| | 1 | |
| | 2 | --------------------------------------------------------------------------- |
| | 3 | 2012/2013 report |
| | 4 | --------------------------------------------------------------------------- |
| | 5 | |
| | 6 | April 18, 2012 |
| | 7 | NASA AbSciCon meeting, Atlanta, GA. Presentation on enzyme evolution, networks, |
| | 8 | and the SFLD. 9 hours prep, 35 attendees. |
| | 9 | - Patsy Babbitt |
| | 10 | |
| | 11 | April 21, 2012 |
| | 12 | UCSF Alumni Homecoming Demonstrations. A series of 30 minute demonstrations were given |
| | 13 | to several groups (about 100 individuals overall) of UCSF alumni from the Schools of |
| | 14 | Medicine and Pharmacy, and the PhD programs. |
| | 15 | - Tom Ferrin |
| | 16 | |
| | 17 | April 23, 2012 |
| | 18 | Molecular visualization demonstration for 10 high school science teachers from the |
| | 19 | San Francisco Unified School District. |
| | 20 | - Tom Ferrin |
| | 21 | |
| | 22 | April 27, 2012 |
| | 23 | Full day Cytoscape workshop for 30 participants at the University of Missouri. |
| | 24 | - Scooter Morris |
| | 25 | |
| | 26 | April 28, 2012 |
| | 27 | 2 1/2 hour Chimera workshop for 25 participants at the University of Missouri. |
| | 28 | - Scooter Morris |
| | 29 | |
| | 30 | May 23, 2012 |
| | 31 | EFI Meeting, San Francisco. SFLD new progress and future plans. ~6 hours prep, |
| | 32 | 15 attendees. |
| | 33 | - Patsy Babbitt |
| | 34 | |
| | 35 | June 21, 2012 |
| | 36 | Lecture for UC systemwide Bioengineering Symposium, Berkeley, CA. |
| | 37 | Computational guidance for protein design, including superfamilies, networks, and |
| | 38 | use of the SFLD. 8 hours prep time, 35 attendees. |
| | 39 | - Patsy Babbitt |
| | 40 | |
| | 41 | June 22, 2012 |
| | 42 | Nanomachine and virus visualization demo for 11 [http://igem.ucsf.edu iGem] students ages 17-19. |
| | 43 | 30 minutes, stereo visualization in viz vault, discussion of differences between human |
| | 44 | designed and biological molecular machines. 1 hour preparation. Organized by Shannon |
| | 45 | Noonan, Community Outreach Specialist, Gladstone Institutes. |
| | 46 | - Tom Goddard |
| | 47 | |
| | 48 | June 22, 2012 |
| | 49 | HIV virus visualization demonstration for 7 high school students in the |
| | 50 | [http://www.gladstone.ucsf.edu/gladstone/site/cso/section/2461 Gladstone Summer Scholars (GSS) Internship Program]. |
| | 51 | Looked at electron microscopy and |
| | 52 | atomic models of virus core and drug binding. 30 minute demo in viz vault. |
| | 53 | 1 hour preparation. Organized by Shannon Noonan, Community Outreach Specialist, |
| | 54 | Gladstone Institutes. |
| | 55 | - Tom Goddard |
| | 56 | |
| | 57 | June 22, 2012 |
| | 58 | Nanomachine and virus visualization demo for 6 [http://momagic.org Mo Magic] high school |
| | 59 | students. |
| | 60 | 30 minutes, stereo visualization in viz vault, discussion of differences between human |
| | 61 | designed and biological molecular machines. 1 hour preparation. Sponsored by Patricia |
| | 62 | Caldera, UCSF, Science & Health Education Partnership. |
| | 63 | - Tom Goddard |
| | 64 | |
| | 65 | July 3, 2012 |
| | 66 | Chimera training (3-hr session) for 4 members of the DeGrado group at UCSF, covering |
| | 67 | fetching data, structural analysis and comparison, H-bonds, superposition, morphing, |
| | 68 | attributes, working with sequences, density display, making movies; Q & A. 20 hours prep. |
| | 69 | - Elaine Meng, Eric Pettersen, Tom Ferrin |
| | 70 | |
| | 71 | July 11, 2012 |
| | 72 | Hands-on Chimera tutorials for 50 participants at the National University of Singapore |
| | 73 | [http://ncmi.bcm.edu/ncmi/events/workshops/workshops_125 cryoEM workshop]. |
| | 74 | [http://www.cgl.ucsf.edu/chimera/data/singapore-jul2012/nus.html Tutorials] covering |
