| 1 | {{{
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| 2 | The following bug report has been submitted:
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| 3 | Platform: Linux-5.10.0-1034-oem-x86_64-with-glibc2.14
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| 4 | ChimeraX Version: 1.2.5 (2021-05-24 04:13:57 UTC)
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| 5 | Description
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| 6 | (Describe the actions that caused this problem to occur here)
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| 7 |
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| 8 | Log:
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| 9 | UCSF ChimeraX version: 1.2.5 (2021-05-24)
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| 10 | © 2016-2021 Regents of the University of California. All rights reserved.
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| 11 | How to cite UCSF ChimeraX
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| 12 |
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| 13 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/ucsf-commands.cxc
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| 14 |
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| 15 | > set bgColor white
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| 16 |
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| 17 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/3EI4.pdbqt
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| 18 |
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| 19 | Chain information for 3EI4.pdbqt #1
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| 20 | ---
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| 21 | Chain | Description
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| 22 | A C E | No description available
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| 23 | B D F | No description available
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| 24 |
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| 25 | Opened 3EI4.pdbqt containing 1 structures (70284 atoms, 71031 bonds)
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| 26 |
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| 27 | > wait 5
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| 28 |
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| 29 | > hide surfaces
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| 30 |
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| 31 | > hide atoms
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| 32 |
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| 33 | > show cartoons
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| 34 |
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| 35 | > wait 5
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| 36 |
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| 37 | > addh
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| 38 |
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| 39 | Summary of feedback from adding hydrogens to 3EI4.pdbqt #1
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| 40 | ---
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| 41 | warnings | Not adding hydrogens to /A GLU 368 CB because it is missing heavy-
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| 42 | atom bond partners
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| 43 | Not adding hydrogens to /A ARG 369 CB because it is missing heavy-atom bond
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| 44 | partners
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| 45 | Not adding hydrogens to /A GLN 759 CB because it is missing heavy-atom bond
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| 46 | partners
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| 47 | Not adding hydrogens to /A GLU 779 CB because it is missing heavy-atom bond
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| 48 | partners
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| 49 | Not adding hydrogens to /A THR 780 CB because it is missing heavy-atom bond
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| 50 | partners
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| 51 | 49 messages similar to the above omitted
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| 52 | notes | No usable SEQRES records for 3EI4.pdbqt (#1) chain A; guessing termini
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| 53 | instead
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| 54 | No usable SEQRES records for 3EI4.pdbqt (#1) chain B; guessing termini instead
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| 55 | No usable SEQRES records for 3EI4.pdbqt (#1) chain C; guessing termini instead
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| 56 | No usable SEQRES records for 3EI4.pdbqt (#1) chain D; guessing termini instead
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| 57 | No usable SEQRES records for 3EI4.pdbqt (#1) chain E; guessing termini instead
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| 58 | 1 messages similar to the above omitted
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| 59 | Chain-initial residues that are actual N termini: /A MET 1, /B TRP 54, /C MET
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| 60 | 1, /D TRP 54, /E MET 1, /F TRP 54
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| 61 | Chain-initial residues that are not actual N termini:
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| 62 | Chain-final residues that are actual C termini: /A HIS 1140, /B GLU 421, /C
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| 63 | HIS 1140, /D GLU 421, /E HIS 1140, /F GLU 421
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| 64 | Chain-final residues that are not actual C termini:
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| 65 | 2812 hydrogen bonds
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| 66 | 114 hydrogens added
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| 67 |
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| 68 |
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| 69 | > wait 5
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| 70 |
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| 71 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/3EI4--
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| 72 | > WRM-16.result.pdbqt
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| 73 |
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| 74 | Summary of feedback from opening
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| 75 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/3EI4--WRM-16.result.pdbqt
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| 76 | ---
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| 77 | warnings | Ignored bad PDB record found on line 2
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| 78 | REMARK VINA RESULT: -8.8 0.000 0.000
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| 79 |
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| 80 | Ignored bad PDB record found on line 3
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| 81 | REMARK 5 active torsions:
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| 82 |
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| 83 | Ignored bad PDB record found on line 4
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| 84 | REMARK status: ('A' for Active; 'I' for Inactive)
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| 85 |
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| 86 | Ignored bad PDB record found on line 5
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| 87 | REMARK 1 A between atoms: C_9 and O_15
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| 88 |
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| 89 | Ignored bad PDB record found on line 6
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| 90 | REMARK 2 A between atoms: C_10 and O_17
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| 91 |
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| 92 | 184 messages similar to the above omitted
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| 93 |
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| 94 | Opened 3EI4--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
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| 95 | bonds)
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| 96 |
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| 97 | > wait 5
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| 98 |
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| 99 | > close #2.2-9
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| 100 |
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| 101 | > wait 5
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| 102 |
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| 103 | > contacts :UNL radius 0.05 log true saveFile
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| 104 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3EI4--
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| 105 | > WRM-16.contacts.txt
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| 106 |
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| 107 |
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| 108 | Allowed overlap: -0.4
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| 109 | H-bond overlap reduction: 0.4
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| 110 | Ignore contacts between atoms separated by 4 bonds or less
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| 111 | Detect intra-residue contacts: False
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| 112 | Detect intra-molecule contacts: True
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| 113 |
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| 114 | 40 contacts
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| 115 | atom1 atom2 overlap distance
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| 116 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3EI4.pdbqt #1/C ARG 639 HE 0.326 2.554
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| 117 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C PHE 458 O 0.049 3.311
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| 118 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3EI4.pdbqt #1/C ARG 639 NE -0.005 3.510
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| 119 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3EI4.pdbqt #1/C LEU 410 HN -0.006 2.886
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| 120 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C PHE 459 HB2 -0.009 2.889
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| 121 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C LEU 638 O -0.028 3.388
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| 122 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 O 3EI4.pdbqt #1/C ILE 591 HN -0.045 2.065
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| 123 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C ALA 501 O -0.050 3.410
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| 124 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3EI4.pdbqt #1/C LEU 410 O -0.056 3.416
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| 125 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C ARG 639 HG2 -0.071 2.831
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| 126 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C VAL 637 CG1 -0.071 3.531
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| 127 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 O 3EI4.pdbqt #1/C VAL 637 2HG1 -0.089 2.509
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| 128 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C ALA 501 C -0.092 3.672
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| 129 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C LEU 592 HB2 -0.115 2.995
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| 130 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C LEU 592 CB -0.121 3.701
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| 131 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C PHE 459 HD2 -0.131 2.891
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| 132 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 O 3EI4.pdbqt #1/C SER 590 HA -0.193 2.613
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| 133 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C ALA 501 HB2 -0.227 3.107
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| 134 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C TYR 678 HD2 -0.237 2.997
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| 135 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C ARG 639 CG -0.240 3.700
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| 136 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C TYR 678 CD2 -0.246 3.706
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| 137 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C ILE 591 O -0.258 3.618
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| 138 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C ARG 639 HE -0.271 3.031
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| 139 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 O 3EI4.pdbqt #1/C ILE 591 O -0.284 3.184
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| 140 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 O 3EI4.pdbqt #1/C ILE 591 O -0.286 3.226
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| 141 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C PHE 459 CD2 -0.291 3.751
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| 142 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C PHE 459 CD2 -0.291 3.751
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| 143 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C LEU 638 HB2 -0.296 3.176
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| 144 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C PHE 459 HD2 -0.312 3.072
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| 145 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3EI4.pdbqt #1/C MET 679 O -0.331 3.691
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| 146 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3EI4.pdbqt #1/C ARG 639 2HH2 -0.331 3.211
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| 147 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 O 3EI4.pdbqt #1/C SER 590 CA -0.344 3.464
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| 148 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C VAL 637 2HG1 -0.350 3.110
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| 149 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C LEU 638 C -0.357 3.937
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| 150 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C ALA 501 CB -0.367 3.947
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| 151 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 O 3EI4.pdbqt #1/C ILE 591 N -0.374 3.019
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| 152 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C VAL 637 CG1 -0.386 3.696
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| 153 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3EI4.pdbqt #1/C LEU 410 N -0.387 3.892
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| 154 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C PHE 459 CB -0.394 3.974
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| 155 | 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 C 3EI4.pdbqt #1/C LEU 592 HB1 -0.394 3.274
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| 156 |
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| 157 |
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| 158 |
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| 159 | 40 contacts
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| 160 |
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| 161 | > hbonds :UNL showDist true radius 0.05 log true saveFile
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| 162 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3EI4--
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| 163 | > WRM-16.hbonds.txt
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| 164 |
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| 165 |
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| 166 | Finding intermodel H-bonds
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| 167 | Finding intramodel H-bonds
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| 168 | Constraints relaxed by 0.4 angstroms and 20 degrees
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| 169 | Models used:
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| 170 | 1 3EI4.pdbqt
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| 171 | 2.1 3EI4--WRM-16.result.pdbqt
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| 172 |
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| 173 | 1 H-bonds
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| 174 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
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| 175 | 3EI4.pdbqt #1/C ILE 591 N 3EI4--WRM-16.result.pdbqt #2.1/? UNL 1 O 3EI4.pdbqt #1/C ILE 591 HN 3.019 2.065
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| 176 |
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| 177 |
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| 178 |
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| 179 | 1 hydrogen bonds found
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| 180 |
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| 181 | > select :UNL
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| 182 |
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| 183 | 28 atoms, 31 bonds, 1 residue, 1 model selected
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| 184 |
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| 185 | > label sel text "Ligand "
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| 186 |
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| 187 | > label height 1
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| 188 |
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| 189 | > ~select
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| 190 |
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| 191 | Nothing selected
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| 192 |
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| 193 | > 2dlabels text "Binding Energy: -8.8 kcal/mol" color red size 18 xpos .03
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| 194 | > ypos .95
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| 195 |
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| 196 | > 2dlabels text "3EI4 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
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| 197 |
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| 198 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3EI4--
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| 199 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
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| 200 | > true
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| 201 |
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| 202 | > select :UNL
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| 203 |
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| 204 | 28 atoms, 31 bonds, 1 residue, 1 model selected
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| 205 |
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| 206 | > view sel
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| 207 |
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| 208 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3EI4--
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| 209 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
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| 210 | > true
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| 211 |
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| 212 | > close
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| 213 |
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| 214 | > wait 5
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| 215 |
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| 216 | > set bgColor white
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| 217 |
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| 218 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/2PA2.pdbqt
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| 219 |
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| 220 | Chain information for 2PA2.pdbqt #1
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| 221 | ---
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| 222 | Chain | Description
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| 223 | A B | No description available
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| 224 |
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| 225 | Opened 2PA2.pdbqt containing 1 structures (3578 atoms, 3614 bonds)
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| 226 |
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| 227 | > wait 5
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| 228 |
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| 229 | > hide surfaces
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| 230 |
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| 231 | > hide atoms
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| 232 |
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| 233 | > show cartoons
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| 234 |
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| 235 | > wait 5
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| 236 |
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| 237 | > addh
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| 238 |
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| 239 | Summary of feedback from adding hydrogens to 2PA2.pdbqt #1
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| 240 | ---
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| 241 | notes | No usable SEQRES records for 2PA2.pdbqt (#1) chain A; guessing termini
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| 242 | instead
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| 243 | No usable SEQRES records for 2PA2.pdbqt (#1) chain B; guessing termini instead
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| 244 | Chain-initial residues that are actual N termini: /A LYS 40, /B LYS 40
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| 245 | Chain-initial residues that are not actual N termini: /A GLY 124, /B GLY 124
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| 246 | Chain-final residues that are actual C termini: /A PHE 176, /B PHE 176
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| 247 | Chain-final residues that are not actual C termini: /A PHE 94, /B PHE 94
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| 248 | 173 hydrogen bonds
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| 249 | Adding 'H' to /A GLY 124
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| 250 | Adding 'H' to /B GLY 124
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| 251 | /A PHE 94 is not terminus, removing H atom from 'C'
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| 252 | /B PHE 94 is not terminus, removing H atom from 'C'
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| 253 | 0 hydrogens added
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| 254 |
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| 255 |
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| 256 | > wait 5
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| 257 |
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| 258 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2PA2--
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| 259 | > WRM-16.result.pdbqt
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| 260 |
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| 261 | Summary of feedback from opening
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| 262 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2PA2--WRM-16.result.pdbqt
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| 263 | ---
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| 264 | warnings | Ignored bad PDB record found on line 2
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| 265 | REMARK VINA RESULT: -8.4 0.000 0.000
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| 266 |
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| 267 | Ignored bad PDB record found on line 3
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| 268 | REMARK 5 active torsions:
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| 269 |
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| 270 | Ignored bad PDB record found on line 4
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| 271 | REMARK status: ('A' for Active; 'I' for Inactive)
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| 272 |
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| 273 | Ignored bad PDB record found on line 5
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| 274 | REMARK 1 A between atoms: C_9 and O_15
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| 275 |
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| 276 | Ignored bad PDB record found on line 6
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| 277 | REMARK 2 A between atoms: C_10 and O_17
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| 278 |
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| 279 | 184 messages similar to the above omitted
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| 280 |
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| 281 | Opened 2PA2--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
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| 282 | bonds)
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| 283 |
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| 284 | > wait 5
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| 285 |
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| 286 | > close #2.2-9
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| 287 |
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| 288 | > wait 5
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| 289 |
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| 290 | > contacts :UNL radius 0.05 log true saveFile
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| 291 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2PA2--
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| 292 | > WRM-16.contacts.txt
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| 293 |
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| 294 |
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| 295 | Allowed overlap: -0.4
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| 296 | H-bond overlap reduction: 0.4
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| 297 | Ignore contacts between atoms separated by 4 bonds or less
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| 298 | Detect intra-residue contacts: False
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| 299 | Detect intra-molecule contacts: True
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| 300 |
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| 301 | 42 contacts
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| 302 | atom1 atom2 overlap distance
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| 303 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A ARG 139 1HH1 0.226 2.384
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| 304 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2PA2.pdbqt #1/A ARG 139 1HH1 0.203 1.817
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| 305 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/B HIS 130 HE2 0.129 2.481
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| 306 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/B ARG 128 HB2 0.110 2.650
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| 307 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/B HIS 130 HE1 0.107 2.773
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| 308 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A TRP 171 HB2 0.007 2.753
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| 309 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/B HIS 130 HE2 0.001 2.759
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| 310 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A TRP 171 HB2 -0.038 2.648
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| 311 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/B HIS 130 HE2 -0.039 2.649
|
|---|
| 312 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A ARG 139 1HH2 -0.042 2.922
|
|---|
| 313 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2PA2.pdbqt #1/A ARG 139 1HH2 -0.049 2.109
|
|---|
| 314 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2PA2.pdbqt #1/B HIS 92 O -0.078 3.438
|
|---|
| 315 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/B HIS 130 CE1 -0.094 3.674
|
|---|
| 316 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A ARG 139 1HH2 -0.105 2.985
|
|---|
| 317 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A VAL 43 CG1 -0.107 3.687
|
|---|
| 318 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2PA2.pdbqt #1/A PRO 47 HA -0.111 2.531
|
|---|
| 319 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A TRP 171 HD1 -0.114 2.874
|
|---|
| 320 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A TRP 171 HD1 -0.119 2.879
|
|---|
| 321 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2PA2.pdbqt #1/B ARG 128 O -0.121 3.481
|
|---|
| 322 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2PA2.pdbqt #1/B HIS 130 HE1 -0.121 2.581
|
|---|
| 323 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2PA2.pdbqt #1/A ARG 139 NH1 -0.139 2.784
|
|---|
| 324 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A ARG 139 NH1 -0.150 3.385
|
|---|
| 325 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/B HIS 130 NE2 -0.172 3.557
|
|---|
| 326 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A TRP 171 HB2 -0.175 2.785
|
|---|
| 327 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A TRP 171 CD1 -0.211 3.671
|
|---|
| 328 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A LYS 169 O -0.229 3.319
|
|---|
| 329 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A ARG 139 NH2 -0.235 3.740
|
|---|
| 330 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2PA2.pdbqt #1/A VAL 43 O -0.237 3.137
|
|---|
| 331 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/B HIS 130 NE2 -0.243 3.478
|
|---|
| 332 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/B ARG 128 HD2 -0.251 3.011
|
|---|
| 333 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A TRP 171 CB -0.266 3.576
|
|---|
| 334 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2PA2.pdbqt #1/A TRP 171 HB2 -0.278 2.698
|
|---|
| 335 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A PRO 47 CB -0.283 3.863
|
|---|
| 336 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/B ARG 128 CB -0.291 3.751
|
|---|
| 337 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A VAL 43 1HG1 -0.297 3.177
|
|---|
| 338 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2PA2.pdbqt #1/B HIS 92 HN -0.300 3.180
|
|---|
| 339 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A TRP 171 CD1 -0.306 3.766
|
|---|
| 340 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A TRP 171 CB -0.325 3.785
|
|---|
| 341 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/B HIS 130 NE2 -0.331 3.566
|
|---|
| 342 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A TRP 171 HN -0.354 3.234
|
|---|
| 343 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/A VAL 43 HB -0.364 2.974
|
|---|
| 344 | 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2PA2.pdbqt #1/B HIS 130 HE2 -0.383 3.143
|
|---|
| 345 |
|
|---|
| 346 |
|
|---|
| 347 |
|
|---|
| 348 | 42 contacts
|
|---|
| 349 |
|
|---|
| 350 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 351 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2PA2--
|
|---|
| 352 | > WRM-16.hbonds.txt
|
|---|
| 353 |
|
|---|
| 354 |
|
|---|
| 355 | Finding intermodel H-bonds
|
|---|
| 356 | Finding intramodel H-bonds
|
|---|
| 357 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 358 | Models used:
|
|---|
| 359 | 1 2PA2.pdbqt
|
|---|
| 360 | 2.1 2PA2--WRM-16.result.pdbqt
|
|---|
| 361 |
|
|---|
| 362 | 4 H-bonds
|
|---|
| 363 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 364 | 2PA2.pdbqt #1/A ARG 139 NH1 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2PA2.pdbqt #1/A ARG 139 1HH1 3.380 2.525
|
|---|
| 365 | 2PA2.pdbqt #1/A ARG 139 NH1 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2PA2.pdbqt #1/A ARG 139 1HH1 2.784 1.817
|
|---|
| 366 | 2PA2.pdbqt #1/A ARG 139 NH2 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2PA2.pdbqt #1/A ARG 139 1HH2 3.087 2.109
|
|---|
| 367 | 2PA2.pdbqt #1/A TRP 171 N 2PA2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2PA2.pdbqt #1/A TRP 171 HN 3.576 2.621
|
|---|
| 368 |
|
|---|
| 369 |
|
|---|
| 370 |
|
|---|
| 371 | 4 hydrogen bonds found
|
|---|
| 372 |
|
|---|
| 373 | > select :UNL
|
|---|
| 374 |
|
|---|
| 375 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 376 |
|
|---|
| 377 | > label sel text "Ligand "
|
|---|
| 378 |
|
|---|
| 379 | > label height 1
|
|---|
| 380 |
|
|---|
| 381 | > ~select
|
|---|
| 382 |
|
|---|
| 383 | Nothing selected
|
|---|
| 384 |
|
|---|
| 385 | > 2dlabels text "Binding Energy: -8.4 kcal/mol" color red size 18 xpos .03
|
|---|
| 386 | > ypos .95
|
|---|
| 387 |
|
|---|
| 388 | > 2dlabels text "2PA2 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 389 |
|
|---|
| 390 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2PA2--
|
|---|
| 391 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 392 | > true
|
|---|
| 393 |
|
|---|
| 394 | > select :UNL
|
|---|
| 395 |
|
|---|
| 396 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 397 |
|
|---|
| 398 | > view sel
|
|---|
| 399 |
|
|---|
| 400 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2PA2--
|
|---|
| 401 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 402 | > true
|
|---|
| 403 |
|
|---|
| 404 | > close
|
|---|
| 405 |
|
|---|
| 406 | > wait 5
|
|---|
| 407 |
|
|---|
| 408 | > set bgColor white
|
|---|
| 409 |
|
|---|
| 410 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/2KV2.pdbqt
|
|---|
| 411 |
|
|---|
| 412 | Chain information for 2KV2.pdbqt #1
|
|---|
| 413 | ---
|
|---|
| 414 | Chain | Description
|
|---|
| 415 | A | No description available
|
|---|
| 416 |
|
|---|
| 417 | Opened 2KV2.pdbqt containing 1 structures (1351 atoms, 1361 bonds)
|
|---|
| 418 |
|
|---|
| 419 | > wait 5
|
|---|
| 420 |
|
|---|
| 421 | > hide surfaces
|
|---|
| 422 |
|
|---|
| 423 | > hide atoms
|
|---|
| 424 |
|
|---|
| 425 | > show cartoons
|
|---|
| 426 |
|
|---|
| 427 | > wait 5
|
|---|
| 428 |
|
|---|
| 429 | > addh
|
|---|
| 430 |
|
|---|
| 431 | Summary of feedback from adding hydrogens to 2KV2.pdbqt #1
|
|---|
| 432 | ---
|
|---|
| 433 | notes | No usable SEQRES records for 2KV2.pdbqt (#1) chain A; guessing termini
|
|---|
| 434 | instead
|
|---|
| 435 | Chain-initial residues that are actual N termini: /A GLN 1
|
|---|
| 436 | Chain-initial residues that are not actual N termini:
|
|---|
| 437 | Chain-final residues that are actual C termini: /A ASP 85
|
|---|
| 438 | Chain-final residues that are not actual C termini:
|
|---|
| 439 | 61 hydrogen bonds
|
|---|
| 440 | 1 hydrogens added
|
|---|
| 441 |
|
|---|
| 442 |
|
|---|
| 443 | > wait 5
|
|---|
| 444 |
|
|---|
| 445 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2KV2--
|
|---|
| 446 | > WRM-16.result.pdbqt
|
|---|
| 447 |
|
|---|
| 448 | Summary of feedback from opening
|
|---|
| 449 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2KV2--WRM-16.result.pdbqt
|
|---|
| 450 | ---
|
|---|
| 451 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 452 | REMARK VINA RESULT: -6.4 0.000 0.000
|
|---|
| 453 |
|
|---|
| 454 | Ignored bad PDB record found on line 3
|
|---|
| 455 | REMARK 5 active torsions:
|
|---|
| 456 |
|
|---|
| 457 | Ignored bad PDB record found on line 4
|
|---|
| 458 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 459 |
|
|---|
| 460 | Ignored bad PDB record found on line 5
|
|---|
| 461 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 462 |
|
|---|
| 463 | Ignored bad PDB record found on line 6
|
|---|
| 464 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 465 |
|
|---|
| 466 | 184 messages similar to the above omitted
|
|---|
| 467 |
|
|---|
| 468 | Opened 2KV2--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 469 | bonds)
|
|---|
| 470 |
|
|---|
| 471 | > wait 5
|
|---|
| 472 |
|
|---|
| 473 | > close #2.2-9
|
|---|
| 474 |
|
|---|
| 475 | > wait 5
|
|---|
| 476 |
|
|---|
| 477 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 478 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2KV2--
|
|---|
| 479 | > WRM-16.contacts.txt
|
|---|
| 480 |
|
|---|
| 481 |
|
|---|
| 482 | Allowed overlap: -0.4
|
|---|
| 483 | H-bond overlap reduction: 0.4
|
|---|
| 484 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 485 | Detect intra-residue contacts: False
|
|---|
| 486 | Detect intra-molecule contacts: True
|
|---|
| 487 |
|
|---|
| 488 | 52 contacts
|
|---|
| 489 | atom1 atom2 overlap distance
|
|---|
| 490 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TYR 76 HB2 0.640 2.240
|
|---|
| 491 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A LYS 75 HB3 0.469 2.291
|
|---|
| 492 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TYR 76 CB 0.306 3.274
|
|---|
| 493 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TYR 76 HD2 0.278 2.482
|
|---|
| 494 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2KV2.pdbqt #1/A THR 80 HB 0.207 2.673
|
|---|
| 495 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KV2.pdbqt #1/A LYS 8 CE 0.105 3.055
|
|---|
| 496 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A LYS 75 HD2 0.105 2.655
|
|---|
| 497 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A LYS 75 CB 0.100 3.360
|
|---|
| 498 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TRP 79 HB2 0.075 2.685
|
|---|
| 499 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2KV2.pdbqt #1/A THR 80 CB 0.039 3.541
|
|---|
| 500 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TYR 76 CD2 -0.031 3.491
|
|---|
| 501 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TRP 79 HE3 -0.057 2.817
|
|---|
| 502 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TRP 79 HD1 -0.060 2.820
|
|---|
| 503 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TRP 79 CE3 -0.080 3.540
|
|---|
| 504 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TRP 79 CD1 -0.084 3.544
|
|---|
| 505 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A LYS 75 HZ3 -0.099 2.979
|
|---|
| 506 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TRP 79 CD1 -0.106 3.686
|
|---|
| 507 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A THR 80 HB -0.115 2.875
|
|---|
| 508 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TYR 76 HB2 -0.131 3.011
|
|---|
| 509 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KV2.pdbqt #1/A LYS 8 HE2 -0.136 2.596
|
|---|
| 510 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TYR 76 HA -0.165 2.775
|
|---|
| 511 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TYR 76 HA -0.207 2.817
|
|---|
| 512 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A LYS 75 CD -0.208 3.668
|
|---|
| 513 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2KV2.pdbqt #1/A THR 80 OG1 -0.214 3.594
|
|---|
| 514 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TRP 79 CB -0.214 3.674
|
|---|
| 515 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A LYS 75 HB3 -0.227 2.837
|
|---|
| 516 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TRP 79 CE3 -0.237 3.547
|
|---|
| 517 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TYR 76 HD2 -0.262 3.142
|
|---|
| 518 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A LYS 75 C -0.263 3.723
|
|---|
| 519 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2KV2.pdbqt #1/A TRP 79 CE3 -0.272 3.852
|
|---|
| 520 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2KV2.pdbqt #1/A TRP 79 CZ3 -0.273 3.853
|
|---|
| 521 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2KV2.pdbqt #1/A TRP 79 HZ3 -0.277 3.157
|
|---|
| 522 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2KV2.pdbqt #1/A TRP 79 HE3 -0.280 3.160
|
|---|
| 523 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TYR 76 CB -0.297 3.607
|
|---|
| 524 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TYR 76 CD2 -0.310 3.890
|
|---|
| 525 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TYR 76 CB -0.317 3.897
|
|---|
| 526 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A LYS 75 O -0.323 3.563
|
|---|
| 527 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KV2.pdbqt #1/A LYS 8 HE2 -0.324 2.744
|
|---|
| 528 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KV2.pdbqt #1/A LYS 75 HB3 -0.325 2.785
|
|---|
| 529 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A LYS 75 O -0.329 3.569
|
|---|
| 530 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KV2.pdbqt #1/A LYS 75 CB -0.330 3.490
|
|---|
| 531 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TYR 76 HB2 -0.331 2.941
|
|---|
| 532 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TYR 76 O -0.336 3.576
|
|---|
| 533 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KV2.pdbqt #1/A TRP 79 CG -0.355 3.515
|
|---|
| 534 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TRP 79 HE3 -0.360 2.970
|
|---|
| 535 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A LYS 75 NZ -0.373 3.878
|
|---|
| 536 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TRP 79 CG -0.376 3.956
|
|---|
| 537 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KV2.pdbqt #1/A VAL 72 3HG2 -0.383 2.803
|
|---|
| 538 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KV2.pdbqt #1/A LYS 8 HE3 -0.388 2.848
|
|---|
| 539 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A TYR 76 HD2 -0.388 3.148
|
|---|
| 540 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A LYS 75 HB3 -0.391 3.151
|
|---|
| 541 | 2KV2--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KV2.pdbqt #1/A LYS 8 HE2 -0.399 3.009
|
|---|
| 542 |
|
|---|
| 543 |
|
|---|
| 544 |
|
|---|
| 545 | 52 contacts
|
|---|
| 546 |
|
|---|
| 547 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 548 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2KV2--
|
|---|
| 549 | > WRM-16.hbonds.txt
|
|---|
| 550 |
|
|---|
| 551 |
|
|---|
| 552 | Finding intermodel H-bonds
|
|---|
| 553 | Finding intramodel H-bonds
|
|---|
| 554 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 555 | Models used:
|
|---|
| 556 | 1 2KV2.pdbqt
|
|---|
| 557 | 2.1 2KV2--WRM-16.result.pdbqt
|
|---|
| 558 |
|
|---|
| 559 | 0 H-bonds
|
|---|
| 560 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 561 |
|
|---|
| 562 |
|
|---|
| 563 |
|
|---|
| 564 | 0 hydrogen bonds found
|
|---|
| 565 |
|
|---|
| 566 | > select :UNL
|
|---|
| 567 |
|
|---|
| 568 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 569 |
|
|---|
| 570 | > label sel text "Ligand "
|
|---|
| 571 |
|
|---|
| 572 | > label height 1
|
|---|
| 573 |
|
|---|
| 574 | > ~select
|
|---|
| 575 |
|
|---|
| 576 | Nothing selected
|
|---|
| 577 |
|
|---|
| 578 | > 2dlabels text "Binding Energy: -6.4 kcal/mol" color red size 18 xpos .03
|
|---|
| 579 | > ypos .95
|
|---|
| 580 |
|
|---|
| 581 | > 2dlabels text "2KV2 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 582 |
|
|---|
| 583 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2KV2--
|
|---|
| 584 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 585 | > true
|
|---|
| 586 |
|
|---|
| 587 | > select :UNL
|
|---|
| 588 |
|
|---|
| 589 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 590 |
|
|---|
| 591 | > view sel
|
|---|
| 592 |
|
|---|
| 593 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2KV2--
|
|---|
| 594 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 595 | > true
|
|---|
| 596 |
|
|---|
| 597 | > close
|
|---|
| 598 |
|
|---|
| 599 | > wait 5
|
|---|
| 600 |
|
|---|
| 601 | > set bgColor white
|
|---|
| 602 |
|
|---|
| 603 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/3CO6.pdbqt
|
|---|
| 604 |
|
|---|
| 605 | Chain information for 3CO6.pdbqt #1
|
|---|
| 606 | ---
|
|---|
| 607 | Chain | Description
|
|---|
| 608 | A | No description available
|
|---|
| 609 | B | No description available
|
|---|
| 610 | C | No description available
|
|---|
| 611 |
|
|---|
| 612 | Opened 3CO6.pdbqt containing 1 structures (2476 atoms, 2572 bonds)
|
|---|
| 613 |
|
|---|
| 614 | > wait 5
|
|---|
| 615 |
|
|---|
| 616 | > hide surfaces
|
|---|
| 617 |
|
|---|
| 618 | > hide atoms
|
|---|
| 619 |
|
|---|
| 620 | > show cartoons
|
|---|
| 621 |
|
|---|
| 622 | > wait 5
|
|---|
| 623 |
|
|---|
| 624 | > addh
|
|---|
| 625 |
|
|---|
| 626 | Summary of feedback from adding hydrogens to 3CO6.pdbqt #1
|
|---|
| 627 | ---
|
|---|
| 628 | warnings | Not adding hydrogens to /C LYS 192 CB because it is missing heavy-
|
|---|
| 629 | atom bond partners
|
|---|
| 630 | Not adding hydrogens to /C LYS 198 CB because it is missing heavy-atom bond
|
|---|
| 631 | partners
|
|---|
| 632 | Not adding hydrogens to /C ASN 204 CB because it is missing heavy-atom bond
|
|---|
| 633 | partners
|
|---|
| 634 | Not adding hydrogens to /C GLU 242 CB because it is missing heavy-atom bond
|
|---|
| 635 | partners
|
|---|
| 636 | notes | No usable SEQRES records for 3CO6.pdbqt (#1) chain A; guessing termini
|
|---|
| 637 | instead
|
|---|
| 638 | No usable SEQRES records for 3CO6.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 639 | No usable SEQRES records for 3CO6.pdbqt (#1) chain C; guessing termini instead
|
|---|
| 640 | Chain-initial residues that are actual N termini: /A DT -4, /B DC 13, /C SER
|
|---|
| 641 | 154
|
|---|
| 642 | Chain-initial residues that are not actual N termini:
|
|---|
| 643 | Chain-final residues that are actual C termini: /A DG 12, /B DA 28, /C GLY 244
|
|---|
| 644 | Chain-final residues that are not actual C termini:
|
|---|
| 645 | 127 hydrogen bonds
|
|---|
| 646 | 4 hydrogens added
|
|---|
| 647 |
|
|---|
| 648 |
|
|---|
| 649 | > wait 5
|
|---|
| 650 |
|
|---|
| 651 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/3CO6--
|
|---|
| 652 | > WRM-16.result.pdbqt
|
|---|
| 653 |
|
|---|
| 654 | Summary of feedback from opening
|
|---|
| 655 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/3CO6--WRM-16.result.pdbqt
|
|---|
| 656 | ---
|
|---|
| 657 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 658 | REMARK VINA RESULT: -9.1 0.000 0.000
|
|---|
| 659 |
|
|---|
| 660 | Ignored bad PDB record found on line 3
|
|---|
| 661 | REMARK 5 active torsions:
|
|---|
| 662 |
|
|---|
| 663 | Ignored bad PDB record found on line 4
|
|---|
| 664 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 665 |
|
|---|
| 666 | Ignored bad PDB record found on line 5
|
|---|
| 667 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 668 |
|
|---|
| 669 | Ignored bad PDB record found on line 6
|
|---|
| 670 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 671 |
|
|---|
| 672 | 184 messages similar to the above omitted
|
|---|
| 673 |
|
|---|
| 674 | Opened 3CO6--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 675 | bonds)
|
|---|
| 676 |
|
|---|
| 677 | > wait 5
|
|---|
| 678 |
|
|---|
| 679 | > close #2.2-9
|
|---|
| 680 |
|
|---|
| 681 | > wait 5
|
|---|
| 682 |
|
|---|
| 683 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 684 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3CO6--
|
|---|
| 685 | > WRM-16.contacts.txt
|
|---|
| 686 |
|
|---|
| 687 |
|
|---|
| 688 | Allowed overlap: -0.4
|
|---|
| 689 | H-bond overlap reduction: 0.4
|
|---|
| 690 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 691 | Detect intra-residue contacts: False
|
|---|
| 692 | Detect intra-molecule contacts: True
|
|---|
| 693 |
|
|---|
| 694 | 57 contacts
|
|---|
| 695 | atom1 atom2 overlap distance
|
|---|
| 696 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3CO6.pdbqt #1/A DT 4 H4' 0.285 2.595
|
|---|
| 697 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/C SER 234 HA 0.279 2.481
|
|---|
| 698 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/C GLN 227 OE1 0.215 3.025
|
|---|
| 699 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/B DA 25 O3' 0.090 3.290
|
|---|
| 700 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/C ARG 225 2HH1 0.039 2.721
|
|---|
| 701 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/C ARG 225 NH1 0.011 3.374
|
|---|
| 702 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/B DA 25 C5' 0.002 3.578
|
|---|
| 703 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/B DA 24 H3 0.000 2.880
|
|---|
| 704 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/A DG 3 O4' -0.016 3.396
|
|---|
| 705 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/B DC 26 H4' -0.026 2.906
|
|---|
| 706 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/B DA 25 1H5' -0.041 2.921
|
|---|
| 707 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 3CO6.pdbqt #1/B DA 24 C2 -0.066 3.226
|
|---|
| 708 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/C SER 234 CA -0.080 3.540
|
|---|
| 709 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/A DG 3 H22 -0.090 2.850
|
|---|
| 710 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 3CO6.pdbqt #1/B DA 24 H3 -0.095 2.155
|
|---|
| 711 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/C LYS 233 O -0.116 3.356
|
|---|
| 712 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3CO6.pdbqt #1/A DT 4 C4' -0.123 3.703
|
|---|
| 713 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/A DG 3 H3 -0.125 2.885
|
|---|
| 714 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/C SER 235 OG -0.180 3.440
|
|---|
| 715 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/A DG 3 H22 -0.187 2.947
|
|---|
| 716 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/A DT 4 H4' -0.190 2.800
|
|---|
| 717 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 3CO6.pdbqt #1/B DA 23 H2 -0.212 2.632
|
|---|
| 718 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/B DA 25 2H5' -0.212 3.092
|
|---|
| 719 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/C SER 235 OG -0.222 3.482
|
|---|
| 720 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 3CO6.pdbqt #1/B DA 24 N3 -0.223 2.908
|
|---|
| 721 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 3CO6.pdbqt #1/B DA 23 C2 -0.223 3.343
|
|---|
| 722 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/B DC 26 C4' -0.229 3.809
|
|---|
| 723 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/A DG 3 C4' -0.230 3.810
|
|---|
| 724 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 3CO6.pdbqt #1/B DA 24 H2 -0.237 2.697
|
|---|
| 725 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/B DC 26 P -0.239 3.990
|
|---|
| 726 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 3CO6.pdbqt #1/A DT 2 O4' -0.260 3.180
|
|---|
| 727 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 3CO6.pdbqt #1/A DT 2 H4' -0.264 2.724
|
|---|
| 728 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/B DA 25 H4' -0.269 2.879
|
|---|
| 729 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/C LYS 233 O -0.273 3.513
|
|---|
| 730 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/B DA 24 N3 -0.286 3.791
|
|---|
| 731 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 3CO6.pdbqt #1/B DA 24 O4' -0.296 3.216
|
|---|
| 732 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 3CO6.pdbqt #1/B DA 24 H2 -0.297 2.717
|
|---|
| 733 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/A DT 4 C4' -0.299 3.759
|
|---|
| 734 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/C GLN 227 CD -0.302 3.762
|
|---|
| 735 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/B DA 25 H4' -0.308 2.918
|
|---|
| 736 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/A DG 3 N3 -0.316 3.701
|
|---|
| 737 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/A DG 3 H4' -0.322 3.202
|
|---|
| 738 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/A DG 3 N2 -0.323 3.708
|
|---|
| 739 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/A DT 4 H4' -0.326 3.086
|
|---|
| 740 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/C ARG 225 NH1 -0.332 3.717
|
|---|
| 741 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 3CO6.pdbqt #1/B DA 24 C4 -0.337 3.457
|
|---|
| 742 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 3CO6.pdbqt #1/A DT 2 O2 -0.341 3.281
|
|---|
| 743 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/C ARG 225 2HH1 -0.352 3.112
|
|---|
| 744 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/A DT 4 O4' -0.360 3.620
|
|---|
| 745 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 3CO6.pdbqt #1/B DA 24 N3 -0.360 3.005
|
|---|
| 746 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/B DC 26 C5' -0.366 3.946
|
|---|
| 747 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/A DT 4 C4' -0.374 3.684
|
|---|
| 748 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/C SER 235 N -0.392 3.777
|
|---|
| 749 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 3CO6.pdbqt #1/B DA 24 C1' -0.394 3.514
|
|---|
| 750 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/C SER 235 N -0.394 3.779
|
|---|
| 751 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/B DC 26 OP1 -0.397 3.777
|
|---|
| 752 | 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 3CO6.pdbqt #1/B DA 25 C4' -0.400 3.980
|
|---|
| 753 |
|
|---|
| 754 |
|
|---|
| 755 |
|
|---|
| 756 | 57 contacts
|
|---|
| 757 |
|
|---|
| 758 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 759 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3CO6--
|
|---|
| 760 | > WRM-16.hbonds.txt
|
|---|
| 761 |
|
|---|
| 762 |
|
|---|
| 763 | Finding intermodel H-bonds
|
|---|
| 764 | Finding intramodel H-bonds
|
|---|
| 765 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 766 | Models used:
|
|---|
| 767 | 1 3CO6.pdbqt
|
|---|
| 768 | 2.1 3CO6--WRM-16.result.pdbqt
|
|---|
| 769 |
|
|---|
| 770 | 1 H-bonds
|
|---|
| 771 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 772 | 3CO6.pdbqt #1/B DA 24 N3 3CO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 3CO6.pdbqt #1/B DA 24 H3 2.908 2.155
|
|---|
| 773 |
|
|---|
| 774 |
|
|---|
| 775 |
|
|---|
| 776 | 1 hydrogen bonds found
|
|---|
| 777 |
|
|---|
| 778 | > select :UNL
|
|---|
| 779 |
|
|---|
| 780 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 781 |
|
|---|
| 782 | > label sel text "Ligand "
|
|---|
| 783 |
|
|---|
| 784 | > label height 1
|
|---|
| 785 |
|
|---|
| 786 | > ~select
|
|---|
| 787 |
|
|---|
| 788 | Nothing selected
|
|---|
| 789 |
|
|---|
| 790 | > 2dlabels text "Binding Energy: -9.1 kcal/mol" color red size 18 xpos .03
|
|---|
| 791 | > ypos .95
|
|---|
| 792 |
|
|---|
| 793 | > 2dlabels text "3CO6 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 794 |
|
|---|
| 795 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3CO6--
|
|---|
| 796 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 797 | > true
|
|---|
| 798 |
|
|---|
| 799 | > select :UNL
|
|---|
| 800 |
|
|---|
| 801 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 802 |
|
|---|
| 803 | > view sel
|
|---|
| 804 |
|
|---|
| 805 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3CO6--
|
|---|
| 806 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 807 | > true
|
|---|
| 808 |
|
|---|
| 809 | > close
|
|---|
| 810 |
|
|---|
| 811 | > wait 5
|
|---|
| 812 |
|
|---|
| 813 | > set bgColor white
|
|---|
| 814 |
|
|---|
| 815 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1D7G.pdbqt
|
|---|
| 816 |
|
|---|
| 817 | Chain information for 1D7G.pdbqt #1
|
|---|
| 818 | ---
|
|---|
| 819 | Chain | Description
|
|---|
| 820 | A | No description available
|
|---|
| 821 | B | No description available
|
|---|
| 822 | C | No description available
|
|---|
| 823 | D | No description available
|
|---|
| 824 |
|
|---|
| 825 | Opened 1D7G.pdbqt containing 1 structures (2929 atoms, 3008 bonds)
|
|---|
| 826 |
|
|---|
| 827 | > wait 5
|
|---|
| 828 |
|
|---|
| 829 | > hide surfaces
|
|---|
| 830 |
|
|---|
| 831 | > hide atoms
|
|---|
| 832 |
|
|---|
| 833 | > show cartoons
|
|---|
| 834 |
|
|---|
| 835 | > wait 5
|
|---|
| 836 |
|
|---|
| 837 | > addh
|
|---|
| 838 |
|
|---|
| 839 | Summary of feedback from adding hydrogens to 1D7G.pdbqt #1
|
|---|
| 840 | ---
|
|---|
| 841 | warnings | Not adding hydrogens to /A G 5 C2' because it is missing heavy-atom
|
|---|
| 842 | bond partners
|
|---|
| 843 | Not adding hydrogens to /A C 6 C2' because it is missing heavy-atom bond
|
|---|
| 844 | partners
|
|---|
| 845 | Not adding hydrogens to /A C 7 C2' because it is missing heavy-atom bond
|
|---|
| 846 | partners
|
|---|
| 847 | Not adding hydrogens to /A C 8 C2' because it is missing heavy-atom bond
|
|---|
| 848 | partners
|
|---|
| 849 | Not adding hydrogens to /A A 10 C2' because it is missing heavy-atom bond
|
|---|
| 850 | partners
|
|---|
| 851 | 19 messages similar to the above omitted
|
|---|
| 852 | notes | No usable SEQRES records for 1D7G.pdbqt (#1) chain A; guessing termini
|
|---|
| 853 | instead
|
|---|
| 854 | No usable SEQRES records for 1D7G.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 855 | No usable SEQRES records for 1D7G.pdbqt (#1) chain C; guessing termini instead
|
|---|
| 856 | No usable SEQRES records for 1D7G.pdbqt (#1) chain D; guessing termini instead
|
|---|
| 857 | Chain-initial residues that are actual N termini: /A G 5, /B G 5, /C GLU 1, /D
|
|---|
| 858 | SER 1
|
|---|
| 859 | Chain-initial residues that are not actual N termini:
|
|---|
| 860 | Chain-final residues that are actual C termini: /A C 18, /B C 18, /C THR 59,
|
|---|
| 861 | /D LEU 59
|
|---|
| 862 | Chain-final residues that are not actual C termini:
|
|---|
| 863 | 153 hydrogen bonds
|
|---|
| 864 | 4 hydrogens added
|
|---|
| 865 |
|
|---|
| 866 |
|
|---|
| 867 | > wait 5
|
|---|
| 868 |
|
|---|
| 869 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1D7G--
|
|---|
| 870 | > WRM-16.result.pdbqt
|
|---|
| 871 |
|
|---|
| 872 | Summary of feedback from opening
|
|---|
| 873 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1D7G--WRM-16.result.pdbqt
|
|---|
| 874 | ---
|
|---|
| 875 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 876 | REMARK VINA RESULT: -7.9 0.000 0.000
|
|---|
| 877 |
|
|---|
| 878 | Ignored bad PDB record found on line 3
|
|---|
| 879 | REMARK 5 active torsions:
|
|---|
| 880 |
|
|---|
| 881 | Ignored bad PDB record found on line 4
|
|---|
| 882 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 883 |
|
|---|
| 884 | Ignored bad PDB record found on line 5
|
|---|
| 885 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 886 |
|
|---|
| 887 | Ignored bad PDB record found on line 6
|
|---|
| 888 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 889 |
|
|---|
| 890 | 184 messages similar to the above omitted
|
|---|
| 891 |
|
|---|
| 892 | Opened 1D7G--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 893 | bonds)
|
|---|
| 894 |
|
|---|
| 895 | > wait 5
|
|---|
| 896 |
|
|---|
| 897 | > close #2.2-9
|
|---|
| 898 |
|
|---|
| 899 | > wait 5
|
|---|
| 900 |
|
|---|
| 901 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 902 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1D7G--
|
|---|
| 903 | > WRM-16.contacts.txt
|
|---|
| 904 |
|
|---|
| 905 |
|
|---|
| 906 | Allowed overlap: -0.4
|
|---|
| 907 | H-bond overlap reduction: 0.4
|
|---|
| 908 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 909 | Detect intra-residue contacts: False
|
|---|
| 910 | Detect intra-molecule contacts: True
|
|---|
| 911 |
|
|---|
| 912 | 39 contacts
|
|---|
| 913 | atom1 atom2 overlap distance
|
|---|
| 914 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/D ARG 4 HE 0.329 2.431
|
|---|
| 915 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/B G 15 1H2' 0.256 2.624
|
|---|
| 916 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/D LYS 5 HG1 0.119 2.641
|
|---|
| 917 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 O 1D7G.pdbqt #1/D ARG 4 2HH1 0.015 2.005
|
|---|
| 918 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/D ARG 4 NE -0.009 3.394
|
|---|
| 919 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1D7G.pdbqt #1/D LYS 5 CG -0.009 3.589
|
|---|
| 920 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/D ARG 4 HB2 -0.018 2.778
|
|---|
| 921 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 O 1D7G.pdbqt #1/B G 17 H7 -0.024 2.044
|
|---|
| 922 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 O 1D7G.pdbqt #1/B G 16 H7 -0.025 2.045
|
|---|
| 923 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1D7G.pdbqt #1/D LYS 5 HG1 -0.045 2.925
|
|---|
| 924 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/B G 16 H7 -0.079 2.959
|
|---|
| 925 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 O 1D7G.pdbqt #1/D ARG 4 CZ -0.085 3.245
|
|---|
| 926 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/B G 15 C2' -0.096 3.676
|
|---|
| 927 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1D7G.pdbqt #1/D SER 1 O -0.112 3.472
|
|---|
| 928 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/D ARG 4 2HH1 -0.121 2.731
|
|---|
| 929 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/D ARG 4 HB2 -0.137 2.897
|
|---|
| 930 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/B G 16 N7 -0.144 3.649
|
|---|
| 931 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/B C 18 H41 -0.162 3.042
|
|---|
| 932 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/D ARG 4 NH1 -0.162 3.397
|
|---|
| 933 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/B G 17 H7 -0.174 2.784
|
|---|
| 934 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 O 1D7G.pdbqt #1/B G 15 C8 -0.195 3.315
|
|---|
| 935 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/D LYS 5 HG1 -0.207 2.817
|
|---|
| 936 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 O 1D7G.pdbqt #1/D ARG 4 NH1 -0.209 2.894
|
|---|
| 937 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/B G 16 H7 -0.210 2.820
|
|---|
| 938 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 O 1D7G.pdbqt #1/B G 17 C8 -0.227 3.387
|
|---|
| 939 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/B G 16 C8 -0.227 3.807
|
|---|
| 940 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/D LYS 5 CG -0.232 3.692
|
|---|
| 941 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/B G 16 N7 -0.234 3.469
|
|---|
| 942 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 O 1D7G.pdbqt #1/B G 16 O2P -0.237 3.197
|
|---|
| 943 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/D ARG 4 CB -0.252 3.712
|
|---|
| 944 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/D LYS 5 N -0.277 3.662
|
|---|
| 945 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/B G 16 O2P -0.310 3.570
|
|---|
| 946 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/B G 16 H8 -0.331 3.211
|
|---|
| 947 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 O 1D7G.pdbqt #1/D ARG 4 NH1 -0.333 2.978
|
|---|
| 948 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/B G 15 C8 -0.337 3.647
|
|---|
| 949 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 C 1D7G.pdbqt #1/D ARG 4 HE -0.343 2.953
|
|---|
| 950 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 O 1D7G.pdbqt #1/B G 16 N7 -0.347 2.992
|
|---|
| 951 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 O 1D7G.pdbqt #1/B G 17 N7 -0.366 3.011
|
|---|
| 952 | 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 O 1D7G.pdbqt #1/B G 17 O6 -0.397 3.297
|
|---|
| 953 |
|
|---|
| 954 |
|
|---|
| 955 |
|
|---|
| 956 | 39 contacts
|
|---|
| 957 |
|
|---|
| 958 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 959 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1D7G--
|
|---|
| 960 | > WRM-16.hbonds.txt
|
|---|
| 961 |
|
|---|
| 962 |
|
|---|
| 963 | Finding intermodel H-bonds
|
|---|
| 964 | Finding intramodel H-bonds
|
|---|
| 965 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 966 | Models used:
|
|---|
| 967 | 1 1D7G.pdbqt
|
|---|
| 968 | 2.1 1D7G--WRM-16.result.pdbqt
|
|---|
| 969 |
|
|---|
| 970 | 3 H-bonds
|
|---|
| 971 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 972 | 1D7G.pdbqt #1/B G 16 N7 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 O 1D7G.pdbqt #1/B G 16 H7 2.992 2.045
|
|---|
| 973 | 1D7G.pdbqt #1/B G 17 N7 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 O 1D7G.pdbqt #1/B G 17 H7 3.011 2.044
|
|---|
| 974 | 1D7G.pdbqt #1/D ARG 4 NH1 1D7G--WRM-16.result.pdbqt #2.1/? UNL 1 O 1D7G.pdbqt #1/D ARG 4 2HH1 2.978 2.005
|
|---|
| 975 |
|
|---|
| 976 |
|
|---|
| 977 |
|
|---|
| 978 | 3 hydrogen bonds found
|
|---|
| 979 |
|
|---|
| 980 | > select :UNL
|
|---|
| 981 |
|
|---|
| 982 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 983 |
|
|---|
| 984 | > label sel text "Ligand "
|
|---|
| 985 |
|
|---|
| 986 | > label height 1
|
|---|
| 987 |
|
|---|
| 988 | > ~select
|
|---|
| 989 |
|
|---|
| 990 | Nothing selected
|
|---|
| 991 |
|
|---|
| 992 | > 2dlabels text "Binding Energy: -7.9 kcal/mol" color red size 18 xpos .03
|
|---|
| 993 | > ypos .95
|
|---|
| 994 |
|
|---|
| 995 | > 2dlabels text "1D7G WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 996 |
|
|---|
| 997 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1D7G--
|
|---|
| 998 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 999 | > true
|
|---|
| 1000 |
|
|---|
| 1001 | > select :UNL
|
|---|
| 1002 |
|
|---|
| 1003 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 1004 |
|
|---|
| 1005 | > view sel
|
|---|
| 1006 |
|
|---|
| 1007 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1D7G--
|
|---|
| 1008 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 1009 | > true
|
|---|
| 1010 |
|
|---|
| 1011 | > close
|
|---|
| 1012 |
|
|---|
| 1013 | > wait 5
|
|---|
| 1014 |
|
|---|
| 1015 | > set bgColor white
|
|---|
| 1016 |
|
|---|
| 1017 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1GXC.pdbqt
|
|---|
| 1018 |
|
|---|
| 1019 | Chain information for 1GXC.pdbqt #1
|
|---|
| 1020 | ---
|
|---|
| 1021 | Chain | Description
|
|---|
| 1022 | A D G J | No description available
|
|---|
| 1023 | B E H K | No description available
|
|---|
| 1024 |
|
|---|
| 1025 | Opened 1GXC.pdbqt containing 1 structures (8116 atoms, 8224 bonds)
|
|---|
| 1026 |
|
|---|
| 1027 | > wait 5
|
|---|
| 1028 |
|
|---|
| 1029 | > hide surfaces
|
|---|
| 1030 |
|
|---|
| 1031 | > hide atoms
|
|---|
| 1032 |
|
|---|
| 1033 | > show cartoons
|
|---|
| 1034 |
|
|---|
| 1035 | > wait 5
|
|---|
| 1036 |
|
|---|
| 1037 | > addh
|
|---|
| 1038 |
|
|---|
| 1039 | Summary of feedback from adding hydrogens to 1GXC.pdbqt #1
|
|---|
| 1040 | ---
|
|---|
| 1041 | warnings | Not adding hydrogens to /A ASP 111 CB because it is missing heavy-
|
|---|
| 1042 | atom bond partners
|
|---|
| 1043 | Not adding hydrogens to /D ASP 111 CB because it is missing heavy-atom bond
|
|---|
| 1044 | partners
|
|---|
| 1045 | Not adding hydrogens to /G ASP 111 CB because it is missing heavy-atom bond
|
|---|
| 1046 | partners
|
|---|
| 1047 | Not adding hydrogens to /H ARG 7 CB because it is missing heavy-atom bond
|
|---|
| 1048 | partners
|
|---|
| 1049 | Not adding hydrogens to /J ASP 111 CB because it is missing heavy-atom bond
|
|---|
| 1050 | partners
|
|---|
| 1051 | 1 messages similar to the above omitted
|
|---|
| 1052 | notes | No usable SEQRES records for 1GXC.pdbqt (#1) chain A; guessing termini
|
|---|
| 1053 | instead
|
|---|
| 1054 | No usable SEQRES records for 1GXC.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 1055 | No usable SEQRES records for 1GXC.pdbqt (#1) chain D; guessing termini instead
|
|---|
| 1056 | No usable SEQRES records for 1GXC.pdbqt (#1) chain E; guessing termini instead
|
|---|
| 1057 | No usable SEQRES records for 1GXC.pdbqt (#1) chain G; guessing termini instead
|
|---|
| 1058 | 3 messages similar to the above omitted
|
|---|
| 1059 | Chain-initial residues that are actual N termini: /A PRO 92, /B HIS 0, /D PRO
|
|---|
| 1060 | 92, /E HIS 0, /G PRO 92, /H HIS 0, /J PRO 92, /K HIS 0
|
|---|
| 1061 | Chain-initial residues that are not actual N termini: /B TYR 4, /E TYR 4, /H
|
|---|
| 1062 | TYR 4, /K TYR 4
|
|---|
| 1063 | Chain-final residues that are actual C termini: /A ASP 207, /B ARG 7, /D ASP
|
|---|
| 1064 | 207, /E ARG 7, /G ASP 207, /H ARG 7, /J ASP 207, /K ARG 7
|
|---|
| 1065 | Chain-final residues that are not actual C termini: /B ASP 2, /E ASP 2, /H ASP
|
|---|
| 1066 | 2, /K ASP 2
|
|---|
| 1067 | 388 hydrogen bonds
|
|---|
| 1068 | Adding 'H' to /B TYR 4
|
|---|
| 1069 | Adding 'H' to /E TYR 4
|
|---|
| 1070 | Adding 'H' to /H TYR 4
|
|---|
| 1071 | Adding 'H' to /K TYR 4
|
|---|
| 1072 | /B ASP 2 is not terminus, removing H atom from 'C'
|
|---|
| 1073 | /E ASP 2 is not terminus, removing H atom from 'C'
|
|---|
| 1074 | /H ASP 2 is not terminus, removing H atom from 'C'
|
|---|
| 1075 | /K ASP 2 is not terminus, removing H atom from 'C'
|
|---|
| 1076 | 0 hydrogens added
|
|---|
