<div>Dear Members,</div><div><br></div>Using 1T3D as template, we have generated a homology model via Modeller. As the biological unit is a trimeric structure we need to generate trimer of the model too. Therefore we undertook structural alignment of the model and individual template 1T3D chains ("a, b , c"). However in our model the loop region that falls at the interface between two dimers is much longer and as a result the loops between dimer overlap each other.<div>
<div><br></div><div>Can anybody please suggest a solution for generating a dimer/trimer from the monomer built using homology modelling. </div><div><br></div><div>Thanks</div><div>Akshita</div><div><br></div><div><br></div>
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