<p>Hi Elaine,<br></p>
<p>Thanks for the answer for the previous question. I am back with one more :)<br></p>
<p>Is there a way to completely denature a protein in Chimera? The idea is to completely unfold a particular protein (for ex: chemical denaturation GdHCl/Urea or thermal denaturation) to its primary structure. Also can this be modeled in such a way that we can extract thermodynamic parameters from the modeling? I do understand this sounds a lot like a Molecular Dynamics simulation but maybe there is a way in Chimera?<br>
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<p>Thanks again<br></p>
<p>Vamsee</p>