| 1077 |
|
|---|
| 1078 |
|
|---|
| 1079 | > wait 5
|
|---|
| 1080 |
|
|---|
| 1081 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1GXC--
|
|---|
| 1082 | > WRM-16.result.pdbqt
|
|---|
| 1083 |
|
|---|
| 1084 | Summary of feedback from opening
|
|---|
| 1085 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1GXC--WRM-16.result.pdbqt
|
|---|
| 1086 | ---
|
|---|
| 1087 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 1088 | REMARK VINA RESULT: -7.0 0.000 0.000
|
|---|
| 1089 |
|
|---|
| 1090 | Ignored bad PDB record found on line 3
|
|---|
| 1091 | REMARK 5 active torsions:
|
|---|
| 1092 |
|
|---|
| 1093 | Ignored bad PDB record found on line 4
|
|---|
| 1094 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 1095 |
|
|---|
| 1096 | Ignored bad PDB record found on line 5
|
|---|
| 1097 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 1098 |
|
|---|
| 1099 | Ignored bad PDB record found on line 6
|
|---|
| 1100 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 1101 |
|
|---|
| 1102 | 184 messages similar to the above omitted
|
|---|
| 1103 |
|
|---|
| 1104 | Opened 1GXC--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 1105 | bonds)
|
|---|
| 1106 |
|
|---|
| 1107 | > wait 5
|
|---|
| 1108 |
|
|---|
| 1109 | > close #2.2-9
|
|---|
| 1110 |
|
|---|
| 1111 | > wait 5
|
|---|
| 1112 |
|
|---|
| 1113 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 1114 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1GXC--
|
|---|
| 1115 | > WRM-16.contacts.txt
|
|---|
| 1116 |
|
|---|
| 1117 |
|
|---|
| 1118 | Allowed overlap: -0.4
|
|---|
| 1119 | H-bond overlap reduction: 0.4
|
|---|
| 1120 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 1121 | Detect intra-residue contacts: False
|
|---|
| 1122 | Detect intra-molecule contacts: True
|
|---|
| 1123 |
|
|---|
| 1124 | 30 contacts
|
|---|
| 1125 | atom1 atom2 overlap distance
|
|---|
| 1126 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/D ASN 184 HB2 0.193 2.567
|
|---|
| 1127 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/G LEU 129 HA 0.144 2.736
|
|---|
| 1128 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/G LEU 129 3HD1 0.103 2.657
|
|---|
| 1129 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1GXC.pdbqt #1/D ASN 185 HN 0.074 2.806
|
|---|
| 1130 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1GXC.pdbqt #1/D ASN 185 HB2 0.014 2.866
|
|---|
| 1131 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/G LEU 129 HA -0.111 2.721
|
|---|
| 1132 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1GXC.pdbqt #1/D ASN 185 CB -0.140 3.720
|
|---|
| 1133 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/G LEU 129 CA -0.141 3.721
|
|---|
| 1134 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/D ASN 186 O -0.141 3.381
|
|---|
| 1135 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/G LEU 129 3HD1 -0.151 2.761
|
|---|
| 1136 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 O 1GXC.pdbqt #1/G ARG 132 HD1 -0.159 2.619
|
|---|
| 1137 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/D ASN 185 O -0.179 3.539
|
|---|
| 1138 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/D ASN 184 CB -0.181 3.641
|
|---|
| 1139 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/D ASN 185 N -0.199 3.584
|
|---|
| 1140 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/D ASN 185 HB2 -0.204 2.964
|
|---|
| 1141 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 O 1GXC.pdbqt #1/G LEU 129 HA -0.211 2.631
|
|---|
| 1142 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/D ASN 185 O -0.218 3.458
|
|---|
| 1143 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 O 1GXC.pdbqt #1/G ARG 132 CD -0.232 3.392
|
|---|
| 1144 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/D ASN 186 HB1 -0.235 2.995
|
|---|
| 1145 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 O 1GXC.pdbqt #1/G LEU 129 O -0.252 3.152
|
|---|
| 1146 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/D ASN 185 HN -0.264 3.024
|
|---|
| 1147 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/G LEU 129 CD1 -0.264 3.724
|
|---|
| 1148 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1GXC.pdbqt #1/D ASN 185 N -0.278 3.783
|
|---|
| 1149 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/G LEU 129 3HD1 -0.301 3.061
|
|---|
| 1150 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/G LEU 129 HB1 -0.310 3.070
|
|---|
| 1151 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/G LEU 129 N -0.338 3.843
|
|---|
| 1152 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/G LEU 129 CD1 -0.354 3.664
|
|---|
| 1153 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/G ARG 132 HD1 -0.355 3.235
|
|---|
| 1154 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 O 1GXC.pdbqt #1/D ASN 186 HB2 -0.377 2.837
|
|---|
| 1155 | 1GXC--WRM-16.result.pdbqt #2.1/? UNL 1 C 1GXC.pdbqt #1/G LEU 129 CD1 -0.396 3.856
|
|---|
| 1156 |
|
|---|
| 1157 |
|
|---|
| 1158 |
|
|---|
| 1159 | 30 contacts
|
|---|
| 1160 |
|
|---|
| 1161 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 1162 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1GXC--
|
|---|
| 1163 | > WRM-16.hbonds.txt
|
|---|
| 1164 |
|
|---|
| 1165 |
|
|---|
| 1166 | Finding intermodel H-bonds
|
|---|
| 1167 | Finding intramodel H-bonds
|
|---|
| 1168 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 1169 | Models used:
|
|---|
| 1170 | 1 1GXC.pdbqt
|
|---|
| 1171 | 2.1 1GXC--WRM-16.result.pdbqt
|
|---|
| 1172 |
|
|---|
| 1173 | 0 H-bonds
|
|---|
| 1174 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 1175 |
|
|---|
| 1176 |
|
|---|
| 1177 |
|
|---|
| 1178 | 0 hydrogen bonds found
|
|---|
| 1179 |
|
|---|
| 1180 | > select :UNL
|
|---|
| 1181 |
|
|---|
| 1182 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 1183 |
|
|---|
| 1184 | > label sel text "Ligand "
|
|---|
| 1185 |
|
|---|
| 1186 | > label height 1
|
|---|
| 1187 |
|
|---|
| 1188 | > ~select
|
|---|
| 1189 |
|
|---|
| 1190 | Nothing selected
|
|---|
| 1191 |
|
|---|
| 1192 | > 2dlabels text "Binding Energy: -7.0 kcal/mol" color red size 18 xpos .03
|
|---|
| 1193 | > ypos .95
|
|---|
| 1194 |
|
|---|
| 1195 | > 2dlabels text "1GXC WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 1196 |
|
|---|
| 1197 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1GXC--
|
|---|
| 1198 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 1199 | > true
|
|---|
| 1200 |
|
|---|
| 1201 | > select :UNL
|
|---|
| 1202 |
|
|---|
| 1203 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 1204 |
|
|---|
| 1205 | > view sel
|
|---|
| 1206 |
|
|---|
| 1207 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1GXC--
|
|---|
| 1208 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 1209 | > true
|
|---|
| 1210 |
|
|---|
| 1211 | > close
|
|---|
| 1212 |
|
|---|
| 1213 | > wait 5
|
|---|
| 1214 |
|
|---|
| 1215 | > set bgColor white
|
|---|
| 1216 |
|
|---|
| 1217 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1KO6.pdbqt
|
|---|
| 1218 |
|
|---|
| 1219 | Chain information for 1KO6.pdbqt #1
|
|---|
| 1220 | ---
|
|---|
| 1221 | Chain | Description
|
|---|
| 1222 | A | No description available
|
|---|
| 1223 | B D | No description available
|
|---|
| 1224 | C | No description available
|
|---|
| 1225 |
|
|---|
| 1226 | Opened 1KO6.pdbqt containing 1 structures (4955 atoms, 5004 bonds)
|
|---|
| 1227 |
|
|---|
| 1228 | > wait 5
|
|---|
| 1229 |
|
|---|
| 1230 | > hide surfaces
|
|---|
| 1231 |
|
|---|
| 1232 | > hide atoms
|
|---|
| 1233 |
|
|---|
| 1234 | > show cartoons
|
|---|
| 1235 |
|
|---|
| 1236 | > wait 5
|
|---|
| 1237 |
|
|---|
| 1238 | > addh
|
|---|
| 1239 |
|
|---|
| 1240 | Summary of feedback from adding hydrogens to 1KO6.pdbqt #1
|
|---|
| 1241 | ---
|
|---|
| 1242 | warnings | Not adding hydrogens to /A MET 712 CB because it is missing heavy-
|
|---|
| 1243 | atom bond partners
|
|---|
| 1244 | Not adding hydrogens to /A LYS 814 CB because it is missing heavy-atom bond
|
|---|
| 1245 | partners
|
|---|
| 1246 | Not adding hydrogens to /C THR 737 CB because it is missing heavy-atom bond
|
|---|
| 1247 | partners
|
|---|
| 1248 | Not adding hydrogens to /D ASP 870 CB because it is missing heavy-atom bond
|
|---|
| 1249 | partners
|
|---|
| 1250 | notes | No usable SEQRES records for 1KO6.pdbqt (#1) chain A; guessing termini
|
|---|
| 1251 | instead
|
|---|
| 1252 | No usable SEQRES records for 1KO6.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 1253 | No usable SEQRES records for 1KO6.pdbqt (#1) chain C; guessing termini instead
|
|---|
| 1254 | No usable SEQRES records for 1KO6.pdbqt (#1) chain D; guessing termini instead
|
|---|
| 1255 | Chain-initial residues that are actual N termini: /A MET 712, /B LYS 865, /C
|
|---|
| 1256 | HIS 713, /D LYS 865
|
|---|
| 1257 | Chain-initial residues that are not actual N termini: /C GLU 742
|
|---|
| 1258 | Chain-final residues that are actual C termini: /A PHE 863, /B ASP 870, /C PHE
|
|---|
| 1259 | 863, /D ASP 870
|
|---|
| 1260 | Chain-final residues that are not actual C termini: /C ASN 738
|
|---|
| 1261 | 223 hydrogen bonds
|
|---|
| 1262 | Adding 'H' to /C GLU 742
|
|---|
| 1263 | /C ASN 738 is not terminus, removing H atom from 'C'
|
|---|
| 1264 | 1 hydrogens added
|
|---|
| 1265 |
|
|---|
| 1266 |
|
|---|
| 1267 | > wait 5
|
|---|
| 1268 |
|
|---|
| 1269 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1KO6--
|
|---|
| 1270 | > WRM-16.result.pdbqt
|
|---|
| 1271 |
|
|---|
| 1272 | Summary of feedback from opening
|
|---|
| 1273 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1KO6--WRM-16.result.pdbqt
|
|---|
| 1274 | ---
|
|---|
| 1275 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 1276 | REMARK VINA RESULT: -7.3 0.000 0.000
|
|---|
| 1277 |
|
|---|
| 1278 | Ignored bad PDB record found on line 3
|
|---|
| 1279 | REMARK 5 active torsions:
|
|---|
| 1280 |
|
|---|
| 1281 | Ignored bad PDB record found on line 4
|
|---|
| 1282 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 1283 |
|
|---|
| 1284 | Ignored bad PDB record found on line 5
|
|---|
| 1285 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 1286 |
|
|---|
| 1287 | Ignored bad PDB record found on line 6
|
|---|
| 1288 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 1289 |
|
|---|
| 1290 | 184 messages similar to the above omitted
|
|---|
| 1291 |
|
|---|
| 1292 | Opened 1KO6--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 1293 | bonds)
|
|---|
| 1294 |
|
|---|
| 1295 | > wait 5
|
|---|
| 1296 |
|
|---|
| 1297 | > close #2.2-9
|
|---|
| 1298 |
|
|---|
| 1299 | > wait 5
|
|---|
| 1300 |
|
|---|
| 1301 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 1302 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1KO6--
|
|---|
| 1303 | > WRM-16.contacts.txt
|
|---|
| 1304 |
|
|---|
| 1305 |
|
|---|
| 1306 | Allowed overlap: -0.4
|
|---|
| 1307 | H-bond overlap reduction: 0.4
|
|---|
| 1308 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 1309 | Detect intra-residue contacts: False
|
|---|
| 1310 | Detect intra-molecule contacts: True
|
|---|
| 1311 |
|
|---|
| 1312 | 36 contacts
|
|---|
| 1313 | atom1 atom2 overlap distance
|
|---|
| 1314 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A LEU 786 3HD2 0.149 2.461
|
|---|
| 1315 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A LEU 786 3HD2 0.075 2.535
|
|---|
| 1316 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A LEU 786 HB2 0.038 2.722
|
|---|
| 1317 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A LEU 786 HB2 0.022 2.738
|
|---|
| 1318 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A LEU 786 3HD2 -0.109 2.869
|
|---|
| 1319 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A VAL 783 2HG1 -0.121 2.731
|
|---|
| 1320 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A ARG 778 NH2 -0.144 3.649
|
|---|
| 1321 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A LEU 786 CD2 -0.149 3.459
|
|---|
| 1322 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A HIS 776 CE1 -0.153 3.613
|
|---|
| 1323 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A HIS 776 HD1 -0.165 2.925
|
|---|
| 1324 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A LEU 786 C -0.168 3.628
|
|---|
| 1325 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/C GLU 848 OE2 -0.172 3.412
|
|---|
| 1326 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A HIS 776 HD1 -0.179 2.939
|
|---|
| 1327 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A ARG 778 CZ -0.190 3.770
|
|---|
| 1328 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A ARG 778 CZ -0.200 3.780
|
|---|
| 1329 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 1KO6.pdbqt #1/A ARG 778 CZ -0.201 3.361
|
|---|
| 1330 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 1KO6.pdbqt #1/A LEU 786 3HD2 -0.234 2.694
|
|---|
| 1331 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A HIS 776 ND1 -0.236 3.621
|
|---|
| 1332 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A LEU 786 CD2 -0.243 3.553
|
|---|
| 1333 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A HIS 776 HE1 -0.244 3.004
|
|---|
| 1334 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A LEU 786 C -0.255 3.715
|
|---|
| 1335 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A ARG 778 NE -0.258 3.763
|
|---|
| 1336 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A ASP 787 N -0.265 3.650
|
|---|
| 1337 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 O 1KO6.pdbqt #1/A ARG 778 CZ -0.299 3.419
|
|---|
| 1338 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A HIS 776 ND1 -0.302 3.687
|
|---|
| 1339 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A ASP 787 HB2 -0.308 3.068
|
|---|
| 1340 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A ASP 787 HB2 -0.317 3.077
|
|---|
| 1341 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/C ARG 850 HD1 -0.328 3.088
|
|---|
| 1342 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/C ARG 850 CD -0.334 3.794
|
|---|
| 1343 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A HIS 776 CE1 -0.338 3.798
|
|---|
| 1344 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A ASP 787 CB -0.340 3.800
|
|---|
| 1345 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A LEU 786 CB -0.345 3.805
|
|---|
| 1346 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A LEU 786 O -0.353 3.593
|
|---|
| 1347 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A VAL 783 CG1 -0.358 3.668
|
|---|
| 1348 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A LEU 786 CB -0.362 3.822
|
|---|
| 1349 | 1KO6--WRM-16.result.pdbqt #2.1/? UNL 1 C 1KO6.pdbqt #1/A LEU 786 HB2 -0.365 3.125
|
|---|
| 1350 |
|
|---|
| 1351 |
|
|---|
| 1352 |
|
|---|
| 1353 | 36 contacts
|
|---|
| 1354 |
|
|---|
| 1355 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 1356 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1KO6--
|
|---|
| 1357 | > WRM-16.hbonds.txt
|
|---|
| 1358 |
|
|---|
| 1359 |
|
|---|
| 1360 | Finding intermodel H-bonds
|
|---|
| 1361 | Finding intramodel H-bonds
|
|---|
| 1362 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 1363 | Models used:
|
|---|
| 1364 | 1 1KO6.pdbqt
|
|---|
| 1365 | 2.1 1KO6--WRM-16.result.pdbqt
|
|---|
| 1366 |
|
|---|
| 1367 | 0 H-bonds
|
|---|
| 1368 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 1369 |
|
|---|
| 1370 |
|
|---|
| 1371 |
|
|---|
| 1372 | 0 hydrogen bonds found
|
|---|
| 1373 |
|
|---|
| 1374 | > select :UNL
|
|---|
| 1375 |
|
|---|
| 1376 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 1377 |
|
|---|
| 1378 | > label sel text "Ligand "
|
|---|
| 1379 |
|
|---|
| 1380 | > label height 1
|
|---|
| 1381 |
|
|---|
| 1382 | > ~select
|
|---|
| 1383 |
|
|---|
| 1384 | Nothing selected
|
|---|
| 1385 |
|
|---|
| 1386 | > 2dlabels text "Binding Energy: -7.3 kcal/mol" color red size 18 xpos .03
|
|---|
| 1387 | > ypos .95
|
|---|
| 1388 |
|
|---|
| 1389 | > 2dlabels text "1KO6 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 1390 |
|
|---|
| 1391 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1KO6--
|
|---|
| 1392 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 1393 | > true
|
|---|
| 1394 |
|
|---|
| 1395 | > select :UNL
|
|---|
| 1396 |
|
|---|
| 1397 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 1398 |
|
|---|
| 1399 | > view sel
|
|---|
| 1400 |
|
|---|
| 1401 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1KO6--
|
|---|
| 1402 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 1403 | > true
|
|---|
| 1404 |
|
|---|
| 1405 | > close
|
|---|
| 1406 |
|
|---|
| 1407 | > wait 5
|
|---|
| 1408 |
|
|---|
| 1409 | > set bgColor white
|
|---|
| 1410 |
|
|---|
| 1411 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/2I2Y.pdbqt
|
|---|
| 1412 |
|
|---|
| 1413 | Chain information for 2I2Y.pdbqt #1
|
|---|
| 1414 | ---
|
|---|
| 1415 | Chain | Description
|
|---|
| 1416 | A | No description available
|
|---|
| 1417 | B | No description available
|
|---|
| 1418 |
|
|---|
| 1419 | Opened 2I2Y.pdbqt containing 1 structures (2441 atoms, 2472 bonds)
|
|---|
| 1420 |
|
|---|
| 1421 | > wait 5
|
|---|
| 1422 |
|
|---|
| 1423 | > hide surfaces
|
|---|
| 1424 |
|
|---|
| 1425 | > hide atoms
|
|---|
| 1426 |
|
|---|
| 1427 | > show cartoons
|
|---|
| 1428 |
|
|---|
| 1429 | > wait 5
|
|---|
| 1430 |
|
|---|
| 1431 | > addh
|
|---|
| 1432 |
|
|---|
| 1433 | Summary of feedback from adding hydrogens to 2I2Y.pdbqt #1
|
|---|
| 1434 | ---
|
|---|
| 1435 | notes | No usable SEQRES records for 2I2Y.pdbqt (#1) chain A; guessing termini
|
|---|
| 1436 | instead
|
|---|
| 1437 | No usable SEQRES records for 2I2Y.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 1438 | Chain-initial residues that are actual N termini: /A MET 1, /B C 151
|
|---|
| 1439 | Chain-initial residues that are not actual N termini:
|
|---|
| 1440 | Chain-final residues that are actual C termini: /A ARG 150, /B C 154
|
|---|
| 1441 | Chain-final residues that are not actual C termini:
|
|---|
| 1442 | 171 hydrogen bonds
|
|---|
| 1443 | 10 hydrogens added
|
|---|
| 1444 |
|
|---|
| 1445 |
|
|---|
| 1446 | > wait 5
|
|---|
| 1447 |
|
|---|
| 1448 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2I2Y--
|
|---|
| 1449 | > WRM-16.result.pdbqt
|
|---|
| 1450 |
|
|---|
| 1451 | Summary of feedback from opening
|
|---|
| 1452 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2I2Y--WRM-16.result.pdbqt
|
|---|
| 1453 | ---
|
|---|
| 1454 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 1455 | REMARK VINA RESULT: -6.7 0.000 0.000
|
|---|
| 1456 |
|
|---|
| 1457 | Ignored bad PDB record found on line 3
|
|---|
| 1458 | REMARK 5 active torsions:
|
|---|
| 1459 |
|
|---|
| 1460 | Ignored bad PDB record found on line 4
|
|---|
| 1461 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 1462 |
|
|---|
| 1463 | Ignored bad PDB record found on line 5
|
|---|
| 1464 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 1465 |
|
|---|
| 1466 | Ignored bad PDB record found on line 6
|
|---|
| 1467 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 1468 |
|
|---|
| 1469 | 184 messages similar to the above omitted
|
|---|
| 1470 |
|
|---|
| 1471 | Opened 2I2Y--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 1472 | bonds)
|
|---|
| 1473 |
|
|---|
| 1474 | > wait 5
|
|---|
| 1475 |
|
|---|
| 1476 | > close #2.2-9
|
|---|
| 1477 |
|
|---|
| 1478 | > wait 5
|
|---|
| 1479 |
|
|---|
| 1480 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 1481 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2I2Y--
|
|---|
| 1482 | > WRM-16.contacts.txt
|
|---|
| 1483 |
|
|---|
| 1484 |
|
|---|
| 1485 | Allowed overlap: -0.4
|
|---|
| 1486 | H-bond overlap reduction: 0.4
|
|---|
| 1487 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 1488 | Detect intra-residue contacts: False
|
|---|
| 1489 | Detect intra-molecule contacts: True
|
|---|
| 1490 |
|
|---|
| 1491 | 42 contacts
|
|---|
| 1492 | atom1 atom2 overlap distance
|
|---|
| 1493 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ASP 73 O 0.082 3.158
|
|---|
| 1494 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ASP 73 HB3 0.042 2.568
|
|---|
| 1495 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A LEU 144 3HD1 0.038 2.722
|
|---|
| 1496 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A LEU 144 3HD2 0.018 2.592
|
|---|
| 1497 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A LEU 144 3HD2 0.002 2.608
|
|---|
| 1498 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A LEU 144 3HD2 -0.056 2.936
|
|---|
| 1499 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ALA 124 HA -0.087 2.847
|
|---|
| 1500 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ARG 128 HG2 -0.102 2.862
|
|---|
| 1501 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A LEU 144 3HD1 -0.104 2.864
|
|---|
| 1502 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ALA 124 N -0.108 3.613
|
|---|
| 1503 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ASP 73 HB3 -0.117 2.877
|
|---|
| 1504 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 O 2I2Y.pdbqt #1/A ASP 73 O -0.129 3.029
|
|---|
| 1505 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ALA 124 HA -0.132 3.012
|
|---|
| 1506 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A LEU 144 CD2 -0.137 3.717
|
|---|
| 1507 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ALA 124 CA -0.151 3.731
|
|---|
| 1508 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ALA 124 HB3 -0.156 2.916
|
|---|
| 1509 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A LEU 144 3HD2 -0.160 2.920
|
|---|
| 1510 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ASP 73 OD1 -0.177 3.417
|
|---|
| 1511 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ALA 124 HB3 -0.188 2.798
|
|---|
| 1512 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ALA 124 CB -0.194 3.504
|
|---|
| 1513 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ALA 123 C -0.215 3.795
|
|---|
| 1514 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2I2Y.pdbqt #1/A ARG 150 CZ -0.217 3.797
|
|---|
| 1515 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2I2Y.pdbqt #1/A ARG 150 NH1 -0.264 3.769
|
|---|
| 1516 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ALA 124 CB -0.268 3.578
|
|---|
| 1517 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ASP 73 HB3 -0.274 3.034
|
|---|
| 1518 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A LEU 144 CD1 -0.276 3.736
|
|---|
| 1519 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ALA 124 CB -0.297 3.877
|
|---|
| 1520 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A VAL 127 CG1 -0.301 3.761
|
|---|
| 1521 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A LEU 144 CD2 -0.306 3.616
|
|---|
| 1522 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A VAL 127 CG1 -0.313 3.773
|
|---|
| 1523 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ASP 73 HB3 -0.320 2.930
|
|---|
| 1524 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2I2Y.pdbqt #1/A ARG 150 NH2 -0.323 3.828
|
|---|
| 1525 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ARG 128 HG2 -0.332 3.092
|
|---|
| 1526 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ASP 68 O -0.337 3.577
|
|---|
| 1527 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ASP 73 CB -0.338 3.648
|
|---|
| 1528 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ALA 123 CB -0.338 3.918
|
|---|
| 1529 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ARG 128 CG -0.343 3.803
|
|---|
| 1530 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 O 2I2Y.pdbqt #1/A SER 69 OG -0.346 2.866
|
|---|
| 1531 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ALA 124 CA -0.358 3.818
|
|---|
| 1532 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A SER 69 OG -0.359 3.469
|
|---|
| 1533 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A LEU 144 CD2 -0.367 3.677
|
|---|
| 1534 | 2I2Y--WRM-16.result.pdbqt #2.1/? UNL 1 C 2I2Y.pdbqt #1/A ALA 123 HB2 -0.389 3.269
|
|---|
| 1535 |
|
|---|
| 1536 |
|
|---|
| 1537 |
|
|---|
| 1538 | 42 contacts
|
|---|
| 1539 |
|
|---|
| 1540 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 1541 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2I2Y--
|
|---|
| 1542 | > WRM-16.hbonds.txt
|
|---|
| 1543 |
|
|---|
| 1544 |
|
|---|
| 1545 | Finding intermodel H-bonds
|
|---|
| 1546 | Finding intramodel H-bonds
|
|---|
| 1547 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 1548 | Models used:
|
|---|
| 1549 | 1 2I2Y.pdbqt
|
|---|
| 1550 | 2.1 2I2Y--WRM-16.result.pdbqt
|
|---|
| 1551 |
|
|---|
| 1552 | 0 H-bonds
|
|---|
| 1553 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 1554 |
|
|---|
| 1555 |
|
|---|
| 1556 |
|
|---|
| 1557 | 0 hydrogen bonds found
|
|---|
| 1558 |
|
|---|
| 1559 | > select :UNL
|
|---|
| 1560 |
|
|---|
| 1561 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 1562 |
|
|---|
| 1563 | > label sel text "Ligand "
|
|---|
| 1564 |
|
|---|
| 1565 | > label height 1
|
|---|
| 1566 |
|
|---|
| 1567 | > ~select
|
|---|
| 1568 |
|
|---|
| 1569 | Nothing selected
|
|---|
| 1570 |
|
|---|
| 1571 | > 2dlabels text "Binding Energy: -6.7 kcal/mol" color red size 18 xpos .03
|
|---|
| 1572 | > ypos .95
|
|---|
| 1573 |
|
|---|
| 1574 | > 2dlabels text "2I2Y WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 1575 |
|
|---|
| 1576 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2I2Y--
|
|---|
| 1577 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 1578 | > true
|
|---|
| 1579 |
|
|---|
| 1580 | > select :UNL
|
|---|
| 1581 |
|
|---|
| 1582 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 1583 |
|
|---|
| 1584 | > view sel
|
|---|
| 1585 |
|
|---|
| 1586 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2I2Y--
|
|---|
| 1587 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 1588 | > true
|
|---|
| 1589 |
|
|---|
| 1590 | > close
|
|---|
| 1591 |
|
|---|
| 1592 | > wait 5
|
|---|
| 1593 |
|
|---|
| 1594 | > set bgColor white
|
|---|
| 1595 |
|
|---|
| 1596 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/2CPE.pdbqt
|
|---|
| 1597 |
|
|---|
| 1598 | Chain information for 2CPE.pdbqt #1
|
|---|
| 1599 | ---
|
|---|
| 1600 | Chain | Description
|
|---|
| 1601 | A | No description available
|
|---|
| 1602 |
|
|---|
| 1603 | Opened 2CPE.pdbqt containing 1 structures (1663 atoms, 1680 bonds)
|
|---|
| 1604 |
|
|---|
| 1605 | > wait 5
|
|---|
| 1606 |
|
|---|
| 1607 | > hide surfaces
|
|---|
| 1608 |
|
|---|
| 1609 | > hide atoms
|
|---|
| 1610 |
|
|---|
| 1611 | > show cartoons
|
|---|
| 1612 |
|
|---|
| 1613 | > wait 5
|
|---|
| 1614 |
|
|---|
| 1615 | > addh
|
|---|
| 1616 |
|
|---|
| 1617 | Summary of feedback from adding hydrogens to 2CPE.pdbqt #1
|
|---|
| 1618 | ---
|
|---|
| 1619 | notes | No usable SEQRES records for 2CPE.pdbqt (#1) chain A; guessing termini
|
|---|
| 1620 | instead
|
|---|
| 1621 | Chain-initial residues that are actual N termini: /A GLY 346
|
|---|
| 1622 | Chain-initial residues that are not actual N termini:
|
|---|
| 1623 | Chain-final residues that are actual C termini: /A GLY 458
|
|---|
| 1624 | Chain-final residues that are not actual C termini:
|
|---|
| 1625 | 43 hydrogen bonds
|
|---|
| 1626 | 1 hydrogens added
|
|---|
| 1627 |
|
|---|
| 1628 |
|
|---|
| 1629 | > wait 5
|
|---|
| 1630 |
|
|---|
| 1631 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2CPE--
|
|---|
| 1632 | > WRM-16.result.pdbqt
|
|---|
| 1633 |
|
|---|
| 1634 | Summary of feedback from opening
|
|---|
| 1635 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2CPE--WRM-16.result.pdbqt
|
|---|
| 1636 | ---
|
|---|
| 1637 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 1638 | REMARK VINA RESULT: -6.4 0.000 0.000
|
|---|
| 1639 |
|
|---|
| 1640 | Ignored bad PDB record found on line 3
|
|---|
| 1641 | REMARK 5 active torsions:
|
|---|
| 1642 |
|
|---|
| 1643 | Ignored bad PDB record found on line 4
|
|---|
| 1644 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 1645 |
|
|---|
| 1646 | Ignored bad PDB record found on line 5
|
|---|
| 1647 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 1648 |
|
|---|
| 1649 | Ignored bad PDB record found on line 6
|
|---|
| 1650 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 1651 |
|
|---|
| 1652 | 184 messages similar to the above omitted
|
|---|
| 1653 |
|
|---|
| 1654 | Opened 2CPE--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 1655 | bonds)
|
|---|
| 1656 |
|
|---|
| 1657 | > wait 5
|
|---|
| 1658 |
|
|---|
| 1659 | > close #2.2-9
|
|---|
| 1660 |
|
|---|
| 1661 | > wait 5
|
|---|
| 1662 |
|
|---|
| 1663 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 1664 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2CPE--
|
|---|
| 1665 | > WRM-16.contacts.txt
|
|---|
| 1666 |
|
|---|
| 1667 |
|
|---|
| 1668 | Allowed overlap: -0.4
|
|---|
| 1669 | H-bond overlap reduction: 0.4
|
|---|
| 1670 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 1671 | Detect intra-residue contacts: False
|
|---|
| 1672 | Detect intra-molecule contacts: True
|
|---|
| 1673 |
|
|---|
| 1674 | 45 contacts
|
|---|
| 1675 | atom1 atom2 overlap distance
|
|---|
| 1676 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A LEU 374 HB2 0.239 2.521
|
|---|
| 1677 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2CPE.pdbqt #1/A ILE 400 H 0.104 2.776
|
|---|
| 1678 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 HB 0.090 2.670
|
|---|
| 1679 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 O 2CPE.pdbqt #1/A VAL 372 O 0.010 2.930
|
|---|
| 1680 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 HB -0.008 2.768
|
|---|
| 1681 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2CPE.pdbqt #1/A HIS 399 ND1 -0.011 3.516
|
|---|
| 1682 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 O -0.023 3.263
|
|---|
| 1683 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 CD1 -0.043 3.503
|
|---|
| 1684 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 O 2CPE.pdbqt #1/A THR 373 2HG2 -0.051 2.511
|
|---|
| 1685 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2CPE.pdbqt #1/A HIS 399 CE1 -0.060 3.640
|
|---|
| 1686 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A LEU 374 CB -0.065 3.525
|
|---|
| 1687 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 2HD1 -0.072 2.832
|
|---|
| 1688 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 2HD1 -0.104 2.714
|
|---|
| 1689 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 O 2CPE.pdbqt #1/A LEU 374 H -0.106 2.126
|
|---|
| 1690 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A LEU 402 2HD2 -0.122 3.002
|
|---|
| 1691 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 2HD1 -0.144 2.754
|
|---|
| 1692 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A LEU 402 3HD1 -0.145 2.755
|
|---|
| 1693 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A VAL 372 O -0.165 3.525
|
|---|
| 1694 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A LEU 402 CD1 -0.165 3.625
|
|---|
| 1695 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A GLY 407 O -0.173 3.413
|
|---|
| 1696 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 HB -0.190 2.800
|
|---|
| 1697 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 O 2CPE.pdbqt #1/A LEU 402 3HD1 -0.198 2.658
|
|---|
| 1698 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2CPE.pdbqt #1/A ILE 400 N -0.226 3.731
|
|---|
| 1699 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 HB -0.233 2.993
|
|---|
| 1700 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 CB -0.257 3.717
|
|---|
| 1701 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 2HD1 -0.296 3.176
|
|---|
| 1702 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A LEU 402 CD1 -0.306 3.766
|
|---|
| 1703 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2CPE.pdbqt #1/A HIS 399 HA -0.312 3.192
|
|---|
| 1704 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 HB -0.326 3.086
|
|---|
| 1705 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A THR 373 2HG2 -0.326 3.206
|
|---|
| 1706 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 O 2CPE.pdbqt #1/A THR 373 HA -0.326 2.746
|
|---|
| 1707 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 H -0.328 2.938
|
|---|
| 1708 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A THR 373 HA -0.343 3.223
|
|---|
| 1709 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 CB -0.348 3.808
|
|---|
| 1710 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 CG1 -0.351 3.811
|
|---|
| 1711 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 HB -0.367 2.977
|
|---|
| 1712 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A LEU 374 HB2 -0.373 3.133
|
|---|
| 1713 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 O 2CPE.pdbqt #1/A THR 373 CG2 -0.376 3.536
|
|---|
| 1714 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 O 2CPE.pdbqt #1/A ASP 370 O -0.382 3.282
|
|---|
| 1715 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A LEU 402 1HD1 -0.384 3.144
|
|---|
| 1716 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 O 2CPE.pdbqt #1/A LEU 374 N -0.385 3.030
|
|---|
| 1717 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 CB -0.390 3.850
|
|---|
| 1718 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A GLY 407 O -0.392 3.632
|
|---|
| 1719 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A ILE 400 CD1 -0.398 3.708
|
|---|
| 1720 | 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CPE.pdbqt #1/A LEU 402 CD1 -0.400 3.710
|
|---|
| 1721 |
|
|---|
| 1722 |
|
|---|
| 1723 |
|
|---|
| 1724 | 45 contacts
|
|---|
| 1725 |
|
|---|
| 1726 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 1727 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2CPE--
|
|---|
| 1728 | > WRM-16.hbonds.txt
|
|---|
| 1729 |
|
|---|
| 1730 |
|
|---|
| 1731 | Finding intermodel H-bonds
|
|---|
| 1732 | Finding intramodel H-bonds
|
|---|
| 1733 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 1734 | Models used:
|
|---|
| 1735 | 1 2CPE.pdbqt
|
|---|
| 1736 | 2.1 2CPE--WRM-16.result.pdbqt
|
|---|
| 1737 |
|
|---|
| 1738 | 1 H-bonds
|
|---|
| 1739 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 1740 | 2CPE.pdbqt #1/A LEU 374 N 2CPE--WRM-16.result.pdbqt #2.1/? UNL 1 O 2CPE.pdbqt #1/A LEU 374 H 3.030 2.126
|
|---|
| 1741 |
|
|---|
| 1742 |
|
|---|
| 1743 |
|
|---|
| 1744 | 1 hydrogen bonds found
|
|---|
| 1745 |
|
|---|
| 1746 | > select :UNL
|
|---|
| 1747 |
|
|---|
| 1748 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 1749 |
|
|---|
| 1750 | > label sel text "Ligand "
|
|---|
| 1751 |
|
|---|
| 1752 | > label height 1
|
|---|
| 1753 |
|
|---|
| 1754 | > ~select
|
|---|
| 1755 |
|
|---|
| 1756 | Nothing selected
|
|---|
| 1757 |
|
|---|
| 1758 | > 2dlabels text "Binding Energy: -6.4 kcal/mol" color red size 18 xpos .03
|
|---|
| 1759 | > ypos .95
|
|---|
| 1760 |
|
|---|
| 1761 | > 2dlabels text "2CPE WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 1762 |
|
|---|
| 1763 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2CPE--
|
|---|
| 1764 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 1765 | > true
|
|---|
| 1766 |
|
|---|
| 1767 | > select :UNL
|
|---|
| 1768 |
|
|---|
| 1769 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 1770 |
|
|---|
| 1771 | > view sel
|
|---|
| 1772 |
|
|---|
| 1773 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2CPE--
|
|---|
| 1774 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 1775 | > true
|
|---|
| 1776 |
|
|---|
| 1777 | > close
|
|---|
| 1778 |
|
|---|
| 1779 | > wait 5
|
|---|
| 1780 |
|
|---|
| 1781 | > set bgColor white
|
|---|
| 1782 |
|
|---|
| 1783 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1XQZ.pdbqt
|
|---|
| 1784 |
|
|---|
| 1785 | Chain information for 1XQZ.pdbqt #1
|
|---|
| 1786 | ---
|
|---|
| 1787 | Chain | Description
|
|---|
| 1788 | A | No description available
|
|---|
| 1789 |
|
|---|
| 1790 | Opened 1XQZ.pdbqt containing 1 structures (4460 atoms, 4520 bonds)
|
|---|
| 1791 |
|
|---|
| 1792 | > wait 5
|
|---|
| 1793 |
|
|---|
| 1794 | > hide surfaces
|
|---|
| 1795 |
|
|---|
| 1796 | > hide atoms
|
|---|
| 1797 |
|
|---|
| 1798 | > show cartoons
|
|---|
| 1799 |
|
|---|
| 1800 | > wait 5
|
|---|
| 1801 |
|
|---|
| 1802 | > addh
|
|---|
| 1803 |
|
|---|
| 1804 | Summary of feedback from adding hydrogens to 1XQZ.pdbqt #1
|
|---|
| 1805 | ---
|
|---|
| 1806 | notes | No usable SEQRES records for 1XQZ.pdbqt (#1) chain A; guessing termini
|
|---|
| 1807 | instead
|
|---|
| 1808 | Chain-initial residues that are actual N termini: /A GLU 32
|
|---|
| 1809 | Chain-initial residues that are not actual N termini:
|
|---|
| 1810 | Chain-final residues that are actual C termini: /A SER 308
|
|---|
| 1811 | Chain-final residues that are not actual C termini:
|
|---|
| 1812 | 219 hydrogen bonds
|
|---|
| 1813 | 5 hydrogens added
|
|---|
| 1814 |
|
|---|
| 1815 |
|
|---|
| 1816 | > wait 5
|
|---|
| 1817 |
|
|---|
| 1818 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1XQZ--
|
|---|
| 1819 | > WRM-16.result.pdbqt
|
|---|
| 1820 |
|
|---|
| 1821 | Summary of feedback from opening
|
|---|
| 1822 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1XQZ--WRM-16.result.pdbqt
|
|---|
| 1823 | ---
|
|---|
| 1824 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 1825 | REMARK VINA RESULT: -9.1 0.000 0.000
|
|---|
| 1826 |
|
|---|
| 1827 | Ignored bad PDB record found on line 3
|
|---|
| 1828 | REMARK 5 active torsions:
|
|---|
| 1829 |
|
|---|
| 1830 | Ignored bad PDB record found on line 4
|
|---|
| 1831 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 1832 |
|
|---|
| 1833 | Ignored bad PDB record found on line 5
|
|---|
| 1834 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 1835 |
|
|---|
| 1836 | Ignored bad PDB record found on line 6
|
|---|
| 1837 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 1838 |
|
|---|
| 1839 | 184 messages similar to the above omitted
|
|---|
| 1840 |
|
|---|
| 1841 | Opened 1XQZ--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 1842 | bonds)
|
|---|
| 1843 |
|
|---|
| 1844 | > wait 5
|
|---|
| 1845 |
|
|---|
| 1846 | > close #2.2-9
|
|---|
| 1847 |
|
|---|
| 1848 | > wait 5
|
|---|
| 1849 |
|
|---|
| 1850 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 1851 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1XQZ--
|
|---|
| 1852 | > WRM-16.contacts.txt
|
|---|
| 1853 |
|
|---|
| 1854 |
|
|---|
| 1855 | Allowed overlap: -0.4
|
|---|
| 1856 | H-bond overlap reduction: 0.4
|
|---|
| 1857 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 1858 | Detect intra-residue contacts: False
|
|---|
| 1859 | Detect intra-molecule contacts: True
|
|---|
| 1860 |
|
|---|
| 1861 | 84 contacts
|
|---|
| 1862 | atom1 atom2 overlap distance
|
|---|
| 1863 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 120 3HD1 0.680 2.080
|
|---|
| 1864 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 120 3HD1 0.609 2.151
|
|---|
| 1865 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 104 2HG1 0.394 2.366
|
|---|
| 1866 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 120 CD1 0.391 3.069
|
|---|
| 1867 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ASP 186 HN 0.374 2.386
|
|---|
| 1868 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ASP 186 HB1 0.366 2.514
|
|---|
| 1869 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 120 CD1 0.197 3.263
|
|---|
| 1870 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A PHE 49 CE1 0.188 3.392
|
|---|
| 1871 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A VAL 126 3HG1 0.163 2.597
|
|---|
| 1872 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 104 2HG1 0.161 2.599
|
|---|
| 1873 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ASP 186 N 0.156 3.229
|
|---|
| 1874 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LYS 67 HZ3 0.141 2.619
|
|---|
| 1875 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XQZ.pdbqt #1/A ARG 122 HG1 0.131 2.289
|
|---|
| 1876 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 185 3HD1 0.128 2.752
|
|---|
| 1877 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 104 CG1 0.076 3.384
|
|---|
| 1878 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 44 3HD1 0.076 2.684
|
|---|
| 1879 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A GLU 121 O 0.067 3.293
|
|---|
| 1880 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ASP 186 HN 0.067 2.693
|
|---|
| 1881 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 120 3HD1 0.066 2.694
|
|---|
| 1882 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XQZ.pdbqt #1/A LEU 174 1HD1 0.058 2.402
|
|---|
| 1883 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ASP 186 CB 0.050 3.530
|
|---|
| 1884 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A PHE 49 CZ 0.039 3.541
|
|---|
| 1885 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 120 2HD2 0.018 2.742
|
|---|
| 1886 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ASP 186 HN -0.011 2.771
|
|---|
| 1887 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ALA 65 CB -0.021 3.601
|
|---|
| 1888 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ASP 186 HA -0.021 2.781
|
|---|
| 1889 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 104 CG1 -0.024 3.484
|
|---|
| 1890 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 120 CD1 -0.026 3.486
|
|---|
| 1891 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 104 1HG2 -0.033 2.913
|
|---|
| 1892 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XQZ.pdbqt #1/A ILE 104 1HG2 -0.053 2.513
|
|---|
| 1893 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ASP 186 N -0.056 3.441
|
|---|
| 1894 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ASP 186 CA -0.060 3.520
|
|---|
| 1895 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A VAL 126 3HG1 -0.062 2.822
|
|---|
| 1896 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A PHE 49 CD1 -0.070 3.650
|
|---|
| 1897 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 120 CD2 -0.091 3.551
|
|---|
| 1898 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 185 HB -0.091 2.701
|
|---|
| 1899 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A VAL 126 CG1 -0.109 3.569
|
|---|
| 1900 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LYS 67 NZ -0.112 3.497
|
|---|
| 1901 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XQZ.pdbqt #1/A PHE 49 CE1 -0.120 3.280
|
|---|
| 1902 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ASP 186 CA -0.125 3.585
|
|---|
| 1903 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 185 HB -0.127 2.887
|
|---|
| 1904 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 174 1HD1 -0.155 3.035
|
|---|
| 1905 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 185 3HD1 -0.155 2.765
|
|---|
| 1906 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ASP 186 HA -0.161 2.921
|
|---|
| 1907 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A VAL 126 CG1 -0.171 3.631
|
|---|
| 1908 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 104 CD1 -0.174 3.634
|
|---|
| 1909 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 185 CG2 -0.176 3.636
|
|---|
| 1910 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XQZ.pdbqt #1/A ARG 122 CG -0.191 3.311
|
|---|
| 1911 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 185 CD1 -0.193 3.773
|
|---|
| 1912 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ALA 65 HB3 -0.203 3.083
|
|---|
| 1913 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A VAL 126 3HG1 -0.203 2.813
|
|---|
| 1914 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XQZ.pdbqt #1/A LEU 174 CD1 -0.209 3.369
|
|---|
| 1915 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 120 3HD1 -0.219 2.829
|
|---|
| 1916 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LYS 67 HD1 -0.229 2.989
|
|---|
| 1917 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 185 3HD1 -0.241 2.851
|
|---|
| 1918 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 185 CB -0.253 3.713
|
|---|
| 1919 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 185 HB -0.285 2.895
|
|---|
| 1920 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 185 CG2 -0.295 3.605
|
|---|
| 1921 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 185 2HG2 -0.296 2.906
|
|---|
| 1922 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1XQZ.pdbqt #1/A VAL 126 O -0.301 3.661
|
|---|
| 1923 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 185 CB -0.302 3.612
|
|---|
| 1924 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ASP 186 CG -0.304 3.884
|
|---|
| 1925 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 104 CG2 -0.306 3.886
|
|---|
| 1926 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XQZ.pdbqt #1/A VAL 52 1HG1 -0.309 2.769
|
|---|
| 1927 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ASP 186 N -0.313 3.698
|
|---|
| 1928 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 120 2HD1 -0.313 3.073
|
|---|
| 1929 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ARG 122 HD2 -0.324 3.084
|
|---|
| 1930 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A VAL 52 1HG1 -0.325 2.935
|
|---|
| 1931 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 44 CD1 -0.326 3.786
|
|---|
| 1932 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XQZ.pdbqt #1/A ILE 185 2HG2 -0.327 2.787
|
|---|
| 1933 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 174 1HD2 -0.328 3.208
|
|---|
| 1934 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 104 1HG2 -0.336 3.096
|
|---|
| 1935 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 185 CD1 -0.337 3.647
|
|---|
| 1936 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A PHE 49 CE2 -0.340 3.920
|
|---|
| 1937 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 185 CG2 -0.342 3.652
|
|---|
| 1938 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 120 2HD1 -0.346 3.106
|
|---|
| 1939 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A VAL 52 1HG2 -0.351 2.961
|
|---|
| 1940 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 120 CG -0.363 3.823
|
|---|
| 1941 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 185 1HG2 -0.366 3.126
|
|---|
| 1942 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XQZ.pdbqt #1/A ILE 185 CG2 -0.373 3.533
|
|---|
| 1943 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 120 CB -0.387 3.967
|
|---|
| 1944 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A LEU 120 HB2 -0.393 3.273
|
|---|
| 1945 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A ILE 104 CB -0.393 3.853
|
|---|
| 1946 | 1XQZ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XQZ.pdbqt #1/A VAL 126 CG2 -0.396 3.856
|
|---|
| 1947 |
|
|---|
| 1948 |
|
|---|
| 1949 |
|
|---|
| 1950 | 84 contacts
|
|---|
| 1951 |
|
|---|
| 1952 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 1953 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1XQZ--
|
|---|
| 1954 | > WRM-16.hbonds.txt
|
|---|
| 1955 |
|
|---|
| 1956 |
|
|---|
| 1957 | Finding intermodel H-bonds
|
|---|
| 1958 | Finding intramodel H-bonds
|
|---|
| 1959 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 1960 | Models used:
|
|---|
| 1961 | 1 1XQZ.pdbqt
|
|---|
| 1962 | 2.1 1XQZ--WRM-16.result.pdbqt
|
|---|
| 1963 |
|
|---|
| 1964 | 0 H-bonds
|
|---|
| 1965 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 1966 |
|
|---|
| 1967 |
|
|---|
| 1968 |
|
|---|
| 1969 | 0 hydrogen bonds found
|
|---|
| 1970 |
|
|---|
| 1971 | > select :UNL
|
|---|
| 1972 |
|
|---|
| 1973 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 1974 |
|
|---|
| 1975 | > label sel text "Ligand "
|
|---|
| 1976 |
|
|---|
| 1977 | > label height 1
|
|---|
| 1978 |
|
|---|
| 1979 | > ~select
|
|---|
| 1980 |
|
|---|
| 1981 | Nothing selected
|
|---|
| 1982 |
|
|---|
| 1983 | > 2dlabels text "Binding Energy: -9.1 kcal/mol" color red size 18 xpos .03
|
|---|
| 1984 | > ypos .95
|
|---|
| 1985 |
|
|---|
| 1986 | > 2dlabels text "1XQZ WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 1987 |
|
|---|
| 1988 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1XQZ--
|
|---|
| 1989 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 1990 | > true
|
|---|
| 1991 |
|
|---|
| 1992 | > select :UNL
|
|---|
| 1993 |
|
|---|
| 1994 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 1995 |
|
|---|
| 1996 | > view sel
|
|---|
| 1997 |
|
|---|
| 1998 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1XQZ--
|
|---|
| 1999 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 2000 | > true
|
|---|
| 2001 |
|
|---|
| 2002 | > close
|
|---|
| 2003 |
|
|---|
| 2004 | > wait 5
|
|---|
| 2005 |
|
|---|
| 2006 | > set bgColor white
|
|---|
| 2007 |
|
|---|
| 2008 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1Z00.pdbqt
|
|---|
| 2009 |
|
|---|
| 2010 | Chain information for 1Z00.pdbqt #1
|
|---|
| 2011 | ---
|
|---|
| 2012 | Chain | Description
|
|---|
| 2013 | A | No description available
|
|---|
| 2014 | B | No description available
|
|---|
| 2015 |
|
|---|
| 2016 | Opened 1Z00.pdbqt containing 1 structures (2620 atoms, 2640 bonds)
|
|---|
| 2017 |
|
|---|
| 2018 | > wait 5
|
|---|
| 2019 |
|
|---|
| 2020 | > hide surfaces
|
|---|
| 2021 |
|
|---|
| 2022 | > hide atoms
|
|---|
| 2023 |
|
|---|
| 2024 | > show cartoons
|
|---|
| 2025 |
|
|---|
| 2026 | > wait 5
|
|---|
| 2027 |
|
|---|
| 2028 | > addh
|
|---|
| 2029 |
|
|---|
| 2030 | Summary of feedback from adding hydrogens to 1Z00.pdbqt #1
|
|---|
| 2031 | ---
|
|---|
| 2032 | notes | No usable SEQRES records for 1Z00.pdbqt (#1) chain A; guessing termini
|
|---|
| 2033 | instead
|
|---|
| 2034 | No usable SEQRES records for 1Z00.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 2035 | Chain-initial residues that are actual N termini: /A MET 219, /B MET 822
|
|---|
| 2036 | Chain-initial residues that are not actual N termini:
|
|---|
| 2037 | Chain-final residues that are actual C termini: /A HIS 302, /B LYS 905
|
|---|
| 2038 | Chain-final residues that are not actual C termini:
|
|---|
| 2039 | 131 hydrogen bonds
|
|---|
| 2040 | 0 hydrogens added
|
|---|
| 2041 |
|
|---|
| 2042 |
|
|---|
| 2043 | > wait 5
|
|---|
| 2044 |
|
|---|
| 2045 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1Z00--
|
|---|
| 2046 | > WRM-16.result.pdbqt
|
|---|
| 2047 |
|
|---|
| 2048 | Summary of feedback from opening
|
|---|
| 2049 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1Z00--WRM-16.result.pdbqt
|
|---|
| 2050 | ---
|
|---|
| 2051 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 2052 | REMARK VINA RESULT: -6.8 0.000 0.000
|
|---|
| 2053 |
|
|---|
| 2054 | Ignored bad PDB record found on line 3
|
|---|
| 2055 | REMARK 5 active torsions:
|
|---|
| 2056 |
|
|---|
| 2057 | Ignored bad PDB record found on line 4
|
|---|
| 2058 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 2059 |
|
|---|
| 2060 | Ignored bad PDB record found on line 5
|
|---|
| 2061 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 2062 |
|
|---|
| 2063 | Ignored bad PDB record found on line 6
|
|---|
| 2064 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 2065 |
|
|---|
| 2066 | 184 messages similar to the above omitted
|
|---|
| 2067 |
|
|---|
| 2068 | Opened 1Z00--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 2069 | bonds)
|
|---|
| 2070 |
|
|---|
| 2071 | > wait 5
|
|---|
| 2072 |
|
|---|
| 2073 | > close #2.2-9
|
|---|
| 2074 |
|
|---|
| 2075 | > wait 5
|
|---|
| 2076 |
|
|---|
| 2077 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 2078 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1Z00--
|
|---|
| 2079 | > WRM-16.contacts.txt
|
|---|
| 2080 |
|
|---|
| 2081 |
|
|---|
| 2082 | Allowed overlap: -0.4
|
|---|
| 2083 | H-bond overlap reduction: 0.4
|
|---|
| 2084 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 2085 | Detect intra-residue contacts: False
|
|---|
| 2086 | Detect intra-molecule contacts: True
|
|---|
| 2087 |
|
|---|
| 2088 | 52 contacts
|
|---|
| 2089 | atom1 atom2 overlap distance
|
|---|
| 2090 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/B PRO 845 HB2 0.383 2.377
|
|---|
| 2091 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LEU 222 3HD2 0.372 2.388
|
|---|
| 2092 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/B PRO 845 CB 0.368 3.092
|
|---|
| 2093 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LEU 227 HA 0.193 2.687
|
|---|
| 2094 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ALA 220 O 0.163 3.197
|
|---|
| 2095 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ALA 220 HB3 0.104 2.656
|
|---|
| 2096 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/B GLN 885 HB3 0.064 2.696
|
|---|
| 2097 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LYS 226 CB 0.063 3.397
|
|---|
| 2098 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LEU 222 CD2 0.020 3.440
|
|---|
| 2099 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ALA 220 CB 0.011 3.449
|
|---|
| 2100 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LEU 227 CD1 -0.010 3.470
|
|---|
| 2101 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LEU 227 CA -0.022 3.602
|
|---|
| 2102 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ALA 220 CB -0.036 3.496
|
|---|
| 2103 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ALA 220 HA -0.039 2.649
|
|---|
| 2104 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LYS 226 HZ3 -0.040 2.800
|
|---|
| 2105 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LYS 226 HZ3 -0.042 2.802
|
|---|
| 2106 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ALA 220 HB3 -0.083 2.843
|
|---|
| 2107 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 O 1Z00.pdbqt #1/A ASP 230 HB2 -0.087 2.507
|
|---|
| 2108 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/B PRO 845 HB2 -0.092 2.852
|
|---|
| 2109 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LYS 226 HB2 -0.100 2.860
|
|---|
| 2110 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/B GLN 885 HB3 -0.122 2.882
|
|---|
| 2111 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LEU 227 3HD1 -0.124 2.884
|
|---|
| 2112 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ASP 230 OD2 -0.127 3.367
|
|---|
| 2113 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/B PRO 845 HB3 -0.147 2.907
|
|---|
| 2114 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 O 1Z00.pdbqt #1/A ASP 230 CB -0.189 3.349
|
|---|
| 2115 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/B PRO 845 O -0.208 3.568
|
|---|
| 2116 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/B PRO 845 CB -0.211 3.671
|
|---|
| 2117 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ALA 220 HA -0.218 2.828
|
|---|
| 2118 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/B GLN 885 CD -0.225 3.685
|
|---|
| 2119 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ALA 220 CB -0.228 3.688
|
|---|
| 2120 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ALA 220 HB1 -0.260 3.020
|
|---|
| 2121 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LYS 226 NZ -0.264 3.649
|
|---|
| 2122 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/B GLN 885 CB -0.269 3.729
|
|---|
| 2123 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 O 1Z00.pdbqt #1/B GLN 885 OE1 -0.287 3.227
|
|---|
| 2124 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LEU 227 CD1 -0.288 3.868
|
|---|
| 2125 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LYS 226 HB3 -0.291 3.051
|
|---|
| 2126 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1Z00.pdbqt #1/A LEU 222 CD2 -0.295 3.875
|
|---|
| 2127 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ALA 220 CB -0.302 3.762
|
|---|
| 2128 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A MET 219 O -0.310 3.400
|
|---|
| 2129 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ALA 220 HB3 -0.324 3.084
|
|---|
| 2130 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ALA 220 HA -0.326 3.086
|
|---|
| 2131 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 O 1Z00.pdbqt #1/A ASP 230 CG -0.329 3.489
|
|---|
| 2132 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LYS 226 NZ -0.336 3.721
|
|---|
| 2133 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LEU 227 N -0.340 3.845
|
|---|
| 2134 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ALA 220 CA -0.348 3.658
|
|---|
| 2135 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 O 1Z00.pdbqt #1/A ASP 230 HB3 -0.357 2.817
|
|---|
| 2136 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/B GLN 885 CB -0.359 3.819
|
|---|
| 2137 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/B PRO 845 CB -0.362 3.822
|
|---|
| 2138 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A LYS 226 CB -0.369 3.829
|
|---|
| 2139 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ASP 230 OD2 -0.371 3.461
|
|---|
| 2140 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 C 1Z00.pdbqt #1/A ASP 230 OD2 -0.380 3.470
|
|---|
| 2141 | 1Z00--WRM-16.result.pdbqt #2.1/? UNL 1 O 1Z00.pdbqt #1/A ASP 230 CB -0.386 3.506
|
|---|
| 2142 |
|
|---|
| 2143 |
|
|---|
| 2144 |
|
|---|
| 2145 | 52 contacts
|
|---|
| 2146 |
|
|---|
| 2147 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 2148 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1Z00--
|
|---|
| 2149 | > WRM-16.hbonds.txt
|
|---|
| 2150 |
|
|---|
| 2151 |
|
|---|
| 2152 | Finding intermodel H-bonds
|
|---|
| 2153 | Finding intramodel H-bonds
|
|---|
| 2154 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 2155 | Models used:
|
|---|
| 2156 | 1 1Z00.pdbqt
|
|---|
| 2157 | 2.1 1Z00--WRM-16.result.pdbqt
|
|---|
| 2158 |
|
|---|
| 2159 | 0 H-bonds
|
|---|
| 2160 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 2161 |
|
|---|
| 2162 |
|
|---|
| 2163 |
|
|---|
| 2164 | 0 hydrogen bonds found
|
|---|
| 2165 |
|
|---|
| 2166 | > select :UNL
|
|---|
| 2167 |
|
|---|
| 2168 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 2169 |
|
|---|
| 2170 | > label sel text "Ligand "
|
|---|
| 2171 |
|
|---|
| 2172 | > label height 1
|
|---|
| 2173 |
|
|---|
| 2174 | > ~select
|
|---|
| 2175 |
|
|---|
| 2176 | Nothing selected
|
|---|
| 2177 |
|
|---|
| 2178 | > 2dlabels text "Binding Energy: -6.8 kcal/mol" color red size 18 xpos .03
|
|---|
| 2179 | > ypos .95
|
|---|
| 2180 |
|
|---|
| 2181 | > 2dlabels text "1Z00 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 2182 |
|
|---|
| 2183 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1Z00--
|
|---|
| 2184 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 2185 | > true
|
|---|
| 2186 |
|
|---|
| 2187 | > select :UNL
|
|---|
| 2188 |
|
|---|
| 2189 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 2190 |
|
|---|
| 2191 | > view sel
|
|---|
| 2192 |
|
|---|
| 2193 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1Z00--
|
|---|
| 2194 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 2195 | > true
|
|---|
| 2196 |
|
|---|
| 2197 | > close
|
|---|
| 2198 |
|
|---|
| 2199 | > wait 5
|
|---|
| 2200 |
|
|---|
| 2201 | > set bgColor white
|
|---|
| 2202 |
|
|---|
| 2203 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/2N1I.pdbqt
|
|---|
| 2204 |
|
|---|
| 2205 | Chain information for 2N1I.pdbqt #1
|
|---|
| 2206 | ---
|
|---|
| 2207 | Chain | Description
|
|---|
| 2208 | A | No description available
|
|---|
| 2209 |
|
|---|
| 2210 | Opened 2N1I.pdbqt containing 1 structures (2650 atoms, 2682 bonds)
|
|---|
| 2211 |
|
|---|
| 2212 | > wait 5
|
|---|
| 2213 |
|
|---|
| 2214 | > hide surfaces
|
|---|
| 2215 |
|
|---|
| 2216 | > hide atoms
|
|---|
| 2217 |
|
|---|
| 2218 | > show cartoons
|
|---|
| 2219 |
|
|---|
| 2220 | > wait 5
|
|---|
| 2221 |
|
|---|
| 2222 | > addh
|
|---|
| 2223 |
|
|---|
| 2224 | Summary of feedback from adding hydrogens to 2N1I.pdbqt #1
|
|---|
| 2225 | ---
|
|---|
| 2226 | notes | No usable SEQRES records for 2N1I.pdbqt (#1) chain A; guessing termini
|
|---|
| 2227 | instead
|
|---|
| 2228 | Chain-initial residues that are actual N termini: /A GLY 51
|
|---|
| 2229 | Chain-initial residues that are not actual N termini:
|
|---|
| 2230 | Chain-final residues that are actual C termini: /A GLU 226
|
|---|
| 2231 | Chain-final residues that are not actual C termini:
|
|---|
| 2232 | 70 hydrogen bonds
|
|---|
| 2233 | 0 hydrogens added
|
|---|
| 2234 |
|
|---|
| 2235 |
|
|---|
| 2236 | > wait 5
|
|---|
| 2237 |
|
|---|
| 2238 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2N1I--
|
|---|
| 2239 | > WRM-16.result.pdbqt
|
|---|
| 2240 |
|
|---|
| 2241 | Summary of feedback from opening
|
|---|
| 2242 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2N1I--WRM-16.result.pdbqt
|
|---|
| 2243 | ---
|
|---|
| 2244 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 2245 | REMARK VINA RESULT: -6.7 0.000 0.000
|
|---|
| 2246 |
|
|---|
| 2247 | Ignored bad PDB record found on line 3
|
|---|
| 2248 | REMARK 5 active torsions:
|
|---|
| 2249 |
|
|---|
| 2250 | Ignored bad PDB record found on line 4
|
|---|
| 2251 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 2252 |
|
|---|
| 2253 | Ignored bad PDB record found on line 5
|
|---|
| 2254 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 2255 |
|
|---|
| 2256 | Ignored bad PDB record found on line 6
|
|---|
| 2257 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 2258 |
|
|---|
| 2259 | 184 messages similar to the above omitted
|
|---|
| 2260 |
|
|---|
| 2261 | Opened 2N1I--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 2262 | bonds)
|
|---|
| 2263 |
|
|---|
| 2264 | > wait 5
|
|---|
| 2265 |
|
|---|
| 2266 | > close #2.2-9
|
|---|
| 2267 |
|
|---|
| 2268 | > wait 5
|
|---|
| 2269 |
|
|---|
| 2270 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 2271 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2N1I--
|
|---|
| 2272 | > WRM-16.contacts.txt
|
|---|
| 2273 |
|
|---|
| 2274 |
|
|---|
| 2275 | Allowed overlap: -0.4
|
|---|
| 2276 | H-bond overlap reduction: 0.4
|
|---|
| 2277 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 2278 | Detect intra-residue contacts: False
|
|---|
| 2279 | Detect intra-molecule contacts: True
|
|---|
| 2280 |
|
|---|
| 2281 | 54 contacts
|
|---|
| 2282 | atom1 atom2 overlap distance
|
|---|
| 2283 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A ARG 109 H 0.318 2.562
|
|---|
| 2284 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A MET 104 HG2 0.108 2.652
|
|---|
| 2285 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A ASP 159 HB3 0.091 2.789
|
|---|
| 2286 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A VAL 158 3HG1 0.063 2.547
|
|---|
| 2287 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2N1I.pdbqt #1/A LYS 103 O 0.016 3.344
|
|---|
| 2288 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A MET 104 HG2 0.000 2.760
|
|---|
| 2289 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A VAL 158 3HG1 -0.025 2.635
|
|---|
| 2290 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A ARG 109 N -0.031 3.536
|
|---|
| 2291 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A VAL 158 HA -0.034 2.794
|
|---|
| 2292 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A VAL 158 3HG1 -0.037 2.797
|
|---|
| 2293 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2N1I.pdbqt #1/A ARG 102 NH2 -0.075 3.580
|
|---|
| 2294 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A GLU 108 CB -0.088 3.548
|
|---|
| 2295 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A ASP 159 H -0.095 2.975
|
|---|
| 2296 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A ARG 102 NH1 -0.100 3.605
|
|---|
| 2297 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A ASP 159 O -0.123 3.483
|
|---|
| 2298 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A ARG 102 2HH1 -0.129 3.009
|
|---|
| 2299 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A GLU 108 HB2 -0.146 2.756
|
|---|
| 2300 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A ASP 83 OD1 -0.153 3.513
|
|---|
| 2301 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A ASP 159 CB -0.155 3.735
|
|---|
| 2302 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A MET 104 HG2 -0.170 2.780
|
|---|
| 2303 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2N1I.pdbqt #1/A LYS 103 HE2 -0.171 3.051
|
|---|
| 2304 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A GLU 108 HB3 -0.175 2.935
|
|---|
| 2305 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A MET 104 CG -0.213 3.673
|
|---|
| 2306 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A VAL 158 CG1 -0.216 3.526
|
|---|
| 2307 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2N1I.pdbqt #1/A ARG 102 CZ -0.232 3.812
|
|---|
| 2308 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A GLU 108 HA -0.236 3.116
|
|---|
| 2309 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A MET 104 HG2 -0.246 3.006
|
|---|
| 2310 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A GLU 105 H -0.256 3.016
|
|---|
| 2311 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A ARG 102 NH1 -0.256 3.641
|
|---|
| 2312 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A ASP 159 N -0.266 3.771
|
|---|
| 2313 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 O 2N1I.pdbqt #1/A ASP 159 O -0.268 3.208
|
|---|
| 2314 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A ARG 109 O -0.271 3.631
|
|---|
| 2315 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A GLU 108 CA -0.275 3.855
|
|---|
| 2316 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A MET 104 HA -0.288 3.048
|
|---|
| 2317 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A CYS 157 O -0.304 3.544
|
|---|
| 2318 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A VAL 158 CG1 -0.306 3.616
|
|---|
| 2319 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A GLU 108 HB2 -0.307 3.187
|
|---|
| 2320 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 O 2N1I.pdbqt #1/A MET 104 SD -0.309 3.511
|
|---|
| 2321 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 O 2N1I.pdbqt #1/A ASP 159 H -0.310 2.370
|
|---|
| 2322 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A GLU 108 CB -0.311 3.891
|
|---|
| 2323 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2N1I.pdbqt #1/A MET 104 HA -0.317 3.197
|
|---|
| 2324 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A VAL 158 CG1 -0.327 3.787
|
|---|
| 2325 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2N1I.pdbqt #1/A LYS 103 CE -0.328 3.908
|
|---|
| 2326 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A MET 104 CG -0.330 3.790
|
|---|
| 2327 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A VAL 158 CA -0.338 3.798
|
|---|
| 2328 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A MET 104 HG2 -0.339 3.099
|
|---|
| 2329 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A ARG 109 NH1 -0.340 3.845
|
|---|
| 2330 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A MET 104 HG2 -0.369 2.979
|
|---|
| 2331 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A GLU 108 CB -0.369 3.679
|
|---|
| 2332 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 O 2N1I.pdbqt #1/A VAL 158 CG1 -0.385 3.545
|
|---|
| 2333 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 O 2N1I.pdbqt #1/A ASP 159 C -0.387 3.547
|
|---|
| 2334 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A MET 104 HA -0.391 3.001
|
|---|
| 2335 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 C 2N1I.pdbqt #1/A ASP 83 OD2 -0.395 3.635
|
|---|
| 2336 | 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 O 2N1I.pdbqt #1/A ARG 109 O -0.398 3.298
|
|---|
| 2337 |
|
|---|
| 2338 |
|
|---|
| 2339 |
|
|---|
| 2340 | 54 contacts
|
|---|
| 2341 |
|
|---|
| 2342 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 2343 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2N1I--
|
|---|
| 2344 | > WRM-16.hbonds.txt
|
|---|
| 2345 |
|
|---|
| 2346 |
|
|---|
| 2347 | Finding intermodel H-bonds
|
|---|
| 2348 | Finding intramodel H-bonds
|
|---|
| 2349 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 2350 | Models used:
|
|---|
| 2351 | 1 2N1I.pdbqt
|
|---|
| 2352 | 2.1 2N1I--WRM-16.result.pdbqt
|
|---|
| 2353 |
|
|---|
| 2354 | 1 H-bonds
|
|---|
| 2355 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 2356 | 2N1I.pdbqt #1/A ASP 159 N 2N1I--WRM-16.result.pdbqt #2.1/? UNL 1 O 2N1I.pdbqt #1/A ASP 159 H 3.116 2.370
|
|---|
| 2357 |
|
|---|
| 2358 |
|
|---|
| 2359 |
|
|---|
| 2360 | 1 hydrogen bonds found
|
|---|
| 2361 |
|
|---|
| 2362 | > select :UNL
|
|---|
| 2363 |
|
|---|
| 2364 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 2365 |
|
|---|
| 2366 | > label sel text "Ligand "
|
|---|
| 2367 |
|
|---|
| 2368 | > label height 1
|
|---|
| 2369 |
|
|---|
| 2370 | > ~select
|
|---|
| 2371 |
|
|---|
| 2372 | Nothing selected
|
|---|
| 2373 |
|
|---|
| 2374 | > 2dlabels text "Binding Energy: -6.7 kcal/mol" color red size 18 xpos .03
|
|---|
| 2375 | > ypos .95
|
|---|
| 2376 |
|
|---|
| 2377 | > 2dlabels text "2N1I WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 2378 |
|
|---|
| 2379 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2N1I--
|
|---|
| 2380 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 2381 | > true
|
|---|
| 2382 |
|
|---|
| 2383 | > select :UNL
|
|---|
| 2384 |
|
|---|
| 2385 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 2386 |
|
|---|
| 2387 | > view sel
|
|---|
| 2388 |
|
|---|
| 2389 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2N1I--
|
|---|
| 2390 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 2391 | > true
|
|---|
| 2392 |
|
|---|
| 2393 | > close
|
|---|
| 2394 |
|
|---|
| 2395 | > wait 5
|
|---|
| 2396 |
|
|---|
| 2397 | > set bgColor white
|
|---|
| 2398 |
|
|---|
| 2399 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1P4U.pdbqt
|
|---|
| 2400 |
|
|---|
| 2401 | Chain information for 1P4U.pdbqt #1
|
|---|
| 2402 | ---
|
|---|
| 2403 | Chain | Description
|
|---|
| 2404 | A | No description available
|
|---|
| 2405 | B | No description available
|
|---|
| 2406 |
|
|---|
| 2407 | Opened 1P4U.pdbqt containing 1 structures (2389 atoms, 2419 bonds)
|
|---|
| 2408 |
|
|---|
| 2409 | > wait 5
|
|---|
| 2410 |
|
|---|
| 2411 | > hide surfaces
|
|---|
| 2412 |
|
|---|
| 2413 | > hide atoms
|
|---|
| 2414 |
|
|---|
| 2415 | > show cartoons
|
|---|
| 2416 |
|
|---|
| 2417 | > wait 5
|
|---|
| 2418 |
|
|---|
| 2419 | > addh
|
|---|
| 2420 |
|
|---|
| 2421 | Summary of feedback from adding hydrogens to 1P4U.pdbqt #1
|
|---|
| 2422 | ---
|
|---|
