILIAILGMFVWAHHM.FVVGMDVDSRAYFGGVSILIGLPTCVKLFNWIYSFLYTDMIITFEVYFVIMFIFMFLIGAVTGLFLSNVGIDIMLHDTYFVVGHFHYVLSLGAVVGFFTGFIHFLAKWLPIELYLFWMFYFISTLFIGSNMLFFPMHSLGMYAFPRRISDYPVSFLFWSSFMLYGMLLLASLILFLCALFCVFLFWDYCLFFVSLFVFSLYCFFYFSTWLPCVMVLYLLLVDFAHIVLDYLFLILCFCFVFFIFFWQSLFLFFYI  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTG....GYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYG.PGVLITERDVVS.RAITMEILKLPGISESAHIFAGV.DVIVPTVH.....YSMGGVPTLWTGEVISPRDGDDNAIVPGLLAA...GECACASV.HGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILN...NKGDIPIARIRERMKETMALYAEDSMQTG.KNIIEECYRDFSHALVHD.KSPVWN..SNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP.......................................................................................................................................................................................................................................  
s1:
................................................................................................................................................................................................................................................................................................................................................................................................................................ASCR...TGRLPMPDDPLFNSTHMHGLRHSSRIAGLGMIAVIWIMYEKLRHSHHYITYKGPENPFARIRHRRFPGGAFMFGWGNNGLNRDCGIKEFECWAGYTGKEYTYV  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMK.....HTLTYLDDANGTVRLAYR..PVHMEMLTNELESIPP.....................  
s1:
VAKISSIERASTYLRFSTLRVHPHHEPNFRARPVGWKAWNSKQYMDPWAPYPL...TSPVRHVDRPFSGMWFGMGHFALKNFFGPLNWKFWARVSFFGTLGWAYSLSSYALRMHRNGWEWKNRGAVF.......................................................................................................................................................................................................................................................................................................................................................................................................................................  
s2:
.................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQG...GINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
..................................................................................................KVLIADLPMMWPSDMRRFEKEGGVWGQQFRQRRRQLTFALTISAASTLLGSWYVVMRRRN.TYFVLFSTFSGFSVLGFCIGMSLAPLWYENVANNK......ETSMMRRVWWAKECAKHWD...........................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFG..GQSIKQARR..TCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
TPYQDKSYPVQPHNLDELQQPPDSWRKSPIMSKLMDQSLPVYDDVVTGVGRLYWQEPARVWHLFEADDTLMLEEHDREEWNDRPYVAVNHLYEPPIGSEERPIRVEGTGNPGDQQIVLCFGNCAPHVPQSNYYMMMKGYNKTKCPMCQQWFYIHNRPWLVMHPDWT.DEPAAD...EGPAYTFSEIEA...EFDRDFHEFGVYLNAE..........................................................................................................................................................................................................................................................................................................................................................................................  
s2:
...................................................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKL...YPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGF.IYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.........................................................................................................................................................................................................................................................AEARAVLQAQSHRTVSAVVPGKMFMRHWIVAEQSTVSVVNRVISGMVAVFTMIWAAGYATLGYNGHNSAHVAGWIFIAYWVVLHTH.IMWLAPTML................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILK..LPGISESAHIFAGVDVIVPTVHYSMGGVPTLWT.....GEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
..........................................................................................................................................................................................................................................................................PG..QLANYSSPLYMYSHLIKNSTAKTPQLYTA.....KDNSKTAM.HLLTRRGATANYTVNRWYLKEKVDSSNRMRLEGLYECVLCASCTGSCPQYWWNREHFLGPAVLLQSYRWLVEPLDR...............DFDERVRMF.....ETG.TLVNMCHNIFNCSIT...CPKFLNPGLASKEIKRLSSPAAKRVGPAIE.....................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVH.........GANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...............................................................................................................................................................................................................................................................................................................................................EDHRKYKVQREELPRMPHFNDFNDPRFCGTTNKQKNGILAYYQWLHCIGNWGE......EHSMCKKMRWYVERMMHETWLEKWEEKRALGHFDHTILYGVKP.WK.......EFEPLYQPVKKNRKGAYEYWLDRDFEPLYDADAADWREKAPILHDMFVLGKKPVA.  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPEL.RADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQ...TGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVR.MKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.............................................................................................................................................................................................................................................................................................................................................................WPSKLPLTKNWYYHLS.RRD....SIADETRQYMVVGDFLLLFVVSFSMYRLYVLNRNNTYQTHLSHLI.....NYPPAIIANEFDFKDSNANRLVERKDLDAYREDVVRCRAS.....................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGD.IPIARIRERMKETMALYAEDSMQTG.KNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
....................................................................................................................................................................................................................................................................................YGHALELDTHNYKFNGEPPSWMKTHAKTEEETSFAKSVLPHIDFASSYECL.LFDADRLNTN......LNRKEFGNEIKYRLEKQANTVARAQQLLKDKKAGTGPDAAKIENTLIARIFDEEHVQAEMKYVKCIRANELAEDNRLDI...LPGGSPNSLREKTR.WNLN....TELHPADRAEIGARLTAWLPEKYHIVYFDDFQTVA..ANDATARREMLEIVESVQKEYTAEAKEGGYESDLKETVAELMDDVDPTRAITMEAIKSCKDLQQLEDWSRQVHEYNGDDRIIEIYARAAEITKNAEHQALVKQMREWRKLATK  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLW..TGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGR...KQPELRADAGEASIADLDRILNN..KGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP..............................................................................................  
s1:
.............................................................................................................................................................................................................................................................................................................................................................................................................SLSTILYSPIGTSMMIMLAYNVIVICSKHVNYSLEITAKDYVQDQQLLTIMRYGILSCILLGMEVMFIEIG..................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAE..DSM..QTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
............................................................................................................................................................................................................................................PRPFGVWAPATTLAEYRA..........RIP..NPFAYSFKWVYSMKREVFY.....PPEALAHFKDPQQFKDAVDTVIAMRVSD....KIFGEGQKLPRHPVILMLMVLATHGFIIFSGLKYYYGTYMPANNPTWRKTVNKEWEEAINNSPWDHMSHVWQYSDEYAAALGDTAAPGQRKFYIPA...............................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKE..GRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
........................PATVKRPLWSLLLPQTYTSRIHTLAFHAPSILFMIAVCAIISKQSYYRSSLADEDPKTYDRIDRRAYVALPDGRMALVYPIIDTQTSFTRTVISFLDAVNPF..........................................................................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQG.GINAALANC....EEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQ.RAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.............................................................................................................................................................................................................................................................................................IYTTWGSVPCEDWARNESWLKRITSQSDYRSFEFWHVPQADVPAGLRLNAVERYLLSSLENDTDRLLHVSWCEDFDPYWHDRVGSLEMLYKI....VYTNDYPLYRYIFGNC.MHKVAEKEYMLRKLNYLKSVLFWAGRTERCYTSIVKARYYVQRCVWNALERERYLCACVEAVDSFGKKVPEELRQKVMPELEVALVSMRHWV..WDCPNGKRTFTRRLA..................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPT.......LWTGEVISPRDGDDNAI..VPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWN..............SNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANG....TVRLAYRPVHMEMLTNELESIPP  
s1:
.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SLADKIVRGPPKSVYYTHPRYVMSRDKMLHTIWVDIGIFQTCAYALFPFFSAAYFFK  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP..............................................  
s1:
................................................................................................................................................................................................................................................................................TYMLAFNSKAKARPNFGLRGV.GYWTSEVYHK.........PGQNYWMVVCCAGPFLLVGAIMMDGFWSKLDDIAGGGPSA..LDYGWRSQDRKPWDFSFDIGEGYAAGPAVYRPASGAVDL............................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACAS...VHGANRL.GANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
................................................................................................................................................................KAVLQLVRFDPETNSSRVESYEYDKHHEYMVLDLLIAVKAHQDPTLAFRSSCCEGVCGS.CAMNINGINSLACITFAQHVTTVAPLPNFPVIKDFVVDLRHFFQQYAYIRPYVRNANLHRSQVDGIVERYNTVARVLSGVSPSEGRAMEKAQEELRETTVAALLRIADAAVDAGNATQALSVLEKVEQQ..GVVLDSTRVTEMIERALKNFAAKS..................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGY..GRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVS.RAITMEILKLPGISESAHIFAG.VDVIVP...TVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
................................................................................................................................................................YETFTPKTLSG..RLVMPGNINLLTVSPLYCAVLCIAAATWGVFYWDIYCRKNYE...TVLIARP....KDM..........................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
MFVRVIFVGVSGVFVFLSLPAICIVYLTFCLCGLFCIMFGSFIFIDYCFICFFACLLFCLVCLLCDLFVDSLRGLFDVCCFIRCIQYCFVWFIISELLLFLSLFYVVFSLVLFVSVEFAFVFVIPVMFSCLICDFGFVFYWYFIDIFNLLINTFLLFVSGLFVNFVLFLFWFRFFLCVLFMLWVGILFGFLFLWNQVWEFALLFVTCSCGVFGSILFLIDLLHFSHVFLGIFLLFLCFSRCFNFLCMDTRFVFLYVVCLYWHFVDCVWFFLLRFVYFDVLSVV......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................  
s2:
...............................................................................................................................................................................................................................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...............................................MFLGGFVPRRFTQLNRD..PWWMFFIFSVGAWIGEYPAMQIKYNARDLV...LDPHRYVWSHLDDHH................................................................................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
............................................................................................................................MGHEETTFSRGNRTRNNALQHIYGLMGLCGVGCVLALFSFVSGQRRIQTTITADGTMTKGTCPT...............................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGV.......NFYN.EYYCLDLITEDG.CCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
......................................................................................................................................................MAFILSFWMIFLLDSVIVLLSFVCFVCVWICALLFSTVLLVSKLNNIYCTWDFTASKFIDVYWFTIGGMFSLGLLLRLCLLLYFGHLNFVSFDLCKVVGFQWYWVYFIFGETTIFSNLILESDYMIGDLRLLQCNHVLTLLSLVIYKLWLSAVDVIHSFAISSLGVKVDCIPGRCNEIVLFSSNNATVYGQCSELCGVLHGFMPIVICFI................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLIT..EDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTT...SAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGI.....YGPGVLITERDVVSRAITME..ILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWT....GEVISPRDGDDNAIV....PGLLAAGECA..CASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
......................................................................................................................................................................YTRWKCDR......IPVLQLKLFTQEYNIMALVGLLSMVFLFKHASYCSEETERKNGWWAGYP........YWRDPIARRNEIRYKQLINSNDVDITDPKWTGCSKEQ.................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVA.RAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
................................................................................................................................................................................................................................................................................TYMLAFNSKAKARPNFGLRGV.GYWTSEVYH.KPGQNYWMV..VCCAGPFL...LVGAIMMDGFWSKLDDIAGGGPSA..LDYGWRSQDRKPWDFSFDIGEGYAAGPAVYRPASGAVDL............................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRL.GANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
..............................................................................................................................................................................................................................................................................................................................TMNFGNMTLGGAMATFGGQSNPMCNYTSPLAKKFVYK..EVGKVHYPLRRHVFRTKVRTAAEIRFN......EIVKRYMKEKMTFKRGCYAATITNTVE.........LDHMGS.IIPKDEYEVKRLTSYMTSKKMS.SDYKKHMQELWTRVLFVCESTNLVGVTENAMHQNSRPGTDEEFMSIIWYSSFVTTLMAFVVTLFIWWYRYGQAPQYAEF  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLT...YLDDANGTVRLAYRPVHMEMLTNELESIPP..................................  
s1:
....................................................................................................................................................................................................................................................................................YGHALELDTHNYKFNGEPPSWMKTHAKTEEETSFAKSVLPHIDFASSYECLLF.DADRLNTN......LNRKEFGNEIKYRLEKQANTVARAQQLLKDKKAGTGPDAAKIENTLIARIFDEEHVQAEMKYVKCIRANELAEDNRLDILPGGSPNSLREKTRWNLNTELHPADRAEIGARLTAWLPEKYHIVYFDDFQTVAANDATARREMLEIVESVQKEYTAEAKEGGYESDLKETVAELMDDVDPTRAITMEAIKSCKDLQQLEDWSRQVHEYNGDDRIIEIYARAAEITKNAEHQALVKQMREWRKLATK  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLW..TGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGR...KQPELRADAGEASIADLDRILNN..KGDIPIARIRERMKETMAL....YAEDS....MQTG.KNIIEECYRDFSHALVH..DKSPV......WNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRL.AYRPVHMEMLTNELESIPP..................................................................  
s1:
......................................................................................................................................................................................................................................................................................................................................................FFGKGWDNAALDTIFSSMLRKPEVNDRIRTQYASTMD...PRDADVLRRLGEVSKENKTFIRVFLPPHL.GDPHRLLKCYSLMAYPILDDKGGQLKVEM.DGCKL.DAFADPDDDYSKVVIPHIELVEYLAKSLLETMKWEATPRGAASLLESLYRGAEIPDHVFQTPAVIERLEDYKDGNKVIS  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDI..PIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDAN.GTVRLAYRPVHMEMLTNEL...ESIPP.......................  
s1:
.....................................................................................LHFPLSPPPIEIDYLDSDPLEFAVRTEARRWGFDDLQYMRELAFVRIKENPSIGDFRRMTPEERRDLFWGSD....RQDFFRYITLKLTGHPEHLYHRGW..................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPF.LRTK......DGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLI..TEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
TPYQDKSYPVQPHNLDELQQPPDSWRKSPIMSKLMDQSLPVYDDVVTGVGRLYWQEPARVWHLFEADDTLMLEEHDREEWNDRPYVAVNHLYE.PPIGSEERPIRVE.GTGNPGDQQIVLCFGNCAPHVPQSNYYMMMKGYNKTKCPMCQQWFYIHNRPWLVMHPDWT.DEPA....ADEGPAYT..FSEIEAEFDRDFHEFGVYLNAE..........................................................................................................................................................................................................................................................................................................................................................................................  
s2:
...................................................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYD..VACISKL...YPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGF.IYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
.............................................................................................................................................................................................MFWLCLVCLSVSHKMIGLCYLLVAILSGFVGYVYSLFIRLELSLIGCGIL....FGDYQFYNVLITSHGLIMVFAFIMPVMMGGLVNYFIPVMAGFPDMVFPRLNNMSFWMYLAGFGCVVNGFLTEEGMGVGWTLYPTLICIDFHSSLACDFVMFAVHLLGISSILNSINLLGTLFCC.....RRKFFSFLSWSLFIWAALITAILLIITLPVLAGGVTLILCDRNFNTSF..Y..DVVGGGDLILFQHIFWFFGHPEVYIILLPVFGLISTIVEVIGFRCVFSTVAMIYSMILIAILGMFVWAHHM.FVVGMDVDSRAYFGGVSILIGLPTCVKLFNWIYSFLYTDMIITFEVYFVIMFIFMFLIGAVTGLFLSNVGIDIMLHDTYFVVGHFHYVLSLGAVVGFFTGFIHFLAKWLPIELYLFWMFYFISTLFIGSNMLFFPMHSLGMYAFPRRISDYPVSFLFWSSFMLYGMLLLASLILFLCALFCVFLFWDYCLFFVSLFVFSLYCFFYFSTWLPCVMVLYLLLVDFAHIVLDYLFLILCFCFVFFIFFWQSLFLFFYI  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTG....GYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYG.PGVLITERDVVS.RAITMEILKLPGISESAHIFAGV.DVIVPTVH.....YSMGGVPTLWTGEVISPRDGDDNAIVPGLLAA...GECACASV.HGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNN...KGDIPIARIRERMKETMALYAEDSMQTG.KNIIEECYRDFSHALVHD.KSPVWN..SNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP.......................................................................................................................................................................................................................................  
s1:
MFVRVIFVGVSGVFVFLSLPAICIVYLTFCLCGLFCIMFGSFIFIDYCFICFFACLLFCLVCLLCDLFVDSLRGLFDVCCFIRCIQYCFVWFIISELLLFLSLFYVVFSLVLFVSVEFAFVFVIPVMFSCLICDFGFVFYWYFIDIFNLLINTFLLFVSGLFVNFVLFLFWFRFFLCVLFMLWVGILFGFLFLWNQVWEFALLFVTCSCGVFGSILFLIDLLHFSHVFLGIFLLFLCFSRCFNFLCMDTRFVFLYVVCLYWHFVDCVWFFLLRFVYFDVLSVV......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................  
s2:
...............................................................................................................................................................................................................................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
VAKISSIERASTYLRFSTLRVHPHHEPNFRARPVGWKAWNSKQYMDPWAPYPL...TSPVRHVDRPFSGMWFGMGHFALKNFFGPLNWKFWARVSFFGTLGWAYSLSSYALRMHRNGWEWKNRGAVF.......................................................................................................................................................................................................................................................................................................................................................................................................................................  
s2:
.................................................AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQG...GINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...........................................................................................................................DMHSSDRFKAAWDE...IPLHMLGASHKQMFEWYWRAMYQLGL..RDPYRLTKLRSMLNWAALFSFMYLTYISIFYSSFYHVYMMDWPEHFKRENAREYALSHGHDVWAGDGKFIRPYFH...INPPMLTMTSEDI....................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFK.SKYTILCTGGYGRVYFTTTSA..KSCTGDGTAMVARAGLPAEDMEFVQ..FHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
......................................................................................................................................................MAFILSFWMIFLLDSVIVLLSFVCFVCVWICALLFSTVLLVSKLNNIYCTWDFTASKFIDVYWFTIGGMFSLGLLLRLCLLLYFGHLNFVSFDLCKVVGFQWYWVYFIFGETTIFSNLILESDYMIGDLRLLQCNHVLTLLSLVIYKLWLSAVDVIHSFAISSLGVKVDCIPGRCNEIVLFSSNNATVYGQCSELCGVLHGFMPIVICFI................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLIT..EDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTT...SAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGI.....YGPGVLITERDVVSRAITME..ILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWT....GEVISPRDGDDNAIV....PGLLAAGECA..CASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
..........................................................................................................................................................................................SRVSNKISGGMACQTVVNHGYYLKPMTGNPYLCTQHDGVTTAYQQGFAPKDFNWLYRFRYNLLPQGMSGGFFSRNPYGRYVHWLEVSTIEKMRLQMFTMESVPCSVVSLILLVFTMWHSYRLAFLHPDITLYNLGLWSTKPWVQQQRFNKKKELDQDVYRWMTRVPEV..........MMDDPIREMYKMGIT.ANDPVYAMAKEQGVEHELTMTHAEYTSTSPDIRRVIANARK...............................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYT..ILCTGGYGRVYF...TTTSAKSCT.GDGTAMVARAGLPAEDMEFV.QFH....PTGI.........YGPGVLITERDVVS....RAITMEILKLPGISESAHIFA.....GVDVIVPTVH.YSMGGVPTL.WTGEV.ISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGE..ASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
...........................................................................................................................................................................................................................................................................................................................TYFYANCGETGISGATMQVLLKLTLACCVVQVFAIRYFVFQRLTTKKQFVEDSTDLWESDGTEMD......GEEAVANLRIQHERIMPFMNDIKDKLDAQ......................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGAN.RLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALY..AEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
................................................................................................YTELSHMKFPVYYGAVGVVLGYFVVMWVVFLRMGSKHTARSEFKNDYLRVWRRRLGTGYEWADAWGPEMGT..FFKDLPEE.........................................................................................................................................................................................................................................................................................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFI..YQRAFGGQSIKQARRTCAASD......RTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
EDHRKYKVQREELPRMPHFNDFNDPRFCGTTNKQKNGILAYYQWLHCIGNW..GEEHSMCKKMRWYVERMMHETWLEKWEEKRALGHFDHT.....ILYGVK..PW..KEFEPLYQPVKKNRKG.AYEYWLD.RDFEPLYDADAADWREKAPILHDMFVLGKKPVA.......................................................................................................................................................................................................................................................................................................................................................  
s2:
...........AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
................................................................................................................................................................................................................................................................................................................................................................................................................................ASCR...TGRLPMPDDPLFNSTHMHGLRHSSRIAGLGMIAVIWIMYEKLRHSHHYITYKGPENPFARIRHRRFPGGAFMFGWGNNGLNRDCGIKEFECWAGYTGKEYTYV  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMK.....HTLTYLDDANGTVRLAYR..PVHMEMLTNELESIPP.....................  
s1:
............................................................................................................................................................................................................................................PRPFGVWAPATTLAEYRAR..........IP..NPFAYSFKWVYSMKREVFY.....PPEALAHFKDPQQFKDAVDTVIAMRVSD....KIFGEGQKLPRHPVILMLMVLATHGFIIFSGLKYYYGTYMPANNPTWRKTVNKEWEEAINNSPWDHMSHVWQYSDEYAAALGDTAAPGQRKFYIPA...............................................................................  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKE..GRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP  
s1:
........................................................................................................................................................................................................................................................MLRRHAYKTAACVTAIQ...VARAVHSIAVLQNSTPATTAQKLGSVVSKEEVAAVNKVPASLLEKVCNPRLVAFTAMDLARTRFAPLIAT..ITD.EVDYTSIEQQVAKRFSKDPSKLQPTPGALKHFRENNWKDMKSLITFYEETMYPIRMKHKEYKYHELTSFHIKDVLKRGLSAFKQSYLDEQREEQTKVKAYMKSCDDFVRTAVKDAFDTSVCNDIANILRIGGETHAHAHRMALKILDDMNL.MRVPYSAATTEILQAVAFNDGPFDNSPLLFEMIEYPERGEVHVGTASLENISDEVLKLISNRHQTPLDDGVLIRSPDTHPNLQRSPE  
s2:
AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITERDVVSRAITMEILKLPGISESAHIFAGVDVIVP.TVHYSMGGVPTLWTGEVIS..PRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRK.QPELRA..DAGEASIADLDRILNNKGD....IPIARIRERMKETMALYAEDSMQTGKNIIEECYRDFSH.ALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRM.........KHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP.................................................................  
s1:
MLRRTFTRLALSRAYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSIHYGGKQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITEGARGEGGYLVNSEGERFMERYAPKAKDLASRDVVSRAITMEILAGRGCGPKKDHVMLQLHHLDPATLHKKLPGISESAHIFAGVDVTKEPIPIVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYAAVFRTEDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVRKESRGAHARDDYQERDDHNWMKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPPAKRVY  
s2:
.............AYPVIDHTYDCVVVGAGGSGLRAAMGVAASGYDVACISKLYPSRSHTIAAQGGINAALANCEEDDWRWHVYDTVKGSDWLGDQDAIQYMCQEAPCVVSELESMGLPFLRTKDGFIYQRAFGGQSI....KQARRTCAASDRTGHAMLHTLYGQSFQYGVNFYNEYYCLDLITEDGCCRGVMAMSIDDGTIHRFKSKYTILCTGGYGRVYFTTTSAKSCTGDGTAMVARAGLPAEDMEFVQFHPTGIYGPGVLITE..............................RDVVSRAITMEIL..........................KLPGISESAHIFAGVDV......IVPTVHYSMGGVPTLWTGEVISPRDGDDNAIVPGLLAAGECACASVHGANRLGANSLLDIVVFGKSCANTVIFNLTKEGRKQPELRADAGEASIADLDRILNNKGDIPIARIRERMKETMALYA.....EDSMQTGKNIIEECYRDFSHALVHDKSPVWNSNLIEALELRNLLTNAMMTISGAVVR....................MKHTLTYLDDANGTVRLAYRPVHMEMLTNELESIPP.....  

