[Chimera-users] Dimer construction from a monomer generated using Modeller

akshita kumar akki13 at gmail.com
Fri Mar 19 03:33:16 PDT 2010


Dear Members,

Using 1T3D as template, we have generated a homology model via Modeller. As
the biological unit is a trimeric structure we need to generate trimer of
the model too. Therefore we undertook structural alignment of the model and
individual template 1T3D chains ("a, b , c"). However in our model the loop
region that falls at the interface between two dimers is much  longer and as
a result the loops between dimer overlap each other.

Can anybody please suggest a solution for generating a dimer/trimer from the
monomer built using homology modelling.

Thanks
Akshita
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