| 2423 | notes | No usable SEQRES records for 1P4U.pdbqt (#1) chain A; guessing termini
|
|---|
| 2424 | instead
|
|---|
| 2425 | No usable SEQRES records for 1P4U.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 2426 | Chain-initial residues that are actual N termini: /A LEU 579, /B ASP -1
|
|---|
| 2427 | Chain-initial residues that are not actual N termini:
|
|---|
| 2428 | Chain-final residues that are actual C termini: /A LEU 723, /B ALA 6
|
|---|
| 2429 | Chain-final residues that are not actual C termini:
|
|---|
| 2430 | 95 hydrogen bonds
|
|---|
| 2431 | 1 hydrogens added
|
|---|
| 2432 |
|
|---|
| 2433 |
|
|---|
| 2434 | > wait 5
|
|---|
| 2435 |
|
|---|
| 2436 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1P4U--
|
|---|
| 2437 | > WRM-16.result.pdbqt
|
|---|
| 2438 |
|
|---|
| 2439 | Summary of feedback from opening
|
|---|
| 2440 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1P4U--WRM-16.result.pdbqt
|
|---|
| 2441 | ---
|
|---|
| 2442 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 2443 | REMARK VINA RESULT: -7.2 0.000 0.000
|
|---|
| 2444 |
|
|---|
| 2445 | Ignored bad PDB record found on line 3
|
|---|
| 2446 | REMARK 5 active torsions:
|
|---|
| 2447 |
|
|---|
| 2448 | Ignored bad PDB record found on line 4
|
|---|
| 2449 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 2450 |
|
|---|
| 2451 | Ignored bad PDB record found on line 5
|
|---|
| 2452 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 2453 |
|
|---|
| 2454 | Ignored bad PDB record found on line 6
|
|---|
| 2455 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 2456 |
|
|---|
| 2457 | 184 messages similar to the above omitted
|
|---|
| 2458 |
|
|---|
| 2459 | Opened 1P4U--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 2460 | bonds)
|
|---|
| 2461 |
|
|---|
| 2462 | > wait 5
|
|---|
| 2463 |
|
|---|
| 2464 | > close #2.2-9
|
|---|
| 2465 |
|
|---|
| 2466 | > wait 5
|
|---|
| 2467 |
|
|---|
| 2468 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 2469 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1P4U--
|
|---|
| 2470 | > WRM-16.contacts.txt
|
|---|
| 2471 |
|
|---|
| 2472 |
|
|---|
| 2473 | Allowed overlap: -0.4
|
|---|
| 2474 | H-bond overlap reduction: 0.4
|
|---|
| 2475 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 2476 | Detect intra-residue contacts: False
|
|---|
| 2477 | Detect intra-molecule contacts: True
|
|---|
| 2478 |
|
|---|
| 2479 | 55 contacts
|
|---|
| 2480 | atom1 atom2 overlap distance
|
|---|
| 2481 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A THR 677 2HG2 0.351 2.409
|
|---|
| 2482 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 O 1P4U.pdbqt #1/A PRO 593 HA 0.208 2.212
|
|---|
| 2483 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 O 1P4U.pdbqt #1/A ALA 614 HA 0.167 2.253
|
|---|
| 2484 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A PHE 613 O 0.103 3.257
|
|---|
| 2485 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 O 1P4U.pdbqt #1/A ILE 591 HB 0.100 2.320
|
|---|
| 2486 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A VAL 628 3HG2 0.090 2.790
|
|---|
| 2487 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A LEU 588 1HD1 0.056 2.704
|
|---|
| 2488 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A PRO 593 HA 0.043 2.567
|
|---|
| 2489 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A THR 677 CG2 0.014 3.446
|
|---|
| 2490 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A LEU 588 1HD2 -0.042 2.652
|
|---|
| 2491 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A VAL 628 2HG1 -0.044 2.804
|
|---|
| 2492 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 O 1P4U.pdbqt #1/A VAL 628 3HG2 -0.081 2.501
|
|---|
| 2493 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A VAL 628 CG2 -0.090 3.670
|
|---|
| 2494 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A PHE 613 N -0.098 3.603
|
|---|
| 2495 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A SER 594 OG -0.119 3.499
|
|---|
| 2496 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A HIS 612 HD1 -0.120 2.730
|
|---|
| 2497 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A HIS 612 HB1 -0.124 3.004
|
|---|
| 2498 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A LEU 588 1HD2 -0.157 2.917
|
|---|
| 2499 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 O 1P4U.pdbqt #1/A PRO 593 CA -0.173 3.293
|
|---|
| 2500 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A HIS 612 HB1 -0.186 2.796
|
|---|
| 2501 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 O 1P4U.pdbqt #1/A ALA 614 CA -0.187 3.307
|
|---|
| 2502 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A HIS 612 HD1 -0.198 2.808
|
|---|
| 2503 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A HIS 612 ND1 -0.204 3.439
|
|---|
| 2504 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 O 1P4U.pdbqt #1/A VAL 628 CG2 -0.210 3.370
|
|---|
| 2505 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 O 1P4U.pdbqt #1/A VAL 628 3HG2 -0.214 2.674
|
|---|
| 2506 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 O 1P4U.pdbqt #1/A ILE 591 CB -0.242 3.362
|
|---|
| 2507 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 O 1P4U.pdbqt #1/A PHE 613 O -0.248 3.148
|
|---|
| 2508 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A ALA 596 O -0.255 3.615
|
|---|
| 2509 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A LEU 588 CD2 -0.257 3.717
|
|---|
| 2510 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A HIS 612 HD1 -0.261 3.021
|
|---|
| 2511 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A LEU 588 HG -0.270 3.030
|
|---|
| 2512 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A LEU 588 1HD2 -0.273 3.033
|
|---|
| 2513 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A HIS 612 ND1 -0.277 3.782
|
|---|
| 2514 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 O 1P4U.pdbqt #1/A LYS 592 O -0.287 3.187
|
|---|
| 2515 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A HIS 612 CB -0.297 3.877
|
|---|
| 2516 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A HIS 612 CE1 -0.299 3.879
|
|---|
| 2517 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A LEU 588 CD1 -0.303 3.763
|
|---|
| 2518 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A VAL 628 3HG2 -0.306 2.916
|
|---|
| 2519 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A LEU 588 1HD1 -0.312 2.922
|
|---|
| 2520 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A SER 594 HN -0.324 3.204
|
|---|
| 2521 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1P4U.pdbqt #1/A LEU 588 1HD2 -0.333 3.213
|
|---|
| 2522 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A PRO 593 CA -0.342 3.652
|
|---|
| 2523 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A PHE 613 HN -0.343 3.223
|
|---|
| 2524 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 O 1P4U.pdbqt #1/A SER 594 HN -0.343 2.403
|
|---|
| 2525 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A HIS 612 ND1 -0.350 3.735
|
|---|
| 2526 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A HIS 612 HB1 -0.352 2.962
|
|---|
| 2527 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 O 1P4U.pdbqt #1/A ILE 591 CG2 -0.367 3.527
|
|---|
| 2528 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A PRO 593 HA -0.370 2.980
|
|---|
| 2529 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A HIS 612 CA -0.376 3.956
|
|---|
| 2530 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A LEU 588 1HD1 -0.379 3.139
|
|---|
| 2531 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A HIS 612 ND1 -0.389 3.624
|
|---|
| 2532 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A HIS 612 C -0.391 3.971
|
|---|
| 2533 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A LEU 588 CG -0.391 3.851
|
|---|
| 2534 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A LEU 588 CD2 -0.395 3.705
|
|---|
| 2535 | 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 C 1P4U.pdbqt #1/A PRO 593 HB2 -0.395 3.005
|
|---|
| 2536 |
|
|---|
| 2537 |
|
|---|
| 2538 |
|
|---|
| 2539 | 55 contacts
|
|---|
| 2540 |
|
|---|
| 2541 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 2542 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1P4U--
|
|---|
| 2543 | > WRM-16.hbonds.txt
|
|---|
| 2544 |
|
|---|
| 2545 |
|
|---|
| 2546 | Finding intermodel H-bonds
|
|---|
| 2547 | Finding intramodel H-bonds
|
|---|
| 2548 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 2549 | Models used:
|
|---|
| 2550 | 1 1P4U.pdbqt
|
|---|
| 2551 | 2.1 1P4U--WRM-16.result.pdbqt
|
|---|
| 2552 |
|
|---|
| 2553 | 1 H-bonds
|
|---|
| 2554 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 2555 | 1P4U.pdbqt #1/A SER 594 N 1P4U--WRM-16.result.pdbqt #2.1/? UNL 1 O 1P4U.pdbqt #1/A SER 594 HN 3.335 2.403
|
|---|
| 2556 |
|
|---|
| 2557 |
|
|---|
| 2558 |
|
|---|
| 2559 | 1 hydrogen bonds found
|
|---|
| 2560 |
|
|---|
| 2561 | > select :UNL
|
|---|
| 2562 |
|
|---|
| 2563 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 2564 |
|
|---|
| 2565 | > label sel text "Ligand "
|
|---|
| 2566 |
|
|---|
| 2567 | > label height 1
|
|---|
| 2568 |
|
|---|
| 2569 | > ~select
|
|---|
| 2570 |
|
|---|
| 2571 | Nothing selected
|
|---|
| 2572 |
|
|---|
| 2573 | > 2dlabels text "Binding Energy: -7.2 kcal/mol" color red size 18 xpos .03
|
|---|
| 2574 | > ypos .95
|
|---|
| 2575 |
|
|---|
| 2576 | > 2dlabels text "1P4U WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 2577 |
|
|---|
| 2578 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1P4U--
|
|---|
| 2579 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 2580 | > true
|
|---|
| 2581 |
|
|---|
| 2582 | > select :UNL
|
|---|
| 2583 |
|
|---|
| 2584 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 2585 |
|
|---|
| 2586 | > view sel
|
|---|
| 2587 |
|
|---|
| 2588 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1P4U--
|
|---|
| 2589 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 2590 | > true
|
|---|
| 2591 |
|
|---|
| 2592 | > close
|
|---|
| 2593 |
|
|---|
| 2594 | > wait 5
|
|---|
| 2595 |
|
|---|
| 2596 | > set bgColor white
|
|---|
| 2597 |
|
|---|
| 2598 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/2KCX.pdbqt
|
|---|
| 2599 |
|
|---|
| 2600 | Chain information for 2KCX.pdbqt #1
|
|---|
| 2601 | ---
|
|---|
| 2602 | Chain | Description
|
|---|
| 2603 | A | No description available
|
|---|
| 2604 |
|
|---|
| 2605 | Opened 2KCX.pdbqt containing 1 structures (1066 atoms, 1073 bonds)
|
|---|
| 2606 |
|
|---|
| 2607 | > wait 5
|
|---|
| 2608 |
|
|---|
| 2609 | > hide surfaces
|
|---|
| 2610 |
|
|---|
| 2611 | > hide atoms
|
|---|
| 2612 |
|
|---|
| 2613 | > show cartoons
|
|---|
| 2614 |
|
|---|
| 2615 | > wait 5
|
|---|
| 2616 |
|
|---|
| 2617 | > addh
|
|---|
| 2618 |
|
|---|
| 2619 | Summary of feedback from adding hydrogens to 2KCX.pdbqt #1
|
|---|
| 2620 | ---
|
|---|
| 2621 | notes | No usable SEQRES records for 2KCX.pdbqt (#1) chain A; guessing termini
|
|---|
| 2622 | instead
|
|---|
| 2623 | Chain-initial residues that are actual N termini: /A SER 1
|
|---|
| 2624 | Chain-initial residues that are not actual N termini:
|
|---|
| 2625 | Chain-final residues that are actual C termini: /A LYS 74
|
|---|
| 2626 | Chain-final residues that are not actual C termini:
|
|---|
| 2627 | 56 hydrogen bonds
|
|---|
| 2628 | 10 hydrogens added
|
|---|
| 2629 |
|
|---|
| 2630 |
|
|---|
| 2631 | > wait 5
|
|---|
| 2632 |
|
|---|
| 2633 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2KCX--
|
|---|
| 2634 | > WRM-16.result.pdbqt
|
|---|
| 2635 |
|
|---|
| 2636 | Summary of feedback from opening
|
|---|
| 2637 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2KCX--WRM-16.result.pdbqt
|
|---|
| 2638 | ---
|
|---|
| 2639 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 2640 | REMARK VINA RESULT: -6.4 0.000 0.000
|
|---|
| 2641 |
|
|---|
| 2642 | Ignored bad PDB record found on line 3
|
|---|
| 2643 | REMARK 5 active torsions:
|
|---|
| 2644 |
|
|---|
| 2645 | Ignored bad PDB record found on line 4
|
|---|
| 2646 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 2647 |
|
|---|
| 2648 | Ignored bad PDB record found on line 5
|
|---|
| 2649 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 2650 |
|
|---|
| 2651 | Ignored bad PDB record found on line 6
|
|---|
| 2652 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 2653 |
|
|---|
| 2654 | 184 messages similar to the above omitted
|
|---|
| 2655 |
|
|---|
| 2656 | Opened 2KCX--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 2657 | bonds)
|
|---|
| 2658 |
|
|---|
| 2659 | > wait 5
|
|---|
| 2660 |
|
|---|
| 2661 | > close #2.2-9
|
|---|
| 2662 |
|
|---|
| 2663 | > wait 5
|
|---|
| 2664 |
|
|---|
| 2665 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 2666 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2KCX--
|
|---|
| 2667 | > WRM-16.contacts.txt
|
|---|
| 2668 |
|
|---|
| 2669 |
|
|---|
| 2670 | Allowed overlap: -0.4
|
|---|
| 2671 | H-bond overlap reduction: 0.4
|
|---|
| 2672 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 2673 | Detect intra-residue contacts: False
|
|---|
| 2674 | Detect intra-molecule contacts: True
|
|---|
| 2675 |
|
|---|
| 2676 | 41 contacts
|
|---|
| 2677 | atom1 atom2 overlap distance
|
|---|
| 2678 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A HIS 61 HE2 0.106 2.504
|
|---|
| 2679 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ARG 59 HG3 0.085 2.675
|
|---|
| 2680 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ARG 59 HG3 0.014 2.596
|
|---|
| 2681 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ARG 59 HG3 0.013 2.747
|
|---|
| 2682 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2KCX.pdbqt #1/A PRO 28 HD3 0.006 2.874
|
|---|
| 2683 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KCX.pdbqt #1/A HIS 61 HE2 -0.031 2.091
|
|---|
| 2684 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A TYR 47 CE2 -0.034 3.344
|
|---|
| 2685 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2KCX.pdbqt #1/A ALA 55 HB2 -0.081 2.961
|
|---|
| 2686 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ARG 59 HG3 -0.125 2.885
|
|---|
| 2687 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ALA 56 HA -0.126 2.886
|
|---|
| 2688 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2KCX.pdbqt #1/A ALA 55 CB -0.136 3.716
|
|---|
| 2689 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ALA 45 CB -0.155 3.615
|
|---|
| 2690 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A HIS 61 NE2 -0.167 3.402
|
|---|
| 2691 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ALA 56 CA -0.168 3.628
|
|---|
| 2692 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2KCX.pdbqt #1/A PRO 28 CD -0.169 3.749
|
|---|
| 2693 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ARG 59 CG -0.185 3.645
|
|---|
| 2694 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ARG 59 HG3 -0.195 2.955
|
|---|
| 2695 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2KCX.pdbqt #1/A PRO 28 CG -0.207 3.787
|
|---|
| 2696 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ALA 45 CB -0.220 3.800
|
|---|
| 2697 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A TYR 47 HA -0.222 2.982
|
|---|
| 2698 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A HIS 61 HE2 -0.225 3.105
|
|---|
| 2699 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ALA 55 CB -0.229 3.689
|
|---|
| 2700 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A TYR 47 HA -0.239 2.999
|
|---|
| 2701 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A HIS 61 HE2 -0.246 3.126
|
|---|
| 2702 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A TYR 47 CE2 -0.247 3.557
|
|---|
| 2703 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2KCX.pdbqt #1/A PRO 28 HG3 -0.250 3.130
|
|---|
| 2704 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ARG 59 CG -0.250 3.560
|
|---|
| 2705 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ALA 45 HB1 -0.258 3.018
|
|---|
| 2706 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ARG 59 CG -0.260 3.720
|
|---|
| 2707 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A HIS 61 NE2 -0.261 3.766
|
|---|
| 2708 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A GLU 52 OE1 -0.267 3.507
|
|---|
| 2709 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A THR 46 O -0.276 3.516
|
|---|
| 2710 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A TYR 47 CE2 -0.276 3.736
|
|---|
| 2711 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A TYR 47 CE2 -0.281 3.591
|
|---|
| 2712 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ALA 56 CB -0.323 3.783
|
|---|
| 2713 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A TYR 47 CD2 -0.340 3.800
|
|---|
| 2714 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ALA 56 N -0.347 3.732
|
|---|
| 2715 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ALA 56 CB -0.361 3.941
|
|---|
| 2716 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ALA 56 HB2 -0.382 3.142
|
|---|
| 2717 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KCX.pdbqt #1/A HIS 61 NE2 -0.387 3.072
|
|---|
| 2718 | 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KCX.pdbqt #1/A ALA 55 HB3 -0.388 3.148
|
|---|
| 2719 |
|
|---|
| 2720 |
|
|---|
| 2721 |
|
|---|
| 2722 | 41 contacts
|
|---|
| 2723 |
|
|---|
| 2724 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 2725 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2KCX--
|
|---|
| 2726 | > WRM-16.hbonds.txt
|
|---|
| 2727 |
|
|---|
| 2728 |
|
|---|
| 2729 | Finding intermodel H-bonds
|
|---|
| 2730 | Finding intramodel H-bonds
|
|---|
| 2731 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 2732 | Models used:
|
|---|
| 2733 | 1 2KCX.pdbqt
|
|---|
| 2734 | 2.1 2KCX--WRM-16.result.pdbqt
|
|---|
| 2735 |
|
|---|
| 2736 | 1 H-bonds
|
|---|
| 2737 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 2738 | 2KCX.pdbqt #1/A HIS 61 NE2 2KCX--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KCX.pdbqt #1/A HIS 61 HE2 3.072 2.091
|
|---|
| 2739 |
|
|---|
| 2740 |
|
|---|
| 2741 |
|
|---|
| 2742 | 1 hydrogen bonds found
|
|---|
| 2743 |
|
|---|
| 2744 | > select :UNL
|
|---|
| 2745 |
|
|---|
| 2746 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 2747 |
|
|---|
| 2748 | > label sel text "Ligand "
|
|---|
| 2749 |
|
|---|
| 2750 | > label height 1
|
|---|
| 2751 |
|
|---|
| 2752 | > ~select
|
|---|
| 2753 |
|
|---|
| 2754 | Nothing selected
|
|---|
| 2755 |
|
|---|
| 2756 | > 2dlabels text "Binding Energy: -6.4 kcal/mol" color red size 18 xpos .03
|
|---|
| 2757 | > ypos .95
|
|---|
| 2758 |
|
|---|
| 2759 | > 2dlabels text "2KCX WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 2760 |
|
|---|
| 2761 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2KCX--
|
|---|
| 2762 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 2763 | > true
|
|---|
| 2764 |
|
|---|
| 2765 | > select :UNL
|
|---|
| 2766 |
|
|---|
| 2767 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 2768 |
|
|---|
| 2769 | > view sel
|
|---|
| 2770 |
|
|---|
| 2771 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2KCX--
|
|---|
| 2772 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 2773 | > true
|
|---|
| 2774 |
|
|---|
| 2775 | > close
|
|---|
| 2776 |
|
|---|
| 2777 | > wait 5
|
|---|
| 2778 |
|
|---|
| 2779 | > set bgColor white
|
|---|
| 2780 |
|
|---|
| 2781 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1VR2.pdbqt
|
|---|
| 2782 |
|
|---|
| 2783 | Chain information for 1VR2.pdbqt #1
|
|---|
| 2784 | ---
|
|---|
| 2785 | Chain | Description
|
|---|
| 2786 | A | No description available
|
|---|
| 2787 |
|
|---|
| 2788 | Opened 1VR2.pdbqt containing 1 structures (4310 atoms, 4361 bonds)
|
|---|
| 2789 |
|
|---|
| 2790 | > wait 5
|
|---|
| 2791 |
|
|---|
| 2792 | > hide surfaces
|
|---|
| 2793 |
|
|---|
| 2794 | > hide atoms
|
|---|
| 2795 |
|
|---|
| 2796 | > show cartoons
|
|---|
| 2797 |
|
|---|
| 2798 | > wait 5
|
|---|
| 2799 |
|
|---|
| 2800 | > addh
|
|---|
| 2801 |
|
|---|
| 2802 | Summary of feedback from adding hydrogens to 1VR2.pdbqt #1
|
|---|
| 2803 | ---
|
|---|
| 2804 | warnings | Not adding hydrogens to /A LYS 838 CB because it is missing heavy-
|
|---|
| 2805 | atom bond partners
|
|---|
| 2806 | Not adding hydrogens to /A ARG 842 CB because it is missing heavy-atom bond
|
|---|
| 2807 | partners
|
|---|
| 2808 | Not adding hydrogens to /A PHE 845 CB because it is missing heavy-atom bond
|
|---|
| 2809 | partners
|
|---|
| 2810 | Not adding hydrogens to /A TYR 938 CB because it is missing heavy-atom bond
|
|---|
| 2811 | partners
|
|---|
| 2812 | Not adding hydrogens to /A LYS 939 CB because it is missing heavy-atom bond
|
|---|
| 2813 | partners
|
|---|
| 2814 | 6 messages similar to the above omitted
|
|---|
| 2815 | notes | No usable SEQRES records for 1VR2.pdbqt (#1) chain A; guessing termini
|
|---|
| 2816 | instead
|
|---|
| 2817 | Chain-initial residues that are actual N termini: /A LEU 820
|
|---|
| 2818 | Chain-initial residues that are not actual N termini: /A ASP 998, /A ASP 1064
|
|---|
| 2819 | Chain-final residues that are actual C termini: /A ALA 1168
|
|---|
| 2820 | Chain-final residues that are not actual C termini: /A LYS 939, /A PHE 1047
|
|---|
| 2821 | 222 hydrogen bonds
|
|---|
| 2822 | Adding 'H' to /A ASP 998
|
|---|
| 2823 | Adding 'H' to /A ASP 1064
|
|---|
| 2824 | /A LYS 939 is not terminus, removing H atom from 'C'
|
|---|
| 2825 | /A PHE 1047 is not terminus, removing H atom from 'C'
|
|---|
| 2826 | 2 hydrogens added
|
|---|
| 2827 |
|
|---|
| 2828 |
|
|---|
| 2829 | > wait 5
|
|---|
| 2830 |
|
|---|
| 2831 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1VR2--
|
|---|
| 2832 | > WRM-16.result.pdbqt
|
|---|
| 2833 |
|
|---|
| 2834 | Summary of feedback from opening
|
|---|
| 2835 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1VR2--WRM-16.result.pdbqt
|
|---|
| 2836 | ---
|
|---|
| 2837 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 2838 | REMARK VINA RESULT: -7.7 0.000 0.000
|
|---|
| 2839 |
|
|---|
| 2840 | Ignored bad PDB record found on line 3
|
|---|
| 2841 | REMARK 5 active torsions:
|
|---|
| 2842 |
|
|---|
| 2843 | Ignored bad PDB record found on line 4
|
|---|
| 2844 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 2845 |
|
|---|
| 2846 | Ignored bad PDB record found on line 5
|
|---|
| 2847 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 2848 |
|
|---|
| 2849 | Ignored bad PDB record found on line 6
|
|---|
| 2850 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 2851 |
|
|---|
| 2852 | 184 messages similar to the above omitted
|
|---|
| 2853 |
|
|---|
| 2854 | Opened 1VR2--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 2855 | bonds)
|
|---|
| 2856 |
|
|---|
| 2857 | > wait 5
|
|---|
| 2858 |
|
|---|
| 2859 | > close #2.2-9
|
|---|
| 2860 |
|
|---|
| 2861 | > wait 5
|
|---|
| 2862 |
|
|---|
| 2863 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 2864 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1VR2--
|
|---|
| 2865 | > WRM-16.contacts.txt
|
|---|
| 2866 |
|
|---|
| 2867 |
|
|---|
| 2868 | Allowed overlap: -0.4
|
|---|
| 2869 | H-bond overlap reduction: 0.4
|
|---|
| 2870 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 2871 | Detect intra-residue contacts: False
|
|---|
| 2872 | Detect intra-molecule contacts: True
|
|---|
| 2873 |
|
|---|
| 2874 | 47 contacts
|
|---|
| 2875 | atom1 atom2 overlap distance
|
|---|
| 2876 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1VR2.pdbqt #1/A GLY 846 HA1 0.221 2.659
|
|---|
| 2877 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1VR2.pdbqt #1/A LYS 868 HB1 0.195 2.685
|
|---|
| 2878 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A CYS 919 HN 0.178 2.582
|
|---|
| 2879 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A VAL 848 3HG2 0.116 2.764
|
|---|
| 2880 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A CYS 919 HN 0.070 2.690
|
|---|
| 2881 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1VR2.pdbqt #1/A GLN 847 HN 0.070 2.810
|
|---|
| 2882 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A VAL 848 CG2 0.032 3.548
|
|---|
| 2883 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 O 1VR2.pdbqt #1/A VAL 848 3HG2 0.032 2.428
|
|---|
| 2884 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A ALA 866 HB3 -0.025 2.785
|
|---|
| 2885 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1VR2.pdbqt #1/A LYS 868 CB -0.077 3.657
|
|---|
| 2886 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A ALA 866 CB -0.081 3.541
|
|---|
| 2887 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1VR2.pdbqt #1/A GLY 846 CA -0.093 3.673
|
|---|
| 2888 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A LEU 840 2HD1 -0.095 2.855
|
|---|
| 2889 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A ALA 866 CB -0.107 3.567
|
|---|
| 2890 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1VR2.pdbqt #1/A GLN 847 N -0.119 3.624
|
|---|
| 2891 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A LYS 868 HE1 -0.150 2.910
|
|---|
| 2892 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A PHE 918 CD1 -0.161 3.621
|
|---|
| 2893 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A PHE 918 HA -0.164 2.924
|
|---|
| 2894 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A CYS 919 N -0.209 3.594
|
|---|
| 2895 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A GLN 847 N -0.223 3.608
|
|---|
| 2896 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A LYS 868 HG2 -0.224 2.984
|
|---|
| 2897 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A CYS 919 N -0.239 3.624
|
|---|
| 2898 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 O 1VR2.pdbqt #1/A LEU 840 O -0.244 3.184
|
|---|
| 2899 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 O 1VR2.pdbqt #1/A VAL 848 2HG1 -0.254 2.714
|
|---|
| 2900 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A CYS 919 O -0.260 3.500
|
|---|
| 2901 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A VAL 848 CG2 -0.269 3.729
|
|---|
| 2902 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A VAL 848 CG2 -0.280 3.740
|
|---|
| 2903 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A VAL 848 3HG2 -0.284 2.894
|
|---|
| 2904 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A LYS 868 CE -0.291 3.751
|
|---|
| 2905 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A VAL 848 2HG1 -0.295 2.905
|
|---|
| 2906 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A LYS 868 CG -0.303 3.763
|
|---|
| 2907 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A LEU 840 2HD1 -0.308 3.068
|
|---|
| 2908 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A LEU 840 2HD1 -0.310 3.070
|
|---|
| 2909 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 O 1VR2.pdbqt #1/A VAL 848 CG2 -0.320 3.480
|
|---|
| 2910 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A LEU 840 HB2 -0.324 2.934
|
|---|
| 2911 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A PHE 918 CE1 -0.326 3.786
|
|---|
| 2912 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A LYS 868 HE1 -0.332 3.092
|
|---|
| 2913 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A VAL 848 CG2 -0.343 3.803
|
|---|
| 2914 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A VAL 848 CG2 -0.351 3.811
|
|---|
| 2915 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A VAL 848 3HG2 -0.354 2.964
|
|---|
| 2916 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A VAL 848 1HG2 -0.357 3.117
|
|---|
| 2917 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A VAL 848 1HG2 -0.371 3.131
|
|---|
| 2918 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A ALA 866 HB1 -0.375 3.135
|
|---|
| 2919 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A VAL 848 2HG2 -0.383 3.143
|
|---|
| 2920 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A LEU 840 HB2 -0.387 2.997
|
|---|
| 2921 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A LYS 868 CD -0.393 3.853
|
|---|
| 2922 | 1VR2--WRM-16.result.pdbqt #2.1/? UNL 1 C 1VR2.pdbqt #1/A LEU 840 HB2 -0.399 3.159
|
|---|
| 2923 |
|
|---|
| 2924 |
|
|---|
| 2925 |
|
|---|
| 2926 | 47 contacts
|
|---|
| 2927 |
|
|---|
| 2928 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 2929 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1VR2--
|
|---|
| 2930 | > WRM-16.hbonds.txt
|
|---|
| 2931 |
|
|---|
| 2932 |
|
|---|
| 2933 | Finding intermodel H-bonds
|
|---|
| 2934 | Finding intramodel H-bonds
|
|---|
| 2935 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 2936 | Models used:
|
|---|
| 2937 | 1 1VR2.pdbqt
|
|---|
| 2938 | 2.1 1VR2--WRM-16.result.pdbqt
|
|---|
| 2939 |
|
|---|
| 2940 | 0 H-bonds
|
|---|
| 2941 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 2942 |
|
|---|
| 2943 |
|
|---|
| 2944 |
|
|---|
| 2945 | 0 hydrogen bonds found
|
|---|
| 2946 |
|
|---|
| 2947 | > select :UNL
|
|---|
| 2948 |
|
|---|
| 2949 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 2950 |
|
|---|
| 2951 | > label sel text "Ligand "
|
|---|
| 2952 |
|
|---|
| 2953 | > label height 1
|
|---|
| 2954 |
|
|---|
| 2955 | > ~select
|
|---|
| 2956 |
|
|---|
| 2957 | Nothing selected
|
|---|
| 2958 |
|
|---|
| 2959 | > 2dlabels text "Binding Energy: -7.7 kcal/mol" color red size 18 xpos .03
|
|---|
| 2960 | > ypos .95
|
|---|
| 2961 |
|
|---|
| 2962 | > 2dlabels text "1VR2 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 2963 |
|
|---|
| 2964 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1VR2--
|
|---|
| 2965 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 2966 | > true
|
|---|
| 2967 |
|
|---|
| 2968 | > select :UNL
|
|---|
| 2969 |
|
|---|
| 2970 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 2971 |
|
|---|
| 2972 | > view sel
|
|---|
| 2973 |
|
|---|
| 2974 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1VR2--
|
|---|
| 2975 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 2976 | > true
|
|---|
| 2977 |
|
|---|
| 2978 | > close
|
|---|
| 2979 |
|
|---|
| 2980 | > wait 5
|
|---|
| 2981 |
|
|---|
| 2982 | > set bgColor white
|
|---|
| 2983 |
|
|---|
| 2984 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/5AX3.pdbqt
|
|---|
| 2985 |
|
|---|
| 2986 | Chain information for 5AX3.pdbqt #1
|
|---|
| 2987 | ---
|
|---|
| 2988 | Chain | Description
|
|---|
| 2989 | A | No description available
|
|---|
| 2990 | B | No description available
|
|---|
| 2991 |
|
|---|
| 2992 | Opened 5AX3.pdbqt containing 1 structures (5669 atoms, 5733 bonds)
|
|---|
| 2993 |
|
|---|
| 2994 | > wait 5
|
|---|
| 2995 |
|
|---|
| 2996 | > hide surfaces
|
|---|
| 2997 |
|
|---|
| 2998 | > hide atoms
|
|---|
| 2999 |
|
|---|
| 3000 | > show cartoons
|
|---|
| 3001 |
|
|---|
| 3002 | > wait 5
|
|---|
| 3003 |
|
|---|
| 3004 | > addh
|
|---|
| 3005 |
|
|---|
| 3006 | Summary of feedback from adding hydrogens to 5AX3.pdbqt #1
|
|---|
| 3007 | ---
|
|---|
| 3008 | notes | No usable SEQRES records for 5AX3.pdbqt (#1) chain A; guessing termini
|
|---|
| 3009 | instead
|
|---|
| 3010 | No usable SEQRES records for 5AX3.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 3011 | Chain-initial residues that are actual N termini: /A GLY 1, /B LEU 349
|
|---|
| 3012 | Chain-initial residues that are not actual N termini: /A TYR 27, /A PHE 174,
|
|---|
| 3013 | /A THR 181, /A GLY 194, /A LEU 248
|
|---|
| 3014 | Chain-final residues that are actual C termini: /A TYR 348, /B GLU 360
|
|---|
| 3015 | Chain-final residues that are not actual C termini: /A GLU 24, /A ALA 165, /A
|
|---|
| 3016 | VAL 179, /A LEU 191, /A ASP 241
|
|---|
| 3017 | 195 hydrogen bonds
|
|---|
| 3018 | Adding 'H' to /A TYR 27
|
|---|
| 3019 | Adding 'H' to /A PHE 174
|
|---|
| 3020 | Adding 'H' to /A THR 181
|
|---|
| 3021 | Adding 'H' to /A GLY 194
|
|---|
| 3022 | Adding 'H' to /A LEU 248
|
|---|
| 3023 | /A GLU 24 is not terminus, removing H atom from 'C'
|
|---|
| 3024 | /A ALA 165 is not terminus, removing H atom from 'C'
|
|---|
| 3025 | /A VAL 179 is not terminus, removing H atom from 'C'
|
|---|
| 3026 | /A LEU 191 is not terminus, removing H atom from 'C'
|
|---|
| 3027 | /A ASP 241 is not terminus, removing H atom from 'C'
|
|---|
| 3028 | -9 hydrogens added
|
|---|
| 3029 |
|
|---|
| 3030 |
|
|---|
| 3031 | > wait 5
|
|---|
| 3032 |
|
|---|
| 3033 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/5AX3--
|
|---|
| 3034 | > WRM-16.result.pdbqt
|
|---|
| 3035 |
|
|---|
| 3036 | Summary of feedback from opening
|
|---|
| 3037 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/5AX3--WRM-16.result.pdbqt
|
|---|
| 3038 | ---
|
|---|
| 3039 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 3040 | REMARK VINA RESULT: -7.2 0.000 0.000
|
|---|
| 3041 |
|
|---|
| 3042 | Ignored bad PDB record found on line 3
|
|---|
| 3043 | REMARK 5 active torsions:
|
|---|
| 3044 |
|
|---|
| 3045 | Ignored bad PDB record found on line 4
|
|---|
| 3046 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 3047 |
|
|---|
| 3048 | Ignored bad PDB record found on line 5
|
|---|
| 3049 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 3050 |
|
|---|
| 3051 | Ignored bad PDB record found on line 6
|
|---|
| 3052 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 3053 |
|
|---|
| 3054 | 184 messages similar to the above omitted
|
|---|
| 3055 |
|
|---|
| 3056 | Opened 5AX3--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 3057 | bonds)
|
|---|
| 3058 |
|
|---|
| 3059 | > wait 5
|
|---|
| 3060 |
|
|---|
| 3061 | > close #2.2-9
|
|---|
| 3062 |
|
|---|
| 3063 | > wait 5
|
|---|
| 3064 |
|
|---|
| 3065 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 3066 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5AX3--
|
|---|
| 3067 | > WRM-16.contacts.txt
|
|---|
| 3068 |
|
|---|
| 3069 |
|
|---|
| 3070 | Allowed overlap: -0.4
|
|---|
| 3071 | H-bond overlap reduction: 0.4
|
|---|
| 3072 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 3073 | Detect intra-residue contacts: False
|
|---|
| 3074 | Detect intra-molecule contacts: True
|
|---|
| 3075 |
|
|---|
| 3076 | 52 contacts
|
|---|
| 3077 | atom1 atom2 overlap distance
|
|---|
| 3078 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A GLN 345 HG1 0.154 2.606
|
|---|
| 3079 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 HG2 0.099 2.661
|
|---|
| 3080 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 O 5AX3.pdbqt #1/A PRO 14 HD1 0.056 2.404
|
|---|
| 3081 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A ILE 81 CG2 0.037 3.543
|
|---|
| 3082 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A ILE 81 3HG2 0.002 2.878
|
|---|
| 3083 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 O 5AX3.pdbqt #1/A PRO 14 HD1 -0.003 2.423
|
|---|
| 3084 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 84 HG2 -0.004 2.764
|
|---|
| 3085 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 O 5AX3.pdbqt #1/A GLY 13 HA1 -0.068 2.488
|
|---|
| 3086 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 HG2 -0.084 2.844
|
|---|
| 3087 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 HB2 -0.109 2.719
|
|---|
| 3088 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A GLY 13 HA1 -0.127 3.007
|
|---|
| 3089 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 O 5AX3.pdbqt #1/A PRO 14 CD -0.127 3.247
|
|---|
| 3090 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A ARG 15 HE -0.129 2.889
|
|---|
| 3091 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A ARG 82 O -0.141 3.501
|
|---|
| 3092 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 HD2 -0.141 2.901
|
|---|
| 3093 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A ILE 81 2HG2 -0.151 3.031
|
|---|
| 3094 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A GLN 345 HG1 -0.154 2.914
|
|---|
| 3095 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 HG2 -0.158 2.768
|
|---|
| 3096 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 HG1 -0.158 2.768
|
|---|
| 3097 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 O 5AX3.pdbqt #1/A ARG 15 CB -0.174 3.294
|
|---|
| 3098 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 84 CG -0.181 3.641
|
|---|
| 3099 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 HB2 -0.184 2.794
|
|---|
| 3100 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A ASP 79 OD2 -0.194 3.434
|
|---|
| 3101 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 HB2 -0.210 2.970
|
|---|
| 3102 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 CB -0.218 3.528
|
|---|
| 3103 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 HG1 -0.235 2.845
|
|---|
| 3104 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A GLY 13 HA1 -0.241 3.121
|
|---|
| 3105 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 HG1 -0.249 2.859
|
|---|
| 3106 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A GLN 345 CG -0.250 3.710
|
|---|
| 3107 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A ARG 82 O -0.279 3.519
|
|---|
| 3108 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 O 5AX3.pdbqt #1/A GLY 13 CA -0.284 3.404
|
|---|
| 3109 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A GLY 347 HN -0.284 3.044
|
|---|
| 3110 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 HG2 -0.287 3.047
|
|---|
| 3111 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 O 5AX3.pdbqt #1/A ILE 81 CG2 -0.288 3.448
|
|---|
| 3112 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 O 5AX3.pdbqt #1/A ARG 15 HB1 -0.297 2.717
|
|---|
| 3113 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 O 5AX3.pdbqt #1/A PRO 14 CD -0.304 3.464
|
|---|
| 3114 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 CG -0.311 3.771
|
|---|
| 3115 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A ARG 15 HE -0.322 2.932
|
|---|
| 3116 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 CB -0.324 3.634
|
|---|
| 3117 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 O 5AX3.pdbqt #1/A ARG 15 HN -0.330 2.350
|
|---|
| 3118 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 CG -0.346 3.806
|
|---|
| 3119 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A GLY 347 HN -0.347 3.107
|
|---|
| 3120 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 CG -0.353 3.663
|
|---|
| 3121 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A GLY 347 N -0.365 3.750
|
|---|
| 3122 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 84 HG2 -0.368 3.128
|
|---|
| 3123 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 O 5AX3.pdbqt #1/A PRO 346 HB2 -0.371 2.831
|
|---|
| 3124 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 HG1 -0.379 2.989
|
|---|
| 3125 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 HG1 -0.386 2.996
|
|---|
| 3126 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 CG -0.388 3.698
|
|---|
| 3127 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 CG -0.391 3.851
|
|---|
| 3128 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 346 HD2 -0.396 3.006
|
|---|
| 3129 | 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 C 5AX3.pdbqt #1/A PRO 84 HA -0.399 3.159
|
|---|
| 3130 |
|
|---|
| 3131 |
|
|---|
| 3132 |
|
|---|
| 3133 | 52 contacts
|
|---|
| 3134 |
|
|---|
| 3135 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 3136 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5AX3--
|
|---|
| 3137 | > WRM-16.hbonds.txt
|
|---|
| 3138 |
|
|---|
| 3139 |
|
|---|
| 3140 | Finding intermodel H-bonds
|
|---|
| 3141 | Finding intramodel H-bonds
|
|---|
| 3142 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 3143 | Models used:
|
|---|
| 3144 | 1 5AX3.pdbqt
|
|---|
| 3145 | 2.1 5AX3--WRM-16.result.pdbqt
|
|---|
| 3146 |
|
|---|
| 3147 | 1 H-bonds
|
|---|
| 3148 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 3149 | 5AX3.pdbqt #1/A ARG 15 N 5AX3--WRM-16.result.pdbqt #2.1/? UNL 1 O 5AX3.pdbqt #1/A ARG 15 HN 3.304 2.350
|
|---|
| 3150 |
|
|---|
| 3151 |
|
|---|
| 3152 |
|
|---|
| 3153 | 1 hydrogen bonds found
|
|---|
| 3154 |
|
|---|
| 3155 | > select :UNL
|
|---|
| 3156 |
|
|---|
| 3157 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 3158 |
|
|---|
| 3159 | > label sel text "Ligand "
|
|---|
| 3160 |
|
|---|
| 3161 | > label height 1
|
|---|
| 3162 |
|
|---|
| 3163 | > ~select
|
|---|
| 3164 |
|
|---|
| 3165 | Nothing selected
|
|---|
| 3166 |
|
|---|
| 3167 | > 2dlabels text "Binding Energy: -7.2 kcal/mol" color red size 18 xpos .03
|
|---|
| 3168 | > ypos .95
|
|---|
| 3169 |
|
|---|
| 3170 | > 2dlabels text "5AX3 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 3171 |
|
|---|
| 3172 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5AX3--
|
|---|
| 3173 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 3174 | > true
|
|---|
| 3175 |
|
|---|
| 3176 | > select :UNL
|
|---|
| 3177 |
|
|---|
| 3178 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 3179 |
|
|---|
| 3180 | > view sel
|
|---|
| 3181 |
|
|---|
| 3182 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5AX3--
|
|---|
| 3183 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 3184 | > true
|
|---|
| 3185 |
|
|---|
| 3186 | > close
|
|---|
| 3187 |
|
|---|
| 3188 | > wait 5
|
|---|
| 3189 |
|
|---|
| 3190 | > set bgColor white
|
|---|
| 3191 |
|
|---|
| 3192 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/2KMU.pdbqt
|
|---|
| 3193 |
|
|---|
| 3194 | Chain information for 2KMU.pdbqt #1
|
|---|
| 3195 | ---
|
|---|
| 3196 | Chain | Description
|
|---|
| 3197 | A | No description available
|
|---|
| 3198 |
|
|---|
| 3199 | Opened 2KMU.pdbqt containing 1 structures (957 atoms, 963 bonds)
|
|---|
| 3200 |
|
|---|
| 3201 | > wait 5
|
|---|
| 3202 |
|
|---|
| 3203 | > hide surfaces
|
|---|
| 3204 |
|
|---|
| 3205 | > hide atoms
|
|---|
| 3206 |
|
|---|
| 3207 | > show cartoons
|
|---|
| 3208 |
|
|---|
| 3209 | > wait 5
|
|---|
| 3210 |
|
|---|
| 3211 | > addh
|
|---|
| 3212 |
|
|---|
| 3213 | Summary of feedback from adding hydrogens to 2KMU.pdbqt #1
|
|---|
| 3214 | ---
|
|---|
| 3215 | notes | No usable SEQRES records for 2KMU.pdbqt (#1) chain A; guessing termini
|
|---|
| 3216 | instead
|
|---|
| 3217 | Chain-initial residues that are actual N termini: /A GLY 1
|
|---|
| 3218 | Chain-initial residues that are not actual N termini:
|
|---|
| 3219 | Chain-final residues that are actual C termini: /A GLN 56
|
|---|
| 3220 | Chain-final residues that are not actual C termini:
|
|---|
| 3221 | 40 hydrogen bonds
|
|---|
| 3222 | 1 hydrogens added
|
|---|
| 3223 |
|
|---|
| 3224 |
|
|---|
| 3225 | > wait 5
|
|---|
| 3226 |
|
|---|
| 3227 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2KMU--
|
|---|
| 3228 | > WRM-16.result.pdbqt
|
|---|
| 3229 |
|
|---|
| 3230 | Summary of feedback from opening
|
|---|
| 3231 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2KMU--WRM-16.result.pdbqt
|
|---|
| 3232 | ---
|
|---|
| 3233 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 3234 | REMARK VINA RESULT: -6.8 0.000 0.000
|
|---|
| 3235 |
|
|---|
| 3236 | Ignored bad PDB record found on line 3
|
|---|
| 3237 | REMARK 5 active torsions:
|
|---|
| 3238 |
|
|---|
| 3239 | Ignored bad PDB record found on line 4
|
|---|
| 3240 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 3241 |
|
|---|
| 3242 | Ignored bad PDB record found on line 5
|
|---|
| 3243 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 3244 |
|
|---|
| 3245 | Ignored bad PDB record found on line 6
|
|---|
| 3246 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 3247 |
|
|---|
| 3248 | 184 messages similar to the above omitted
|
|---|
| 3249 |
|
|---|
| 3250 | Opened 2KMU--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 3251 | bonds)
|
|---|
| 3252 |
|
|---|
| 3253 | > wait 5
|
|---|
| 3254 |
|
|---|
| 3255 | > close #2.2-9
|
|---|
| 3256 |
|
|---|
| 3257 | > wait 5
|
|---|
| 3258 |
|
|---|
| 3259 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 3260 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2KMU--
|
|---|
| 3261 | > WRM-16.contacts.txt
|
|---|
| 3262 |
|
|---|
| 3263 |
|
|---|
| 3264 | Allowed overlap: -0.4
|
|---|
| 3265 | H-bond overlap reduction: 0.4
|
|---|
| 3266 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 3267 | Detect intra-residue contacts: False
|
|---|
| 3268 | Detect intra-molecule contacts: True
|
|---|
| 3269 |
|
|---|
| 3270 | 55 contacts
|
|---|
| 3271 | atom1 atom2 overlap distance
|
|---|
| 3272 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ALA 19 HB2 0.691 2.069
|
|---|
| 3273 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ALA 19 CB 0.326 3.134
|
|---|
| 3274 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ARG 24 1HH2 0.311 2.449
|
|---|
| 3275 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ARG 24 NH2 0.233 3.152
|
|---|
| 3276 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ALA 19 HB2 0.185 2.575
|
|---|
| 3277 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A TYR 44 HE2 0.153 2.727
|
|---|
| 3278 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ARG 24 1HH2 0.129 2.631
|
|---|
| 3279 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A TRP 16 HE3 0.035 2.575
|
|---|
| 3280 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A TRP 16 HZ3 0.021 2.589
|
|---|
| 3281 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A TYR 44 OH -0.037 3.147
|
|---|
| 3282 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KMU.pdbqt #1/A TRP 16 HA -0.042 2.502
|
|---|
| 3283 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A PRO 37 HD3 -0.069 2.829
|
|---|
| 3284 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A TYR 44 HH -0.072 2.682
|
|---|
| 3285 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A TYR 44 CE2 -0.105 3.685
|
|---|
| 3286 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A PRO 37 HD3 -0.109 2.869
|
|---|
| 3287 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KMU.pdbqt #1/A ARG 12 NH1 -0.111 2.796
|
|---|
| 3288 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ALA 19 CB -0.121 3.581
|
|---|
| 3289 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ARG 24 NE -0.127 3.512
|
|---|
| 3290 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ALA 36 HB1 -0.128 2.738
|
|---|
| 3291 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ARG 12 NH1 -0.135 3.370
|
|---|
| 3292 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ARG 24 HE -0.136 2.896
|
|---|
| 3293 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A THR 40 2HG2 -0.154 2.914
|
|---|
| 3294 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A PRO 37 CD -0.168 3.628
|
|---|
| 3295 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ARG 24 NH2 -0.173 3.558
|
|---|
| 3296 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A TRP 16 HZ3 -0.176 2.786
|
|---|
| 3297 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A PRO 37 CD -0.188 3.648
|
|---|
| 3298 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A TRP 16 HE3 -0.191 2.801
|
|---|
| 3299 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ARG 12 NH1 -0.202 3.587
|
|---|
| 3300 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A TRP 16 CE3 -0.202 3.512
|
|---|
| 3301 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ALA 19 CB -0.205 3.785
|
|---|
| 3302 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ARG 24 CZ -0.217 3.677
|
|---|
| 3303 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ALA 19 C -0.231 3.691
|
|---|
| 3304 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ALA 15 O -0.232 3.592
|
|---|
| 3305 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ALA 36 HB1 -0.241 3.121
|
|---|
| 3306 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A TRP 16 CZ3 -0.251 3.561
|
|---|
| 3307 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ALA 19 HB1 -0.264 3.144
|
|---|
| 3308 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A PRO 37 CD -0.289 3.749
|
|---|
| 3309 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A TRP 16 HZ3 -0.305 3.065
|
|---|
| 3310 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A THR 40 OG1 -0.306 3.566
|
|---|
| 3311 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A PRO 37 CD -0.310 3.770
|
|---|
| 3312 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KMU.pdbqt #1/A TRP 16 CA -0.310 3.470
|
|---|
| 3313 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A PRO 37 HD2 -0.313 3.073
|
|---|
| 3314 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A PHE 20 N -0.315 3.700
|
|---|
| 3315 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A PRO 37 CG -0.334 3.794
|
|---|
| 3316 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2KMU.pdbqt #1/A PRO 37 HG3 -0.336 3.216
|
|---|
| 3317 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KMU.pdbqt #1/A ALA 15 O -0.344 3.284
|
|---|
| 3318 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 O 2KMU.pdbqt #1/A ARG 12 2HH1 -0.344 2.404
|
|---|
| 3319 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ALA 19 C -0.359 3.819
|
|---|
| 3320 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A PHE 20 N -0.363 3.748
|
|---|
| 3321 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A PRO 37 CD -0.364 3.674
|
|---|
| 3322 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A TRP 16 CZ3 -0.366 3.676
|
|---|
| 3323 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ALA 36 CB -0.371 3.681
|
|---|
| 3324 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A TYR 44 OH -0.376 3.756
|
|---|
| 3325 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A ARG 12 1HH1 -0.384 3.144
|
|---|
| 3326 | 2KMU--WRM-16.result.pdbqt #2.1/? UNL 1 C 2KMU.pdbqt #1/A TRP 16 HZ3 -0.391 3.001
|
|---|
| 3327 |
|
|---|
| 3328 |
|
|---|
| 3329 |
|
|---|
| 3330 | 55 contacts
|
|---|
| 3331 |
|
|---|
| 3332 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 3333 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2KMU--
|
|---|
| 3334 | > WRM-16.hbonds.txt
|
|---|
| 3335 |
|
|---|
| 3336 |
|
|---|
| 3337 | Finding intermodel H-bonds
|
|---|
| 3338 | Finding intramodel H-bonds
|
|---|
| 3339 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 3340 | Models used:
|
|---|
| 3341 | 1 2KMU.pdbqt
|
|---|
| 3342 | 2.1 2KMU--WRM-16.result.pdbqt
|
|---|
| 3343 |
|
|---|
| 3344 | 0 H-bonds
|
|---|
| 3345 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 3346 |
|
|---|
| 3347 |
|
|---|
| 3348 |
|
|---|
| 3349 | 0 hydrogen bonds found
|
|---|
| 3350 |
|
|---|
| 3351 | > select :UNL
|
|---|
| 3352 |
|
|---|
| 3353 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 3354 |
|
|---|
| 3355 | > label sel text "Ligand "
|
|---|
| 3356 |
|
|---|
| 3357 | > label height 1
|
|---|
| 3358 |
|
|---|
| 3359 | > ~select
|
|---|
| 3360 |
|
|---|
| 3361 | Nothing selected
|
|---|
| 3362 |
|
|---|
| 3363 | > 2dlabels text "Binding Energy: -6.8 kcal/mol" color red size 18 xpos .03
|
|---|
| 3364 | > ypos .95
|
|---|
| 3365 |
|
|---|
| 3366 | > 2dlabels text "2KMU WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 3367 |
|
|---|
| 3368 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2KMU--
|
|---|
| 3369 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 3370 | > true
|
|---|
| 3371 |
|
|---|
| 3372 | > select :UNL
|
|---|
| 3373 |
|
|---|
| 3374 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 3375 |
|
|---|
| 3376 | > view sel
|
|---|
| 3377 |
|
|---|
| 3378 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2KMU--
|
|---|
| 3379 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 3380 | > true
|
|---|
| 3381 |
|
|---|
| 3382 | > close
|
|---|
| 3383 |
|
|---|
| 3384 | > wait 5
|
|---|
| 3385 |
|
|---|
| 3386 | > set bgColor white
|
|---|
| 3387 |
|
|---|
| 3388 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/2D68.pdbqt
|
|---|
| 3389 |
|
|---|
| 3390 | Chain information for 2D68.pdbqt #1
|
|---|
| 3391 | ---
|
|---|
| 3392 | Chain | Description
|
|---|
| 3393 | A | No description available
|
|---|
| 3394 | B | No description available
|
|---|
| 3395 |
|
|---|
| 3396 | Opened 2D68.pdbqt containing 1 structures (2419 atoms, 2436 bonds)
|
|---|
| 3397 |
|
|---|
| 3398 | > wait 5
|
|---|
| 3399 |
|
|---|
| 3400 | > hide surfaces
|
|---|
| 3401 |
|
|---|
| 3402 | > hide atoms
|
|---|
| 3403 |
|
|---|
| 3404 | > show cartoons
|
|---|
| 3405 |
|
|---|
| 3406 | > wait 5
|
|---|
| 3407 |
|
|---|
| 3408 | > addh
|
|---|
| 3409 |
|
|---|
| 3410 | Summary of feedback from adding hydrogens to 2D68.pdbqt #1
|
|---|
| 3411 | ---
|
|---|
| 3412 | warnings | Not adding hydrogens to /A LYS 69 CD because it is missing heavy-
|
|---|
| 3413 | atom bond partners
|
|---|
| 3414 | Not adding hydrogens to /B LYS 69 CG because it is missing heavy-atom bond
|
|---|
| 3415 | partners
|
|---|
| 3416 | notes | No usable SEQRES records for 2D68.pdbqt (#1) chain A; guessing termini
|
|---|
| 3417 | instead
|
|---|
| 3418 | No usable SEQRES records for 2D68.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 3419 | Chain-initial residues that are actual N termini: /A VAL 58, /B ASN 59
|
|---|
| 3420 | Chain-initial residues that are not actual N termini: /A LEU 104
|
|---|
| 3421 | Chain-final residues that are actual C termini: /A TRP 135, /B TRP 135
|
|---|
| 3422 | Chain-final residues that are not actual C termini: /A THR 100
|
|---|
| 3423 | 143 hydrogen bonds
|
|---|
| 3424 | Adding 'H' to /A LEU 104
|
|---|
| 3425 | /A THR 100 is not terminus, removing H atom from 'C'
|
|---|
| 3426 | -3 hydrogens added
|
|---|
| 3427 |
|
|---|
| 3428 |
|
|---|
| 3429 | > wait 5
|
|---|
| 3430 |
|
|---|
| 3431 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2D68--
|
|---|
| 3432 | > WRM-16.result.pdbqt
|
|---|
| 3433 |
|
|---|
| 3434 | Summary of feedback from opening
|
|---|
| 3435 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2D68--WRM-16.result.pdbqt
|
|---|
| 3436 | ---
|
|---|
| 3437 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 3438 | REMARK VINA RESULT: -6.5 0.000 0.000
|
|---|
| 3439 |
|
|---|
| 3440 | Ignored bad PDB record found on line 3
|
|---|
| 3441 | REMARK 5 active torsions:
|
|---|
| 3442 |
|
|---|
| 3443 | Ignored bad PDB record found on line 4
|
|---|
| 3444 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 3445 |
|
|---|
| 3446 | Ignored bad PDB record found on line 5
|
|---|
| 3447 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 3448 |
|
|---|
| 3449 | Ignored bad PDB record found on line 6
|
|---|
| 3450 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 3451 |
|
|---|
| 3452 | 184 messages similar to the above omitted
|
|---|
| 3453 |
|
|---|
| 3454 | Opened 2D68--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 3455 | bonds)
|
|---|
| 3456 |
|
|---|
| 3457 | > wait 5
|
|---|
| 3458 |
|
|---|
| 3459 | > close #2.2-9
|
|---|
| 3460 |
|
|---|
| 3461 | > wait 5
|
|---|
| 3462 |
|
|---|
| 3463 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 3464 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2D68--
|
|---|
| 3465 | > WRM-16.contacts.txt
|
|---|
| 3466 |
|
|---|
| 3467 |
|
|---|
| 3468 | Allowed overlap: -0.4
|
|---|
| 3469 | H-bond overlap reduction: 0.4
|
|---|
| 3470 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 3471 | Detect intra-residue contacts: False
|
|---|
| 3472 | Detect intra-molecule contacts: True
|
|---|
| 3473 |
|
|---|
| 3474 | 45 contacts
|
|---|
| 3475 | atom1 atom2 overlap distance
|
|---|
| 3476 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B LYS 64 HD2 0.473 2.407
|
|---|
| 3477 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B LYS 64 HD1 0.376 2.384
|
|---|
| 3478 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B SER 61 HB1 0.240 2.640
|
|---|
| 3479 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B SER 61 HA 0.211 2.669
|
|---|
| 3480 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B LYS 64 CD 0.179 3.281
|
|---|
| 3481 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B PHE 65 HD1 0.147 2.733
|
|---|
| 3482 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B LYS 64 CD 0.095 3.485
|
|---|
| 3483 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B LYS 64 HD1 0.057 2.703
|
|---|
| 3484 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 O 2D68.pdbqt #1/B PHE 65 HD1 0.023 2.437
|
|---|
| 3485 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 O 2D68.pdbqt #1/B PHE 65 HA 0.004 2.456
|
|---|
| 3486 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B SER 61 CB -0.002 3.582
|
|---|
| 3487 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 O 2D68.pdbqt #1/B PHE 65 HD1 -0.029 2.449
|
|---|
| 3488 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 O 2D68.pdbqt #1/B PHE 65 CD1 -0.031 3.151
|
|---|
| 3489 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 O 2D68.pdbqt #1/A PHE 85 HZ -0.041 2.461
|
|---|
| 3490 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B LYS 64 HB1 -0.069 2.829
|
|---|
| 3491 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/A PHE 84 CZ -0.108 3.568
|
|---|
| 3492 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/A GLY 124 O -0.108 3.468
|
|---|
| 3493 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2D68.pdbqt #1/A PHE 84 O -0.119 3.479
|
|---|
| 3494 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B SER 61 CA -0.139 3.719
|
|---|
| 3495 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B LYS 64 HB1 -0.157 2.917
|
|---|
| 3496 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/A PHE 84 O -0.164 3.404
|
|---|
| 3497 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 O 2D68.pdbqt #1/B PHE 65 CA -0.169 3.329
|
|---|
| 3498 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 O 2D68.pdbqt #1/A PHE 85 CZ -0.174 3.294
|
|---|
| 3499 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B PHE 65 CD1 -0.195 3.775
|
|---|
| 3500 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 O 2D68.pdbqt #1/A PHE 84 HE2 -0.224 2.684
|
|---|
| 3501 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/A PHE 84 CE2 -0.261 3.721
|
|---|
| 3502 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 O 2D68.pdbqt #1/B PHE 65 CD1 -0.269 3.429
|
|---|
| 3503 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/A PHE 84 CZ -0.272 3.582
|
|---|
| 3504 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B LYS 64 CD -0.275 3.735
|
|---|
| 3505 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B LYS 64 HB1 -0.282 2.892
|
|---|
| 3506 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B LYS 64 HB1 -0.283 3.043
|
|---|
| 3507 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B LYS 64 HB1 -0.310 3.070
|
|---|
| 3508 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2D68.pdbqt #1/A PHE 84 CE1 -0.322 3.902
|
|---|
| 3509 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/A GLY 124 O -0.324 3.414
|
|---|
| 3510 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B LYS 64 HD2 -0.344 3.104
|
|---|
| 3511 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 O 2D68.pdbqt #1/B SER 61 HB1 -0.355 2.815
|
|---|
| 3512 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 O 2D68.pdbqt #1/A GLY 124 O -0.356 3.296
|
|---|
| 3513 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B SER 61 CB -0.368 3.828
|
|---|
| 3514 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2D68.pdbqt #1/A PHE 84 CD1 -0.372 3.952
|
|---|
| 3515 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B LYS 64 CB -0.384 3.844
|
|---|
| 3516 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B LYS 64 HB1 -0.385 2.995
|
|---|
| 3517 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B SER 61 CA -0.390 3.970
|
|---|
| 3518 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B SER 61 HB1 -0.391 3.151
|
|---|
| 3519 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D68.pdbqt #1/B LYS 64 CB -0.395 3.705
|
|---|
| 3520 | 2D68--WRM-16.result.pdbqt #2.1/? UNL 1 O 2D68.pdbqt #1/B PHE 65 CB -0.395 3.555
|
|---|
| 3521 |
|
|---|
| 3522 |
|
|---|
| 3523 |
|
|---|
| 3524 | 45 contacts
|
|---|
| 3525 |
|
|---|
| 3526 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 3527 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2D68--
|
|---|
| 3528 | > WRM-16.hbonds.txt
|
|---|
| 3529 |
|
|---|
| 3530 |
|
|---|
| 3531 | Finding intermodel H-bonds
|
|---|
| 3532 | Finding intramodel H-bonds
|
|---|
| 3533 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 3534 | Models used:
|
|---|
| 3535 | 1 2D68.pdbqt
|
|---|
| 3536 | 2.1 2D68--WRM-16.result.pdbqt
|
|---|
| 3537 |
|
|---|
| 3538 | 0 H-bonds
|
|---|
| 3539 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 3540 |
|
|---|
| 3541 |
|
|---|
| 3542 |
|
|---|
| 3543 | 0 hydrogen bonds found
|
|---|
| 3544 |
|
|---|
| 3545 | > select :UNL
|
|---|
| 3546 |
|
|---|
| 3547 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 3548 |
|
|---|
| 3549 | > label sel text "Ligand "
|
|---|
| 3550 |
|
|---|
| 3551 | > label height 1
|
|---|
| 3552 |
|
|---|
| 3553 | > ~select
|
|---|
| 3554 |
|
|---|
| 3555 | Nothing selected
|
|---|
| 3556 |
|
|---|
| 3557 | > 2dlabels text "Binding Energy: -6.5 kcal/mol" color red size 18 xpos .03
|
|---|
| 3558 | > ypos .95
|
|---|
| 3559 |
|
|---|
| 3560 | > 2dlabels text "2D68 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 3561 |
|
|---|
| 3562 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2D68--
|
|---|
| 3563 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 3564 | > true
|
|---|
| 3565 |
|
|---|
| 3566 | > select :UNL
|
|---|
| 3567 |
|
|---|
| 3568 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 3569 |
|
|---|
| 3570 | > view sel
|
|---|
| 3571 |
|
|---|
| 3572 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2D68--
|
|---|
| 3573 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 3574 | > true
|
|---|
| 3575 |
|
|---|
| 3576 | > close
|
|---|
| 3577 |
|
|---|
| 3578 | > wait 5
|
|---|
| 3579 |
|
|---|
| 3580 | > set bgColor white
|
|---|
| 3581 |
|
|---|
| 3582 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1OW1.pdbqt
|
|---|
| 3583 |
|
|---|
| 3584 | Chain information for 1OW1.pdbqt #1
|
|---|
| 3585 | ---
|
|---|
| 3586 | Chain | Description
|
|---|
| 3587 | A | No description available
|
|---|
| 3588 |
|
|---|
| 3589 | Opened 1OW1.pdbqt containing 1 structures (2619 atoms, 2644 bonds)
|
|---|
| 3590 |
|
|---|
| 3591 | > wait 5
|
|---|
| 3592 |
|
|---|
| 3593 | > hide surfaces
|
|---|
| 3594 |
|
|---|
| 3595 | > hide atoms
|
|---|
| 3596 |
|
|---|
| 3597 | > show cartoons
|
|---|
| 3598 |
|
|---|
| 3599 | > wait 5
|
|---|
| 3600 |
|
|---|
| 3601 | > addh
|
|---|
| 3602 |
|
|---|
| 3603 | Summary of feedback from adding hydrogens to 1OW1.pdbqt #1
|
|---|
| 3604 | ---
|
|---|
| 3605 | notes | No usable SEQRES records for 1OW1.pdbqt (#1) chain A; guessing termini
|
|---|
| 3606 | instead
|
|---|
| 3607 | Chain-initial residues that are actual N termini: /A PRO 3495
|
|---|
| 3608 | Chain-initial residues that are not actual N termini: /A PRO 3545
|
|---|
| 3609 | Chain-final residues that are actual C termini: /A VAL 3664
|
|---|
| 3610 | Chain-final residues that are not actual C termini: /A SER 3541
|
|---|
| 3611 | 124 hydrogen bonds
|
|---|
| 3612 | /A SER 3541 is not terminus, removing H atom from 'C'
|
|---|
| 3613 | 0 hydrogens added
|
|---|
| 3614 |
|
|---|
| 3615 |
|
|---|
| 3616 | > wait 5
|
|---|
| 3617 |
|
|---|
| 3618 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1OW1--
|
|---|
| 3619 | > WRM-16.result.pdbqt
|
|---|
| 3620 |
|
|---|
| 3621 | Summary of feedback from opening
|
|---|
| 3622 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1OW1--WRM-16.result.pdbqt
|
|---|
| 3623 | ---
|
|---|
| 3624 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 3625 | REMARK VINA RESULT: -7.1 0.000 0.000
|
|---|
| 3626 |
|
|---|
| 3627 | Ignored bad PDB record found on line 3
|
|---|
| 3628 | REMARK 5 active torsions:
|
|---|
| 3629 |
|
|---|
| 3630 | Ignored bad PDB record found on line 4
|
|---|
| 3631 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 3632 |
|
|---|
| 3633 | Ignored bad PDB record found on line 5
|
|---|
| 3634 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 3635 |
|
|---|
| 3636 | Ignored bad PDB record found on line 6
|
|---|
| 3637 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 3638 |
|
|---|
| 3639 | 184 messages similar to the above omitted
|
|---|
| 3640 |
|
|---|
| 3641 | Opened 1OW1--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 3642 | bonds)
|
|---|
| 3643 |
|
|---|
| 3644 | > wait 5
|
|---|
| 3645 |
|
|---|
| 3646 | > close #2.2-9
|
|---|
| 3647 |
|
|---|
| 3648 | > wait 5
|
|---|
| 3649 |
|
|---|
| 3650 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 3651 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1OW1--
|
|---|
| 3652 | > WRM-16.contacts.txt
|
|---|
| 3653 |
|
|---|
| 3654 |
|
|---|
| 3655 | Allowed overlap: -0.4
|
|---|
| 3656 | H-bond overlap reduction: 0.4
|
|---|
| 3657 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 3658 | Detect intra-residue contacts: False
|
|---|
| 3659 | Detect intra-molecule contacts: True
|
|---|
| 3660 |
|
|---|
| 3661 | 54 contacts
|
|---|
| 3662 | atom1 atom2 overlap distance
|
|---|
| 3663 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A PRO 3631 HB2 0.457 2.423
|
|---|
| 3664 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A HIS 3656 HE1 0.285 2.595
|
|---|
| 3665 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A ILE 3600 1HG2 0.241 2.639
|
|---|
| 3666 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A LYS 3596 HD2 0.208 2.552
|
|---|
| 3667 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A HIS 3656 CE1 0.058 3.522
|
|---|
| 3668 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A ASN 3652 ND2 0.047 3.188
|
|---|
| 3669 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A PRO 3631 CB 0.042 3.538
|
|---|
| 3670 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A ASN 3652 1HD2 0.027 2.583
|
|---|
| 3671 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A GLN 3604 1HE2 0.008 2.602
|
|---|
| 3672 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A GLN 3604 1HE2 0.006 2.054
|
|---|
| 3673 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A GLU 3636 OE2 -0.046 3.286
|
|---|
| 3674 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A ILE 3600 CG2 -0.051 3.511
|
|---|
| 3675 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A PRO 3631 HG2 -0.056 2.936
|
|---|
| 3676 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A LYS 3596 CD -0.060 3.520
|
|---|
| 3677 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A PRO 3631 HB2 -0.069 2.679
|
|---|
| 3678 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A PRO 3655 HG1 -0.070 2.490
|
|---|
| 3679 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A ILE 3600 2HD1 -0.102 2.982
|
|---|
| 3680 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A ASN 3652 ND2 -0.113 2.798
|
|---|
| 3681 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A LYS 3596 HG1 -0.117 2.537
|
|---|
| 3682 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A ILE 3600 CG2 -0.123 3.703
|
|---|
| 3683 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1OW1.pdbqt #1/A THR 3601 OG1 -0.128 3.508
|
|---|
| 3684 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A ASN 3652 1HD2 -0.143 2.203
|
|---|
| 3685 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A GLN 3604 OE1 -0.160 3.400
|
|---|
| 3686 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A PRO 3631 CB -0.161 3.471
|
|---|
| 3687 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A GLU 3636 CD -0.162 3.622
|
|---|
| 3688 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A PRO 3631 HB1 -0.171 2.781
|
|---|
| 3689 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A ILE 3600 1HG2 -0.189 2.799
|
|---|
| 3690 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A PRO 3655 CG -0.210 3.330
|
|---|
| 3691 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A ILE 3600 1HG2 -0.214 2.974
|
|---|
| 3692 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A SER 3651 HA -0.252 3.132
|
|---|
| 3693 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A PRO 3631 HB1 -0.262 2.872
|
|---|
| 3694 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A ASN 3652 HN -0.264 2.284
|
|---|
| 3695 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A PRO 3631 CB -0.265 3.575
|
|---|
| 3696 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A PRO 3631 CB -0.274 3.584
|
|---|
| 3697 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A LYS 3596 CG -0.287 3.407
|
|---|
| 3698 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A GLN 3604 OE1 -0.287 3.527
|
|---|
| 3699 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A PRO 3655 CB -0.295 3.415
|
|---|
| 3700 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A ASN 3652 HN -0.297 2.357
|
|---|
| 3701 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A PRO 3631 CG -0.300 3.880
|
|---|
| 3702 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A PRO 3631 HB1 -0.312 2.922
|
|---|
| 3703 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A GLU 3636 CD -0.313 3.773
|
|---|
| 3704 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A LYS 3596 CG -0.322 3.782
|
|---|
| 3705 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A LYS 3596 HB1 -0.332 3.092
|
|---|
| 3706 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A ASN 3652 N -0.332 2.977
|
|---|
| 3707 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A GLN 3604 NE2 -0.343 3.578
|
|---|
| 3708 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A ILE 3600 3HG2 -0.343 3.103
|
|---|
| 3709 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A ASN 3652 CA -0.344 3.464
|
|---|
| 3710 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A ASN 3652 HN -0.347 3.227
|
|---|
| 3711 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A GLN 3604 NE2 -0.358 3.043
|
|---|
| 3712 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A LYS 3596 CD -0.367 3.487
|
|---|
| 3713 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A GLN 3604 NE2 -0.367 3.752
|
|---|
| 3714 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A ASN 3652 1HD2 -0.377 2.987
|
|---|
| 3715 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A PRO 3631 HB2 -0.377 2.987
|
|---|
| 3716 | 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OW1.pdbqt #1/A ASN 3652 HN -0.390 3.000
|
|---|
| 3717 |
|
|---|
| 3718 |
|
|---|
| 3719 |
|
|---|
| 3720 | 54 contacts
|
|---|
| 3721 |
|
|---|
| 3722 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 3723 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1OW1--
|
|---|
