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<div>Hello,</div>
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<div>I’m teaching myself to perform molecular modeling and docking using your tutorials. I am trying to prepare a protein for a vHTS and I have run into a snag during the sphere generation tutorial (<a href="http://dock.compbio.ucsf.edu/DOCK_6/tutorials/sphere_generation/generating_spheres.htm">http://dock.compbio.ucsf.edu/DOCK_6/tutorials/sphere_generation/generating_spheres.htm</a>).</div>
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<div style="font-family: Calibri;"><font face="Calibri,sans-serif">In the section where it says,"</font><span style="font-family: Arial, Helvetica, sans-serif; font-size: 18px;">To generate the spheres, simply use the command "</span><span class="SpellE" style="font-family: Arial, Helvetica, sans-serif; font-size: 18px;">sphgen</span><span style="font-family: Arial, Helvetica, sans-serif; font-size: 18px;">"
in the same folder that contains the INSPH and the rec.ms files. The output will be two files: </span><a href="http://dock.compbio.ucsf.edu/DOCK_6/tutorials/sphere_generation/rec.sph" style="color: rgb(0, 0, 0); font-family: Arial, Helvetica, sans-serif; font-size: 18px;"><span class="SpellE">rec.sph</span></a><span style="font-family: Arial, Helvetica, sans-serif; font-size: 18px;">,
which contains the spheres in clusters, and </span><a href="http://dock.compbio.ucsf.edu/DOCK_6/tutorials/sphere_generation/OUTSPH" style="color: rgb(0, 0, 0); font-family: Arial, Helvetica, sans-serif; font-size: 18px;">OUTSPH</a><font face="Arial,Helvetica,sans-serif"><span style="font-size: 18px;">,
which contains general information about the calculation.” </span></font></div>
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<div style="font-family: Calibri;">I am getting an error that says Unrecognized command: “sphgen”. I downloaded the INSPH text file but I have no idea what to do with it. I don’t know what “folder” the tutorial refers to when it says,”use the command ‘sphgen’
in the same folder that contains the INSPH and rec.ms files."</div>
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<div style="font-family: Calibri;">Any help would be greatly appreciated!</div>
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<div style="font-family: Calibri;">Thanks,</div>
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<div style="font-family: Calibri;">Dan</div>
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