<div dir="ltr"><div class="gmail_default" style="font-family:verdana,sans-serif">Hi,</div><div class="gmail_default" style="font-family:verdana,sans-serif"><br></div><div class="gmail_default" style="font-family:verdana,sans-serif">I am using CASTp plugin from Chimera in order to calculate both the volume and surface area of a specific pocket. I noticed that the 'mouth' atoms can be excluded from the visualization, and even the surface area is reported separately for both the pocket and the mouths by CASTp. However, there is only one reported volume. Is that volume considering both the pocket and mouth atoms to make just one general calculation? In addition, where can I find more info about the criteria to define a pocket's mouth?</div><div class="gmail_default" style="font-family:verdana,sans-serif"><br></div><div class="gmail_default" style="font-family:verdana,sans-serif"><span style="font-size:13px">Thanks in advance for your help.</span><br></div><div class="gmail_default" style="font-family:verdana,sans-serif"><div class="gmail_default" style="font-size:13px"><br></div><div class="gmail_default" style="font-size:13px">Best regards,</div></div><div class="gmail_default" style="font-family:verdana,sans-serif"><br></div><div class="gmail_default" style="font-family:verdana,sans-serif"><br></div><div class="gmail_default" style="font-family:verdana,sans-serif"><b>Andrés Felipe Vásquez J., <i>BSc, MSc.</i></b><br></div><div><div dir="ltr"><div><div><font face="verdana, sans-serif">Grupo de Fisiología Molecular</font></div><div><font face="verdana, sans-serif">Subdirección de Investigación Científica y Tecnológica</font></div><div><font face="verdana, sans-serif">Dirección de Investigación en Salud Pública<br>Instituto Nacional de Salud<br>Avenida calle 26 No. 51-20 - Zona 6 CAN</font></div><div><font face="verdana, sans-serif">+57 (1) 2207700 ext. 1419</font></div><div><font face="verdana, sans-serif">Bogotá, D.C., Colombia<span style="font-size:small"> </span></font><br></div></div></div></div>
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