"Adjust for PAE" is checked in the distance restraint options, but the
reference model has no PAE matrix assigned. This option has been ignored.  

> isolde restrain distances "#1.2/K5" templateAtoms "#9/K5" perChain false
> adjustForConfidence false useCoordinateAlignment true kappa 4.40 fallOff
> 2.50 groupName "Reference Distance Restraints"

ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
[Repeated 1 time(s)]Computing secondary structure  
RMSD between 470 pruned atom pairs is 1.746 angstroms; (across all 498 pairs:
2.464)  
RMSD between 5 pruned atom pairs is 2.947 angstroms; (across all 28 pairs:
28.607)  
RMSD between 4 pruned atom pairs is 3.343 angstroms; (across all 23 pairs:
33.086)  
RMSD between 3 pruned atom pairs is 3.217 angstroms; (across all 19 pairs:
34.885)  
RMSD between 3 pruned atom pairs is 2.636 angstroms; (across all 16 pairs:
32.665)  

> isolde restrain torsions #1.2/K5 templateResidues #9/K5 adjustForConfidence
> false sidechains true springConstant 250.00 alpha 0.20

ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
[Repeated 1 time(s)]Computing secondary structure  

> isolde sim start #1.2/K5

Loading residue template for FAD from internal database  
Sim termination reason: None  
ISOLDE: stopped sim  
Loading residue template for 3PE from internal database  
Loading residue template for ATP from internal database  
Loading residue template for LPP from internal database  
Loading residue template for PC1 from internal database  

Chain HM, residue 1 specifies more than one residue! The simulation can still
run, but this will probably cause problems later if not rectified by
renumbering.  

> show #!9 models

> hide #!1 models

> select #19

Nothing selected  

> select #9

7523 atoms, 7592 bonds, 6 pseudobonds, 498 residues, 2 models selected  

> select #9&ligand

Nothing selected  

> hide #!9 models

> show #!1 models

Deleted the following atoms from residue FAD FD1: HN  

> select #1/K5

9024 atoms, 9120 bonds, 594 residues, 1 model selected  

> select #1/K5

9024 atoms, 9120 bonds, 594 residues, 1 model selected  

> isolde ignore ~#1/K5

ISOLDE: currently ignoring 498 residues in model 9  
ISOLDE: currently ignoring 157 residues in model 6  
ISOLDE: currently ignoring 246 residues in model 7  
ISOLDE: currently ignoring 16261 residues in model 1.2  
ISOLDE: currently ignoring 3296 residues in model 3  
ISOLDE: currently ignoring 594 residues in model 8  

> isolde ~ignore

> isolde ignore ~#1/K5&#1

ISOLDE: currently ignoring 16261 residues in model 1.2  

> select #1/K5

9024 atoms, 9120 bonds, 594 residues, 1 model selected  

> select ~#1/K5&#1

267207 atoms, 270543 bonds, 35 pseudobonds, 16261 residues, 23 models selected  

> hide sel atoms

> hide sel cartoons

> select #1/K5

9024 atoms, 9120 bonds, 594 residues, 1 model selected  

> isolde sim start #1.2/K5

ISOLDE: started sim  

> show #!9 models

> hide sel atoms

> show sel cartoons

> ui mousemode right "isolde tug residue"

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 10 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> save /Users/rafaelrocha/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV8.cxs

> isolde sim start #1.2/K5

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: stopped sim  

> isolde ~ignore

[Repeated 1 time(s)]

> select #1

276231 atoms, 279663 bonds, 35 pseudobonds, 16855 residues, 23 models selected  

> show sel cartoons

> select #1/K5

9024 atoms, 9120 bonds, 594 residues, 1 model selected  

> isolde sim start #1.2/K5

ISOLDE: started sim  

> select #1

276231 atoms, 279663 bonds, 35 pseudobonds, 16855 residues, 23 models selected  

> show sel atoms

> select #1/K5

9024 atoms, 9120 bonds, 594 residues, 1 model selected  

> close #1.2.9

> close #1.2.7

> ui tool show "Ramachandran Plot"

> isolde pepflip #1.2/K5:553

> isolde pepflip #1.2/K5:377

Unable to flip peptide bond after 50 rounds. Giving up.  

> isolde pepflip #1.2/K5:446

> isolde pepflip #1.2/K5:93

> isolde pepflip #1.2/NF:86

> isolde pepflip #1.2/K5:240

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/K5:240

> isolde pepflip #1.2/K5:241

> isolde pepflip #1.2/K5:240

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 5 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> isolde sim start #1.2/K5:240

ISOLDE: started sim  

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 2 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> select #1/K5

9024 atoms, 9120 bonds, 594 residues, 1 model selected  

> isolde sim start #1.2/K5

ISOLDE: started sim  

> select clear

[Repeated 1 time(s)]

> isolde pepflip #1.2/K5:579

[Repeated 2 time(s)]

> isolde pepflip #1.2/K5:580

> select #1

276231 atoms, 279663 bonds, 35 pseudobonds, 16855 residues, 23 models selected  

> show sel atoms

> isolde pepflip #1.2/K5:552

> isolde pepflip #1.2/K5:550

[Repeated 1 time(s)]

> select clear

> isolde pepflip #1.2/K5:551

> isolde pepflip #1.2/K5:552

> isolde pepflip #1.2/K5:235

> isolde pepflip #1.2/K5:451

> isolde pepflip #1.2/K5:23

> isolde pepflip #1.2/K5:285

[Repeated 1 time(s)]

> isolde pepflip #1.2/K5:23

[Repeated 1 time(s)]

> isolde pepflip #1.2/K5:24

> isolde pepflip #1.2/K5:22

> isolde pepflip #1.2/K5:21

> isolde pepflip #1.2/K5:20

> isolde pepflip #1.2/K5:462

> isolde pepflip #1.2/K5:239

[Repeated 1 time(s)]

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/K5:265

[Repeated 1 time(s)]

> isolde pepflip #1.2/K5:264

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/K5:462

> isolde pepflip #1.2/Mg:238

> isolde cisflip #1.2/K5:256

> isolde pepflip #1.2/K5:249

[Repeated 2 time(s)]

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/K5:233

Tugging of non-polar hydrogens is not enabled. Applying tug to the nearest
bonded heavy atom.  

