[[PageOutline]] == RBVI 2011 Renewal Ideas and Discussions == === Overview === === Technology Research and Development Projects === ==== TR&D !#1: Chimera Molecular Modeling Environment ==== * [wiki:Grant/chimeraplan Core 1 Chimera ideas] * [attachment:Chimera2011-outline.doc Core 1 outline] ==== TR&D !#2: Software for Interactive Analysis of Large Molecular Assemblies ==== * [attachment:core2_aims.txt Core 2 Specific Aims] * [wiki:Grant/emplan Core 2 early planning], EM and Molecular Assemblies, slides from December 3, 2010 planning meeting. * [attachment:core2-summary.pdf Core 2 summary] * [attachment:core2.docx Core 2 draft] * [attachment:core2.2.docx Core 2 draft with Scooter's modifications] ==== TR&D !#3: Structure-Function Linkage Database ==== * [wiki:Grant/Core3 Core 3 Specific Aims] ==== TR&D !#4: Integrated Analysis and Visualization of Biological Context ==== * [wiki:Grant/Core4 Core 4 Specific Aims] * [raw-attachment:Core4v2.docx Core 4 Draft] === Driving Biomedical Projects === * DBP !#1: Modeling Macromolecular Assemblies - Andrej Sali * DPB !#2: Enzyme Function Initiative - John Gerlt * DPB !#3: Parasitic Disease Pathways - Jim McKerrow * DPB !#4: HIV Accessory and Regulator Complexes - Nevan Krogan/Yifan Cheng * [attachment:DBP_Cheng.docx HARC cryoEM grant] from Yifan, 4 years old * DPB !#5: 3D Architecture of Hair Cell Stereocilia - Manfred Auer * [attachment:DBP_Auer.docx draft] from Manfred * DPB !#6: Modeling Biological Assemblies from cryoEM Maps - Wah Chiu * [attachment:DBP_Chiu.docx background material] from Wah * DPB !#7: Data Validation and Web Visualization at the EMDB and PDB - Berman/Lawson/Westbrook * [attachment:mapmodelVTFbullets.pdf EM validation task force summary] from Cathy Lawson * DPB !#8: Network Visualization of Genome Assembly Experiments - DeRisi * [raw-attachment:DBPTable.docx DBP Table] === Collaboration and Service === 1. Integrating Chimera into the NRAMM Automated Processing Pipeline * Investigators: Bridget Carragher and Clint Potter, Scripps Research Institute * Grant: NIH P41 RR017573 * [attachment:Collaboration_NRAMM.docx Write-up] from Clint Potter. 1. Molecular animations * Investigators: Graham Johnson 1. Protein Polymorphism * Investigators: Tom Alber and Paula Therese Lang, University of California, Berkeley 1. Pharmacogenetics of Membrane Transporters * Investigators: Kathleen Giacomini and Deanna Kroetz (UCSF) 1. Integration of Methods of Structural Analysis of Functional Site: Active Site Profiling * Investigator: Jacquelyn Fetrow, Wake Forrest University * Grant: 1. Images and Analysis for the Virus Particle Explorer Database * Investigator: Vijay Reddy, Scripps Research Institute * Grant: NIH P41 RR012255 * [attachment:Collaboration_Reddy.docx Chimera development ideas for ViPERdb] from Padmaja Natarajan 1. Shared postdoc – Project Title? * Investigators: Allan Kuckinsky, Agilent Foundation; Nevan Krogan, UCSF * Grant: Agilent (no grant number) 1. MMTK Integration with UCSF Chimera * Investigator: Jean-Didier Maréchal and Victor Munoz, Universitat Autònoma de Barcelona * Grant: 1. National Resource for Network Biology * Investigators: Trey Ideker, Gary Bader, Alex Pico, and Bruce Conklin * Grant: NIH P41 RR031228 * [raw-attachment:collab9.doc Collaboration #9] 1. Remote User Support and Bug Tracking * Investigators: * [raw-attachment:CollabTable.docx Collaboration and Service Table] === Training === === Appendix === * [wiki:Grant/appendix Items for inclusion on Appendix CD-ROM] === Documents === * [raw-attachment:renewalOverview.pdf Overview of P41 requirements and deliverables] * [raw-attachment:RBVIrenewal.pdf 2006 RBVI Grant] === Action items (partial list) === * Update these web pages: * www.cgl.ucsf.edu/Outreach/Dissemination/index.html