[Chimera-users] Mutagenesis

Elaine Meng meng at cgl.ucsf.edu
Wed Sep 22 10:46:59 PDT 2010


Hi R,
Amino acids can be mutated with command "swapaa" or the Rotamers graphical interface (allows interactively choosing rotamers of the same or a different amino acid)
<http://www.cgl.ucsf.edu/chimera/docs/UsersGuide/midas/swapaa.html>
<http://www.cgl.ucsf.edu/chimera/docs/ContributedSoftware/rotamers/rotamers.html>

If you were searching the chimera-user at cgl.ucsf.edu archive, you could find a handful of relevant messages with "mutation":
<http://plato.cgl.ucsf.edu/cgi-bin/swish-chimera-users.cgi?sort=swishrank&query=mutation&submit=Search+chimera-users+archive>

If you were using the documentation search box, Rotamers and swapaa could be found with the term "mutated" but not mutation/mutagenesis.  There are various other routes through the documentation, such as from the page on modifying data or the structure analysis and comparison tutorial.

Oh, and nucleic acids can be mutated with the command "swapna"
<http://www.cgl.ucsf.edu/chimera/docs/UsersGuide/midas/swapna.html>

Best,
Elaine
----------
Elaine C. Meng, Ph.D. 
UCSF Computer Graphics Lab (Chimera team) and Babbitt Lab
Department of Pharmaceutical Chemistry
University of California, San Francisco

On Sep 22, 2010, at 9:45 AM, r charbel maroun wrote:

> Dear Chimera users,
> 
> Please correct me if I'm wrong, but neither in Chimera nor in the user's list did I find any info on mutating a residue. Is this a missing functionality ?
> 
> Greetings





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