--------------------------------------------------------------------------- 2009/2010 report --------------------------------------------------------------------------- May 21, 2009 Talk to ten San Francisco high school teachers, part of the Current Science Seminar Series organized by the UCSF Science and Health Education Partnership. (http://biochemistry.ucsf.edu/programs/sep/) Showed stereo visualization and manipulation of man-made molecular machines and viruses. Made paper virus models. Held in RBVI visualization room. 12 hours preparation time. - Tom Goddard June 11, 2009 Second talk to high school teachers in the Current Science Seminar Series given by the UCSF Science and Health Education Partnership. Showed stereo visualization and manipulation of man-made molecular machines and viruses. Made paper virus models. Held in RBVI visualization room. 3 hours preparation time. - Tom Goddard June 24, 2009 Virus visualization demonstration for a dozen science summer school students ages 9 to 12 (http://www.celsiusandbeyond.com/). Showed stereo visualization, space navigator, phantom force feedback, protein and rna structure and virus paper models. Held in RBVI visualization room. 12 hours preparation time. - Tom Goddard July 14, 2009 Molecular visualization demonstration for ~30 kids from the COSMOS summer school program at U.C. Davis (http://www.ucop.edu/cosmos/). Showed stereo visualization, virus structures, protein, dna, and protein docked with dna. - Scooter Morris July 15, 2009 Virus visualization demonstration for 5 science summer school students ages 9 to 12 (http://www.celsiusandbeyond.com/). Showed stereo visualization, space navigator, phantom force feedback, protein and rna structure and virus paper models. Held in RBVI visualization room. 4 hours preparation time. - Tom Goddard August 19, 2009 Chimera talk and demonstration, Molecular Visualization symposium (COMP division, see http://oasys2.confex.com/acs/238nm/techprogram/S32080.HTM ) at the 238th American Chemical Society National Meeting (Washington, DC). Prep time by Elaine 60 hours including deciding what features to show and finding an appropriate biological system with which to show them, reading papers about the biological system, generating or finding associated data files, testing the features thoroughly, and iteratively adjusting presentation order and scope. - Tom Ferrin, Elaine Meng September 1, 2009 Demonstration for NIH visitors from Clinical and Translation Science Awards (CTSA). Showed HIV spike tomography, T-cell tomography, clathrin cage animation, cytoscape. Held in RBVI visualization room. 6 hours preparation time. - Tom Goddard, Scooter Morris, Tom Ferrin September 22, 2009 Gave a talk and training session at the EMBO European School of Genetic Medicine course entitled "Embo Practical course on Networks in Biology analysis, modeling and reverse engineering." My talk was an introduction to the "Analysis & Visualisation of biological networks" and the practical covered uses of Cytoscape. There were 60 students from throughout Europe, and 6 faculty in attendance. Bologna, Italy. Prep time for talk: 16 hours, for lab: 8 hours. - Scooter Morris September 28, 2009 Gave an informal seminar at Institute Pasteur for 10 members of the Systems Biology Group on uses of Cytoscape for phylogenetic analysis and cheminformatics. - Scooter Morris September 30, 2009 45-minute Chimera demonstration to ~20 students in UCSF BP204A, "Macromolecular Interactions" class. Included basic usage, morphing, viewing sequences, showing attribute values, building multimers. Prep time 60 hours including looking up information on the history of molecular graphics, working through exercises from the previous year, deciding what structures and features to show and in what order, generating or finding associated data files, testing the features thoroughly, and practicing the presentation. - Elaine Meng, Eric Pettersen October 20, 2009 EMBO practical course: "The combination of electron microscopy and x-ray crystallography for the structure determination of large biological complexes" (http://cwp.embo.org/pc09-18/). One day (7 hours) of hands-on Chimera training during 5 day workshop. 20 students. Grenoble, France. 