id	summary	reporter	owner	description	type	status	priority	milestone	component	version	resolution	keywords	cc	blockedby	blocking	notify_on_close	platform	project
20787	Add alphafold fetch for mutation scores sequences	Tom Goddard	Tom Goddard	"Add a button to the Mutation Scores panel to fetch an AlphaFold database predicted atomic structure for the sequence of opened mutation data.  The main purpose of the ChimeraX mutation capabilities is to color structures using mutation data.  While an experimental structure is often available it helps to include all the disordered loops and N and C terminal portions because mutational scans include those functionally signficant residues.  Using an AlphaFold prediction serves this purpose.

Their may not be an exact sequence match from the AlphaFold database.  In that case open the closest sequence and associate the structure with the mutation data using a sequence alignment."	enhancement	closed	moderate		Structure Analysis		fixed						all	ChimeraX