NTT_DATA_UCSF_NIAID-SEB_Subcontract_2021 Task Order !#2 March 1, 2021 - February 28, 2022 1. General ChimeraX improvements to support NIAID (Eric: 20%) 2. Support the NIH 3D pipeline development, including any changes to ChimeraX to support ongoing development. (Eric: 15%) 3. Improve multi-person VR (Tom: 35%) - Create video tutorials in how to use multi-person VR - Hold VR office hours to train researchers to use VR capabilities - Allow participants to add models from local files during a VR session - Set up VR meeting servers for Africa, Europe, Asia 4. Human Biomolecular Atlas Program (HuBMAP) multiscale visualization (Eric: 30%) * Develop ChimeraX tool to browse and select HuBMAP datasets for loading 5. Enhance ChimeraX’s segmentation capabilities * Investigate increased use of simple ITK to support segmentation (Tom: 15%) * Investigate utilizing web services to support more complex machine learning-based segmentation algorithms (Tom: 15%) * Investigate reading and displaying segmentation format(s) available from imaging databases (tissue microscopy, cancer imaging data, etc.) (Tom: 10%) 6. DICOM (Tom: 25%, Eric: 5%) * Improve ability to visualize and analyze medical images in VR with ChimeraX * Develop browser-style interface to show DICOM dataset contents and associated metadata such as sample characteristics 7. Outreach * Instructional material and tools documentation. (20%) * Detailed instructions for all features shall be provided in a user manual * Written user guides and tutorials shall be available as an HTML page 8. Administration (10%) * Submit monthly written reports of accomplishments