> isolde pepflip #1.2/K5:31

> isolde pepflip #1.2/K5:32

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 24 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> save /Users/rafaelrocha/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV8.cxs

Taking snapshot of stepper: combination  

> select #1/K5

9024 atoms, 9120 bonds, 594 residues, 1 model selected  

> isolde sim start #1.2/K5

ISOLDE: started sim  

> isolde pepflip #1.2/K5:32

> select #1/K5

9024 atoms, 9120 bonds, 594 residues, 1 model selected  

> ui tool show "Ramachandran Plot"

> isolde pepflip #1.2/K5:405

> isolde pepflip #1.2/K5:404

> isolde pepflip #1.2/K5:230

> isolde pepflip #1.2/K5:563

> isolde pepflip #1.2/K5:92

> isolde pepflip #1.2/K5:370

> show sel atoms

> isolde pepflip #1.2/K5:47

[Repeated 1 time(s)]

> isolde pepflip #1.2/K5:48

> isolde sim stop

Sim termination reason: None  
ISOLDE: Checking and correcting nomenclature for (pseudo)symmetric side
chains...  
ISOLDE: Corrected atom nomenclature of 14 residues in model #1.2 to IUPAC-IUB
standards.  
ISOLDE: stopped sim  

> hide #!9 models

> select clear

> save /Users/rafaelrocha/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp_NOSEQ/superComplexConsolidation/superComplexConsolidatedV8.cxs

Taking snapshot of stepper: combination  

——— End of log from Thu Mar 6 15:08:05 2025 ———

opened ChimeraX session  

> show #!2 models

> hide #!2 models

> show #3 models

> hide #3 models

> show #!4 models

> hide #!4 models

> show #!6 models

> hide #!6 models

> show #!7 models

> show #8 models

> show #!9 models

> hide #!9 models

> show #!9 models

> show #!2 models

> show #3 models

> volume #2 level 0.192

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J436_002_volume_map_sharp_WITHSEQ/"

'/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J436_002_volume_map_sharp_WITHSEQ/' has no suffix  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J436_002_volume_map_sharp.mrc"

Opened cryosparc_P43_J436_002_volume_map_sharp.mrc as #10, grid size
500,500,500, pixel 1.21, shown at level 0.109, step 2, values float32  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp.mrc"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #11, grid size
500,500,500, pixel 1.21, shown at level 0.118, step 2, values float32  

> hide #!7 models

> hide #8 models

> hide #!9 models

> hide #3 models

> hide #!2 models

> hide #!10 models

> show #!10 models

> hide #!10 models

> volume #10 level 0.1306

> volume #10 step 1

> volume #11 step 1

> volume #11 level 0.145

> volume #11 level 0.1676

> ui tool show "Hide Dust"

> surface dust #11 size 7.25

> volume #11 level 0.1766

> volume #11 level 0.1585

> color
> #1/Av,lx,Mr,LY,LO,Np,AG,KI,Ar,Jw,JN,J6,Y,JJ,Il,Iy,I0,Ks,AV,t9,t0,tg,t2,t7,t3,t5,t4,t8,tf,t1,ta,t6,td,tc,tb,te,Ix
> mediumvioletred

> color
> #1/A0,Ab,Aj,AU,E,BK,Aq,BI,BP,IE,IY,C0,C1,C2,C3,C4,C5,C6,C7,C8,C9,B,C,D,F9,FF,A,Es,Eq,Ek,Fy,Fz,FH,a,GT,FL,FO,E1,F9,E4,Ev,R,JC,D6,v0,v1,v2,v3,v4,v5,v6,v7,v8,v9,vA,vB,vC,vD,vE,vF,vG,vH,vI,vJ,vK,vL,vM,vN,vO,vP,vQ,vR,vS,vT,vU,vV,vW,vX,vY,vZ,va,vb,vc,vd,ve,vf,vg,vh
> limegreen

> color
> #1/Kp,K5,JI,NF,NM,L3,M,LR,Jx,Ke,Mq,LG,TB,Mg,r0,r1,r2,r3,r4,r5,r6,r7,r8,r9,rA,rB,rC,rD
> goldenrod

> hide #!11 models

> show #!11 models

> color zone #4 near #1

> color zone #11 near #1

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J436_002_volume_map_sharp_NOSEQ/lipidLayer/lipidLayer.mrc"

Opened lipidLayer.mrc as #12, grid size 500,500,500, pixel 1.21, shown at
level 9e-05, step 2, values float32  

> volume #12 level 0.0614 step 1

> surface dust #12 size 12.1

> color zone #11 near #1 distance 6

> color zone #11 near #1 distance 30

> hide #!1 models

> volume #12 level 0.06961

> volume #11 level 0.1766

> volume #11 level 0.1314

> save
> /Users/rafaelrocha/supercomplex/Manuscript/figures/figureA/supercomplexMapcolored.cxs

Taking snapshot of stepper: combination  

> set bgColor white

> camera ortho

> lighting soft

> lighting flat

[Repeated 1 time(s)]

> lighting soft

> lighting full

> lighting soft

> graphics silhouettes false

> graphics silhouettes true

> graphics silhouettes false

> graphics silhouettes true

> graphics silhouettes false

> graphics silhouettes true

> lighting shadows true intensity 0.5

> lighting shadows false

> lighting shadows true

> lighting shadows false

> lighting shadows true

> lighting shadows false

> lighting shadows true

> save
> /Users/rafaelrocha/supercomplex/Manuscript/figures/figureA/supercomplexMapcolored.cxs

Taking snapshot of stepper: combination  

> save /Users/rafaelrocha/Desktop/image1.png supersample 3

> lighting flat

> lighting soft

> save
> /Users/rafaelrocha/supercomplex/Manuscript/figures/figureA/supercomplexMapcoloredView1.cxs

Taking snapshot of stepper: combination  

——— End of log from Thu Mar 6 18:11:35 2025 ———

opened ChimeraX session  

> hide #!11 models

> show #!11 models

> hide #!12 models

> hide #11.1 models

> show #11.1 models

> show #!12 models

> hide #11.1 models

> hide #!11 models

> show #!11 models

> show #11.1 models

> ui tool show "Volume Viewer"

> volume #11 level 0.2041

> volume #11 level 0.2854

> volume #12 color #ffb2b2a5

> volume #12 color #ffb2b27f

> volume #12 color #ffb2b261

> volume #12 color #ffb2b253

> volume #12 color #fffb00

> volume #12 color #fffb004b

> volume #12 color #fffb001c

> volume #12 color #ff9300

> volume #12 color #ff930025

> close session

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J436_002_volume_map_sharp_NOSEQ/lipidLayer/lipidLayer.mrc"

Opened lipidLayer.mrc as #1, grid size 500,500,500, pixel 1.21, shown at level
9e-05, step 2, values float32  

> volume #1 level 0.0614 step 1

> surface dust #1 size 12.1

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J447_004_volume_map_sharp.mrc"

Opened cryosparc_P43_J447_004_volume_map_sharp.mrc as #2, grid size
500,500,500, pixel 1.21, shown at level 0.141, step 2, values float32  

> ui tool show "Volume Viewer"

> volume #2 level 0.2411

> volume #2 step 1

> volume #2 level 0.386

> volume #2 level 0.4222

> combine #2

No structures specified  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J447_004_volume_map_sharp.mrc"

Opened cryosparc_P43_J447_004_volume_map_sharp.mrc as #3, grid size
500,500,500, pixel 1.21, shown at level 0.141, step 2, values float32  

> volume #3 step 1

> volume #3 level 0.422

> hide #!1 models

> show #!1 models

> select #3

2 models selected  

> ui mousemode right "translate selected models"

> view matrix models #3,1,0,0,25.967,0,1,0,-74.508,0,0,1,54.481

> ui mousemode right "rotate selected models"

> view matrix models
> #3,0.96347,0.21584,-0.15855,17.961,0.11114,-0.86087,-0.49654,586.03,-0.24367,0.46078,-0.85341,518.26

> undo

> view matrix models
> #3,0.79666,0.53908,-0.27336,3.7392,0.30967,0.024356,0.95053,-147.33,0.51907,-0.8419,-0.14754,479.71

> view matrix models
> #3,0.41525,0.8748,0.24958,-133.48,0.82548,-0.47763,0.30074,36.066,0.38229,0.081143,-0.92047,466.87

> view matrix models
> #3,0.92112,0.382,-0.074955,-42.746,0.3655,-0.91493,-0.17121,434.82,-0.13398,0.13031,-0.98238,620.91

> view matrix models
> #3,0.77637,0.50102,-0.38241,52.076,0.39703,-0.85997,-0.32065,451.97,-0.48951,0.097114,-0.86657,701.63

> ui mousemode right "move picked models"

> view matrix models
> #3,0.77637,0.50102,-0.38241,25.472,0.39703,-0.85997,-0.32065,553.28,-0.48951,0.097114,-0.86657,791.74

> view matrix models
> #3,0.77637,0.50102,-0.38241,48.552,0.39703,-0.85997,-0.32065,561.62,-0.48951,0.097114,-0.86657,784.76

> view matrix models
> #3,0.77637,0.50102,-0.38241,47.648,0.39703,-0.85997,-0.32065,558.97,-0.48951,0.097114,-0.86657,777.13

> ui mousemode right "rotate selected models"

> view matrix models
> #3,0.77258,0.48635,-0.40815,60.448,0.42424,-0.8737,-0.23805,531.51,-0.47237,0.01076,-0.88133,801.91

> ui mousemode right "translate selected atoms"

> ui mousemode right "translate selected models"

> undo

> redo

> view matrix models
> #3,0.77258,0.48635,-0.40815,60.729,0.42424,-0.8737,-0.23805,519.64,-0.47237,0.01076,-0.88133,788.01

> ui mousemode right "rotate selected models"

> view matrix models
> #3,0.7692,0.46542,-0.43784,76.393,0.45541,-0.87994,-0.1353,483.05,-0.44825,-0.095323,-0.88881,814.52

> ui mousemode right "translate selected models"

> view matrix models
> #3,0.7692,0.46542,-0.43784,78.867,0.45541,-0.87994,-0.1353,475.67,-0.44825,-0.095323,-0.88881,816.66

> ui mousemode right "rotate selected models"

> view matrix models
> #3,0.76763,0.44829,-0.45801,90.16,0.47641,-0.87717,-0.060079,447.23,-0.42869,-0.17208,-0.88691,833.14

> view matrix models
> #3,0.72786,0.50151,-0.46766,88.772,0.53068,-0.84388,-0.079009,426.91,-0.43427,-0.19067,-0.88037,838.41

> ui mousemode right "translate selected models"

> view matrix models
> #3,0.72786,0.50151,-0.46766,91.256,0.53068,-0.84388,-0.079009,427.89,-0.43427,-0.19067,-0.88037,834.48

> view matrix models
> #3,0.72786,0.50151,-0.46766,91.452,0.53068,-0.84388,-0.079009,427.05,-0.43427,-0.19067,-0.88037,836.48

> fitmap #3 inMap #2

Fit map cryosparc_P43_J447_004_volume_map_sharp.mrc in map
cryosparc_P43_J447_004_volume_map_sharp.mrc using 105968 points  
correlation = 0.4206, correlation about mean = 0.08093, overlap = 5552  
steps = 192, shift = 2.67, angle = 3.86 degrees  
  
Position of cryosparc_P43_J447_004_volume_map_sharp.mrc (#3) relative to
cryosparc_P43_J447_004_volume_map_sharp.mrc (#2) coordinates:  
Matrix rotation and translation  
0.70495300 0.54639925 -0.45220476 78.64226718  
0.58474847 -0.80857250 -0.06541996 397.75796400  
-0.40138574 -0.21830804 -0.88951173 840.41486088  
Axis -0.92315911 -0.30685216 0.23155781  
Axis point 0.00000000 204.68777447 421.13573001  
Rotation angle (degrees) 175.25006938  
Shift along axis -0.04758910  
  

> select clear

> hide #!1 models

> select #3

2 models selected  

> view matrix models
> #3,0.70495,0.5464,-0.4522,94.095,0.58475,-0.80857,-0.06542,382.42,-0.40139,-0.21831,-0.88951,915.39

> ui mousemode right "rotate selected models"

> view matrix models
> #3,0.73095,0.52721,-0.43331,86.787,0.60816,-0.7913,0.063135,333.76,-0.30959,-0.30967,-0.89903,918.34

> view matrix models
> #3,0.74706,0.51616,-0.41891,81.241,0.61655,-0.7736,0.14634,302.31,-0.24854,-0.3676,-0.89616,916.83

> view matrix models
> #3,0.84605,0.51148,-0.15029,-22.991,0.53261,-0.82307,0.19717,327,-0.022852,-0.24687,-0.96878,835.81

> view matrix models
> #3,0.86191,0.50238,-0.068814,-48.189,0.50238,-0.82764,0.25023,322.04,0.068758,-0.25025,-0.96574,809.16

> ui mousemode right "translate selected atoms"

> ui mousemode right "translate selected models"

> view matrix models
> #3,0.86191,0.50238,-0.068814,-70.521,0.50238,-0.82764,0.25023,319.92,0.068758,-0.25025,-0.96574,760.67

> view matrix models
> #3,0.86191,0.50238,-0.068814,-73.911,0.50238,-0.82764,0.25023,318.11,0.068758,-0.25025,-0.96574,779.72

> ui mousemode right "rotate selected models"

> view matrix models
> #3,0.82213,0.56703,0.050903,-115.61,0.54654,-0.81112,0.20827,312.28,0.15938,-0.1434,-0.97675,724.71

> view matrix models
> #3,0.71078,0.70337,0.0081739,-111.25,0.69421,-0.7033,0.15307,252.92,0.11342,-0.10313,-0.98818,729.48

> ui mousemode right "translate selected models"

> view matrix models
> #3,0.71078,0.70337,0.0081739,-129.07,0.69421,-0.7033,0.15307,261.92,0.11342,-0.10313,-0.98818,702.76

> ui mousemode right "rotate selected models"

> view matrix models
> #3,0.77057,0.63617,0.038746,-135.37,0.63611,-0.77144,0.015606,338.34,0.039819,0.012621,-0.99913,693.12

> ui mousemode right "translate selected models"

> view matrix models
> #3,0.77057,0.63617,0.038746,-132.87,0.63611,-0.77144,0.015606,340.39,0.039819,0.012621,-0.99913,714.15

> view matrix models
> #3,0.77057,0.63617,0.038746,-134.68,0.63611,-0.77144,0.015606,340.23,0.039819,0.012621,-0.99913,711.19

> view matrix models
> #3,0.77057,0.63617,0.038746,-134.98,0.63611,-0.77144,0.015606,340.2,0.039819,0.012621,-0.99913,710.77

> fitmap #3 inMap #2

Fit map cryosparc_P43_J447_004_volume_map_sharp.mrc in map
cryosparc_P43_J447_004_volume_map_sharp.mrc using 105968 points  
correlation = 0.8071, correlation about mean = 0.2903, overlap = 2.137e+04  
steps = 216, shift = 14.3, angle = 12.5 degrees  
  
Position of cryosparc_P43_J447_004_volume_map_sharp.mrc (#3) relative to
cryosparc_P43_J447_004_volume_map_sharp.mrc (#2) coordinates:  
Matrix rotation and translation  
0.75695655 0.63234719 -0.16478417 -60.47340925  
0.63240914 -0.77238923 -0.05893719 369.54862535  
-0.16454628 -0.05959813 -0.98456722 774.04954826  
Axis -0.93727259 -0.33734815 0.08784255  
Axis point 0.00000000 195.73006534 384.15619129  
Rotation angle (degrees) 179.97979811  
Shift along axis 0.00800704  
  

