[Chimera-users] Autodock Vina web service is no longer available

[Elaine Meng]

Hi Minoli Aponso,
The Autodock Vina web service (which was provided by another group, not ours) was discontinued a few months ago and will no longer be available.

To use the local pathway option, you first have to download the Autodock Vina program from <http://vina.scripps.edu/> to your own computer, and then in the Chimera tool, change the location to wherever you put the executable.  

See the Chimera Autodock Vina help page for details:
<http://www.rbvi.ucsf.edu/chimera/docs/ContributedSoftware/vina/vina.html>

If you already did the local installation and running failed, it is not possible for us to know the problem without more details, and you should use menu: Help... Report a Bug after getting the error instead of sending e-mail here.

Even if you are succesful in using a locallly installed Autodock Vina, however, the Chimera tool only allows very little sampling and is not recommended for most research purposes. 

You might ask “well why is this tool in Chimera, then?”  You can see a longer answer in the bottom half of this message:
<http://plato.cgl.ucsf.edu/pipermail/chimera-users/2019-July/015992.html>

If you use Autodock Vina directly (not with Chimera), when it's done you can still open the results in the Chimera ViewDock tool for analysis. Or, you could use some other docking program (DOCK, GOLD, Haddock, etc.) or web server (SwissDock, Webina, etc.) instead.

I hope this helps,
Elaine
-----
Elaine C. Meng, Ph.D.                       
UCSF Chimera(X) team
Department of Pharmaceutical Chemistry
University of California, San Francisco

> On Aug 9, 2020, at 7:11 PM, Malimige Aponso <malimige.aponso at monash.edu> wrote:
> 
> Hi, 
> I've been using chimera (Platform: Windows; Chimera version: 1.12/build 41623) for my research purposes and it has been a great tool. 
> But now I have encountered an issue when providing the executable location. When I select the opal web service, it shows that the website is down. Alternatively, when I select the local pathway for vina.exe, chimera indicates that the 
> running failed. Can I kindly get assistance to resolve this matter as soon as possible? 
> Thank you.
> Kind regards, 
> Minoli Aponso.