| 3724 | > WRM-16.hbonds.txt
|
|---|
| 3725 |
|
|---|
| 3726 |
|
|---|
| 3727 | Finding intermodel H-bonds
|
|---|
| 3728 | Finding intramodel H-bonds
|
|---|
| 3729 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 3730 | Models used:
|
|---|
| 3731 | 1 1OW1.pdbqt
|
|---|
| 3732 | 2.1 1OW1--WRM-16.result.pdbqt
|
|---|
| 3733 |
|
|---|
| 3734 | 2 H-bonds
|
|---|
| 3735 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 3736 | 1OW1.pdbqt #1/A GLN 3604 NE2 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A GLN 3604 1HE2 3.043 2.054
|
|---|
| 3737 | 1OW1.pdbqt #1/A ASN 3652 N 1OW1--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OW1.pdbqt #1/A ASN 3652 HN 3.284 2.357
|
|---|
| 3738 |
|
|---|
| 3739 |
|
|---|
| 3740 |
|
|---|
| 3741 | 2 hydrogen bonds found
|
|---|
| 3742 |
|
|---|
| 3743 | > select :UNL
|
|---|
| 3744 |
|
|---|
| 3745 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 3746 |
|
|---|
| 3747 | > label sel text "Ligand "
|
|---|
| 3748 |
|
|---|
| 3749 | > label height 1
|
|---|
| 3750 |
|
|---|
| 3751 | > ~select
|
|---|
| 3752 |
|
|---|
| 3753 | Nothing selected
|
|---|
| 3754 |
|
|---|
| 3755 | > 2dlabels text "Binding Energy: -7.1 kcal/mol" color red size 18 xpos .03
|
|---|
| 3756 | > ypos .95
|
|---|
| 3757 |
|
|---|
| 3758 | > 2dlabels text "1OW1 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 3759 |
|
|---|
| 3760 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1OW1--
|
|---|
| 3761 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 3762 | > true
|
|---|
| 3763 |
|
|---|
| 3764 | > select :UNL
|
|---|
| 3765 |
|
|---|
| 3766 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 3767 |
|
|---|
| 3768 | > view sel
|
|---|
| 3769 |
|
|---|
| 3770 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1OW1--
|
|---|
| 3771 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 3772 | > true
|
|---|
| 3773 |
|
|---|
| 3774 | > close
|
|---|
| 3775 |
|
|---|
| 3776 | > wait 5
|
|---|
| 3777 |
|
|---|
| 3778 | > set bgColor white
|
|---|
| 3779 |
|
|---|
| 3780 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1RJB.pdbqt
|
|---|
| 3781 |
|
|---|
| 3782 | Chain information for 1RJB.pdbqt #1
|
|---|
| 3783 | ---
|
|---|
| 3784 | Chain | Description
|
|---|
| 3785 | A | No description available
|
|---|
| 3786 |
|
|---|
| 3787 | Opened 1RJB.pdbqt containing 1 structures (4781 atoms, 4839 bonds)
|
|---|
| 3788 |
|
|---|
| 3789 | > wait 5
|
|---|
| 3790 |
|
|---|
| 3791 | > hide surfaces
|
|---|
| 3792 |
|
|---|
| 3793 | > hide atoms
|
|---|
| 3794 |
|
|---|
| 3795 | > show cartoons
|
|---|
| 3796 |
|
|---|
| 3797 | > wait 5
|
|---|
| 3798 |
|
|---|
| 3799 | > addh
|
|---|
| 3800 |
|
|---|
| 3801 | Summary of feedback from adding hydrogens to 1RJB.pdbqt #1
|
|---|
| 3802 | ---
|
|---|
| 3803 | notes | No usable SEQRES records for 1RJB.pdbqt (#1) chain A; guessing termini
|
|---|
| 3804 | instead
|
|---|
| 3805 | Chain-initial residues that are actual N termini: /A TYR 572
|
|---|
| 3806 | Chain-initial residues that are not actual N termini: /A ARG 655, /A LEU 783
|
|---|
| 3807 | Chain-final residues that are actual C termini: /A LEU 947
|
|---|
| 3808 | Chain-final residues that are not actual C termini: /A GLU 648, /A PHE 710
|
|---|
| 3809 | 249 hydrogen bonds
|
|---|
| 3810 | Adding 'H' to /A ARG 655
|
|---|
| 3811 | Adding 'H' to /A LEU 783
|
|---|
| 3812 | /A GLU 648 is not terminus, removing H atom from 'C'
|
|---|
| 3813 | /A PHE 710 is not terminus, removing H atom from 'C'
|
|---|
| 3814 | 3 hydrogens added
|
|---|
| 3815 |
|
|---|
| 3816 |
|
|---|
| 3817 | > wait 5
|
|---|
| 3818 |
|
|---|
| 3819 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1RJB--
|
|---|
| 3820 | > WRM-16.result.pdbqt
|
|---|
| 3821 |
|
|---|
| 3822 | Summary of feedback from opening
|
|---|
| 3823 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1RJB--WRM-16.result.pdbqt
|
|---|
| 3824 | ---
|
|---|
| 3825 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 3826 | REMARK VINA RESULT: -8.6 0.000 0.000
|
|---|
| 3827 |
|
|---|
| 3828 | Ignored bad PDB record found on line 3
|
|---|
| 3829 | REMARK 5 active torsions:
|
|---|
| 3830 |
|
|---|
| 3831 | Ignored bad PDB record found on line 4
|
|---|
| 3832 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 3833 |
|
|---|
| 3834 | Ignored bad PDB record found on line 5
|
|---|
| 3835 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 3836 |
|
|---|
| 3837 | Ignored bad PDB record found on line 6
|
|---|
| 3838 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 3839 |
|
|---|
| 3840 | 184 messages similar to the above omitted
|
|---|
| 3841 |
|
|---|
| 3842 | Opened 1RJB--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 3843 | bonds)
|
|---|
| 3844 |
|
|---|
| 3845 | > wait 5
|
|---|
| 3846 |
|
|---|
| 3847 | > close #2.2-9
|
|---|
| 3848 |
|
|---|
| 3849 | > wait 5
|
|---|
| 3850 |
|
|---|
| 3851 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 3852 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1RJB--
|
|---|
| 3853 | > WRM-16.contacts.txt
|
|---|
| 3854 |
|
|---|
| 3855 |
|
|---|
| 3856 | Allowed overlap: -0.4
|
|---|
| 3857 | H-bond overlap reduction: 0.4
|
|---|
| 3858 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 3859 | Detect intra-residue contacts: False
|
|---|
| 3860 | Detect intra-molecule contacts: True
|
|---|
| 3861 |
|
|---|
| 3862 | 51 contacts
|
|---|
| 3863 | atom1 atom2 overlap distance
|
|---|
| 3864 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A GLN 575 2HE2 0.378 2.502
|
|---|
| 3865 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ILE 836 2HG2 0.292 2.468
|
|---|
| 3866 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A GLN 575 NE2 0.238 3.267
|
|---|
| 3867 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A PHE 621 HE2 0.094 2.666
|
|---|
| 3868 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A TYR 865 HH 0.037 2.723
|
|---|
| 3869 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ARG 849 O 0.021 3.069
|
|---|
| 3870 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ILE 836 1HG1 -0.003 2.763
|
|---|
| 3871 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A GLN 575 CG -0.016 3.596
|
|---|
| 3872 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ALA 848 HB3 -0.091 2.851
|
|---|
| 3873 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ARG 849 HB1 -0.091 2.701
|
|---|
| 3874 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A GLN 575 CD -0.093 3.403
|
|---|
| 3875 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ILE 836 CG2 -0.117 3.577
|
|---|
| 3876 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ARG 849 HG1 -0.148 2.908
|
|---|
| 3877 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 O 1RJB.pdbqt #1/A ARG 810 HD2 -0.162 2.582
|
|---|
| 3878 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ARG 849 HN -0.174 2.784
|
|---|
| 3879 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ARG 849 HG1 -0.178 2.938
|
|---|
| 3880 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A LEU 850 1HD2 -0.179 2.939
|
|---|
| 3881 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 O 1RJB.pdbqt #1/A TYR 842 CE1 -0.179 3.339
|
|---|
| 3882 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A LEU 850 1HD2 -0.188 2.948
|
|---|
| 3883 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A PHE 621 CE2 -0.192 3.652
|
|---|
| 3884 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ILE 836 2HG2 -0.200 2.960
|
|---|
| 3885 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 O 1RJB.pdbqt #1/A ALA 848 HA -0.214 2.674
|
|---|
| 3886 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 O 1RJB.pdbqt #1/A ARG 810 CD -0.219 3.339
|
|---|
| 3887 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A GLN 575 HG2 -0.221 3.101
|
|---|
| 3888 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ARG 849 CG -0.223 3.683
|
|---|
| 3889 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 O 1RJB.pdbqt #1/A ASP 811 HB2 -0.228 2.648
|
|---|
| 3890 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 O 1RJB.pdbqt #1/A GLN 575 HG2 -0.230 2.650
|
|---|
| 3891 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ARG 849 CG -0.243 3.703
|
|---|
| 3892 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A LEU 850 CD2 -0.254 3.714
|
|---|
| 3893 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A GLN 575 HG1 -0.259 3.139
|
|---|
| 3894 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A GLN 575 CD -0.259 3.839
|
|---|
| 3895 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A TYR 865 OH -0.259 3.519
|
|---|
| 3896 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A GLN 575 OE1 -0.268 3.358
|
|---|
| 3897 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ARG 849 O -0.269 3.359
|
|---|
| 3898 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ALA 848 CB -0.277 3.737
|
|---|
| 3899 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ARG 849 O -0.297 3.387
|
|---|
| 3900 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ARG 849 O -0.301 3.391
|
|---|
| 3901 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ARG 849 HG2 -0.313 3.073
|
|---|
| 3902 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A GLN 575 NE2 -0.318 3.553
|
|---|
| 3903 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ARG 849 HB1 -0.331 3.091
|
|---|
| 3904 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A GLN 575 OE1 -0.332 3.692
|
|---|
| 3905 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A GLN 575 NE2 -0.352 3.857
|
|---|
| 3906 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A GLN 575 CD -0.357 3.667
|
|---|
| 3907 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A GLN 575 OE1 -0.366 3.726
|
|---|
| 3908 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 O 1RJB.pdbqt #1/A TYR 842 HE1 -0.375 2.835
|
|---|
| 3909 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 O 1RJB.pdbqt #1/A ARG 810 CZ -0.376 3.496
|
|---|
| 3910 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ASP 811 OD1 -0.387 3.747
|
|---|
| 3911 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A GLN 575 CD -0.389 3.969
|
|---|
| 3912 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ARG 849 HB1 -0.395 3.005
|
|---|
| 3913 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RJB.pdbqt #1/A ILE 836 CG1 -0.395 3.855
|
|---|
| 3914 | 1RJB--WRM-16.result.pdbqt #2.1/? UNL 1 O 1RJB.pdbqt #1/A ASP 811 CB -0.397 3.517
|
|---|
| 3915 |
|
|---|
| 3916 |
|
|---|
| 3917 |
|
|---|
| 3918 | 51 contacts
|
|---|
| 3919 |
|
|---|
| 3920 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 3921 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1RJB--
|
|---|
| 3922 | > WRM-16.hbonds.txt
|
|---|
| 3923 |
|
|---|
| 3924 |
|
|---|
| 3925 | Finding intermodel H-bonds
|
|---|
| 3926 | Finding intramodel H-bonds
|
|---|
| 3927 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 3928 | Models used:
|
|---|
| 3929 | 1 1RJB.pdbqt
|
|---|
| 3930 | 2.1 1RJB--WRM-16.result.pdbqt
|
|---|
| 3931 |
|
|---|
| 3932 | 0 H-bonds
|
|---|
| 3933 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 3934 |
|
|---|
| 3935 |
|
|---|
| 3936 |
|
|---|
| 3937 | 0 hydrogen bonds found
|
|---|
| 3938 |
|
|---|
| 3939 | > select :UNL
|
|---|
| 3940 |
|
|---|
| 3941 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 3942 |
|
|---|
| 3943 | > label sel text "Ligand "
|
|---|
| 3944 |
|
|---|
| 3945 | > label height 1
|
|---|
| 3946 |
|
|---|
| 3947 | > ~select
|
|---|
| 3948 |
|
|---|
| 3949 | Nothing selected
|
|---|
| 3950 |
|
|---|
| 3951 | > 2dlabels text "Binding Energy: -8.6 kcal/mol" color red size 18 xpos .03
|
|---|
| 3952 | > ypos .95
|
|---|
| 3953 |
|
|---|
| 3954 | > 2dlabels text "1RJB WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 3955 |
|
|---|
| 3956 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1RJB--
|
|---|
| 3957 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 3958 | > true
|
|---|
| 3959 |
|
|---|
| 3960 | > select :UNL
|
|---|
| 3961 |
|
|---|
| 3962 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 3963 |
|
|---|
| 3964 | > view sel
|
|---|
| 3965 |
|
|---|
| 3966 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1RJB--
|
|---|
| 3967 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 3968 | > true
|
|---|
| 3969 |
|
|---|
| 3970 | > close
|
|---|
| 3971 |
|
|---|
| 3972 | > wait 5
|
|---|
| 3973 |
|
|---|
| 3974 | > set bgColor white
|
|---|
| 3975 |
|
|---|
| 3976 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1IFR.pdbqt
|
|---|
| 3977 |
|
|---|
| 3978 | Chain information for 1IFR.pdbqt #1
|
|---|
| 3979 | ---
|
|---|
| 3980 | Chain | Description
|
|---|
| 3981 | A | No description available
|
|---|
| 3982 |
|
|---|
| 3983 | Opened 1IFR.pdbqt containing 1 structures (1747 atoms, 1765 bonds)
|
|---|
| 3984 |
|
|---|
| 3985 | > wait 5
|
|---|
| 3986 |
|
|---|
| 3987 | > hide surfaces
|
|---|
| 3988 |
|
|---|
| 3989 | > hide atoms
|
|---|
| 3990 |
|
|---|
| 3991 | > show cartoons
|
|---|
| 3992 |
|
|---|
| 3993 | > wait 5
|
|---|
| 3994 |
|
|---|
| 3995 | > addh
|
|---|
| 3996 |
|
|---|
| 3997 | Summary of feedback from adding hydrogens to 1IFR.pdbqt #1
|
|---|
| 3998 | ---
|
|---|
| 3999 | notes | No usable SEQRES records for 1IFR.pdbqt (#1) chain A; guessing termini
|
|---|
| 4000 | instead
|
|---|
| 4001 | Chain-initial residues that are actual N termini: /A GLY 432
|
|---|
| 4002 | Chain-initial residues that are not actual N termini:
|
|---|
| 4003 | Chain-final residues that are actual C termini: /A VAL 544
|
|---|
| 4004 | Chain-final residues that are not actual C termini:
|
|---|
| 4005 | 96 hydrogen bonds
|
|---|
| 4006 | 1 hydrogens added
|
|---|
| 4007 |
|
|---|
| 4008 |
|
|---|
| 4009 | > wait 5
|
|---|
| 4010 |
|
|---|
| 4011 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1IFR--
|
|---|
| 4012 | > WRM-16.result.pdbqt
|
|---|
| 4013 |
|
|---|
| 4014 | Summary of feedback from opening
|
|---|
| 4015 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1IFR--WRM-16.result.pdbqt
|
|---|
| 4016 | ---
|
|---|
| 4017 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 4018 | REMARK VINA RESULT: -6.7 0.000 0.000
|
|---|
| 4019 |
|
|---|
| 4020 | Ignored bad PDB record found on line 3
|
|---|
| 4021 | REMARK 5 active torsions:
|
|---|
| 4022 |
|
|---|
| 4023 | Ignored bad PDB record found on line 4
|
|---|
| 4024 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 4025 |
|
|---|
| 4026 | Ignored bad PDB record found on line 5
|
|---|
| 4027 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 4028 |
|
|---|
| 4029 | Ignored bad PDB record found on line 6
|
|---|
| 4030 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 4031 |
|
|---|
| 4032 | 184 messages similar to the above omitted
|
|---|
| 4033 |
|
|---|
| 4034 | Opened 1IFR--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 4035 | bonds)
|
|---|
| 4036 |
|
|---|
| 4037 | > wait 5
|
|---|
| 4038 |
|
|---|
| 4039 | > close #2.2-9
|
|---|
| 4040 |
|
|---|
| 4041 | > wait 5
|
|---|
| 4042 |
|
|---|
| 4043 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 4044 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1IFR--
|
|---|
| 4045 | > WRM-16.contacts.txt
|
|---|
| 4046 |
|
|---|
| 4047 |
|
|---|
| 4048 | Allowed overlap: -0.4
|
|---|
| 4049 | H-bond overlap reduction: 0.4
|
|---|
| 4050 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 4051 | Detect intra-residue contacts: False
|
|---|
| 4052 | Detect intra-molecule contacts: True
|
|---|
| 4053 |
|
|---|
| 4054 | 43 contacts
|
|---|
| 4055 | atom1 atom2 overlap distance
|
|---|
| 4056 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A TYR 481 HE1 0.513 2.367
|
|---|
| 4057 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A TYR 481 CE1 0.243 3.337
|
|---|
| 4058 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A PRO 484 HA 0.157 2.723
|
|---|
| 4059 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A ARG 482 HD2 0.117 2.643
|
|---|
| 4060 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A TRP 514 HE1 0.011 2.869
|
|---|
| 4061 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A HIS 506 CE1 -0.034 3.494
|
|---|
| 4062 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 O 1IFR.pdbqt #1/A TRP 514 HD1 -0.075 2.495
|
|---|
| 4063 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A ALA 516 HB1 -0.130 3.010
|
|---|
| 4064 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A ALA 516 CB -0.132 3.712
|
|---|
| 4065 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A HIS 506 CE1 -0.132 3.442
|
|---|
| 4066 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A ARG 482 CB -0.156 3.616
|
|---|
| 4067 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A PRO 484 CA -0.164 3.744
|
|---|
| 4068 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A ARG 482 CD -0.170 3.630
|
|---|
| 4069 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A VAL 513 O -0.173 3.533
|
|---|
| 4070 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A ARG 482 HB1 -0.177 2.937
|
|---|
| 4071 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A LYS 515 HN -0.199 2.809
|
|---|
| 4072 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A PRO 484 HG1 -0.203 2.963
|
|---|
| 4073 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A ARG 482 HB1 -0.212 2.972
|
|---|
| 4074 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A VAL 513 O -0.218 3.458
|
|---|
| 4075 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A TRP 514 NE1 -0.230 3.735
|
|---|
| 4076 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A HIS 506 CE1 -0.238 3.698
|
|---|
| 4077 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 O 1IFR.pdbqt #1/A LYS 515 HB2 -0.256 2.676
|
|---|
| 4078 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 O 1IFR.pdbqt #1/A LEU 512 HB1 -0.279 2.699
|
|---|
| 4079 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A ARG 482 HB1 -0.284 3.044
|
|---|
| 4080 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A TYR 481 OH -0.290 3.670
|
|---|
| 4081 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A TRP 514 HD1 -0.300 2.910
|
|---|
| 4082 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 O 1IFR.pdbqt #1/A PRO 484 HG1 -0.303 2.723
|
|---|
| 4083 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A ARG 482 CB -0.312 3.772
|
|---|
| 4084 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A HIS 506 NE2 -0.315 3.700
|
|---|
| 4085 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 O 1IFR.pdbqt #1/A PRO 484 HA -0.316 2.776
|
|---|
| 4086 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A HIS 506 CE1 -0.321 3.781
|
|---|
| 4087 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 O 1IFR.pdbqt #1/A ALA 516 HN -0.348 2.368
|
|---|
| 4088 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A ARG 482 CB -0.362 3.822
|
|---|
| 4089 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A ARG 482 HD2 -0.363 3.123
|
|---|
| 4090 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A ARG 482 HB1 -0.365 3.125
|
|---|
| 4091 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A HIS 506 ND1 -0.367 3.752
|
|---|
| 4092 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A TYR 481 CZ -0.368 3.948
|
|---|
| 4093 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A ARG 482 HB2 -0.368 3.128
|
|---|
| 4094 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A ARG 482 CD -0.382 3.842
|
|---|
| 4095 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A HIS 506 HE1 -0.384 2.994
|
|---|
| 4096 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 O 1IFR.pdbqt #1/A HIS 506 HE1 -0.385 2.805
|
|---|
| 4097 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 O 1IFR.pdbqt #1/A TRP 514 CD1 -0.396 3.516
|
|---|
| 4098 | 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 C 1IFR.pdbqt #1/A ARG 482 O -0.398 3.488
|
|---|
| 4099 |
|
|---|
| 4100 |
|
|---|
| 4101 |
|
|---|
| 4102 | 43 contacts
|
|---|
| 4103 |
|
|---|
| 4104 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 4105 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1IFR--
|
|---|
| 4106 | > WRM-16.hbonds.txt
|
|---|
| 4107 |
|
|---|
| 4108 |
|
|---|
| 4109 | Finding intermodel H-bonds
|
|---|
| 4110 | Finding intramodel H-bonds
|
|---|
| 4111 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 4112 | Models used:
|
|---|
| 4113 | 1 1IFR.pdbqt
|
|---|
| 4114 | 2.1 1IFR--WRM-16.result.pdbqt
|
|---|
| 4115 |
|
|---|
| 4116 | 2 H-bonds
|
|---|
| 4117 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 4118 | 1IFR.pdbqt #1/A LYS 515 N 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 O 1IFR.pdbqt #1/A LYS 515 HN 3.558 2.542
|
|---|
| 4119 | 1IFR.pdbqt #1/A ALA 516 N 1IFR--WRM-16.result.pdbqt #2.1/? UNL 1 O 1IFR.pdbqt #1/A ALA 516 HN 3.125 2.368
|
|---|
| 4120 |
|
|---|
| 4121 |
|
|---|
| 4122 |
|
|---|
| 4123 | 2 hydrogen bonds found
|
|---|
| 4124 |
|
|---|
| 4125 | > select :UNL
|
|---|
| 4126 |
|
|---|
| 4127 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 4128 |
|
|---|
| 4129 | > label sel text "Ligand "
|
|---|
| 4130 |
|
|---|
| 4131 | > label height 1
|
|---|
| 4132 |
|
|---|
| 4133 | > ~select
|
|---|
| 4134 |
|
|---|
| 4135 | Nothing selected
|
|---|
| 4136 |
|
|---|
| 4137 | > 2dlabels text "Binding Energy: -6.7 kcal/mol" color red size 18 xpos .03
|
|---|
| 4138 | > ypos .95
|
|---|
| 4139 |
|
|---|
| 4140 | > 2dlabels text "1IFR WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 4141 |
|
|---|
| 4142 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1IFR--
|
|---|
| 4143 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 4144 | > true
|
|---|
| 4145 |
|
|---|
| 4146 | > select :UNL
|
|---|
| 4147 |
|
|---|
| 4148 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 4149 |
|
|---|
| 4150 | > view sel
|
|---|
| 4151 |
|
|---|
| 4152 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1IFR--
|
|---|
| 4153 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 4154 | > true
|
|---|
| 4155 |
|
|---|
| 4156 | > close
|
|---|
| 4157 |
|
|---|
| 4158 | > wait 5
|
|---|
| 4159 |
|
|---|
| 4160 | > set bgColor white
|
|---|
| 4161 |
|
|---|
| 4162 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1DNQ.pdbqt
|
|---|
| 4163 |
|
|---|
| 4164 | Chain information for 1DNQ.pdbqt #1
|
|---|
| 4165 | ---
|
|---|
| 4166 | Chain | Description
|
|---|
| 4167 | A | No description available
|
|---|
| 4168 |
|
|---|
| 4169 | Opened 1DNQ.pdbqt containing 1 structures (4770 atoms, 4812 bonds)
|
|---|
| 4170 |
|
|---|
| 4171 | > wait 5
|
|---|
| 4172 |
|
|---|
| 4173 | > hide surfaces
|
|---|
| 4174 |
|
|---|
| 4175 | > hide atoms
|
|---|
| 4176 |
|
|---|
| 4177 | > show cartoons
|
|---|
| 4178 |
|
|---|
| 4179 | > wait 5
|
|---|
| 4180 |
|
|---|
| 4181 | > addh
|
|---|
| 4182 |
|
|---|
| 4183 | Summary of feedback from adding hydrogens to 1DNQ.pdbqt #1
|
|---|
| 4184 | ---
|
|---|
| 4185 | notes | No usable SEQRES records for 1DNQ.pdbqt (#1) chain A; guessing termini
|
|---|
| 4186 | instead
|
|---|
| 4187 | Chain-initial residues that are actual N termini: /A LEU 1
|
|---|
| 4188 | Chain-initial residues that are not actual N termini:
|
|---|
| 4189 | Chain-final residues that are actual C termini: /A VAL 312
|
|---|
| 4190 | Chain-final residues that are not actual C termini:
|
|---|
| 4191 | 155 hydrogen bonds
|
|---|
| 4192 | 26 hydrogens added
|
|---|
| 4193 |
|
|---|
| 4194 |
|
|---|
| 4195 | > wait 5
|
|---|
| 4196 |
|
|---|
| 4197 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1DNQ--
|
|---|
| 4198 | > WRM-16.result.pdbqt
|
|---|
| 4199 |
|
|---|
| 4200 | Summary of feedback from opening
|
|---|
| 4201 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1DNQ--WRM-16.result.pdbqt
|
|---|
| 4202 | ---
|
|---|
| 4203 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 4204 | REMARK VINA RESULT: -7.9 0.000 0.000
|
|---|
| 4205 |
|
|---|
| 4206 | Ignored bad PDB record found on line 3
|
|---|
| 4207 | REMARK 5 active torsions:
|
|---|
| 4208 |
|
|---|
| 4209 | Ignored bad PDB record found on line 4
|
|---|
| 4210 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 4211 |
|
|---|
| 4212 | Ignored bad PDB record found on line 5
|
|---|
| 4213 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 4214 |
|
|---|
| 4215 | Ignored bad PDB record found on line 6
|
|---|
| 4216 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 4217 |
|
|---|
| 4218 | 184 messages similar to the above omitted
|
|---|
| 4219 |
|
|---|
| 4220 | Opened 1DNQ--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 4221 | bonds)
|
|---|
| 4222 |
|
|---|
| 4223 | > wait 5
|
|---|
| 4224 |
|
|---|
| 4225 | > close #2.2-9
|
|---|
| 4226 |
|
|---|
| 4227 | > wait 5
|
|---|
| 4228 |
|
|---|
| 4229 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 4230 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1DNQ--
|
|---|
| 4231 | > WRM-16.contacts.txt
|
|---|
| 4232 |
|
|---|
| 4233 |
|
|---|
| 4234 | Allowed overlap: -0.4
|
|---|
| 4235 | H-bond overlap reduction: 0.4
|
|---|
| 4236 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 4237 | Detect intra-residue contacts: False
|
|---|
| 4238 | Detect intra-molecule contacts: True
|
|---|
| 4239 |
|
|---|
| 4240 | 44 contacts
|
|---|
| 4241 | atom1 atom2 overlap distance
|
|---|
| 4242 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1DNQ.pdbqt #1/A TYR 45 HN 0.298 2.582
|
|---|
| 4243 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 101 CD1 0.113 3.467
|
|---|
| 4244 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 45 HD1 0.112 2.648
|
|---|
| 4245 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 O 1DNQ.pdbqt #1/A ASN 70 1HD2 0.109 1.911
|
|---|
| 4246 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A LYS 105 HG2 0.095 2.665
|
|---|
| 4247 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A ALA 68 HB2 0.074 2.686
|
|---|
| 4248 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1DNQ.pdbqt #1/A TYR 45 N 0.071 3.434
|
|---|
| 4249 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 45 HD1 -0.020 2.780
|
|---|
| 4250 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1DNQ.pdbqt #1/A TYR 45 HB1 -0.041 2.921
|
|---|
| 4251 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 45 HA -0.076 2.836
|
|---|
| 4252 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 45 HD1 -0.088 2.698
|
|---|
| 4253 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 45 HD1 -0.089 2.849
|
|---|
| 4254 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 101 HD1 -0.098 2.978
|
|---|
| 4255 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A LYS 105 HA -0.117 2.877
|
|---|
| 4256 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 O 1DNQ.pdbqt #1/A TYR 45 HE1 -0.135 2.555
|
|---|
| 4257 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 101 CE2 -0.142 3.452
|
|---|
| 4258 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A ALA 68 CB -0.172 3.632
|
|---|
| 4259 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A LYS 105 CG -0.199 3.659
|
|---|
| 4260 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 45 HD1 -0.208 2.968
|
|---|
| 4261 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A ASN 70 1HD2 -0.212 2.822
|
|---|
| 4262 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1DNQ.pdbqt #1/A TYR 45 CB -0.218 3.798
|
|---|
| 4263 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A ASN 104 C -0.227 3.687
|
|---|
| 4264 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A LYS 105 CA -0.229 3.689
|
|---|
| 4265 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 45 CA -0.237 3.697
|
|---|
| 4266 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A LYS 105 N -0.252 3.637
|
|---|
| 4267 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 45 CD1 -0.253 3.713
|
|---|
| 4268 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1DNQ.pdbqt #1/A ALA 68 HB3 -0.257 3.137
|
|---|
| 4269 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 45 CD1 -0.260 3.720
|
|---|
| 4270 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1DNQ.pdbqt #1/A ALA 68 CB -0.260 3.840
|
|---|
| 4271 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 O 1DNQ.pdbqt #1/A ASN 70 ND2 -0.271 2.916
|
|---|
| 4272 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A ASN 70 OD1 -0.279 3.519
|
|---|
| 4273 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1DNQ.pdbqt #1/A TYR 45 CA -0.290 3.870
|
|---|
| 4274 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A LYS 105 HA -0.291 3.051
|
|---|
| 4275 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 101 CD2 -0.304 3.614
|
|---|
| 4276 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 45 HD1 -0.326 2.936
|
|---|
| 4277 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 101 CZ -0.334 3.644
|
|---|
| 4278 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 45 CD1 -0.353 3.663
|
|---|
| 4279 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 45 HB1 -0.356 2.966
|
|---|
| 4280 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A ASN 70 OD1 -0.365 3.455
|
|---|
| 4281 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 101 CE2 -0.368 3.678
|
|---|
| 4282 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 45 CD1 -0.383 3.843
|
|---|
| 4283 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A TYR 45 CD1 -0.385 3.845
|
|---|
| 4284 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A ALA 68 C -0.385 3.845
|
|---|
| 4285 | 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 C 1DNQ.pdbqt #1/A ALA 103 O -0.388 3.628
|
|---|
| 4286 |
|
|---|
| 4287 |
|
|---|
| 4288 |
|
|---|
| 4289 | 44 contacts
|
|---|
| 4290 |
|
|---|
| 4291 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 4292 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1DNQ--
|
|---|
| 4293 | > WRM-16.hbonds.txt
|
|---|
| 4294 |
|
|---|
| 4295 |
|
|---|
| 4296 | Finding intermodel H-bonds
|
|---|
| 4297 | Finding intramodel H-bonds
|
|---|
| 4298 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 4299 | Models used:
|
|---|
| 4300 | 1 1DNQ.pdbqt
|
|---|
| 4301 | 2.1 1DNQ--WRM-16.result.pdbqt
|
|---|
| 4302 |
|
|---|
| 4303 | 1 H-bonds
|
|---|
| 4304 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 4305 | 1DNQ.pdbqt #1/A ASN 70 ND2 1DNQ--WRM-16.result.pdbqt #2.1/? UNL 1 O 1DNQ.pdbqt #1/A ASN 70 1HD2 2.916 1.911
|
|---|
| 4306 |
|
|---|
| 4307 |
|
|---|
| 4308 |
|
|---|
| 4309 | 1 hydrogen bonds found
|
|---|
| 4310 |
|
|---|
| 4311 | > select :UNL
|
|---|
| 4312 |
|
|---|
| 4313 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 4314 |
|
|---|
| 4315 | > label sel text "Ligand "
|
|---|
| 4316 |
|
|---|
| 4317 | > label height 1
|
|---|
| 4318 |
|
|---|
| 4319 | > ~select
|
|---|
| 4320 |
|
|---|
| 4321 | Nothing selected
|
|---|
| 4322 |
|
|---|
| 4323 | > 2dlabels text "Binding Energy: -7.9 kcal/mol" color red size 18 xpos .03
|
|---|
| 4324 | > ypos .95
|
|---|
| 4325 |
|
|---|
| 4326 | > 2dlabels text "1DNQ WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 4327 |
|
|---|
| 4328 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1DNQ--
|
|---|
| 4329 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 4330 | > true
|
|---|
| 4331 |
|
|---|
| 4332 | > select :UNL
|
|---|
| 4333 |
|
|---|
| 4334 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 4335 |
|
|---|
| 4336 | > view sel
|
|---|
| 4337 |
|
|---|
| 4338 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1DNQ--
|
|---|
| 4339 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 4340 | > true
|
|---|
| 4341 |
|
|---|
| 4342 | > close
|
|---|
| 4343 |
|
|---|
| 4344 | > wait 5
|
|---|
| 4345 |
|
|---|
| 4346 | > set bgColor white
|
|---|
| 4347 |
|
|---|
| 4348 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/3U84.pdbqt
|
|---|
| 4349 |
|
|---|
| 4350 | Chain information for 3U84.pdbqt #1
|
|---|
| 4351 | ---
|
|---|
| 4352 | Chain | Description
|
|---|
| 4353 | A | No description available
|
|---|
| 4354 | B | No description available
|
|---|
| 4355 |
|
|---|
| 4356 | Opened 3U84.pdbqt containing 1 structures (15424 atoms, 15596 bonds)
|
|---|
| 4357 |
|
|---|
| 4358 | > wait 5
|
|---|
| 4359 |
|
|---|
| 4360 | > hide surfaces
|
|---|
| 4361 |
|
|---|
| 4362 | > hide atoms
|
|---|
| 4363 |
|
|---|
| 4364 | > show cartoons
|
|---|
| 4365 |
|
|---|
| 4366 | > wait 5
|
|---|
| 4367 |
|
|---|
| 4368 | > addh
|
|---|
| 4369 |
|
|---|
| 4370 | Summary of feedback from adding hydrogens to 3U84.pdbqt #1
|
|---|
| 4371 | ---
|
|---|
| 4372 | warnings | Not adding hydrogens to /B ARG 206 CB because it is missing heavy-
|
|---|
| 4373 | atom bond partners
|
|---|
| 4374 | Not adding hydrogens to /B ARG 207 CB because it is missing heavy-atom bond
|
|---|
| 4375 | partners
|
|---|
| 4376 | notes | No usable SEQRES records for 3U84.pdbqt (#1) chain A; guessing termini
|
|---|
| 4377 | instead
|
|---|
| 4378 | No usable SEQRES records for 3U84.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 4379 | Chain-initial residues that are actual N termini: /A SER 1, /B GLY 2
|
|---|
| 4380 | Chain-initial residues that are not actual N termini: /A SER 402, /A THR 534,
|
|---|
| 4381 | /A GLY 548, /A SER 596, /B LEU 75, /B ARG 206, /B SER 402, /B ALA 523, /B GLY
|
|---|
| 4382 | 548
|
|---|
| 4383 | Chain-final residues that are actual C termini: /A LYS 608, /B ALA 581
|
|---|
| 4384 | Chain-final residues that are not actual C termini: /A GLY 386, /A GLY 528, /A
|
|---|
| 4385 | ALA 539, /A ALA 581, /B ASP 70, /B HIS 199, /B ALA 385, /B SER 459, /B GLY 528
|
|---|
| 4386 | 784 hydrogen bonds
|
|---|
| 4387 | Adding 'H' to /A SER 402
|
|---|
| 4388 | Adding 'H' to /A THR 534
|
|---|
| 4389 | Adding 'H' to /A GLY 548
|
|---|
| 4390 | Adding 'H' to /A SER 596
|
|---|
| 4391 | Adding 'H' to /B LEU 75
|
|---|
| 4392 | 4 messages similar to the above omitted
|
|---|
| 4393 | /A GLY 386 is not terminus, removing H atom from 'C'
|
|---|
| 4394 | /A GLY 528 is not terminus, removing H atom from 'C'
|
|---|
| 4395 | /A ALA 539 is not terminus, removing H atom from 'C'
|
|---|
| 4396 | /A ALA 581 is not terminus, removing H atom from 'C'
|
|---|
| 4397 | /B ASP 70 is not terminus, removing H atom from 'C'
|
|---|
| 4398 | 4 messages similar to the above omitted
|
|---|
| 4399 | -13 hydrogens added
|
|---|
| 4400 |
|
|---|
| 4401 |
|
|---|
| 4402 | > wait 5
|
|---|
| 4403 |
|
|---|
| 4404 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/3U84--
|
|---|
| 4405 | > WRM-16.result.pdbqt
|
|---|
| 4406 |
|
|---|
| 4407 | Summary of feedback from opening
|
|---|
| 4408 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/3U84--WRM-16.result.pdbqt
|
|---|
| 4409 | ---
|
|---|
| 4410 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 4411 | REMARK VINA RESULT: -7.5 0.000 0.000
|
|---|
| 4412 |
|
|---|
| 4413 | Ignored bad PDB record found on line 3
|
|---|
| 4414 | REMARK 5 active torsions:
|
|---|
| 4415 |
|
|---|
| 4416 | Ignored bad PDB record found on line 4
|
|---|
| 4417 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 4418 |
|
|---|
| 4419 | Ignored bad PDB record found on line 5
|
|---|
| 4420 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 4421 |
|
|---|
| 4422 | Ignored bad PDB record found on line 6
|
|---|
| 4423 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 4424 |
|
|---|
| 4425 | 184 messages similar to the above omitted
|
|---|
| 4426 |
|
|---|
| 4427 | Opened 3U84--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 4428 | bonds)
|
|---|
| 4429 |
|
|---|
| 4430 | > wait 5
|
|---|
| 4431 |
|
|---|
| 4432 | > close #2.2-9
|
|---|
| 4433 |
|
|---|
| 4434 | > wait 5
|
|---|
| 4435 |
|
|---|
| 4436 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 4437 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3U84--
|
|---|
| 4438 | > WRM-16.contacts.txt
|
|---|
| 4439 |
|
|---|
| 4440 |
|
|---|
| 4441 | Allowed overlap: -0.4
|
|---|
| 4442 | H-bond overlap reduction: 0.4
|
|---|
| 4443 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 4444 | Detect intra-residue contacts: False
|
|---|
| 4445 | Detect intra-molecule contacts: True
|
|---|
| 4446 |
|
|---|
| 4447 | 37 contacts
|
|---|
| 4448 | atom1 atom2 overlap distance
|
|---|
| 4449 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 O 3U84.pdbqt #1/B MET 322 HB2 0.433 2.027
|
|---|
| 4450 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B TRP 341 HZ2 0.260 2.620
|
|---|
| 4451 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B VAL 371 1HG1 0.250 2.630
|
|---|
| 4452 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B GLY 326 HA1 0.185 2.695
|
|---|
| 4453 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B CYS 329 HG 0.091 2.789
|
|---|
| 4454 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 O 3U84.pdbqt #1/B MET 322 CB 0.060 3.100
|
|---|
| 4455 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B GLU 363 OE2 -0.030 3.390
|
|---|
| 4456 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B TYR 319 CD2 -0.086 3.546
|
|---|
| 4457 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B VAL 371 CG1 -0.103 3.683
|
|---|
| 4458 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 O 3U84.pdbqt #1/B TRP 341 HE1 -0.116 2.136
|
|---|
| 4459 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B TRP 341 CZ2 -0.126 3.706
|
|---|
| 4460 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 O 3U84.pdbqt #1/B MET 322 HB1 -0.165 2.585
|
|---|
| 4461 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B GLY 326 CA -0.175 3.755
|
|---|
| 4462 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B MET 322 HB2 -0.189 3.069
|
|---|
| 4463 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 O 3U84.pdbqt #1/B MET 322 O -0.208 3.148
|
|---|
| 4464 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B TYR 323 CE1 -0.214 3.674
|
|---|
| 4465 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 O 3U84.pdbqt #1/B VAL 371 1HG2 -0.215 2.675
|
|---|
| 4466 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B TYR 323 CE2 -0.234 3.694
|
|---|
| 4467 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B CYS 329 SG -0.241 3.903
|
|---|
| 4468 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 O 3U84.pdbqt #1/B MET 322 CB -0.245 3.365
|
|---|
| 4469 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B TYR 323 HA -0.261 3.141
|
|---|
| 4470 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 O 3U84.pdbqt #1/B MET 322 C -0.269 3.429
|
|---|
| 4471 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B TYR 319 CE2 -0.282 3.742
|
|---|
| 4472 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B TYR 323 CZ -0.292 3.752
|
|---|
| 4473 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B TYR 323 CZ -0.312 3.772
|
|---|
| 4474 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 O 3U84.pdbqt #1/B TYR 323 CD2 -0.317 3.437
|
|---|
| 4475 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 O 3U84.pdbqt #1/B MET 322 C -0.325 3.445
|
|---|
| 4476 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B TYR 323 OH -0.327 3.587
|
|---|
| 4477 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B TYR 323 OH -0.330 3.440
|
|---|
| 4478 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B MET 322 C -0.334 3.914
|
|---|
| 4479 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B TYR 319 CG -0.349 3.809
|
|---|
| 4480 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B TYR 323 OH -0.353 3.613
|
|---|
| 4481 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B TYR 323 CZ -0.360 3.670
|
|---|
| 4482 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 O 3U84.pdbqt #1/B TYR 323 N -0.378 3.023
|
|---|
| 4483 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B MET 322 HB2 -0.382 2.992
|
|---|
| 4484 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B GLU 363 OE2 -0.387 3.477
|
|---|
| 4485 | 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 C 3U84.pdbqt #1/B MET 322 O -0.399 3.759
|
|---|
| 4486 |
|
|---|
| 4487 |
|
|---|
| 4488 |
|
|---|
| 4489 | 37 contacts
|
|---|
| 4490 |
|
|---|
| 4491 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 4492 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3U84--
|
|---|
| 4493 | > WRM-16.hbonds.txt
|
|---|
| 4494 |
|
|---|
| 4495 |
|
|---|
| 4496 | Finding intermodel H-bonds
|
|---|
| 4497 | Finding intramodel H-bonds
|
|---|
| 4498 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 4499 | Models used:
|
|---|
| 4500 | 1 3U84.pdbqt
|
|---|
| 4501 | 2.1 3U84--WRM-16.result.pdbqt
|
|---|
| 4502 |
|
|---|
| 4503 | 1 H-bonds
|
|---|
| 4504 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 4505 | 3U84.pdbqt #1/B TRP 341 NE1 3U84--WRM-16.result.pdbqt #2.1/? UNL 1 O 3U84.pdbqt #1/B TRP 341 HE1 3.103 2.136
|
|---|
| 4506 |
|
|---|
| 4507 |
|
|---|
| 4508 |
|
|---|
| 4509 | 1 hydrogen bonds found
|
|---|
| 4510 |
|
|---|
| 4511 | > select :UNL
|
|---|
| 4512 |
|
|---|
| 4513 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 4514 |
|
|---|
| 4515 | > label sel text "Ligand "
|
|---|
| 4516 |
|
|---|
| 4517 | > label height 1
|
|---|
| 4518 |
|
|---|
| 4519 | > ~select
|
|---|
| 4520 |
|
|---|
| 4521 | Nothing selected
|
|---|
| 4522 |
|
|---|
| 4523 | > 2dlabels text "Binding Energy: -7.5 kcal/mol" color red size 18 xpos .03
|
|---|
| 4524 | > ypos .95
|
|---|
| 4525 |
|
|---|
| 4526 | > 2dlabels text "3U84 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 4527 |
|
|---|
| 4528 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3U84--
|
|---|
| 4529 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 4530 | > true
|
|---|
| 4531 |
|
|---|
| 4532 | > select :UNL
|
|---|
| 4533 |
|
|---|
| 4534 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 4535 |
|
|---|
| 4536 | > view sel
|
|---|
| 4537 |
|
|---|
| 4538 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3U84--
|
|---|
| 4539 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 4540 | > true
|
|---|
| 4541 |
|
|---|
| 4542 | > close
|
|---|
| 4543 |
|
|---|
| 4544 | > wait 5
|
|---|
| 4545 |
|
|---|
| 4546 | > set bgColor white
|
|---|
| 4547 |
|
|---|
| 4548 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/2YSM.pdbqt
|
|---|
| 4549 |
|
|---|
| 4550 | Chain information for 2YSM.pdbqt #1
|
|---|
| 4551 | ---
|
|---|
| 4552 | Chain | Description
|
|---|
| 4553 | A | No description available
|
|---|
| 4554 |
|
|---|
| 4555 | Opened 2YSM.pdbqt containing 1 structures (1584 atoms, 1601 bonds)
|
|---|
| 4556 |
|
|---|
| 4557 | > wait 5
|
|---|
| 4558 |
|
|---|
| 4559 | > hide surfaces
|
|---|
| 4560 |
|
|---|
| 4561 | > hide atoms
|
|---|
| 4562 |
|
|---|
| 4563 | > show cartoons
|
|---|
| 4564 |
|
|---|
| 4565 | > wait 5
|
|---|
| 4566 |
|
|---|
| 4567 | > addh
|
|---|
| 4568 |
|
|---|
| 4569 | Summary of feedback from adding hydrogens to 2YSM.pdbqt #1
|
|---|
| 4570 | ---
|
|---|
| 4571 | notes | No usable SEQRES records for 2YSM.pdbqt (#1) chain A; guessing termini
|
|---|
| 4572 | instead
|
|---|
| 4573 | Chain-initial residues that are actual N termini: /A GLY 1
|
|---|
| 4574 | Chain-initial residues that are not actual N termini:
|
|---|
| 4575 | Chain-final residues that are actual C termini: /A GLY 111
|
|---|
| 4576 | Chain-final residues that are not actual C termini:
|
|---|
| 4577 | 29 hydrogen bonds
|
|---|
| 4578 | 15 hydrogens added
|
|---|
| 4579 |
|
|---|
| 4580 |
|
|---|
| 4581 | > wait 5
|
|---|
| 4582 |
|
|---|
| 4583 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2YSM--
|
|---|
| 4584 | > WRM-16.result.pdbqt
|
|---|
| 4585 |
|
|---|
| 4586 | Summary of feedback from opening
|
|---|
| 4587 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2YSM--WRM-16.result.pdbqt
|
|---|
| 4588 | ---
|
|---|
| 4589 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 4590 | REMARK VINA RESULT: -7.5 0.000 0.000
|
|---|
| 4591 |
|
|---|
| 4592 | Ignored bad PDB record found on line 3
|
|---|
| 4593 | REMARK 5 active torsions:
|
|---|
| 4594 |
|
|---|
| 4595 | Ignored bad PDB record found on line 4
|
|---|
| 4596 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 4597 |
|
|---|
| 4598 | Ignored bad PDB record found on line 5
|
|---|
| 4599 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 4600 |
|
|---|
| 4601 | Ignored bad PDB record found on line 6
|
|---|
| 4602 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 4603 |
|
|---|
| 4604 | 184 messages similar to the above omitted
|
|---|
| 4605 |
|
|---|
| 4606 | Opened 2YSM--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 4607 | bonds)
|
|---|
| 4608 |
|
|---|
| 4609 | > wait 5
|
|---|
| 4610 |
|
|---|
| 4611 | > close #2.2-9
|
|---|
| 4612 |
|
|---|
| 4613 | > wait 5
|
|---|
| 4614 |
|
|---|
| 4615 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 4616 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2YSM--
|
|---|
| 4617 | > WRM-16.contacts.txt
|
|---|
| 4618 |
|
|---|
| 4619 |
|
|---|
| 4620 | Allowed overlap: -0.4
|
|---|
| 4621 | H-bond overlap reduction: 0.4
|
|---|
| 4622 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 4623 | Detect intra-residue contacts: False
|
|---|
| 4624 | Detect intra-molecule contacts: True
|
|---|
| 4625 |
|
|---|
| 4626 | 58 contacts
|
|---|
| 4627 | atom1 atom2 overlap distance
|
|---|
| 4628 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2YSM.pdbqt #1/A PRO 92 HG2 0.549 2.331
|
|---|
| 4629 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2YSM.pdbqt #1/A TRP 96 HB2 0.263 2.617
|
|---|
| 4630 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2YSM.pdbqt #1/A PRO 92 CG 0.262 3.318
|
|---|
| 4631 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A ILE 39 2HG1 0.200 2.560
|
|---|
| 4632 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 H 0.194 2.566
|
|---|
| 4633 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2YSM.pdbqt #1/A ASN 94 CA 0.171 3.409
|
|---|
| 4634 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2YSM.pdbqt #1/A ASN 94 HA 0.167 2.713
|
|---|
| 4635 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A ILE 39 2HG1 0.075 2.685
|
|---|
| 4636 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A LEU 70 3HD2 0.068 2.692
|
|---|
| 4637 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A PRO 52 HB3 0.066 2.814
|
|---|
| 4638 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2YSM.pdbqt #1/A TRP 96 CB 0.017 3.563
|
|---|
| 4639 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A LYS 55 HZ1 0.014 2.866
|
|---|
| 4640 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2YSM.pdbqt #1/A ASN 94 C -0.022 3.602
|
|---|
| 4641 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 2HG1 -0.039 2.919
|
|---|
| 4642 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 CG2 -0.053 3.633
|
|---|
| 4643 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 HB -0.053 2.933
|
|---|
| 4644 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2YSM.pdbqt #1/A ASN 94 N -0.094 3.599
|
|---|
| 4645 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 HB -0.109 2.719
|
|---|
| 4646 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A MET 69 O -0.119 3.479
|
|---|
| 4647 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 3HG1 -0.129 2.739
|
|---|
| 4648 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A LEU 70 3HD2 -0.130 2.890
|
|---|
| 4649 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 CB -0.136 3.716
|
|---|
| 4650 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2YSM.pdbqt #1/A PRO 92 CB -0.142 3.722
|
|---|
| 4651 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 HB -0.142 2.752
|
|---|
| 4652 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2YSM.pdbqt #1/A GLY 95 N -0.146 3.651
|
|---|
| 4653 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A ILE 39 CG1 -0.151 3.611
|
|---|
| 4654 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2YSM.pdbqt #1/A PRO 92 O -0.156 3.516
|
|---|
| 4655 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 N -0.158 3.543
|
|---|
| 4656 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A PRO 92 O -0.216 3.456
|
|---|
| 4657 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 3HG1 -0.219 2.829
|
|---|
| 4658 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 CG1 -0.219 3.529
|
|---|
| 4659 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2YSM.pdbqt #1/A THR 93 C -0.221 3.801
|
|---|
| 4660 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A LEU 70 CD2 -0.255 3.715
|
|---|
| 4661 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A LEU 70 CD2 -0.258 3.718
|
|---|
| 4662 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A ASP 76 OD1 -0.259 3.499
|
|---|
| 4663 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2YSM.pdbqt #1/A PRO 92 C -0.264 3.844
|
|---|
| 4664 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 2HG2 -0.266 3.146
|
|---|
| 4665 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A ILE 39 CG1 -0.271 3.731
|
|---|
| 4666 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 2HG2 -0.280 2.890
|
|---|
| 4667 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A PRO 52 CB -0.282 3.862
|
|---|
| 4668 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 2HG2 -0.286 2.896
|
|---|
| 4669 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A LEU 70 HA -0.289 3.049
|
|---|
| 4670 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A ASP 73 OD1 -0.292 3.532
|
|---|
| 4671 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 N -0.297 3.802
|
|---|
| 4672 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 CG1 -0.297 3.877
|
|---|
| 4673 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 CG1 -0.299 3.609
|
|---|
| 4674 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2YSM.pdbqt #1/A PRO 92 HB2 -0.302 3.182
|
|---|
| 4675 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 3HG1 -0.309 3.069
|
|---|
| 4676 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A TRP 96 CB -0.331 3.791
|
|---|
| 4677 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 H -0.335 3.215
|
|---|
| 4678 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 CB -0.338 3.648
|
|---|
| 4679 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A LYS 45 HZ3 -0.358 3.118
|
|---|
| 4680 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A PRO 92 HG2 -0.359 2.969
|
|---|
| 4681 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A THR 93 O -0.359 3.599
|
|---|
| 4682 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2YSM.pdbqt #1/A TRP 96 N -0.383 3.888
|
|---|
| 4683 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A LYS 55 NZ -0.384 3.889
|
|---|
| 4684 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A VAL 71 CB -0.385 3.695
|
|---|
| 4685 | 2YSM--WRM-16.result.pdbqt #2.1/? UNL 1 C 2YSM.pdbqt #1/A ASP 76 OD1 -0.395 3.635
|
|---|
| 4686 |
|
|---|
| 4687 |
|
|---|
| 4688 |
|
|---|
| 4689 | 58 contacts
|
|---|
| 4690 |
|
|---|
| 4691 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 4692 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2YSM--
|
|---|
| 4693 | > WRM-16.hbonds.txt
|
|---|
| 4694 |
|
|---|
| 4695 |
|
|---|
| 4696 | Finding intermodel H-bonds
|
|---|
| 4697 | Finding intramodel H-bonds
|
|---|
| 4698 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 4699 | Models used:
|
|---|
| 4700 | 1 2YSM.pdbqt
|
|---|
| 4701 | 2.1 2YSM--WRM-16.result.pdbqt
|
|---|
| 4702 |
|
|---|
| 4703 | 0 H-bonds
|
|---|
| 4704 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 4705 |
|
|---|
| 4706 |
|
|---|
| 4707 |
|
|---|
| 4708 | 0 hydrogen bonds found
|
|---|
| 4709 |
|
|---|
| 4710 | > select :UNL
|
|---|
| 4711 |
|
|---|
| 4712 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 4713 |
|
|---|
| 4714 | > label sel text "Ligand "
|
|---|
| 4715 |
|
|---|
| 4716 | > label height 1
|
|---|
| 4717 |
|
|---|
| 4718 | > ~select
|
|---|
| 4719 |
|
|---|
| 4720 | Nothing selected
|
|---|
| 4721 |
|
|---|
| 4722 | > 2dlabels text "Binding Energy: -7.5 kcal/mol" color red size 18 xpos .03
|
|---|
| 4723 | > ypos .95
|
|---|
| 4724 |
|
|---|
| 4725 | > 2dlabels text "2YSM WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 4726 |
|
|---|
| 4727 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2YSM--
|
|---|
| 4728 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 4729 | > true
|
|---|
| 4730 |
|
|---|
| 4731 | > select :UNL
|
|---|
| 4732 |
|
|---|
| 4733 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 4734 |
|
|---|
| 4735 | > view sel
|
|---|
| 4736 |
|
|---|
| 4737 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2YSM--
|
|---|
| 4738 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 4739 | > true
|
|---|
| 4740 |
|
|---|
| 4741 | > close
|
|---|
| 4742 |
|
|---|
| 4743 | > wait 5
|
|---|
| 4744 |
|
|---|
| 4745 | > set bgColor white
|
|---|
| 4746 |
|
|---|
| 4747 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/2LNK.pdbqt
|
|---|
| 4748 |
|
|---|
| 4749 | Chain information for 2LNK.pdbqt #1
|
|---|
| 4750 | ---
|
|---|
| 4751 | Chain | Description
|
|---|
| 4752 | A B | No description available
|
|---|
| 4753 | C | No description available
|
|---|
| 4754 |
|
|---|
| 4755 | Opened 2LNK.pdbqt containing 1 structures (3899 atoms, 3931 bonds)
|
|---|
| 4756 |
|
|---|
| 4757 | > wait 5
|
|---|
| 4758 |
|
|---|
| 4759 | > hide surfaces
|
|---|
| 4760 |
|
|---|
| 4761 | > hide atoms
|
|---|
| 4762 |
|
|---|
| 4763 | > show cartoons
|
|---|
| 4764 |
|
|---|
| 4765 | > wait 5
|
|---|
| 4766 |
|
|---|
| 4767 | > addh
|
|---|
| 4768 |
|
|---|
| 4769 | Summary of feedback from adding hydrogens to 2LNK.pdbqt #1
|
|---|
| 4770 | ---
|
|---|
| 4771 | notes | No usable SEQRES records for 2LNK.pdbqt (#1) chain A; guessing termini
|
|---|
| 4772 | instead
|
|---|
| 4773 | No usable SEQRES records for 2LNK.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 4774 | No usable SEQRES records for 2LNK.pdbqt (#1) chain C; guessing termini instead
|
|---|
| 4775 | Chain-initial residues that are actual N termini: /A MET 1, /B MET 1, /C GLN
|
|---|
| 4776 | 1897
|
|---|
| 4777 | Chain-initial residues that are not actual N termini:
|
|---|
| 4778 | Chain-final residues that are actual C termini: /A LYS 101, /B LYS 101, /C ALA
|
|---|
| 4779 | 1935
|
|---|
| 4780 | Chain-final residues that are not actual C termini:
|
|---|
| 4781 | 191 hydrogen bonds
|
|---|
| 4782 | 0 hydrogens added
|
|---|
| 4783 |
|
|---|
| 4784 |
|
|---|
| 4785 | > wait 5
|
|---|
| 4786 |
|
|---|
| 4787 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2LNK--
|
|---|
| 4788 | > WRM-16.result.pdbqt
|
|---|
| 4789 |
|
|---|
| 4790 | Summary of feedback from opening
|
|---|
| 4791 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2LNK--WRM-16.result.pdbqt
|
|---|
| 4792 | ---
|
|---|
| 4793 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 4794 | REMARK VINA RESULT: -7.0 0.000 0.000
|
|---|
| 4795 |
|
|---|
| 4796 | Ignored bad PDB record found on line 3
|
|---|
| 4797 | REMARK 5 active torsions:
|
|---|
| 4798 |
|
|---|
| 4799 | Ignored bad PDB record found on line 4
|
|---|
| 4800 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 4801 |
|
|---|
| 4802 | Ignored bad PDB record found on line 5
|
|---|
| 4803 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 4804 |
|
|---|
| 4805 | Ignored bad PDB record found on line 6
|
|---|
| 4806 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 4807 |
|
|---|
| 4808 | 184 messages similar to the above omitted
|
|---|
| 4809 |
|
|---|
| 4810 | Opened 2LNK--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 4811 | bonds)
|
|---|
| 4812 |
|
|---|
| 4813 | > wait 5
|
|---|
| 4814 |
|
|---|
| 4815 | > close #2.2-9
|
|---|
| 4816 |
|
|---|
| 4817 | > wait 5
|
|---|
| 4818 |
|
|---|
| 4819 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 4820 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2LNK--
|
|---|
| 4821 | > WRM-16.contacts.txt
|
|---|
| 4822 |
|
|---|
| 4823 |
|
|---|
| 4824 | Allowed overlap: -0.4
|
|---|
| 4825 | H-bond overlap reduction: 0.4
|
|---|
| 4826 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 4827 | Detect intra-residue contacts: False
|
|---|
| 4828 | Detect intra-molecule contacts: True
|
|---|
| 4829 |
|
|---|
| 4830 | 34 contacts
|
|---|
| 4831 | atom1 atom2 overlap distance
|
|---|
| 4832 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 72 HD2 0.362 2.518
|
|---|
| 4833 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 72 CD2 0.342 3.238
|
|---|
| 4834 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/A ASN 87 1HD2 0.261 2.349
|
|---|
| 4835 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/C THR 1906 2HG2 0.132 2.628
|
|---|
| 4836 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 72 HD2 0.076 2.534
|
|---|
| 4837 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 O 2LNK.pdbqt #1/A GLU 88 HB2 0.041 2.379
|
|---|
| 4838 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/A ASN 87 ND2 0.005 3.230
|
|---|
| 4839 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 72 HD2 -0.072 2.952
|
|---|
| 4840 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/A MET 84 SD -0.095 3.637
|
|---|
| 4841 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 O 2LNK.pdbqt #1/A MET 84 O -0.109 3.049
|
|---|
| 4842 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 O 2LNK.pdbqt #1/A ASN 87 ND2 -0.119 2.804
|
|---|
| 4843 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 O 2LNK.pdbqt #1/A ASN 87 1HD2 -0.126 2.146
|
|---|
| 4844 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/C THR 1906 CG2 -0.131 3.591
|
|---|
| 4845 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 27 CD1 -0.159 3.619
|
|---|
| 4846 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 O 2LNK.pdbqt #1/A ASN 87 1HD2 -0.162 2.222
|
|---|
| 4847 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 72 HD2 -0.219 2.829
|
|---|
| 4848 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 27 CD1 -0.222 3.682
|
|---|
| 4849 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 27 CZ -0.228 3.688
|
|---|
| 4850 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 O 2LNK.pdbqt #1/A GLU 88 CB -0.228 3.348
|
|---|
| 4851 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 72 CD2 -0.254 3.564
|
|---|
| 4852 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 72 CE2 -0.261 3.841
|
|---|
| 4853 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/A MET 84 HB3 -0.283 3.043
|
|---|
| 4854 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/A MET 84 SD -0.288 3.830
|
|---|
| 4855 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/A ASN 87 ND2 -0.291 3.796
|
|---|
| 4856 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 27 CE1 -0.298 3.608
|
|---|
| 4857 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 72 CD2 -0.300 3.880
|
|---|
| 4858 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 27 CE1 -0.300 3.760
|
|---|
| 4859 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 27 CE1 -0.318 3.778
|
|---|
| 4860 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 72 HD2 -0.356 2.966
|
|---|
| 4861 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 O 2LNK.pdbqt #1/B PHE 27 CD2 -0.368 3.488
|
|---|
| 4862 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 27 CG -0.376 3.836
|
|---|
| 4863 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/B PHE 27 CE2 -0.386 3.846
|
|---|
| 4864 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/A MET 84 SD -0.386 3.928
|
|---|
| 4865 | 2LNK--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LNK.pdbqt #1/A ASN 87 ND2 -0.390 3.895
|
|---|
| 4866 |
|
|---|
| 4867 |
|
|---|
| 4868 |
|
|---|
| 4869 | 34 contacts
|
|---|
| 4870 |
|
|---|
| 4871 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 4872 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2LNK--
|
|---|
| 4873 | > WRM-16.hbonds.txt
|
|---|
| 4874 |
|
|---|
| 4875 |
|
|---|
| 4876 | Finding intermodel H-bonds
|
|---|
| 4877 | Finding intramodel H-bonds
|
|---|
| 4878 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 4879 | Models used:
|
|---|
| 4880 | 1 2LNK.pdbqt
|
|---|
| 4881 | 2.1 2LNK--WRM-16.result.pdbqt
|
|---|
| 4882 |
|
|---|
| 4883 | 0 H-bonds
|
|---|
| 4884 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 4885 |
|
|---|
| 4886 |
|
|---|
| 4887 |
|
|---|
| 4888 | 0 hydrogen bonds found
|
|---|
| 4889 |
|
|---|
| 4890 | > select :UNL
|
|---|
| 4891 |
|
|---|
| 4892 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 4893 |
|
|---|
| 4894 | > label sel text "Ligand "
|
|---|
| 4895 |
|
|---|
| 4896 | > label height 1
|
|---|
| 4897 |
|
|---|
| 4898 | > ~select
|
|---|
| 4899 |
|
|---|
| 4900 | Nothing selected
|
|---|
| 4901 |
|
|---|
| 4902 | > 2dlabels text "Binding Energy: -7.0 kcal/mol" color red size 18 xpos .03
|
|---|
| 4903 | > ypos .95
|
|---|
| 4904 |
|
|---|
| 4905 | > 2dlabels text "2LNK WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 4906 |
|
|---|
| 4907 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2LNK--
|
|---|
| 4908 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 4909 | > true
|
|---|
| 4910 |
|
|---|
| 4911 | > select :UNL
|
|---|
| 4912 |
|
|---|
| 4913 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 4914 |
|
|---|
| 4915 | > view sel
|
|---|
| 4916 |
|
|---|
| 4917 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2LNK--
|
|---|
| 4918 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 4919 | > true
|
|---|
| 4920 |
|
|---|
| 4921 | > close
|
|---|
| 4922 |
|
|---|
| 4923 | > wait 5
|
|---|
| 4924 |
|
|---|
| 4925 | > set bgColor white
|
|---|
| 4926 |
|
|---|
| 4927 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1XUM.pdbqt
|
|---|
| 4928 |
|
|---|
| 4929 | Chain information for 1XUM.pdbqt #1
|
|---|
| 4930 | ---
|
|---|
| 4931 | Chain | Description
|
|---|
| 4932 | A | No description available
|
|---|
| 4933 |
|
|---|
| 4934 | Opened 1XUM.pdbqt containing 1 structures (2876 atoms, 2908 bonds)
|
|---|
| 4935 |
|
|---|
| 4936 | > wait 5
|
|---|
| 4937 |
|
|---|
| 4938 | > hide surfaces
|
|---|
| 4939 |
|
|---|
| 4940 | > hide atoms
|
|---|
| 4941 |
|
|---|
| 4942 | > show cartoons
|
|---|
| 4943 |
|
|---|
| 4944 | > wait 5
|
|---|
| 4945 |
|
|---|
| 4946 | > addh
|
|---|
| 4947 |
|
|---|
| 4948 | Summary of feedback from adding hydrogens to 1XUM.pdbqt #1
|
|---|
| 4949 | ---
|
|---|
| 4950 | notes | No usable SEQRES records for 1XUM.pdbqt (#1) chain A; guessing termini
|
|---|
| 4951 | instead
|
|---|
| 4952 | Chain-initial residues that are actual N termini: /A THR 54
|
|---|
| 4953 | Chain-initial residues that are not actual N termini:
|
|---|
| 4954 | Chain-final residues that are actual C termini: /A THR 236
|
|---|
| 4955 | Chain-final residues that are not actual C termini:
|
|---|
| 4956 | 96 hydrogen bonds
|
|---|
| 4957 | 59 hydrogens added
|
|---|
| 4958 |
|
|---|
| 4959 |
|
|---|
| 4960 | > wait 5
|
|---|
| 4961 |
|
|---|
| 4962 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1XUM--
|
|---|
| 4963 | > WRM-16.result.pdbqt
|
|---|
| 4964 |
|
|---|
| 4965 | Summary of feedback from opening
|
|---|
| 4966 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1XUM--WRM-16.result.pdbqt
|
|---|
| 4967 | ---
|
|---|
| 4968 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 4969 | REMARK VINA RESULT: -7.8 0.000 0.000
|
|---|
| 4970 |
|
|---|
| 4971 | Ignored bad PDB record found on line 3
|
|---|
| 4972 | REMARK 5 active torsions:
|
|---|
| 4973 |
|
|---|
| 4974 | Ignored bad PDB record found on line 4
|
|---|
| 4975 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 4976 |
|
|---|
| 4977 | Ignored bad PDB record found on line 5
|
|---|
| 4978 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 4979 |
|
|---|
| 4980 | Ignored bad PDB record found on line 6
|
|---|
| 4981 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 4982 |
|
|---|
| 4983 | 184 messages similar to the above omitted
|
|---|
| 4984 |
|
|---|
| 4985 | Opened 1XUM--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 4986 | bonds)
|
|---|
| 4987 |
|
|---|
| 4988 | > wait 5
|
|---|
| 4989 |
|
|---|
| 4990 | > close #2.2-9
|
|---|
| 4991 |
|
|---|
| 4992 | > wait 5
|
|---|
| 4993 |
|
|---|
| 4994 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 4995 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1XUM--
|
|---|
| 4996 | > WRM-16.contacts.txt
|
|---|
| 4997 |
|
|---|
| 4998 |
|
|---|
| 4999 | Allowed overlap: -0.4
|
|---|
| 5000 | H-bond overlap reduction: 0.4
|
|---|
| 5001 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 5002 | Detect intra-residue contacts: False
|
|---|
| 5003 | Detect intra-molecule contacts: True
|
|---|
| 5004 |
|
|---|
| 5005 | 50 contacts
|
|---|
| 5006 | atom1 atom2 overlap distance
|
|---|
| 5007 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A LYS 183 HD2 0.493 2.387
|
|---|
| 5008 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A THR 159 HG1 0.216 2.664
|
|---|
| 5009 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A LYS 183 CD 0.190 3.390
|
|---|
| 5010 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A TYR 206 CE2 0.101 3.359
|
|---|
| 5011 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A SER 134 HG 0.100 2.660
|
|---|
| 5012 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A LYS 183 HZ2 0.069 2.691
|
|---|
| 5013 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XUM.pdbqt #1/A LYS 209 CD 0.018 3.102
|
|---|
| 5014 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XUM.pdbqt #1/A LYS 209 CE 0.016 3.104
|
|---|
| 5015 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A ARG 109 2HH1 -0.001 2.761
|
|---|
| 5016 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XUM.pdbqt #1/A LYS 209 HD2 -0.002 2.422
|
|---|
| 5017 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XUM.pdbqt #1/A ASP 160 OD2 -0.014 2.914
|
|---|
| 5018 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A TYR 185 CB -0.062 3.372
|
|---|
| 5019 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A THR 159 HG1 -0.100 2.980
|
|---|
| 5020 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A THR 159 OG1 -0.102 3.482
|
|---|
| 5021 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A ASN 110 2HD2 -0.109 2.869
|
|---|
| 5022 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A GLU 157 OE1 -0.125 3.485
|
|---|
| 5023 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A ARG 109 2HH1 -0.126 2.886
|
|---|
| 5024 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A ARG 109 HD2 -0.128 2.888
|
|---|
| 5025 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A LYS 183 NZ -0.138 3.523
|
|---|
| 5026 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A TYR 206 HE2 -0.140 2.900
|
|---|
| 5027 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A TYR 206 CD2 -0.142 3.602
|
|---|
| 5028 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A TYR 185 HB2 -0.156 2.766
|
|---|
| 5029 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A GLU 157 CD -0.190 3.770
|
|---|
| 5030 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XUM.pdbqt #1/A TYR 185 HB2 -0.198 2.618
|
|---|
| 5031 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XUM.pdbqt #1/A TYR 185 CD2 -0.208 3.368
|
|---|
| 5032 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XUM.pdbqt #1/A LYS 209 HE1 -0.225 2.645
|
|---|
| 5033 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A ARG 109 HD2 -0.234 2.994
|
|---|
| 5034 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A ARG 109 CD -0.246 3.706
|
|---|
| 5035 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A ARG 109 NH1 -0.257 3.762
|
|---|
| 5036 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A SER 134 OG -0.264 3.524
|
|---|
| 5037 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A TYR 206 CD2 -0.267 3.727
|
|---|
| 5038 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A ASN 110 ND2 -0.276 3.661
|
|---|
| 5039 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A THR 159 1HG2 -0.283 3.163
|
|---|
| 5040 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A ARG 109 2HH1 -0.289 2.899
|
|---|
| 5041 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XUM.pdbqt #1/A ASP 160 CG -0.294 3.414
|
|---|
| 5042 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A ASN 186 ND2 -0.305 3.540
|
|---|
| 5043 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A ARG 109 NH1 -0.309 3.694
|
|---|
| 5044 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XUM.pdbqt #1/A TYR 185 CE2 -0.315 3.475
|
|---|
| 5045 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XUM.pdbqt #1/A THR 159 OG1 -0.321 2.841
|
|---|
| 5046 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A ARG 109 NH1 -0.331 3.716
|
|---|
| 5047 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A ARG 109 NH1 -0.334 3.719
|
|---|
| 5048 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A TYR 185 CG -0.343 3.653
|
|---|
| 5049 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A THR 159 CG2 -0.352 3.932
|
|---|
| 5050 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A ARG 109 NH1 -0.358 3.743
|
|---|
| 5051 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XUM.pdbqt #1/A THR 159 HG1 -0.360 2.380
|
|---|
| 5052 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A TYR 206 CE2 -0.371 3.831
|
|---|
| 5053 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A SER 234 HG -0.378 3.258
|
|---|
| 5054 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A LYS 183 CE -0.381 3.841
|
|---|
| 5055 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A THR 159 OG1 -0.387 3.767
|
|---|
| 5056 | 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 C 1XUM.pdbqt #1/A ARG 109 2HH1 -0.390 3.150
|
|---|
| 5057 |
|
|---|
| 5058 |
|
|---|
| 5059 |
|
|---|
| 5060 | 50 contacts
|
|---|
| 5061 |
|
|---|
| 5062 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 5063 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1XUM--
|
|---|
| 5064 | > WRM-16.hbonds.txt
|
|---|
| 5065 |
|
|---|
| 5066 |
|
|---|
| 5067 | Finding intermodel H-bonds
|
|---|
| 5068 | Finding intramodel H-bonds
|
|---|
| 5069 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 5070 | Models used:
|
|---|
| 5071 | 1 1XUM.pdbqt
|
|---|
| 5072 | 2.1 1XUM--WRM-16.result.pdbqt
|
|---|
| 5073 |
|
|---|
| 5074 | 2 H-bonds
|
|---|
| 5075 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 5076 | 1XUM.pdbqt #1/A ASN 186 ND2 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XUM.pdbqt #1/A ASN 186 1HD2 3.170 2.565
|
|---|
| 5077 | 1XUM.pdbqt #1/A ASN 208 ND2 1XUM--WRM-16.result.pdbqt #2.1/? UNL 1 O 1XUM.pdbqt #1/A ASN 208 2HD2 3.318 2.547
|
|---|
| 5078 |
|
|---|
| 5079 |
|
|---|
| 5080 |
|
|---|