> show #!1 models

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp.mrc"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #4, grid size
500,500,500, pixel 1.21, shown at level 0.118, step 2, values float32  

> volume #4 step 1

> volume #4 level 0.1273

> volume #4 level 0.2123

> volume #4 level 0.3541

> volume #4 level 0.3966

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/F1ATPsynthase/cryosparc_P43_J497_map_sharp_Zflipped.mrc"

Opened cryosparc_P43_J497_map_sharp_Zflipped.mrc as #5, grid size 270,270,270,
pixel 1.38, shown at level 0.00314, step 2, values float32  

> volume #5 step 1

> volume #5 level 0.3502

> select clear

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/CV-Full/cryosparc_P31_J281_004_volume_map_sharp--VC-
> Conf1.mrc"

Opened cryosparc_P31_J281_004_volume_map_sharp--VC-Conf1.mrc as #6, grid size
500,500,500, pixel 1.16, shown at level 0.0804, step 2, values float32  

> volume #6 step 1

> volume #6 level 0.4589

> hide #!5 models

> hide #!4 models

> hide #!3 models

> hide #!2 models

> volume #6 level 0.3021

> close #6

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/F1ATPsynthase/cryosparc_P31_J253_004_volume_map_sharp_Zflipped.mrc"

Opened cryosparc_P31_J253_004_volume_map_sharp_Zflipped.mrc as #6, grid size
290,290,290, pixel 1.16, shown at level 0.174, step 2, values float32  

> volume #6 level 0.4743

> volume #6 step 1

> close #6

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/ATPsynthasedimer/cryosparc_P43_J459_005_volume_map_sharp_Zflipped.mrc"

Opened cryosparc_P43_J459_005_volume_map_sharp_Zflipped.mrc as #6, grid size
500,500,500, pixel 1.21, shown at level 0.163, step 2, values float32  

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/ATPsynthasedimer/cryosparc_P43_J460_map_sharp-
> EMHanced_Zflipped.mrc"

Opened cryosparc_P43_J460_map_sharp-EMHanced_Zflipped.mrc as #7, grid size
500,500,500, pixel 1.21, shown at level 0.000886, step 2, values float32  

> volume #6 step 1

> volume #7 step 1

> volume #7 level 0.171

> volume #6 level 0.2657

> volume #7 level 0.1876

> volume #7 level 0.337

> volume #6 level 0.7439

> close #6

> close #7

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/CV-Full/cryosparc_P31_J281_004_volume_map_sharp--VC-
> Conf1.mrc"

Opened cryosparc_P31_J281_004_volume_map_sharp--VC-Conf1.mrc as #6, grid size
500,500,500, pixel 1.16, shown at level 0.0804, step 2, values float32  

> volume #6 step 1

> volume #6 level 0.2534

> volume #6 level 0.2264

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/CV-Full/cryosparc_P31_J282_005_volume_map_sharp--CV-
> Conf2.mrc"

Opened cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc as #7, grid size
500,500,500, pixel 1.16, shown at level 0.0834, step 2, values float32  

> volume #7 step 1

> volume #7 level 0.227

> volume #7 level 0.2114

> show #!5 models

> hide #!5 models

> show #!5 models

> close #5

> hide #!7 models

> show #!3 models

> show #!2 models

> volume #4 level 0.1685

> show #!6 models

> hide #!6 models

> show #!7 models

> hide #!3 models

> hide #!2 models

> hide #!4 models

> show #!4 models

> select #7

2 models selected  

> view matrix models #7,1,0,0,12.131,0,1,0,-91.07,0,0,1,-140.96

> ui mousemode right "rotate selected models"

> view matrix models
> #7,0.82248,-0.34893,-0.44918,315.63,0.55681,0.65514,0.51064,-320.52,0.1161,-0.6701,0.73313,111.48

> ui mousemode right "move picked models"

> view matrix models
> #7,0.82248,-0.34893,-0.44918,334.69,0.55681,0.65514,0.51064,-280.49,0.1161,-0.6701,0.73313,141.94

> view matrix models #4,1,0,0,0.56364,0,1,0,0.75168,0,0,1,-1.0537

> fitmap #7 inMap #4

Fit map cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc in map
cryosparc_P43_J450_008_volume_map_sharp.mrc using 192946 points  
correlation = 0.6694, correlation about mean = 0.0529, overlap = 5747  
steps = 448, shift = 21.3, angle = 14.3 degrees  
  
Position of cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc (#7)
relative to cryosparc_P43_J450_008_volume_map_sharp.mrc (#4) coordinates:  
Matrix rotation and translation  
0.74949281 -0.45315914 -0.48260471 396.43284842  
0.62339907 0.72844591 0.28414809 -236.07059316  
0.22278713 -0.51382228 0.82846397 43.83383750  
Axis -0.52693276 -0.46579934 0.71089581  
Axis point 625.45642796 450.26334447 0.00000000  
Rotation angle (degrees) 49.21659294  
Shift along axis -67.77063796  
  

> hide #!4 models

> show #!4 models

> hide #!4 models

> volume #7 level 0.2301

> show #!4 models

> volume #4 level 0.4013

> volume #7 level 0.1708

> volume #4 level 0.3314

> ui mousemode right "rotate selected models"

> view matrix models
> #7,0.73981,-0.48272,-0.46868,404.55,0.63927,0.72154,0.26592,-232.91,0.20981,-0.49634,0.84239,37.649

> view matrix models
> #7,0.34084,-0.49781,-0.7975,620.54,0.93965,0.2072,0.27226,-174.83,0.029704,-0.84217,0.53839,277.48

> view matrix models
> #7,0.13127,-0.40136,-0.90646,685.71,0.91816,-0.29558,0.26384,-19.973,-0.37383,-0.86692,0.32972,463.79

> ui mousemode right "translate selected models"

> view matrix models
> #7,0.13127,-0.40136,-0.90646,687.33,0.91816,-0.29558,0.26384,9.6358,-0.37383,-0.86692,0.32972,484.21

> fitmap #7 inMap #4

Fit map cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc in map
cryosparc_P43_J450_008_volume_map_sharp.mrc using 281244 points  
correlation = 0.6359, correlation about mean = -0.08187, overlap = 1.055e+04  
steps = 340, shift = 34.5, angle = 18.1 degrees  
  
Position of cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc (#7)
relative to cryosparc_P43_J450_008_volume_map_sharp.mrc (#4) coordinates:  
Matrix rotation and translation  
0.20417158 -0.63912338 -0.74150877 678.04765959  
0.84071522 -0.27357227 0.46728590 -57.13486252  
-0.50150959 -0.71880422 0.48146507 407.83172779  
Axis -0.62045988 -0.12554684 0.77412371  
Axis point 535.58044638 299.04488771 0.00000000  
Rotation angle (degrees) 107.09565300  
Shift along axis -97.81605804  
  

> show #!1 models

> show #!2 models

> show #!3 models

> show #!6 models

> hide #!6 models

> volume #7 level 0.2114

> ui mousemode right zoom

> ui mousemode right translate

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/CV-Full/cryosparc_P31_J281_004_volume_map_sharp--VC-
> Conf1.mrc"

Opened cryosparc_P31_J281_004_volume_map_sharp--VC-Conf1.mrc as #5, grid size
500,500,500, pixel 1.16, shown at level 0.0804, step 2, values float32  

> volume #5 level 0.1683

> volume #5 step 1

> select #4

2 models selected  

> show #!6 models

> hide #!6 models

> show #!6 models

> select #5

2 models selected  

> ui mousemode right "translate selected models"

> view matrix models #5,1,0,0,70.923,0,1,0,96.436,0,0,1,276.93

> volume #5 level 0.2711

> volume #5 level 0.3603

> close #5

> close #6

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/CV-Full/cryosparc_P31_J282_005_volume_map_sharp--CV-
> Conf2.mrc"

Opened cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc as #5, grid size
500,500,500, pixel 1.16, shown at level 0.0834, step 2, values float32  

> volume #5 step 1

> volume #5 level 0.1975

> select #5

2 models selected  

> view matrix models #5,1,0,0,64.833,0,1,0,4.8039,0,0,1,369.26

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J450_008_volume_map_sharp.mrc"

Opened cryosparc_P43_J450_008_volume_map_sharp.mrc as #6, grid size
500,500,500, pixel 1.21, shown at level 0.118, step 2, values float32  

> select #6

2 models selected  

> volume #6 step 1

> volume #6 level 0.2123

> ui mousemode right "rotate selected models"

> view matrix models
> #6,0.86316,0.45836,-0.2118,-30.342,0.47569,-0.87885,0.036716,412.65,-0.16931,-0.13244,-0.97662,715.28

> ui mousemode right "translate selected models"

> view matrix models
> #6,0.86316,0.45836,-0.2118,-24.375,0.47569,-0.87885,0.036716,423.76,-0.16931,-0.13244,-0.97662,800.74

> ui mousemode right "rotate selected models"

> view matrix models
> #6,0.86496,0.45863,-0.2037,-27.555,0.45628,-0.88773,-0.061243,463.19,-0.20892,-0.039971,-0.97712,784.83

> hide #!6 models

> show #!6 models

> hide #!4 models

> show #!4 models

> hide #!5 models

> show #!5 models

> hide #!3 models

> show #!3 models

> fitmap #6 inMap #3

Fit map cryosparc_P43_J450_008_volume_map_sharp.mrc in map
cryosparc_P43_J447_004_volume_map_sharp.mrc using 221510 points  
correlation = 0.714, correlation about mean = 0.05245, overlap = 1.496e+04  
steps = 248, shift = 10.1, angle = 12.2 degrees  
  
Position of cryosparc_P43_J450_008_volume_map_sharp.mrc (#6) relative to
cryosparc_P43_J447_004_volume_map_sharp.mrc (#3) coordinates:  
Matrix rotation and translation  
0.99999418 -0.00128579 0.00313164 -0.29910969  
0.00127502 0.99999317 0.00344053 -1.58796252  
-0.00313605 -0.00343652 0.99998907 2.03625929  
Axis -0.71259782 0.64945647 0.26535003  
Axis point 0.00000000 612.69668537 410.29613482  
Rotation angle (degrees) 0.27647278  
Shift along axis -0.27784615  
  

> hide #!7 models

> hide #!6 models

> show #!6 models

> hide #!5 models

> hide #!4 models

> hide #!3 models

> show #!3 models

> hide #!2 models

> hide #!1 models

> view matrix models
> #6,0.74923,0.61838,-0.23718,-30.94,0.60241,-0.7851,-0.14397,409.47,-0.27524,-0.035008,-0.96074,791.9

> ui mousemode right "translate selected models"

> view matrix models
> #6,0.74923,0.61838,-0.23718,-32.626,0.60241,-0.7851,-0.14397,410.01,-0.27524,-0.035008,-0.96074,784.28

> ui mousemode right "rotate selected models"

> view matrix models
> #6,0.75339,0.62751,-0.19656,-49.454,0.61874,-0.77769,-0.11119,392.56,-0.22263,-0.037853,-0.97417,773.75

> fitmap #6 inMap #3

Fit map cryosparc_P43_J450_008_volume_map_sharp.mrc in map
cryosparc_P43_J447_004_volume_map_sharp.mrc using 221510 points  
correlation = 0.7141, correlation about mean = 0.05247, overlap = 1.496e+04  
steps = 128, shift = 8.08, angle = 3.71 degrees  
  
Position of cryosparc_P43_J450_008_volume_map_sharp.mrc (#6) relative to
cryosparc_P43_J447_004_volume_map_sharp.mrc (#3) coordinates:  
Matrix rotation and translation  
0.99999418 -0.00127223 0.00313848 -0.30333720  
0.00126145 0.99999319 0.00344021 -1.58259177  
-0.00314285 -0.00343624 0.99998905 2.03895294  
Axis -0.71244109 0.65078339 0.26250460  
Axis point 0.00000000 613.36055411 408.52504306  
Rotation angle (degrees) 0.27650932  
Shift along axis -0.27858001  
  

> show #!7 models

> select #7

2 models selected  

> ui mousemode right "translate selected models"

> view matrix models
> #7,0.20417,-0.63912,-0.74151,602.47,0.84072,-0.27357,0.46729,134.32,-0.50151,-0.7188,0.48147,843.12

> ui mousemode right "rotate selected models"

> view matrix models
> #7,0.96834,0.10523,-0.22638,-16.543,0.091003,-0.99321,-0.072431,749.6,-0.23247,0.049536,-0.97134,1004.4

> view matrix models
> #7,0.93499,-0.065573,-0.34856,84.248,-0.042069,-0.99633,0.074586,742.65,-0.35217,-0.055074,-0.93432,1059.6

> view matrix models
> #7,0.65701,-0.29226,-0.69493,347.87,-0.51928,-0.84369,-0.13612,908.37,-0.54652,0.4503,-0.70608,892.4

> view matrix models
> #7,0.69516,-0.52849,-0.48729,339.7,-0.63963,-0.14541,-0.7548,936.37,0.32805,0.83639,-0.43912,428.13

> ui mousemode right "translate selected models"

> view matrix models
> #7,0.69516,-0.52849,-0.48729,311.8,-0.63963,-0.14541,-0.7548,801.93,0.32805,0.83639,-0.43912,368.2

> view matrix models
> #7,0.69516,-0.52849,-0.48729,409.44,-0.63963,-0.14541,-0.7548,780.45,0.32805,0.83639,-0.43912,326

> view matrix models
> #7,0.69516,-0.52849,-0.48729,387.59,-0.63963,-0.14541,-0.7548,816.92,0.32805,0.83639,-0.43912,309

> view matrix models
> #7,0.69516,-0.52849,-0.48729,393.89,-0.63963,-0.14541,-0.7548,811.8,0.32805,0.83639,-0.43912,311.95

> ui mousemode right "rotate selected models"

> view matrix models
> #7,0.52227,-0.69327,-0.49659,498.03,-0.59514,0.12076,-0.7945,731.7,0.61077,0.71049,-0.34952,235.83

> view matrix models
> #7,0.59283,-0.71182,-0.37666,443.49,-0.46012,0.084473,-0.88383,731.12,0.66094,0.69727,-0.27745,201.35

> ui mousemode right "translate selected models"

> view matrix models
> #7,0.59283,-0.71182,-0.37666,452.99,-0.46012,0.084473,-0.88383,746.94,0.66094,0.69727,-0.27745,198.5

> view matrix models
> #7,0.59283,-0.71182,-0.37666,448,-0.46012,0.084473,-0.88383,745.59,0.66094,0.69727,-0.27745,198.11

> view matrix models
> #7,0.59283,-0.71182,-0.37666,449.18,-0.46012,0.084473,-0.88383,746.59,0.66094,0.69727,-0.27745,193.46

