<html><head><meta http-equiv="Content-Type" content="text/html; charset=us-ascii"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class="">Hi Jianping,<div class=""><br class=""></div><div class=""> Adding memory to your computer should not break ChimeraX -- that is probably not the problem. Two possible problems are 1) your graphics driver got updated and no longer works -- in that case update your graphics driver, or 2) your ChimeraX settings got corrupted. On Windows the settings are in</div><div class=""><br class=""></div><div class=""><span class="Apple-tab-span" style="white-space:pre"> </span>C:\Users\yourname\AppData\Local\UCSF\ChimeraX\<br class=""><div><br class=""></div><div>Remove or rename that directory and ChimeraX will use default settings and perhaps it will start.</div><div><br class=""></div><div><span class="Apple-tab-span" style="white-space:pre"> </span>Tom</div><div><br class=""><blockquote type="cite" class=""><div class="">On Feb 7, 2021, at 9:06 PM, Jianping Wu <<a href="mailto:wujp0828@163.com" class="">wujp0828@163.com</a>> wrote:</div><br class="Apple-interchange-newline"><div class=""><div style="line-height: 1.7; font-size: 14px; font-family: Arial;" class=""><div style="margin:0;" class="">Hi all,</div><div style="margin:0;" class=""><br class=""></div><div style="margin:0;" class="">I cannot open chimeraX1.1 in my PC after I adding a memory to the computer (Win10 system). All other programs in my PC are not affected. The GUI just did not show up after I click the icon. There was no error message. The wired thing was even after I removed the added memory, I still cannot open it. Re-installation of chimeraX was also not helpful. </div><div style="margin:0;" class="">Can anyone help me with it? </div><div style="margin:0;" class=""><br class=""></div><div style="margin:0;" class="">Thanks a lot!</div><div style="margin:0;" class="">Jianping</div></div>_______________________________________________<br class="">ChimeraX-users mailing list<br class=""><a href="mailto:ChimeraX-users@cgl.ucsf.edu" class="">ChimeraX-users@cgl.ucsf.edu</a><br class="">Manage subscription:<br class="">https://www.rbvi.ucsf.edu/mailman/listinfo/chimerax-users<br class=""></div></blockquote></div><br class=""></div></body></html>