| 5081 | 2 hydrogen bonds found
|
|---|
| 5082 |
|
|---|
| 5083 | > select :UNL
|
|---|
| 5084 |
|
|---|
| 5085 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 5086 |
|
|---|
| 5087 | > label sel text "Ligand "
|
|---|
| 5088 |
|
|---|
| 5089 | > label height 1
|
|---|
| 5090 |
|
|---|
| 5091 | > ~select
|
|---|
| 5092 |
|
|---|
| 5093 | Nothing selected
|
|---|
| 5094 |
|
|---|
| 5095 | > 2dlabels text "Binding Energy: -7.8 kcal/mol" color red size 18 xpos .03
|
|---|
| 5096 | > ypos .95
|
|---|
| 5097 |
|
|---|
| 5098 | > 2dlabels text "1XUM WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 5099 |
|
|---|
| 5100 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1XUM--
|
|---|
| 5101 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 5102 | > true
|
|---|
| 5103 |
|
|---|
| 5104 | > select :UNL
|
|---|
| 5105 |
|
|---|
| 5106 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 5107 |
|
|---|
| 5108 | > view sel
|
|---|
| 5109 |
|
|---|
| 5110 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1XUM--
|
|---|
| 5111 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 5112 | > true
|
|---|
| 5113 |
|
|---|
| 5114 | > close
|
|---|
| 5115 |
|
|---|
| 5116 | > wait 5
|
|---|
| 5117 |
|
|---|
| 5118 | > set bgColor white
|
|---|
| 5119 |
|
|---|
| 5120 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/6LTH.pdbqt
|
|---|
| 5121 |
|
|---|
| 5122 | Chain information for 6LTH.pdbqt #1
|
|---|
| 5123 | ---
|
|---|
| 5124 | Chain | Description
|
|---|
| 5125 | I | No description available
|
|---|
| 5126 | L | No description available
|
|---|
| 5127 | M | No description available
|
|---|
| 5128 | N | No description available
|
|---|
| 5129 | O | No description available
|
|---|
| 5130 | P | No description available
|
|---|
| 5131 | Q | No description available
|
|---|
| 5132 | R | No description available
|
|---|
| 5133 |
|
|---|
| 5134 | Opened 6LTH.pdbqt containing 1 structures (30136 atoms, 30416 bonds)
|
|---|
| 5135 |
|
|---|
| 5136 | > wait 5
|
|---|
| 5137 |
|
|---|
| 5138 | > hide surfaces
|
|---|
| 5139 |
|
|---|
| 5140 | > hide atoms
|
|---|
| 5141 |
|
|---|
| 5142 | > show cartoons
|
|---|
| 5143 |
|
|---|
| 5144 | > wait 5
|
|---|
| 5145 |
|
|---|
| 5146 | > addh
|
|---|
| 5147 |
|
|---|
| 5148 | Summary of feedback from adding hydrogens to 6LTH.pdbqt #1
|
|---|
| 5149 | ---
|
|---|
| 5150 | warnings | Not adding hydrogens to /M LYS 199 CD because it is missing heavy-
|
|---|
| 5151 | atom bond partners
|
|---|
| 5152 | Not adding hydrogens to /M LYS 211 CG because it is missing heavy-atom bond
|
|---|
| 5153 | partners
|
|---|
| 5154 | notes | No usable SEQRES records for 6LTH.pdbqt (#1) chain I; guessing termini
|
|---|
| 5155 | instead
|
|---|
| 5156 | No usable SEQRES records for 6LTH.pdbqt (#1) chain L; guessing termini instead
|
|---|
| 5157 | No usable SEQRES records for 6LTH.pdbqt (#1) chain M; guessing termini instead
|
|---|
| 5158 | No usable SEQRES records for 6LTH.pdbqt (#1) chain N; guessing termini instead
|
|---|
| 5159 | No usable SEQRES records for 6LTH.pdbqt (#1) chain O; guessing termini instead
|
|---|
| 5160 | 3 messages similar to the above omitted
|
|---|
| 5161 | Chain-initial residues that are actual N termini: /I SER 350, /L ILE 1639, /M
|
|---|
| 5162 | SER 7, /N HIS 423, /O HIS 423, /P LYS 125, /Q SER 172, /R GLY 13
|
|---|
| 5163 | Chain-initial residues that are not actual N termini: /I LEU 396, /L GLU 1802,
|
|---|
| 5164 | /L ILE 1954, /L GLU 2047, /L PRO 2225, /M ASP 78, /M ASP 172, /M GLN 257, /M
|
|---|
| 5165 | PRO 332, /N THR 602, /N ASN 671, /N LEU 858, /O THR 598, /O LEU 656, /O ALA
|
|---|
| 5166 | 867, /P GLN 291, /P THR 399
|
|---|
| 5167 | Chain-final residues that are actual C termini: /I LEU 476, /L SER 2285, /M
|
|---|
| 5168 | THR 357, /N GLN 952, /O GLN 952, /P GLU 505, /Q LEU 276, /R LYS 82
|
|---|
| 5169 | Chain-final residues that are not actual C termini: /I LEU 388, /L ASP 1746,
|
|---|
| 5170 | /L LYS 1862, /L LYS 2025, /L GLN 2210, /M SER 67, /M ASP 101, /M PRO 249, /M
|
|---|
| 5171 | TYR 326, /N ASP 515, /N ARG 641, /N MET 703, /O GLN 545, /O ASP 651, /O ARG
|
|---|
| 5172 | 717, /P LYS 177, /P GLU 369
|
|---|
| 5173 | 1386 hydrogen bonds
|
|---|
| 5174 | Adding 'H' to /I LEU 396
|
|---|
| 5175 | Adding 'H' to /L GLU 1802
|
|---|
| 5176 | Adding 'H' to /L ILE 1954
|
|---|
| 5177 | Adding 'H' to /L GLU 2047
|
|---|
| 5178 | Adding 'H' to /M ASP 78
|
|---|
| 5179 | 10 messages similar to the above omitted
|
|---|
| 5180 | /I LEU 388 is not terminus, removing H atom from 'C'
|
|---|
| 5181 | /L ASP 1746 is not terminus, removing H atom from 'C'
|
|---|
| 5182 | /L LYS 1862 is not terminus, removing H atom from 'C'
|
|---|
| 5183 | /L LYS 2025 is not terminus, removing H atom from 'C'
|
|---|
| 5184 | /L GLN 2210 is not terminus, removing H atom from 'C'
|
|---|
| 5185 | 12 messages similar to the above omitted
|
|---|
| 5186 | -24 hydrogens added
|
|---|
| 5187 |
|
|---|
| 5188 |
|
|---|
| 5189 | > wait 5
|
|---|
| 5190 |
|
|---|
| 5191 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/6LTH--
|
|---|
| 5192 | > WRM-16.result.pdbqt
|
|---|
| 5193 |
|
|---|
| 5194 | Summary of feedback from opening
|
|---|
| 5195 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/6LTH--WRM-16.result.pdbqt
|
|---|
| 5196 | ---
|
|---|
| 5197 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 5198 | REMARK VINA RESULT: -8.3 0.000 0.000
|
|---|
| 5199 |
|
|---|
| 5200 | Ignored bad PDB record found on line 3
|
|---|
| 5201 | REMARK 5 active torsions:
|
|---|
| 5202 |
|
|---|
| 5203 | Ignored bad PDB record found on line 4
|
|---|
| 5204 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 5205 |
|
|---|
| 5206 | Ignored bad PDB record found on line 5
|
|---|
| 5207 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 5208 |
|
|---|
| 5209 | Ignored bad PDB record found on line 6
|
|---|
| 5210 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 5211 |
|
|---|
| 5212 | 184 messages similar to the above omitted
|
|---|
| 5213 |
|
|---|
| 5214 | Opened 6LTH--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 5215 | bonds)
|
|---|
| 5216 |
|
|---|
| 5217 | > wait 5
|
|---|
| 5218 |
|
|---|
| 5219 | > close #2.2-9
|
|---|
| 5220 |
|
|---|
| 5221 | > wait 5
|
|---|
| 5222 |
|
|---|
| 5223 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 5224 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/6LTH--
|
|---|
| 5225 | > WRM-16.contacts.txt
|
|---|
| 5226 |
|
|---|
| 5227 |
|
|---|
| 5228 | Allowed overlap: -0.4
|
|---|
| 5229 | H-bond overlap reduction: 0.4
|
|---|
| 5230 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 5231 | Detect intra-residue contacts: False
|
|---|
| 5232 | Detect intra-molecule contacts: True
|
|---|
| 5233 |
|
|---|
| 5234 | 48 contacts
|
|---|
| 5235 | atom1 atom2 overlap distance
|
|---|
| 5236 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/I LYS 461 HG1 0.557 2.203
|
|---|
| 5237 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/I LYS 461 CG 0.147 3.313
|
|---|
| 5238 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L PRO 2075 HG2 0.113 2.647
|
|---|
| 5239 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 O 6LTH.pdbqt #1/L PHE 1999 HE1 0.078 2.342
|
|---|
| 5240 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/I LYS 461 HG1 0.071 2.689
|
|---|
| 5241 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L TYR 2076 OH 0.045 3.215
|
|---|
| 5242 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 O 6LTH.pdbqt #1/L GLN 2070 HA 0.021 2.399
|
|---|
| 5243 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/I LYS 461 HA 0.009 2.871
|
|---|
| 5244 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LTH.pdbqt #1/L TYR 2076 CE1 0.003 3.577
|
|---|
| 5245 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/I LYS 461 CA 0.002 3.578
|
|---|
| 5246 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/I GLN 464 HG2 -0.053 2.813
|
|---|
| 5247 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L LYS 2003 HG2 -0.064 2.824
|
|---|
| 5248 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LTH.pdbqt #1/L TYR 2076 CZ -0.085 3.665
|
|---|
| 5249 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LTH.pdbqt #1/L PRO 2075 HB1 -0.087 2.967
|
|---|
| 5250 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/I GLN 464 CG -0.091 3.551
|
|---|
| 5251 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LTH.pdbqt #1/L TYR 2076 OH -0.096 3.476
|
|---|
| 5252 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L LYS 2003 HG2 -0.114 2.874
|
|---|
| 5253 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L ASP 2072 HB1 -0.134 3.014
|
|---|
| 5254 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L LYS 2003 HG2 -0.135 2.895
|
|---|
| 5255 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/I LYS 461 CB -0.137 3.717
|
|---|
| 5256 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L PRO 2075 HG2 -0.165 2.775
|
|---|
| 5257 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/I GLN 464 HG2 -0.175 2.785
|
|---|
| 5258 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 O 6LTH.pdbqt #1/L GLN 2128 CD -0.176 3.336
|
|---|
| 5259 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L LYS 2003 HG2 -0.189 2.949
|
|---|
| 5260 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/I GLN 464 HB2 -0.190 2.950
|
|---|
| 5261 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LTH.pdbqt #1/L PRO 2075 CB -0.197 3.777
|
|---|
| 5262 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/I LYS 461 HB2 -0.207 3.087
|
|---|
| 5263 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L GLN 2128 OE1 -0.214 3.304
|
|---|
| 5264 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L LYS 2003 HG2 -0.215 2.825
|
|---|
| 5265 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L PRO 2075 CG -0.225 3.685
|
|---|
| 5266 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 O 6LTH.pdbqt #1/L GLN 2070 CA -0.232 3.352
|
|---|
| 5267 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L PHE 1999 HE1 -0.235 2.845
|
|---|
| 5268 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 O 6LTH.pdbqt #1/L GLN 2070 CD -0.238 3.358
|
|---|
| 5269 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/I GLN 464 CG -0.240 3.700
|
|---|
| 5270 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/I LYS 461 N -0.245 3.750
|
|---|
| 5271 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L ASP 2072 CB -0.251 3.831
|
|---|
| 5272 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 O 6LTH.pdbqt #1/L PHE 1999 CE1 -0.258 3.378
|
|---|
| 5273 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/I LYS 461 CG -0.263 3.723
|
|---|
| 5274 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L TYR 2076 CZ -0.264 3.724
|
|---|
| 5275 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L TYR 2076 HH -0.283 3.043
|
|---|
| 5276 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L GLN 2128 2HE2 -0.292 2.902
|
|---|
| 5277 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L PHE 1999 HE1 -0.313 3.193
|
|---|
| 5278 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L LYS 2003 CG -0.322 3.782
|
|---|
| 5279 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L GLN 2070 NE2 -0.333 3.568
|
|---|
| 5280 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L LYS 2003 HG2 -0.349 2.959
|
|---|
| 5281 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/I GLU 465 HG2 -0.380 3.140
|
|---|
| 5282 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 O 6LTH.pdbqt #1/L GLN 2128 OE1 -0.393 3.333
|
|---|
| 5283 | 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LTH.pdbqt #1/L LYS 2003 CG -0.397 3.857
|
|---|
| 5284 |
|
|---|
| 5285 |
|
|---|
| 5286 |
|
|---|
| 5287 | 48 contacts
|
|---|
| 5288 |
|
|---|
| 5289 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 5290 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/6LTH--
|
|---|
| 5291 | > WRM-16.hbonds.txt
|
|---|
| 5292 |
|
|---|
| 5293 |
|
|---|
| 5294 | Finding intermodel H-bonds
|
|---|
| 5295 | Finding intramodel H-bonds
|
|---|
| 5296 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 5297 | Models used:
|
|---|
| 5298 | 1 6LTH.pdbqt
|
|---|
| 5299 | 2.1 6LTH--WRM-16.result.pdbqt
|
|---|
| 5300 |
|
|---|
| 5301 | 1 H-bonds
|
|---|
| 5302 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 5303 | 6LTH.pdbqt #1/L GLN 2128 NE2 6LTH--WRM-16.result.pdbqt #2.1/? UNL 1 O 6LTH.pdbqt #1/L GLN 2128 2HE2 3.227 2.606
|
|---|
| 5304 |
|
|---|
| 5305 |
|
|---|
| 5306 |
|
|---|
| 5307 | 1 hydrogen bonds found
|
|---|
| 5308 |
|
|---|
| 5309 | > select :UNL
|
|---|
| 5310 |
|
|---|
| 5311 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 5312 |
|
|---|
| 5313 | > label sel text "Ligand "
|
|---|
| 5314 |
|
|---|
| 5315 | > label height 1
|
|---|
| 5316 |
|
|---|
| 5317 | > ~select
|
|---|
| 5318 |
|
|---|
| 5319 | Nothing selected
|
|---|
| 5320 |
|
|---|
| 5321 | > 2dlabels text "Binding Energy: -8.3 kcal/mol" color red size 18 xpos .03
|
|---|
| 5322 | > ypos .95
|
|---|
| 5323 |
|
|---|
| 5324 | > 2dlabels text "6LTH WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 5325 |
|
|---|
| 5326 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/6LTH--
|
|---|
| 5327 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 5328 | > true
|
|---|
| 5329 |
|
|---|
| 5330 | > select :UNL
|
|---|
| 5331 |
|
|---|
| 5332 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 5333 |
|
|---|
| 5334 | > view sel
|
|---|
| 5335 |
|
|---|
| 5336 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/6LTH--
|
|---|
| 5337 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 5338 | > true
|
|---|
| 5339 |
|
|---|
| 5340 | > close
|
|---|
| 5341 |
|
|---|
| 5342 | > wait 5
|
|---|
| 5343 |
|
|---|
| 5344 | > set bgColor white
|
|---|
| 5345 |
|
|---|
| 5346 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/3H9R.pdbqt
|
|---|
| 5347 |
|
|---|
| 5348 | Chain information for 3H9R.pdbqt #1
|
|---|
| 5349 | ---
|
|---|
| 5350 | Chain | Description
|
|---|
| 5351 | A | No description available
|
|---|
| 5352 | B | No description available
|
|---|
| 5353 |
|
|---|
| 5354 | Opened 3H9R.pdbqt containing 1 structures (6620 atoms, 6691 bonds)
|
|---|
| 5355 |
|
|---|
| 5356 | > wait 5
|
|---|
| 5357 |
|
|---|
| 5358 | > hide surfaces
|
|---|
| 5359 |
|
|---|
| 5360 | > hide atoms
|
|---|
| 5361 |
|
|---|
| 5362 | > show cartoons
|
|---|
| 5363 |
|
|---|
| 5364 | > wait 5
|
|---|
| 5365 |
|
|---|
| 5366 | > addh
|
|---|
| 5367 |
|
|---|
| 5368 | Summary of feedback from adding hydrogens to 3H9R.pdbqt #1
|
|---|
| 5369 | ---
|
|---|
| 5370 | warnings | Not adding hydrogens to /A ARG 218 CD because it is missing heavy-
|
|---|
| 5371 | atom bond partners
|
|---|
| 5372 | Not adding hydrogens to /A SER 276 CB because it is missing heavy-atom bond
|
|---|
| 5373 | partners
|
|---|
| 5374 | Not adding hydrogens to /A ASP 499 CB because it is missing heavy-atom bond
|
|---|
| 5375 | partners
|
|---|
| 5376 | Not adding hydrogens to /B ARG 14 CB because it is missing heavy-atom bond
|
|---|
| 5377 | partners
|
|---|
| 5378 | notes | No usable SEQRES records for 3H9R.pdbqt (#1) chain A; guessing termini
|
|---|
| 5379 | instead
|
|---|
| 5380 | No usable SEQRES records for 3H9R.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 5381 | Chain-initial residues that are actual N termini: /A THR 172, /B GLY 2
|
|---|
| 5382 | Chain-initial residues that are not actual N termini: /A SER 276, /A ARG 375
|
|---|
| 5383 | Chain-final residues that are actual C termini: /A ASP 499, /B GLU 108
|
|---|
| 5384 | Chain-final residues that are not actual C termini: /A SER 272, /A HIS 361
|
|---|
| 5385 | 360 hydrogen bonds
|
|---|
| 5386 | Adding 'H' to /A SER 276
|
|---|
| 5387 | Adding 'H' to /A ARG 375
|
|---|
| 5388 | /A SER 272 is not terminus, removing H atom from 'C'
|
|---|
| 5389 | /A HIS 361 is not terminus, removing H atom from 'C'
|
|---|
| 5390 | 7 hydrogens added
|
|---|
| 5391 |
|
|---|
| 5392 |
|
|---|
| 5393 | > wait 5
|
|---|
| 5394 |
|
|---|
| 5395 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/3H9R--
|
|---|
| 5396 | > WRM-16.result.pdbqt
|
|---|
| 5397 |
|
|---|
| 5398 | Summary of feedback from opening
|
|---|
| 5399 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/3H9R--WRM-16.result.pdbqt
|
|---|
| 5400 | ---
|
|---|
| 5401 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 5402 | REMARK VINA RESULT: -10.1 0.000 0.000
|
|---|
| 5403 |
|
|---|
| 5404 | Ignored bad PDB record found on line 3
|
|---|
| 5405 | REMARK 5 active torsions:
|
|---|
| 5406 |
|
|---|
| 5407 | Ignored bad PDB record found on line 4
|
|---|
| 5408 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 5409 |
|
|---|
| 5410 | Ignored bad PDB record found on line 5
|
|---|
| 5411 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 5412 |
|
|---|
| 5413 | Ignored bad PDB record found on line 6
|
|---|
| 5414 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 5415 |
|
|---|
| 5416 | 184 messages similar to the above omitted
|
|---|
| 5417 |
|
|---|
| 5418 | Opened 3H9R--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 5419 | bonds)
|
|---|
| 5420 |
|
|---|
| 5421 | > wait 5
|
|---|
| 5422 |
|
|---|
| 5423 | > close #2.2-9
|
|---|
| 5424 |
|
|---|
| 5425 | > wait 5
|
|---|
| 5426 |
|
|---|
| 5427 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 5428 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3H9R--
|
|---|
| 5429 | > WRM-16.contacts.txt
|
|---|
| 5430 |
|
|---|
| 5431 |
|
|---|
| 5432 | Allowed overlap: -0.4
|
|---|
| 5433 | H-bond overlap reduction: 0.4
|
|---|
| 5434 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 5435 | Detect intra-residue contacts: False
|
|---|
| 5436 | Detect intra-molecule contacts: True
|
|---|
| 5437 |
|
|---|
| 5438 | 56 contacts
|
|---|
| 5439 | atom1 atom2 overlap distance
|
|---|
| 5440 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A GLY 215 HA2 0.237 2.643
|
|---|
| 5441 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3H9R.pdbqt #1/A LYS 340 HE1 0.199 2.681
|
|---|
| 5442 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A SER 290 HG 0.131 2.629
|
|---|
| 5443 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LYS 340 HG1 0.091 2.669
|
|---|
| 5444 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A TYR 219 OH 0.084 3.296
|
|---|
| 5445 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A VAL 222 2HG1 0.026 2.734
|
|---|
| 5446 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LEU 343 3HD2 -0.001 2.611
|
|---|
| 5447 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A ALA 233 CB -0.040 3.500
|
|---|
| 5448 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LYS 340 HE1 -0.051 2.811
|
|---|
| 5449 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LYS 340 HE1 -0.053 2.663
|
|---|
| 5450 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A GLY 215 CA -0.076 3.656
|
|---|
| 5451 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LEU 343 2HD1 -0.077 2.687
|
|---|
| 5452 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LYS 340 O -0.104 3.344
|
|---|
| 5453 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A TYR 219 HH -0.112 2.992
|
|---|
| 5454 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A VAL 214 1HG2 -0.136 2.896
|
|---|
| 5455 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LYS 340 O -0.146 3.506
|
|---|
| 5456 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A TYR 219 HH -0.154 2.914
|
|---|
| 5457 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A VAL 222 2HG1 -0.157 2.767
|
|---|
| 5458 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LEU 343 3HD2 -0.158 2.768
|
|---|
| 5459 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3H9R.pdbqt #1/A ASP 293 OD2 -0.168 3.528
|
|---|
| 5460 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A TYR 219 CZ -0.169 3.749
|
|---|
| 5461 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A VAL 214 CG2 -0.171 3.631
|
|---|
| 5462 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A TYR 285 CD1 -0.171 3.631
|
|---|
| 5463 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A SER 290 OG -0.174 3.434
|
|---|
| 5464 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LYS 340 CE -0.180 3.640
|
|---|
| 5465 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LEU 343 3HD2 -0.205 2.815
|
|---|
| 5466 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3H9R.pdbqt #1/A LYS 340 CE -0.206 3.786
|
|---|
| 5467 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A TYR 219 HE2 -0.256 3.016
|
|---|
| 5468 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A TYR 219 CE2 -0.259 3.839
|
|---|
| 5469 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LYS 340 CG -0.261 3.721
|
|---|
| 5470 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 O 3H9R.pdbqt #1/A LEU 343 2HD1 -0.276 2.736
|
|---|
| 5471 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LEU 343 CD2 -0.279 3.589
|
|---|
| 5472 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 O 3H9R.pdbqt #1/A ALA 353 HB1 -0.284 2.704
|
|---|
| 5473 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LYS 340 HG1 -0.287 3.047
|
|---|
| 5474 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LYS 340 HG1 -0.287 2.897
|
|---|
| 5475 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A ALA 233 HB1 -0.289 3.049
|
|---|
| 5476 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A ALA 233 HB2 -0.297 3.177
|
|---|
| 5477 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A ALA 233 HB1 -0.298 3.058
|
|---|
| 5478 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LEU 343 CD2 -0.307 3.617
|
|---|
| 5479 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3H9R.pdbqt #1/A TYR 292 CD2 -0.308 3.888
|
|---|
| 5480 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A VAL 222 3HG2 -0.317 2.927
|
|---|
| 5481 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A ALA 233 HB2 -0.319 3.079
|
|---|
| 5482 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A TYR 285 CE1 -0.325 3.785
|
|---|
| 5483 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3H9R.pdbqt #1/A TYR 292 HD2 -0.326 3.206
|
|---|
| 5484 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A ALA 233 CB -0.326 3.786
|
|---|
| 5485 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A VAL 222 2HG1 -0.350 3.110
|
|---|
| 5486 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A VAL 222 CG1 -0.350 3.810
|
|---|
| 5487 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A TYR 219 CE2 -0.367 3.677
|
|---|
| 5488 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LYS 340 CE -0.368 3.678
|
|---|
| 5489 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A TYR 219 HE2 -0.371 2.981
|
|---|
| 5490 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LYS 340 O -0.374 3.464
|
|---|
| 5491 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A ALA 233 CB -0.376 3.956
|
|---|
| 5492 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A LEU 263 1HD2 -0.382 3.262
|
|---|
| 5493 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 O 3H9R.pdbqt #1/A LEU 263 CD2 -0.384 3.544
|
|---|
| 5494 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A TYR 285 HD1 -0.388 3.148
|
|---|
| 5495 | 3H9R--WRM-16.result.pdbqt #2.1/? UNL 1 C 3H9R.pdbqt #1/A VAL 222 CG1 -0.390 3.970
|
|---|
| 5496 |
|
|---|
| 5497 |
|
|---|
| 5498 |
|
|---|
| 5499 | 56 contacts
|
|---|
| 5500 |
|
|---|
| 5501 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 5502 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3H9R--
|
|---|
| 5503 | > WRM-16.hbonds.txt
|
|---|
| 5504 |
|
|---|
| 5505 |
|
|---|
| 5506 | Finding intermodel H-bonds
|
|---|
| 5507 | Finding intramodel H-bonds
|
|---|
| 5508 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 5509 | Models used:
|
|---|
| 5510 | 1 3H9R.pdbqt
|
|---|
| 5511 | 2.1 3H9R--WRM-16.result.pdbqt
|
|---|
| 5512 |
|
|---|
| 5513 | 0 H-bonds
|
|---|
| 5514 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 5515 |
|
|---|
| 5516 |
|
|---|
| 5517 |
|
|---|
| 5518 | 0 hydrogen bonds found
|
|---|
| 5519 |
|
|---|
| 5520 | > select :UNL
|
|---|
| 5521 |
|
|---|
| 5522 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 5523 |
|
|---|
| 5524 | > label sel text "Ligand "
|
|---|
| 5525 |
|
|---|
| 5526 | > label height 1
|
|---|
| 5527 |
|
|---|
| 5528 | > ~select
|
|---|
| 5529 |
|
|---|
| 5530 | Nothing selected
|
|---|
| 5531 |
|
|---|
| 5532 | > 2dlabels text "Binding Energy: -10.1 kcal/mol" color red size 18 xpos .03
|
|---|
| 5533 | > ypos .95
|
|---|
| 5534 |
|
|---|
| 5535 | > 2dlabels text "3H9R WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 5536 |
|
|---|
| 5537 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3H9R--
|
|---|
| 5538 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 5539 | > true
|
|---|
| 5540 |
|
|---|
| 5541 | > select :UNL
|
|---|
| 5542 |
|
|---|
| 5543 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 5544 |
|
|---|
| 5545 | > view sel
|
|---|
| 5546 |
|
|---|
| 5547 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3H9R--
|
|---|
| 5548 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 5549 | > true
|
|---|
| 5550 |
|
|---|
| 5551 | > close
|
|---|
| 5552 |
|
|---|
| 5553 | > wait 5
|
|---|
| 5554 |
|
|---|
| 5555 | > set bgColor white
|
|---|
| 5556 |
|
|---|
| 5557 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1A5E.pdbqt
|
|---|
| 5558 |
|
|---|
| 5559 | Chain information for 1A5E.pdbqt #1
|
|---|
| 5560 | ---
|
|---|
| 5561 | Chain | Description
|
|---|
| 5562 | A | No description available
|
|---|
| 5563 |
|
|---|
| 5564 | Opened 1A5E.pdbqt containing 1 structures (2306 atoms, 2328 bonds)
|
|---|
| 5565 |
|
|---|
| 5566 | > wait 5
|
|---|
| 5567 |
|
|---|
| 5568 | > hide surfaces
|
|---|
| 5569 |
|
|---|
| 5570 | > hide atoms
|
|---|
| 5571 |
|
|---|
| 5572 | > show cartoons
|
|---|
| 5573 |
|
|---|
| 5574 | > wait 5
|
|---|
| 5575 |
|
|---|
| 5576 | > addh
|
|---|
| 5577 |
|
|---|
| 5578 | Summary of feedback from adding hydrogens to 1A5E.pdbqt #1
|
|---|
| 5579 | ---
|
|---|
| 5580 | notes | No usable SEQRES records for 1A5E.pdbqt (#1) chain A; guessing termini
|
|---|
| 5581 | instead
|
|---|
| 5582 | Chain-initial residues that are actual N termini: /A MET 1
|
|---|
| 5583 | Chain-initial residues that are not actual N termini:
|
|---|
| 5584 | Chain-final residues that are actual C termini: /A ASP 156
|
|---|
| 5585 | Chain-final residues that are not actual C termini:
|
|---|
| 5586 | 64 hydrogen bonds
|
|---|
| 5587 | 0 hydrogens added
|
|---|
| 5588 |
|
|---|
| 5589 |
|
|---|
| 5590 | > wait 5
|
|---|
| 5591 |
|
|---|
| 5592 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1A5E--
|
|---|
| 5593 | > WRM-16.result.pdbqt
|
|---|
| 5594 |
|
|---|
| 5595 | Summary of feedback from opening
|
|---|
| 5596 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1A5E--WRM-16.result.pdbqt
|
|---|
| 5597 | ---
|
|---|
| 5598 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 5599 | REMARK VINA RESULT: -6.6 0.000 0.000
|
|---|
| 5600 |
|
|---|
| 5601 | Ignored bad PDB record found on line 3
|
|---|
| 5602 | REMARK 5 active torsions:
|
|---|
| 5603 |
|
|---|
| 5604 | Ignored bad PDB record found on line 4
|
|---|
| 5605 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 5606 |
|
|---|
| 5607 | Ignored bad PDB record found on line 5
|
|---|
| 5608 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 5609 |
|
|---|
| 5610 | Ignored bad PDB record found on line 6
|
|---|
| 5611 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 5612 |
|
|---|
| 5613 | 184 messages similar to the above omitted
|
|---|
| 5614 |
|
|---|
| 5615 | Opened 1A5E--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 5616 | bonds)
|
|---|
| 5617 |
|
|---|
| 5618 | > wait 5
|
|---|
| 5619 |
|
|---|
| 5620 | > close #2.2-9
|
|---|
| 5621 |
|
|---|
| 5622 | > wait 5
|
|---|
| 5623 |
|
|---|
| 5624 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 5625 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1A5E--
|
|---|
| 5626 | > WRM-16.contacts.txt
|
|---|
| 5627 |
|
|---|
| 5628 |
|
|---|
| 5629 | Allowed overlap: -0.4
|
|---|
| 5630 | H-bond overlap reduction: 0.4
|
|---|
| 5631 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 5632 | Detect intra-residue contacts: False
|
|---|
| 5633 | Detect intra-molecule contacts: True
|
|---|
| 5634 |
|
|---|
| 5635 | 45 contacts
|
|---|
| 5636 | atom1 atom2 overlap distance
|
|---|
| 5637 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A ARG 112 1HH1 0.185 2.695
|
|---|
| 5638 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 O 1A5E.pdbqt #1/A ARG 112 1HH1 0.171 1.889
|
|---|
| 5639 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1A5E.pdbqt #1/A GLY 111 HA3 0.148 2.732
|
|---|
| 5640 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A ARG 112 HD3 0.134 2.626
|
|---|
| 5641 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A LEU 117 2HD1 0.063 2.817
|
|---|
| 5642 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1A5E.pdbqt #1/A GLY 111 CA 0.033 3.547
|
|---|
| 5643 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A ARG 112 NH1 0.030 3.475
|
|---|
| 5644 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 CD2 -0.013 3.593
|
|---|
| 5645 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A LEU 117 CD1 -0.018 3.598
|
|---|
| 5646 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 HB3 -0.022 2.782
|
|---|
| 5647 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 CG -0.036 3.616
|
|---|
| 5648 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1A5E.pdbqt #1/A PRO 151 HD3 -0.038 2.918
|
|---|
| 5649 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 HB3 -0.064 2.824
|
|---|
| 5650 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 CH2 -0.074 3.384
|
|---|
| 5651 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 HB3 -0.085 2.845
|
|---|
| 5652 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 O 1A5E.pdbqt #1/A ARG 112 NH1 -0.090 2.775
|
|---|
| 5653 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 O 1A5E.pdbqt #1/A LEU 117 3HD1 -0.118 2.538
|
|---|
| 5654 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A ARG 87 NH2 -0.119 3.624
|
|---|
| 5655 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 HB3 -0.131 2.891
|
|---|
| 5656 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1A5E.pdbqt #1/A PRO 151 CD -0.159 3.739
|
|---|
| 5657 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 HB3 -0.161 2.771
|
|---|
| 5658 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 CB -0.174 3.634
|
|---|
| 5659 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 O 1A5E.pdbqt #1/A ASP 108 OD2 -0.193 3.133
|
|---|
| 5660 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A GLY 111 N -0.213 3.598
|
|---|
| 5661 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 CH2 -0.218 3.678
|
|---|
| 5662 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 CB -0.221 3.681
|
|---|
| 5663 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1A5E.pdbqt #1/A GLY 111 N -0.227 3.732
|
|---|
| 5664 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A ARG 112 CD -0.234 3.694
|
|---|
| 5665 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 CZ3 -0.255 3.565
|
|---|
| 5666 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 CD1 -0.273 3.853
|
|---|
| 5667 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 O 1A5E.pdbqt #1/A LEU 117 CD1 -0.275 3.395
|
|---|
| 5668 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 CE2 -0.277 3.857
|
|---|
| 5669 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 CZ3 -0.277 3.587
|
|---|
| 5670 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 CH2 -0.289 3.599
|
|---|
| 5671 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A ARG 112 HD3 -0.299 3.059
|
|---|
| 5672 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 HB3 -0.303 2.913
|
|---|
| 5673 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A GLY 111 C -0.323 3.783
|
|---|
| 5674 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A ARG 112 1HH1 -0.339 2.949
|
|---|
| 5675 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1A5E.pdbqt #1/A TRP 110 C -0.352 3.932
|
|---|
| 5676 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A ARG 112 HB2 -0.359 3.119
|
|---|
| 5677 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A ARG 46 NH2 -0.361 3.746
|
|---|
| 5678 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A ARG 87 2HH2 -0.361 3.241
|
|---|
| 5679 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 CD1 -0.370 3.830
|
|---|
| 5680 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A TRP 110 CB -0.386 3.846
|
|---|
| 5681 | 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 C 1A5E.pdbqt #1/A ARG 112 1HH1 -0.399 3.009
|
|---|
| 5682 |
|
|---|
| 5683 |
|
|---|
| 5684 |
|
|---|
| 5685 | 45 contacts
|
|---|
| 5686 |
|
|---|
| 5687 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 5688 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1A5E--
|
|---|
| 5689 | > WRM-16.hbonds.txt
|
|---|
| 5690 |
|
|---|
| 5691 |
|
|---|
| 5692 | Finding intermodel H-bonds
|
|---|
| 5693 | Finding intramodel H-bonds
|
|---|
| 5694 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 5695 | Models used:
|
|---|
| 5696 | 1 1A5E.pdbqt
|
|---|
| 5697 | 2.1 1A5E--WRM-16.result.pdbqt
|
|---|
| 5698 |
|
|---|
| 5699 | 1 H-bonds
|
|---|
| 5700 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 5701 | 1A5E.pdbqt #1/A ARG 112 NH1 1A5E--WRM-16.result.pdbqt #2.1/? UNL 1 O 1A5E.pdbqt #1/A ARG 112 1HH1 2.775 1.889
|
|---|
| 5702 |
|
|---|
| 5703 |
|
|---|
| 5704 |
|
|---|
| 5705 | 1 hydrogen bonds found
|
|---|
| 5706 |
|
|---|
| 5707 | > select :UNL
|
|---|
| 5708 |
|
|---|
| 5709 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 5710 |
|
|---|
| 5711 | > label sel text "Ligand "
|
|---|
| 5712 |
|
|---|
| 5713 | > label height 1
|
|---|
| 5714 |
|
|---|
| 5715 | > ~select
|
|---|
| 5716 |
|
|---|
| 5717 | Nothing selected
|
|---|
| 5718 |
|
|---|
| 5719 | > 2dlabels text "Binding Energy: -6.6 kcal/mol" color red size 18 xpos .03
|
|---|
| 5720 | > ypos .95
|
|---|
| 5721 |
|
|---|
| 5722 | > 2dlabels text "1A5E WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 5723 |
|
|---|
| 5724 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1A5E--
|
|---|
| 5725 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 5726 | > true
|
|---|
| 5727 |
|
|---|
| 5728 | > select :UNL
|
|---|
| 5729 |
|
|---|
| 5730 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 5731 |
|
|---|
| 5732 | > view sel
|
|---|
| 5733 |
|
|---|
| 5734 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1A5E--
|
|---|
| 5735 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 5736 | > true
|
|---|
| 5737 |
|
|---|
| 5738 | > close
|
|---|
| 5739 |
|
|---|
| 5740 | > wait 5
|
|---|
| 5741 |
|
|---|
| 5742 | > set bgColor white
|
|---|
| 5743 |
|
|---|
| 5744 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1ES7.pdbqt
|
|---|
| 5745 |
|
|---|
| 5746 | Chain information for 1ES7.pdbqt #1
|
|---|
| 5747 | ---
|
|---|
| 5748 | Chain | Description
|
|---|
| 5749 | A C | No description available
|
|---|
| 5750 | B | No description available
|
|---|
| 5751 | D | No description available
|
|---|
| 5752 |
|
|---|
| 5753 | Opened 1ES7.pdbqt containing 1 structures (5745 atoms, 5815 bonds)
|
|---|
| 5754 |
|
|---|
| 5755 | > wait 5
|
|---|
| 5756 |
|
|---|
| 5757 | > hide surfaces
|
|---|
| 5758 |
|
|---|
| 5759 | > hide atoms
|
|---|
| 5760 |
|
|---|
| 5761 | > show cartoons
|
|---|
| 5762 |
|
|---|
| 5763 | > wait 5
|
|---|
| 5764 |
|
|---|
| 5765 | > addh
|
|---|
| 5766 |
|
|---|
| 5767 | Summary of feedback from adding hydrogens to 1ES7.pdbqt #1
|
|---|
| 5768 | ---
|
|---|
| 5769 | notes | No usable SEQRES records for 1ES7.pdbqt (#1) chain A; guessing termini
|
|---|
| 5770 | instead
|
|---|
| 5771 | No usable SEQRES records for 1ES7.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 5772 | No usable SEQRES records for 1ES7.pdbqt (#1) chain C; guessing termini instead
|
|---|
| 5773 | No usable SEQRES records for 1ES7.pdbqt (#1) chain D; guessing termini instead
|
|---|
| 5774 | Chain-initial residues that are actual N termini: /A LYS 11, /B THR 232, /C
|
|---|
| 5775 | LYS 511, /D THR 732
|
|---|
| 5776 | Chain-initial residues that are not actual N termini: /B GLU 270, /D GLU 770
|
|---|
| 5777 | Chain-final residues that are actual C termini: /A ARG 114, /B PRO 317, /C ARG
|
|---|
| 5778 | 614, /D ILE 820
|
|---|
| 5779 | Chain-final residues that are not actual C termini: /B ASP 266, /D ASP 766
|
|---|
| 5780 | 270 hydrogen bonds
|
|---|
| 5781 | Adding 'H' to /B GLU 270
|
|---|
| 5782 | Adding 'H' to /D GLU 770
|
|---|
| 5783 | /B ASP 266 is not terminus, removing H atom from 'C'
|
|---|
| 5784 | /D ASP 766 is not terminus, removing H atom from 'C'
|
|---|
| 5785 | 28 hydrogens added
|
|---|
| 5786 |
|
|---|
| 5787 |
|
|---|
| 5788 | > wait 5
|
|---|
| 5789 |
|
|---|
| 5790 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1ES7--
|
|---|
| 5791 | > WRM-16.result.pdbqt
|
|---|
| 5792 |
|
|---|
| 5793 | Summary of feedback from opening
|
|---|
| 5794 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1ES7--WRM-16.result.pdbqt
|
|---|
| 5795 | ---
|
|---|
| 5796 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 5797 | REMARK VINA RESULT: -7.5 0.000 0.000
|
|---|
| 5798 |
|
|---|
| 5799 | Ignored bad PDB record found on line 3
|
|---|
| 5800 | REMARK 5 active torsions:
|
|---|
| 5801 |
|
|---|
| 5802 | Ignored bad PDB record found on line 4
|
|---|
| 5803 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 5804 |
|
|---|
| 5805 | Ignored bad PDB record found on line 5
|
|---|
| 5806 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 5807 |
|
|---|
| 5808 | Ignored bad PDB record found on line 6
|
|---|
| 5809 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 5810 |
|
|---|
| 5811 | 184 messages similar to the above omitted
|
|---|
| 5812 |
|
|---|
| 5813 | Opened 1ES7--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 5814 | bonds)
|
|---|
| 5815 |
|
|---|
| 5816 | > wait 5
|
|---|
| 5817 |
|
|---|
| 5818 | > close #2.2-9
|
|---|
| 5819 |
|
|---|
| 5820 | > wait 5
|
|---|
| 5821 |
|
|---|
| 5822 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 5823 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1ES7--
|
|---|
| 5824 | > WRM-16.contacts.txt
|
|---|
| 5825 |
|
|---|
| 5826 |
|
|---|
| 5827 | Allowed overlap: -0.4
|
|---|
| 5828 | H-bond overlap reduction: 0.4
|
|---|
| 5829 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 5830 | Detect intra-residue contacts: False
|
|---|
| 5831 | Detect intra-molecule contacts: True
|
|---|
| 5832 |
|
|---|
| 5833 | 46 contacts
|
|---|
| 5834 | atom1 atom2 overlap distance
|
|---|
| 5835 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/B ASP 246 HN 0.266 2.614
|
|---|
| 5836 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A ARG 16 HN 0.165 1.855
|
|---|
| 5837 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/B PRO 245 HB2 0.115 2.645
|
|---|
| 5838 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A HIS 54 ND1 0.101 3.404
|
|---|
| 5839 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A HIS 54 HD1 0.099 2.781
|
|---|
| 5840 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A CYS 111 HN 0.038 2.022
|
|---|
| 5841 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A ARG 16 HB2 -0.021 2.781
|
|---|
| 5842 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A HIS 54 HB2 -0.077 2.687
|
|---|
| 5843 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/B ASP 246 N -0.107 3.612
|
|---|
| 5844 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A ASN 56 1HD2 -0.114 2.134
|
|---|
| 5845 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/B PRO 245 CB -0.134 3.594
|
|---|
| 5846 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A CYS 111 HN -0.134 2.744
|
|---|
| 5847 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A ASN 56 1HD2 -0.156 2.766
|
|---|
| 5848 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A ARG 16 N -0.177 2.822
|
|---|
| 5849 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A ARG 16 HN -0.181 2.791
|
|---|
| 5850 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/B ASP 246 CB -0.198 3.658
|
|---|
| 5851 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A ARG 16 HN -0.206 2.966
|
|---|
| 5852 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A GLY 110 HA1 -0.216 2.636
|
|---|
| 5853 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/B ASP 247 OD1 -0.230 3.470
|
|---|
| 5854 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/B ASP 246 OD2 -0.233 3.473
|
|---|
| 5855 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A HIS 54 HB2 -0.234 2.994
|
|---|
| 5856 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A HIS 54 CB -0.239 3.699
|
|---|
| 5857 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/B ASP 246 HB2 -0.244 3.004
|
|---|
| 5858 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A HIS 54 HB2 -0.248 3.128
|
|---|
| 5859 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/B ASP 246 HB2 -0.253 3.013
|
|---|
| 5860 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A CYS 111 O -0.274 3.364
|
|---|
| 5861 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A GLY 110 CA -0.280 3.400
|
|---|
| 5862 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A CYS 111 O -0.305 3.205
|
|---|
| 5863 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A ARG 16 CB -0.311 3.771
|
|---|
| 5864 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/B ASP 247 OD1 -0.316 3.556
|
|---|
| 5865 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A LYS 15 CA -0.326 3.446
|
|---|
| 5866 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A ARG 16 O -0.327 3.567
|
|---|
| 5867 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A ASN 56 2HD2 -0.328 2.388
|
|---|
| 5868 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A LYS 15 HA -0.330 2.750
|
|---|
| 5869 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/B ASP 247 OD2 -0.331 3.571
|
|---|
| 5870 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A HIS 54 CB -0.338 3.648
|
|---|
| 5871 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A CYS 111 N -0.338 3.573
|
|---|
| 5872 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A CYS 111 N -0.339 3.024
|
|---|
| 5873 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A CYS 111 O -0.361 3.301
|
|---|
| 5874 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A ASN 56 ND2 -0.363 3.598
|
|---|
| 5875 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A ARG 16 N -0.363 3.748
|
|---|
| 5876 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A ASN 56 ND2 -0.369 3.014
|
|---|
| 5877 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/B ASP 247 CG -0.374 3.834
|
|---|
| 5878 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A HIS 54 HB2 -0.375 2.985
|
|---|
| 5879 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A ASN 56 ND2 -0.381 3.066
|
|---|
| 5880 | 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 C 1ES7.pdbqt #1/A CYS 111 HN -0.394 3.274
|
|---|
| 5881 |
|
|---|
| 5882 |
|
|---|
| 5883 |
|
|---|
| 5884 | 46 contacts
|
|---|
| 5885 |
|
|---|
| 5886 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 5887 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1ES7--
|
|---|
| 5888 | > WRM-16.hbonds.txt
|
|---|
| 5889 |
|
|---|
| 5890 |
|
|---|
| 5891 | Finding intermodel H-bonds
|
|---|
| 5892 | Finding intramodel H-bonds
|
|---|
| 5893 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 5894 | Models used:
|
|---|
| 5895 | 1 1ES7.pdbqt
|
|---|
| 5896 | 2.1 1ES7--WRM-16.result.pdbqt
|
|---|
| 5897 |
|
|---|
| 5898 | 4 H-bonds
|
|---|
| 5899 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 5900 | 1ES7.pdbqt #1/A ARG 16 N 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A ARG 16 HN 2.822 1.855
|
|---|
| 5901 | 1ES7.pdbqt #1/A ASN 56 ND2 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A ASN 56 1HD2 3.014 2.134
|
|---|
| 5902 | 1ES7.pdbqt #1/A ASN 56 ND2 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A ASN 56 2HD2 3.066 2.388
|
|---|
| 5903 | 1ES7.pdbqt #1/A CYS 111 N 1ES7--WRM-16.result.pdbqt #2.1/? UNL 1 O 1ES7.pdbqt #1/A CYS 111 HN 3.024 2.022
|
|---|
| 5904 |
|
|---|
| 5905 |
|
|---|
| 5906 |
|
|---|
| 5907 | 4 hydrogen bonds found
|
|---|
| 5908 |
|
|---|
| 5909 | > select :UNL
|
|---|
| 5910 |
|
|---|
| 5911 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 5912 |
|
|---|
| 5913 | > label sel text "Ligand "
|
|---|
| 5914 |
|
|---|
| 5915 | > label height 1
|
|---|
| 5916 |
|
|---|
| 5917 | > ~select
|
|---|
| 5918 |
|
|---|
| 5919 | Nothing selected
|
|---|
| 5920 |
|
|---|
| 5921 | > 2dlabels text "Binding Energy: -7.5 kcal/mol" color red size 18 xpos .03
|
|---|
| 5922 | > ypos .95
|
|---|
| 5923 |
|
|---|
| 5924 | > 2dlabels text "1ES7 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 5925 |
|
|---|
| 5926 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1ES7--
|
|---|
| 5927 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 5928 | > true
|
|---|
| 5929 |
|
|---|
| 5930 | > select :UNL
|
|---|
| 5931 |
|
|---|
| 5932 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 5933 |
|
|---|
| 5934 | > view sel
|
|---|
| 5935 |
|
|---|
| 5936 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1ES7--
|
|---|
| 5937 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 5938 | > true
|
|---|
| 5939 |
|
|---|
| 5940 | > close
|
|---|
| 5941 |
|
|---|
| 5942 | > wait 5
|
|---|
| 5943 |
|
|---|
| 5944 | > set bgColor white
|
|---|
| 5945 |
|
|---|
| 5946 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/3TGX.pdbqt
|
|---|
| 5947 |
|
|---|
| 5948 | Chain information for 3TGX.pdbqt #1
|
|---|
| 5949 | ---
|
|---|
| 5950 | Chain | Description
|
|---|
| 5951 | A M O | No description available
|
|---|
| 5952 | B | No description available
|
|---|
| 5953 | C G I K | No description available
|
|---|
| 5954 | D | No description available
|
|---|
| 5955 | E | No description available
|
|---|
| 5956 | F | No description available
|
|---|
| 5957 | H | No description available
|
|---|
| 5958 | J | No description available
|
|---|
| 5959 | L | No description available
|
|---|
| 5960 | N | No description available
|
|---|
| 5961 | P | No description available
|
|---|
| 5962 |
|
|---|
| 5963 | Opened 3TGX.pdbqt containing 1 structures (41174 atoms, 41719 bonds)
|
|---|
| 5964 |
|
|---|
| 5965 | > wait 5
|
|---|
| 5966 |
|
|---|
| 5967 | > hide surfaces
|
|---|
| 5968 |
|
|---|
| 5969 | > hide atoms
|
|---|
| 5970 |
|
|---|
| 5971 | > show cartoons
|
|---|
| 5972 |
|
|---|
| 5973 | > wait 5
|
|---|
| 5974 |
|
|---|
| 5975 | > addh
|
|---|
| 5976 |
|
|---|
| 5977 | Summary of feedback from adding hydrogens to 3TGX.pdbqt #1
|
|---|
| 5978 | ---
|
|---|
| 5979 | warning | Not adding hydrogens to /J ARG 126 CB because it is missing heavy-
|
|---|
| 5980 | atom bond partners
|
|---|
| 5981 | notes | No usable SEQRES records for 3TGX.pdbqt (#1) chain A; guessing termini
|
|---|
| 5982 | instead
|
|---|
| 5983 | No usable SEQRES records for 3TGX.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 5984 | No usable SEQRES records for 3TGX.pdbqt (#1) chain C; guessing termini instead
|
|---|
| 5985 | No usable SEQRES records for 3TGX.pdbqt (#1) chain D; guessing termini instead
|
|---|
| 5986 | No usable SEQRES records for 3TGX.pdbqt (#1) chain E; guessing termini instead
|
|---|
| 5987 | 11 messages similar to the above omitted
|
|---|
| 5988 | Chain-initial residues that are actual N termini: /A CYS 1, /B GLY 2, /C CYS
|
|---|
| 5989 | 1, /D GLY 2, /E CYS 1, /F GLY 2, /G CYS 1, /H ASP 4, /I CYS 1, /J GLY 2, /K
|
|---|
| 5990 | CYS 1, /L ASP 4, /M CYS 1, /N ASP 4, /O CYS 1, /P ASP 4
|
|---|
| 5991 | Chain-initial residues that are not actual N termini: /B HIS 89, /D LEU 91, /F
|
|---|
| 5992 | THR 92, /H GLN 87, /J LEU 91, /L LEU 91, /N THR 92, /P THR 92
|
|---|
| 5993 | Chain-final residues that are actual C termini: /A SER 208, /B LEU 123, /C GLU
|
|---|
| 5994 | 209, /D LEU 123, /E GLN 207, /F LEU 123, /G GLU 209, /H LEU 123, /I GLU 209,
|
|---|
| 5995 | /J ARG 126, /K GLU 209, /L HIS 122, /M SER 208, /N HIS 120, /O SER 208, /P LEU
|
|---|
| 5996 | 123
|
|---|
| 5997 | Chain-final residues that are not actual C termini: /B THR 81, /D ARG 85, /F
|
|---|
| 5998 | ASN 82, /H ASN 82, /J THR 81, /L THR 81, /N THR 81, /P THR 81
|
|---|
| 5999 | 1792 hydrogen bonds
|
|---|
| 6000 | Adding 'H' to /B HIS 89
|
|---|
| 6001 | Adding 'H' to /D LEU 91
|
|---|
| 6002 | Adding 'H' to /F THR 92
|
|---|
| 6003 | Adding 'H' to /H GLN 87
|
|---|
| 6004 | Adding 'H' to /J LEU 91
|
|---|
| 6005 | 3 messages similar to the above omitted
|
|---|
| 6006 | /B THR 81 is not terminus, removing H atom from 'C'
|
|---|
| 6007 | /D ARG 85 is not terminus, removing H atom from 'C'
|
|---|
| 6008 | /F ASN 82 is not terminus, removing H atom from 'C'
|
|---|
| 6009 | /H ASN 82 is not terminus, removing H atom from 'C'
|
|---|
| 6010 | /J THR 81 is not terminus, removing H atom from 'C'
|
|---|
| 6011 | 3 messages similar to the above omitted
|
|---|
| 6012 | 80 hydrogens added
|
|---|
| 6013 |
|
|---|
| 6014 |
|
|---|
| 6015 | > wait 5
|
|---|
| 6016 |
|
|---|
| 6017 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/3TGX--
|
|---|
| 6018 | > WRM-16.result.pdbqt
|
|---|
| 6019 |
|
|---|
| 6020 | Summary of feedback from opening
|
|---|
| 6021 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/3TGX--WRM-16.result.pdbqt
|
|---|
| 6022 | ---
|
|---|
| 6023 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 6024 | REMARK VINA RESULT: -8.5 0.000 0.000
|
|---|
| 6025 |
|
|---|
| 6026 | Ignored bad PDB record found on line 3
|
|---|
| 6027 | REMARK 5 active torsions:
|
|---|
| 6028 |
|
|---|
| 6029 | Ignored bad PDB record found on line 4
|
|---|
| 6030 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 6031 |
|
|---|
| 6032 | Ignored bad PDB record found on line 5
|
|---|
| 6033 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 6034 |
|
|---|
| 6035 | Ignored bad PDB record found on line 6
|
|---|
| 6036 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 6037 |
|
|---|
| 6038 | 184 messages similar to the above omitted
|
|---|
| 6039 |
|
|---|
| 6040 | Opened 3TGX--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 6041 | bonds)
|
|---|
| 6042 |
|
|---|
| 6043 | > wait 5
|
|---|
| 6044 |
|
|---|
| 6045 | > close #2.2-9
|
|---|
| 6046 |
|
|---|
| 6047 | > wait 5
|
|---|
| 6048 |
|
|---|
| 6049 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 6050 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3TGX--
|
|---|
| 6051 | > WRM-16.contacts.txt
|
|---|
| 6052 |
|
|---|
| 6053 |
|
|---|
| 6054 | Allowed overlap: -0.4
|
|---|
| 6055 | H-bond overlap reduction: 0.4
|
|---|
| 6056 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 6057 | Detect intra-residue contacts: False
|
|---|
| 6058 | Detect intra-molecule contacts: True
|
|---|
| 6059 |
|
|---|
| 6060 | 84 contacts
|
|---|
| 6061 | atom1 atom2 overlap distance
|
|---|
| 6062 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/A ASN 22 1HD2 0.702 2.058
|
|---|
| 6063 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M ASN 22 2HD2 0.553 2.327
|
|---|
| 6064 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3TGX.pdbqt #1/F ARG 65 HB2 0.512 2.368
|
|---|
| 6065 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/A ASN 22 ND2 0.484 2.901
|
|---|
| 6066 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/A ASP 81 OD1 0.349 3.011
|
|---|
| 6067 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M TYR 86 HH 0.297 2.463
|
|---|
| 6068 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/E ALA 127 HB1 0.227 2.533
|
|---|
| 6069 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 1HE2 0.207 2.403
|
|---|
| 6070 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 HG1 0.181 2.579
|
|---|
| 6071 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 CB 0.180 3.400
|
|---|
| 6072 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M TYR 86 OH 0.166 3.094
|
|---|
| 6073 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M ASN 22 ND2 0.163 3.342
|
|---|
| 6074 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ASN 62 CB 0.149 3.431
|
|---|
| 6075 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M TRP 21 CD1 0.133 3.447
|
|---|
| 6076 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3TGX.pdbqt #1/F ARG 65 NE 0.132 3.373
|
|---|
| 6077 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ASN 62 HB1 0.131 2.749
|
|---|
| 6078 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M TRP 21 HD1 0.115 2.765
|
|---|
| 6079 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3TGX.pdbqt #1/F ARG 65 CB 0.110 3.470
|
|---|
| 6080 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 HB2 0.094 2.786
|
|---|
| 6081 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3TGX.pdbqt #1/F ILE 66 CG1 0.089 3.491
|
|---|
| 6082 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/A GLN 82 HN 0.077 2.683
|
|---|
| 6083 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/E ALA 127 CB 0.016 3.444
|
|---|
| 6084 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M TRP 21 NE1 0.005 3.500
|
|---|
| 6085 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3TGX.pdbqt #1/F ILE 66 2HG1 0.001 2.879
|
|---|
| 6086 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ASN 62 2HD2 -0.001 2.611
|
|---|
| 6087 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3TGX.pdbqt #1/E ALA 127 CB -0.006 3.586
|
|---|
| 6088 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/A ASP 81 OD1 -0.008 3.248
|
|---|
| 6089 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3TGX.pdbqt #1/F ILE 66 1HG1 -0.043 2.923
|
|---|
| 6090 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/A GLN 82 HN -0.056 2.816
|
|---|
| 6091 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M TRP 21 HE1 -0.056 2.936
|
|---|
| 6092 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M ASN 22 ND2 -0.057 3.292
|
|---|
| 6093 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 O 3TGX.pdbqt #1/M GLN 82 1HE2 -0.067 2.127
|
|---|
| 6094 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 CG -0.098 3.678
|
|---|
| 6095 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 NE2 -0.104 3.339
|
|---|
| 6096 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ASN 62 ND2 -0.107 3.612
|
|---|
| 6097 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ARG 65 HD2 -0.112 2.872
|
|---|
| 6098 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ASN 62 HB1 -0.119 2.879
|
|---|
| 6099 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 HB1 -0.134 3.014
|
|---|
| 6100 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3TGX.pdbqt #1/E ALA 127 HB1 -0.143 3.023
|
|---|
| 6101 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ASN 62 2HD2 -0.158 2.768
|
|---|
| 6102 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M HIS 24 CG -0.159 3.619
|
|---|
| 6103 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 HG1 -0.159 3.039
|
|---|
| 6104 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 O 3TGX.pdbqt #1/F ASN 62 HB2 -0.163 2.623
|
|---|
| 6105 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/A ASN 22 1HD2 -0.178 2.938
|
|---|
| 6106 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/A ASN 22 ND2 -0.185 3.690
|
|---|
| 6107 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 CG -0.188 3.648
|
|---|
| 6108 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/A GLN 82 N -0.192 3.577
|
|---|
| 6109 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 HB2 -0.208 2.818
|
|---|
| 6110 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ASN 62 2HD2 -0.228 3.108
|
|---|
| 6111 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ASN 62 HB2 -0.235 3.115
|
|---|
| 6112 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ASN 62 2HD2 -0.240 3.000
|
|---|
| 6113 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M HIS 24 CE1 -0.248 3.708
|
|---|
| 6114 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M TYR 86 HH -0.249 3.009
|
|---|
| 6115 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ASN 62 CG -0.260 3.840
|
|---|
| 6116 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ASN 62 CB -0.262 3.842
|
|---|
| 6117 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3TGX.pdbqt #1/F ARG 65 CD -0.265 3.845
|
|---|
| 6118 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3TGX.pdbqt #1/F ARG 65 CZ -0.271 3.851
|
|---|
| 6119 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3TGX.pdbqt #1/F ILE 66 N -0.274 3.779
|
|---|
| 6120 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 HB1 -0.281 3.161
|
|---|
| 6121 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3TGX.pdbqt #1/F ARG 65 HE -0.296 3.176
|
|---|
| 6122 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ASN 62 HB2 -0.296 3.176
|
|---|
| 6123 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ASN 62 ND2 -0.298 3.533
|
|---|
| 6124 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 O 3TGX.pdbqt #1/A ASP 81 OD1 -0.308 3.248
|
|---|
| 6125 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3TGX.pdbqt #1/E ALA 127 HB2 -0.313 3.193
|
|---|
| 6126 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 HB2 -0.319 2.929
|
|---|
| 6127 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M TYR 86 OH -0.336 3.596
|
|---|
| 6128 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ARG 65 CD -0.339 3.799
|
|---|
| 6129 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 HB2 -0.343 2.953
|
|---|
| 6130 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ARG 65 CB -0.346 3.806
|
|---|
| 6131 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 HG1 -0.347 3.107
|
|---|
| 6132 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M HIS 24 CD2 -0.354 3.814
|
|---|
| 6133 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 O 3TGX.pdbqt #1/M GLN 82 HB2 -0.356 2.816
|
|---|
| 6134 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ARG 65 HB2 -0.357 3.117
|
|---|
| 6135 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/A ASN 22 ND2 -0.361 3.746
|
|---|
| 6136 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ASN 62 2HD2 -0.361 3.121
|
|---|
| 6137 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 O 3TGX.pdbqt #1/M GLN 82 CG -0.362 3.522
|
|---|
| 6138 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/F ASN 62 ND2 -0.368 3.603
|
|---|
| 6139 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/A ASN 22 1HD2 -0.370 3.250
|
|---|
| 6140 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 CB -0.370 3.680
|
|---|
| 6141 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M GLN 82 1HE2 -0.388 3.268
|
|---|
| 6142 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M HIS 24 NE2 -0.389 3.774
|
|---|
| 6143 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/A GLN 82 HB2 -0.390 3.150
|
|---|
| 6144 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 C 3TGX.pdbqt #1/M HIS 24 ND1 -0.394 3.779
|
|---|
| 6145 | 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 O 3TGX.pdbqt #1/A ASN 22 ND2 -0.395 3.080
|
|---|
| 6146 |
|
|---|
| 6147 |
|
|---|
| 6148 |
|
|---|
| 6149 | 84 contacts
|
|---|
| 6150 |
|
|---|
| 6151 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 6152 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3TGX--
|
|---|
| 6153 | > WRM-16.hbonds.txt
|
|---|
| 6154 |
|
|---|
| 6155 |
|
|---|
| 6156 | Finding intermodel H-bonds
|
|---|
| 6157 | Finding intramodel H-bonds
|
|---|
| 6158 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 6159 | Models used:
|
|---|
| 6160 | 1 3TGX.pdbqt
|
|---|
| 6161 | 2.1 3TGX--WRM-16.result.pdbqt
|
|---|
| 6162 |
|
|---|
| 6163 | 1 H-bonds
|
|---|
| 6164 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 6165 | 3TGX.pdbqt #1/M GLN 82 NE2 3TGX--WRM-16.result.pdbqt #2.1/? UNL 1 O 3TGX.pdbqt #1/M GLN 82 1HE2 3.121 2.127
|
|---|
| 6166 |
|
|---|
| 6167 |
|
|---|
| 6168 |
|
|---|
| 6169 | 1 hydrogen bonds found
|
|---|
| 6170 |
|
|---|
| 6171 | > select :UNL
|
|---|
| 6172 |
|
|---|
| 6173 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 6174 |
|
|---|
| 6175 | > label sel text "Ligand "
|
|---|
| 6176 |
|
|---|
| 6177 | > label height 1
|
|---|
| 6178 |
|
|---|
| 6179 | > ~select
|
|---|
| 6180 |
|
|---|
| 6181 | Nothing selected
|
|---|
| 6182 |
|
|---|
| 6183 | > 2dlabels text "Binding Energy: -8.5 kcal/mol" color red size 18 xpos .03
|
|---|
| 6184 | > ypos .95
|
|---|
| 6185 |
|
|---|
| 6186 | > 2dlabels text "3TGX WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 6187 |
|
|---|
| 6188 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3TGX--
|
|---|
| 6189 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 6190 | > true
|
|---|
| 6191 |
|
|---|
| 6192 | > select :UNL
|
|---|
| 6193 |
|
|---|
| 6194 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 6195 |
|
|---|
| 6196 | > view sel
|
|---|
| 6197 |
|
|---|
| 6198 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3TGX--
|
|---|
| 6199 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 6200 | > true
|
|---|
| 6201 |
|
|---|
| 6202 | > close
|
|---|
| 6203 |
|
|---|
| 6204 | > wait 5
|
|---|
| 6205 |
|
|---|
| 6206 | > set bgColor white
|
|---|
| 6207 |
|
|---|
| 6208 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/4JUP.pdbqt
|
|---|
| 6209 |
|
|---|
| 6210 | Chain information for 4JUP.pdbqt #1
|
|---|
| 6211 | ---
|
|---|
| 6212 | Chain | Description
|
|---|
| 6213 | A B | No description available
|
|---|
| 6214 |
|
|---|
| 6215 | Opened 4JUP.pdbqt containing 1 structures (2664 atoms, 2690 bonds)
|
|---|
| 6216 |
|
|---|
| 6217 | > wait 5
|
|---|
| 6218 |
|
|---|
| 6219 | > hide surfaces
|
|---|
| 6220 |
|
|---|
| 6221 | > hide atoms
|
|---|
| 6222 |
|
|---|
| 6223 | > show cartoons
|
|---|
| 6224 |
|
|---|
| 6225 | > wait 5
|
|---|
| 6226 |
|
|---|
| 6227 | > addh
|
|---|
| 6228 |
|
|---|
| 6229 | Summary of feedback from adding hydrogens to 4JUP.pdbqt #1
|
|---|
| 6230 | ---
|
|---|
| 6231 | notes | No usable SEQRES records for 4JUP.pdbqt (#1) chain A; guessing termini
|
|---|
| 6232 | instead
|
|---|
| 6233 | No usable SEQRES records for 4JUP.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 6234 | Chain-initial residues that are actual N termini: /A LEU 22, /B LEU 22
|
|---|
| 6235 | Chain-initial residues that are not actual N termini: /A ASN 71, /B ASN 71
|
|---|
| 6236 | Chain-final residues that are actual C termini: /A GLY 108, /B GLY 108
|
|---|
| 6237 | Chain-final residues that are not actual C termini: /A ALA 63, /B ALA 63
|
|---|
| 6238 | 116 hydrogen bonds
|
|---|
| 6239 | Adding 'H' to /A ASN 71
|
|---|
| 6240 | Adding 'H' to /B ASN 71
|
|---|
| 6241 | /A ALA 63 is not terminus, removing H atom from 'C'
|
|---|
| 6242 | /B ALA 63 is not terminus, removing H atom from 'C'
|
|---|
| 6243 | -2 hydrogens added
|
|---|
| 6244 |
|
|---|
| 6245 |
|
|---|
| 6246 | > wait 5
|
|---|
| 6247 |
|
|---|
| 6248 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/4JUP--
|
|---|
| 6249 | > WRM-16.result.pdbqt
|
|---|
| 6250 |
|
|---|
| 6251 | Summary of feedback from opening
|
|---|
| 6252 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/4JUP--WRM-16.result.pdbqt
|
|---|
| 6253 | ---
|
|---|
| 6254 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 6255 | REMARK VINA RESULT: -7.9 0.000 0.000
|
|---|
| 6256 |
|
|---|
| 6257 | Ignored bad PDB record found on line 3
|
|---|
| 6258 | REMARK 5 active torsions:
|
|---|
| 6259 |
|
|---|
| 6260 | Ignored bad PDB record found on line 4
|
|---|
| 6261 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 6262 |
|
|---|
| 6263 | Ignored bad PDB record found on line 5
|
|---|
| 6264 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 6265 |
|
|---|
| 6266 | Ignored bad PDB record found on line 6
|
|---|
| 6267 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 6268 |
|
|---|
| 6269 | 184 messages similar to the above omitted
|
|---|
| 6270 |
|
|---|
| 6271 | Opened 4JUP--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 6272 | bonds)
|
|---|
| 6273 |
|
|---|
| 6274 | > wait 5
|
|---|
| 6275 |
|
|---|
| 6276 | > close #2.2-9
|
|---|
| 6277 |
|
|---|
| 6278 | > wait 5
|
|---|
| 6279 |
|
|---|
| 6280 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 6281 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/4JUP--
|
|---|
| 6282 | > WRM-16.contacts.txt
|
|---|
| 6283 |
|
|---|
| 6284 |
|
|---|
| 6285 | Allowed overlap: -0.4
|
|---|
| 6286 | H-bond overlap reduction: 0.4
|
|---|
| 6287 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 6288 | Detect intra-residue contacts: False
|
|---|
| 6289 | Detect intra-molecule contacts: True
|
|---|
| 6290 |
|
|---|
| 6291 | 77 contacts
|
|---|
| 6292 | atom1 atom2 overlap distance
|
|---|
| 6293 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 O 4JUP.pdbqt #1/B ASN 71 HA 0.493 1.967
|
|---|
| 6294 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B HIS 31 HA 0.445 2.315
|
|---|
| 6295 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B ARG 35 HB1 0.307 2.573
|
|---|
| 6296 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B SER 34 HG 0.303 2.457
|
|---|
| 6297 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B HIS 31 O 0.286 3.074
|
|---|
| 6298 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ASP 78 HB1 0.217 2.663
|
|---|
| 6299 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B ARG 35 HD2 0.197 2.683
|
|---|
| 6300 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 O 4JUP.pdbqt #1/B ASN 71 CA 0.183 2.977
|
|---|
| 6301 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B ARG 30 HG2 0.161 2.599
|
|---|
| 6302 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 O 4JUP.pdbqt #1/B HIS 31 CE1 0.142 3.018
|
|---|
| 6303 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B SER 34 HG 0.130 2.630
|
|---|
| 6304 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ARG 75 2HH2 0.110 2.770
|
|---|
| 6305 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B ARG 35 CB 0.083 3.497
|
|---|
| 6306 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ILE 79 HA 0.074 2.686
|
|---|
| 6307 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B HIS 31 CA 0.055 3.405
|
|---|
| 6308 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B ARG 30 CG 0.047 3.413
|
|---|
| 6309 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 O 4JUP.pdbqt #1/A ARG 75 2HH2 0.027 1.993
|
|---|
| 6310 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A THR 82 HG1 -0.010 2.770
|
|---|
| 6311 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ASP 78 HB1 -0.017 2.777
|
|---|
| 6312 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B SER 34 HG -0.018 2.778
|
|---|
| 6313 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ARG 75 2HH1 -0.024 2.634
|
|---|
| 6314 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ARG 75 NH2 -0.029 3.534
|
|---|
| 6315 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ASP 78 CB -0.049 3.629
|
|---|
| 6316 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B SER 34 OG -0.079 3.339
|
|---|
| 6317 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A THR 82 HG1 -0.087 2.697
|
|---|
| 6318 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 4JUP.pdbqt #1/A THR 82 HG1 -0.105 2.985
|
|---|
| 6319 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B ARG 35 CD -0.111 3.691
|
|---|
| 6320 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B ASN 71 HA -0.119 2.999
|
|---|
| 6321 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ASP 78 OD2 -0.153 3.243
|
|---|
| 6322 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 O 4JUP.pdbqt #1/A ARG 75 NH2 -0.159 2.804
|
|---|
| 6323 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ASP 78 OD2 -0.165 3.255
|
|---|
| 6324 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 4JUP.pdbqt #1/A THR 82 1HG2 -0.181 3.061
|
|---|
| 6325 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A THR 82 OG1 -0.189 3.449
|
|---|
| 6326 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B HIS 31 HA -0.191 2.951
|
|---|
| 6327 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B HIS 31 CE1 -0.199 3.779
|
|---|
| 6328 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ARG 30 HD2 -0.203 2.963
|
|---|
| 6329 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ARG 30 CD -0.205 3.665
|
|---|
| 6330 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ILE 79 1HG1 -0.205 2.965
|
|---|
| 6331 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ARG 75 2HH2 -0.206 2.816
|
|---|
| 6332 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ARG 75 NH1 -0.210 3.445
|
|---|
| 6333 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B ARG 30 HG2 -0.213 2.973
|
|---|
| 6334 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ASN 71 2HD2 -0.213 3.093
|
|---|
| 6335 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ILE 79 CA -0.215 3.675
|
|---|
| 6336 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B SER 34 HB1 -0.220 3.100
|
|---|
| 6337 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 4JUP.pdbqt #1/A ILE 79 CG1 -0.228 3.808
|
|---|
| 6338 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B SER 34 OG -0.243 3.503
|
|---|
| 6339 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ASP 78 CG -0.244 3.824
|
|---|
| 6340 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ARG 75 2HH1 -0.246 2.856
|
|---|
| 6341 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 4JUP.pdbqt #1/A ILE 79 1HG1 -0.248 3.128
|
|---|
| 6342 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ASP 78 OD2 -0.258 3.498
|
|---|
| 6343 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B ASN 71 OD1 -0.262 3.622
|
|---|
| 6344 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B SER 34 CB -0.272 3.732
|
|---|
| 6345 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 O 4JUP.pdbqt #1/B ASN 71 HB2 -0.297 2.717
|
|---|
| 6346 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 O 4JUP.pdbqt #1/B ASN 71 CB -0.302 3.422
|
|---|
| 6347 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 O 4JUP.pdbqt #1/B HIS 31 ND1 -0.304 2.989
|
|---|
| 6348 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ASN 71 ND2 -0.305 3.810
|
|---|
| 6349 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B HIS 31 C -0.306 3.886
