[Chimera-users] How can I can calculate or know Gibbs free energy from UCSF Chimera

[Awah.Chidiebere.U at mh-hannover.de]

Dear Colleagues,

 

 

Thanks for developing such wonderful tools as Chimera for molecular
dynamics analysis of structure.

Please I have two questions:

 

1.       Is it possible to calculate Gibbs free energy  from complexes
on UCSF Chimera,  for examples when  complexes are solvated?

2.       On building structures , is it possible to simulate how a given
complex could bind DNA oligos , for example  when one makes  changes in
single nucleotides and ask  a given  DNA binding TF structure to bind it
on Chimera?

 

 

 

I would look forward to your response to these questions. I would also
be very happy if I could speak by phone with the administrators.

 

 

 

 

Thanks.

 

Best wishes,

 

Chidiebere U Awah MD Msc

PhD student , Molecular Medicine

Hannover Medical School , Germany.

-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://plato.cgl.ucsf.edu/pipermail/chimera-users/attachments/20150827/a991beb2/attachment.html>