> hide #!6 models

> show #!6 models

> fitmap #7 inMap #6

Fit map cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc in map
cryosparc_P43_J450_008_volume_map_sharp.mrc using 192946 points  
correlation = 0.6696, correlation about mean = -0.1143, overlap = 8244  
steps = 240, shift = 12.7, angle = 18.4 degrees  
  
Position of cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc (#7)
relative to cryosparc_P43_J450_008_volume_map_sharp.mrc (#6) coordinates:  
Matrix rotation and translation  
0.20312660 -0.64110921 -0.74008022 678.37340089  
0.84039152 -0.27372523 0.46777853 -57.22143882  
-0.50247571 -0.71697535 0.48318182 406.92766566  
Axis -0.61970912 -0.12428377 0.77492848  
Axis point 534.97941779 298.49297001 0.00000000  
Rotation angle (degrees) 107.08010281  
Shift along axis -97.94265212  
  

> ui mousemode right "rotate selected models"

> view matrix models
> #7,0.80615,-0.51629,-0.28909,312.98,-0.47941,-0.28351,-0.83054,846.23,0.34684,0.80813,-0.47606,320.82

> ui mousemode right "translate selected models"

> view matrix models
> #7,0.80615,-0.51629,-0.28909,314,-0.47941,-0.28351,-0.83054,842.31,0.34684,0.80813,-0.47606,318.18

> fitmap #7 inMap #6

Fit map cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc in map
cryosparc_P43_J450_008_volume_map_sharp.mrc using 192946 points  
correlation = 0.6695, correlation about mean = -0.1143, overlap = 8244  
steps = 136, shift = 4.52, angle = 7.86 degrees  
  
Position of cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc (#7)
relative to cryosparc_P43_J450_008_volume_map_sharp.mrc (#6) coordinates:  
Matrix rotation and translation  
0.20319129 -0.64113789 -0.74003761 678.34926801  
0.84034988 -0.27370815 0.46786332 -57.23537821  
-0.50251919 -0.71695621 0.48316499 406.94002707  
Axis -0.61973700 -0.12423744 0.77491362  
Axis point 534.98910619 298.47836436 0.00000000  
Rotation angle (degrees) 107.07815610  
Shift along axis -97.94399324  
  

> volume #6 level 0.3116

> volume #6 level 0.3399

> volume #7 level 0.2178

> volume #3 level 0.4595

> show #!5 models

> show #!4 models

> show #!2 models

> show #!1 models

> hide #!5 models

> show #!5 models

> undo

[Repeated 9 time(s)]

> redo

[Repeated 9 time(s)]

> select #7

3 models selected  

> select #5

2 models selected  

> view matrix models #5,1,0,0,37.731,0,1,0,22.534,0,0,1,-287.61

> hide #!4 models

> show #!4 models

> volume #6 level 0.331

> hide #!5 models

> show #!5 models

> hide #!6 models

> hide #!4 models

> show #!4 models

> hide #!5 models

> show #!5 models

> hide #!7 models

> hide #!3 models

> hide #!2 models

> hide #!1 models

> view matrix models #5,1,0,0,-6.9004,0,1,0,0.27774,0,0,1,-157.75

> ui mousemode right "rotate selected models"

> view matrix models
> #5,0.81449,-0.095544,-0.57226,232.73,-0.092415,0.95239,-0.29055,121.22,0.57277,0.28953,0.76688,-325.96

> view matrix models
> #5,0.74591,-0.34675,-0.56867,313.53,0.17663,0.92621,-0.33308,63.341,0.6422,0.148,0.75212,-306.38

> ui mousemode right "translate selected models"

> view matrix models
> #5,0.74591,-0.34675,-0.56867,371.86,0.17663,0.92621,-0.33308,93.059,0.6422,0.148,0.75212,-244.44

> view matrix models
> #5,0.74591,-0.34675,-0.56867,420.05,0.17663,0.92621,-0.33308,-16.769,0.6422,0.148,0.75212,-307.58

> ui mousemode right "rotate selected models"

> view matrix models
> #5,0.21468,-0.5565,-0.80263,689.85,0.97618,0.14858,0.15808,-191.22,0.031279,-0.81745,0.57515,156.12

> ui mousemode right "translate selected models"

> view matrix models
> #5,0.21468,-0.5565,-0.80263,698.48,0.97618,0.14858,0.15808,-97.393,0.031279,-0.81745,0.57515,251.95

> view matrix models
> #5,0.21468,-0.5565,-0.80263,678.12,0.97618,0.14858,0.15808,-91.44,0.031279,-0.81745,0.57515,265.51

> ui mousemode right "rotate selected models"

> view matrix models
> #5,-0.087295,-0.063242,-0.99417,696.22,0.93149,-0.35895,-0.058958,109.08,-0.35313,-0.93121,0.090244,541.3

> ui mousemode right "translate selected models"

> view matrix models
> #5,-0.087295,-0.063242,-0.99417,670.32,0.93149,-0.35895,-0.058958,157.63,-0.35313,-0.93121,0.090244,577.07

> volume #5 level 0.2197

> view matrix models
> #5,-0.087295,-0.063242,-0.99417,593.99,0.93149,-0.35895,-0.058958,296.36,-0.35313,-0.93121,0.090244,517.77

> view matrix models
> #5,-0.087295,-0.063242,-0.99417,625.31,0.93149,-0.35895,-0.058958,194.28,-0.35313,-0.93121,0.090244,564.23

> ui mousemode right "rotate selected models"

> view matrix models
> #5,0.20527,-0.55257,-0.80779,623.56,0.68046,-0.51265,0.5236,126.33,-0.70344,-0.65715,0.27077,528.56

> ui mousemode right "translate selected models"

> view matrix models
> #5,0.20527,-0.55257,-0.80779,630.67,0.68046,-0.51265,0.5236,41.913,-0.70344,-0.65715,0.27077,543.15

> ui mousemode right "rotate selected models"

> view matrix models
> #5,0.1695,-0.60205,-0.78026,647.25,0.89148,-0.24386,0.38183,-55.728,-0.42016,-0.76031,0.49538,416.19

> ui mousemode right "translate selected models"

> view matrix models
> #5,0.1695,-0.60205,-0.78026,683.96,0.89148,-0.24386,0.38183,-45.575,-0.42016,-0.76031,0.49538,398.38

> view matrix models
> #5,0.1695,-0.60205,-0.78026,686.98,0.89148,-0.24386,0.38183,-43.945,-0.42016,-0.76031,0.49538,391.52

> fitmap #5 inMap #4

Fit map cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc in map
cryosparc_P43_J450_008_volume_map_sharp.mrc using 179766 points  
correlation = 0.678, correlation about mean = -0.1153, overlap = 7826  
steps = 168, shift = 11.7, angle = 6.31 degrees  
  
Position of cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc (#5)
relative to cryosparc_P43_J450_008_volume_map_sharp.mrc (#4) coordinates:  
Matrix rotation and translation  
0.20298555 -0.64196204 -0.73937920 678.42792536  
0.84023995 -0.27352886 0.46816534 -57.38104789  
-0.50278593 -0.71628674 0.48387974 406.55778158  
Axis -0.61947637 -0.12373987 0.77520157  
Axis point 534.79686498 298.26528894 0.00000000  
Rotation angle (degrees) 107.05753086  
Shift along axis -98.00551600  
  

> show #!3 models

> show #!2 models

> show #!1 models

> show #!6 models

> show #!7 models

> hide #!6 models

> hide #!5 models

> hide #!4 models

> hide #!3 models

> hide #!2 models

> hide #!1 models

> show #!1 models

> hide #!7 models

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J436_002_volume_map_sharp_NOSEQ/lipidLayer/lipidLayer.mrc"

Opened lipidLayer.mrc as #8, grid size 500,500,500, pixel 1.21, shown at level
9e-05, step 2, values float32  

> volume #8 level 0.0614 step 1

> surface dust #8 size 12.1

> saelect #8

Unknown command: saelect #8  

> select #8

2 models selected  

> view matrix models #8,1,0,0,8.9036,0,1,0,123.29,0,0,1,230.69

> ui mousemode right "rotate selected models"

> view matrix models
> #8,0.51648,0.74645,-0.4196,47.247,0.71151,-0.64674,-0.27474,501.2,-0.47645,-0.15665,-0.86513,975.18

> ui mousemode right "translate selected models"

> view matrix models
> #8,0.51648,0.74645,-0.4196,66.848,0.71151,-0.64674,-0.27474,382.75,-0.47645,-0.15665,-0.86513,848.69

> show #!2 models

> hide #!2 models

> show #!2 models

> ui mousemode right "rotate selected models"

> view matrix models
> #8,0.8511,0.41466,-0.32202,43.997,0.39896,-0.90951,-0.11672,498.6,-0.34128,-0.029127,-0.93951,796.29

> view matrix models
> #8,0.7599,0.59375,-0.26459,-1.6871,0.59539,-0.79911,-0.083268,401.69,-0.26088,-0.09426,-0.96076,800.05

> ui mousemode right "translate selected models"

> view matrix models
> #8,0.7599,0.59375,-0.26459,-16.725,0.59539,-0.79911,-0.083268,396.61,-0.26088,-0.09426,-0.96076,799.17

> fitmap #8 inMap #1

Fit map lipidLayer.mrc in map lipidLayer.mrc using 472796 points  
correlation = 0.6805, correlation about mean = 0.5513, overlap = 8188  
steps = 276, shift = 4.17, angle = 6 degrees  
  
Position of lipidLayer.mrc (#8) relative to lipidLayer.mrc (#1) coordinates:  
Matrix rotation and translation  
0.75849569 0.62889167 -0.17081965 -57.74503051  
0.62888068 -0.77509304 -0.06115366 372.28139318  
-0.17086017 -0.06104040 -0.98340265 775.82372383  
Axis 0.93765443 0.33544803 -0.09098785  
Axis point 0.00000000 196.45741231 385.11613292  
Rotation angle (degrees) 179.99653959  
Shift along axis 0.14564814  
  

> hide #!1 models

> show #!1 models

> hide #!2 models

> vop add #8 to #1

> volume add #8 to #1

Expected a keyword  

> vop add #8,1 onGrid #1

Opened volume sum as #9, grid size 500,500,500, pixel 1.21, shown at step 1,
values float32  

> volume #9 level 0.08976

> surface dust #9 size 12.1

> show #!6 models

> show #!7 models

> show #!5 models

> show #!4 models

> show #!3 models

> show #!2 models

> show #!1 models

> hide #!1 models

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J246_007_volume_map_sharp_Zflip/superComplexConsolidatedV8.cif"

Summary of feedback from opening
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J246_007_volume_map_sharp_Zflip/superComplexConsolidatedV8.cif  
---  
warnings | Unknown polymer entity '1' on line 2257  
Unknown polymer entity '2' on line 7589  
Unknown polymer entity '3' on line 14908  
Unknown polymer entity '4' on line 17767  
Unknown polymer entity '5' on line 26028  
59 messages similar to the above omitted  
Atom H5' is not in the residue template for ATP /AU:2000  
Atom H5' is not in the residue template for ATP /E:2000  
Atom H61 is not in the residue template for LPP /I0:1000  
Atom HO1 is not in the residue template for CDL /JJ:2000  
Atom HO1 is not in the residue template for CDL /Jw:1000  
Atom H3 is not in the residue template for 3PE /LG:1000  
Atom H3 is not in the residue template for 3PE /LO:1000  
Atom H61 is not in the residue template for LPP /LY:1000  
Atom H3 is not in the residue template for 3PE /Np:1001  
Too many hydrogens missing from residue template(s) to warn about  
Atom OMA is not in the residue template for HEM /HM:1  
Atom C13 is not in the residue template for HE9 /HM:1  
Missing or incomplete sequence information. Inferred polymer connectivity.  
  
  
Chain information for superComplexConsolidatedV8.cif #10  
---  
Chain | Description  
A | No description available  
A0 | No description available  
AG t3 | No description available  
AU | No description available  
Ab | No description available  
Aj | No description available  
Aq | No description available  
Ar t4 | No description available  
B | No description available  
BI | No description available  
BK | No description available  
BP | No description available  
C | No description available  
C0 C1 C2 C3 C5 C6 C7 C8 C9 | No description available  
C4 | No description available  
D | No description available  
D6 | No description available  
E | No description available  
E1 | No description available  
E4 | No description available  
Ek | No description available  
Eq | No description available  
Es | No description available  
Ev | No description available  
F9 | No description available  
FF | No description available  
FH | No description available  
FL | No description available  
FO | No description available  
Fy | No description available  
Fz | No description available  
GT | No description available  
I0 tb | No description available  
IE | No description available  
IY | No description available  
Il td | No description available  
Ix t9 | No description available  
Iy tc | No description available  
J6 t1 | No description available  
JC | No description available  
JI | No description available  
JJ t6 | No description available  
JN tf | No description available  
Jw t8 | No description available  
Jx | No description available  
K5 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial  
KI t5 | No description available  
Ke | No description available  
Kp | No description available  
Ks te | No description available  
L3 | Uncharacterized protein  
LG | No description available  
LO t2 | No description available  
LR | No description available  
LY tg | No description available  
M | No description available  
Mg | No description available  
Mq | No description available  
Mr t0 | No description available  
NF | No description available  
NM | No description available  
Np t7 | No description available  
R | No description available  
TB | No description available  
Y ta | No description available  
a | No description available  
  

> hide #!10 models

> show #!10 models

> hide #!9 models

> show #!9 models

> hide #!9 models

> show #!9 models

> hide #!7 models

> hide #!6 models

> hide #!5 models

> hide #!4 models

> hide #!3 models

> hide #!2 models

> close #10

> open "/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
> rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
> Computer/supercomplex/supercomplexV-
> IV2-II/cryosparc_P43_J246_007_volume_map_sharp_Zflip/supercomplexFullV1.cif"

Summary of feedback from opening
/Users/rafaelrocha/Library/CloudStorage/GoogleDrive-
rafael.eduardo.oliveira.rocha@gmail.com/Other computers/My
Computer/supercomplex/supercomplexV-
IV2-II/cryosparc_P43_J246_007_volume_map_sharp_Zflip/supercomplexFullV1.cif  
---  
warnings | Unknown polymer entity '3' on line 16278  
Unknown polymer entity '4' on line 21610  
Unknown polymer entity '5' on line 28929  
Unknown polymer entity '6' on line 31788  
Unknown polymer entity '7' on line 40049  
59 messages similar to the above omitted  
Atom H5' is not in the residue template for ATP /AU:2000  
Atom H5' is not in the residue template for ATP /E:2000  
Atom H61 is not in the residue template for LPP /I0:1000  
Atom HO1 is not in the residue template for CDL /JJ:2000  
Atom HO1 is not in the residue template for CDL /Jw:1000  
Atom H3 is not in the residue template for 3PE /LG:1000  
Atom H3 is not in the residue template for 3PE /LO:1000  
Atom H61 is not in the residue template for LPP /LY:1000  
Atom H3 is not in the residue template for 3PE /Np:1001  
Too many hydrogens missing from residue template(s) to warn about  
Atom OMA is not in the residue template for HEM /HM:1  
Atom C13 is not in the residue template for HE9 /HP:1  
Atom C13 is not in the residue template for HE9 /HM:1  
Atom OMA is not in the residue template for HEM /HP:1  
Missing or incomplete sequence information. Inferred polymer connectivity.  
  