|
|---|
| 6350 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 O 4JUP.pdbqt #1/B ASN 71 CG -0.306 3.426
|
|---|
| 6351 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ASP 78 CB -0.308 3.768
|
|---|
| 6352 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B ARG 30 C -0.314 3.774
|
|---|
| 6353 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B SER 34 OG -0.315 3.575
|
|---|
| 6354 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B ARG 30 CG -0.316 3.776
|
|---|
| 6355 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ASP 78 C -0.326 3.786
|
|---|
| 6356 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B SER 34 HG -0.329 3.089
|
|---|
| 6357 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B HIS 31 ND1 -0.343 3.848
|
|---|
| 6358 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ASP 78 OD1 -0.346 3.706
|
|---|
| 6359 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B ARG 30 HG1 -0.355 3.115
|
|---|
| 6360 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ARG 75 NH2 -0.360 3.595
|
|---|
| 6361 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B ARG 35 CA -0.362 3.942
|
|---|
| 6362 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ASP 78 CG -0.365 3.675
|
|---|
| 6363 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B SER 34 HB1 -0.370 3.130
|
|---|
| 6364 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B ASN 71 HA -0.375 2.985
|
|---|
| 6365 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 O 4JUP.pdbqt #1/A ARG 75 CZ -0.378 3.498
|
|---|
| 6366 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ARG 30 NH1 -0.384 3.769
|
|---|
| 6367 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ASP 78 C -0.385 3.845
|
|---|
| 6368 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/B SER 34 CB -0.388 3.698
|
|---|
| 6369 | 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 C 4JUP.pdbqt #1/A ARG 75 2HH1 -0.396 3.276
|
|---|
| 6370 |
|
|---|
| 6371 |
|
|---|
| 6372 |
|
|---|
| 6373 | 77 contacts
|
|---|
| 6374 |
|
|---|
| 6375 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 6376 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/4JUP--
|
|---|
| 6377 | > WRM-16.hbonds.txt
|
|---|
| 6378 |
|
|---|
| 6379 |
|
|---|
| 6380 | Finding intermodel H-bonds
|
|---|
| 6381 | Finding intramodel H-bonds
|
|---|
| 6382 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 6383 | Models used:
|
|---|
| 6384 | 1 4JUP.pdbqt
|
|---|
| 6385 | 2.1 4JUP--WRM-16.result.pdbqt
|
|---|
| 6386 |
|
|---|
| 6387 | 1 H-bonds
|
|---|
| 6388 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 6389 | 4JUP.pdbqt #1/A ARG 75 NH2 4JUP--WRM-16.result.pdbqt #2.1/? UNL 1 O 4JUP.pdbqt #1/A ARG 75 2HH2 2.804 1.993
|
|---|
| 6390 |
|
|---|
| 6391 |
|
|---|
| 6392 |
|
|---|
| 6393 | 1 hydrogen bonds found
|
|---|
| 6394 |
|
|---|
| 6395 | > select :UNL
|
|---|
| 6396 |
|
|---|
| 6397 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 6398 |
|
|---|
| 6399 | > label sel text "Ligand "
|
|---|
| 6400 |
|
|---|
| 6401 | > label height 1
|
|---|
| 6402 |
|
|---|
| 6403 | > ~select
|
|---|
| 6404 |
|
|---|
| 6405 | Nothing selected
|
|---|
| 6406 |
|
|---|
| 6407 | > 2dlabels text "Binding Energy: -7.9 kcal/mol" color red size 18 xpos .03
|
|---|
| 6408 | > ypos .95
|
|---|
| 6409 |
|
|---|
| 6410 | > 2dlabels text "4JUP WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 6411 |
|
|---|
| 6412 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/4JUP--
|
|---|
| 6413 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 6414 | > true
|
|---|
| 6415 |
|
|---|
| 6416 | > select :UNL
|
|---|
| 6417 |
|
|---|
| 6418 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 6419 |
|
|---|
| 6420 | > view sel
|
|---|
| 6421 |
|
|---|
| 6422 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/4JUP--
|
|---|
| 6423 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 6424 | > true
|
|---|
| 6425 |
|
|---|
| 6426 | > close
|
|---|
| 6427 |
|
|---|
| 6428 | > wait 5
|
|---|
| 6429 |
|
|---|
| 6430 | > set bgColor white
|
|---|
| 6431 |
|
|---|
| 6432 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1FLI.pdbqt
|
|---|
| 6433 |
|
|---|
| 6434 | Chain information for 1FLI.pdbqt #1
|
|---|
| 6435 | ---
|
|---|
| 6436 | Chain | Description
|
|---|
| 6437 | A | No description available
|
|---|
| 6438 |
|
|---|
| 6439 | Opened 1FLI.pdbqt containing 1 structures (1589 atoms, 1612 bonds)
|
|---|
| 6440 |
|
|---|
| 6441 | > wait 5
|
|---|
| 6442 |
|
|---|
| 6443 | > hide surfaces
|
|---|
| 6444 |
|
|---|
| 6445 | > hide atoms
|
|---|
| 6446 |
|
|---|
| 6447 | > show cartoons
|
|---|
| 6448 |
|
|---|
| 6449 | > wait 5
|
|---|
| 6450 |
|
|---|
| 6451 | > addh
|
|---|
| 6452 |
|
|---|
| 6453 | Summary of feedback from adding hydrogens to 1FLI.pdbqt #1
|
|---|
| 6454 | ---
|
|---|
| 6455 | notes | No usable SEQRES records for 1FLI.pdbqt (#1) chain A; guessing termini
|
|---|
| 6456 | instead
|
|---|
| 6457 | Chain-initial residues that are actual N termini: /A PRO 276
|
|---|
| 6458 | Chain-initial residues that are not actual N termini:
|
|---|
| 6459 | Chain-final residues that are actual C termini: /A PRO 373
|
|---|
| 6460 | Chain-final residues that are not actual C termini:
|
|---|
| 6461 | 38 hydrogen bonds
|
|---|
| 6462 | 1 hydrogens added
|
|---|
| 6463 |
|
|---|
| 6464 |
|
|---|
| 6465 | > wait 5
|
|---|
| 6466 |
|
|---|
| 6467 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1FLI--
|
|---|
| 6468 | > WRM-16.result.pdbqt
|
|---|
| 6469 |
|
|---|
| 6470 | Summary of feedback from opening
|
|---|
| 6471 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1FLI--WRM-16.result.pdbqt
|
|---|
| 6472 | ---
|
|---|
| 6473 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 6474 | REMARK VINA RESULT: -7.4 0.000 0.000
|
|---|
| 6475 |
|
|---|
| 6476 | Ignored bad PDB record found on line 3
|
|---|
| 6477 | REMARK 5 active torsions:
|
|---|
| 6478 |
|
|---|
| 6479 | Ignored bad PDB record found on line 4
|
|---|
| 6480 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 6481 |
|
|---|
| 6482 | Ignored bad PDB record found on line 5
|
|---|
| 6483 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 6484 |
|
|---|
| 6485 | Ignored bad PDB record found on line 6
|
|---|
| 6486 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 6487 |
|
|---|
| 6488 | 184 messages similar to the above omitted
|
|---|
| 6489 |
|
|---|
| 6490 | Opened 1FLI--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 6491 | bonds)
|
|---|
| 6492 |
|
|---|
| 6493 | > wait 5
|
|---|
| 6494 |
|
|---|
| 6495 | > close #2.2-9
|
|---|
| 6496 |
|
|---|
| 6497 | > wait 5
|
|---|
| 6498 |
|
|---|
| 6499 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 6500 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1FLI--
|
|---|
| 6501 | > WRM-16.contacts.txt
|
|---|
| 6502 |
|
|---|
| 6503 |
|
|---|
| 6504 | Allowed overlap: -0.4
|
|---|
| 6505 | H-bond overlap reduction: 0.4
|
|---|
| 6506 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 6507 | Detect intra-residue contacts: False
|
|---|
| 6508 | Detect intra-molecule contacts: True
|
|---|
| 6509 |
|
|---|
| 6510 | 45 contacts
|
|---|
| 6511 | atom1 atom2 overlap distance
|
|---|
| 6512 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A PHE 309 HE1 0.444 2.316
|
|---|
| 6513 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 369 1HD2 0.247 2.513
|
|---|
| 6514 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 369 1HD2 0.080 2.680
|
|---|
| 6515 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A PHE 309 CE1 0.065 3.395
|
|---|
| 6516 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 288 HB3 0.055 2.555
|
|---|
| 6517 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A TRP 302 CZ3 0.017 3.563
|
|---|
| 6518 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 288 HB3 0.004 2.606
|
|---|
| 6519 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A PRO 371 HA -0.026 2.786
|
|---|
| 6520 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1FLI.pdbqt #1/A TRP 302 CD1 -0.029 3.609
|
|---|
| 6521 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A TRP 302 HZ3 -0.038 2.918
|
|---|
| 6522 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 288 CB -0.055 3.515
|
|---|
| 6523 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A PRO 371 CA -0.065 3.525
|
|---|
| 6524 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1FLI.pdbqt #1/A TRP 302 CG -0.089 3.669
|
|---|
| 6525 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 369 CD2 -0.091 3.551
|
|---|
| 6526 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 369 O -0.144 3.384
|
|---|
| 6527 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 288 2HD1 -0.165 2.925
|
|---|
| 6528 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 288 CB -0.166 3.476
|
|---|
| 6529 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 288 HB3 -0.197 2.957
|
|---|
| 6530 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 369 CD2 -0.206 3.666
|
|---|
| 6531 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A TRP 302 CH2 -0.224 3.684
|
|---|
| 6532 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A TRP 302 CZ3 -0.228 3.688
|
|---|
| 6533 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A TRP 302 HH2 -0.228 2.838
|
|---|
| 6534 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A PRO 371 N -0.247 3.632
|
|---|
| 6535 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A TRP 302 CE2 -0.250 3.710
|
|---|
| 6536 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 O 1FLI.pdbqt #1/A TRP 302 HH2 -0.251 2.671
|
|---|
| 6537 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 369 C -0.269 3.729
|
|---|
| 6538 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 O 1FLI.pdbqt #1/A SER 292 CB -0.272 3.392
|
|---|
| 6539 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 288 3HD2 -0.277 2.887
|
|---|
| 6540 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A TRP 302 CD2 -0.286 3.596
|
|---|
| 6541 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 288 CD1 -0.287 3.747
|
|---|
| 6542 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 288 3HD2 -0.291 2.901
|
|---|
| 6543 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 288 CB -0.294 3.604
|
|---|
| 6544 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A TRP 302 CE3 -0.311 3.771
|
|---|
| 6545 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A TRP 302 CZ2 -0.324 3.784
|
|---|
| 6546 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A TRP 302 CE3 -0.330 3.790
|
|---|
| 6547 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 288 2HD1 -0.331 3.091
|
|---|
| 6548 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A PHE 309 HE1 -0.348 3.108
|
|---|
| 6549 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 288 CD1 -0.365 3.825
|
|---|
| 6550 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A TRP 302 CD2 -0.368 3.828
|
|---|
| 6551 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A LEU 288 HB2 -0.373 3.133
|
|---|
| 6552 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A TRP 302 CZ3 -0.388 3.698
|
|---|
| 6553 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 O 1FLI.pdbqt #1/A TRP 302 CH2 -0.390 3.550
|
|---|
| 6554 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 O 1FLI.pdbqt #1/A LEU 288 C -0.393 3.553
|
|---|
| 6555 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1FLI.pdbqt #1/A TRP 302 NE1 -0.396 3.901
|
|---|
| 6556 | 1FLI--WRM-16.result.pdbqt #2.1/? UNL 1 C 1FLI.pdbqt #1/A GLN 370 C -0.400 3.860
|
|---|
| 6557 |
|
|---|
| 6558 |
|
|---|
| 6559 |
|
|---|
| 6560 | 45 contacts
|
|---|
| 6561 |
|
|---|
| 6562 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 6563 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1FLI--
|
|---|
| 6564 | > WRM-16.hbonds.txt
|
|---|
| 6565 |
|
|---|
| 6566 |
|
|---|
| 6567 | Finding intermodel H-bonds
|
|---|
| 6568 | Finding intramodel H-bonds
|
|---|
| 6569 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 6570 | Models used:
|
|---|
| 6571 | 1 1FLI.pdbqt
|
|---|
| 6572 | 2.1 1FLI--WRM-16.result.pdbqt
|
|---|
| 6573 |
|
|---|
| 6574 | 0 H-bonds
|
|---|
| 6575 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 6576 |
|
|---|
| 6577 |
|
|---|
| 6578 |
|
|---|
| 6579 | 0 hydrogen bonds found
|
|---|
| 6580 |
|
|---|
| 6581 | > select :UNL
|
|---|
| 6582 |
|
|---|
| 6583 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 6584 |
|
|---|
| 6585 | > label sel text "Ligand "
|
|---|
| 6586 |
|
|---|
| 6587 | > label height 1
|
|---|
| 6588 |
|
|---|
| 6589 | > ~select
|
|---|
| 6590 |
|
|---|
| 6591 | Nothing selected
|
|---|
| 6592 |
|
|---|
| 6593 | > 2dlabels text "Binding Energy: -7.4 kcal/mol" color red size 18 xpos .03
|
|---|
| 6594 | > ypos .95
|
|---|
| 6595 |
|
|---|
| 6596 | > 2dlabels text "1FLI WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 6597 |
|
|---|
| 6598 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1FLI--
|
|---|
| 6599 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 6600 | > true
|
|---|
| 6601 |
|
|---|
| 6602 | > select :UNL
|
|---|
| 6603 |
|
|---|
| 6604 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 6605 |
|
|---|
| 6606 | > view sel
|
|---|
| 6607 |
|
|---|
| 6608 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1FLI--
|
|---|
| 6609 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 6610 | > true
|
|---|
| 6611 |
|
|---|
| 6612 | > close
|
|---|
| 6613 |
|
|---|
| 6614 | > wait 5
|
|---|
| 6615 |
|
|---|
| 6616 | > set bgColor white
|
|---|
| 6617 |
|
|---|
| 6618 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/5LTY.pdbqt
|
|---|
| 6619 |
|
|---|
| 6620 | Chain information for 5LTY.pdbqt #1
|
|---|
| 6621 | ---
|
|---|
| 6622 | Chain | Description
|
|---|
| 6623 | A B | No description available
|
|---|
| 6624 | E F | No description available
|
|---|
| 6625 | K | No description available
|
|---|
| 6626 | M | No description available
|
|---|
| 6627 |
|
|---|
| 6628 | Opened 5LTY.pdbqt containing 1 structures (4847 atoms, 5029 bonds)
|
|---|
| 6629 |
|
|---|
| 6630 | > wait 5
|
|---|
| 6631 |
|
|---|
| 6632 | > hide surfaces
|
|---|
| 6633 |
|
|---|
| 6634 | > hide atoms
|
|---|
| 6635 |
|
|---|
| 6636 | > show cartoons
|
|---|
| 6637 |
|
|---|
| 6638 | > wait 5
|
|---|
| 6639 |
|
|---|
| 6640 | > addh
|
|---|
| 6641 |
|
|---|
| 6642 | Summary of feedback from adding hydrogens to 5LTY.pdbqt #1
|
|---|
| 6643 | ---
|
|---|
| 6644 | warnings | Not adding hydrogens to /A DT 1 P because it is missing heavy-atom
|
|---|
| 6645 | bond partners
|
|---|
| 6646 | Not adding hydrogens to /B DT 1 P because it is missing heavy-atom bond
|
|---|
| 6647 | partners
|
|---|
| 6648 | Not adding hydrogens to /F DG 19 P because it is missing heavy-atom bond
|
|---|
| 6649 | partners
|
|---|
| 6650 | Not adding hydrogens to /E DG 19 P because it is missing heavy-atom bond
|
|---|
| 6651 | partners
|
|---|
| 6652 | notes | No usable SEQRES records for 5LTY.pdbqt (#1) chain A; guessing termini
|
|---|
| 6653 | instead
|
|---|
| 6654 | No usable SEQRES records for 5LTY.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 6655 | No usable SEQRES records for 5LTY.pdbqt (#1) chain E; guessing termini instead
|
|---|
| 6656 | No usable SEQRES records for 5LTY.pdbqt (#1) chain F; guessing termini instead
|
|---|
| 6657 | No usable SEQRES records for 5LTY.pdbqt (#1) chain K; guessing termini instead
|
|---|
| 6658 | 1 messages similar to the above omitted
|
|---|
| 6659 | Chain-initial residues that are actual N termini: /A DT 1, /B DT 1, /E DG 19,
|
|---|
| 6660 | /F DG 19, /K THR 185, /M LYS 186
|
|---|
| 6661 | Chain-initial residues that are not actual N termini: /A DG 12, /B DG 12, /E
|
|---|
| 6662 | DG 26, /F DG 26
|
|---|
| 6663 | Chain-final residues that are actual C termini: /A DC 18, /B DC 18, /E DA 36,
|
|---|
| 6664 | /F DA 36, /K GLN 255, /M GLN 255
|
|---|
| 6665 | Chain-final residues that are not actual C termini: /A DA 10, /B DA 10, /E DT
|
|---|
| 6666 | 24, /F DT 24
|
|---|
| 6667 | 250 hydrogen bonds
|
|---|
| 6668 | 4 hydrogens added
|
|---|
| 6669 |
|
|---|
| 6670 |
|
|---|
| 6671 | > wait 5
|
|---|
| 6672 |
|
|---|
| 6673 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/5LTY--
|
|---|
| 6674 | > WRM-16.result.pdbqt
|
|---|
| 6675 |
|
|---|
| 6676 | Summary of feedback from opening
|
|---|
| 6677 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/5LTY--WRM-16.result.pdbqt
|
|---|
| 6678 | ---
|
|---|
| 6679 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 6680 | REMARK VINA RESULT: -8.4 0.000 0.000
|
|---|
| 6681 |
|
|---|
| 6682 | Ignored bad PDB record found on line 3
|
|---|
| 6683 | REMARK 5 active torsions:
|
|---|
| 6684 |
|
|---|
| 6685 | Ignored bad PDB record found on line 4
|
|---|
| 6686 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 6687 |
|
|---|
| 6688 | Ignored bad PDB record found on line 5
|
|---|
| 6689 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 6690 |
|
|---|
| 6691 | Ignored bad PDB record found on line 6
|
|---|
| 6692 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 6693 |
|
|---|
| 6694 | 184 messages similar to the above omitted
|
|---|
| 6695 |
|
|---|
| 6696 | Opened 5LTY--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 6697 | bonds)
|
|---|
| 6698 |
|
|---|
| 6699 | > wait 5
|
|---|
| 6700 |
|
|---|
| 6701 | > close #2.2-9
|
|---|
| 6702 |
|
|---|
| 6703 | > wait 5
|
|---|
| 6704 |
|
|---|
| 6705 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 6706 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5LTY--
|
|---|
| 6707 | > WRM-16.contacts.txt
|
|---|
| 6708 |
|
|---|
| 6709 |
|
|---|
| 6710 | Allowed overlap: -0.4
|
|---|
| 6711 | H-bond overlap reduction: 0.4
|
|---|
| 6712 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 6713 | Detect intra-residue contacts: False
|
|---|
| 6714 | Detect intra-molecule contacts: True
|
|---|
| 6715 |
|
|---|
| 6716 | 53 contacts
|
|---|
| 6717 | atom1 atom2 overlap distance
|
|---|
| 6718 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/M LYS 243 HZ2 0.418 2.462
|
|---|
| 6719 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/E DT 27 H73 0.241 2.639
|
|---|
| 6720 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5LTY.pdbqt #1/M ASN 236 HB1 0.235 2.645
|
|---|
| 6721 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/M LYS 243 NZ 0.227 3.278
|
|---|
| 6722 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 O 5LTY.pdbqt #1/E DA 28 H61 0.212 1.808
|
|---|
| 6723 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/M LYS 240 HB2 0.183 2.577
|
|---|
| 6724 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/M ASN 236 HB1 0.168 2.592
|
|---|
| 6725 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 9 H71 0.135 2.625
|
|---|
| 6726 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 8 H71 0.114 2.766
|
|---|
| 6727 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 8 H72 0.090 2.670
|
|---|
| 6728 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/E DA 28 H61 0.080 2.530
|
|---|
| 6729 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/M LYS 240 CB 0.033 3.427
|
|---|
| 6730 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 7 H71 0.003 2.877
|
|---|
| 6731 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/E DA 29 H61 -0.009 2.889
|
|---|
| 6732 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/E DT 27 C7 -0.033 3.613
|
|---|
| 6733 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 O 5LTY.pdbqt #1/E DT 27 H73 -0.045 2.505
|
|---|
| 6734 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 8 H72 -0.046 2.806
|
|---|
| 6735 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 7 H72 -0.051 2.931
|
|---|
| 6736 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/M ASN 236 CB -0.069 3.529
|
|---|
| 6737 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5LTY.pdbqt #1/M ASN 236 CB -0.072 3.652
|
|---|
| 6738 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 7 OP2 -0.079 3.459
|
|---|
| 6739 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 9 C7 -0.099 3.559
|
|---|
| 6740 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/E DT 27 H73 -0.100 2.710
|
|---|
| 6741 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/E DT 27 H73 -0.122 3.002
|
|---|
| 6742 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/M LYS 240 HB2 -0.125 2.735
|
|---|
| 6743 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 7 H72 -0.130 2.740
|
|---|
| 6744 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 7 H72 -0.133 2.743
|
|---|
| 6745 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5LTY.pdbqt #1/M LYS 240 HB2 -0.145 3.025
|
|---|
| 6746 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 8 C7 -0.147 3.727
|
|---|
| 6747 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 7 O4 -0.148 3.508
|
|---|
| 6748 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/E DA 29 N6 -0.149 3.654
|
|---|
| 6749 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 8 C7 -0.153 3.613
|
|---|
| 6750 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 O 5LTY.pdbqt #1/E DA 28 N6 -0.168 2.813
|
|---|
| 6751 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 7 C7 -0.179 3.489
|
|---|
| 6752 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/E DA 28 N6 -0.183 3.418
|
|---|
| 6753 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 7 C7 -0.193 3.503
|
|---|
| 6754 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5LTY.pdbqt #1/B DT 9 C7 -0.198 3.778
|
|---|
| 6755 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 8 C7 -0.209 3.669
|
|---|
| 6756 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5LTY.pdbqt #1/M ASN 236 C -0.248 3.828
|
|---|
| 6757 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/M LYS 240 CG -0.262 3.722
|
|---|
| 6758 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/E DT 27 C7 -0.285 3.595
|
|---|
| 6759 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 7 H71 -0.289 2.899
|
|---|
| 6760 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5LTY.pdbqt #1/M LYS 240 HD2 -0.299 3.179
|
|---|
| 6761 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 8 H72 -0.302 2.912
|
|---|
| 6762 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 8 H71 -0.305 3.185
|
|---|
| 6763 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 7 C7 -0.311 3.891
|
|---|
| 6764 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/M ASN 236 O -0.320 3.560
|
|---|
| 6765 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 O 5LTY.pdbqt #1/E DT 27 C5 -0.325 3.445
|
|---|
| 6766 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/B DT 8 C7 -0.349 3.929
|
|---|
| 6767 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/M LYS 243 HZ3 -0.354 3.234
|
|---|
| 6768 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5LTY.pdbqt #1/M ASN 236 O -0.369 3.729
|
|---|
| 6769 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 O 5LTY.pdbqt #1/E DT 27 C7 -0.383 3.543
|
|---|
| 6770 | 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 C 5LTY.pdbqt #1/M ASN 236 HB1 -0.396 3.006
|
|---|
| 6771 |
|
|---|
| 6772 |
|
|---|
| 6773 |
|
|---|
| 6774 | 53 contacts
|
|---|
| 6775 |
|
|---|
| 6776 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 6777 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5LTY--
|
|---|
| 6778 | > WRM-16.hbonds.txt
|
|---|
| 6779 |
|
|---|
| 6780 |
|
|---|
| 6781 | Finding intermodel H-bonds
|
|---|
| 6782 | Finding intramodel H-bonds
|
|---|
| 6783 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 6784 | Models used:
|
|---|
| 6785 | 1 5LTY.pdbqt
|
|---|
| 6786 | 2.1 5LTY--WRM-16.result.pdbqt
|
|---|
| 6787 |
|
|---|
| 6788 | 3 H-bonds
|
|---|
| 6789 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 6790 | 5LTY.pdbqt #1/E DA 28 N6 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 O 5LTY.pdbqt #1/E DA 28 H61 3.435 2.808
|
|---|
| 6791 | 5LTY.pdbqt #1/E DA 28 N6 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 O 5LTY.pdbqt #1/E DA 28 H61 2.813 1.808
|
|---|
| 6792 | 5LTY.pdbqt #1/E DA 28 N7 5LTY--WRM-16.result.pdbqt #2.1/? UNL 1 O 5LTY.pdbqt #1/E DA 28 H7 3.287 2.424
|
|---|
| 6793 |
|
|---|
| 6794 |
|
|---|
| 6795 |
|
|---|
| 6796 | 3 hydrogen bonds found
|
|---|
| 6797 |
|
|---|
| 6798 | > select :UNL
|
|---|
| 6799 |
|
|---|
| 6800 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 6801 |
|
|---|
| 6802 | > label sel text "Ligand "
|
|---|
| 6803 |
|
|---|
| 6804 | > label height 1
|
|---|
| 6805 |
|
|---|
| 6806 | > ~select
|
|---|
| 6807 |
|
|---|
| 6808 | Nothing selected
|
|---|
| 6809 |
|
|---|
| 6810 | > 2dlabels text "Binding Energy: -8.4 kcal/mol" color red size 18 xpos .03
|
|---|
| 6811 | > ypos .95
|
|---|
| 6812 |
|
|---|
| 6813 | > 2dlabels text "5LTY WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 6814 |
|
|---|
| 6815 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5LTY--
|
|---|
| 6816 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 6817 | > true
|
|---|
| 6818 |
|
|---|
| 6819 | > select :UNL
|
|---|
| 6820 |
|
|---|
| 6821 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 6822 |
|
|---|
| 6823 | > view sel
|
|---|
| 6824 |
|
|---|
| 6825 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5LTY--
|
|---|
| 6826 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 6827 | > true
|
|---|
| 6828 |
|
|---|
| 6829 | > close
|
|---|
| 6830 |
|
|---|
| 6831 | > wait 5
|
|---|
| 6832 |
|
|---|
| 6833 | > set bgColor white
|
|---|
| 6834 |
|
|---|
| 6835 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1JDH.pdbqt
|
|---|
| 6836 |
|
|---|
| 6837 | Chain information for 1JDH.pdbqt #1
|
|---|
| 6838 | ---
|
|---|
| 6839 | Chain | Description
|
|---|
| 6840 | A | No description available
|
|---|
| 6841 | B | No description available
|
|---|
| 6842 |
|
|---|
| 6843 | Opened 1JDH.pdbqt containing 1 structures (8191 atoms, 8243 bonds)
|
|---|
| 6844 |
|
|---|
| 6845 | > wait 5
|
|---|
| 6846 |
|
|---|
| 6847 | > hide surfaces
|
|---|
| 6848 |
|
|---|
| 6849 | > hide atoms
|
|---|
| 6850 |
|
|---|
| 6851 | > show cartoons
|
|---|
| 6852 |
|
|---|
| 6853 | > wait 5
|
|---|
| 6854 |
|
|---|
| 6855 | > addh
|
|---|
| 6856 |
|
|---|
| 6857 | Summary of feedback from adding hydrogens to 1JDH.pdbqt #1
|
|---|
| 6858 | ---
|
|---|
| 6859 | warnings | Not adding hydrogens to /A ILE 140 CB because it is missing heavy-
|
|---|
| 6860 | atom bond partners
|
|---|
| 6861 | Not adding hydrogens to /A ARG 151 CB because it is missing heavy-atom bond
|
|---|
| 6862 | partners
|
|---|
| 6863 | Not adding hydrogens to /A LYS 158 CB because it is missing heavy-atom bond
|
|---|
| 6864 | partners
|
|---|
| 6865 | Not adding hydrogens to /A GLU 163 CB because it is missing heavy-atom bond
|
|---|
| 6866 | partners
|
|---|
| 6867 | Not adding hydrogens to /A GLN 177 CB because it is missing heavy-atom bond
|
|---|
| 6868 | partners
|
|---|
| 6869 | 28 messages similar to the above omitted
|
|---|
| 6870 | notes | No usable SEQRES records for 1JDH.pdbqt (#1) chain A; guessing termini
|
|---|
| 6871 | instead
|
|---|
| 6872 | No usable SEQRES records for 1JDH.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 6873 | Chain-initial residues that are actual N termini: /A ALA 135, /B LEU 12
|
|---|
| 6874 | Chain-initial residues that are not actual N termini: /A ARG 151, /A PHE 560
|
|---|
| 6875 | Chain-final residues that are actual C termini: /A SER 663, /B VAL 49
|
|---|
| 6876 | Chain-final residues that are not actual C termini: /A ILE 140, /A GLN 548
|
|---|
| 6877 | 502 hydrogen bonds
|
|---|
| 6878 | Adding 'H' to /A ARG 151
|
|---|
| 6879 | Adding 'H' to /A PHE 560
|
|---|
| 6880 | /A ILE 140 is not terminus, removing H atom from 'C'
|
|---|
| 6881 | /A GLN 548 is not terminus, removing H atom from 'C'
|
|---|
| 6882 | 5 hydrogens added
|
|---|
| 6883 |
|
|---|
| 6884 |
|
|---|
| 6885 | > wait 5
|
|---|
| 6886 |
|
|---|
| 6887 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1JDH--
|
|---|
| 6888 | > WRM-16.result.pdbqt
|
|---|
| 6889 |
|
|---|
| 6890 | Summary of feedback from opening
|
|---|
| 6891 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1JDH--WRM-16.result.pdbqt
|
|---|
| 6892 | ---
|
|---|
| 6893 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 6894 | REMARK VINA RESULT: -6.7 0.000 0.000
|
|---|
| 6895 |
|
|---|
| 6896 | Ignored bad PDB record found on line 3
|
|---|
| 6897 | REMARK 5 active torsions:
|
|---|
| 6898 |
|
|---|
| 6899 | Ignored bad PDB record found on line 4
|
|---|
| 6900 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 6901 |
|
|---|
| 6902 | Ignored bad PDB record found on line 5
|
|---|
| 6903 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 6904 |
|
|---|
| 6905 | Ignored bad PDB record found on line 6
|
|---|
| 6906 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 6907 |
|
|---|
| 6908 | 184 messages similar to the above omitted
|
|---|
| 6909 |
|
|---|
| 6910 | Opened 1JDH--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 6911 | bonds)
|
|---|
| 6912 |
|
|---|
| 6913 | > wait 5
|
|---|
| 6914 |
|
|---|
| 6915 | > close #2.2-9
|
|---|
| 6916 |
|
|---|
| 6917 | > wait 5
|
|---|
| 6918 |
|
|---|
| 6919 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 6920 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1JDH--
|
|---|
| 6921 | > WRM-16.contacts.txt
|
|---|
| 6922 |
|
|---|
| 6923 |
|
|---|
| 6924 | Allowed overlap: -0.4
|
|---|
| 6925 | H-bond overlap reduction: 0.4
|
|---|
| 6926 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 6927 | Detect intra-residue contacts: False
|
|---|
| 6928 | Detect intra-molecule contacts: True
|
|---|
| 6929 |
|
|---|
| 6930 | 49 contacts
|
|---|
| 6931 | atom1 atom2 overlap distance
|
|---|
| 6932 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A VAL 168 2HG1 0.358 2.522
|
|---|
| 6933 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ARG 200 HE 0.338 2.542
|
|---|
| 6934 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 O 1JDH.pdbqt #1/A ARG 200 HE 0.255 1.805
|
|---|
| 6935 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A GLU 163 HA 0.243 2.517
|
|---|
| 6936 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1JDH.pdbqt #1/A GLU 163 HA 0.123 2.757
|
|---|
| 6937 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 O 1JDH.pdbqt #1/A ARG 200 HB2 0.103 2.357
|
|---|
| 6938 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A VAL 168 3HG2 0.097 2.783
|
|---|
| 6939 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ARG 200 HB2 0.055 2.555
|
|---|
| 6940 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A VAL 168 CG1 0.046 3.534
|
|---|
| 6941 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1JDH.pdbqt #1/A GLU 163 CA 0.013 3.567
|
|---|
| 6942 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ARG 200 NE 0.003 3.502
|
|---|
| 6943 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1JDH.pdbqt #1/A GLU 163 CB -0.018 3.598
|
|---|
| 6944 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 O 1JDH.pdbqt #1/A THR 201 HA -0.027 2.487
|
|---|
| 6945 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 O 1JDH.pdbqt #1/A ARG 200 CB -0.038 3.198
|
|---|
| 6946 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ARG 200 2HH2 -0.088 2.968
|
|---|
| 6947 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ASN 204 HB1 -0.090 2.850
|
|---|
| 6948 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ASN 204 ND2 -0.106 3.611
|
|---|
| 6949 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A GLN 165 1HE2 -0.115 2.995
|
|---|
| 6950 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 O 1JDH.pdbqt #1/A ARG 200 NE -0.118 2.803
|
|---|
| 6951 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 O 1JDH.pdbqt #1/A ASN 161 HA -0.118 2.538
|
|---|
| 6952 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ASN 204 1HD2 -0.126 2.736
|
|---|
| 6953 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A VAL 168 CG2 -0.146 3.726
|
|---|
| 6954 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ARG 200 HB2 -0.155 3.035
|
|---|
| 6955 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A GLU 163 CA -0.159 3.619
|
|---|
| 6956 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A GLU 163 HA -0.171 2.781
|
|---|
| 6957 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ARG 200 CB -0.177 3.487
|
|---|
| 6958 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ASN 204 CB -0.204 3.664
|
|---|
| 6959 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1JDH.pdbqt #1/A GLU 163 HB2 -0.206 3.086
|
|---|
| 6960 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ASN 204 1HD2 -0.213 2.823
|
|---|
| 6961 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 O 1JDH.pdbqt #1/A THR 201 OG1 -0.218 2.738
|
|---|
| 6962 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ASP 162 O -0.235 3.475
|
|---|
| 6963 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ASN 204 CB -0.251 3.561
|
|---|
| 6964 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ARG 200 NH2 -0.267 3.772
|
|---|
| 6965 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 O 1JDH.pdbqt #1/A ASN 161 CA -0.284 3.404
|
|---|
| 6966 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A GLN 165 OE1 -0.287 3.647
|
|---|
| 6967 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ARG 200 HE -0.295 3.175
|
|---|
| 6968 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ASN 161 O -0.303 3.543
|
|---|
| 6969 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ASN 204 ND2 -0.310 3.545
|
|---|
| 6970 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 O 1JDH.pdbqt #1/A ARG 200 CZ -0.336 3.496
|
|---|
| 6971 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ASN 204 HB1 -0.340 2.950
|
|---|
| 6972 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ARG 200 HE -0.356 2.966
|
|---|
| 6973 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1JDH.pdbqt #1/A GLU 163 O -0.363 3.723
|
|---|
| 6974 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A LEU 160 O -0.365 3.725
|
|---|
| 6975 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ASN 204 HB1 -0.368 3.128
|
|---|
| 6976 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ASN 204 ND2 -0.369 3.604
|
|---|
| 6977 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A THR 201 2HG2 -0.380 3.260
|
|---|
| 6978 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 O 1JDH.pdbqt #1/A THR 201 CA -0.385 3.545
|
|---|
| 6979 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 C 1JDH.pdbqt #1/A ARG 200 CB -0.389 3.969
|
|---|
| 6980 | 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 O 1JDH.pdbqt #1/A ARG 200 2HH2 -0.395 2.415
|
|---|
| 6981 |
|
|---|
| 6982 |
|
|---|
| 6983 |
|
|---|
| 6984 | 49 contacts
|
|---|
| 6985 |
|
|---|
| 6986 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 6987 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1JDH--
|
|---|
| 6988 | > WRM-16.hbonds.txt
|
|---|
| 6989 |
|
|---|
| 6990 |
|
|---|
| 6991 | Finding intermodel H-bonds
|
|---|
| 6992 | Finding intramodel H-bonds
|
|---|
| 6993 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 6994 | Models used:
|
|---|
| 6995 | 1 1JDH.pdbqt
|
|---|
| 6996 | 2.1 1JDH--WRM-16.result.pdbqt
|
|---|
| 6997 |
|
|---|
| 6998 | 4 H-bonds
|
|---|
| 6999 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 7000 | 1JDH.pdbqt #1/A ASN 161 ND2 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 O 1JDH.pdbqt #1/A ASN 161 1HD2 3.118 2.516
|
|---|
| 7001 | 1JDH.pdbqt #1/A ARG 200 NE 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 O 1JDH.pdbqt #1/A ARG 200 HE 2.803 1.805
|
|---|
| 7002 | 1JDH.pdbqt #1/A ARG 200 NH2 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 O 1JDH.pdbqt #1/A ARG 200 2HH2 3.325 2.546
|
|---|
| 7003 | 1JDH.pdbqt #1/A ARG 200 NH2 1JDH--WRM-16.result.pdbqt #2.1/? UNL 1 O 1JDH.pdbqt #1/A ARG 200 2HH2 3.343 2.415
|
|---|
| 7004 |
|
|---|
| 7005 |
|
|---|
| 7006 |
|
|---|
| 7007 | 4 hydrogen bonds found
|
|---|
| 7008 |
|
|---|
| 7009 | > select :UNL
|
|---|
| 7010 |
|
|---|
| 7011 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 7012 |
|
|---|
| 7013 | > label sel text "Ligand "
|
|---|
| 7014 |
|
|---|
| 7015 | > label height 1
|
|---|
| 7016 |
|
|---|
| 7017 | > ~select
|
|---|
| 7018 |
|
|---|
| 7019 | Nothing selected
|
|---|
| 7020 |
|
|---|
| 7021 | > 2dlabels text "Binding Energy: -6.7 kcal/mol" color red size 18 xpos .03
|
|---|
| 7022 | > ypos .95
|
|---|
| 7023 |
|
|---|
| 7024 | > 2dlabels text "1JDH WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 7025 |
|
|---|
| 7026 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1JDH--
|
|---|
| 7027 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 7028 | > true
|
|---|
| 7029 |
|
|---|
| 7030 | > select :UNL
|
|---|
| 7031 |
|
|---|
| 7032 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 7033 |
|
|---|
| 7034 | > view sel
|
|---|
| 7035 |
|
|---|
| 7036 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1JDH--
|
|---|
| 7037 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 7038 | > true
|
|---|
| 7039 |
|
|---|
| 7040 | > close
|
|---|
| 7041 |
|
|---|
| 7042 | > wait 5
|
|---|
| 7043 |
|
|---|
| 7044 | > set bgColor white
|
|---|
| 7045 |
|
|---|
| 7046 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/6LZP.pdbqt
|
|---|
| 7047 |
|
|---|
| 7048 | Chain information for 6LZP.pdbqt #1
|
|---|
| 7049 | ---
|
|---|
| 7050 | Chain | Description
|
|---|
| 7051 | A | No description available
|
|---|
| 7052 |
|
|---|
| 7053 | Opened 6LZP.pdbqt containing 1 structures (1381 atoms, 1395 bonds)
|
|---|
| 7054 |
|
|---|
| 7055 | > wait 5
|
|---|
| 7056 |
|
|---|
| 7057 | > hide surfaces
|
|---|
| 7058 |
|
|---|
| 7059 | > hide atoms
|
|---|
| 7060 |
|
|---|
| 7061 | > show cartoons
|
|---|
| 7062 |
|
|---|
| 7063 | > wait 5
|
|---|
| 7064 |
|
|---|
| 7065 | > addh
|
|---|
| 7066 |
|
|---|
| 7067 | Summary of feedback from adding hydrogens to 6LZP.pdbqt #1
|
|---|
| 7068 | ---
|
|---|
| 7069 | notes | No usable SEQRES records for 6LZP.pdbqt (#1) chain A; guessing termini
|
|---|
| 7070 | instead
|
|---|
| 7071 | Chain-initial residues that are actual N termini: /A HIS 171
|
|---|
| 7072 | Chain-initial residues that are not actual N termini:
|
|---|
| 7073 | Chain-final residues that are actual C termini: /A SER 258
|
|---|
| 7074 | Chain-final residues that are not actual C termini:
|
|---|
| 7075 | 35 hydrogen bonds
|
|---|
| 7076 | 1 hydrogens added
|
|---|
| 7077 |
|
|---|
| 7078 |
|
|---|
| 7079 | > wait 5
|
|---|
| 7080 |
|
|---|
| 7081 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/6LZP--
|
|---|
| 7082 | > WRM-16.result.pdbqt
|
|---|
| 7083 |
|
|---|
| 7084 | Summary of feedback from opening
|
|---|
| 7085 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/6LZP--WRM-16.result.pdbqt
|
|---|
| 7086 | ---
|
|---|
| 7087 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 7088 | REMARK VINA RESULT: -6.5 0.000 0.000
|
|---|
| 7089 |
|
|---|
| 7090 | Ignored bad PDB record found on line 3
|
|---|
| 7091 | REMARK 5 active torsions:
|
|---|
| 7092 |
|
|---|
| 7093 | Ignored bad PDB record found on line 4
|
|---|
| 7094 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 7095 |
|
|---|
| 7096 | Ignored bad PDB record found on line 5
|
|---|
| 7097 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 7098 |
|
|---|
| 7099 | Ignored bad PDB record found on line 6
|
|---|
| 7100 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 7101 |
|
|---|
| 7102 | 184 messages similar to the above omitted
|
|---|
| 7103 |
|
|---|
| 7104 | Opened 6LZP--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 7105 | bonds)
|
|---|
| 7106 |
|
|---|
| 7107 | > wait 5
|
|---|
| 7108 |
|
|---|
| 7109 | > close #2.2-9
|
|---|
| 7110 |
|
|---|
| 7111 | > wait 5
|
|---|
| 7112 |
|
|---|
| 7113 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 7114 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/6LZP--
|
|---|
| 7115 | > WRM-16.contacts.txt
|
|---|
| 7116 |
|
|---|
| 7117 |
|
|---|
| 7118 | Allowed overlap: -0.4
|
|---|
| 7119 | H-bond overlap reduction: 0.4
|
|---|
| 7120 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 7121 | Detect intra-residue contacts: False
|
|---|
| 7122 | Detect intra-molecule contacts: True
|
|---|
| 7123 |
|
|---|
| 7124 | 42 contacts
|
|---|
| 7125 | atom1 atom2 overlap distance
|
|---|
| 7126 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LZP.pdbqt #1/A TRP 206 HE3 0.364 2.516
|
|---|
| 7127 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A MET 213 HG2 0.319 2.441
|
|---|
| 7128 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LZP.pdbqt #1/A PHE 204 HE1 0.260 2.620
|
|---|
| 7129 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LZP.pdbqt #1/A TRP 206 CE3 0.181 3.399
|
|---|
| 7130 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LZP.pdbqt #1/A PRO 215 HA 0.168 2.712
|
|---|
| 7131 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A PHE 218 HE2 0.150 2.460
|
|---|
| 7132 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LZP.pdbqt #1/A PRO 215 CA 0.145 3.435
|
|---|
| 7133 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LZP.pdbqt #1/A PHE 204 CE1 0.125 3.455
|
|---|
| 7134 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LZP.pdbqt #1/A PRO 215 N 0.050 3.455
|
|---|
| 7135 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A MET 213 HE1 0.040 2.840
|
|---|
| 7136 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 O 6LZP.pdbqt #1/A THR 205 H 0.034 1.986
|
|---|
| 7137 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A THR 205 H -0.009 2.619
|
|---|
| 7138 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A PHE 204 HE1 -0.027 2.637
|
|---|
| 7139 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A MET 213 CG -0.029 3.489
|
|---|
| 7140 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LZP.pdbqt #1/A THR 214 C -0.067 3.647
|
|---|
| 7141 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A THR 205 HG1 -0.077 2.687
|
|---|
| 7142 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A PHE 204 HB2 -0.091 2.701
|
|---|
| 7143 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A MET 213 HG2 -0.093 2.703
|
|---|
| 7144 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A PHE 218 HB2 -0.114 2.874
|
|---|
| 7145 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A PHE 218 HE2 -0.120 2.880
|
|---|
| 7146 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LZP.pdbqt #1/A TRP 206 CZ3 -0.132 3.712
|
|---|
| 7147 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 O 6LZP.pdbqt #1/A THR 205 HG1 -0.139 2.159
|
|---|
| 7148 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A MET 213 HG2 -0.146 2.906
|
|---|
| 7149 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A PHE 218 CE2 -0.174 3.484
|
|---|
| 7150 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 O 6LZP.pdbqt #1/A THR 205 O -0.176 3.116
|
|---|
| 7151 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A PHE 218 HE2 -0.179 2.789
|
|---|
| 7152 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A PHE 204 HE1 -0.191 2.951
|
|---|
| 7153 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A MET 213 CE -0.193 3.773
|
|---|
| 7154 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A PHE 204 CE1 -0.195 3.505
|
|---|
| 7155 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A PHE 218 HE2 -0.234 2.844
|
|---|
| 7156 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A PHE 204 CB -0.256 3.836
|
|---|
| 7157 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A PHE 218 CE2 -0.256 3.566
|
|---|
| 7158 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A THR 205 N -0.271 3.506
|
|---|
| 7159 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A TRP 206 HE3 -0.271 3.031
|
|---|
| 7160 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A PHE 218 CB -0.294 3.754
|
|---|
| 7161 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A MET 213 CG -0.298 3.758
|
|---|
| 7162 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LZP.pdbqt #1/A PRO 215 CB -0.314 3.894
|
|---|
| 7163 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 O 6LZP.pdbqt #1/A THR 205 N -0.320 2.965
|
|---|
| 7164 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LZP.pdbqt #1/A TRP 206 HZ3 -0.324 3.204
|
|---|
| 7165 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 6LZP.pdbqt #1/A PHE 204 CZ -0.337 3.917
|
|---|
| 7166 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A THR 205 OG1 -0.354 3.464
|
|---|
| 7167 | 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 C 6LZP.pdbqt #1/A PHE 218 CE2 -0.361 3.821
|
|---|
| 7168 |
|
|---|
| 7169 |
|
|---|
| 7170 |
|
|---|
| 7171 | 42 contacts
|
|---|
| 7172 |
|
|---|
| 7173 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 7174 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/6LZP--
|
|---|
| 7175 | > WRM-16.hbonds.txt
|
|---|
| 7176 |
|
|---|
| 7177 |
|
|---|
| 7178 | Finding intermodel H-bonds
|
|---|
| 7179 | Finding intramodel H-bonds
|
|---|
| 7180 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 7181 | Models used:
|
|---|
| 7182 | 1 6LZP.pdbqt
|
|---|
| 7183 | 2.1 6LZP--WRM-16.result.pdbqt
|
|---|
| 7184 |
|
|---|
| 7185 | 2 H-bonds
|
|---|
| 7186 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 7187 | 6LZP.pdbqt #1/A THR 205 N 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 O 6LZP.pdbqt #1/A THR 205 H 2.965 1.986
|
|---|
| 7188 | 6LZP.pdbqt #1/A THR 205 OG1 6LZP--WRM-16.result.pdbqt #2.1/? UNL 1 O 6LZP.pdbqt #1/A THR 205 HG1 3.071 2.159
|
|---|
| 7189 |
|
|---|
| 7190 |
|
|---|
| 7191 |
|
|---|
| 7192 | 2 hydrogen bonds found
|
|---|
| 7193 |
|
|---|
| 7194 | > select :UNL
|
|---|
| 7195 |
|
|---|
| 7196 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 7197 |
|
|---|
| 7198 | > label sel text "Ligand "
|
|---|
| 7199 |
|
|---|
| 7200 | > label height 1
|
|---|
| 7201 |
|
|---|
| 7202 | > ~select
|
|---|
| 7203 |
|
|---|
| 7204 | Nothing selected
|
|---|
| 7205 |
|
|---|
| 7206 | > 2dlabels text "Binding Energy: -6.5 kcal/mol" color red size 18 xpos .03
|
|---|
| 7207 | > ypos .95
|
|---|
| 7208 |
|
|---|
| 7209 | > 2dlabels text "6LZP WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 7210 |
|
|---|
| 7211 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/6LZP--
|
|---|
| 7212 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 7213 | > true
|
|---|
| 7214 |
|
|---|
| 7215 | > select :UNL
|
|---|
| 7216 |
|
|---|
| 7217 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 7218 |
|
|---|
| 7219 | > view sel
|
|---|
| 7220 |
|
|---|
| 7221 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/6LZP--
|
|---|
| 7222 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 7223 | > true
|
|---|
| 7224 |
|
|---|
| 7225 | > close
|
|---|
| 7226 |
|
|---|
| 7227 | > wait 5
|
|---|
| 7228 |
|
|---|
| 7229 | > set bgColor white
|
|---|
| 7230 |
|
|---|
| 7231 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/2CS1.pdbqt
|
|---|
| 7232 |
|
|---|
| 7233 | Chain information for 2CS1.pdbqt #1
|
|---|
| 7234 | ---
|
|---|
| 7235 | Chain | Description
|
|---|
| 7236 | A | No description available
|
|---|
| 7237 |
|
|---|
| 7238 | Opened 2CS1.pdbqt containing 1 structures (1441 atoms, 1451 bonds)
|
|---|
| 7239 |
|
|---|
| 7240 | > wait 5
|
|---|
| 7241 |
|
|---|
| 7242 | > hide surfaces
|
|---|
| 7243 |
|
|---|
| 7244 | > hide atoms
|
|---|
| 7245 |
|
|---|
| 7246 | > show cartoons
|
|---|
| 7247 |
|
|---|
| 7248 | > wait 5
|
|---|
| 7249 |
|
|---|
| 7250 | > addh
|
|---|
| 7251 |
|
|---|
| 7252 | Summary of feedback from adding hydrogens to 2CS1.pdbqt #1
|
|---|
| 7253 | ---
|
|---|
| 7254 | notes | No usable SEQRES records for 2CS1.pdbqt (#1) chain A; guessing termini
|
|---|
| 7255 | instead
|
|---|
| 7256 | Chain-initial residues that are actual N termini: /A GLY 1
|
|---|
| 7257 | Chain-initial residues that are not actual N termini:
|
|---|
| 7258 | Chain-final residues that are actual C termini: /A GLY 92
|
|---|
| 7259 | Chain-final residues that are not actual C termini:
|
|---|
| 7260 | 43 hydrogen bonds
|
|---|
| 7261 | 1 hydrogens added
|
|---|
| 7262 |
|
|---|
| 7263 |
|
|---|
| 7264 | > wait 5
|
|---|
| 7265 |
|
|---|
| 7266 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2CS1--
|
|---|
| 7267 | > WRM-16.result.pdbqt
|
|---|
| 7268 |
|
|---|
| 7269 | Summary of feedback from opening
|
|---|
| 7270 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2CS1--WRM-16.result.pdbqt
|
|---|
| 7271 | ---
|
|---|
| 7272 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 7273 | REMARK VINA RESULT: -7.0 0.000 0.000
|
|---|
| 7274 |
|
|---|
| 7275 | Ignored bad PDB record found on line 3
|
|---|
| 7276 | REMARK 5 active torsions:
|
|---|
| 7277 |
|
|---|
| 7278 | Ignored bad PDB record found on line 4
|
|---|
| 7279 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 7280 |
|
|---|
| 7281 | Ignored bad PDB record found on line 5
|
|---|
| 7282 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 7283 |
|
|---|
| 7284 | Ignored bad PDB record found on line 6
|
|---|
| 7285 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 7286 |
|
|---|
| 7287 | 184 messages similar to the above omitted
|
|---|
| 7288 |
|
|---|
| 7289 | Opened 2CS1--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 7290 | bonds)
|
|---|
| 7291 |
|
|---|
| 7292 | > wait 5
|
|---|
| 7293 |
|
|---|
| 7294 | > close #2.2-9
|
|---|
| 7295 |
|
|---|
| 7296 | > wait 5
|
|---|
| 7297 |
|
|---|
| 7298 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 7299 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2CS1--
|
|---|
| 7300 | > WRM-16.contacts.txt
|
|---|
| 7301 |
|
|---|
| 7302 |
|
|---|
| 7303 | Allowed overlap: -0.4
|
|---|
| 7304 | H-bond overlap reduction: 0.4
|
|---|
| 7305 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 7306 | Detect intra-residue contacts: False
|
|---|
| 7307 | Detect intra-molecule contacts: True
|
|---|
| 7308 |
|
|---|
| 7309 | 50 contacts
|
|---|
| 7310 | atom1 atom2 overlap distance
|
|---|
| 7311 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A ALA 14 HB2 0.371 2.389
|
|---|
| 7312 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 O 2CS1.pdbqt #1/A SER 13 HG 0.226 1.834
|
|---|
| 7313 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A ALA 61 HB1 0.195 2.685
|
|---|
| 7314 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A PRO 11 HD2 0.150 2.610
|
|---|
| 7315 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A GLU 58 HG2 0.131 2.629
|
|---|
| 7316 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A PRO 11 HG2 0.080 2.680
|
|---|
| 7317 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A LYS 10 HD2 0.072 2.688
|
|---|
| 7318 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A ALA 14 CB 0.013 3.447
|
|---|
| 7319 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A LEU 65 CD1 -0.019 3.599
|
|---|
| 7320 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A SER 13 HG -0.028 2.908
|
|---|
| 7321 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A GLU 58 HG2 -0.041 2.801
|
|---|
| 7322 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A LEU 65 3HD1 -0.049 2.929
|
|---|
| 7323 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A SER 13 HG -0.068 2.948
|
|---|
| 7324 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A SER 13 OG -0.074 3.454
|
|---|
| 7325 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A TYR 68 CE2 -0.090 3.550
|
|---|
| 7326 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A PRO 11 CG -0.104 3.564
|
|---|
| 7327 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A PRO 11 CD -0.117 3.577
|
|---|
| 7328 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A SER 13 HG -0.124 2.734
|
|---|
| 7329 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2CS1.pdbqt #1/A LYS 54 HZ1 -0.129 3.009
|
|---|
| 7330 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 O 2CS1.pdbqt #1/A SER 13 OG -0.138 2.698
|
|---|
| 7331 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A ALA 61 CB -0.158 3.738
|
|---|
| 7332 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A GLU 58 CG -0.166 3.626
|
|---|
| 7333 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A LYS 10 CD -0.172 3.632
|
|---|
| 7334 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2CS1.pdbqt #1/A LYS 54 HD3 -0.195 3.075
|
|---|
| 7335 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A GLY 1 HN -0.208 2.968
|
|---|
| 7336 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A ALA 61 O -0.211 3.571
|
|---|
| 7337 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A LEU 65 CD1 -0.220 3.530
|
|---|
| 7338 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A GLU 58 OE1 -0.227 3.467
|
|---|
| 7339 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A PRO 11 HG2 -0.229 3.109
|
|---|
| 7340 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A TYR 68 CD2 -0.237 3.697
|
|---|
| 7341 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 O 2CS1.pdbqt #1/A ALA 61 HB3 -0.242 2.662
|
|---|
| 7342 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A GLY 1 HA2 -0.267 3.147
|
|---|
| 7343 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A GLU 58 CG -0.272 3.732
|
|---|
| 7344 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A GLU 58 OE1 -0.276 3.516
|
|---|
| 7345 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A SER 13 HA -0.296 3.176
|
|---|
| 7346 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A PRO 11 HD2 -0.304 3.064
|
|---|
| 7347 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A LEU 65 2HD1 -0.327 2.937
|
|---|
| 7348 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A PRO 11 CD -0.330 3.790
|
|---|
| 7349 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A LYS 10 HB3 -0.331 3.091
|
|---|
| 7350 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A SER 13 CB -0.332 3.912
|
|---|
| 7351 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A LEU 65 CD1 -0.334 3.644
|
|---|
| 7352 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A TYR 68 CZ -0.337 3.797
|
|---|
| 7353 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2CS1.pdbqt #1/A LYS 54 NZ -0.359 3.864
|
|---|
| 7354 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A SER 13 OG -0.373 3.483
|
|---|
| 7355 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A LYS 10 HD2 -0.378 3.138
|
|---|
| 7356 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A GLY 1 N -0.379 3.764
|
|---|
| 7357 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A PRO 11 CG -0.380 3.840
|
|---|
| 7358 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A TRP 46 HZ2 -0.386 3.146
|
|---|
| 7359 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 O 2CS1.pdbqt #1/A ALA 61 CB -0.386 3.506
|
|---|
| 7360 | 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 C 2CS1.pdbqt #1/A LEU 65 CD2 -0.388 3.968
|
|---|
| 7361 |
|
|---|
| 7362 |
|
|---|
| 7363 |
|
|---|
| 7364 | 50 contacts
|
|---|
| 7365 |
|
|---|
| 7366 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 7367 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2CS1--
|
|---|
| 7368 | > WRM-16.hbonds.txt
|
|---|
| 7369 |
|
|---|
| 7370 |
|
|---|
| 7371 | Finding intermodel H-bonds
|
|---|
| 7372 | Finding intramodel H-bonds
|
|---|
| 7373 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 7374 | Models used:
|
|---|
| 7375 | 1 2CS1.pdbqt
|
|---|
| 7376 | 2.1 2CS1--WRM-16.result.pdbqt
|
|---|
| 7377 |
|
|---|
| 7378 | 1 H-bonds
|
|---|
| 7379 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 7380 | 2CS1.pdbqt #1/A SER 13 OG 2CS1--WRM-16.result.pdbqt #2.1/? UNL 1 O 2CS1.pdbqt #1/A SER 13 HG 2.698 1.834
|
|---|
| 7381 |
|
|---|
| 7382 |
|
|---|
| 7383 |
|
|---|
| 7384 | 1 hydrogen bonds found
|
|---|
| 7385 |
|
|---|
| 7386 | > select :UNL
|
|---|
| 7387 |
|
|---|
| 7388 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 7389 |
|
|---|
| 7390 | > label sel text "Ligand "
|
|---|
| 7391 |
|
|---|
| 7392 | > label height 1
|
|---|
| 7393 |
|
|---|
| 7394 | > ~select
|
|---|
| 7395 |
|
|---|
| 7396 | Nothing selected
|
|---|
| 7397 |
|
|---|
| 7398 | > 2dlabels text "Binding Energy: -7.0 kcal/mol" color red size 18 xpos .03
|
|---|
| 7399 | > ypos .95
|
|---|
| 7400 |
|
|---|
| 7401 | > 2dlabels text "2CS1 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 7402 |
|
|---|
| 7403 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2CS1--
|
|---|
| 7404 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 7405 | > true
|
|---|
| 7406 |
|
|---|
| 7407 | > select :UNL
|
|---|
| 7408 |
|
|---|
| 7409 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 7410 |
|
|---|
| 7411 | > view sel
|
|---|
| 7412 |
|
|---|
| 7413 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2CS1--
|
|---|
| 7414 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 7415 | > true
|
|---|
| 7416 |
|
|---|
| 7417 | > close
|
|---|
| 7418 |
|
|---|
| 7419 | > wait 5
|
|---|
| 7420 |
|
|---|
| 7421 | > set bgColor white
|
|---|
| 7422 |
|
|---|
| 7423 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/2GU8.pdbqt
|
|---|
| 7424 |
|
|---|
| 7425 | Chain information for 2GU8.pdbqt #1
|
|---|
| 7426 | ---
|
|---|
| 7427 | Chain | Description
|
|---|
| 7428 | A | No description available
|
|---|
| 7429 | C | No description available
|
|---|
| 7430 |
|
|---|
| 7431 | Opened 2GU8.pdbqt containing 1 structures (5803 atoms, 5874 bonds)
|
|---|
| 7432 |
|
|---|
| 7433 | > wait 5
|
|---|
| 7434 |
|
|---|
| 7435 | > hide surfaces
|
|---|
| 7436 |
|
|---|
| 7437 | > hide atoms
|
|---|
| 7438 |
|
|---|
| 7439 | > show cartoons
|
|---|
| 7440 |
|
|---|
| 7441 | > wait 5
|
|---|
| 7442 |
|
|---|
| 7443 | > addh
|
|---|
| 7444 |
|
|---|
| 7445 | Summary of feedback from adding hydrogens to 2GU8.pdbqt #1
|
|---|
| 7446 | ---
|
|---|
| 7447 | warnings | Not adding hydrogens to /A VAL 15 CB because it is missing heavy-
|
|---|
| 7448 | atom bond partners
|
|---|
| 7449 | Not adding hydrogens to /A LYS 16 CB because it is missing heavy-atom bond
|
|---|
| 7450 | partners
|
|---|
| 7451 | Not adding hydrogens to /A GLU 17 CB because it is missing heavy-atom bond
|
|---|
| 7452 | partners
|
|---|
| 7453 | Not adding hydrogens to /A LYS 21 CB because it is missing heavy-atom bond
|
|---|
| 7454 | partners
|
|---|
| 7455 | notes | No usable SEQRES records for 2GU8.pdbqt (#1) chain A; guessing termini
|
|---|
| 7456 | instead
|
|---|
| 7457 | No usable SEQRES records for 2GU8.pdbqt (#1) chain C; guessing termini instead
|
|---|
| 7458 | Chain-initial residues that are actual N termini: /A SER 14, /C THR 505
|
|---|
| 7459 | Chain-initial residues that are not actual N termini: /A LEU 198, /A ILE 339
|
|---|
| 7460 | Chain-final residues that are actual C termini: /A PHE 350, /C ASP 524
|
|---|
| 7461 | Chain-final residues that are not actual C termini: /A TRP 196, /A VAL 337
|
|---|
| 7462 | 290 hydrogen bonds
|
|---|
| 7463 | Adding 'H' to /A LEU 198
|
|---|
| 7464 | Adding 'H' to /A ILE 339
|
|---|
| 7465 | /A TRP 196 is not terminus, removing H atom from 'C'
|
|---|
| 7466 | /A VAL 337 is not terminus, removing H atom from 'C'
|
|---|
| 7467 | -2 hydrogens added
|
|---|
| 7468 |
|
|---|
| 7469 |
|
|---|
| 7470 | > wait 5
|
|---|
| 7471 |
|
|---|
| 7472 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2GU8--
|
|---|
| 7473 | > WRM-16.result.pdbqt
|
|---|
| 7474 |
|
|---|
| 7475 | Summary of feedback from opening
|
|---|
| 7476 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2GU8--WRM-16.result.pdbqt
|
|---|
| 7477 | ---
|
|---|
| 7478 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 7479 | REMARK VINA RESULT: -8.1 0.000 0.000
|
|---|
| 7480 |
|
|---|
| 7481 | Ignored bad PDB record found on line 3
|
|---|
| 7482 | REMARK 5 active torsions:
|
|---|
| 7483 |
|
|---|
| 7484 | Ignored bad PDB record found on line 4
|
|---|
| 7485 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 7486 |
|
|---|
| 7487 | Ignored bad PDB record found on line 5
|
|---|
| 7488 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 7489 |
|
|---|
| 7490 | Ignored bad PDB record found on line 6
|
|---|
| 7491 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 7492 |
|
|---|
| 7493 | 184 messages similar to the above omitted
|
|---|
| 7494 |
|
|---|
| 7495 | Opened 2GU8--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 7496 | bonds)
|
|---|
| 7497 |
|
|---|
| 7498 | > wait 5
|
|---|
| 7499 |
|
|---|
| 7500 | > close #2.2-9
|
|---|
| 7501 |
|
|---|
| 7502 | > wait 5
|
|---|
| 7503 |
|
|---|
| 7504 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 7505 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2GU8--
|
|---|
| 7506 | > WRM-16.contacts.txt
|
|---|
| 7507 |
|
|---|
| 7508 |
|
|---|
| 7509 | Allowed overlap: -0.4
|
|---|
| 7510 | H-bond overlap reduction: 0.4
|
|---|
| 7511 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 7512 | Detect intra-residue contacts: False
|
|---|
| 7513 | Detect intra-molecule contacts: True
|
|---|
| 7514 |
|
|---|
| 7515 | 57 contacts
|
|---|
| 7516 | atom1 atom2 overlap distance
|
|---|
| 7517 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A ARG 144 HG2 0.382 2.498
|
|---|
| 7518 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A PRO 141 O 0.347 3.013
|
|---|
| 7519 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A ASP 301 HN 0.332 2.428
|
|---|
| 7520 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A PRO 313 HD1 0.278 2.602
|
|---|
| 7521 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A THR 300 HA 0.244 2.516
|
|---|
| 7522 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2GU8.pdbqt #1/A VAL 310 3HG2 0.217 2.663
|
|---|
| 7523 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A VAL 310 CG2 0.191 3.269
|
|---|
| 7524 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A PHE 145 HB2 0.173 2.707
|
|---|
| 7525 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A ARG 144 HE 0.160 1.900
|
|---|
| 7526 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A ARG 144 HE 0.104 2.506
|
|---|
| 7527 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A VAL 310 1HG2 0.094 2.666
|
|---|
| 7528 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A PRO 313 CD 0.077 3.503
|
|---|
| 7529 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2GU8.pdbqt #1/A ASP 301 HB2 0.074 2.806
|
|---|
| 7530 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A ASP 301 HN 0.042 2.718
|
|---|
| 7531 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A THR 299 HG1 0.035 1.985
|
|---|
| 7532 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A ARG 144 CG 0.002 3.578
|
|---|
| 7533 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A THR 299 O -0.001 3.241
|
|---|
| 7534 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A ASP 301 N -0.038 3.423
|
|---|
| 7535 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A THR 300 HA -0.045 2.655
|
|---|
| 7536 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A PHE 145 CB -0.051 3.631
|
|---|
| 7537 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A ARG 144 1HH2 -0.078 2.098
|
|---|
| 7538 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A PRO 141 HA -0.089 2.549
|
|---|
| 7539 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2GU8.pdbqt #1/A VAL 310 CG2 -0.106 3.686
|
|---|
| 7540 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2GU8.pdbqt #1/A ASP 301 CB -0.132 3.712
|
|---|
| 7541 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A THR 300 CA -0.133 3.593
|
|---|
| 7542 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A THR 300 3HG2 -0.136 2.896
|
|---|
| 7543 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A ARG 144 1HH2 -0.140 2.750
|
|---|
| 7544 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A ARG 144 NE -0.171 2.856
|
|---|
| 7545 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A VAL 310 3HG2 -0.210 2.970
|
|---|
| 7546 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A GLU 311 O -0.241 3.601
|
|---|
| 7547 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A PRO 313 CG -0.249 3.829
|
|---|
| 7548 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A PHE 145 CD1 -0.251 3.831
|
|---|
| 7549 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A ARG 144 CD -0.252 3.372
|
|---|
| 7550 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A PRO 141 C -0.252 3.832
|
|---|
| 7551 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A THR 299 O -0.253 3.493
|
|---|
| 7552 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A ARG 144 NE -0.260 3.495
|
|---|
| 7553 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A ASP 301 N -0.268 3.653
|
|---|
| 7554 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A THR 299 HB -0.289 3.169
|
|---|
| 7555 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A ARG 144 HG2 -0.290 3.170
|
|---|
| 7556 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A PHE 145 CG -0.293 3.873
|
|---|
| 7557 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A PRO 141 CA -0.296 3.456
|
|---|
| 7558 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A VAL 310 CG1 -0.301 3.461
|
|---|
| 7559 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A ARG 144 HE -0.306 3.186
|
|---|
| 7560 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A THR 300 CG2 -0.311 3.771
|
|---|
| 7561 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A THR 300 CA -0.313 3.433
|
|---|
| 7562 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A ASP 301 HB2 -0.319 3.079
|
|---|
| 7563 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A PHE 145 N -0.333 3.838
|
|---|
| 7564 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A PRO 141 CA -0.337 3.917
|
|---|
| 7565 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A PHE 145 CA -0.342 3.922
|
|---|
| 7566 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A ILE 305 1HD1 -0.361 3.121
|
|---|
| 7567 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A THR 299 C -0.363 3.483
|
|---|
| 7568 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A PRO 141 HB2 -0.372 2.982
|
|---|
| 7569 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A ARG 144 NH2 -0.373 3.018
|
|---|
| 7570 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A THR 299 OG1 -0.378 2.898
|
|---|
| 7571 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A THR 299 OG1 -0.384 3.494
|
|---|
| 7572 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A ARG 144 HG2 -0.393 2.813
|
|---|
| 7573 | 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 C 2GU8.pdbqt #1/A PRO 141 HA -0.395 3.275
|
|---|
| 7574 |
|
|---|
| 7575 |
|
|---|
| 7576 |
|
|---|
| 7577 | 57 contacts
|
|---|
| 7578 |
|
|---|
| 7579 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 7580 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2GU8--
|
|---|
| 7581 | > WRM-16.hbonds.txt
|
|---|
| 7582 |
|
|---|
| 7583 |
|
|---|
| 7584 | Finding intermodel H-bonds
|
|---|
| 7585 | Finding intramodel H-bonds
|
|---|
| 7586 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 7587 | Models used:
|
|---|
| 7588 | 1 2GU8.pdbqt
|
|---|
| 7589 | 2.1 2GU8--WRM-16.result.pdbqt
|
|---|
| 7590 |
|
|---|
| 7591 | 3 H-bonds
|
|---|
| 7592 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 7593 | 2GU8.pdbqt #1/A ARG 144 NE 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A ARG 144 HE 2.856 1.900
|
|---|
| 7594 | 2GU8.pdbqt #1/A ARG 144 NH2 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A ARG 144 1HH2 3.018 2.098
|
|---|
| 7595 | 2GU8.pdbqt #1/A THR 299 OG1 2GU8--WRM-16.result.pdbqt #2.1/? UNL 1 O 2GU8.pdbqt #1/A THR 299 HG1 2.898 1.985
|
|---|
| 7596 |
|
|---|
| 7597 |
|
|---|
| 7598 |
|
|---|
| 7599 | 3 hydrogen bonds found
|
|---|
| 7600 |
|
|---|
| 7601 | > select :UNL
|
|---|
| 7602 |
|
|---|
| 7603 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 7604 |
|
|---|
| 7605 | > label sel text "Ligand "
|
|---|
| 7606 |
|
|---|
| 7607 | > label height 1
|
|---|
| 7608 |
|
|---|
| 7609 | > ~select
|
|---|
| 7610 |
|
|---|
| 7611 | Nothing selected
|
|---|
| 7612 |
|
|---|
| 7613 | > 2dlabels text "Binding Energy: -8.1 kcal/mol" color red size 18 xpos .03
|
|---|
| 7614 | > ypos .95
|
|---|
| 7615 |
|
|---|
| 7616 | > 2dlabels text "2GU8 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 7617 |
|
|---|
| 7618 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2GU8--
|
|---|
| 7619 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 7620 | > true
|
|---|
| 7621 |
|
|---|
| 7622 | > select :UNL
|
|---|
| 7623 |
|
|---|
| 7624 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 7625 |
|
|---|
| 7626 | > view sel
|
|---|
| 7627 |
|
|---|
| 7628 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2GU8--
|
|---|
| 7629 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 7630 | > true
|
|---|
| 7631 |
|
|---|
| 7632 | > close
|
|---|
| 7633 |
|
|---|
| 7634 | > wait 5
|
|---|
| 7635 |
|
|---|
| 7636 | > set bgColor white
|
|---|
| 7637 |
|
|---|
| 7638 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/5VTB.pdbqt
|
|---|
| 7639 |
|
|---|
| 7640 | Chain information for 5VTB.pdbqt #1
|
|---|
| 7641 | ---
|
|---|
| 7642 | Chain | Description
|
|---|
| 7643 | A | No description available
|
|---|
| 7644 | B | No description available
|
|---|
| 7645 |
|
|---|
| 7646 | Opened 5VTB.pdbqt containing 1 structures (5433 atoms, 5510 bonds)
|
|---|
| 7647 |
|
|---|
| 7648 | > wait 5
|
|---|
| 7649 |
|
|---|
| 7650 | > hide surfaces
|
|---|
| 7651 |
|
|---|
| 7652 | > hide atoms
|
|---|
| 7653 |
|
|---|
| 7654 | > show cartoons
|
|---|
| 7655 |
|
|---|
| 7656 | > wait 5
|
|---|
| 7657 |
|
|---|
| 7658 | > addh
|
|---|
| 7659 |
|
|---|
| 7660 | Summary of feedback from adding hydrogens to 5VTB.pdbqt #1
|
|---|
| 7661 | ---
|
|---|
| 7662 | warnings | Not adding hydrogens to /A LYS 25 CB because it is missing heavy-
|
|---|
| 7663 | atom bond partners
|
|---|
| 7664 | Not adding hydrogens to /A LYS 26 CB because it is missing heavy-atom bond
|
|---|
| 7665 | partners
|
|---|
| 7666 | Not adding hydrogens to /A VAL 35 CB because it is missing heavy-atom bond
|
|---|
| 7667 | partners
|
|---|
| 7668 | Not adding hydrogens to /A ASP 52 CB because it is missing heavy-atom bond
|
|---|
| 7669 | partners
|
|---|
| 7670 | Not adding hydrogens to /A LYS 59 CB because it is missing heavy-atom bond
|
|---|
| 7671 | partners
|
|---|
| 7672 | 32 messages similar to the above omitted
|
|---|
| 7673 | notes | No usable SEQRES records for 5VTB.pdbqt (#1) chain A; guessing termini
