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<p>We don't recommend specific hardware configurations. But we can
give some guidelines. Think about the size of the models you want
to investigate. The larger the models, the more memory you'll
need, both for the CPU and for the GPU. A fast CPU is also
helpful. And you should also consider what kind of storage to
get.</p>
<p>Since you want to run Amber, a CPU with lots of cores would be
good. But, for the same money, a CPU with fewer cores is usually
faster, and Chimera benefits from a faster CPU. You could always
get two workstations :-)<br>
</p>
<p>For GPUs, get a high-end consumer GPU. See
<a class="moz-txt-link-freetext" href="http://plato.cgl.ucsf.edu/trac/chimera/wiki/benchmarks">http://plato.cgl.ucsf.edu/trac/chimera/wiki/benchmarks</a> relative
performance of various GPUs. The exception is if you are going to
view the graphics in 3D stereo -- in that case, you'll need a
workstation graphics card, like the AMD Fire/Radeon Pro or a
nVidia Quadro (stay away from the entry level versions), and a
stereo projector -- it's easier to build a VR setup with a
high-end consumer GPU and use ChimeraX. See <a class="moz-txt-link-freetext" href="https://vr.ucsf.edu/">https://vr.ucsf.edu/</a>
for information about VR.<br>
</p>
<p>For storage, NVMe m.2 drives are the fastest. So if you can
afford it, get it. Otherwise get a SSD drive. Make sure your
scratch space is on the NVMe or SSD. You should add a regular
SATA disk drive for keeping results. SATA drives are much larger
and cheaper. Chimera benefits when starting up from the NVMe/SSD,
but not much while it is running. I expect the same would be true
for PyMol. But the other software on your list would benefit a
lot from faster storage.</p>
<p> Good luck, and please submit benchmark results from what you
do get,<br>
</p>
<p> Greg<br>
</p>
<div class="moz-cite-prefix">On 11/11/19 3:35 AM, Mr wrote:<br>
</div>
<blockquote type="cite"
cite="mid:73c4ad96.da9d.16e5a3eedd4.Coremail.tangc2333@163.com">
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<div>HI Developer</div>
<div><br>
</div>
<div><span class="tlid-translation translation" lang="en"><span
title="" class="">I am about to purchase and use the
software of Chimera1.13.1 . I need to configure a
workstation for processing. I have a long-term plan. Do
you have a recommended computer hardware configuration
here?</span><br>
<br>
<span title="" class="">I will also use the following
program in this workstation:</span><br>
<span title="" class="">Software: Discovery studio
(version 2.5); MOE (version 2015); PyMOL (version 2.3);
Amber (version 14); Schrodinger (version 2018-4x64);
RStudio (3.5), etc.;</span><br>
<span title="" class="">Database: Microarry; TCGA; NCBI;
RNA-seq; RCSB PDB; NONCODE, etc.;</span><br>
<br>
<span title="" class="">Which operating system can run
these software perfectly and let them not conflict with
your company's software.</span><br>
<br>
<span title="" class="">Sorry to ask so many questions, I
hope you can reply to me.</span><br>
<br>
<span title="" class="">Thank you!</span></span></div>
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<br>
<br>
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<pre class="moz-quote-pre" wrap="">_______________________________________________
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