  
Chain information for supercomplexFullV1.cif #10  
---  
Chain | Description  
A vQ | No description available  
A0 v0 | No description available  
AG t3 | No description available  
AU v3 | No description available  
Ab v1 | No description available  
Aj v2 | No description available  
Aq v6 | No description available  
Ar t4 | No description available  
B vL | No description available  
BI v7 | No description available  
BK v5 | No description available  
BP v8 | No description available  
C vM | No description available  
C0 C1 C2 C3 C5 C6 C7 C8 C9 vB vC vD vE vG vH vI vJ vK | No description available  
C4 vF | No description available  
D vN | No description available  
D6 vh | No description available  
E v4 | No description available  
E1 vb | No description available  
E4 vd | No description available  
Ek vT | No description available  
Eq vS | No description available  
Es vR | No description available  
Ev ve | No description available  
F9 vO | No description available  
FF vP | No description available  
FH vW | No description available  
FL vZ | No description available  
FO va | No description available  
Fy vU | No description available  
Fz vV | No description available  
GT vY | No description available  
I0 tb | No description available  
IE v9 | No description available  
IY vA | No description available  
Il td | No description available  
Ix t9 | No description available  
Iy tc | No description available  
J6 t1 | No description available  
JC vg | No description available  
JI r2 | No description available  
JJ t6 | No description available  
JN tf | No description available  
Jw t8 | No description available  
Jx r8 | No description available  
K5 r1 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial  
KI t5 | No description available  
Ke r9 | No description available  
Kp r0 | No description available  
Ks te | No description available  
L3 r5 | Uncharacterized protein  
LG rB | No description available  
LO t2 | No description available  
LR r7 | No description available  
LY tg | No description available  
M r6 | No description available  
Mg rD | No description available  
Mq rA | No description available  
Mr t0 | No description available  
NF r3 | No description available  
NM r4 | No description available  
Np t7 | No description available  
R vf | No description available  
TB rC | No description available  
Y ta | No description available  
a vX | No description available  
  

> hide atoms

> show cartoons

> color #10/Kp,K5,JI,NF,NM,L3,M,LR,Jx,Ke,Mq,LG,TB,Mg lightgreen

> color #10/r0,r1,r2,r3,r4,r5,r6,r7,r8,r9,rA,rB,rC,rD springgreen

> color #10/Av,lx,Mr,LY,LO,Np,AG,KI,Ar,Jw,JN,J6,Y,JJ,Il,Iy,I0,Ks,Ix darkred

> color #10/AV,t9,t0,tg,t2,t7,t3,t5,t4,t8,tf,t1,ta,t6,td,tc,tb,te
> palevioletred

> color
> #10/A0,Ab,Aj,AU,E,BK,Aq,BI,BP,IE,IY,C0,C1,C2,C3,C4,C5,C6,C7,C8,C9,B,C,D,F9,FF,A,Es,Eq,Ek,Fy,Fz,FH,a,GT,FL,FO,E1,F9,E4,Ev,R,JC,D6
> darkcyan

> color
> #10/v0,v1,v2,v3,v4,v5,v6,v7,v8,v9,vA,vB,vC,vD,vE,vF,vG,vH,vI,vJ,vK,vL,vM,vN,vO,vP,vQ,vR,vS,vT,vU,vV,vW,vX,vY,vZ,va,vb,vc,vd,ve,vf,vg,vh
> cyan

> hide #!9 models

> color #10/r0,r1,r2,r3,r4,r5,r6,r7,r8,r9,rA,rB,rC,rD sea green

> color #10/r0,r1,r2,r3,r4,r5,r6,r7,r8,r9,rA,rB,rC,rD forestgreen

> color
> #10/v0,v1,v2,v3,v4,v5,v6,v7,v8,v9,vA,vB,vC,vD,vE,vF,vG,vH,vI,vJ,vK,vL,vM,vN,vO,vP,vQ,vR,vS,vT,vU,vV,vW,vX,vY,vZ,va,vb,vc,vd,ve,vf,vg,vh
> darkcyan

> color
> #10/A0,Ab,Aj,AU,E,BK,Aq,BI,BP,IE,IY,C0,C1,C2,C3,C4,C5,C6,C7,C8,C9,B,C,D,F9,FF,A,Es,Eq,Ek,Fy,Fz,FH,a,GT,FL,FO,E1,F9,E4,Ev,R,JC,D6
> cyan

> color #10/AV,t9,t0,tg,t2,t7,t3,t5,t4,t8,tf,t1,ta,t6,td,tc,tb,te darkred

> color #10/Av,lx,Mr,LY,LO,Np,AG,KI,Ar,Jw,JN,J6,Y,JJ,Il,Iy,I0,Ks,Ix pale
> violet red

> show #!9 models

> color #9 goldenrod

> transparency #9.1 50

> camera ortho

> cofr showPivot false

> lighting soft

> lighting depthCue false

> set bgColor white

> show #!1 models

> show #!2 models

> show #!3 models

> show #!4 models

> show #!5 models

> show #!6 models

> show #!7 models

> show #!8 models

> hide #!8 models

> hide #!1 models

> color zone #2-7 near #10

> hide #!10 models

> color zone #2-7 near #10 distance 10

> color zone #2-7 near #10 distance 30

> hide #!2 models

> show #!2 models

> hide #!2 models

> show #!2 models

> hide #!2 models

> show #!2 models

> volume #2 level 0.5034

> color zone #2-7 near #10 distance 0

> volume #2 level 0.2723

> hide #!3 models

> show #!3 models

> hide #!3 models

> show #!3 models

> hide #!2 models

> show #!2 models

> volume #3 level 0.4282

> volume #3 level 0.272

> hide #!5 models

> show #!5 models

> volume #5 level 0.1785

> volume #5 level 0.1848

> hide #!6 models

> show #!6 models

> volume #6 level 0.185

> undo

> volume #7 level 185

> undo

[Repeated 1 time(s)]

> redo

[Repeated 2 time(s)]

> hide #!7 models

> show #!7 models

> hide #!7 models

> show #!7 models

> volume #7 level 0.245

> volume #7 level 185

> volume #7 level 0.2228

> volume #7 level 0.1943

> volume #7 level 0.185

> hide #!4 models

> show #!4 models

> hide #!6 models

> show #!6 models

> volume #6 level 0.331

> surface dust #2-7 size 12.1

> hide #!4 models

> show #!4 models

> molmap

Missing or invalid "atoms" argument: empty atom specifier  

> molmap #10 resolution 5

Missing or invalid "resolution" argument: Expected a number  

> molmap #10 5

Opened supercomplexFullV1.cif map 5 as #11, grid size 164,207,299, pixel 1.67,
shown at level 0.111, step 1, values float32  

> close #11

> molmap #10/Av,lx,Mr,LY,LO,Np,AG,KI,Ar,Jw,JN,J6,Y,JJ,Il,Iy,I0,Ks,Ix 5

Opened supercomplexFullV1.cif map 5 as #11, grid size 119,103,83, pixel 1.67,
shown at level 0.116, step 1, values float32  

> vop

> hide #!2 models

> show #!2 models

> hide #!2 models

> hide #!3 models

> show #!3 models

> hide #!4 models

> hide #!6 models

> hide #!7 models

> hide #!9 models

> hide #!3 models

> show #!3 models

> hide #!5 models

> vop subtract #3 #11

Opened volume difference as #12, grid size 500,500,500, pixel 1.21, shown at
step 1, values float32  

> volume #12 level 0.4582

> show #!2 models

> rename #11 fakeComplexIVA

> molmap #10/AV,t9,t0,tg,t2,t7,t3,t5,t4,t8,tf,t1,ta,t6,td,tc,tb,te 5

Opened supercomplexFullV1.cif map 5 as #13, grid size 129,98,83, pixel 1.67,
shown at level 0.112, step 1, values float32  

> rename #12 fakeComplexIVB

> hide #!2 models

> show #!2 models

> show #!3 models

> hide #!3 models

> vop subtract #2 #12

Opened volume difference as #14, grid size 500,500,500, pixel 1.21, shown at
step 1, values float32  

> volume #14 level 0.3924

> volume #14 level 0.401

> hide #!13 models

> show #!12 models

> volume #14 level 0.272

> volume #14 level 0.3749

> volume #14 level 0.3063

> volume #12 level 0.306

> show #!4 models

> hide #!4 models

> show #!4 models

> show #!5 models

> show #!10 models

> hide #!12 models

> hide #!14 models

> hide #!5 models

> hide #!4 models

> info chains sel

chain id /A chain_id A  
chain id /C3 chain_id C3  
chain id /C4 chain_id C4  
chain id /E1 chain_id E1  
chain id /E4 chain_id E4  
chain id /Ek chain_id Ek  
chain id /Eq chain_id Eq  
chain id /Es chain_id Es  
chain id /Ev chain_id Ev  
chain id /F9 chain_id F9  
chain id /FF chain_id FF  
chain id /FH chain_id FH  
chain id /FL chain_id FL  
chain id /FO chain_id FO  
chain id /Fy chain_id Fy  
chain id /Fz chain_id Fz  
chain id /GT chain_id GT  
chain id /LR chain_id LR  
chain id /R chain_id R  
chain id /a chain_id a  
chain id /t1 chain_id t1  
chain id /ta chain_id ta  
chain id /tb chain_id tb  
chain id /tc chain_id tc  
chain id /td chain_id td  
chain id /tg chain_id tg  

> select
> #10/A,C3,C4,E1,E4,Ek,Eq,Es,Ev,F9,FF,FH,FL,FO,Fy,Fz,GT,LR,R,a,t1,ta,tb,tc,td,tg

60515 atoms, 61309 bonds, 2 pseudobonds, 3469 residues, 2 models selected  

> show #!6 models

> show #!5 models

> show #!4 models

> show #!7 models

> hide #!6 models

> hide #!7 models

> hide #!10 models

> volume #4 level 0.2333

> hide #!4 models

> ui tool show "Map Eraser"

> select #15

1 model selected  

> ui mousemode right "translate selected models"

> view matrix models #15,1,0,0,251.93,0,1,0,306.79,0,0,1,228.72

> view matrix models #15,1,0,0,224.86,0,1,0,291.43,0,0,1,244.07

> view matrix models #15,1,0,0,219.15,0,1,0,288.03,0,0,1,247.57

> show #!4 models

> hide #!4 models

> show #!4 models

> hide #!4 models

> show #!4 models

> hide #!4 models

> show #!4 models

> show #!6 models

> hide #!6 models

> show #!6 models

> hide #!6 models

> volume #4 level 0.331

> hide #!4 models

> view matrix models #15,1,0,0,214.01,0,1,0,278.94,0,0,1,249.69

> view matrix models #15,1,0,0,203.93,0,1,0,263.63,0,0,1,250.09

> view matrix models #15,1,0,0,205.46,0,1,0,264.04,0,0,1,243.7

> volume erase #5 center 205.46,264.04,243.7 radius 26.39

Opened cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc copy as #16, grid
size 500,500,500, pixel 1.16, shown at step 1, values float32  

> view matrix models #15,1,0,0,225.37,0,1,0,292.43,0,0,1,235.5

> volume erase #16 center 225.37,292.43,235.5 radius 26.39

> view matrix models #15,1,0,0,223.65,0,1,0,289.29,0,0,1,262.22

> view matrix models #15,1,0,0,219.65,0,1,0,282.04,0,0,1,273.28

> volume erase #16 center 219.65,282.04,273.28 radius 26.39

> view matrix models #15,1,0,0,259.73,0,1,0,297.14,0,0,1,261.24

> view matrix models #15,1,0,0,250.68,0,1,0,274.62,0,0,1,216.07

> view matrix models #15,1,0,0,248.31,0,1,0,275.61,0,0,1,218.05

> view matrix models #15,1,0,0,244.26,0,1,0,273.34,0,0,1,219.01

> volume erase #16 center 244.26,273.34,219.01 radius 26.39

> view matrix models #15,1,0,0,250.85,0,1,0,304.4,0,0,1,246.09

> view matrix models #15,1,0,0,250.95,0,1,0,286.74,0,0,1,249.52

> view matrix models #15,1,0,0,259.2,0,1,0,287.87,0,0,1,241.85

> view matrix models #15,1,0,0,259.23,0,1,0,287.42,0,0,1,241.84

> volume erase #16 center 259.23,287.42,241.84 radius 26.39

> view matrix models #15,1,0,0,266.27,0,1,0,296.97,0,0,1,280.79

> view matrix models #15,1,0,0,265.78,0,1,0,289.13,0,0,1,274.58

> view matrix models #15,1,0,0,271.73,0,1,0,284.05,0,0,1,275.03

> volume erase #16 center 271.73,284.05,275.03 radius 26.39

> view matrix models #15,1,0,0,274.79,0,1,0,283.17,0,0,1,263.88

> view matrix models #15,1,0,0,274.9,0,1,0,283.88,0,0,1,263.85

> view matrix models #15,1,0,0,274.88,0,1,0,285.72,0,0,1,263.92

> volume erase #16 center 274.88,285.72,263.92 radius 26.39

> view matrix models #15,1,0,0,246.41,0,1,0,285.25,0,0,1,282.45

> view matrix models #15,1,0,0,249.09,0,1,0,287.76,0,0,1,269.76

> volume erase #16 center 249.09,287.76,269.76 radius 26.39

> view matrix models #15,1,0,0,266.24,0,1,0,310.99,0,0,1,228.03

> view matrix models #15,1,0,0,255.69,0,1,0,311.64,0,0,1,231.63

> volume erase #16 center 255.69,311.64,231.63 radius 26.39

> show #!4 models

> view matrix models #15,1,0,0,304.6,0,1,0,295.09,0,0,1,220.32

> view matrix models #15,1,0,0,277.06,0,1,0,299.44,0,0,1,244.74

> view matrix models #15,1,0,0,292.27,0,1,0,298.59,0,0,1,236.39

> view matrix models #15,1,0,0,291.29,0,1,0,298.58,0,0,1,236.87

> hide #!4 models

> volume erase #16 center 291.29,298.58,236.87 radius 26.39

> view matrix models #15,1,0,0,289.43,0,1,0,293.37,0,0,1,260.33

> view matrix models #15,1,0,0,306.87,0,1,0,281.12,0,0,1,266.12

> volume erase #16 center 306.87,281.12,266.12 radius 26.39

> view matrix models #15,1,0,0,291.8,0,1,0,266.72,0,0,1,284.29

> view matrix models #15,1,0,0,285.06,0,1,0,269.74,0,0,1,287.74

> volume erase #16 center 285.06,269.74,287.74 radius 26.39

> view matrix models #15,1,0,0,282.2,0,1,0,297.97,0,0,1,232.7

> view matrix models #15,1,0,0,282.45,0,1,0,293.2,0,0,1,232.67

> view matrix models #15,1,0,0,284.09,0,1,0,290.61,0,0,1,230.55

> volume erase #16 center 284.09,290.61,230.55 radius 26.39

> view matrix models #15,1,0,0,260.13,0,1,0,308.58,0,0,1,211.48

> view matrix models #15,1,0,0,267.53,0,1,0,305.2,0,0,1,211.48

> view matrix models #15,1,0,0,269.8,0,1,0,304.44,0,0,1,205.53

> volume erase #16 center 269.8,304.44,205.53 radius 26.39

> view matrix models #15,1,0,0,243.33,0,1,0,297.59,0,0,1,201.82

> volume erase #16 center 243.33,297.59,201.82 radius 26.39

> show #!4 models

> hide #!4 models

> show #!4 models

> hide #!16 models

> show #!16 models

> show #!5 models

> hide #!5 models

> vop add #16

Opened cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc copy resampled as
#17, grid size 500,500,500, pixel 1.16, shown at step 1, values float32  