|
|---|
| 7674 | instead
|
|---|
| 7675 | No usable SEQRES records for 5VTB.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 7676 | Chain-initial residues that are actual N termini: /A LYS 25, /B ARG 3
|
|---|
| 7677 | Chain-initial residues that are not actual N termini: /A LYS 59, /A GLY 113,
|
|---|
| 7678 | /A PRO 363
|
|---|
| 7679 | Chain-final residues that are actual C termini: /A ASP 411, /B GLU 16
|
|---|
| 7680 | Chain-final residues that are not actual C termini: /A THR 54, /A ASN 88, /A
|
|---|
| 7681 | GLU 352
|
|---|
| 7682 | 287 hydrogen bonds
|
|---|
| 7683 | Adding 'H' to /A LYS 59
|
|---|
| 7684 | Adding 'H' to /A GLY 113
|
|---|
| 7685 | /A THR 54 is not terminus, removing H atom from 'C'
|
|---|
| 7686 | /A ASN 88 is not terminus, removing H atom from 'C'
|
|---|
| 7687 | /A GLU 352 is not terminus, removing H atom from 'C'
|
|---|
| 7688 | -2 hydrogens added
|
|---|
| 7689 |
|
|---|
| 7690 |
|
|---|
| 7691 | > wait 5
|
|---|
| 7692 |
|
|---|
| 7693 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/5VTB--
|
|---|
| 7694 | > WRM-16.result.pdbqt
|
|---|
| 7695 |
|
|---|
| 7696 | Summary of feedback from opening
|
|---|
| 7697 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/5VTB--WRM-16.result.pdbqt
|
|---|
| 7698 | ---
|
|---|
| 7699 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 7700 | REMARK VINA RESULT: -8.4 0.000 0.000
|
|---|
| 7701 |
|
|---|
| 7702 | Ignored bad PDB record found on line 3
|
|---|
| 7703 | REMARK 5 active torsions:
|
|---|
| 7704 |
|
|---|
| 7705 | Ignored bad PDB record found on line 4
|
|---|
| 7706 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 7707 |
|
|---|
| 7708 | Ignored bad PDB record found on line 5
|
|---|
| 7709 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 7710 |
|
|---|
| 7711 | Ignored bad PDB record found on line 6
|
|---|
| 7712 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 7713 |
|
|---|
| 7714 | 184 messages similar to the above omitted
|
|---|
| 7715 |
|
|---|
| 7716 | Opened 5VTB--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 7717 | bonds)
|
|---|
| 7718 |
|
|---|
| 7719 | > wait 5
|
|---|
| 7720 |
|
|---|
| 7721 | > close #2.2-9
|
|---|
| 7722 |
|
|---|
| 7723 | > wait 5
|
|---|
| 7724 |
|
|---|
| 7725 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 7726 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5VTB--
|
|---|
| 7727 | > WRM-16.contacts.txt
|
|---|
| 7728 |
|
|---|
| 7729 |
|
|---|
| 7730 | Allowed overlap: -0.4
|
|---|
| 7731 | H-bond overlap reduction: 0.4
|
|---|
| 7732 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 7733 | Detect intra-residue contacts: False
|
|---|
| 7734 | Detect intra-molecule contacts: True
|
|---|
| 7735 |
|
|---|
| 7736 | 47 contacts
|
|---|
| 7737 | atom1 atom2 overlap distance
|
|---|
| 7738 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A GLN 324 2HE2 0.542 2.338
|
|---|
| 7739 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5VTB.pdbqt #1/A PRO 384 HB2 0.411 2.469
|
|---|
| 7740 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A GLN 324 NE2 0.359 3.146
|
|---|
| 7741 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5VTB.pdbqt #1/A TRP 382 O 0.261 3.099
|
|---|
| 7742 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A TRP 185 HN 0.260 2.500
|
|---|
| 7743 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5VTB.pdbqt #1/A PRO 384 CB 0.243 3.337
|
|---|
| 7744 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A PRO 327 HB2 0.217 2.543
|
|---|
| 7745 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5VTB.pdbqt #1/A PRO 327 HG1 0.111 2.769
|
|---|
| 7746 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A SER 184 HA 0.106 2.654
|
|---|
| 7747 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A PRO 327 HB2 0.056 2.554
|
|---|
| 7748 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 O 5VTB.pdbqt #1/A SER 234 HG -0.008 2.028
|
|---|
| 7749 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5VTB.pdbqt #1/A PRO 384 CA -0.067 3.647
|
|---|
| 7750 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 O 5VTB.pdbqt #1/A SER 280 HA -0.085 2.505
|
|---|
| 7751 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5VTB.pdbqt #1/A PRO 327 CG -0.089 3.669
|
|---|
| 7752 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 O 5VTB.pdbqt #1/A TRP 325 HB1 -0.103 2.523
|
|---|
| 7753 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A GLN 48 2HE2 -0.108 2.988
|
|---|
| 7754 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A TRP 185 N -0.114 3.499
|
|---|
| 7755 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A GLN 324 2HE2 -0.124 2.734
|
|---|
| 7756 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A SER 184 OG -0.150 3.410
|
|---|
| 7757 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A SER 234 HG -0.157 2.767
|
|---|
| 7758 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5VTB.pdbqt #1/A PRO 327 HB2 -0.165 3.045
|
|---|
| 7759 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5VTB.pdbqt #1/A PRO 327 CB -0.167 3.747
|
|---|
| 7760 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A TRP 382 HB2 -0.167 2.927
|
|---|
| 7761 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A SER 184 CA -0.177 3.637
|
|---|
| 7762 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A SER 184 HA -0.183 2.943
|
|---|
| 7763 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A PRO 327 CB -0.192 3.652
|
|---|
| 7764 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A PRO 327 CB -0.197 3.507
|
|---|
| 7765 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A LEU 183 O -0.205 3.565
|
|---|
| 7766 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5VTB.pdbqt #1/A PRO 384 N -0.232 3.737
|
|---|
| 7767 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 O 5VTB.pdbqt #1/A SER 234 OG -0.239 2.759
|
|---|
| 7768 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5VTB.pdbqt #1/A PRO 384 CD -0.256 3.836
|
|---|
| 7769 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A TRP 325 O -0.266 3.506
|
|---|
| 7770 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A GLN 48 1HE2 -0.291 3.051
|
|---|
| 7771 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A TRP 185 HN -0.309 3.069
|
|---|
| 7772 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 O 5VTB.pdbqt #1/A GLN 324 OE1 -0.311 3.251
|
|---|
| 7773 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A VAL 233 O -0.314 3.674
|
|---|
| 7774 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A GLN 324 CD -0.319 3.899
|
|---|
| 7775 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A SER 234 OG -0.319 3.429
|
|---|
| 7776 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 O 5VTB.pdbqt #1/A SER 234 OG -0.328 2.888
|
|---|
| 7777 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A GLN 48 NE2 -0.330 3.715
|
|---|
| 7778 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5VTB.pdbqt #1/A PRO 384 HA -0.334 3.214
|
|---|
| 7779 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 O 5VTB.pdbqt #1/A SER 234 CB -0.341 3.461
|
|---|
| 7780 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A GLN 324 NE2 -0.343 3.728
|
|---|
| 7781 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 O 5VTB.pdbqt #1/A SER 234 CB -0.350 3.510
|
|---|
| 7782 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 O 5VTB.pdbqt #1/A LEU 279 O -0.370 3.270
|
|---|
| 7783 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VTB.pdbqt #1/A GLN 48 1HE2 -0.379 3.139
|
|---|
| 7784 | 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 CL 5VTB.pdbqt #1/A PRO 384 CG -0.388 3.968
|
|---|
| 7785 |
|
|---|
| 7786 |
|
|---|
| 7787 |
|
|---|
| 7788 | 47 contacts
|
|---|
| 7789 |
|
|---|
| 7790 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 7791 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5VTB--
|
|---|
| 7792 | > WRM-16.hbonds.txt
|
|---|
| 7793 |
|
|---|
| 7794 |
|
|---|
| 7795 | Finding intermodel H-bonds
|
|---|
| 7796 | Finding intramodel H-bonds
|
|---|
| 7797 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 7798 | Models used:
|
|---|
| 7799 | 1 5VTB.pdbqt
|
|---|
| 7800 | 2.1 5VTB--WRM-16.result.pdbqt
|
|---|
| 7801 |
|
|---|
| 7802 | 1 H-bonds
|
|---|
| 7803 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 7804 | 5VTB.pdbqt #1/A SER 234 OG 5VTB--WRM-16.result.pdbqt #2.1/? UNL 1 O 5VTB.pdbqt #1/A SER 234 HG 2.759 2.028
|
|---|
| 7805 |
|
|---|
| 7806 |
|
|---|
| 7807 |
|
|---|
| 7808 | 1 hydrogen bonds found
|
|---|
| 7809 |
|
|---|
| 7810 | > select :UNL
|
|---|
| 7811 |
|
|---|
| 7812 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 7813 |
|
|---|
| 7814 | > label sel text "Ligand "
|
|---|
| 7815 |
|
|---|
| 7816 | > label height 1
|
|---|
| 7817 |
|
|---|
| 7818 | > ~select
|
|---|
| 7819 |
|
|---|
| 7820 | Nothing selected
|
|---|
| 7821 |
|
|---|
| 7822 | > 2dlabels text "Binding Energy: -8.4 kcal/mol" color red size 18 xpos .03
|
|---|
| 7823 | > ypos .95
|
|---|
| 7824 |
|
|---|
| 7825 | > 2dlabels text "5VTB WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 7826 |
|
|---|
| 7827 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5VTB--
|
|---|
| 7828 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 7829 | > true
|
|---|
| 7830 |
|
|---|
| 7831 | > select :UNL
|
|---|
| 7832 |
|
|---|
| 7833 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 7834 |
|
|---|
| 7835 | > view sel
|
|---|
| 7836 |
|
|---|
| 7837 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5VTB--
|
|---|
| 7838 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 7839 | > true
|
|---|
| 7840 |
|
|---|
| 7841 | > close
|
|---|
| 7842 |
|
|---|
| 7843 | > wait 5
|
|---|
| 7844 |
|
|---|
| 7845 | > set bgColor white
|
|---|
| 7846 |
|
|---|
| 7847 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/2D3J.pdbqt
|
|---|
| 7848 |
|
|---|
| 7849 | Chain information for 2D3J.pdbqt #1
|
|---|
| 7850 | ---
|
|---|
| 7851 | Chain | Description
|
|---|
| 7852 | A | No description available
|
|---|
| 7853 |
|
|---|
| 7854 | Opened 2D3J.pdbqt containing 1 structures (2441 atoms, 2470 bonds)
|
|---|
| 7855 |
|
|---|
| 7856 | > wait 5
|
|---|
| 7857 |
|
|---|
| 7858 | > hide surfaces
|
|---|
| 7859 |
|
|---|
| 7860 | > hide atoms
|
|---|
| 7861 |
|
|---|
| 7862 | > show cartoons
|
|---|
| 7863 |
|
|---|
| 7864 | > wait 5
|
|---|
| 7865 |
|
|---|
| 7866 | > addh
|
|---|
| 7867 |
|
|---|
| 7868 | Summary of feedback from adding hydrogens to 2D3J.pdbqt #1
|
|---|
| 7869 | ---
|
|---|
| 7870 | notes | No usable SEQRES records for 2D3J.pdbqt (#1) chain A; guessing termini
|
|---|
| 7871 | instead
|
|---|
| 7872 | Chain-initial residues that are actual N termini: /A GLY 1
|
|---|
| 7873 | Chain-initial residues that are not actual N termini:
|
|---|
| 7874 | Chain-final residues that are actual C termini: /A GLU 157
|
|---|
| 7875 | Chain-final residues that are not actual C termini:
|
|---|
| 7876 | 134 hydrogen bonds
|
|---|
| 7877 | 2 hydrogens added
|
|---|
| 7878 |
|
|---|
| 7879 |
|
|---|
| 7880 | > wait 5
|
|---|
| 7881 |
|
|---|
| 7882 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2D3J--
|
|---|
| 7883 | > WRM-16.result.pdbqt
|
|---|
| 7884 |
|
|---|
| 7885 | Summary of feedback from opening
|
|---|
| 7886 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2D3J--WRM-16.result.pdbqt
|
|---|
| 7887 | ---
|
|---|
| 7888 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 7889 | REMARK VINA RESULT: -6.9 0.000 0.000
|
|---|
| 7890 |
|
|---|
| 7891 | Ignored bad PDB record found on line 3
|
|---|
| 7892 | REMARK 5 active torsions:
|
|---|
| 7893 |
|
|---|
| 7894 | Ignored bad PDB record found on line 4
|
|---|
| 7895 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 7896 |
|
|---|
| 7897 | Ignored bad PDB record found on line 5
|
|---|
| 7898 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 7899 |
|
|---|
| 7900 | Ignored bad PDB record found on line 6
|
|---|
| 7901 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 7902 |
|
|---|
| 7903 | 184 messages similar to the above omitted
|
|---|
| 7904 |
|
|---|
| 7905 | Opened 2D3J--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 7906 | bonds)
|
|---|
| 7907 |
|
|---|
| 7908 | > wait 5
|
|---|
| 7909 |
|
|---|
| 7910 | > close #2.2-9
|
|---|
| 7911 |
|
|---|
| 7912 | > wait 5
|
|---|
| 7913 |
|
|---|
| 7914 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 7915 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2D3J--
|
|---|
| 7916 | > WRM-16.contacts.txt
|
|---|
| 7917 |
|
|---|
| 7918 |
|
|---|
| 7919 | Allowed overlap: -0.4
|
|---|
| 7920 | H-bond overlap reduction: 0.4
|
|---|
| 7921 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 7922 | Detect intra-residue contacts: False
|
|---|
| 7923 | Detect intra-molecule contacts: True
|
|---|
| 7924 |
|
|---|
| 7925 | 45 contacts
|
|---|
| 7926 | atom1 atom2 overlap distance
|
|---|
| 7927 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2D3J.pdbqt #1/A LEU 85 2HD1 0.384 2.496
|
|---|
| 7928 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ALA 55 HB3 0.246 2.514
|
|---|
| 7929 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 HZ 0.218 2.542
|
|---|
| 7930 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2D3J.pdbqt #1/A LEU 85 CD1 0.198 3.382
|
|---|
| 7931 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A VAL 123 3HG1 0.151 2.609
|
|---|
| 7932 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ALA 49 N 0.137 3.368
|
|---|
| 7933 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 CZ 0.129 3.451
|
|---|
| 7934 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ILE 148 3HD1 0.115 2.645
|
|---|
| 7935 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ILE 148 3HG2 0.068 2.692
|
|---|
| 7936 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ALA 49 HB3 0.051 2.829
|
|---|
| 7937 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ARG 47 HD3 -0.008 2.888
|
|---|
| 7938 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ALA 55 CB -0.044 3.504
|
|---|
| 7939 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ARG 47 HD3 -0.047 2.657
|
|---|
| 7940 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ARG 47 HD3 -0.064 2.824
|
|---|
| 7941 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ALA 49 CA -0.071 3.651
|
|---|
| 7942 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 CD2 -0.087 3.667
|
|---|
| 7943 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 HZ -0.097 2.977
|
|---|
| 7944 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ALA 49 CB -0.100 3.680
|
|---|
| 7945 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 CE2 -0.125 3.705
|
|---|
| 7946 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ARG 47 CD -0.137 3.717
|
|---|
| 7947 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 HZ -0.142 2.752
|
|---|
| 7948 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 CZ -0.164 3.624
|
|---|
| 7949 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ILE 148 CD1 -0.196 3.656
|
|---|
| 7950 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 CB -0.221 3.681
|
|---|
| 7951 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A VAL 123 CG1 -0.221 3.681
|
|---|
| 7952 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A VAL 123 3HG1 -0.232 2.992
|
|---|
| 7953 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 CG -0.235 3.695
|
|---|
| 7954 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PRO 54 HB2 -0.236 2.996
|
|---|
| 7955 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 CD2 -0.247 3.557
|
|---|
| 7956 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A LYS 48 C -0.250 3.830
|
|---|
| 7957 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ILE 148 3HG2 -0.280 3.040
|
|---|
| 7958 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ILE 148 CG2 -0.287 3.747
|
|---|
| 7959 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 HD2 -0.289 3.169
|
|---|
| 7960 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 CD1 -0.292 3.752
|
|---|
| 7961 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 CE1 -0.296 3.876
|
|---|
| 7962 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 O 2D3J.pdbqt #1/A ARG 47 NH1 -0.304 2.949
|
|---|
| 7963 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 HZ -0.325 3.085
|
|---|
| 7964 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 O 2D3J.pdbqt #1/A ARG 47 1HH1 -0.329 2.349
|
|---|
| 7965 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ARG 47 CD -0.348 3.658
|
|---|
| 7966 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 CG -0.349 3.659
|
|---|
| 7967 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 CB -0.352 3.812
|
|---|
| 7968 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 HE2 -0.357 3.237
|
|---|
| 7969 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ARG 47 CD -0.365 3.825
|
|---|
| 7970 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A ARG 47 O -0.370 3.730
|
|---|
| 7971 | 2D3J--WRM-16.result.pdbqt #2.1/? UNL 1 C 2D3J.pdbqt #1/A PHE 150 HB3 -0.374 3.134
|
|---|
| 7972 |
|
|---|
| 7973 |
|
|---|
| 7974 |
|
|---|
| 7975 | 45 contacts
|
|---|
| 7976 |
|
|---|
| 7977 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 7978 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2D3J--
|
|---|
| 7979 | > WRM-16.hbonds.txt
|
|---|
| 7980 |
|
|---|
| 7981 |
|
|---|
| 7982 | Finding intermodel H-bonds
|
|---|
| 7983 | Finding intramodel H-bonds
|
|---|
| 7984 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 7985 | Models used:
|
|---|
| 7986 | 1 2D3J.pdbqt
|
|---|
| 7987 | 2.1 2D3J--WRM-16.result.pdbqt
|
|---|
| 7988 |
|
|---|
| 7989 | 0 H-bonds
|
|---|
| 7990 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 7991 |
|
|---|
| 7992 |
|
|---|
| 7993 |
|
|---|
| 7994 | 0 hydrogen bonds found
|
|---|
| 7995 |
|
|---|
| 7996 | > select :UNL
|
|---|
| 7997 |
|
|---|
| 7998 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 7999 |
|
|---|
| 8000 | > label sel text "Ligand "
|
|---|
| 8001 |
|
|---|
| 8002 | > label height 1
|
|---|
| 8003 |
|
|---|
| 8004 | > ~select
|
|---|
| 8005 |
|
|---|
| 8006 | Nothing selected
|
|---|
| 8007 |
|
|---|
| 8008 | > 2dlabels text "Binding Energy: -6.9 kcal/mol" color red size 18 xpos .03
|
|---|
| 8009 | > ypos .95
|
|---|
| 8010 |
|
|---|
| 8011 | > 2dlabels text "2D3J WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 8012 |
|
|---|
| 8013 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2D3J--
|
|---|
| 8014 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 8015 | > true
|
|---|
| 8016 |
|
|---|
| 8017 | > select :UNL
|
|---|
| 8018 |
|
|---|
| 8019 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 8020 |
|
|---|
| 8021 | > view sel
|
|---|
| 8022 |
|
|---|
| 8023 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2D3J--
|
|---|
| 8024 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 8025 | > true
|
|---|
| 8026 |
|
|---|
| 8027 | > close
|
|---|
| 8028 |
|
|---|
| 8029 | > wait 5
|
|---|
| 8030 |
|
|---|
| 8031 | > set bgColor white
|
|---|
| 8032 |
|
|---|
| 8033 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/2E50.pdbqt
|
|---|
| 8034 |
|
|---|
| 8035 | Chain information for 2E50.pdbqt #1
|
|---|
| 8036 | ---
|
|---|
| 8037 | Chain | Description
|
|---|
| 8038 | A | No description available
|
|---|
| 8039 | B | No description available
|
|---|
| 8040 | P | No description available
|
|---|
| 8041 | Q | No description available
|
|---|
| 8042 |
|
|---|
| 8043 | Opened 2E50.pdbqt containing 1 structures (11470 atoms, 11602 bonds)
|
|---|
| 8044 |
|
|---|
| 8045 | > wait 5
|
|---|
| 8046 |
|
|---|
| 8047 | > hide surfaces
|
|---|
| 8048 |
|
|---|
| 8049 | > hide atoms
|
|---|
| 8050 |
|
|---|
| 8051 | > show cartoons
|
|---|
| 8052 |
|
|---|
| 8053 | > wait 5
|
|---|
| 8054 |
|
|---|
| 8055 | > addh
|
|---|
| 8056 |
|
|---|
| 8057 | Summary of feedback from adding hydrogens to 2E50.pdbqt #1
|
|---|
| 8058 | ---
|
|---|
| 8059 | warning | Not adding hydrogens to /B MET 145 CB because it is missing heavy-
|
|---|
| 8060 | atom bond partners
|
|---|
| 8061 | notes | No usable SEQRES records for 2E50.pdbqt (#1) chain A; guessing termini
|
|---|
| 8062 | instead
|
|---|
| 8063 | No usable SEQRES records for 2E50.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 8064 | No usable SEQRES records for 2E50.pdbqt (#1) chain P; guessing termini instead
|
|---|
| 8065 | No usable SEQRES records for 2E50.pdbqt (#1) chain Q; guessing termini instead
|
|---|
| 8066 | Chain-initial residues that are actual N termini: /A MET 1, /B SER 24, /P MET
|
|---|
| 8067 | 1, /Q SER 24
|
|---|
| 8068 | Chain-initial residues that are not actual N termini: /A ASP 21, /A SER 152,
|
|---|
| 8069 | /A PHE 189, /A ALA 201, /B SER 152, /B PHE 189, /B GLY 200, /P ALA 20, /P SER
|
|---|
| 8070 | 152, /P PHE 189, /P GLY 200, /Q SER 152, /Q PHE 189, /Q ALA 201
|
|---|
| 8071 | Chain-final residues that are actual C termini: /A VAL 222, /B PRO 223, /P VAL
|
|---|
| 8072 | 222, /Q PRO 223
|
|---|
| 8073 | Chain-final residues that are not actual C termini: /A SER 15, /A HIS 144, /A
|
|---|
| 8074 | MET 166, /A THR 194, /B MET 145, /B MET 166, /B THR 194, /P ASN 16, /P HIS
|
|---|
| 8075 | 144, /P THR 167, /P THR 194, /Q HIS 144, /Q TRP 160, /Q THR 194
|
|---|
| 8076 | 568 hydrogen bonds
|
|---|
| 8077 | Adding 'H' to /A ASP 21
|
|---|
| 8078 | Adding 'H' to /A SER 152
|
|---|
| 8079 | Adding 'H' to /A PHE 189
|
|---|
| 8080 | Adding 'H' to /A ALA 201
|
|---|
| 8081 | Adding 'H' to /B SER 152
|
|---|
| 8082 | 9 messages similar to the above omitted
|
|---|
| 8083 | /A SER 15 is not terminus, removing H atom from 'C'
|
|---|
| 8084 | /A HIS 144 is not terminus, removing H atom from 'C'
|
|---|
| 8085 | /A MET 166 is not terminus, removing H atom from 'C'
|
|---|
| 8086 | /A THR 194 is not terminus, removing H atom from 'C'
|
|---|
| 8087 | /B MET 145 is not terminus, removing H atom from 'C'
|
|---|
| 8088 | 9 messages similar to the above omitted
|
|---|
| 8089 | -41 hydrogens added
|
|---|
| 8090 |
|
|---|
| 8091 |
|
|---|
| 8092 | > wait 5
|
|---|
| 8093 |
|
|---|
| 8094 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2E50--
|
|---|
| 8095 | > WRM-16.result.pdbqt
|
|---|
| 8096 |
|
|---|
| 8097 | Summary of feedback from opening
|
|---|
| 8098 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2E50--WRM-16.result.pdbqt
|
|---|
| 8099 | ---
|
|---|
| 8100 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 8101 | REMARK VINA RESULT: -8.8 0.000 0.000
|
|---|
| 8102 |
|
|---|
| 8103 | Ignored bad PDB record found on line 3
|
|---|
| 8104 | REMARK 5 active torsions:
|
|---|
| 8105 |
|
|---|
| 8106 | Ignored bad PDB record found on line 4
|
|---|
| 8107 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 8108 |
|
|---|
| 8109 | Ignored bad PDB record found on line 5
|
|---|
| 8110 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 8111 |
|
|---|
| 8112 | Ignored bad PDB record found on line 6
|
|---|
| 8113 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 8114 |
|
|---|
| 8115 | 184 messages similar to the above omitted
|
|---|
| 8116 |
|
|---|
| 8117 | Opened 2E50--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 8118 | bonds)
|
|---|
| 8119 |
|
|---|
| 8120 | > wait 5
|
|---|
| 8121 |
|
|---|
| 8122 | > close #2.2-9
|
|---|
| 8123 |
|
|---|
| 8124 | > wait 5
|
|---|
| 8125 |
|
|---|
| 8126 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 8127 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2E50--
|
|---|
| 8128 | > WRM-16.contacts.txt
|
|---|
| 8129 |
|
|---|
| 8130 |
|
|---|
| 8131 | Allowed overlap: -0.4
|
|---|
| 8132 | H-bond overlap reduction: 0.4
|
|---|
| 8133 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 8134 | Detect intra-residue contacts: False
|
|---|
| 8135 | Detect intra-molecule contacts: True
|
|---|
| 8136 |
|
|---|
| 8137 | 49 contacts
|
|---|
| 8138 | atom1 atom2 overlap distance
|
|---|
| 8139 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A GLU 116 HB2 0.217 2.543
|
|---|
| 8140 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2E50.pdbqt #1/A PRO 214 HG1 0.160 2.720
|
|---|
| 8141 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A GLU 114 HN 0.145 2.735
|
|---|
| 8142 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 O 2E50.pdbqt #1/A GLN 65 HB2 0.121 2.339
|
|---|
| 8143 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A GLU 114 HB1 0.092 2.668
|
|---|
| 8144 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A TRP 213 HD1 0.078 2.682
|
|---|
| 8145 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ASN 61 O 0.052 3.308
|
|---|
| 8146 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A TRP 213 CD1 -0.046 3.506
|
|---|
| 8147 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2E50.pdbqt #1/A PRO 214 CG -0.080 3.660
|
|---|
| 8148 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ASP 117 HN -0.136 2.896
|
|---|
| 8149 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ASN 61 HB1 -0.144 3.024
|
|---|
| 8150 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 O 2E50.pdbqt #1/A GLN 65 CB -0.152 3.312
|
|---|
| 8151 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A GLU 116 N -0.156 3.541
|
|---|
| 8152 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A GLU 116 CB -0.162 3.622
|
|---|
| 8153 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A GLU 116 HB2 -0.168 2.928
|
|---|
| 8154 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A PHE 68 CE1 -0.182 3.642
|
|---|
| 8155 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ASN 61 CB -0.188 3.768
|
|---|
| 8156 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A GLU 114 N -0.196 3.701
|
|---|
| 8157 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ASN 61 HB1 -0.198 2.808
|
|---|
| 8158 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A TRP 213 HE1 -0.224 2.984
|
|---|
| 8159 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ASN 61 HB1 -0.225 2.835
|
|---|
| 8160 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A GLU 114 HB1 -0.236 3.116
|
|---|
| 8161 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A PHE 68 CZ -0.245 3.705
|
|---|
| 8162 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A GLU 114 CB -0.258 3.718
|
|---|
| 8163 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A PHE 68 CZ -0.261 3.721
|
|---|
| 8164 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ARG 64 NE -0.263 3.648
|
|---|
| 8165 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ARG 64 CZ -0.277 3.737
|
|---|
| 8166 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A PHE 68 CE2 -0.278 3.738
|
|---|
| 8167 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ARG 64 NH1 -0.279 3.664
|
|---|
| 8168 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 O 2E50.pdbqt #1/A ASN 61 O -0.292 3.232
|
|---|
| 8169 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ARG 64 HD2 -0.294 3.054
|
|---|
| 8170 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A GLU 116 HN -0.296 3.056
|
|---|
| 8171 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A GLU 114 O -0.298 3.538
|
|---|
| 8172 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ARG 64 HD2 -0.303 3.063
|
|---|
| 8173 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ASN 61 OD1 -0.315 3.405
|
|---|
| 8174 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A GLU 116 N -0.318 3.703
|
|---|
| 8175 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A GLU 114 CB -0.319 3.899
|
|---|
| 8176 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ARG 64 CD -0.323 3.783
|
|---|
| 8177 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2E50.pdbqt #1/A PRO 214 CB -0.323 3.903
|
|---|
| 8178 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ASN 61 ND2 -0.330 3.835
|
|---|
| 8179 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ASN 61 OD1 -0.332 3.422
|
|---|
| 8180 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A PHE 68 CE2 -0.337 3.797
|
|---|
| 8181 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A PHE 68 CZ -0.340 3.650
|
|---|
| 8182 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A ASN 61 CA -0.362 3.942
|
|---|
| 8183 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A TRP 213 NE1 -0.364 3.749
|
|---|
| 8184 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A PHE 68 CZ -0.365 3.825
|
|---|
| 8185 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A PHE 68 CZ -0.379 3.839
|
|---|
| 8186 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A GLU 116 CB -0.383 3.843
|
|---|
| 8187 | 2E50--WRM-16.result.pdbqt #2.1/? UNL 1 C 2E50.pdbqt #1/A TRP 213 NE1 -0.385 3.770
|
|---|
| 8188 |
|
|---|
| 8189 |
|
|---|
| 8190 |
|
|---|
| 8191 | 49 contacts
|
|---|
| 8192 |
|
|---|
| 8193 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 8194 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2E50--
|
|---|
| 8195 | > WRM-16.hbonds.txt
|
|---|
| 8196 |
|
|---|
| 8197 |
|
|---|
| 8198 | Finding intermodel H-bonds
|
|---|
| 8199 | Finding intramodel H-bonds
|
|---|
| 8200 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 8201 | Models used:
|
|---|
| 8202 | 1 2E50.pdbqt
|
|---|
| 8203 | 2.1 2E50--WRM-16.result.pdbqt
|
|---|
| 8204 |
|
|---|
| 8205 | 0 H-bonds
|
|---|
| 8206 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 8207 |
|
|---|
| 8208 |
|
|---|
| 8209 |
|
|---|
| 8210 | 0 hydrogen bonds found
|
|---|
| 8211 |
|
|---|
| 8212 | > select :UNL
|
|---|
| 8213 |
|
|---|
| 8214 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 8215 |
|
|---|
| 8216 | > label sel text "Ligand "
|
|---|
| 8217 |
|
|---|
| 8218 | > label height 1
|
|---|
| 8219 |
|
|---|
| 8220 | > ~select
|
|---|
| 8221 |
|
|---|
| 8222 | Nothing selected
|
|---|
| 8223 |
|
|---|
| 8224 | > 2dlabels text "Binding Energy: -8.8 kcal/mol" color red size 18 xpos .03
|
|---|
| 8225 | > ypos .95
|
|---|
| 8226 |
|
|---|
| 8227 | > 2dlabels text "2E50 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 8228 |
|
|---|
| 8229 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2E50--
|
|---|
| 8230 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 8231 | > true
|
|---|
| 8232 |
|
|---|
| 8233 | > select :UNL
|
|---|
| 8234 |
|
|---|
| 8235 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 8236 |
|
|---|
| 8237 | > view sel
|
|---|
| 8238 |
|
|---|
| 8239 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2E50--
|
|---|
| 8240 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 8241 | > true
|
|---|
| 8242 |
|
|---|
| 8243 | > close
|
|---|
| 8244 |
|
|---|
| 8245 | > wait 5
|
|---|
| 8246 |
|
|---|
| 8247 | > set bgColor white
|
|---|
| 8248 |
|
|---|
| 8249 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/5VBN.pdbqt
|
|---|
| 8250 |
|
|---|
| 8251 | Chain information for 5VBN.pdbqt #1
|
|---|
| 8252 | ---
|
|---|
| 8253 | Chain | Description
|
|---|
| 8254 | A E | No description available
|
|---|
| 8255 | B F | No description available
|
|---|
| 8256 |
|
|---|
| 8257 | Opened 5VBN.pdbqt containing 1 structures (17529 atoms, 17769 bonds)
|
|---|
| 8258 |
|
|---|
| 8259 | > wait 5
|
|---|
| 8260 |
|
|---|
| 8261 | > hide surfaces
|
|---|
| 8262 |
|
|---|
| 8263 | > hide atoms
|
|---|
| 8264 |
|
|---|
| 8265 | > show cartoons
|
|---|
| 8266 |
|
|---|
| 8267 | > wait 5
|
|---|
| 8268 |
|
|---|
| 8269 | > addh
|
|---|
| 8270 |
|
|---|
| 8271 | Summary of feedback from adding hydrogens to 5VBN.pdbqt #1
|
|---|
| 8272 | ---
|
|---|
| 8273 | notes | No usable SEQRES records for 5VBN.pdbqt (#1) chain A; guessing termini
|
|---|
| 8274 | instead
|
|---|
| 8275 | No usable SEQRES records for 5VBN.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 8276 | No usable SEQRES records for 5VBN.pdbqt (#1) chain E; guessing termini instead
|
|---|
| 8277 | No usable SEQRES records for 5VBN.pdbqt (#1) chain F; guessing termini instead
|
|---|
| 8278 | Chain-initial residues that are actual N termini: /A HIS 84, /B SER 2150, /E
|
|---|
| 8279 | HIS 84, /F SER 2150
|
|---|
| 8280 | Chain-initial residues that are not actual N termini: /A PHE 163, /B PRO 2183,
|
|---|
| 8281 | /E PHE 163, /F PRO 2183
|
|---|
| 8282 | Chain-final residues that are actual C termini: /A PHE 527, /B PRO 2282, /E
|
|---|
| 8283 | PHE 527, /F PRO 2282
|
|---|
| 8284 | Chain-final residues that are not actual C termini: /A GLU 145, /B SER 2174,
|
|---|
| 8285 | /E GLU 145, /F SER 2174
|
|---|
| 8286 | 854 hydrogen bonds
|
|---|
| 8287 | Adding 'H' to /A PHE 163
|
|---|
| 8288 | Adding 'H' to /E PHE 163
|
|---|
| 8289 | /A GLU 145 is not terminus, removing H atom from 'C'
|
|---|
| 8290 | /B SER 2174 is not terminus, removing H atom from 'C'
|
|---|
| 8291 | /E GLU 145 is not terminus, removing H atom from 'C'
|
|---|
| 8292 | /F SER 2174 is not terminus, removing H atom from 'C'
|
|---|
| 8293 | 35 hydrogens added
|
|---|
| 8294 |
|
|---|
| 8295 |
|
|---|
| 8296 | > wait 5
|
|---|
| 8297 |
|
|---|
| 8298 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/5VBN--
|
|---|
| 8299 | > WRM-16.result.pdbqt
|
|---|
| 8300 |
|
|---|
| 8301 | Summary of feedback from opening
|
|---|
| 8302 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/5VBN--WRM-16.result.pdbqt
|
|---|
| 8303 | ---
|
|---|
| 8304 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 8305 | REMARK VINA RESULT: -8.3 0.000 0.000
|
|---|
| 8306 |
|
|---|
| 8307 | Ignored bad PDB record found on line 3
|
|---|
| 8308 | REMARK 5 active torsions:
|
|---|
| 8309 |
|
|---|
| 8310 | Ignored bad PDB record found on line 4
|
|---|
| 8311 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 8312 |
|
|---|
| 8313 | Ignored bad PDB record found on line 5
|
|---|
| 8314 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 8315 |
|
|---|
| 8316 | Ignored bad PDB record found on line 6
|
|---|
| 8317 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 8318 |
|
|---|
| 8319 | 184 messages similar to the above omitted
|
|---|
| 8320 |
|
|---|
| 8321 | Opened 5VBN--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 8322 | bonds)
|
|---|
| 8323 |
|
|---|
| 8324 | > wait 5
|
|---|
| 8325 |
|
|---|
| 8326 | > close #2.2-9
|
|---|
| 8327 |
|
|---|
| 8328 | > wait 5
|
|---|
| 8329 |
|
|---|
| 8330 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 8331 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5VBN--
|
|---|
| 8332 | > WRM-16.contacts.txt
|
|---|
| 8333 |
|
|---|
| 8334 |
|
|---|
| 8335 | Allowed overlap: -0.4
|
|---|
| 8336 | H-bond overlap reduction: 0.4
|
|---|
| 8337 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 8338 | Detect intra-residue contacts: False
|
|---|
| 8339 | Detect intra-molecule contacts: True
|
|---|
| 8340 |
|
|---|
| 8341 | 63 contacts
|
|---|
| 8342 | atom1 atom2 overlap distance
|
|---|
| 8343 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A LEU 190 1HD2 0.442 2.438
|
|---|
| 8344 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/B LEU 2216 HB2 0.235 2.525
|
|---|
| 8345 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A LEU 190 CD2 0.213 3.367
|
|---|
| 8346 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A GLN 189 O 0.052 3.308
|
|---|
| 8347 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PRO 455 HG2 0.023 2.737
|
|---|
| 8348 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A TYR 457 HB2 0.015 2.595
|
|---|
| 8349 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PRO 455 HB1 -0.011 2.621
|
|---|
| 8350 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/B SER 2231 HG -0.027 2.787
|
|---|
| 8351 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A THR 188 3HG2 -0.054 2.814
|
|---|
| 8352 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PRO 455 HB1 -0.055 2.815
|
|---|
| 8353 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A TYR 457 HB2 -0.081 2.841
|
|---|
| 8354 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PRO 455 HA -0.095 2.855
|
|---|
| 8355 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PRO 455 CB -0.121 3.581
|
|---|
| 8356 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A TYR 457 HB2 -0.126 2.886
|
|---|
| 8357 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PHE 130 CZ -0.136 3.596
|
|---|
| 8358 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A ALA 221 HB1 -0.136 2.896
|
|---|
| 8359 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A TYR 457 HB2 -0.139 3.019
|
|---|
| 8360 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A ALA 221 HB1 -0.152 2.912
|
|---|
| 8361 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A TYR 457 CB -0.156 3.616
|
|---|
| 8362 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A MET 186 CE -0.163 3.623
|
|---|
| 8363 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A TYR 457 HD1 -0.168 3.048
|
|---|
| 8364 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/B LEU 2216 CB -0.173 3.633
|
|---|
| 8365 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/B SER 2231 OG -0.175 3.555
|
|---|
| 8366 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PRO 455 HA -0.177 2.937
|
|---|
| 8367 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A GLN 189 C -0.183 3.763
|
|---|
| 8368 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PRO 455 CA -0.202 3.662
|
|---|
| 8369 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A TYR 457 CB -0.204 3.664
|
|---|
| 8370 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PRO 455 CG -0.206 3.666
|
|---|
| 8371 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PRO 455 HB1 -0.216 2.826
|
|---|
| 8372 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A ALA 221 CB -0.222 3.682
|
|---|
| 8373 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/B SER 2231 OG -0.228 3.488
|
|---|
| 8374 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A LEU 190 HA -0.229 3.109
|
|---|
| 8375 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A LEU 456 3HD1 -0.231 3.111
|
|---|
| 8376 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PHE 130 CE2 -0.231 3.691
|
|---|
| 8377 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A MET 186 HE2 -0.236 2.996
|
|---|
| 8378 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 O 5VBN.pdbqt #1/A GLU 220 OE2 -0.242 3.182
|
|---|
| 8379 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/B SER 2231 HG -0.247 3.007
|
|---|
| 8380 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/B LEU 2216 3HD1 -0.254 3.014
|
|---|
| 8381 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A THR 188 HB -0.257 3.137
|
|---|
| 8382 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PHE 130 CE2 -0.260 3.720
|
|---|
| 8383 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PRO 455 CB -0.262 3.722
|
|---|
| 8384 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A TYR 457 CB -0.265 3.725
|
|---|
| 8385 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A TYR 457 CB -0.268 3.578
|
|---|
| 8386 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 O 5VBN.pdbqt #1/B LEU 2216 O -0.275 3.175
|
|---|
| 8387 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A LYS 126 HE2 -0.301 3.181
|
|---|
| 8388 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A TYR 457 HB1 -0.303 3.063
|
|---|
| 8389 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PRO 455 CA -0.313 3.773
|
|---|
| 8390 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A TYR 457 CB -0.313 3.773
|
|---|
| 8391 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A ALA 221 CB -0.323 3.783
|
|---|
| 8392 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A MET 186 HE2 -0.328 3.088
|
|---|
| 8393 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A THR 188 CG2 -0.330 3.790
|
|---|
| 8394 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A GLU 220 OE2 -0.346 3.586
|
|---|
| 8395 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/B LEU 2216 O -0.348 3.588
|
|---|
| 8396 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PRO 455 CB -0.353 3.663
|
|---|
| 8397 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PRO 455 HG2 -0.363 3.123
|
|---|
| 8398 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A TYR 457 HE1 -0.366 2.976
|
|---|
| 8399 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PRO 455 HG2 -0.374 3.134
|
|---|
| 8400 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A LYS 126 CE -0.382 3.962
|
|---|
| 8401 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A TYR 457 CG -0.383 3.843
|
|---|
| 8402 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A TYR 457 HB1 -0.385 2.995
|
|---|
| 8403 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A PRO 455 CG -0.387 3.847
|
|---|
| 8404 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/A TYR 457 CD1 -0.395 3.975
|
|---|
| 8405 | 5VBN--WRM-16.result.pdbqt #2.1/? UNL 1 C 5VBN.pdbqt #1/B LEU 2216 HB2 -0.398 3.158
|
|---|
| 8406 |
|
|---|
| 8407 |
|
|---|
| 8408 |
|
|---|
| 8409 | 63 contacts
|
|---|
| 8410 |
|
|---|
| 8411 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 8412 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5VBN--
|
|---|
| 8413 | > WRM-16.hbonds.txt
|
|---|
| 8414 |
|
|---|
| 8415 |
|
|---|
| 8416 | Finding intermodel H-bonds
|
|---|
| 8417 | Finding intramodel H-bonds
|
|---|
| 8418 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 8419 | Models used:
|
|---|
| 8420 | 1 5VBN.pdbqt
|
|---|
| 8421 | 2.1 5VBN--WRM-16.result.pdbqt
|
|---|
| 8422 |
|
|---|
| 8423 | 0 H-bonds
|
|---|
| 8424 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 8425 |
|
|---|
| 8426 |
|
|---|
| 8427 |
|
|---|
| 8428 | 0 hydrogen bonds found
|
|---|
| 8429 |
|
|---|
| 8430 | > select :UNL
|
|---|
| 8431 |
|
|---|
| 8432 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 8433 |
|
|---|
| 8434 | > label sel text "Ligand "
|
|---|
| 8435 |
|
|---|
| 8436 | > label height 1
|
|---|
| 8437 |
|
|---|
| 8438 | > ~select
|
|---|
| 8439 |
|
|---|
| 8440 | Nothing selected
|
|---|
| 8441 |
|
|---|
| 8442 | > 2dlabels text "Binding Energy: -8.3 kcal/mol" color red size 18 xpos .03
|
|---|
| 8443 | > ypos .95
|
|---|
| 8444 |
|
|---|
| 8445 | > 2dlabels text "5VBN WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 8446 |
|
|---|
| 8447 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5VBN--
|
|---|
| 8448 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 8449 | > true
|
|---|
| 8450 |
|
|---|
| 8451 | > select :UNL
|
|---|
| 8452 |
|
|---|
| 8453 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 8454 |
|
|---|
| 8455 | > view sel
|
|---|
| 8456 |
|
|---|
| 8457 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/5VBN--
|
|---|
| 8458 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 8459 | > true
|
|---|
| 8460 |
|
|---|
| 8461 | > close
|
|---|
| 8462 |
|
|---|
| 8463 | > wait 5
|
|---|
| 8464 |
|
|---|
| 8465 | > set bgColor white
|
|---|
| 8466 |
|
|---|
| 8467 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/3ALN.pdbqt
|
|---|
| 8468 |
|
|---|
| 8469 | Chain information for 3ALN.pdbqt #1
|
|---|
| 8470 | ---
|
|---|
| 8471 | Chain | Description
|
|---|
| 8472 | A | No description available
|
|---|
| 8473 | B | No description available
|
|---|
| 8474 | C | No description available
|
|---|
| 8475 |
|
|---|
| 8476 | Opened 3ALN.pdbqt containing 1 structures (11428 atoms, 11539 bonds)
|
|---|
| 8477 |
|
|---|
| 8478 | > wait 5
|
|---|
| 8479 |
|
|---|
| 8480 | > hide surfaces
|
|---|
| 8481 |
|
|---|
| 8482 | > hide atoms
|
|---|
| 8483 |
|
|---|
| 8484 | > show cartoons
|
|---|
| 8485 |
|
|---|
| 8486 | > wait 5
|
|---|
| 8487 |
|
|---|
| 8488 | > addh
|
|---|
| 8489 |
|
|---|
| 8490 | Summary of feedback from adding hydrogens to 3ALN.pdbqt #1
|
|---|
| 8491 | ---
|
|---|
| 8492 | warnings | Not adding hydrogens to /A SER 83 CB because it is missing heavy-
|
|---|
| 8493 | atom bond partners
|
|---|
| 8494 | Not adding hydrogens to /A LYS 86 CB because it is missing heavy-atom bond
|
|---|
| 8495 | partners
|
|---|
| 8496 | Not adding hydrogens to /A LYS 88 CB because it is missing heavy-atom bond
|
|---|
| 8497 | partners
|
|---|
| 8498 | Not adding hydrogens to /A LEU 105 C because it is missing heavy-atom bond
|
|---|
| 8499 | partners
|
|---|
| 8500 | Not adding hydrogens to /A ASP 138 CB because it is missing heavy-atom bond
|
|---|
| 8501 | partners
|
|---|
| 8502 | 30 messages similar to the above omitted
|
|---|
| 8503 | The following atoms were skipped as donors/acceptors due to missing heavy-atom
|
|---|
| 8504 | bond partners: /A PRO 308 N
|
|---|
| 8505 | notes | No usable SEQRES records for 3ALN.pdbqt (#1) chain A; guessing termini
|
|---|
| 8506 | instead
|
|---|
| 8507 | No usable SEQRES records for 3ALN.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 8508 | No usable SEQRES records for 3ALN.pdbqt (#1) chain C; guessing termini instead
|
|---|
| 8509 | Chain-initial residues that are actual N termini: /A SER 83, /B SER 84, /C GLU
|
|---|
| 8510 | 100
|
|---|
| 8511 | Chain-initial residues that are not actual N termini: /A TYR 284, /A THR 318,
|
|---|
| 8512 | /B TYR 284, /B ASP 324, /C ASN 117, /C ILE 127, /C CYS 158, /C CYS 174, /C LYS
|
|---|
| 8513 | 231, /C SER 288, /C PRO 325
|
|---|
| 8514 | Chain-final residues that are actual C termini: /A PRO 389, /B ALA 390, /C ALA
|
|---|
| 8515 | 390
|
|---|
| 8516 | Chain-final residues that are not actual C termini: /A GLN 253, /A TRP 310, /B
|
|---|
| 8517 | LEU 254, /B PRO 308, /C GLU 107, /C VAL 120, /C THR 136, /C TYR 165, /C LYS
|
|---|
| 8518 | 224, /C PHE 248, /C PHE 305
|
|---|
| 8519 | 465 hydrogen bonds
|
|---|
| 8520 | Adding 'H' to /A TYR 284
|
|---|
| 8521 | Adding 'H' to /A THR 318
|
|---|
| 8522 | Adding 'H' to /B TYR 284
|
|---|
| 8523 | Adding 'H' to /B ASP 324
|
|---|
| 8524 | Adding 'H' to /C ASN 117
|
|---|
| 8525 | 5 messages similar to the above omitted
|
|---|
| 8526 | /A GLN 253 is not terminus, removing H atom from 'C'
|
|---|
| 8527 | /A TRP 310 is not terminus, removing H atom from 'C'
|
|---|
| 8528 | /B LEU 254 is not terminus, removing H atom from 'C'
|
|---|
| 8529 | /B PRO 308 is not terminus, removing H atom from 'C'
|
|---|
| 8530 | /C GLU 107 is not terminus, removing H atom from 'C'
|
|---|
| 8531 | 6 messages similar to the above omitted
|
|---|
| 8532 | -6 hydrogens added
|
|---|
| 8533 |
|
|---|
| 8534 |
|
|---|
| 8535 | > wait 5
|
|---|
| 8536 |
|
|---|
| 8537 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/3ALN--
|
|---|
| 8538 | > WRM-16.result.pdbqt
|
|---|
| 8539 |
|
|---|
| 8540 | Summary of feedback from opening
|
|---|
| 8541 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/3ALN--WRM-16.result.pdbqt
|
|---|
| 8542 | ---
|
|---|
| 8543 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 8544 | REMARK VINA RESULT: -8.7 0.000 0.000
|
|---|
| 8545 |
|
|---|
| 8546 | Ignored bad PDB record found on line 3
|
|---|
| 8547 | REMARK 5 active torsions:
|
|---|
| 8548 |
|
|---|
| 8549 | Ignored bad PDB record found on line 4
|
|---|
| 8550 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 8551 |
|
|---|
| 8552 | Ignored bad PDB record found on line 5
|
|---|
| 8553 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 8554 |
|
|---|
| 8555 | Ignored bad PDB record found on line 6
|
|---|
| 8556 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 8557 |
|
|---|
| 8558 | 184 messages similar to the above omitted
|
|---|
| 8559 |
|
|---|
| 8560 | Opened 3ALN--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 8561 | bonds)
|
|---|
| 8562 |
|
|---|
| 8563 | > wait 5
|
|---|
| 8564 |
|
|---|
| 8565 | > close #2.2-9
|
|---|
| 8566 |
|
|---|
| 8567 | > wait 5
|
|---|
| 8568 |
|
|---|
| 8569 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 8570 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3ALN--
|
|---|
| 8571 | > WRM-16.contacts.txt
|
|---|
| 8572 |
|
|---|
| 8573 |
|
|---|
| 8574 | Allowed overlap: -0.4
|
|---|
| 8575 | H-bond overlap reduction: 0.4
|
|---|
| 8576 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 8577 | Detect intra-residue contacts: False
|
|---|
| 8578 | Detect intra-molecule contacts: True
|
|---|
| 8579 |
|
|---|
| 8580 | 50 contacts
|
|---|
| 8581 | atom1 atom2 overlap distance
|
|---|
| 8582 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3ALN.pdbqt #1/A TYR 113 HN 0.426 2.454
|
|---|
| 8583 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A GLY 111 HA1 0.385 2.375
|
|---|
| 8584 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A LYS 131 HE1 0.145 2.615
|
|---|
| 8585 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A THR 183 HA 0.134 2.626
|
|---|
| 8586 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A GLY 111 HA1 0.097 2.513
|
|---|
| 8587 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3ALN.pdbqt #1/A TYR 113 N 0.090 3.415
|
|---|
| 8588 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A VAL 116 3HG2 0.087 2.523
|
|---|
| 8589 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A LYS 187 HE1 0.085 2.795
|
|---|
| 8590 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3ALN.pdbqt #1/A LYS 131 HZ1 0.045 2.835
|
|---|
| 8591 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A ILE 108 1HG2 0.033 2.727
|
|---|
| 8592 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A GLY 111 HA1 0.027 2.733
|
|---|
| 8593 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A MET 181 O -0.005 3.245
|
|---|
| 8594 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A GLY 111 CA -0.019 3.479
|
|---|
| 8595 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A LEU 236 3HD1 -0.024 2.904
|
|---|
| 8596 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A LYS 131 CE -0.041 3.501
|
|---|
| 8597 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A MET 178 SD -0.068 3.730
|
|---|
| 8598 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A LEU 236 CD1 -0.070 3.650
|
|---|
| 8599 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 O 3ALN.pdbqt #1/A VAL 116 3HG2 -0.075 2.495
|
|---|
| 8600 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A SER 233 HG -0.104 2.864
|
|---|
| 8601 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A ILE 108 1HG2 -0.125 2.885
|
|---|
| 8602 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3ALN.pdbqt #1/A ALA 112 N -0.153 3.658
|
|---|
| 8603 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A LYS 187 CE -0.159 3.739
|
|---|
| 8604 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A LYS 131 NZ -0.161 3.546
|
|---|
| 8605 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A ILE 108 CG2 -0.166 3.626
|
|---|
| 8606 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3ALN.pdbqt #1/A LYS 131 NZ -0.194 3.699
|
|---|
| 8607 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A GLY 111 HA1 -0.208 2.968
|
|---|
| 8608 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A THR 183 CA -0.221 3.681
|
|---|
| 8609 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 O 3ALN.pdbqt #1/A ALA 129 CB -0.224 3.384
|
|---|
| 8610 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A ILE 108 1HG2 -0.224 2.984
|
|---|
| 8611 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A ILE 108 CG2 -0.237 3.697
|
|---|
| 8612 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 O 3ALN.pdbqt #1/A ALA 129 HB2 -0.237 2.697
|
|---|
| 8613 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A GLY 111 CA -0.248 3.558
|
|---|
| 8614 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A GLY 111 CA -0.257 3.717
|
|---|
| 8615 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A THR 183 HA -0.278 3.038
|
|---|
| 8616 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 O 3ALN.pdbqt #1/A SER 233 OG -0.287 2.807
|
|---|
| 8617 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A VAL 116 CG2 -0.305 3.615
|
|---|
| 8618 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A SER 233 OG -0.305 3.565
|
|---|
| 8619 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3ALN.pdbqt #1/A GLY 114 N -0.308 3.813
|
|---|
| 8620 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A ALA 112 HN -0.324 3.084
|
|---|
| 8621 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 O 3ALN.pdbqt #1/A VAL 116 CG2 -0.327 3.447
|
|---|
| 8622 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A ALA 129 CB -0.329 3.909
|
|---|
| 8623 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A ILE 108 3HD1 -0.337 3.097
|
|---|
| 8624 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 CL 3ALN.pdbqt #1/A ALA 112 HN -0.339 3.219
|
|---|
| 8625 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A ILE 108 2HD1 -0.352 3.112
|
|---|
| 8626 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A LEU 236 2HD1 -0.353 3.233
|
|---|
| 8627 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A SER 182 O -0.357 3.597
|
|---|
| 8628 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A GLY 114 O -0.359 3.599
|
|---|
| 8629 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A ILE 108 CD1 -0.382 3.842
|
|---|
| 8630 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A VAL 116 3HG2 -0.398 3.008
|
|---|
| 8631 | 3ALN--WRM-16.result.pdbqt #2.1/? UNL 1 C 3ALN.pdbqt #1/A ALA 129 HB3 -0.400 3.280
|
|---|
| 8632 |
|
|---|
| 8633 |
|
|---|
| 8634 |
|
|---|
| 8635 | 50 contacts
|
|---|
| 8636 |
|
|---|
| 8637 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 8638 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3ALN--
|
|---|
| 8639 | > WRM-16.hbonds.txt
|
|---|
| 8640 |
|
|---|
| 8641 | The following atoms were skipped as donors/acceptors due to missing heavy-atom
|
|---|
| 8642 | bond partners: 3ALN.pdbqt #1/A PRO 308 N
|
|---|
| 8643 |
|
|---|
| 8644 |
|
|---|
| 8645 |
|
|---|
| 8646 | Finding intermodel H-bonds
|
|---|
| 8647 | Finding intramodel H-bonds
|
|---|
| 8648 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 8649 | Models used:
|
|---|
| 8650 | 1 3ALN.pdbqt
|
|---|
| 8651 | 2.1 3ALN--WRM-16.result.pdbqt
|
|---|
| 8652 |
|
|---|
| 8653 | 0 H-bonds
|
|---|
| 8654 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 8655 |
|
|---|
| 8656 |
|
|---|
| 8657 |
|
|---|
| 8658 | 0 hydrogen bonds found
|
|---|
| 8659 |
|
|---|
| 8660 | > select :UNL
|
|---|
| 8661 |
|
|---|
| 8662 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 8663 |
|
|---|
| 8664 | > label sel text "Ligand "
|
|---|
| 8665 |
|
|---|
| 8666 | > label height 1
|
|---|
| 8667 |
|
|---|
| 8668 | > ~select
|
|---|
| 8669 |
|
|---|
| 8670 | Nothing selected
|
|---|
| 8671 |
|
|---|
| 8672 | > 2dlabels text "Binding Energy: -8.7 kcal/mol" color red size 18 xpos .03
|
|---|
| 8673 | > ypos .95
|
|---|
| 8674 |
|
|---|
| 8675 | > 2dlabels text "3ALN WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 8676 |
|
|---|
| 8677 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3ALN--
|
|---|
| 8678 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 8679 | > true
|
|---|
| 8680 |
|
|---|
| 8681 | > select :UNL
|
|---|
| 8682 |
|
|---|
| 8683 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 8684 |
|
|---|
| 8685 | > view sel
|
|---|
| 8686 |
|
|---|
| 8687 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/3ALN--
|
|---|
| 8688 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 8689 | > true
|
|---|
| 8690 |
|
|---|
| 8691 | > close
|
|---|
| 8692 |
|
|---|
| 8693 | > wait 5
|
|---|
| 8694 |
|
|---|
| 8695 | > set bgColor white
|
|---|
| 8696 |
|
|---|
| 8697 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1BJ8.pdbqt
|
|---|
| 8698 |
|
|---|
| 8699 | Chain information for 1BJ8.pdbqt #1
|
|---|
| 8700 | ---
|
|---|
| 8701 | Chain | Description
|
|---|
| 8702 | A | No description available
|
|---|
| 8703 |
|
|---|
| 8704 | Opened 1BJ8.pdbqt containing 1 structures (1763 atoms, 1786 bonds)
|
|---|
| 8705 |
|
|---|
| 8706 | > wait 5
|
|---|
| 8707 |
|
|---|
| 8708 | > hide surfaces
|
|---|
| 8709 |
|
|---|
| 8710 | > hide atoms
|
|---|
| 8711 |
|
|---|
| 8712 | > show cartoons
|
|---|
| 8713 |
|
|---|
| 8714 | > wait 5
|
|---|
| 8715 |
|
|---|
| 8716 | > addh
|
|---|
| 8717 |
|
|---|
| 8718 | Summary of feedback from adding hydrogens to 1BJ8.pdbqt #1
|
|---|
| 8719 | ---
|
|---|
| 8720 | notes | No usable SEQRES records for 1BJ8.pdbqt (#1) chain A; guessing termini
|
|---|
| 8721 | instead
|
|---|
| 8722 | Chain-initial residues that are actual N termini: /A MET 1
|
|---|
| 8723 | Chain-initial residues that are not actual N termini:
|
|---|
| 8724 | Chain-final residues that are actual C termini: /A ARG 109
|
|---|
| 8725 | Chain-final residues that are not actual C termini:
|
|---|
| 8726 | 53 hydrogen bonds
|
|---|
| 8727 | 1 hydrogens added
|
|---|
| 8728 |
|
|---|
| 8729 |
|
|---|
| 8730 | > wait 5
|
|---|
| 8731 |
|
|---|
| 8732 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1BJ8--
|
|---|
| 8733 | > WRM-16.result.pdbqt
|
|---|
| 8734 |
|
|---|
| 8735 | Summary of feedback from opening
|
|---|
| 8736 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1BJ8--WRM-16.result.pdbqt
|
|---|
| 8737 | ---
|
|---|
| 8738 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 8739 | REMARK VINA RESULT: -6.1 0.000 0.000
|
|---|
| 8740 |
|
|---|
| 8741 | Ignored bad PDB record found on line 3
|
|---|
| 8742 | REMARK 5 active torsions:
|
|---|
| 8743 |
|
|---|
| 8744 | Ignored bad PDB record found on line 4
|
|---|
| 8745 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 8746 |
|
|---|
| 8747 | Ignored bad PDB record found on line 5
|
|---|
| 8748 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 8749 |
|
|---|
| 8750 | Ignored bad PDB record found on line 6
|
|---|
| 8751 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 8752 |
|
|---|
| 8753 | 184 messages similar to the above omitted
|
|---|
| 8754 |
|
|---|
| 8755 | Opened 1BJ8--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 8756 | bonds)
|
|---|
| 8757 |
|
|---|
| 8758 | > wait 5
|
|---|
| 8759 |
|
|---|
| 8760 | > close #2.2-9
|
|---|
| 8761 |
|
|---|
| 8762 | > wait 5
|
|---|
| 8763 |
|
|---|
| 8764 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 8765 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1BJ8--
|
|---|
| 8766 | > WRM-16.contacts.txt
|
|---|
| 8767 |
|
|---|
| 8768 |
|
|---|
| 8769 | Allowed overlap: -0.4
|
|---|
| 8770 | H-bond overlap reduction: 0.4
|
|---|
| 8771 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 8772 | Detect intra-residue contacts: False
|
|---|
| 8773 | Detect intra-molecule contacts: True
|
|---|
| 8774 |
|
|---|
| 8775 | 46 contacts
|
|---|
| 8776 | atom1 atom2 overlap distance
|
|---|
| 8777 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TRP 94 HN 0.407 2.473
|
|---|
| 8778 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TRP 94 HD1 0.307 2.573
|
|---|
| 8779 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TRP 94 CD1 0.188 3.392
|
|---|
| 8780 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A LYS 5 HD2 0.101 2.659
|
|---|
| 8781 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A LYS 5 HD2 0.099 2.661
|
|---|
| 8782 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 O 1BJ8.pdbqt #1/A TRP 94 HD1 0.093 2.367
|
|---|
| 8783 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TRP 94 N 0.055 3.450
|
|---|
| 8784 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TRP 94 HB1 0.042 2.568
|
|---|
| 8785 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TYR 93 HA 0.032 2.848
|
|---|
| 8786 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1BJ8.pdbqt #1/A TYR 93 HE1 0.021 2.859
|
|---|
| 8787 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A ARG 84 1HH1 -0.035 2.915
|
|---|
| 8788 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TYR 93 HD1 -0.079 2.959
|
|---|
| 8789 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1BJ8.pdbqt #1/A TYR 93 CE1 -0.079 3.659
|
|---|
| 8790 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TRP 94 HD1 -0.085 2.965
|
|---|
| 8791 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A GLY 92 O -0.136 3.496
|
|---|
| 8792 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A LYS 3 CG -0.149 3.609
|
|---|
| 8793 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A LYS 5 CD -0.166 3.626
|
|---|
| 8794 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TRP 94 HD1 -0.172 2.782
|
|---|
| 8795 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TRP 94 O -0.174 3.264
|
|---|
| 8796 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 O 1BJ8.pdbqt #1/A ARG 84 1HH1 -0.175 2.235
|
|---|
| 8797 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TYR 93 CE1 -0.177 3.487
|
|---|
| 8798 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TRP 94 HB1 -0.200 2.810
|
|---|
| 8799 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TYR 93 HE1 -0.226 2.836
|
|---|
| 8800 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TRP 94 O -0.231 3.471
|
|---|
| 8801 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A LYS 3 CB -0.254 3.714
|
|---|
| 8802 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A GLY 92 O -0.270 3.510
|
|---|
| 8803 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TYR 93 CE1 -0.273 3.733
|
|---|
| 8804 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TYR 93 CA -0.283 3.863
|
|---|
| 8805 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 O 1BJ8.pdbqt #1/A TRP 94 CD1 -0.288 3.448
|
|---|
| 8806 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A LYS 5 HZ2 -0.299 3.059
|
|---|
| 8807 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A LYS 3 HG2 -0.302 3.062
|
|---|
| 8808 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A LYS 5 CD -0.307 3.767
|
|---|
| 8809 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A LYS 91 O -0.315 3.555
|
|---|
| 8810 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 O 1BJ8.pdbqt #1/A TYR 93 HB2 -0.317 2.777
|
|---|
| 8811 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 O 1BJ8.pdbqt #1/A ARG 84 NH1 -0.328 3.013
|
|---|
| 8812 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TRP 94 HB1 -0.331 2.941
|
|---|
| 8813 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A LYS 3 CD -0.332 3.792
|
|---|
| 8814 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 O 1BJ8.pdbqt #1/A TYR 93 HD1 -0.338 2.798
|
|---|
| 8815 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A LYS 3 HD2 -0.347 3.107
|
|---|
| 8816 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TRP 94 CD1 -0.352 3.662
|
|---|
| 8817 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 O 1BJ8.pdbqt #1/A ARG 84 CZ -0.358 3.478
|
|---|
| 8818 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 O 1BJ8.pdbqt #1/A TYR 93 CB -0.364 3.524
|
|---|
| 8819 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TRP 94 CB -0.372 3.682
|
|---|
| 8820 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A ARG 84 NH1 -0.385 3.890
|
|---|
| 8821 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 O 1BJ8.pdbqt #1/A TYR 93 CA -0.392 3.552
|
|---|
| 8822 | 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 C 1BJ8.pdbqt #1/A TRP 94 O -0.399 3.489
|
|---|
| 8823 |
|
|---|
| 8824 |
|
|---|
| 8825 |
|
|---|
| 8826 | 46 contacts
|
|---|
| 8827 |
|
|---|
| 8828 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 8829 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1BJ8--
|
|---|
| 8830 | > WRM-16.hbonds.txt
|
|---|
| 8831 |
|
|---|
| 8832 |
|
|---|
| 8833 | Finding intermodel H-bonds
|
|---|
| 8834 | Finding intramodel H-bonds
|
|---|
| 8835 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 8836 | Models used:
|
|---|
| 8837 | 1 1BJ8.pdbqt
|
|---|
| 8838 | 2.1 1BJ8--WRM-16.result.pdbqt
|
|---|
| 8839 |
|
|---|
| 8840 | 1 H-bonds
|
|---|
| 8841 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 8842 | 1BJ8.pdbqt #1/A ARG 84 NH1 1BJ8--WRM-16.result.pdbqt #2.1/? UNL 1 O 1BJ8.pdbqt #1/A ARG 84 1HH1 3.013 2.235
|
|---|
| 8843 |
|
|---|
| 8844 |
|
|---|
| 8845 |
|
|---|
| 8846 | 1 hydrogen bonds found
|
|---|
| 8847 |
|
|---|
| 8848 | > select :UNL
|
|---|
| 8849 |
|
|---|
| 8850 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 8851 |
|
|---|
| 8852 | > label sel text "Ligand "
|
|---|
| 8853 |
|
|---|
| 8854 | > label height 1
|
|---|
| 8855 |
|
|---|
| 8856 | > ~select
|
|---|
| 8857 |
|
|---|
| 8858 | Nothing selected
|
|---|
| 8859 |
|
|---|
| 8860 | > 2dlabels text "Binding Energy: -6.1 kcal/mol" color red size 18 xpos .03
|
|---|
| 8861 | > ypos .95
|
|---|
| 8862 |
|
|---|
| 8863 | > 2dlabels text "1BJ8 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 8864 |
|
|---|
| 8865 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1BJ8--
|
|---|
| 8866 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 8867 | > true
|
|---|
| 8868 |
|
|---|
| 8869 | > select :UNL
|
|---|
| 8870 |
|
|---|
| 8871 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 8872 |
|
|---|
| 8873 | > view sel
|
|---|
| 8874 |
|
|---|
| 8875 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1BJ8--
|
|---|
| 8876 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 8877 | > true
|
|---|
| 8878 |
|
|---|
| 8879 | > close
|
|---|
| 8880 |
|
|---|
| 8881 | > wait 5
|
|---|
| 8882 |
|
|---|
| 8883 | > set bgColor white
|
|---|
| 8884 |
|
|---|
| 8885 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/2LX7.pdbqt
|
|---|
| 8886 |
|
|---|
| 8887 | Chain information for 2LX7.pdbqt #1
|
|---|
| 8888 | ---
|
|---|
| 8889 | Chain | Description
|
|---|
| 8890 | A | No description available
|
|---|
| 8891 |
|
|---|
| 8892 | Opened 2LX7.pdbqt containing 1 structures (931 atoms, 945 bonds)
|
|---|
| 8893 |
|
|---|
| 8894 | > wait 5
|
|---|
| 8895 |
|
|---|
| 8896 | > hide surfaces
|
|---|
| 8897 |
|
|---|
| 8898 | > hide atoms
|
|---|
| 8899 |
|
|---|
| 8900 | > show cartoons
|
|---|
| 8901 |
|
|---|
| 8902 | > wait 5
|
|---|
| 8903 |
|
|---|
| 8904 | > addh
|
|---|
| 8905 |
|
|---|
| 8906 | Summary of feedback from adding hydrogens to 2LX7.pdbqt #1
|
|---|
| 8907 | ---
|
|---|
| 8908 | notes | No usable SEQRES records for 2LX7.pdbqt (#1) chain A; guessing termini
|
|---|
| 8909 | instead
|
|---|
| 8910 | Chain-initial residues that are actual N termini: /A MET 1
|
|---|
| 8911 | Chain-initial residues that are not actual N termini:
|
|---|
| 8912 | Chain-final residues that are actual C termini: /A LEU 60
|
|---|
| 8913 | Chain-final residues that are not actual C termini:
|
|---|
| 8914 | 24 hydrogen bonds
|
|---|
| 8915 | 0 hydrogens added
|
|---|
| 8916 |
|
|---|
| 8917 |
|
|---|
| 8918 | > wait 5
|
|---|
| 8919 |
|
|---|
| 8920 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2LX7--
|
|---|
| 8921 | > WRM-16.result.pdbqt
|
|---|
| 8922 |
|
|---|
| 8923 | Summary of feedback from opening
|
|---|
| 8924 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/2LX7--WRM-16.result.pdbqt
|
|---|
| 8925 | ---
|
|---|
| 8926 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 8927 | REMARK VINA RESULT: -7.2 0.000 0.000
|
|---|
| 8928 |
|
|---|
| 8929 | Ignored bad PDB record found on line 3
|
|---|
| 8930 | REMARK 5 active torsions:
|
|---|
| 8931 |
|
|---|
| 8932 | Ignored bad PDB record found on line 4
|
|---|
| 8933 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 8934 |
|
|---|
| 8935 | Ignored bad PDB record found on line 5
|
|---|
| 8936 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 8937 |
|
|---|
| 8938 | Ignored bad PDB record found on line 6
|
|---|
| 8939 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 8940 |
|
|---|
| 8941 | 184 messages similar to the above omitted
|
|---|
| 8942 |
|
|---|
| 8943 | Opened 2LX7--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 8944 | bonds)
|
|---|
| 8945 |
|
|---|
| 8946 | > wait 5
|
|---|
| 8947 |
|
|---|
| 8948 | > close #2.2-9
|
|---|
| 8949 |
|
|---|
| 8950 | > wait 5
|
|---|
| 8951 |
|
|---|
| 8952 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 8953 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2LX7--
|
|---|
| 8954 | > WRM-16.contacts.txt
|
|---|
| 8955 |
|
|---|
| 8956 |
|
|---|
| 8957 | Allowed overlap: -0.4
|
|---|
| 8958 | H-bond overlap reduction: 0.4
|
|---|
| 8959 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 8960 | Detect intra-residue contacts: False
|
|---|
| 8961 | Detect intra-molecule contacts: True
|
|---|
| 8962 |
|
|---|
| 8963 | 35 contacts
|
|---|
| 8964 | atom1 atom2 overlap distance
|
|---|
| 8965 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2LX7.pdbqt #1/A TRP 39 HH2 0.191 2.689
|
|---|
| 8966 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 O 2LX7.pdbqt #1/A TYR 56 HH 0.132 1.888
|
|---|
| 8967 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A PHE 52 HZ 0.130 2.750
|
|---|
| 8968 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A TRP 39 HH2 0.115 2.645
|
|---|
| 8969 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A TRP 51 O 0.112 3.128
|
|---|
| 8970 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A TYR 56 HE2 0.053 2.707
|
|---|
| 8971 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A PRO 53 HG3 0.042 2.718
|
|---|
| 8972 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A TYR 56 HH 0.010 2.600
|
|---|
| 8973 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 CL 2LX7.pdbqt #1/A TRP 39 CH2 -0.011 3.591
|
|---|
| 8974 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A PRO 53 HG3 -0.060 2.820
|
|---|
| 8975 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A TRP 39 CH2 -0.068 3.528
|
|---|
| 8976 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A GLY 20 HA3 -0.079 2.959
|
|---|
| 8977 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A PHE 52 CZ -0.105 3.685
|
|---|
| 8978 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 O 2LX7.pdbqt #1/A GLU 15 O -0.118 3.058
|
|---|
| 8979 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A GLY 20 CA -0.132 3.712
|
|---|
| 8980 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A TYR 56 CE2 -0.179 3.639
|
|---|
| 8981 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A TRP 51 CZ3 -0.207 3.787
|
|---|
| 8982 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A TRP 39 HH2 -0.232 2.842
|
|---|
| 8983 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A TRP 51 CH2 -0.241 3.821
|
|---|
| 8984 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A GLY 20 HA2 -0.243 3.003
|
|---|
| 8985 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 O 2LX7.pdbqt #1/A GLU 15 O -0.254 3.154
|
|---|
| 8986 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A PHE 52 CZ -0.296 3.606
|
|---|
| 8987 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 O 2LX7.pdbqt #1/A TYR 56 OH -0.300 2.820
|
|---|
| 8988 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A PRO 53 CG -0.319 3.779