| | 75 | electron tomography segmentation, molecule display, and fitting as well as an open |
| | 76 | question and answer session totaling 3 hours were |
| | 77 | presented via teleconference using WebEx with participants trying what they were shown |
| | 78 | on lab computers. Hosted by Cynthia He and Wah Chiu. 15 hours preparation. |
| | 79 | - Tom Goddard |
| | 80 | |
| | 81 | July 16, 2012 |
| | 82 | 5th International Conference on Paraoxonases, Columbus, OH. Presented research on the |
| | 83 | "nucleophilic attack 6-bladed beta-propeller" (N6P) superfamily, including network |
| | 84 | analysis and data dissemination using the SFLD. 12 hours prep time, 120 attendees. |
| | 85 | - Patsy Babbitt |
| | 86 | |
| | 87 | July 26, 2012 |
| | 88 | Chimera visualization of HIV virus core and drug binding for 20 high school students from the UC Davis |
| | 89 | [http://cosmos.ucdavis.edu COSMOS program]. Organized by Sarah Driver from UC Davis. 20 minute demo. |
| | 90 | 1 hour preparation. |
| | 91 | - Tom Goddard, Tom Ferrin, Scooter Morris |
| | 92 | |
| | 93 | August 14, 2012 |
| | 94 | Chimera visualization demonstration covering protein structures and sequences (dipeptide epimerase) |
| | 95 | and multiple length scales, atoms through cells (T-cell tomography and termite gut EM). 90 minutes. |
| | 96 | 12 first year graduate students in structural and computational biology, Baylor College of Medicine. |
| | 97 | Presented via WebEx screen sharing. Hosted by Wah Chiu. 6 hours preparation. |
| | 98 | - Tom Goddard |
| | 99 | |
| | 100 | August 27, 2012 |
| | 101 | [http://www.cgl.ucsf.edu/chimera/data/santa-cruz-aug2012/animate.html Movie making demonstration] |
| | 102 | showing how to morph electron microscopy maps and molecular structures fit into maps using Chimera. |
| | 103 | Used actin-like ParM filament data. Presented to 60 people at the Bay Area cryoEM meeting at Santa Cruz. |
| | 104 | Hosted by Melissa Jurica. 8 hours preparation. |
| | 105 | - Tom Goddard |
| | 106 | |
| | 107 | September 29, 2012 |
| | 108 | Workshop on the Radical SAM Superfamily (data in SFLD) at UCSF, full-day meeting with experts. Estimated 8 hours talk preparation, 30 attendees. |
| | 109 | - Gemma Holliday |
| | 110 | |
| | 111 | October 2-3, 2012 |
| | 112 | Chimera workshop at NIH, Bethesda MD. Eight sessions over two days, including |
| | 113 | introduction to Chimera, structure analysis, sequence-structure tools, EM density analysis, |
| | 114 | publication images and movies. About 30 attendees, the room capacity. About 20 more participants |
| | 115 | off-site with video and audio using Adobe Connect. 150 hours preparation. |
| | 116 | [http://www.cgl.ucsf.edu/Outreach/Workshops/NIH-Oct-2012/ workshop materials] |
| | 117 | - Tom Ferrin, Scooter Morris, Tom Goddard, Conrad Huang, Eric Pettersen, Elaine Meng |
| | 118 | |
| | 119 | October 4, 2012 |
| | 120 | Full-day Cytoscape workshop at NIH, Bethesda MD. Network visualization and analysis with Cytoscape. |
| | 121 | About 30 attendees, the room capacity. About 10 more participants |
| | 122 | off-site with video and audio using Adobe Connect. |
| | 123 | [http://www.cgl.ucsf.edu/Outreach/Workshops/NIH-Oct-2012/ workshop materials] |
| | 124 | - Scooter Morris, Elaine Meng |
| | 125 | |
| | 126 | October 4-5, 2012 |
| | 127 | Visits to NIH labs (Sriram Subramaniam, John Patton, Bernard Heymann, BK Lee, and others) for Chimera |
| | 128 | training using their data sets. Two days with RBVI staff divided into groups to help different labs. |
| | 129 | Topics included Chimera Python programming, HIV virus spikes, annotating FIBSEM imaging data, rotavirus |
| | 130 | RNA structures, hybrid model representations, and many others. |
