<html xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40"><head><meta http-equiv=Content-Type content="text/html; charset=utf-8"><meta name=Generator content="Microsoft Word 15 (filtered medium)"><style><!--
/* Font Definitions */
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0cm;
margin-bottom:.0001pt;
font-size:12.0pt;
font-family:"Calibri",sans-serif;}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:#0563C1;
text-decoration:underline;}
a:visited, span.MsoHyperlinkFollowed
{mso-style-priority:99;
color:#954F72;
text-decoration:underline;}
span.EmailStyle17
{mso-style-type:personal-compose;
font-family:"Calibri",sans-serif;
color:windowtext;}
span.apple-converted-space
{mso-style-name:apple-converted-space;}
.MsoChpDefault
{mso-style-type:export-only;
font-family:"Calibri",sans-serif;}
@page WordSection1
{size:612.0pt 792.0pt;
margin:72.0pt 72.0pt 72.0pt 72.0pt;}
div.WordSection1
{page:WordSection1;}
--></style></head><body lang=EN-GB link="#0563C1" vlink="#954F72"><div class=WordSection1><p style='margin:0cm;margin-bottom:.0001pt'><span style='color:black'>Dear ChimeraX users,<o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='color:black'><o:p> </o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt'><span style='color:black'>We are in the process of redesigning the ligand pages of PDBe and we would be grateful if you could fill out a short survey to help us understand what information about small molecules / ligands you would find useful. The survey is available at</span><span class=apple-converted-space><span style='color:black'> </span></span><span style='color:black'><a href="https://bit.ly/2FFmHFG"><span style='color:#1155CC'>https://bit.ly/2FFmHFG</span></a>.<o:p></o:p></span></p><p class=MsoNormal style='caret-color: rgb(0, 0, 0);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px'><span style='color:black'> <o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt;caret-color: rgb(0, 0, 0);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px'><span style='color:black'>Recently, we have introduced protein-specific aggregated views on the structural data (<a href="http://pdbe-kb.org/proteins"><span style='color:#1155CC'>pdbe-kb.org/proteins</span></a>) as a part of Protein Data Bank in Europe Knowledge Base (PDBe-KB). We highlight the available information related to structures of specific proteins, including structural and functional annotations, domains, ligand-binding sites and interfaces. In the next step we would like to present a similar aggregated view from a small molecule / ligand perspective.</span><span class=apple-converted-space><span style='color:black'> </span></span><span style='color:black'><o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt;caret-color: rgb(0, 0, 0);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px'><span style='color:black'> <o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt;caret-color: rgb(0, 0, 0);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px'><span style='color:black'>Thank you for your time,<o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt;caret-color: rgb(0, 0, 0);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px'><span style='color:black'>Lukas<o:p></o:p></span></p><p style='margin:0cm;margin-bottom:.0001pt;caret-color: rgb(0, 0, 0);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px'><span style='color:black'> <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;color:black'>--<o:p></o:p></span></p><p class=MsoNormal style='caret-color: rgb(0, 0, 0);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px'><span style='font-size:11.0pt;color:black'>Lukas Pravda, Ph.D.<o:p></o:p></span></p><p class=MsoNormal style='caret-color: rgb(0, 0, 0);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px'><span style='font-size:11.0pt;color:black'>Bioinformatician/Scientific Programmer<o:p></o:p></span></p><p class=MsoNormal style='caret-color: rgb(0, 0, 0);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px'><span style='font-size:11.0pt;color:black'> <o:p></o:p></span></p><p class=MsoNormal style='caret-color: rgb(0, 0, 0);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px'><span style='font-size:11.0pt;color:black'>Protein Data Bank in Europe (PDBe)<o:p></o:p></span></p><p class=MsoNormal style='caret-color: rgb(0, 0, 0);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px'><span style='font-size:11.0pt;color:black'>European Bioinformatics Institute (EMBL-EBI)<o:p></o:p></span></p><p class=MsoNormal style='caret-color: rgb(0, 0, 0);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px'><span style='font-size:11.0pt;color:black'>Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD<o:p></o:p></span></p><p class=MsoNormal style='caret-color: rgb(0, 0, 0);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px'><span style='font-size:11.0pt;color:black'>United Kingdom<o:p></o:p></span></p><p class=MsoNormal style='caret-color: rgb(0, 0, 0);font-variant-caps: normal;orphans: auto;text-align:start;widows: auto;-webkit-text-size-adjust: auto;-webkit-text-stroke-width: 0px;word-spacing:0px'><span style='font-size:11.0pt;color:black'> <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'><o:p> </o:p></span></p></div></body></html>