|
|---|
| 8989 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A PRO 53 CG -0.323 3.783
|
|---|
| 8990 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A TYR 56 OH -0.323 3.583
|
|---|
| 8991 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A PHE 52 HE1 -0.324 2.934
|
|---|
| 8992 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A GLY 20 C -0.328 3.908
|
|---|
| 8993 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A TRP 39 CZ3 -0.350 3.810
|
|---|
| 8994 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 O 2LX7.pdbqt #1/A GLY 14 H -0.369 2.389
|
|---|
| 8995 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A GLY 20 CA -0.372 3.832
|
|---|
| 8996 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 O 2LX7.pdbqt #1/A SER 13 CB -0.376 3.496
|
|---|
| 8997 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A TYR 56 OH -0.387 3.497
|
|---|
| 8998 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A PHE 52 CE1 -0.391 3.701
|
|---|
| 8999 | 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 C 2LX7.pdbqt #1/A TYR 56 HE2 -0.398 3.008
|
|---|
| 9000 |
|
|---|
| 9001 |
|
|---|
| 9002 |
|
|---|
| 9003 | 35 contacts
|
|---|
| 9004 |
|
|---|
| 9005 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 9006 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2LX7--
|
|---|
| 9007 | > WRM-16.hbonds.txt
|
|---|
| 9008 |
|
|---|
| 9009 |
|
|---|
| 9010 | Finding intermodel H-bonds
|
|---|
| 9011 | Finding intramodel H-bonds
|
|---|
| 9012 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 9013 | Models used:
|
|---|
| 9014 | 1 2LX7.pdbqt
|
|---|
| 9015 | 2.1 2LX7--WRM-16.result.pdbqt
|
|---|
| 9016 |
|
|---|
| 9017 | 2 H-bonds
|
|---|
| 9018 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 9019 | 2LX7.pdbqt #1/A GLY 14 N 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 O 2LX7.pdbqt #1/A GLY 14 H 3.315 2.389
|
|---|
| 9020 | 2LX7.pdbqt #1/A TYR 56 OH 2LX7--WRM-16.result.pdbqt #2.1/? UNL 1 O 2LX7.pdbqt #1/A TYR 56 HH 2.820 1.888
|
|---|
| 9021 |
|
|---|
| 9022 |
|
|---|
| 9023 |
|
|---|
| 9024 | 2 hydrogen bonds found
|
|---|
| 9025 |
|
|---|
| 9026 | > select :UNL
|
|---|
| 9027 |
|
|---|
| 9028 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 9029 |
|
|---|
| 9030 | > label sel text "Ligand "
|
|---|
| 9031 |
|
|---|
| 9032 | > label height 1
|
|---|
| 9033 |
|
|---|
| 9034 | > ~select
|
|---|
| 9035 |
|
|---|
| 9036 | Nothing selected
|
|---|
| 9037 |
|
|---|
| 9038 | > 2dlabels text "Binding Energy: -7.2 kcal/mol" color red size 18 xpos .03
|
|---|
| 9039 | > ypos .95
|
|---|
| 9040 |
|
|---|
| 9041 | > 2dlabels text "2LX7 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 9042 |
|
|---|
| 9043 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2LX7--
|
|---|
| 9044 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 9045 | > true
|
|---|
| 9046 |
|
|---|
| 9047 | > select :UNL
|
|---|
| 9048 |
|
|---|
| 9049 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 9050 |
|
|---|
| 9051 | > view sel
|
|---|
| 9052 |
|
|---|
| 9053 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/2LX7--
|
|---|
| 9054 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 9055 | > true
|
|---|
| 9056 |
|
|---|
| 9057 | > close
|
|---|
| 9058 |
|
|---|
| 9059 | > wait 5
|
|---|
| 9060 |
|
|---|
| 9061 | > set bgColor white
|
|---|
| 9062 |
|
|---|
| 9063 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1SM3.pdbqt
|
|---|
| 9064 |
|
|---|
| 9065 | Chain information for 1SM3.pdbqt #1
|
|---|
| 9066 | ---
|
|---|
| 9067 | Chain | Description
|
|---|
| 9068 | H | No description available
|
|---|
| 9069 | L | No description available
|
|---|
| 9070 | P | No description available
|
|---|
| 9071 |
|
|---|
| 9072 | Opened 1SM3.pdbqt containing 1 structures (6388 atoms, 6469 bonds)
|
|---|
| 9073 |
|
|---|
| 9074 | > wait 5
|
|---|
| 9075 |
|
|---|
| 9076 | > hide surfaces
|
|---|
| 9077 |
|
|---|
| 9078 | > hide atoms
|
|---|
| 9079 |
|
|---|
| 9080 | > show cartoons
|
|---|
| 9081 |
|
|---|
| 9082 | > wait 5
|
|---|
| 9083 |
|
|---|
| 9084 | > addh
|
|---|
| 9085 |
|
|---|
| 9086 | Summary of feedback from adding hydrogens to 1SM3.pdbqt #1
|
|---|
| 9087 | ---
|
|---|
| 9088 | warnings | Not adding hydrogens to /L ASP 41 CB because it is missing heavy-
|
|---|
| 9089 | atom bond partners
|
|---|
| 9090 | Not adding hydrogens to /L GLU 123 CB because it is missing heavy-atom bond
|
|---|
| 9091 | partners
|
|---|
| 9092 | Not adding hydrogens to /L GLN 163 CB because it is missing heavy-atom bond
|
|---|
| 9093 | partners
|
|---|
| 9094 | Not adding hydrogens to /H GLN 1 CB because it is missing heavy-atom bond
|
|---|
| 9095 | partners
|
|---|
| 9096 | Not adding hydrogens to /H GLU 42 CB because it is missing heavy-atom bond
|
|---|
| 9097 | partners
|
|---|
| 9098 | 7 messages similar to the above omitted
|
|---|
| 9099 | notes | No usable SEQRES records for 1SM3.pdbqt (#1) chain H; guessing termini
|
|---|
| 9100 | instead
|
|---|
| 9101 | No usable SEQRES records for 1SM3.pdbqt (#1) chain L; guessing termini instead
|
|---|
| 9102 | No usable SEQRES records for 1SM3.pdbqt (#1) chain P; guessing termini instead
|
|---|
| 9103 | Chain-initial residues that are actual N termini: /H GLN 1, /L ILE 3, /P SER 2
|
|---|
| 9104 | Chain-initial residues that are not actual N termini: /H SER 134
|
|---|
| 9105 | Chain-final residues that are actual C termini: /H ARG 213, /L ARG 208, /P PRO
|
|---|
| 9106 | 10
|
|---|
| 9107 | Chain-final residues that are not actual C termini: /H GLY 127
|
|---|
| 9108 | 327 hydrogen bonds
|
|---|
| 9109 | Adding 'H' to /H SER 134
|
|---|
| 9110 | /H GLY 127 is not terminus, removing H atom from 'C'
|
|---|
| 9111 | 6 hydrogens added
|
|---|
| 9112 |
|
|---|
| 9113 |
|
|---|
| 9114 | > wait 5
|
|---|
| 9115 |
|
|---|
| 9116 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1SM3--
|
|---|
| 9117 | > WRM-16.result.pdbqt
|
|---|
| 9118 |
|
|---|
| 9119 | Summary of feedback from opening
|
|---|
| 9120 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1SM3--WRM-16.result.pdbqt
|
|---|
| 9121 | ---
|
|---|
| 9122 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 9123 | REMARK VINA RESULT: -7.7 0.000 0.000
|
|---|
| 9124 |
|
|---|
| 9125 | Ignored bad PDB record found on line 3
|
|---|
| 9126 | REMARK 5 active torsions:
|
|---|
| 9127 |
|
|---|
| 9128 | Ignored bad PDB record found on line 4
|
|---|
| 9129 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 9130 |
|
|---|
| 9131 | Ignored bad PDB record found on line 5
|
|---|
| 9132 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 9133 |
|
|---|
| 9134 | Ignored bad PDB record found on line 6
|
|---|
| 9135 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 9136 |
|
|---|
| 9137 | 184 messages similar to the above omitted
|
|---|
| 9138 |
|
|---|
| 9139 | Opened 1SM3--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 9140 | bonds)
|
|---|
| 9141 |
|
|---|
| 9142 | > wait 5
|
|---|
| 9143 |
|
|---|
| 9144 | > close #2.2-9
|
|---|
| 9145 |
|
|---|
| 9146 | > wait 5
|
|---|
| 9147 |
|
|---|
| 9148 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 9149 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1SM3--
|
|---|
| 9150 | > WRM-16.contacts.txt
|
|---|
| 9151 |
|
|---|
| 9152 |
|
|---|
| 9153 | Allowed overlap: -0.4
|
|---|
| 9154 | H-bond overlap reduction: 0.4
|
|---|
| 9155 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 9156 | Detect intra-residue contacts: False
|
|---|
| 9157 | Detect intra-molecule contacts: True
|
|---|
| 9158 |
|
|---|
| 9159 | 44 contacts
|
|---|
| 9160 | atom1 atom2 overlap distance
|
|---|
| 9161 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/H LEU 45 O 0.370 2.990
|
|---|
| 9162 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/H GLU 61 HN 0.367 2.393
|
|---|
| 9163 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L VAL 97 2HG1 0.353 2.257
|
|---|
| 9164 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L VAL 4 3HG2 0.128 2.632
|
|---|
| 9165 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/H GLU 61 N 0.075 3.310
|
|---|
| 9166 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 O 1SM3.pdbqt #1/L VAL 97 2HG1 0.056 2.404
|
|---|
| 9167 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/H GLU 61 HN 0.000 2.610
|
|---|
| 9168 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 O 1SM3.pdbqt #1/H ALA 60 HB1 -0.008 2.428
|
|---|
| 9169 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/H ALA 60 HA -0.009 2.769
|
|---|
| 9170 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 O 1SM3.pdbqt #1/H TRP 47 HN -0.048 2.068
|
|---|
| 9171 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L VAL 97 CG1 -0.053 3.363
|
|---|
| 9172 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L VAL 97 3HG2 -0.115 2.995
|
|---|
| 9173 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L HIS 95 ND1 -0.116 3.501
|
|---|
| 9174 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L HIS 95 HD1 -0.124 3.004
|
|---|
| 9175 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 O 1SM3.pdbqt #1/H GLU 46 HA -0.129 2.549
|
|---|
| 9176 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L VAL 97 2HG1 -0.148 2.758
|
|---|
| 9177 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L VAL 4 3HG2 -0.173 2.933
|
|---|
| 9178 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L ILE 3 O -0.179 3.419
|
|---|
| 9179 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L HIS 95 CG -0.185 3.645
|
|---|
| 9180 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/H GLU 61 HN -0.187 2.797
|
|---|
| 9181 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 O 1SM3.pdbqt #1/L VAL 97 HA -0.215 2.635
|
|---|
| 9182 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L ILE 3 O -0.217 3.457
|
|---|
| 9183 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L VAL 97 2HG1 -0.234 2.844
|
|---|
| 9184 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L HIS 95 CE1 -0.246 3.706
|
|---|
| 9185 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 O 1SM3.pdbqt #1/L VAL 97 CG1 -0.256 3.416
|
|---|
| 9186 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L HIS 95 CG -0.264 3.724
|
|---|
| 9187 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L VAL 97 HA -0.282 2.892
|
|---|
| 9188 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L VAL 4 CG2 -0.283 3.743
|
|---|
| 9189 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/H ALA 60 CA -0.291 3.751
|
|---|
| 9190 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L HIS 95 CE1 -0.319 3.779
|
|---|
| 9191 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 O 1SM3.pdbqt #1/H ALA 60 CB -0.325 3.445
|
|---|
| 9192 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 O 1SM3.pdbqt #1/L PHE 98 O -0.325 3.265
|
|---|
| 9193 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L HIS 95 ND1 -0.328 3.713
|
|---|
| 9194 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/H GLU 46 HG1 -0.347 2.957
|
|---|
| 9195 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/H GLU 46 CG -0.354 3.664
|
|---|
| 9196 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/H TRP 47 HN -0.354 2.964
|
|---|
| 9197 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/H GLU 46 HG2 -0.363 3.243
|
|---|
| 9198 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L HIS 95 ND1 -0.366 3.601
|
|---|
| 9199 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L HIS 95 ND1 -0.369 3.874
|
|---|
| 9200 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L VAL 97 CG1 -0.375 3.685
|
|---|
| 9201 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L VAL 4 HA -0.380 3.140
|
|---|
| 9202 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/H GLU 61 N -0.390 3.625
|
|---|
| 9203 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 C 1SM3.pdbqt #1/L VAL 97 CG2 -0.393 3.973
|
|---|
| 9204 | 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 O 1SM3.pdbqt #1/H GLU 46 CA -0.398 3.518
|
|---|
| 9205 |
|
|---|
| 9206 |
|
|---|
| 9207 |
|
|---|
| 9208 | 44 contacts
|
|---|
| 9209 |
|
|---|
| 9210 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 9211 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1SM3--
|
|---|
| 9212 | > WRM-16.hbonds.txt
|
|---|
| 9213 |
|
|---|
| 9214 |
|
|---|
| 9215 | Finding intermodel H-bonds
|
|---|
| 9216 | Finding intramodel H-bonds
|
|---|
| 9217 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 9218 | Models used:
|
|---|
| 9219 | 1 1SM3.pdbqt
|
|---|
| 9220 | 2.1 1SM3--WRM-16.result.pdbqt
|
|---|
| 9221 |
|
|---|
| 9222 | 1 H-bonds
|
|---|
| 9223 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 9224 | 1SM3.pdbqt #1/H TRP 47 N 1SM3--WRM-16.result.pdbqt #2.1/? UNL 1 O 1SM3.pdbqt #1/H TRP 47 HN 3.052 2.068
|
|---|
| 9225 |
|
|---|
| 9226 |
|
|---|
| 9227 |
|
|---|
| 9228 | 1 hydrogen bonds found
|
|---|
| 9229 |
|
|---|
| 9230 | > select :UNL
|
|---|
| 9231 |
|
|---|
| 9232 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 9233 |
|
|---|
| 9234 | > label sel text "Ligand "
|
|---|
| 9235 |
|
|---|
| 9236 | > label height 1
|
|---|
| 9237 |
|
|---|
| 9238 | > ~select
|
|---|
| 9239 |
|
|---|
| 9240 | Nothing selected
|
|---|
| 9241 |
|
|---|
| 9242 | > 2dlabels text "Binding Energy: -7.7 kcal/mol" color red size 18 xpos .03
|
|---|
| 9243 | > ypos .95
|
|---|
| 9244 |
|
|---|
| 9245 | > 2dlabels text "1SM3 WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 9246 |
|
|---|
| 9247 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1SM3--
|
|---|
| 9248 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 9249 | > true
|
|---|
| 9250 |
|
|---|
| 9251 | > select :UNL
|
|---|
| 9252 |
|
|---|
| 9253 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 9254 |
|
|---|
| 9255 | > view sel
|
|---|
| 9256 |
|
|---|
| 9257 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1SM3--
|
|---|
| 9258 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 9259 | > true
|
|---|
| 9260 |
|
|---|
| 9261 | > close
|
|---|
| 9262 |
|
|---|
| 9263 | > wait 5
|
|---|
| 9264 |
|
|---|
| 9265 | > set bgColor white
|
|---|
| 9266 |
|
|---|
| 9267 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1RRP.pdbqt
|
|---|
| 9268 |
|
|---|
| 9269 | Chain information for 1RRP.pdbqt #1
|
|---|
| 9270 | ---
|
|---|
| 9271 | Chain | Description
|
|---|
| 9272 | A | No description available
|
|---|
| 9273 | B D | No description available
|
|---|
| 9274 | C | No description available
|
|---|
| 9275 |
|
|---|
| 9276 | Opened 1RRP.pdbqt containing 1 structures (10655 atoms, 10785 bonds)
|
|---|
| 9277 |
|
|---|
| 9278 | > wait 5
|
|---|
| 9279 |
|
|---|
| 9280 | > hide surfaces
|
|---|
| 9281 |
|
|---|
| 9282 | > hide atoms
|
|---|
| 9283 |
|
|---|
| 9284 | > show cartoons
|
|---|
| 9285 |
|
|---|
| 9286 | > wait 5
|
|---|
| 9287 |
|
|---|
| 9288 | > addh
|
|---|
| 9289 |
|
|---|
| 9290 | Summary of feedback from adding hydrogens to 1RRP.pdbqt #1
|
|---|
| 9291 | ---
|
|---|
| 9292 | notes | No usable SEQRES records for 1RRP.pdbqt (#1) chain A; guessing termini
|
|---|
| 9293 | instead
|
|---|
| 9294 | No usable SEQRES records for 1RRP.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 9295 | No usable SEQRES records for 1RRP.pdbqt (#1) chain C; guessing termini instead
|
|---|
| 9296 | No usable SEQRES records for 1RRP.pdbqt (#1) chain D; guessing termini instead
|
|---|
| 9297 | Chain-initial residues that are actual N termini: /A GLN 8, /B HIS 17, /C GLN
|
|---|
| 9298 | 8, /D HIS 17
|
|---|
| 9299 | Chain-initial residues that are not actual N termini:
|
|---|
| 9300 | Chain-final residues that are actual C termini: /A ASP 211, /B ILE 150, /C VAL
|
|---|
| 9301 | 187, /D ILE 150
|
|---|
| 9302 | Chain-final residues that are not actual C termini:
|
|---|
| 9303 | 454 hydrogen bonds
|
|---|
| 9304 | 12 hydrogens added
|
|---|
| 9305 |
|
|---|
| 9306 |
|
|---|
| 9307 | > wait 5
|
|---|
| 9308 |
|
|---|
| 9309 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1RRP--
|
|---|
| 9310 | > WRM-16.result.pdbqt
|
|---|
| 9311 |
|
|---|
| 9312 | Summary of feedback from opening
|
|---|
| 9313 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1RRP--WRM-16.result.pdbqt
|
|---|
| 9314 | ---
|
|---|
| 9315 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 9316 | REMARK VINA RESULT: -7.9 0.000 0.000
|
|---|
| 9317 |
|
|---|
| 9318 | Ignored bad PDB record found on line 3
|
|---|
| 9319 | REMARK 5 active torsions:
|
|---|
| 9320 |
|
|---|
| 9321 | Ignored bad PDB record found on line 4
|
|---|
| 9322 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 9323 |
|
|---|
| 9324 | Ignored bad PDB record found on line 5
|
|---|
| 9325 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 9326 |
|
|---|
| 9327 | Ignored bad PDB record found on line 6
|
|---|
| 9328 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 9329 |
|
|---|
| 9330 | 184 messages similar to the above omitted
|
|---|
| 9331 |
|
|---|
| 9332 | Opened 1RRP--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 9333 | bonds)
|
|---|
| 9334 |
|
|---|
| 9335 | > wait 5
|
|---|
| 9336 |
|
|---|
| 9337 | > close #2.2-9
|
|---|
| 9338 |
|
|---|
| 9339 | > wait 5
|
|---|
| 9340 |
|
|---|
| 9341 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 9342 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1RRP--
|
|---|
| 9343 | > WRM-16.contacts.txt
|
|---|
| 9344 |
|
|---|
| 9345 |
|
|---|
| 9346 | Allowed overlap: -0.4
|
|---|
| 9347 | H-bond overlap reduction: 0.4
|
|---|
| 9348 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 9349 | Detect intra-residue contacts: False
|
|---|
| 9350 | Detect intra-molecule contacts: True
|
|---|
| 9351 |
|
|---|
| 9352 | 73 contacts
|
|---|
| 9353 | atom1 atom2 overlap distance
|
|---|
| 9354 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ASN 122 1HD2 0.550 2.210
|
|---|
| 9355 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ALA 151 HB2 0.329 2.431
|
|---|
| 9356 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C GLY 22 HA2 0.286 2.594
|
|---|
| 9357 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ASN 122 ND2 0.178 3.207
|
|---|
| 9358 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C GLY 22 CA 0.103 3.477
|
|---|
| 9359 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C PHE 35 HZ 0.101 2.509
|
|---|
| 9360 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ASN 122 1HD2 0.066 2.694
|
|---|
| 9361 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C PHE 35 HE1 0.052 2.708
|
|---|
| 9362 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ILE 126 2HD1 0.026 2.734
|
|---|
| 9363 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C PHE 35 HZ 0.015 2.745
|
|---|
| 9364 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 O 1RRP.pdbqt #1/C ILE 126 1HD1 0.006 2.454
|
|---|
| 9365 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C THR 25 HG1 -0.002 2.882
|
|---|
| 9366 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 152 HD2 -0.018 2.898
|
|---|
| 9367 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1RRP.pdbqt #1/C ILE 126 1HG2 -0.020 2.900
|
|---|
| 9368 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 152 HB2 -0.024 2.784
|
|---|
| 9369 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ALA 151 CB -0.043 3.503
|
|---|
| 9370 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ILE 126 2HD1 -0.053 2.663
|
|---|
| 9371 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ILE 126 2HD1 -0.087 2.847
|
|---|
| 9372 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C PHE 35 HZ -0.100 2.710
|
|---|
| 9373 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 HE2 -0.113 2.723
|
|---|
| 9374 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 HG2 -0.115 2.875
|
|---|
| 9375 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 HZ2 -0.120 2.730
|
|---|
| 9376 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C PHE 35 CE1 -0.126 3.586
|
|---|
| 9377 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 HA -0.140 2.900
|
|---|
| 9378 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 HZ2 -0.150 3.030
|
|---|
| 9379 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1RRP.pdbqt #1/C ILE 126 CG2 -0.172 3.752
|
|---|
| 9380 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 152 CD -0.173 3.753
|
|---|
| 9381 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 HZ1 -0.173 3.053
|
|---|
| 9382 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 152 HZ3 -0.182 3.062
|
|---|
| 9383 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 152 HB2 -0.189 2.949
|
|---|
| 9384 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 HE2 -0.193 3.073
|
|---|
| 9385 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 O 1RRP.pdbqt #1/C THR 25 HG1 -0.195 2.255
|
|---|
| 9386 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C PHE 35 CE1 -0.197 3.657
|
|---|
| 9387 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C THR 25 OG1 -0.198 3.578
|
|---|
| 9388 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C PHE 35 CZ -0.208 3.668
|
|---|
| 9389 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ILE 126 2HD1 -0.213 2.973
|
|---|
| 9390 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 CE -0.220 3.800
|
|---|
| 9391 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ILE 126 CD1 -0.220 3.680
|
|---|
| 9392 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 NZ -0.221 3.726
|
|---|
| 9393 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ILE 126 CD1 -0.225 3.685
|
|---|
| 9394 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 HE2 -0.232 2.992
|
|---|
| 9395 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ASP 125 OD1 -0.239 3.479
|
|---|
| 9396 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ASN 122 1HD2 -0.242 3.002
|
|---|
| 9397 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C PHE 35 CZ -0.254 3.564
|
|---|
| 9398 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 NZ -0.263 3.498
|
|---|
| 9399 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ILE 126 CD1 -0.264 3.724
|
|---|
| 9400 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ILE 126 CD1 -0.270 3.730
|
|---|
| 9401 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 HZ2 -0.272 2.882
|
|---|
| 9402 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ASN 122 ND2 -0.275 3.660
|
|---|
| 9403 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C PHE 35 HE1 -0.275 3.035
|
|---|
| 9404 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C PHE 35 CZ -0.277 3.587
|
|---|
| 9405 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 CE -0.281 3.591
|
|---|
| 9406 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 152 CB -0.282 3.742
|
|---|
| 9407 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 HG2 -0.293 3.053
|
|---|
| 9408 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C PHE 35 CZ -0.294 3.754
|
|---|
| 9409 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 152 NZ -0.297 3.802
|
|---|
| 9410 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C PHE 35 HZ -0.298 3.058
|
|---|
| 9411 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C GLY 22 N -0.311 3.816
|
|---|
| 9412 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ILE 126 2HD1 -0.319 3.079
|
|---|
| 9413 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 152 N -0.321 3.706
|
|---|
| 9414 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 CG -0.336 3.796
|
|---|
| 9415 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ILE 126 1HG2 -0.341 2.951
|
|---|
| 9416 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ILE 126 CD1 -0.346 3.656
|
|---|
| 9417 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 37 O -0.351 3.441
|
|---|
| 9418 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 CG -0.355 3.815
|
|---|
| 9419 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C ASP 125 OD1 -0.356 3.596
|
|---|
| 9420 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C PHE 35 HZ -0.358 3.118
|
|---|
| 9421 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C GLY 20 O -0.362 3.722
|
|---|
| 9422 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 O 1RRP.pdbqt #1/C ILE 126 CD1 -0.365 3.525
|
|---|
| 9423 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C PHE 35 CZ -0.372 3.832
|
|---|
| 9424 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 CD -0.385 3.845
|
|---|
| 9425 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 NZ -0.393 3.628
|
|---|
| 9426 | 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 C 1RRP.pdbqt #1/C LYS 123 HE2 -0.399 3.009
|
|---|
| 9427 |
|
|---|
| 9428 |
|
|---|
| 9429 |
|
|---|
| 9430 | 73 contacts
|
|---|
| 9431 |
|
|---|
| 9432 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 9433 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1RRP--
|
|---|
| 9434 | > WRM-16.hbonds.txt
|
|---|
| 9435 |
|
|---|
| 9436 |
|
|---|
| 9437 | Finding intermodel H-bonds
|
|---|
| 9438 | Finding intramodel H-bonds
|
|---|
| 9439 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 9440 | Models used:
|
|---|
| 9441 | 1 1RRP.pdbqt
|
|---|
| 9442 | 2.1 1RRP--WRM-16.result.pdbqt
|
|---|
| 9443 |
|
|---|
| 9444 | 1 H-bonds
|
|---|
| 9445 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 9446 | 1RRP.pdbqt #1/C THR 25 OG1 1RRP--WRM-16.result.pdbqt #2.1/? UNL 1 O 1RRP.pdbqt #1/C THR 25 HG1 3.164 2.255
|
|---|
| 9447 |
|
|---|
| 9448 |
|
|---|
| 9449 |
|
|---|
| 9450 | 1 hydrogen bonds found
|
|---|
| 9451 |
|
|---|
| 9452 | > select :UNL
|
|---|
| 9453 |
|
|---|
| 9454 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 9455 |
|
|---|
| 9456 | > label sel text "Ligand "
|
|---|
| 9457 |
|
|---|
| 9458 | > label height 1
|
|---|
| 9459 |
|
|---|
| 9460 | > ~select
|
|---|
| 9461 |
|
|---|
| 9462 | Nothing selected
|
|---|
| 9463 |
|
|---|
| 9464 | > 2dlabels text "Binding Energy: -7.9 kcal/mol" color red size 18 xpos .03
|
|---|
| 9465 | > ypos .95
|
|---|
| 9466 |
|
|---|
| 9467 | > 2dlabels text "1RRP WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 9468 |
|
|---|
| 9469 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1RRP--
|
|---|
| 9470 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 9471 | > true
|
|---|
| 9472 |
|
|---|
| 9473 | > select :UNL
|
|---|
| 9474 |
|
|---|
| 9475 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 9476 |
|
|---|
| 9477 | > view sel
|
|---|
| 9478 |
|
|---|
| 9479 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1RRP--
|
|---|
| 9480 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 9481 | > true
|
|---|
| 9482 |
|
|---|
| 9483 | > close
|
|---|
| 9484 |
|
|---|
| 9485 | > wait 5
|
|---|
| 9486 |
|
|---|
| 9487 | > set bgColor white
|
|---|
| 9488 |
|
|---|
| 9489 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1OQD.pdbqt
|
|---|
| 9490 |
|
|---|
| 9491 | Chain information for 1OQD.pdbqt #1
|
|---|
| 9492 | ---
|
|---|
| 9493 | Chain | Description
|
|---|
| 9494 | A B C D E F G H I J | No description available
|
|---|
| 9495 | K L M O P Q R | No description available
|
|---|
| 9496 | N | No description available
|
|---|
| 9497 |
|
|---|
| 9498 | Opened 1OQD.pdbqt containing 1 structures (27310 atoms, 27575 bonds)
|
|---|
| 9499 |
|
|---|
| 9500 | > wait 5
|
|---|
| 9501 |
|
|---|
| 9502 | > hide surfaces
|
|---|
| 9503 |
|
|---|
| 9504 | > hide atoms
|
|---|
| 9505 |
|
|---|
| 9506 | > show cartoons
|
|---|
| 9507 |
|
|---|
| 9508 | > wait 5
|
|---|
| 9509 |
|
|---|
| 9510 | > addh
|
|---|
| 9511 |
|
|---|
| 9512 | Summary of feedback from adding hydrogens to 1OQD.pdbqt #1
|
|---|
| 9513 | ---
|
|---|
| 9514 | notes | No usable SEQRES records for 1OQD.pdbqt (#1) chain A; guessing termini
|
|---|
| 9515 | instead
|
|---|
| 9516 | No usable SEQRES records for 1OQD.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 9517 | No usable SEQRES records for 1OQD.pdbqt (#1) chain C; guessing termini instead
|
|---|
| 9518 | No usable SEQRES records for 1OQD.pdbqt (#1) chain D; guessing termini instead
|
|---|
| 9519 | No usable SEQRES records for 1OQD.pdbqt (#1) chain E; guessing termini instead
|
|---|
| 9520 | 13 messages similar to the above omitted
|
|---|
| 9521 | Chain-initial residues that are actual N termini: /A VAL 1, /B VAL 1, /C VAL
|
|---|
| 9522 | 1, /D VAL 1, /E VAL 1, /F VAL 1, /G VAL 1, /H VAL 1, /I VAL 1, /J VAL 1, /K
|
|---|
| 9523 | CYS 1, /L CYS 1, /M CYS 1, /N CYS 1, /O CYS 1, /P CYS 1, /Q CYS 1, /R CYS 1
|
|---|
| 9524 | Chain-initial residues that are not actual N termini:
|
|---|
| 9525 | Chain-final residues that are actual C termini: /A LEU 144, /B LEU 144, /C LEU
|
|---|
| 9526 | 144, /D LEU 144, /E LEU 144, /F LEU 144, /G LEU 144, /H LEU 144, /I LEU 144,
|
|---|
| 9527 | /J LEU 144, /K THR 39, /L THR 39, /M THR 39, /N CYS 21, /O THR 39, /P THR 39,
|
|---|
| 9528 | /Q THR 39, /R THR 39
|
|---|
| 9529 | Chain-final residues that are not actual C termini:
|
|---|
| 9530 | 1396 hydrogen bonds
|
|---|
| 9531 | 76 hydrogens added
|
|---|
| 9532 |
|
|---|
| 9533 |
|
|---|
| 9534 | > wait 5
|
|---|
| 9535 |
|
|---|
| 9536 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1OQD--
|
|---|
| 9537 | > WRM-16.result.pdbqt
|
|---|
| 9538 |
|
|---|
| 9539 | Summary of feedback from opening
|
|---|
| 9540 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1OQD--WRM-16.result.pdbqt
|
|---|
| 9541 | ---
|
|---|
| 9542 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 9543 | REMARK VINA RESULT: -8.0 0.000 0.000
|
|---|
| 9544 |
|
|---|
| 9545 | Ignored bad PDB record found on line 3
|
|---|
| 9546 | REMARK 5 active torsions:
|
|---|
| 9547 |
|
|---|
| 9548 | Ignored bad PDB record found on line 4
|
|---|
| 9549 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 9550 |
|
|---|
| 9551 | Ignored bad PDB record found on line 5
|
|---|
| 9552 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 9553 |
|
|---|
| 9554 | Ignored bad PDB record found on line 6
|
|---|
| 9555 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 9556 |
|
|---|
| 9557 | 184 messages similar to the above omitted
|
|---|
| 9558 |
|
|---|
| 9559 | Opened 1OQD--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 9560 | bonds)
|
|---|
| 9561 |
|
|---|
| 9562 | > wait 5
|
|---|
| 9563 |
|
|---|
| 9564 | > close #2.2-9
|
|---|
| 9565 |
|
|---|
| 9566 | > wait 5
|
|---|
| 9567 |
|
|---|
| 9568 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 9569 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1OQD--
|
|---|
| 9570 | > WRM-16.contacts.txt
|
|---|
| 9571 |
|
|---|
| 9572 |
|
|---|
| 9573 | Allowed overlap: -0.4
|
|---|
| 9574 | H-bond overlap reduction: 0.4
|
|---|
| 9575 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 9576 | Detect intra-residue contacts: False
|
|---|
| 9577 | Detect intra-molecule contacts: True
|
|---|
| 9578 |
|
|---|
| 9579 | 59 contacts
|
|---|
| 9580 | atom1 atom2 overlap distance
|
|---|
| 9581 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C TYR 65 HB2 0.581 2.179
|
|---|
| 9582 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1OQD.pdbqt #1/B ASN 102 2HD2 0.325 2.555
|
|---|
| 9583 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C TYR 65 CB 0.263 3.197
|
|---|
| 9584 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1OQD.pdbqt #1/A ASN 94 HB1 0.221 2.659
|
|---|
| 9585 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1OQD.pdbqt #1/B ASN 102 ND2 0.083 3.422
|
|---|
| 9586 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OQD.pdbqt #1/B PRO 96 HA 0.046 2.374
|
|---|
| 9587 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/B PRO 96 HG2 0.043 2.717
|
|---|
| 9588 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/A THR 98 HG1 0.040 2.720
|
|---|
| 9589 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/A THR 98 HG1 0.021 2.739
|
|---|
| 9590 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1OQD.pdbqt #1/A ASN 94 O 0.012 3.348
|
|---|
| 9591 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C ASN 94 HB2 0.008 2.872
|
|---|
| 9592 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/A THR 98 OG1 -0.005 3.265
|
|---|
| 9593 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C MET 95 O -0.011 3.101
|
|---|
| 9594 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OQD.pdbqt #1/C GLU 97 HB2 -0.026 2.486
|
|---|
| 9595 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/B PRO 96 HG2 -0.055 2.665
|
|---|
| 9596 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C TYR 65 HB2 -0.060 2.820
|
|---|
| 9597 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/A PRO 96 HB1 -0.061 2.821
|
|---|
| 9598 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1OQD.pdbqt #1/A ASN 94 CB -0.062 3.642
|
|---|
| 9599 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C PRO 96 HA -0.072 2.682
|
|---|
| 9600 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/A PRO 96 HG1 -0.076 2.956
|
|---|
| 9601 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/A PRO 96 CB -0.091 3.551
|
|---|
| 9602 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/B PRO 96 HG2 -0.093 2.853
|
|---|
| 9603 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C MET 95 O -0.135 3.495
|
|---|
| 9604 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1OQD.pdbqt #1/B ASN 102 OD1 -0.141 3.501
|
|---|
| 9605 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C MET 95 C -0.144 3.724
|
|---|
| 9606 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OQD.pdbqt #1/A PRO 96 HB1 -0.150 2.610
|
|---|
| 9607 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C GLU 97 HN -0.158 2.768
|
|---|
| 9608 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C TYR 65 CA -0.160 3.620
|
|---|
| 9609 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C PRO 96 HA -0.168 2.778
|
|---|
| 9610 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/B PRO 96 HG2 -0.196 2.956
|
|---|
| 9611 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OQD.pdbqt #1/B PRO 96 CA -0.202 3.322
|
|---|
| 9612 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C TYR 65 HA -0.204 2.964
|
|---|
| 9613 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C MET 95 O -0.212 3.452
|
|---|
| 9614 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/A ASN 94 HB2 -0.215 2.975
|
|---|
| 9615 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C ASN 94 CB -0.218 3.798
|
|---|
| 9616 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C MET 95 O -0.248 3.338
|
|---|
| 9617 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OQD.pdbqt #1/A PRO 96 CB -0.254 3.414
|
|---|
| 9618 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/B ASN 94 O -0.260 3.500
|
|---|
| 9619 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C PRO 96 HA -0.262 3.142
|
|---|
| 9620 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/A ASN 94 CB -0.270 3.730
|
|---|
| 9621 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1OQD.pdbqt #1/B ASN 102 CG -0.275 3.855
|
|---|
| 9622 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C TYR 65 O -0.277 3.517
|
|---|
| 9623 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/A THR 98 OG1 -0.281 3.541
|
|---|
| 9624 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/B PRO 96 CA -0.285 3.745
|
|---|
| 9625 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C ASN 94 HB2 -0.287 3.047
|
|---|
| 9626 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/A PRO 96 CG -0.291 3.751
|
|---|
| 9627 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C TYR 65 CB -0.306 3.766
|
|---|
| 9628 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/B PRO 96 HG2 -0.316 3.076
|
|---|
| 9629 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/B PRO 96 CG -0.318 3.778
|
|---|
| 9630 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/B PRO 96 HA -0.322 3.082
|
|---|
| 9631 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/A PRO 96 CG -0.332 3.912
|
|---|
| 9632 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/B PRO 96 CG -0.340 3.800
|
|---|
| 9633 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C MET 95 O -0.340 3.430
|
|---|
| 9634 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OQD.pdbqt #1/C GLU 97 CB -0.345 3.465
|
|---|
| 9635 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OQD.pdbqt #1/A PRO 96 CG -0.346 3.506
|
|---|
| 9636 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/C GLU 97 OE1 -0.350 3.710
|
|---|
| 9637 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 O 1OQD.pdbqt #1/A PRO 96 HG1 -0.351 2.811
|
|---|
| 9638 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/B MET 95 C -0.360 3.820
|
|---|
| 9639 | 1OQD--WRM-16.result.pdbqt #2.1/? UNL 1 C 1OQD.pdbqt #1/B PRO 96 CG -0.383 3.843
|
|---|
| 9640 |
|
|---|
| 9641 |
|
|---|
| 9642 |
|
|---|
| 9643 | 59 contacts
|
|---|
| 9644 |
|
|---|
| 9645 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 9646 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1OQD--
|
|---|
| 9647 | > WRM-16.hbonds.txt
|
|---|
| 9648 |
|
|---|
| 9649 |
|
|---|
| 9650 | Finding intermodel H-bonds
|
|---|
| 9651 | Finding intramodel H-bonds
|
|---|
| 9652 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 9653 | Models used:
|
|---|
| 9654 | 1 1OQD.pdbqt
|
|---|
| 9655 | 2.1 1OQD--WRM-16.result.pdbqt
|
|---|
| 9656 |
|
|---|
| 9657 | 0 H-bonds
|
|---|
| 9658 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 9659 |
|
|---|
| 9660 |
|
|---|
| 9661 |
|
|---|
| 9662 | 0 hydrogen bonds found
|
|---|
| 9663 |
|
|---|
| 9664 | > select :UNL
|
|---|
| 9665 |
|
|---|
| 9666 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 9667 |
|
|---|
| 9668 | > label sel text "Ligand "
|
|---|
| 9669 |
|
|---|
| 9670 | > label height 1
|
|---|
| 9671 |
|
|---|
| 9672 | > ~select
|
|---|
| 9673 |
|
|---|
| 9674 | Nothing selected
|
|---|
| 9675 |
|
|---|
| 9676 | > 2dlabels text "Binding Energy: -8.0 kcal/mol" color red size 18 xpos .03
|
|---|
| 9677 | > ypos .95
|
|---|
| 9678 |
|
|---|
| 9679 | > 2dlabels text "1OQD WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 9680 |
|
|---|
| 9681 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1OQD--
|
|---|
| 9682 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 9683 | > true
|
|---|
| 9684 |
|
|---|
| 9685 | > select :UNL
|
|---|
| 9686 |
|
|---|
| 9687 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 9688 |
|
|---|
| 9689 | > view sel
|
|---|
| 9690 |
|
|---|
| 9691 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1OQD--
|
|---|
| 9692 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 9693 | > true
|
|---|
| 9694 |
|
|---|
| 9695 | > close
|
|---|
| 9696 |
|
|---|
| 9697 | > wait 5
|
|---|
| 9698 |
|
|---|
| 9699 | > set bgColor white
|
|---|
| 9700 |
|
|---|
| 9701 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1S9J.pdbqt
|
|---|
| 9702 |
|
|---|
| 9703 | Chain information for 1S9J.pdbqt #1
|
|---|
| 9704 | ---
|
|---|
| 9705 | Chain | Description
|
|---|
| 9706 | A | No description available
|
|---|
| 9707 |
|
|---|
| 9708 | Opened 1S9J.pdbqt containing 1 structures (4567 atoms, 4613 bonds)
|
|---|
| 9709 |
|
|---|
| 9710 | > wait 5
|
|---|
| 9711 |
|
|---|
| 9712 | > hide surfaces
|
|---|
| 9713 |
|
|---|
| 9714 | > hide atoms
|
|---|
| 9715 |
|
|---|
| 9716 | > show cartoons
|
|---|
| 9717 |
|
|---|
| 9718 | > wait 5
|
|---|
| 9719 |
|
|---|
| 9720 | > addh
|
|---|
| 9721 |
|
|---|
| 9722 | Summary of feedback from adding hydrogens to 1S9J.pdbqt #1
|
|---|
| 9723 | ---
|
|---|
| 9724 | notes | No usable SEQRES records for 1S9J.pdbqt (#1) chain A; guessing termini
|
|---|
| 9725 | instead
|
|---|
| 9726 | Chain-initial residues that are actual N termini: /A MET 61
|
|---|
| 9727 | Chain-initial residues that are not actual N termini: /A VAL 224, /A PRO 306
|
|---|
| 9728 | Chain-final residues that are actual C termini: /A ASN 382
|
|---|
| 9729 | Chain-final residues that are not actual C termini: /A ALA 220, /A PHE 275
|
|---|
| 9730 | 207 hydrogen bonds
|
|---|
| 9731 | Adding 'H' to /A VAL 224
|
|---|
| 9732 | /A ALA 220 is not terminus, removing H atom from 'C'
|
|---|
| 9733 | /A PHE 275 is not terminus, removing H atom from 'C'
|
|---|
| 9734 | -1 hydrogens added
|
|---|
| 9735 |
|
|---|
| 9736 |
|
|---|
| 9737 | > wait 5
|
|---|
| 9738 |
|
|---|
| 9739 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1S9J--
|
|---|
| 9740 | > WRM-16.result.pdbqt
|
|---|
| 9741 |
|
|---|
| 9742 | Summary of feedback from opening
|
|---|
| 9743 | /home/vishalkumarsahu/Desktop/DGE8-2-Docking/docking/1S9J--WRM-16.result.pdbqt
|
|---|
| 9744 | ---
|
|---|
| 9745 | warnings | Ignored bad PDB record found on line 2
|
|---|
| 9746 | REMARK VINA RESULT: -9.2 0.000 0.000
|
|---|
| 9747 |
|
|---|
| 9748 | Ignored bad PDB record found on line 3
|
|---|
| 9749 | REMARK 5 active torsions:
|
|---|
| 9750 |
|
|---|
| 9751 | Ignored bad PDB record found on line 4
|
|---|
| 9752 | REMARK status: ('A' for Active; 'I' for Inactive)
|
|---|
| 9753 |
|
|---|
| 9754 | Ignored bad PDB record found on line 5
|
|---|
| 9755 | REMARK 1 A between atoms: C_9 and O_15
|
|---|
| 9756 |
|
|---|
| 9757 | Ignored bad PDB record found on line 6
|
|---|
| 9758 | REMARK 2 A between atoms: C_10 and O_17
|
|---|
| 9759 |
|
|---|
| 9760 | 184 messages similar to the above omitted
|
|---|
| 9761 |
|
|---|
| 9762 | Opened 1S9J--WRM-16.result.pdbqt containing 9 structures (252 atoms, 279
|
|---|
| 9763 | bonds)
|
|---|
| 9764 |
|
|---|
| 9765 | > wait 5
|
|---|
| 9766 |
|
|---|
| 9767 | > close #2.2-9
|
|---|
| 9768 |
|
|---|
| 9769 | > wait 5
|
|---|
| 9770 |
|
|---|
| 9771 | > contacts :UNL radius 0.05 log true saveFile
|
|---|
| 9772 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1S9J--
|
|---|
| 9773 | > WRM-16.contacts.txt
|
|---|
| 9774 |
|
|---|
| 9775 |
|
|---|
| 9776 | Allowed overlap: -0.4
|
|---|
| 9777 | H-bond overlap reduction: 0.4
|
|---|
| 9778 | Ignore contacts between atoms separated by 4 bonds or less
|
|---|
| 9779 | Detect intra-residue contacts: False
|
|---|
| 9780 | Detect intra-molecule contacts: True
|
|---|
| 9781 |
|
|---|
| 9782 | 47 contacts
|
|---|
| 9783 | atom1 atom2 overlap distance
|
|---|
| 9784 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A MET 146 HN 0.179 2.581
|
|---|
| 9785 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 O 1S9J.pdbqt #1/A VAL 82 1HG1 0.131 2.329
|
|---|
| 9786 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1S9J.pdbqt #1/A ASN 78 HB1 0.073 2.807
|
|---|
| 9787 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A GLY 149 HA1 0.062 2.818
|
|---|
| 9788 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A GLY 77 HA2 0.042 2.718
|
|---|
| 9789 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A LEU 74 HB2 0.034 2.846
|
|---|
| 9790 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A ALA 95 CB 0.029 3.431
|
|---|
| 9791 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A GLN 153 OE1 0.015 3.345
|
|---|
| 9792 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A LEU 197 1HD2 -0.055 2.815
|
|---|
| 9793 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A MET 143 HE1 -0.069 2.949
|
|---|
| 9794 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A LEU 197 CD2 -0.092 3.552
|
|---|
| 9795 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A LEU 74 O -0.118 3.478
|
|---|
| 9796 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A LYS 97 HE1 -0.119 2.999
|
|---|
| 9797 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A VAL 82 1HG2 -0.133 2.743
|
|---|
| 9798 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A LEU 197 CD2 -0.148 3.608
|
|---|
| 9799 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 O 1S9J.pdbqt #1/A GLY 149 HA1 -0.156 2.616
|
|---|
| 9800 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 O 1S9J.pdbqt #1/A LYS 97 CE -0.158 3.278
|
|---|
| 9801 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A ASP 208 OD2 -0.164 3.524
|
|---|
| 9802 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A GLY 149 CA -0.173 3.753
|
|---|
| 9803 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A MET 146 N -0.179 3.564
|
|---|
| 9804 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A MET 143 CE -0.181 3.761
|
|---|
| 9805 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A CYS 207 SG -0.191 3.853
|
|---|
| 9806 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A MET 143 SD -0.205 3.747
|
|---|
| 9807 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A SER 194 HG -0.211 2.971
|
|---|
| 9808 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A LEU 197 HG -0.219 2.979
|
|---|
| 9809 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 O 1S9J.pdbqt #1/A VAL 82 CG1 -0.246 3.406
|
|---|
| 9810 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A LEU 197 CD2 -0.247 3.707
|
|---|
| 9811 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A LEU 197 1HD2 -0.262 3.022
|
|---|
| 9812 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 O 1S9J.pdbqt #1/A SER 150 OG -0.269 2.789
|
|---|
| 9813 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1S9J.pdbqt #1/A ASN 78 CB -0.271 3.851
|
|---|
| 9814 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A GLY 77 O -0.279 3.519
|
|---|
| 9815 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A ASP 208 OD1 -0.291 3.651
|
|---|
| 9816 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A VAL 82 1HG2 -0.310 2.920
|
|---|
| 9817 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 O 1S9J.pdbqt #1/A LYS 97 HE2 -0.310 2.730
|
|---|
| 9818 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A LYS 97 CE -0.316 3.896
|
|---|
| 9819 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 O 1S9J.pdbqt #1/A GLY 149 CA -0.320 3.480
|
|---|
| 9820 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A GLY 77 HA2 -0.323 3.083
|
|---|
| 9821 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A GLY 77 HA2 -0.326 2.936
|
|---|
| 9822 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A LEU 197 CD2 -0.341 3.801
|
|---|
| 9823 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A LEU 74 CB -0.348 3.928
|
|---|
| 9824 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A GLY 77 CA -0.350 3.810
|
|---|
| 9825 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 CL 1S9J.pdbqt #1/A LYS 192 NZ -0.352 3.857
|
|---|
| 9826 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A LEU 197 1HD2 -0.353 2.963
|
|---|
| 9827 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A LEU 197 2HD2 -0.368 3.128
|
|---|
| 9828 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A SER 194 HB2 -0.376 3.136
|
|---|
| 9829 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 C 1S9J.pdbqt #1/A LEU 197 2HD2 -0.385 3.145
|
|---|
| 9830 | 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 O 1S9J.pdbqt #1/A VAL 82 1HG2 -0.389 2.849
|
|---|
| 9831 |
|
|---|
| 9832 |
|
|---|
| 9833 |
|
|---|
| 9834 | 47 contacts
|
|---|
| 9835 |
|
|---|
| 9836 | > hbonds :UNL showDist true radius 0.05 log true saveFile
|
|---|
| 9837 | > /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1S9J--
|
|---|
| 9838 | > WRM-16.hbonds.txt
|
|---|
| 9839 |
|
|---|
| 9840 |
|
|---|
| 9841 | Finding intermodel H-bonds
|
|---|
| 9842 | Finding intramodel H-bonds
|
|---|
| 9843 | Constraints relaxed by 0.4 angstroms and 20 degrees
|
|---|
| 9844 | Models used:
|
|---|
| 9845 | 1 1S9J.pdbqt
|
|---|
| 9846 | 2.1 1S9J--WRM-16.result.pdbqt
|
|---|
| 9847 |
|
|---|
| 9848 | 1 H-bonds
|
|---|
| 9849 | H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
|
|---|
| 9850 | 1S9J.pdbqt #1/A LYS 97 NZ 1S9J--WRM-16.result.pdbqt #2.1/? UNL 1 O 1S9J.pdbqt #1/A LYS 97 HZ1 3.189 2.451
|
|---|
| 9851 |
|
|---|
| 9852 |
|
|---|
| 9853 |
|
|---|
| 9854 | 1 hydrogen bonds found
|
|---|
| 9855 |
|
|---|
| 9856 | > select :UNL
|
|---|
| 9857 |
|
|---|
| 9858 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 9859 |
|
|---|
| 9860 | > label sel text "Ligand "
|
|---|
| 9861 |
|
|---|
| 9862 | > label height 1
|
|---|
| 9863 |
|
|---|
| 9864 | > ~select
|
|---|
| 9865 |
|
|---|
| 9866 | Nothing selected
|
|---|
| 9867 |
|
|---|
| 9868 | > 2dlabels text "Binding Energy: -9.2 kcal/mol" color red size 18 xpos .03
|
|---|
| 9869 | > ypos .95
|
|---|
| 9870 |
|
|---|
| 9871 | > 2dlabels text "1S9J WRM-16 Complex" color gray size 18 xpos .03 ypos .91
|
|---|
| 9872 |
|
|---|
| 9873 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1S9J--
|
|---|
| 9874 | > WRM-16.complex.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 9875 | > true
|
|---|
| 9876 |
|
|---|
| 9877 | > select :UNL
|
|---|
| 9878 |
|
|---|
| 9879 | 28 atoms, 31 bonds, 1 residue, 1 model selected
|
|---|
| 9880 |
|
|---|
| 9881 | > view sel
|
|---|
| 9882 |
|
|---|
| 9883 | > save /home/vishalkumarsahu/Desktop/DGE8-2-Docking/analysis/1S9J--
|
|---|
| 9884 | > WRM-16.ligand.png width 1200 height 838 supersample 4 transparentBackground
|
|---|
| 9885 | > true
|
|---|
| 9886 |
|
|---|
| 9887 | > close
|
|---|
| 9888 |
|
|---|
| 9889 | > wait 5
|
|---|
| 9890 |
|
|---|
| 9891 | > set bgColor white
|
|---|
| 9892 |
|
|---|
| 9893 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/1XJV.pdbqt
|
|---|
| 9894 |
|
|---|
| 9895 | Chain information for 1XJV.pdbqt #1
|
|---|
| 9896 | ---
|
|---|
| 9897 | Chain | Description
|
|---|
| 9898 | A | No description available
|
|---|
| 9899 | B | No description available
|
|---|
| 9900 |
|
|---|
| 9901 | Opened 1XJV.pdbqt containing 1 structures (4991 atoms, 5066 bonds)
|
|---|
| 9902 |
|
|---|
| 9903 | > wait 5
|
|---|
| 9904 |
|
|---|
| 9905 | > hide surfaces
|
|---|
| 9906 |
|
|---|
| 9907 | > hide atoms
|
|---|
| 9908 |
|
|---|
| 9909 | > show cartoons
|
|---|
| 9910 |
|
|---|
| 9911 | > wait 5
|
|---|
| 9912 |
|
|---|
| 9913 | > addh
|
|---|
| 9914 |
|
|---|
| 9915 | Summary of feedback from adding hydrogens to 1XJV.pdbqt #1
|
|---|
| 9916 | ---
|
|---|
| 9917 | notes | No usable SEQRES records for 1XJV.pdbqt (#1) chain A; guessing termini
|
|---|
| 9918 | instead
|
|---|
| 9919 | No usable SEQRES records for 1XJV.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 9920 | Chain-initial residues that are actual N termini: /A ALA 6, /B DT 1
|
|---|
| 9921 | Chain-initial residues that are not actual N termini: /A THR 149
|
|---|
| 9922 | Chain-final residues that are actual C termini: /A ALA 299, /B DG 10
|
|---|
| 9923 | Chain-final residues that are not actual C termini: /A SER 145
|
|---|
| 9924 | 244 hydrogen bonds
|
|---|
| 9925 |
|
|---|
| 9926 | Traceback (most recent call last):
|
|---|
| 9927 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 9928 | packages/chimerax/cmd_line/tool.py", line 280, in execute
|
|---|
| 9929 | cmd.run(cmd_text)
|
|---|
| 9930 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 9931 | packages/chimerax/core/commands/cli.py", line 2852, in run
|
|---|
| 9932 | result = ci.function(session, **kw_args)
|
|---|
| 9933 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 9934 | packages/chimerax/open_command/cmd.py", line 118, in cmd_open
|
|---|
| 9935 | models = Command(session, registry=registry).run(provider_cmd_text,
|
|---|
| 9936 | log=log)[0]
|
|---|
| 9937 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 9938 | packages/chimerax/core/commands/cli.py", line 2852, in run
|
|---|
| 9939 | result = ci.function(session, **kw_args)
|
|---|
| 9940 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 9941 | packages/chimerax/open_command/cmd.py", line 179, in provider_open
|
|---|
| 9942 | models, status = collated_open(session, None, [data], data_format,
|
|---|
| 9943 | _add_models,
|
|---|
| 9944 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 9945 | packages/chimerax/open_command/cmd.py", line 404, in collated_open
|
|---|
| 9946 | return func(*func_args, **func_kw)
|
|---|
| 9947 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 9948 | packages/chimerax/core_formats/__init__.py", line 37, in open
|
|---|
| 9949 | return open_command_script(session, data, file_name)
|
|---|
| 9950 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 9951 | packages/chimerax/core/scripting.py", line 161, in open_command_script
|
|---|
| 9952 | run(session, text)
|
|---|
| 9953 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 9954 | packages/chimerax/core/commands/run.py", line 36, in run
|
|---|
| 9955 | results = command.run(text, log=log, return_json=return_json)
|
|---|
| 9956 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 9957 | packages/chimerax/core/commands/cli.py", line 2852, in run
|
|---|
| 9958 | result = ci.function(session, **kw_args)
|
|---|
| 9959 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 9960 | packages/chimerax/addh/cmd.py", line 63, in cmd_addh
|
|---|
| 9961 | add_h_func(session, structures, template=template, in_isolation=in_isolation,
|
|---|
| 9962 | **prot_schemes)
|
|---|
| 9963 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 9964 | packages/chimerax/addh/cmd.py", line 170, in hbond_add_hydrogens
|
|---|
| 9965 | add_hydrogens(session, atoms, type_info_for_atom, naming_schemas,
|
|---|
| 9966 | hydrogen_totals,
|
|---|
| 9967 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 9968 | packages/chimerax/addh/hbond.py", line 447, in add_hydrogens
|
|---|
| 9969 | did_finish = _try_finish(end, hbond_info, finished, aro_amines, pruned_by,
|
|---|
| 9970 | processed)
|
|---|
| 9971 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 9972 | packages/chimerax/addh/hbond.py", line 1098, in _try_finish
|
|---|
| 9973 | pos = at_pos + nearest * h_len
|
|---|
| 9974 | TypeError: unsupported operand type(s) for *: 'NoneType' and 'float'
|
|---|
| 9975 |
|
|---|
| 9976 | TypeError: unsupported operand type(s) for *: 'NoneType' and 'float'
|
|---|
| 9977 |
|
|---|
| 9978 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 9979 | packages/chimerax/addh/hbond.py", line 1098, in _try_finish
|
|---|
| 9980 | pos = at_pos + nearest * h_len
|
|---|
| 9981 |
|
|---|
| 9982 | See log for complete Python traceback.
|
|---|
| 9983 |
|
|---|
| 9984 |
|
|---|
| 9985 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/ucsf-commands.cxc
|
|---|
| 9986 |
|
|---|
| 9987 | > set bgColor white
|
|---|
| 9988 |
|
|---|
| 9989 | > open /home/vishalkumarsahu/Desktop/DGE8-2-Docking/proteins-pdbqt/3EI4.pdbqt
|
|---|
| 9990 |
|
|---|
| 9991 | Chain information for 3EI4.pdbqt #2
|
|---|
| 9992 | ---
|
|---|
| 9993 | Chain | Description
|
|---|
| 9994 | A C E | No description available
|
|---|
| 9995 | B D F | No description available
|
|---|
| 9996 |
|
|---|
| 9997 | Opened 3EI4.pdbqt containing 1 structures (70284 atoms, 71031 bonds)
|
|---|
| 9998 |
|
|---|
| 9999 | > wait 5
|
|---|
| 10000 |
|
|---|
| 10001 | > hide surfaces
|
|---|
| 10002 |
|
|---|
| 10003 | > hide atoms
|
|---|
| 10004 |
|
|---|
| 10005 | > show cartoons
|
|---|
| 10006 |
|
|---|
| 10007 | > wait 5
|
|---|
| 10008 |
|
|---|
| 10009 | > addh
|
|---|
| 10010 |
|
|---|
| 10011 | Summary of feedback from adding hydrogens to multiple structures
|
|---|
| 10012 | ---
|
|---|
| 10013 | notes | No usable SEQRES records for 1XJV.pdbqt (#1) chain A; guessing termini
|
|---|
| 10014 | instead
|
|---|
| 10015 | No usable SEQRES records for 1XJV.pdbqt (#1) chain B; guessing termini instead
|
|---|
| 10016 | Chain-initial residues that are actual N termini: 1XJV.pdbqt #1/A ALA 6,
|
|---|
| 10017 | 1XJV.pdbqt #1/B DT 1
|
|---|
| 10018 | Chain-initial residues that are not actual N termini: 1XJV.pdbqt #1/A THR 149
|
|---|
| 10019 | Chain-final residues that are actual C termini: 1XJV.pdbqt #1/A ALA 299,
|
|---|
| 10020 | 1XJV.pdbqt #1/B DG 10
|
|---|
| 10021 | Chain-final residues that are not actual C termini: 1XJV.pdbqt #1/A SER 145
|
|---|
| 10022 | 244 hydrogen bonds
|
|---|
| 10023 |
|
|---|
| 10024 | Traceback (most recent call last):
|
|---|
| 10025 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10026 | packages/chimerax/cmd_line/tool.py", line 280, in execute
|
|---|
| 10027 | cmd.run(cmd_text)
|
|---|
| 10028 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10029 | packages/chimerax/core/commands/cli.py", line 2852, in run
|
|---|
| 10030 | result = ci.function(session, **kw_args)
|
|---|
| 10031 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10032 | packages/chimerax/open_command/cmd.py", line 118, in cmd_open
|
|---|
| 10033 | models = Command(session, registry=registry).run(provider_cmd_text,
|
|---|
| 10034 | log=log)[0]
|
|---|
| 10035 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10036 | packages/chimerax/core/commands/cli.py", line 2852, in run
|
|---|
| 10037 | result = ci.function(session, **kw_args)
|
|---|
| 10038 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10039 | packages/chimerax/open_command/cmd.py", line 179, in provider_open
|
|---|
| 10040 | models, status = collated_open(session, None, [data], data_format,
|
|---|
| 10041 | _add_models,
|
|---|
| 10042 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10043 | packages/chimerax/open_command/cmd.py", line 404, in collated_open
|
|---|
| 10044 | return func(*func_args, **func_kw)
|
|---|
| 10045 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10046 | packages/chimerax/core_formats/__init__.py", line 37, in open
|
|---|
| 10047 | return open_command_script(session, data, file_name)
|
|---|
| 10048 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10049 | packages/chimerax/core/scripting.py", line 161, in open_command_script
|
|---|
| 10050 | run(session, text)
|
|---|
| 10051 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10052 | packages/chimerax/core/commands/run.py", line 36, in run
|
|---|
| 10053 | results = command.run(text, log=log, return_json=return_json)
|
|---|
| 10054 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10055 | packages/chimerax/core/commands/cli.py", line 2852, in run
|
|---|
| 10056 | result = ci.function(session, **kw_args)
|
|---|
| 10057 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10058 | packages/chimerax/addh/cmd.py", line 63, in cmd_addh
|
|---|
| 10059 | add_h_func(session, structures, template=template, in_isolation=in_isolation,
|
|---|
| 10060 | **prot_schemes)
|
|---|
| 10061 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10062 | packages/chimerax/addh/cmd.py", line 162, in hbond_add_hydrogens
|
|---|
| 10063 | hbond_add_hydrogens(session, [struct], unknowns_info=unknowns_info,
|
|---|
| 10064 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10065 | packages/chimerax/addh/cmd.py", line 170, in hbond_add_hydrogens
|
|---|
| 10066 | add_hydrogens(session, atoms, type_info_for_atom, naming_schemas,
|
|---|
| 10067 | hydrogen_totals,
|
|---|
| 10068 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10069 | packages/chimerax/addh/hbond.py", line 447, in add_hydrogens
|
|---|
| 10070 | did_finish = _try_finish(end, hbond_info, finished, aro_amines, pruned_by,
|
|---|
| 10071 | processed)
|
|---|
| 10072 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10073 | packages/chimerax/addh/hbond.py", line 1098, in _try_finish
|
|---|
| 10074 | pos = at_pos + nearest * h_len
|
|---|
| 10075 | TypeError: unsupported operand type(s) for *: 'NoneType' and 'float'
|
|---|
| 10076 |
|
|---|
| 10077 | TypeError: unsupported operand type(s) for *: 'NoneType' and 'float'
|
|---|
| 10078 |
|
|---|
| 10079 | File "/usr/lib/ucsf-chimerax/lib/python3.8/site-
|
|---|
| 10080 | packages/chimerax/addh/hbond.py", line 1098, in _try_finish
|
|---|
| 10081 | pos = at_pos + nearest * h_len
|
|---|
| 10082 |
|
|---|
| 10083 | See log for complete Python traceback.
|
|---|
| 10084 |
|
|---|
| 10085 |
|
|---|
| 10086 |
|
|---|
| 10087 |
|
|---|
| 10088 |
|
|---|
| 10089 | OpenGL version: 4.6 (Core Profile) Mesa 20.2.6
|
|---|
| 10090 | OpenGL renderer: Mesa Intel(R) UHD Graphics 630 (CFL GT2)
|
|---|
| 10091 | OpenGL vendor: Intel
|
|---|
| 10092 | Manufacturer: HP
|
|---|
| 10093 | Model: HP Desktop Pro G1 MT
|
|---|
| 10094 | OS: Ubuntu 20.04 focal
|
|---|
| 10095 | Architecture: 64bit ELF
|
|---|
| 10096 | Virutal Machine: none
|
|---|
| 10097 | CPU: 6 Intel(R) Core(TM) i5-8500 CPU @ 3.00GHz
|
|---|
| 10098 | Cache Size: 9216 KB
|
|---|
| 10099 | Memory:
|
|---|
| 10100 | total used free shared buff/cache available
|
|---|
| 10101 | Mem: 11Gi 5.2Gi 2.7Gi 401Mi 3.7Gi 5.7Gi
|
|---|
| 10102 | Swap: 31Gi 5.2Gi 26Gi
|
|---|
| 10103 |
|
|---|
| 10104 | Graphics:
|
|---|
| 10105 | 00:02.0 VGA compatible controller [0300]: Intel Corporation UHD Graphics 630 (Desktop) [8086:3e92]
|
|---|
| 10106 | DeviceName: Onboard - Video
|
|---|
| 10107 | Subsystem: Hewlett-Packard Company UHD Graphics 630 (Desktop) [103c:843c]
|
|---|
| 10108 | Locale: ('en_IN', 'ISO8859-1')
|
|---|
| 10109 | PyQt5 5.15.2, Qt 5.15.2
|
|---|
| 10110 | Installed Packages:
|
|---|
| 10111 | alabaster: 0.7.12
|
|---|
| 10112 | appdirs: 1.4.4
|
|---|
| 10113 | Babel: 2.9.1
|
|---|
| 10114 | backcall: 0.2.0
|
|---|
| 10115 | blockdiag: 2.0.1
|
|---|
| 10116 | certifi: 2020.12.5
|
|---|
| 10117 | cftime: 1.5.0
|
|---|
| 10118 | chardet: 3.0.4
|
|---|
| 10119 | ChimeraX-AddCharge: 1.0.1
|
|---|
| 10120 | ChimeraX-AddH: 2.1.6
|
|---|
| 10121 | ChimeraX-AlignmentAlgorithms: 2.0
|
|---|
| 10122 | ChimeraX-AlignmentHdrs: 3.2
|
|---|
| 10123 | ChimeraX-AlignmentMatrices: 2.0
|
|---|
| 10124 | ChimeraX-Alignments: 2.1
|
|---|
| 10125 | ChimeraX-AmberInfo: 1.0
|
|---|
| 10126 | ChimeraX-Arrays: 1.0
|
|---|
| 10127 | ChimeraX-Atomic: 1.13.2
|
|---|
| 10128 | ChimeraX-AtomicLibrary: 3.1.3
|
|---|
| 10129 | ChimeraX-AtomSearch: 2.0
|
|---|
| 10130 | ChimeraX-AtomSearchLibrary: 1.0
|
|---|
| 10131 | ChimeraX-AxesPlanes: 2.0
|
|---|
| 10132 | ChimeraX-BasicActions: 1.1
|
|---|
| 10133 | ChimeraX-BILD: 1.0
|
|---|
| 10134 | ChimeraX-BlastProtein: 1.1
|
|---|
| 10135 | ChimeraX-BondRot: 2.0
|
|---|
| 10136 | ChimeraX-BugReporter: 1.0
|
|---|
| 10137 | ChimeraX-BuildStructure: 2.5.2
|
|---|
| 10138 | ChimeraX-Bumps: 1.0
|
|---|
| 10139 | ChimeraX-BundleBuilder: 1.1
|
|---|
| 10140 | ChimeraX-ButtonPanel: 1.0
|
|---|
| 10141 | ChimeraX-CageBuilder: 1.0
|
|---|
| 10142 | ChimeraX-CellPack: 1.0
|
|---|
| 10143 | ChimeraX-Centroids: 1.1
|
|---|
| 10144 | ChimeraX-ChemGroup: 2.0
|
|---|
| 10145 | ChimeraX-Clashes: 2.1
|
|---|
| 10146 | ChimeraX-ColorActions: 1.0
|
|---|
| 10147 | ChimeraX-ColorGlobe: 1.0
|
|---|
| 10148 | ChimeraX-ColorKey: 1.2.1
|
|---|
| 10149 | ChimeraX-CommandLine: 1.1.4
|
|---|
| 10150 | ChimeraX-ConnectStructure: 2.0
|
|---|
| 10151 | ChimeraX-Contacts: 1.0
|
|---|
| 10152 | ChimeraX-Core: 1.2.5
|
|---|
| 10153 | ChimeraX-CoreFormats: 1.0
|
|---|
| 10154 | ChimeraX-coulombic: 1.1.1
|
|---|
| 10155 | ChimeraX-Crosslinks: 1.0
|
|---|
| 10156 | ChimeraX-Crystal: 1.0
|
|---|
| 10157 | ChimeraX-CrystalContacts: 1.0
|
|---|
| 10158 | ChimeraX-DataFormats: 1.1
|
|---|
| 10159 | ChimeraX-Dicom: 1.0
|
|---|
| 10160 | ChimeraX-DistMonitor: 1.1.3
|
|---|
| 10161 | ChimeraX-DistUI: 1.0
|
|---|
| 10162 | ChimeraX-Dssp: 2.0
|
|---|
| 10163 | ChimeraX-EMDB-SFF: 1.0
|
|---|
| 10164 | ChimeraX-ExperimentalCommands: 1.0
|
|---|
| 10165 | ChimeraX-FileHistory: 1.0
|
|---|
| 10166 | ChimeraX-FunctionKey: 1.0
|
|---|
| 10167 | ChimeraX-Geometry: 1.1
|
|---|
| 10168 | ChimeraX-gltf: 1.0
|
|---|
| 10169 | ChimeraX-Graphics: 1.0
|
|---|
| 10170 | ChimeraX-Hbonds: 2.1
|
|---|
| 10171 | ChimeraX-Help: 1.1
|
|---|
| 10172 | ChimeraX-HKCage: 1.3
|
|---|
| 10173 | ChimeraX-IHM: 1.0
|
|---|
| 10174 | ChimeraX-ImageFormats: 1.1
|
|---|
| 10175 | ChimeraX-IMOD: 1.0
|
|---|
| 10176 | ChimeraX-IO: 1.0.1
|
|---|
| 10177 | ChimeraX-Label: 1.0
|
|---|
| 10178 | ChimeraX-LinuxSupport: 1.0
|
|---|
| 10179 | ChimeraX-ListInfo: 1.1.1
|
|---|
| 10180 | ChimeraX-Log: 1.1.2
|
|---|
| 10181 | ChimeraX-LookingGlass: 1.1
|
|---|
| 10182 | ChimeraX-Maestro: 1.8.1
|
|---|
| 10183 | ChimeraX-Map: 1.0.2
|
|---|
| 10184 | ChimeraX-MapData: 2.0
|
|---|
| 10185 | ChimeraX-MapEraser: 1.0
|
|---|
| 10186 | ChimeraX-MapFilter: 2.0
|
|---|
| 10187 | ChimeraX-MapFit: 2.0
|
|---|
| 10188 | ChimeraX-MapSeries: 2.0
|
|---|
| 10189 | ChimeraX-Markers: 1.0
|
|---|
| 10190 | ChimeraX-Mask: 1.0
|
|---|
| 10191 | ChimeraX-MatchMaker: 1.2.1
|
|---|
| 10192 | ChimeraX-MDcrds: 2.2
|
|---|
| 10193 | ChimeraX-MedicalToolbar: 1.0.1
|
|---|
| 10194 | ChimeraX-Meeting: 1.0
|
|---|
| 10195 | ChimeraX-MLP: 1.1
|
|---|
| 10196 | ChimeraX-mmCIF: 2.3
|
|---|
| 10197 | ChimeraX-MMTF: 2.1
|
|---|
| 10198 | ChimeraX-Modeller: 1.0.1
|
|---|
| 10199 | ChimeraX-ModelPanel: 1.0.1
|
|---|
| 10200 | ChimeraX-ModelSeries: 1.0
|
|---|
| 10201 | ChimeraX-Mol2: 2.0
|
|---|
| 10202 | ChimeraX-Morph: 1.0
|
|---|
| 10203 | ChimeraX-MouseModes: 1.1
|
|---|
| 10204 | ChimeraX-Movie: 1.0
|
|---|
| 10205 | ChimeraX-Neuron: 1.0
|
|---|
| 10206 | ChimeraX-Nucleotides: 2.0.1
|
|---|
| 10207 | ChimeraX-OpenCommand: 1.5
|
|---|
| 10208 | ChimeraX-PDB: 2.4.1
|
|---|
| 10209 | ChimeraX-PDBBio: 1.0
|
|---|
| 10210 | ChimeraX-PDBLibrary: 1.0.1
|
|---|
| 10211 | ChimeraX-PDBMatrices: 1.0
|
|---|
| 10212 | ChimeraX-PickBlobs: 1.0
|
|---|
| 10213 | ChimeraX-Positions: 1.0
|
|---|
| 10214 | ChimeraX-PresetMgr: 1.0.1
|
|---|
| 10215 | ChimeraX-PubChem: 2.0.1
|
|---|
| 10216 | ChimeraX-ReadPbonds: 1.0
|
|---|
| 10217 | ChimeraX-Registration: 1.1
|
|---|
| 10218 | ChimeraX-RemoteControl: 1.0
|
|---|
| 10219 | ChimeraX-ResidueFit: 1.0
|
|---|
| 10220 | ChimeraX-RestServer: 1.1
|
|---|
| 10221 | ChimeraX-RNALayout: 1.0
|
|---|
| 10222 | ChimeraX-RotamerLibMgr: 2.0
|
|---|
| 10223 | ChimeraX-RotamerLibsDunbrack: 2.0
|
|---|
| 10224 | ChimeraX-RotamerLibsDynameomics: 2.0
|
|---|
| 10225 | ChimeraX-RotamerLibsRichardson: 2.0
|
|---|
| 10226 | ChimeraX-SaveCommand: 1.4
|
|---|
| 10227 | ChimeraX-SchemeMgr: 1.0
|
|---|
| 10228 | ChimeraX-SDF: 2.0
|
|---|
| 10229 | ChimeraX-Segger: 1.0
|
|---|
| 10230 | ChimeraX-Segment: 1.0
|
|---|
| 10231 | ChimeraX-SeqView: 2.3
|
|---|
| 10232 | ChimeraX-Shape: 1.0.1
|
|---|
| 10233 | ChimeraX-Shell: 1.0
|
|---|
| 10234 | ChimeraX-Shortcuts: 1.0
|
|---|
| 10235 | ChimeraX-ShowAttr: 1.0
|
|---|
| 10236 | ChimeraX-ShowSequences: 1.0
|
|---|
| 10237 | ChimeraX-SideView: 1.0
|
|---|
| 10238 | ChimeraX-Smiles: 2.0.1
|
|---|
| 10239 | ChimeraX-SmoothLines: 1.0
|
|---|
| 10240 | ChimeraX-SpaceNavigator: 1.0
|
|---|
| 10241 | ChimeraX-StdCommands: 1.3.1
|
|---|
| 10242 | ChimeraX-STL: 1.0
|
|---|
| 10243 | ChimeraX-Storm: 1.0
|
|---|
| 10244 | ChimeraX-Struts: 1.0
|
|---|
| 10245 | ChimeraX-Surface: 1.0
|
|---|
| 10246 | ChimeraX-SwapAA: 2.0
|
|---|
| 10247 | ChimeraX-SwapRes: 2.1
|
|---|
| 10248 | ChimeraX-TapeMeasure: 1.0
|
|---|
| 10249 | ChimeraX-Test: 1.0
|
|---|
| 10250 | ChimeraX-Toolbar: 1.0.1
|
|---|
| 10251 | ChimeraX-ToolshedUtils: 1.2
|
|---|
| 10252 | ChimeraX-Tug: 1.0
|
|---|
| 10253 | ChimeraX-UI: 1.7.6
|
|---|
| 10254 | ChimeraX-uniprot: 2.1
|
|---|
| 10255 | ChimeraX-UnitCell: 1.0
|
|---|
| 10256 | ChimeraX-ViewDockX: 1.0
|
|---|
| 10257 | ChimeraX-Vive: 1.1
|
|---|
| 10258 | ChimeraX-VolumeMenu: 1.0
|
|---|
| 10259 | ChimeraX-VTK: 1.0
|
|---|
| 10260 | ChimeraX-WavefrontOBJ: 1.0
|
|---|
| 10261 | ChimeraX-WebCam: 1.0
|
|---|
| 10262 | ChimeraX-WebServices: 1.0
|
|---|
| 10263 | ChimeraX-Zone: 1.0
|
|---|
| 10264 | colorama: 0.4.3
|
|---|
| 10265 | comtypes: 1.1.7
|
|---|
| 10266 | cxservices: 1.0
|
|---|
| 10267 | cycler: 0.10.0
|
|---|
| 10268 | Cython: 0.29.21
|
|---|
| 10269 | decorator: 5.0.9
|
|---|
| 10270 | distlib: 0.3.1
|
|---|
| 10271 | distro: 1.5.0
|
|---|
| 10272 | docutils: 0.16
|
|---|
| 10273 | filelock: 3.0.12
|
|---|
| 10274 | funcparserlib: 0.3.6
|
|---|
| 10275 | grako: 3.16.5
|
|---|
| 10276 | h5py: 2.10.0
|
|---|
| 10277 | html2text: 2020.1.16
|
|---|
| 10278 | idna: 2.10
|
|---|
| 10279 | ihm: 0.17
|
|---|
| 10280 | imagecodecs: 2020.5.30
|
|---|
| 10281 | imagesize: 1.2.0
|
|---|
| 10282 | ipykernel: 5.3.4
|
|---|
| 10283 | ipython: 7.18.1
|
|---|
| 10284 | ipython-genutils: 0.2.0
|
|---|
| 10285 | jedi: 0.17.2
|
|---|
| 10286 | Jinja2: 2.11.2
|
|---|
| 10287 | jupyter-client: 6.1.7
|
|---|
| 10288 | jupyter-core: 4.7.1
|
|---|
| 10289 | kiwisolver: 1.3.1
|
|---|
| 10290 | line-profiler: 2.1.2
|
|---|
| 10291 | lxml: 4.6.2
|
|---|
| 10292 | lz4: 3.1.0
|
|---|
| 10293 | MarkupSafe: 2.0.1
|
|---|
| 10294 | matplotlib: 3.3.2
|
|---|
| 10295 | msgpack: 1.0.0
|
|---|
| 10296 | netCDF4: 1.5.4
|
|---|
| 10297 | networkx: 2.5
|
|---|
| 10298 | numexpr: 2.7.3
|
|---|
| 10299 | numpy: 1.19.2
|
|---|
| 10300 | numpydoc: 1.1.0
|
|---|
| 10301 | openvr: 1.14.1501
|
|---|
| 10302 | packaging: 20.9
|
|---|
| 10303 | ParmEd: 3.2.0
|
|---|
| 10304 | parso: 0.7.1
|
|---|
| 10305 | pexpect: 4.8.0
|
|---|
| 10306 | pickleshare: 0.7.5
|
|---|
| 10307 | Pillow: 7.2.0
|
|---|
| 10308 | pip: 21.0.1
|
|---|
| 10309 | pkginfo: 1.5.0.1
|
|---|
| 10310 | prompt-toolkit: 3.0.18
|
|---|
| 10311 | psutil: 5.7.2
|
|---|
| 10312 | ptyprocess: 0.7.0
|
|---|
| 10313 | pycollada: 0.7.1
|
|---|
| 10314 | pydicom: 2.0.0
|
|---|
| 10315 | Pygments: 2.7.1
|
|---|
| 10316 | PyOpenGL: 3.1.5
|
|---|
| 10317 | PyOpenGL-accelerate: 3.1.5
|
|---|
| 10318 | pyparsing: 2.4.7
|
|---|
| 10319 | PyQt5-commercial: 5.15.2
|
|---|
| 10320 | PyQt5-sip: 12.8.1
|
|---|
| 10321 | PyQtWebEngine-commercial: 5.15.2
|
|---|
| 10322 | python-dateutil: 2.8.1
|
|---|
| 10323 | pytz: 2021.1
|
|---|
| 10324 | pyzmq: 22.0.3
|
|---|
| 10325 | qtconsole: 4.7.7
|
|---|
| 10326 | QtPy: 1.9.0
|
|---|
| 10327 | RandomWords: 0.3.0
|
|---|
| 10328 | requests: 2.24.0
|
|---|
| 10329 | scipy: 1.5.2
|
|---|
| 10330 | setuptools: 50.3.2
|
|---|
| 10331 | sfftk-rw: 0.6.7.dev1
|
|---|
| 10332 | six: 1.15.0
|
|---|
| 10333 | snowballstemmer: 2.1.0
|
|---|
| 10334 | sortedcontainers: 2.2.2
|
|---|
| 10335 | Sphinx: 3.2.1
|
|---|
| 10336 | sphinxcontrib-applehelp: 1.0.2
|
|---|
| 10337 | sphinxcontrib-blockdiag: 2.0.0
|
|---|
| 10338 | sphinxcontrib-devhelp: 1.0.2
|
|---|
| 10339 | sphinxcontrib-htmlhelp: 2.0.0
|
|---|
| 10340 | sphinxcontrib-jsmath: 1.0.1
|
|---|
| 10341 | sphinxcontrib-qthelp: 1.0.3
|
|---|
| 10342 | sphinxcontrib-serializinghtml: 1.1.5
|
|---|
| 10343 | suds-jurko: 0.6
|
|---|
| 10344 | tables: 3.6.1
|
|---|
| 10345 | tifffile: 2020.9.3
|
|---|
| 10346 | tinyarray: 1.2.3
|
|---|
| 10347 | tornado: 6.1
|
|---|
| 10348 | traitlets: 5.0.5
|
|---|
| 10349 | urllib3: 1.25.11
|
|---|
| 10350 | wcwidth: 0.2.5
|
|---|
| 10351 | webcolors: 1.11.1
|
|---|
| 10352 | wheel: 0.36.0
|
|---|
| 10353 | wheel-filename: 1.2.0
|
|---|
| 10354 |
|
|---|
| 10355 | }}}
|
|---|