60 hours preparing materials (http://www.cgl.ucsf.edu/chimera/tutorials/emfit09/emfit.html). - Tom Goddard October 23, 2009 Gave a 3 hour training session to the UCSF BMI206 class (14 Graduate Students) on Cytoscape and structureViz. Prep time: 12 hours. Tutorials are available on-line at http://opentutorials.rbvi.ucsf.edu/ - Scooter Morris December 1, 2009 Demonstrations for three Galileo High School student groups, part of SEP SMART team program organized by Sabine Jeske (http://biochemistry.ucsf.edu/programs/sep/school-programs-smart-teams.html). Presentations covered their proteins: HIV Rev, capase-3, and strictosidine synthase. Included protein analysis, EM data, stereo viewing, space navigator, plastic and paper models. Three groups of ~10 students each in RBVI viz vault. 15 hours preparation and execution. - Tom Goddard December 10, 2009 Demonstrations for two Lincoln High School student groups, part of SEP SMART team program organized by Sabine Jeske (http://biochemistry.ucsf.edu/programs/sep/school-programs-smart-teams.html). Presentations covered their proteins: P-glycoprotein and HIV protease. Also included stereo visualization of nano-gears, ice, water, and lipid bilayers, space navigator and plastic models. Three groups of ~10 students each in RBVI viz vault. 12 hours preparation and execution. - Tom Goddard December 2009 Chimera and Cytoscape used to create image for RBVI holiday card: some of the nuclear pore complex proteins arranged into a Christmas tree, RBVI logo as star, phylogenetic tree as white fronds along the "ground." Estimated 24 person-hours of work. - YZ (Zheng Yang) , Elaine Meng, Conrad Huang, Scooter Morris December 11, 2009 Chimera Release Party and RBVI Open House (2-5 pm in Genentech Hall N453, UCSF Mission Bay) for local researchers and students to meet the Chimera developers, see demonstrations and discuss features, tour the RBVI facilities, and share refreshments. Estimated 80 attendees, 3 hours for the event, 24 person-hours preparation, publicity, and cleanup. - Chimera team January 26, 2010 Remote training using desktop sharing (vnc/skype) for using the Segger segmentation tool to separate bacteria seen in termite gut by focused-ion-beam scanning-EM. Two hours of training for Bernhard Knierim and Monica at Lawrence Berkeley Lab. Four hours preparation time. - Tom Goddard February 1, 2010 All day Cytoscape training for Cell Signaling Technologies in Salem, Mass. 20 Participants including Sr. Scientists, CEO, Marketing personnel, and developers. Preparation time ~20 hours. - Scooter Morris February 11, 2010 Talk at Scripps Research Institute Automated Molecular Imaging (AMI) Forum (http://ami.scripps.edu/forum/) Demonstrated Segger segmentation and fitting capabilities (40 min + 20 min questions) to 35 EM (single-particle and tomography) researchers. Preparation time ~20 hours. - Tom Goddard February 21-23, 2010 Exhibit booth at Biophysical Society Meeting in San Francisco, organized by Scooter Morris of RBVI. Three days, ~24 demonstrations/talks, ~4 NCRR resource centers. - Scooter Morris, Elaine Meng, Eric Pettersen, Zheng Yang, Tom Goddard February 25-26, 2010 Molecular Animation workshop sponsored by RBVI and NCMI. Two days, ~25 participants, 14 talks. Preparation time ~150 person-hours. Hosted by and planned by Tom Ferrin and Scooter Morris from RBVI and Wah Chiu from NCMI. Two talks given by RBVI. [http://plato.cgl.ucsf.edu/trac/Workshops/login/wiki/AnimationWorkshop] - Tom Ferrin, Scooter Morris, Tom Goddard, Zheng Yang March 11-13, 2010 Poster on HIV spike visualization presented at the 5th International Conference on Structural Analysis of Supramolecular Assemblies by Hybrid Methods in Lake Tahoe (http://www.hybridmethods2010.com/). About 180 researchers primarily using electron microscopy attended. Discussed EM map fitting using Chimera and EMDB map and segmentation file formats with approximately 20 people. Preparation time ~15 hours. - Zheng Yang, Tom Goddard March 16, 2010 (entry added in 2011) 20 minute SFLD & cytoscape demo, followed by 10 minute Q & A, showing basic functionality of the SFLD and cytoscape (with sequence similarity networks). Audience: ~20 EFI investigators and other staff. 15 hours preparation. - Shoshana Brown March 17, 2010 1/2 Day Cytoscape training for Al Burlingame's group. 13 participants. Preparation time: ~10 hours. - Scooter Morris