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<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Dear Chimera developers,</p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">I’m working on a protein complex and I’d like to analyse the SASA and hydrophobicity on the surface.</p>
<p class="MsoNormal">I have worked with Chimera before so I know how to do those basic tasks for a monomeric protein; however, since I have five monomers interacting together I was wondering how to calculate the SASA (and later showing the hydrophobic residues
of the surface) excluding the monomer-monomer interfacial regions.</p>
<p class="MsoNormal">I would also need those values tabulated to show hydrophobicity vs primary sequence but still excluding the monomer-monomer interfaces!
</p>
<p class="MsoNormal">It seems like there is no basic tool to do that (or am I missing something?); is there any procedure I could apply?</p>
<p class="MsoNormal">Unfortunately I can’t code in Python so I’m looking for a solution that involves using the GUI.</p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Thank you,</p>
<p class="MsoNormal">Best regards,</p>
<p class="MsoNormal">Alessandro Strofaldi, PhD</p>
<p class="MsoNormal">University of Bristol</p>
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