= Attendees =

Selina, Zach, Eric, Elaine, TomG, Greg, TomF

November 16, 2023

= Agenda =

* Elaine journal club, [http://www.cgl.ucsf.edu/home/meng/jclub/slicertms.html SlicerTMS slides]
* Zach gave Kansas University ChimeraX tutorial with Phenix team

= Discussion Notes =

* ChimeraX license management web page
  - Greg working on web page for managing Chimera and ChimeraX licenses including handling revoked or expired licenses.

* Kansas Phenix workshop
  - Zach's ChimeraX cryoEM tutorial at the Phenix workshop at Kansas Univ was well received.
  - Survey of most appreciated talks rated ChimeraX and AlphaFold talks highest.

* Google AlphaFold with ligands
  - Google DeepMind published in Nature new results predicting ligands with proteins and nucleic acids.
  - Ligand prediction out-performed AutoDock Vina on benchmark by a large margin.
  - Ligand is input as SMILES string, individual heavy atoms are "tokens" for neural net input.
  - Code has not been released.  Will it be commercialized?

* Elaine journal club, SlicerTMS
  - Showed fast machine learning prediction of electric field in brain for treating depression.
  - Software is an extension to Slicer 3D.
  - Can be used with visualization of MRI and tractography.
  - Can work with Slicer VR and AR.

* New Mac computers
  - Tom Ferrin ordered new iMac for Elaine and Mac Studio for Tom G.

= Action Items =