Changes between Initial Version and Version 1 of Grant/Core4


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Timestamp:
Mar 30, 2011, 9:41:21 AM (15 years ago)
Author:
Scooter Morris
Comment:

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  • Grant/Core4

    v1 v1  
     1= Core 4: Integrated Visualization and Analysis of Biological Context =
     2== Specific Aims ==
     3 * Specific Aim 1: Develop and deploy extensions to Cytoscape and Chimera that will support the integration of macromolecular structural visualization and analysis with network visualization and analysis.
     4 * Specific Aim 2: Develop and deploy tools to support the analysis of high-throughput data (genetic, mRNA expression, RNA-Seq, ChIP-Seq, Hi-C) in the context of biological pathways, protein-protein interaction networks, or other biological network representation.
     5  * Aim 2A: Extend existing clustering tools to support fuzzy clustering
     6  * Aim 2B: Support visualizations and analyses that allow comparisons between species, conditions, and time series data
     7  * Aim 2C: Investigate the potential value of a 3D visualization of Hi-C epigenetic data
     8 * Specific Aim 3: Support the investigation of protein function through the visualization and analysis of protein similarity networks.
     9  * Aim 3A: Extend and enhance Cytoscape plugin to improve usability and functionality.  Specifically, add support to allow end-users to visualize their proteins in the context of SFLD similarity networks.
     10  * Aim 3B: Support the interactive visualization of very large networks.
     11 * Specific Aim 4: Improve the overall Cytoscape user experience for RBVI collaborators and DBPs
     12  * Aim 4B: Improve grouping by visually identifying grouped nodes and allowing for progressive disclosure concepts with the Cytoscape core.
     13  * Aim 4C: Add new techniques for visually mapping data to network elements such as nodes and edges.