| | 131 | - Tom Ferrin, Scooter Morris, Tom Goddard, Conrad Huang, Eric Pettersen, Elaine Meng |
| | 132 | |
| | 133 | October 14-30, 2012 |
| | 134 | 4 hours lecture in BMI206, Introduction to Bioinformatics (UCSF), featuring superfamily analysis, |
| | 135 | protein similarity networks, and the SFLD. The SFLD was also used as a primary data resource for |
| | 136 | a course lab assignment. 25 hours prep, ~9 attendees. |
| | 137 | - Patsy Babbitt |
| | 138 | |
| | 139 | October 17, 2012 |
| | 140 | UCSF BP204,"Macromolecular Interactions" class: 35-minute presentation followed by 45 mins of the |
| | 141 | students (about 25 of them) doing a Chimera tutorial on their own laptops. The presentation included |
| | 142 | 5 mins on history of Computer Graphics Lab, 30 mins of Chimera demonstration: basic usage, finding |
| | 143 | H-bonds, morphing, viewing sequences, showing attribute values, building multimers, stereo. Prep time |
| | 144 | 16 hours including updating and rehearsing the presentation, updating and preparing handouts. |
| | 145 | - Elaine Meng, Eric Pettersen |
| | 146 | |
| | 147 | November 8, 2012 |
| | 148 | EFI meeting, San Francisco. SFLD new features. ~6 hours prep, ~15 participants including |
| | 149 | EFI Advisory Committee and NIH representatives. |
| | 150 | - Patsy Babbitt |
| | 151 | |
| | 152 | November 15, 2012 |
| | 153 | Demonstration of Chimera for viewing, segmenting and measuring microscopy data given at the Northern California Society for Microscopy meeting at UCSF. [http://www.cgl.ucsf.edu/chimera/data/ncsm-nov2012/microscopy.html Slides]. Walk through of segmenting and measuring termite gut bacteria. Audience of 50. Preparation time 20 hours. Hosted by Larry Ackerman and Steven Samuelsson. |
| | 154 | - Tom Goddard |
| | 155 | |
| | 156 | December 2, 2012 |
| | 157 | Lunch talk to faculty, Department of Bioengineering and Therapeutic Sciences, UCSF. The SFLD and |
| | 158 | enzyme functional annotation. 8 hours prep, 8 attendees. |
| | 159 | - Patsy Babbitt |
| | 160 | |
| | 161 | December 5, 2012 |
| | 162 | Gave 3 hour hands-on Chimera tutorial on map display and analysis at UC Berkeley. Covered basic molecular display, |
| | 163 | segmenting and fitting single particle maps, and extracting regions from termite gut FIBSEM data. |
| | 164 | 12 participants (Auer, Downing, Nogales, Berger labs). 8 hours preparation. Organized by Danielle Jorgens. |
| | 165 | - Tom Goddard |
| | 166 | |
| | 167 | December 13, 2012 |
| | 168 | Gave 3 hour hands-on tutorial for Cytoscape at the 2012 Cytoscape retreat (Gladstone Institutes, UCSF). 60 participants, 8 hours preparation. |
| | 169 | - Scooter Morris |
| | 170 | |
| | 171 | December 13, 2012 |
| | 172 | Cytoscape retreat (Gladstone Institutes, UCSF). Presentation on protein similarity networks and dissemination using the SFLD. |
| | 173 | 8 hours prep time, 60 attendees. |
| | 174 | - Patsy Babbitt |
| | 175 | |
| | 176 | December 19, 2012 |
| | 177 | Gave 3 hour hands-on advanced Chimera tutorial on map segmentation at UC Berkeley. |
| | 178 | Covered surface masking, watershed segmentation, and zones around markers and atoms |
| | 179 | using HIV virus, microtubule and T-cell maps. 10 participants. 8 hours preparation. |
| | 180 | Organized by Danielle Jorgens. |
| | 181 | - Tom Goddard |
| | 182 | |
| | 183 | January 7, 2013 |
| | 184 | Enzyme Mechanisms Meeting Workshop, San Diego, CA. Introduction to similarity networks and the SFLD. |
| | 185 | 12 hours prep time, 50 attendees. |
| | 186 | - Patsy Babbitt |
| | 187 | |
| | 188 | January 21, 2013 |
| | 189 | iPQB graduate program (UCSF) pizza talk including an introduction to the SFLD. |
| | 190 | 3 hours prep, ~30 attendees. |
| | 191 | - Patsy Babbitt |
| | 192 | |
| | 193 | January 29, 2013 |
