Structural basis of omega-3 fatty acid transport across the blood-brain barrier. Cater RJ, Chua GL et al. Nature. 2021 Jul 8;595(7866):315-319.
PspA adopts an ESCRT-III-like fold and remodels bacterial membranes. Junglas B, Huber ST et al. Cell. 2021 Jul 8;184(14):3674-3688.e18.
Cryo-electron tomography provides topological insights into mutant huntingtin exon 1 and polyQ aggregates. Galaz-Montoya JG, Shahmoradian SH et al. Commun Biol. 2021 Jul 8;4(1):849.
High-resolution crystal structures of transient intermediates in the phytochrome photocycle. Carrillo M, Pandey S et al. Structure. 2021 Jul 1;29(7):743-754.e4.
Mapping protein-protein interactions in homodimeric CYP102A1 by crosslinking and mass spectrometry. Felker D, Zhang H et al. Biophys Chem. 2021 Jul;274:106590.(Previously featured citations...)
Chimera SearchGoogle Search
May 6, 2021
We're looking for somebody to join the ChimeraX development team! Please see the job posting for details.
December 18, 2020
December 11, 2020
UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.
We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features. ChimeraX includes a significant subset of Chimera features (with more to come, see the missing features list) and is under active development. Users may choose to use both programs, and it is fine to have both installed.
Chimera is no longer under active development, and is only updated for critical maintenance. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.
Different conformations and even different proteins can be compared by morphing from one structure to another. Users can specify the method of coordinate interpolation and how many intermediate structures should be generated. The result is displayed in Chimera's trajectory viewer, MD Movie. The morph can then be saved in coordinate form or recorded as an animation. See also: Animation Gallery(More features...)
Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.
See also the RBVI holiday card gallery.
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