[[PageOutline]] == RBVI 2011 Renewal Ideas and Discussions == === Table of Contents === * [raw-attachment:fp3-TOC.docx Table of Contents] === Overview === * [raw-attachment:Overview.docx Research Plan overview] === Technology Research and Development Projects === ==== TR&D !#1: Chimera Molecular Modeling Environment ==== * [raw-attachment:TRD1.docx TR&D 1] ([raw-attachment:TRD1.pdf pdf]) ==== TR&D !#2: Software for Interactive Analysis of Large Molecular Assemblies ==== * [raw-attachment:TRD2.docx TR&D 2] ([raw-attachment:TRD2.pdf pdf]) ==== TR&D !#3: Structure-Function Linkage Database ==== * [raw-attachment:TRD3.docx TR&D 3] ([raw-attachment:TRD3.pdf pdf]) ==== TR&D !#4: Integrated Analysis and Visualization of Biological Context ==== * [raw-attachment:TRD4.docx TR&D 4] ([raw-attachment:TRD4.pdf pdf]) === Driving Biomedical Projects === * Do not edit any of the individual projects -- they have all been combined into a unified "DBP" section 1. DBP !#1: Modeling Macromolecular Assemblies - Andrej Sali * [raw-attachment:DBP1.docx DBP1] 1. DBP !#2: Enzyme Function Initiative - John Gerlt * [raw-attachment:DBP2.docx DBP2] 1. DBP !#3: Parasitic Disease Pathways - Jim McKerrow * [raw-attachment:DBP3.docx DBP3] 1. DBP !#4: HIV Accessory and Regulator Complexes - Nevan Krogan/Yifan Cheng * [raw-attachment:DBP4.docx DBP4] combined systems biology and cryoEM. * Original separate drafts [attachment:DBP_Cheng.docx cryoEM part] and [attachment:DBP4_Krogan.docx systems biology part]. 1. DBP !#5: 3D Architecture of Hair Cell Stereocilia - Manfred Auer * [raw-attachment:DBP5.docx DBP5] passed final review from Manfred. 1. DBP !#6: Modeling Biological Assemblies from cryoEM Maps - Wah Chiu * [raw-attachment:DBP6.docx DBP6 final version] 1. DBP !#7: Data Validation and Web Visualization at the EMDB and PDB - Berman/Chiu/Lawson/Westbrook/Dutta * [attachment:mapmodelVTFbullets.pdf EM validation task force summary] from Cathy Lawson * [raw-attachment:DBP7.docx DBP7 final version] 1. DBP !#8: Network Visualization of Genome Assembly Experiments - DeRisi * [raw-attachment:DBP8.docx DBP8] * [raw-attachment:combinedDBPs.docx Combined DBPs (except for summary table)] * [raw-attachment:combinedDBPs.pdf same in PDF format] * [raw-attachment:DBPTable.docx DBP Table] === Collaboration and Service === * Do not edit any of the individual projects -- they have all been combined into a unified "Collaborations" section 1. Integrating Chimera into the NRAMM Automated Processing Pipeline * Investigators: Bridget Carragher and Clint Potter, Scripps Research Institute * Grant: NIH P41 RR017573 * [attachment:Collaboration_NRAMM.docx Collaboration #1] from Clint Potter. 1. Molecular animations * Investigators: Graham Johnson * [attachment:collab-GTJ.docx Collaboration #2] 1. Protein Polymorphism * Investigators: Tom Alber and Paula Therese Lang, University of California, Berkeley * [attachment:collab-PTL.docx Collaboration #3] 1. Pharmacogenetics of Membrane Transporters * Investigators: Kathleen Giacomini and Deanna Kroetz (UCSF) * [attachment:collab-PMT.docx Collaboration #4] 1. Integration of Methods of Structural Analysis of Functional Site: Active Site Profiling * Investigator: Jacquelyn Fetrow, Wake Forrest University * Grant: * [raw-attachment:collab-JSF.docx Collaboration #5] 1. Images and Analysis for the Virus Particle Explorer Database * Investigator: Vijay Reddy, Scripps Research Institute * Grant: NIH P41 RR012255 * [attachment:Collaboration_Reddy.docx Collaboration #6] 1. Pipeline for Identifying Pathogen-Host Mechanisms via Systems Biology * Investigators: Allan Kuckinsky, Agilent Foundation; Nevan Krogan, UCSF * Grant: Agilent (no grant number) * [raw-attachment:collab7.docx Collaboration #7] 1. MMTK Integration with UCSF Chimera * Investigator: Jean-Didier Maréchal and Victor Munoz, Universitat Autònoma de Barcelona * Grant: Spanish Ministry of Science and Innovation, grants CSD2007-00006 and CTQ2008-06866-C02-01 * [attachment:collab-JDM.doc Collaboration #8] 1. National Resource for Network Biology * Investigators: Trey Ideker, Gary Bader, Alex Pico, and Bruce Conklin * Grant: NIH P41 RR031228 * [raw-attachment:collab9.doc Collaboration #9] 1. Visualization Vault, Web Services, and Remote User Support * Investigators: Ferrin and RBVI staff * [raw-attachment:collabService.doc Collaboration #10] * [raw-attachment:combinedCollabs.docx Complete Collaboration and Service section (except for summary table)] * [raw-attachment:combinedCollabs.pdf same in PDF format] * [raw-attachment:CollabTable.docx Collaboration and Service Table] === Training, Dissemination, Administration === * [raw-attachment:combinedTDA.docx Combined Training, Dissemination, and Administration (needs references section formatted)] === Letters of Support === * [raw-attachment:lettersIntro.docx Intro page for Letters section] * [raw-attachment:lettersCombined.pdf Combined letters file] === Appendix === * [wiki:Grant/appendix Items for inclusion on Appendix CD-ROM] === Documents === * [raw-attachment:renewalOverview.pdf Overview of P41 requirements and deliverables] * [raw-attachment:RBVIrenewal.pdf 2006 RBVI Grant] === Action items (partial list) === * Update these web pages: * www.cgl.ucsf.edu/Outreach/Dissemination/index.html