[Chimera-users] Mutate by D- res...

[Elaine Meng]

Hi Yasser,
Sorry, mutation with the Rotamers tool (or swapaa command) is only to  
L-amino acids.

Some less convenient alternatives:

- use Build Structure (under Tools... Structure Editing) to build out  
the D- side chain manually.  Note the resulting bond lengths and  
angles are approximate.

- open another structure that contains the D- amino acid, match the  
backbone atoms of the residue you wish to substitute, write out  
coordinates "relative to" the first structure, then manually edit the  
PDB file to substitute that sidechain for the one originally in the  
structure.

I hope this helps,
Elaine
-----
Elaine C. Meng, Ph.D.                          meng at cgl.ucsf.edu
UCSF Computer Graphics Lab and Babbitt Lab
Department of Pharmaceutical Chemistry
University of California, San Francisco
                      http://www.cgl.ucsf.edu/home/meng/index.html




On Jun 27, 2008, at 12:33 PM, Yasser Almeida Hernández wrote:

> Can Chimera mutate by D-residues? If this is possible, how i can do  
> it?
>
> Thanks...
> -- 
> Yasser Almeida Hernández
> Estudiante, 4to Año Bioquímica
> Facultad de Biología
> Universidad de la Habana