<div dir="ltr"><div><div><div><div>Dear Chimera users!<br>
<br>
<br>
</div>I'm looking for the possible python script which using the Chimera's
source would introduce selected mutations in the defined PDB file and
produce PDB output containing such protein with the selected
substitution residues. It would be also good if rotamers for mutation
residues would be backbone dependent or taken from the existing rotamer
libraries (although its not essence because I can run minimization on
the mutants)<br>
<br>
</div>Previously I've done such tasks with selectivity mutations via Chimera-GUI rotamer plugin but now I'd like to obtain big series of the mutant of studied
protein for further examinations of such mutants by means of molecular
dynamics simulation. <br>
Could someone provide me with such script if it could not be very complicated to make it? <br>
<br>
<br>
</div>Thanks for help,<br>
<br>
</div>James</div>