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<p class="MsoNormal">Dear Chimera Team,<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">I have a reference protein domain and then a series of PDB files which all contain the same domain. I have programmatically been able to script an alignment of the reference to the same domain in the other files whereby he domain in the
 proteins of interest are isolated using the zone select method. This however leaves me with fragments and often misses some of the domain features of the interest proteins that occur outside of the specified zone.
<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">I am wondering if it is possible to write a python script that selects the area on the protein of interest by selecting the residues in the sequence alignment after MatchMaker is conducted. For instance – protein #0 is my reference protein,
 which is 150 residues long. My protein of interest contains the same domain as the reference, but is 500 residues long. Upon conducting MatchMaker and getting an output sequence alignment, the 150 residues of #0 (the reference) are selected, along with the
 aligned residues in the protein of interest. It is possible to select the residues in the sequence alignment window (as in the picture) but I wish to be able to script it. The selected 150 residues (or so) in the protein of interest are then saved as their
 own trimmed file. I have been able to write a python script for completing the MatchMaker etc, but I am not sure how to achieve the selection of residues in #1 based of the alignment with #0, or if it is even possible.<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">Thanks<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal" style="background:white"><b><span style="font-size:12.0pt;color:#44546A;mso-fareast-language:EN-AU">Zachariah Schuurs</span></b><b><span style="font-size:12.0pt;color:#0070C0;mso-fareast-language:EN-AU"> </span></b><b><span style="color:#0070C0;mso-fareast-language:EN-AU"> </span></b><b><span style="color:#A6A6A6;mso-fareast-language:EN-AU">|
 PhD Candidate </span></b><span style="font-size:12.0pt;color:black;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><b><span style="font-size:12.0pt;color:#44546A;mso-fareast-language:EN-AU">CARP – Cancer & Ageing Research Program</span></b><span style="font-size:12.0pt;font-family:"Candara",sans-serif;color:#44546A;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span style="font-size:10.0pt;color:#1F497D;mso-fareast-language:EN-AU">Institute of Health and Biomedical Innovation</span><span style="font-size:10.0pt;color:#A6A6A6;mso-fareast-language:EN-AU"> <b>|</b> </span><span style="font-size:10.0pt;color:#1F497D;mso-fareast-language:EN-AU">Queensland
 University of Technology</span><span style="font-size:12.0pt;font-family:"Candara",sans-serif;color:black;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span style="font-size:10.0pt;color:#1F497D;mso-fareast-language:EN-AU">Level 6</span><span style="font-size:10.0pt;color:#44546A;mso-fareast-language:EN-AU"> </span><b><span style="font-size:10.0pt;color:#A6A6A6;mso-fareast-language:EN-AU">|</span></b><span style="font-size:10.0pt;color:#44546A;mso-fareast-language:EN-AU"> </span><span style="font-size:10.0pt;color:#1F497D;mso-fareast-language:EN-AU">Translational
 Research Institute</span><span style="font-size:10.0pt;color:#44546A;mso-fareast-language:EN-AU"> </span><b><span style="font-size:10.0pt;color:#A6A6A6;mso-fareast-language:EN-AU">|</span></b><span style="font-size:10.0pt;color:#44546A;mso-fareast-language:EN-AU"> </span><span style="font-size:10.0pt;color:#1F497D;mso-fareast-language:EN-AU">37
 Kent St</span><span style="font-size:10.0pt;color:#44546A;mso-fareast-language:EN-AU"> </span><b><span style="font-size:10.0pt;color:#A6A6A6;mso-fareast-language:EN-AU">|</span></b><span style="font-size:10.0pt;color:#44546A;mso-fareast-language:EN-AU"> </span><span style="font-size:10.0pt;color:#1F497D;mso-fareast-language:EN-AU">Woolloongabba
 QLD 4102</span><span style="font-size:12.0pt;font-family:"Candara",sans-serif;color:black;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><b><span style="font-size:10.0pt;color:#92D050;mso-fareast-language:EN-AU">T: </span></b><span style="font-size:10.0pt;color:#44546A;mso-fareast-language:EN-AU">+61 7 3443 7296</span><span style="font-size:10.0pt;color:#0070C0;mso-fareast-language:EN-AU">  <b> </b></span><b><span style="font-size:10.0pt;color:#A6A6A6;mso-fareast-language:EN-AU">| </span></b><b><span style="font-size:10.0pt;color:#92D050;mso-fareast-language:EN-AU">E:</span></b><span style="font-size:10.0pt;color:#92D050;mso-fareast-language:EN-AU"> </span><u><span style="font-size:10.0pt;color:#0563C1;mso-fareast-language:EN-AU">zachariah.schuurs@hdr.qut.edu.au</span></u><span style="font-size:10.0pt;color:#1F497D;mso-fareast-language:EN-AU"> </span><b><span style="font-size:10.0pt;color:#A6A6A6;mso-fareast-language:EN-AU">| </span></b><b><span style="font-size:10.0pt;color:#92D050;mso-fareast-language:EN-AU">Web</span></b><b><span style="font-size:10.0pt;color:#A6A6A6;mso-fareast-language:EN-AU">: </span></b><span style="mso-fareast-language:EN-AU"><a href="http://www.carp.org.au/"><b><span style="font-size:10.0pt;color:#0563C1">www.carp.org.au</span></b></a></span><span style="font-size:12.0pt;font-family:"Candara",sans-serif;color:black;mso-fareast-language:EN-AU"><o:p></o:p></span></p>
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<p class="MsoNormal"><i><span style="mso-fareast-language:EN-AU"><o:p> </o:p></span></i></p>
<p class="MsoNormal"><i><span style="mso-fareast-language:EN-AU"><o:p> </o:p></span></i></p>
<p class="MsoNormal"><i><span style="mso-fareast-language:EN-AU"><o:p> </o:p></span></i></p>
<p class="MsoNormal"><i><span style="mso-fareast-language:EN-AU"><o:p> </o:p></span></i></p>
<p class="MsoNormal"><i><span style="mso-fareast-language:EN-AU"><o:p> </o:p></span></i></p>
<p class="MsoNormal"><i><span style="mso-fareast-language:EN-AU"><o:p> </o:p></span></i></p>
<p class="MsoNormal"><i><span style="mso-fareast-language:EN-AU">I acknowledge the Turrbal and Yugara, as the First Nations owners of the lands where QUT now stands. I pay respect to their Elders, lores, customs and creation spirits. I recognise that these
 lands have always been places of teaching, research and learning.</span></i><i><span style="font-size:12.0pt;mso-fareast-language:EN-AU"><o:p></o:p></span></i></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-AU"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="color:#7F7F7F;mso-fareast-language:EN-AU">This email and its attachments (if any) contain confidential information intended for use by the addressee and may be privileged. We do not waive any confidentiality, privilege or copyright
 associated with the email or the attachments. If you are not the intended addressee, you must not use, transmit, disclose or copy the email or any attachments. If you receive this email by mistake, please notify the sender immediately and delete the original
 email.<o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
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