> show #!16 models

> hide #15 models

> hide #!17 models

> show #!17 models

> hide #!17 models

> show #!17 models

> hide #!16 models

> hide #!17 models

> show #!17 models

> show #!16 models

> hide #!17 models

> show #!17 models

> show #!7 models

> select #17

2 models selected  

> view matrix models
> #17,0.20299,-0.64196,-0.73938,720.88,0.84024,-0.27353,0.46817,-13.756,-0.50279,-0.71629,0.48388,617.69

> ui mousemode right "rotate selected models"

> view matrix models
> #17,0.13895,-0.65367,-0.74392,745.67,0.21861,0.75292,-0.62075,191,0.96587,-0.076371,0.24752,37.313

> view matrix models
> #17,0.35397,-0.7908,-0.49934,649.93,-0.45588,0.3203,-0.83041,580.75,0.81663,0.52158,-0.24713,51.654

> ui mousemode right "translate selected models"

> view matrix models
> #17,0.35397,-0.7908,-0.49934,636.57,-0.45588,0.3203,-0.83041,690.16,0.81663,0.52158,-0.24713,176.51

> view matrix models
> #17,0.35397,-0.7908,-0.49934,588.21,-0.45588,0.3203,-0.83041,641.57,0.81663,0.52158,-0.24713,205.62

> ui mousemode right "rotate selected models"

> view matrix models
> #17,0.78307,-0.49664,-0.37437,337.27,-0.55273,-0.27977,-0.785,825.9,0.28513,0.82163,-0.49358,357.47

> ui mousemode right "translate selected models"

> view matrix models
> #17,0.78307,-0.49664,-0.37437,331.11,-0.55273,-0.27977,-0.785,852.5,0.28513,0.82163,-0.49358,334.85

> ui mousemode right "rotate selected models"

> view matrix models
> #17,0.82938,-0.46514,-0.30946,290.37,-0.47995,-0.30969,-0.82082,847.18,0.28596,0.8293,-0.4801,328.87

> ui mousemode right "translate selected models"

> view matrix models
> #17,0.82938,-0.46514,-0.30946,293.43,-0.47995,-0.30969,-0.82082,843.84,0.28596,0.8293,-0.4801,329.17

> hide #!16 models

> show #!16 models

> fitmap #17 inMap #7

Fit map cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc copy resampled
in map cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc using 209698
points  
correlation = 1, correlation about mean = 1, overlap = 2.452e+04  
steps = 104, shift = 6.07, angle = 3.74 degrees  
  
Position of cryosparc_P31_J282_005_volume_map_sharp--CV-Conf2.mrc copy
resampled (#17) relative to cryosparc_P31_J282_005_volume_map_sharp--CV-
Conf2.mrc (#7) coordinates:  
Matrix rotation and translation  
0.99999999 0.00001502 -0.00001400 -0.00079880  
-0.00001502 0.99999999 -0.00001834 0.00851721  
0.00001401 0.00001833 1.00000000 -0.00699235  
Axis 0.66597422 -0.50879330 -0.54553434  
Axis point 0.00000000 412.65530310 435.38412340  
Rotation angle (degrees) 0.00157735  
Shift along axis -0.00105091  
  

> hide #!7 models

> hide #!4 models

> show #15 models

> hide #15 models

> show #15 models

> hide #!16 models

> show #!16 models

> show #!2 models

> show #!3 models

> hide #!3 models

> hide #!2 models

> show #!2 models

> hide #!2 models

> show #!4 models

> hide #15 models

> show #!5 models

> hide #!5 models

> show #!6 models

> show #!7 models

> hide #!7 models

> show #!8 models

> hide #!8 models

> show #!9 models

> show #!10 models

> hide #!10 models

> show #!13 models

> hide #!13 models

> show #!14 models

> hide #!14 models

> show #!14 models

> show #!13 models

> hide #!13 models

> show #!11 models

> hide #!11 models

> show #!12 models

> hide #!12 models

> show #!12 models

> hide #!12 models

> show #!12 models

> hide #!14 models

> show #!14 models

> show #!13 models

> hide #!13 models

> rename #13 fakeComplexIVB

> rename #12 volumeDifference

> surface dust #4,6,12,14,16,17 size 12.1

> hide #!17 models

> hide #!16 models

> hide #!14 models

> hide #!12 models

> hide #!9 models

> show #!9 models

> hide #!6 models

> hide #!4 models

> hide #!9 models

> show #!10 models

> select #10&ligand

11879 atoms, 11905 bonds, 78 residues, 1 model selected  

> show sel atoms

> style sel stick

Changed 11879 atom styles  

> select #10&±ligand

Expected an objects specifier or a keyword  

> select #10&~ligand

432885 atoms, 438033 bonds, 30 pseudobonds, 27212 residues, 2 models selected  

> hide sel cartoons

> select up

114 atoms, 117 bonds, 1 residue, 1 model selected  

> select up

228 atoms, 234 bonds, 3 residues, 1 model selected  

> select up

444764 atoms, 449938 bonds, 27280 residues, 1 model selected  

> select clear

> select up

114 atoms, 117 bonds, 1 residue, 1 model selected  

> color sel dark red

> select up

114 atoms, 117 bonds, 1 residue, 1 model selected  

> color sel dark red

> select up

114 atoms, 117 bonds, 1 residue, 1 model selected  

> color sel dark red

> select up

71 atoms, 74 bonds, 1 residue, 1 model selected  

> color sel dark red

> select up

43 atoms, 42 bonds, 1 residue, 1 model selected  

> color sel dark red

> select up

114 atoms, 117 bonds, 1 residue, 1 model selected  

> select up

114 atoms, 117 bonds, 1 residue, 1 model selected  

> color sel pale violet red

> select up

114 atoms, 117 bonds, 1 residue, 1 model selected  

> color sel pale violet red

> select up

114 atoms, 117 bonds, 1 residue, 1 model selected  

> color sel pale violet red

> select up

71 atoms, 74 bonds, 1 residue, 1 model selected  

> color sel pale violet red

> select #10&ligand

11879 atoms, 11905 bonds, 78 residues, 1 model selected  

> select #10&~ligand

432885 atoms, 438033 bonds, 30 pseudobonds, 27212 residues, 2 models selected  

> show sel cartoons

> hide sel cartoons

> select clear

> select up

77 atoms, 80 bonds, 1 residue, 1 model selected  

> color sel light green

> select up

7 atoms, 9 bonds, 1 residue, 1 model selected  

> color sel light green

> select up

8 atoms, 12 bonds, 1 residue, 1 model selected  

> color sel light green

> select #10&~ligand

432885 atoms, 438033 bonds, 30 pseudobonds, 27212 residues, 2 models selected  

> select clear

> select up

4 atoms, 4 bonds, 1 residue, 1 model selected  

> color sel light green

> select clear

> select up

84 atoms, 89 bonds, 1 residue, 1 model selected  

> color sel light green

> select clear

[Repeated 1 time(s)]

> select up

77 atoms, 80 bonds, 1 residue, 1 model selected  

> color sel forest green

> view matrix models #10,1,0,0,0.013167,0,1,0,-0.0035219,0,0,1,0.036517

> select up

444764 atoms, 449938 bonds, 27280 residues, 1 model selected  

> select clear

> select up

7 atoms, 9 bonds, 1 residue, 1 model selected  

> color sel forest green

[Repeated 1 time(s)]

> select up

8 atoms, 12 bonds, 1 residue, 1 model selected  

> color sel forest green

> select up

4 atoms, 4 bonds, 1 residue, 1 model selected  

> color sel forest green

> select up

84 atoms, 89 bonds, 1 residue, 1 model selected  

> color sel forest green

> select clear

> select #10&~ligand

432885 atoms, 438033 bonds, 30 pseudobonds, 27212 residues, 2 models selected  

> show sel cartoons

> show #!4 models

> show #!6 models

> hide #!10 models

> show #!12 models

> show #!14 models

> show #!16 models

> show #!17 models

> show #!9 models

> show #!10 models

> color zone #4,6,12,14,16,17 near #10 distance 30

> hide #!10 models

> show #!10 models

> hide #!10 models

> save
> /Users/rafaelrocha/supercomplex/Manuscript/figures/figureA/fullComplexMapVisualization.cxs

Taking snapshot of stepper: combination  
Traceback (most recent call last):  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/session.py", line 322, in process  
data = sm.take_snapshot(obj, session, self.state_flags)  
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/atomic/structure.py", line 1424, in take_snapshot  
'structure state': Structure.take_snapshot(self, session, flags),  
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/atomic/structure.py", line 218, in take_snapshot  
data = {'model state': Model.take_snapshot(self, session, flags),  
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/models.py", line 365, in take_snapshot  
'positions': self.positions.array(),  
^^^^^^^^^^^^^^^^^^^^  
AttributeError: 'NoneType' object has no attribute 'array'  
  
The above exception was the direct cause of the following exception:  
  
Traceback (most recent call last):  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/session.py", line 297, in discovery  
self.processed[key] = self.process(obj, parents)  
^^^^^^^^^^^^^^^^^^^^^^^^^^  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/session.py", line 329, in process  
raise RuntimeError(msg) from e  
RuntimeError: Error while saving session data for 'isolde residue stepper 2'
-> <chimerax.isolde.navigate.ResidueStepper object at 0x327233990> ->
<chimerax.atomic.structure.AtomicStructure object at 0x328337b50>
'combination'  
  
During handling of the above exception, another exception occurred:  
  
Traceback (most recent call last):  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/session.py", line 1051, in save  
session.save(output, version=version, include_maps=include_maps)  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/session.py", line 741, in save  
mgr.discovery(self._state_containers)  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/session.py", line 301, in discovery  
raise ValueError(  
ValueError: error processing: 'isolde residue stepper 2' ->
<chimerax.isolde.navigate.ResidueStepper object at 0x327233990> ->
<chimerax.atomic.structure.AtomicStructure object at 0x328337b50>
'combination': Error while saving session data for 'isolde residue stepper 2'
-> <chimerax.isolde.navigate.ResidueStepper object at 0x327233990> ->
<chimerax.atomic.structure.AtomicStructure object at 0x328337b50>
'combination'  
  
ValueError: error processing: 'isolde residue stepper 2' -> -> 'combination':
Error while saving session data for 'isolde residue stepper 2' -> ->
'combination'  
  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/session.py", line 301, in discovery  
raise ValueError(  
  
See log for complete Python traceback.  
  
Traceback (most recent call last):  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/session.py", line 322, in process  
data = sm.take_snapshot(obj, session, self.state_flags)  
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/atomic/structure.py", line 1424, in take_snapshot  
'structure state': Structure.take_snapshot(self, session, flags),  
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/atomic/structure.py", line 218, in take_snapshot  
data = {'model state': Model.take_snapshot(self, session, flags),  
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/models.py", line 365, in take_snapshot  
'positions': self.positions.array(),  
^^^^^^^^^^^^^^^^^^^^  
AttributeError: 'NoneType' object has no attribute 'array'  
  
The above exception was the direct cause of the following exception:  
  
Traceback (most recent call last):  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/session.py", line 297, in discovery  
self.processed[key] = self.process(obj, parents)  
^^^^^^^^^^^^^^^^^^^^^^^^^^  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/session.py", line 329, in process  
raise RuntimeError(msg) from e  
RuntimeError: Error while saving session data for 'isolde residue stepper 2'
-> <chimerax.isolde.navigate.ResidueStepper object at 0x327233990> ->
<chimerax.atomic.structure.AtomicStructure object at 0x328337b50>
'combination'  
  
During handling of the above exception, another exception occurred:  
  
Traceback (most recent call last):  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/save_command/dialog.py", line 127, in <lambda>  
lambda *args, ses=session: show_save_file_dialog(ses), tool_tip="Save output
file",  
^^^^^^^^^^^^^^^^^^^^^^^^^^  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/save_command/dialog.py", line 138, in show_save_file_dialog  
_dlg.display(session, **kw)  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/save_command/dialog.py", line 62, in display  
run(session, cmd)  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/commands/run.py", line 49, in run  
results = command.run(text, log=log, return_json=return_json)  
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/commands/cli.py", line 3213, in run  
result = ci.function(session, **kw_args)  
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/save_command/cmd.py", line 86, in cmd_save  
Command(session, registry=registry).run(provider_cmd_text, log=log)  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/commands/cli.py", line 3213, in run  
result = ci.function(session, **kw_args)  
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/save_command/cmd.py", line 101, in provider_save  
saver_info.save(session, path, **provider_kw)  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core_formats/__init__.py", line 95, in save  
return cxs_save(session, path, **kw)  
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/session.py", line 1051, in save  
session.save(output, version=version, include_maps=include_maps)  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/session.py", line 741, in save  
mgr.discovery(self._state_containers)  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/session.py", line 301, in discovery  
raise ValueError(  
ValueError: error processing: 'isolde residue stepper 2' ->
<chimerax.isolde.navigate.ResidueStepper object at 0x327233990> ->
<chimerax.atomic.structure.AtomicStructure object at 0x328337b50>
'combination': Error while saving session data for 'isolde residue stepper 2'
-> <chimerax.isolde.navigate.ResidueStepper object at 0x327233990> ->
<chimerax.atomic.structure.AtomicStructure object at 0x328337b50>
'combination'  
  
ValueError: error processing: 'isolde residue stepper 2' -> -> 'combination':
Error while saving session data for 'isolde residue stepper 2' -> ->
'combination'  
  
File
"/Applications/ChimeraX-1.9.app/Contents/Library/Frameworks/Python.framework/Versions/3.11/lib/python3.11/site-
packages/chimerax/core/session.py", line 301, in discovery  
raise ValueError(  
  
See log for complete Python traceback.  
  