| | 194 | Biophysics seminar at UT Southwestern Medical School, Dallas, TX. Similarity networks and the SFLD. |
| | 195 | 9 hours prep, 45 attendees. |
| | 196 | - Patsy Babbitt |
| | 197 | |
| | 198 | January 31, 2013 |
| | 199 | Gave a plenary presentation on Visualization Challenges in Network Biology at the HCI (Human-Computer Interaction) Korea annual conference. 2,000 participants, 20 hours preparation. |
| | 200 | - Scooter Morris |
| | 201 | |
| | 202 | February 7, 2013 |
| | 203 | [http://www.sbgrid.org/news/article/id=363 Webinar] for [http://www.sbgrid.org/Structural Biology Grid] demonstrating Chimera molecular assembly |
| | 204 | and electron microscopy tools. Built alpha crystallin model. 30 minute demo. 6 hours preparation. |
| | 205 | 35 participants. Organized by Michelle Ottaviano, Jason Key, and Piotr Sliz. |
| | 206 | - Tom Goddard |
| | 207 | |
| | 208 | February 8, 2013 |
| | 209 | Demonstrated Chimera visualization, satellite tobacco mosaic virus, differential gear nano-machine, x-ray density maps, |
| | 210 | to two groups of candidate graduate students for the UCSF iPQB program (biophysics and bioinformatics). |
| | 211 | 8 participants. 30 minutes each demo. 2 hours preparation. Organized by Rebecca Brown. |
| | 212 | - Tom Goddard |
| | 213 | |
| | 214 | February 15, 2013 |
| | 215 | Demonstrated Chimera visualization, white blood cell 3d motion and HIV reverse transcriptase inhibitor binding, |
| | 216 | to two groups of candidate graduate students for the UCSF iPQB program (biophysics and bioinformatics). |
| | 217 | 14 participants. 30 minutes each demo. 4 hours preparation. Organized by Rebecca Brown. |
| | 218 | - Tom Goddard |
| | 219 | |
| | 220 | March 4, 2013 |
| | 221 | Short introduction to the SFLD database, Conference on Predicting Cell Metabolism and Phenotypes, SRI international, Menlo Park, CA. |
| | 222 | 3 hours prep time and ~100 participants. |
| | 223 | - Eyal Akiva |
| | 224 | |
| | 225 | March 8, 2013 |
| | 226 | Demonstration showing molecules of life, water, protein, dna, drugs (THC and nevirapine), to 8 students from |
| | 227 | Dewey High School in Oakland using 3-d projection in the visualization vault. 30 minute demo. 6 hours |
| | 228 | preparation. Organized by Veronica Zepeda, UCSF iGEM and Education Coordinator. |
| | 229 | - Tom Goddard |
| | 230 | |
| | 231 | March 19, 2013 |
| | 232 | 1/2 day Chimera tutorial at [http://vizbi.org/2013/ VizBI 2013], the 4th international meeting on Visualizing Biological Data (Broad Institute, Cambridge, MA). Anticipate about 15 participants. |
| | 233 | - Scooter Morris |
| | 234 | |
| | 235 | March 20, 2013 |
| | 236 | Invited talk on Network Visualization at [http://vizbi.org/2013/ VizBI 2013]. Anticipate an audience of about 200. |
| | 237 | - Scooter Morris |
| | 238 | |
| | 239 | April 5, 2013 |
| | 240 | Presentation on "Protein function curation: linking sequence & chemical reaction spaces in the SFLD" at [http://www.ebi.ac.uk/biocuration2013/content/meeting-schedule Biocuration 2013], the conference of the International Society for Biocuration (Cambridge, England). Anticipate 6 hours preparation, 100 attendees. |
| | 241 | - Gemma Holliday |
| | 242 | |
| | 243 | April 21, 2013 |
| | 244 | ASBMB (American Society for Biochemistry and Molecular Biology) annual meeting, Boston, MA. |
| | 245 | Introduction to networks and downloadable information available from the SFLD, as part of the |
| | 246 | EFI workshop "New strategies for function assignment." Anticipate 8 hours prep time, 75 attendees. |
| | 247 | - Patsy Babbitt |
| | 248 | |
| | 249 | May 29, 2013 |
| | 250 | EFI 3-year review. SFLD vision for the next 5 years. Anticipate 8 hours prep time, 15 participants. |
| | 251 | - Patsy Babbitt |