id	summary	reporter	owner	description	type	status	priority	milestone	component	version	resolution	keywords	cc	blockedby	blocking	notify_on_close	platform	project
17555	Optimize Boltz predictions for large structures	Tom Goddard	Tom Goddard	"Boltz runs out of memory or takes a very long time predicting structures over 1000 residues.  Here are some timings

    https://www.rbvi.ucsf.edu/chimerax/data/boltz-apr2025/boltz_help.html#runtimes

An idea to improve the run time and memory use is to use bfloat16 values instead of float32 both in the model weights and the activations.  Another idea is to use matrix multiplications using bfloat16 operations provided by tensor cores in Nvidia GPUs.  Test these ideas to see if they help."	enhancement	assigned	moderate		Structure Prediction								all	ChimeraX