OpenGL version: 4.1 Metal - 89.3
OpenGL renderer: Apple M3 Pro
OpenGL vendor: Apple

Python: 3.11.4
Locale: en_US.UTF-8
Qt version: PyQt6 6.7.1, Qt 6.7.1
Qt runtime version: 6.7.3
Qt platform: cocoa
Hardware:

    Hardware Overview:

      Model Name: MacBook Pro
      Model Identifier: Mac15,6
      Model Number: Z1AX002ENFN/A
      Chip: Apple M3 Pro
      Total Number of Cores: 12 (6 performance and 6 efficiency)
      Memory: 36 GB
      System Firmware Version: 11881.1.1
      OS Loader Version: 11881.1.1

Software:

    System Software Overview:

      System Version: macOS 15.0.1 (24A348)
      Kernel Version: Darwin 24.0.0
      Time since boot: 68 days, 1 hour, 48 minutes

Graphics/Displays:

    Apple M3 Pro:

      Chipset Model: Apple M3 Pro
      Type: GPU
      Bus: Built-In
      Total Number of Cores: 18
      Vendor: Apple (0x106b)
      Metal Support: Metal 3
      Displays:
        DELL U3223QE:
          Resolution: 6720 x 3780
          UI Looks like: 3360 x 1890 @ 60.00Hz
          Main Display: Yes
          Mirror: Off
          Online: Yes
          Rotation: Supported
        Color LCD:
          Display Type: Built-in Liquid Retina XDR Display
          Resolution: 3024 x 1964 Retina
          Mirror: Off
          Online: Yes
          Automatically Adjust Brightness: No
          Connection Type: Internal
        ASUS VG278HE:
          Resolution: 1920 x 1080 (1080p FHD - Full High Definition)
          UI Looks like: 1920 x 1080 @ 60.00Hz
          Mirror: Off
          Online: Yes
          Rotation: Supported


Installed Packages:
    alabaster: 1.0.0
    anyio: 4.7.0
    appdirs: 1.4.4
    appnope: 0.1.4
    asttokens: 3.0.0
    auditwheel: 6.1.0
    autocommand: 2.2.2
    babel: 2.16.0
    backports.tarfile: 1.2.0
    beautifulsoup4: 4.12.3
    biopython: 1.84
    blockdiag: 3.0.0
    blosc2: 3.0.0
    build: 1.2.1
    certifi: 2023.11.17
    cftime: 1.6.4.post1
    charset-normalizer: 3.4.0
    ChimeraX-AddCharge: 1.5.18
    ChimeraX-AddH: 2.2.6
    ChimeraX-AlignmentAlgorithms: 2.0.2
    ChimeraX-AlignmentHdrs: 3.5
    ChimeraX-AlignmentMatrices: 2.1
    ChimeraX-Alignments: 2.16.1
    ChimeraX-AlphaFold: 1.0.1
    ChimeraX-AltlocExplorer: 1.1.2
    ChimeraX-AmberInfo: 1.0
    ChimeraX-Arrays: 1.1
    ChimeraX-Atomic: 1.58.8
    ChimeraX-AtomicLibrary: 14.1.11
    ChimeraX-AtomSearch: 2.0.1
    ChimeraX-AxesPlanes: 2.4
    ChimeraX-BasicActions: 1.1.2
    ChimeraX-BILD: 1.0
    ChimeraX-BlastProtein: 3.0.0
    ChimeraX-BondRot: 2.0.4
    ChimeraX-BugReporter: 1.0.1
    ChimeraX-BuildStructure: 2.13.1
    ChimeraX-Bumps: 1.0
    ChimeraX-BundleBuilder: 1.4.0
    ChimeraX-ButtonPanel: 1.0.1
    ChimeraX-CageBuilder: 1.0.1
    ChimeraX-CellPack: 1.0
    ChimeraX-Centroids: 1.4
    ChimeraX-ChangeChains: 1.1
    ChimeraX-CheckWaters: 1.4
    ChimeraX-ChemGroup: 2.0.1
    ChimeraX-Clashes: 2.3
    ChimeraX-Clipper: 0.23.0
    ChimeraX-ColorActions: 1.0.5
    ChimeraX-ColorGlobe: 1.0
    ChimeraX-ColorKey: 1.5.6
    ChimeraX-CommandLine: 1.2.5
    ChimeraX-ConnectStructure: 2.0.1
    ChimeraX-Contacts: 1.0.1
    ChimeraX-Core: 1.9
    ChimeraX-CoreFormats: 1.2
    ChimeraX-coulombic: 1.4.4
    ChimeraX-Crosslinks: 1.0
    ChimeraX-Crystal: 1.0
    ChimeraX-CrystalContacts: 1.0.1
    ChimeraX-DataFormats: 1.2.3
    ChimeraX-Dicom: 1.2.6
    ChimeraX-DistMonitor: 1.4.2
    ChimeraX-DockPrep: 1.1.3
    ChimeraX-Dssp: 2.0
    ChimeraX-EMDB-SFF: 1.0
    ChimeraX-ESMFold: 1.0
    ChimeraX-FileHistory: 1.0.1
    ChimeraX-FunctionKey: 1.0.1
    ChimeraX-Geometry: 1.3
    ChimeraX-gltf: 1.0
    ChimeraX-Graphics: 1.4.1
    ChimeraX-Hbonds: 2.5
    ChimeraX-Help: 1.3
    ChimeraX-HKCage: 1.3
    ChimeraX-IHM: 1.1
    ChimeraX-ImageFormats: 1.2
    ChimeraX-IMOD: 1.0
    ChimeraX-IO: 1.0.3
    ChimeraX-ISOLDE: 1.8.dev0
    ChimeraX-ItemsInspection: 1.0.1
    ChimeraX-IUPAC: 1.0
    ChimeraX-KVFinder: 1.2.1
    ChimeraX-Label: 1.1.14
    ChimeraX-ListInfo: 1.2.2
    ChimeraX-Log: 1.2
    ChimeraX-LookingGlass: 1.1
    ChimeraX-Maestro: 1.9.1
    ChimeraX-Map: 1.3
    ChimeraX-MapData: 2.0
    ChimeraX-MapEraser: 1.0.1
    ChimeraX-MapFilter: 2.0.1
    ChimeraX-MapFit: 2.0
    ChimeraX-MapSeries: 2.1.1
    ChimeraX-Markers: 1.0.1
    ChimeraX-Mask: 1.0.2
    ChimeraX-maskChains: 1.4
    ChimeraX-MatchMaker: 2.1.6
    ChimeraX-MCopy: 1.0
    ChimeraX-MDcrds: 2.7.2
    ChimeraX-MedicalToolbar: 1.1
    ChimeraX-Meeting: 1.0.1
    ChimeraX-MLP: 1.1.1
    ChimeraX-mmCIF: 2.14.2
    ChimeraX-MMTF: 2.2
    ChimeraX-ModelArchive: 1.0
    ChimeraX-Modeller: 1.5.18
    ChimeraX-ModelPanel: 1.5
    ChimeraX-ModelSeries: 1.0.1
    ChimeraX-Mol2: 2.0.3
    ChimeraX-Mole: 1.0
    ChimeraX-Morph: 1.0.2
    ChimeraX-MouseModes: 1.2
    ChimeraX-Movie: 1.0
    ChimeraX-MutationScores: 1.0
    ChimeraX-Neuron: 1.0
    ChimeraX-Nifti: 1.2
    ChimeraX-NMRSTAR: 1.0.2
    ChimeraX-NRRD: 1.2
    ChimeraX-Nucleotides: 2.0.3
    ChimeraX-OpenCommand: 1.14
    ChimeraX-OrthoPick: 1.0.1
    ChimeraX-PDB: 2.7.6
    ChimeraX-PDBBio: 1.0.1
    ChimeraX-PDBLibrary: 1.0.4
    ChimeraX-PDBMatrices: 1.0
    ChimeraX-PickBlobs: 1.0.1
    ChimeraX-Positions: 1.0
    ChimeraX-PresetMgr: 1.1.2
    ChimeraX-PubChem: 2.2
    ChimeraX-ReadPbonds: 1.0.1
    ChimeraX-Registration: 1.1.2
    ChimeraX-RemoteControl: 1.0
    ChimeraX-RenderByAttr: 1.6.2
    ChimeraX-RenumberResidues: 1.1
    ChimeraX-ResidueFit: 1.0.1
    ChimeraX-RestServer: 1.3.1
    ChimeraX-RNALayout: 1.0
    ChimeraX-RotamerLibMgr: 4.0
    ChimeraX-RotamerLibsDunbrack: 2.0
    ChimeraX-RotamerLibsDynameomics: 2.0
    ChimeraX-RotamerLibsRichardson: 2.0
    ChimeraX-SaveCommand: 1.5.1
    ChimeraX-SchemeMgr: 1.0
    ChimeraX-SDF: 2.0.2
    ChimeraX-Segger: 1.0
    ChimeraX-Segment: 1.0.1
    ChimeraX-Segmentations: 3.5.6
    ChimeraX-SelInspector: 1.0
    ChimeraX-SeqView: 2.14
    ChimeraX-Shape: 1.0.1
    ChimeraX-Shell: 1.0.1
    ChimeraX-Shortcuts: 1.2.0
    ChimeraX-ShowSequences: 1.0.3
    ChimeraX-SideView: 1.0.1
    ChimeraX-SimilarStructures: 1.0.1
    ChimeraX-Smiles: 2.1.2
    ChimeraX-SmoothLines: 1.0
    ChimeraX-SpaceNavigator: 1.0
    ChimeraX-StdCommands: 1.18.1
    ChimeraX-STL: 1.0.1
    ChimeraX-Storm: 1.0
    ChimeraX-StructMeasure: 1.2.1
    ChimeraX-Struts: 1.0.1
    ChimeraX-Surface: 1.0.1
    ChimeraX-SwapAA: 2.0.1
    ChimeraX-SwapRes: 2.5
    ChimeraX-TapeMeasure: 1.0
    ChimeraX-TaskManager: 1.0
    ChimeraX-Test: 1.0
    ChimeraX-Toolbar: 1.2.3
    ChimeraX-ToolshedUtils: 1.2.4
    ChimeraX-Topography: 1.0
    ChimeraX-ToQuest: 1.0
    ChimeraX-Tug: 1.0.1
    ChimeraX-UI: 1.41
    ChimeraX-Umap: 1.0
    ChimeraX-uniprot: 2.3.1
    ChimeraX-UnitCell: 1.0.1
    ChimeraX-ViewDockX: 1.4.4
    ChimeraX-VIPERdb: 1.0
    ChimeraX-Vive: 1.1
    ChimeraX-VolumeMenu: 1.0.1
    ChimeraX-vrml: 1.0
    ChimeraX-VTK: 1.0
    ChimeraX-WavefrontOBJ: 1.0
    ChimeraX-WebCam: 1.0.2
    ChimeraX-WebServices: 1.1.4
    ChimeraX-Zone: 1.0.1
    colorama: 0.4.6
    comm: 0.2.2
    contourpy: 1.3.1
    cxservices: 1.2.3
    cycler: 0.12.1
    Cython: 3.0.10
    debugpy: 1.8.9
    decorator: 5.1.1
    docutils: 0.21.2
    executing: 2.1.0
    filelock: 3.15.4
    fonttools: 4.55.3
    funcparserlib: 2.0.0a0
    glfw: 2.8.0
    grako: 3.16.5
    h11: 0.14.0
    h5py: 3.12.1
    html2text: 2024.2.26
    httpcore: 1.0.7
    httpx: 0.28.1
    idna: 3.10
    ihm: 1.3
    imagecodecs: 2024.6.1
    imagesize: 1.4.1
    importlib_metadata: 8.0.0
    importlib_resources: 6.4.0
    inflect: 7.3.1
    ipykernel: 6.29.5
    ipython: 8.26.0
    ipywidgets: 8.1.5
    jaraco.context: 5.3.0
    jaraco.functools: 4.0.1
    jaraco.text: 3.12.1
    jedi: 0.19.1
    Jinja2: 3.1.4
    jupyter_client: 8.6.2
    jupyter_core: 5.7.2
    jupyterlab_widgets: 3.0.13
    kiwisolver: 1.4.7
    line_profiler: 4.1.3
    lxml: 5.2.2
    lz4: 4.3.3
    MarkupSafe: 3.0.2
    matplotlib: 3.9.2
    matplotlib-inline: 0.1.7
    more-itertools: 10.3.0
    msgpack: 1.0.8
    ndindex: 1.9.2
    nest-asyncio: 1.6.0
    netCDF4: 1.6.5
    networkx: 3.3
    nibabel: 5.2.0
    nptyping: 2.5.0
    numexpr: 2.10.2
    numpy: 1.26.4
    openvr: 1.26.701
    ordered-set: 4.1.0
    packaging: 23.2
    packaging: 24.1
    ParmEd: 4.2.2
    parso: 0.8.4
    pep517: 0.13.1
    pexpect: 4.9.0
    pillow: 10.4.0
    pip: 24.2
    pkginfo: 1.11.1
    platformdirs: 4.3.6
    platformdirs: 4.2.2
    prompt_toolkit: 3.0.48
    psutil: 6.0.0
    ptyprocess: 0.7.0
    pure_eval: 0.2.3
    py-cpuinfo: 9.0.0
    pycollada: 0.8
    pydicom: 2.4.4
    pyelftools: 0.31
    Pygments: 2.18.0
    pynmrstar: 3.3.4
    pynrrd: 1.0.0
    PyOpenGL: 3.1.7
    PyOpenGL-accelerate: 3.1.7
    pyopenxr: 1.0.3401
    pyparsing: 3.2.0
    pyproject_hooks: 1.2.0
    PyQt6-commercial: 6.7.1
    PyQt6-Qt6: 6.7.3
    PyQt6-WebEngine-commercial: 6.7.0
    PyQt6-WebEngine-Qt6: 6.7.3
    PyQt6-WebEngineSubwheel-Qt6: 6.7.3
    PyQt6_sip: 13.8.0
    python-dateutil: 2.9.0.post0
    pytz: 2024.2
    pyzmq: 26.2.0
    qtconsole: 5.5.2
    QtPy: 2.4.2
    qtshim: 1.0
    RandomWords: 0.4.0
    requests: 2.32.3
    scipy: 1.14.0
    setuptools: 72.1.0
    sfftk-rw: 0.8.1
    six: 1.16.0
    sniffio: 1.3.1
    snowballstemmer: 2.2.0
    sortedcontainers: 2.4.0
    soupsieve: 2.6
    Sphinx: 8.0.2
    sphinx-autodoc-typehints: 2.2.3
    sphinxcontrib-applehelp: 2.0.0
    sphinxcontrib-blockdiag: 3.0.0
    sphinxcontrib-devhelp: 2.0.0
    sphinxcontrib-htmlhelp: 2.1.0
    sphinxcontrib-jsmath: 1.0.1
    sphinxcontrib-qthelp: 2.0.0
    sphinxcontrib-serializinghtml: 2.0.0
    stack-data: 0.6.3
    superqt: 0.6.3
    tables: 3.10.1
    tcia_utils: 1.5.1
    tifffile: 2024.7.24
    tinyarray: 1.2.4
    tomli: 2.0.1
    tornado: 6.4.2
    traitlets: 5.14.3
    typeguard: 4.3.0
    typing_extensions: 4.12.2
    typing_extensions: 4.12.2
    tzdata: 2024.2
    urllib3: 2.2.3
    wcwidth: 0.2.13
    webcolors: 24.6.0
    wheel: 0.43.0
    wheel: 0.43.0
    wheel-filename: 1.4.1
    widgetsnbextension: 4.0.13
    zipp: 3.19.2

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