= Attendees =

Scooter, Zach, Eric, Tom Goddard, Greg, Elaine, Tom Ferrin

October 23, 2025

= Agenda =

* Tom, deep mutational scan plots, Clause AI - [https://www.rbvi.ucsf.edu/chimerax/data/group-meeting-oct2025/progress-oct2025.html Slides]
* What to do with unused Cytoscape GPU nodes

= Discussion Notes =

* Hiring new faculty
 - !PharmChem department has started a search for a new computational chemistry professor including AI.
 - Tom Ferrin is on the search committee.
 - Candidates for the new position may also be qualified for the RBVI endowed chair position and may be redirected to it.
 - UC hiring freeze excemption was obtained because the new comp chem position is funded.

* Tom work in progress
 - Discussed boltz structure prediction, deep mutational scan plots, new label/arrow gui.
 - Demonstrated Claude control of ChimeraX, attempting to have it replace fentanyl with carfentanil in opioid receptor.  Did not get far due to Claude "Maximum conversation limit reached" after just 3 prompts.  May be related to new mcp_server from Alexis and Zach that has new methods added that may have filled Claude context window of 200,000 tokens.

= Action Items =