[Chimera-users] Changing DNA sequence
Tom Goddard
goddard at sonic.net
Mon Jul 26 11:21:11 PDT 2021
Hi Gary,
The swapna command lets you change a nucleic acid base, for example, to change residue 18 in chain C from a T to a G use
open 1rsb
swapna G :18.C
Documentation for swapna
https://www.cgl.ucsf.edu/chimera/current/docs/UsersGuide/midas/swapna.html <https://www.cgl.ucsf.edu/chimera/current/docs/UsersGuide/midas/swapna.html>
Tom
> On Jul 26, 2021, at 1:31 AM, <gren at lbl.gov> <gren at lbl.gov> wrote:
>
> Dear Tom
> Thanks for many answers to our previous questions.
>
> I have one more question to our loved Chimera program.
>
> I have a NDA model (PDB), but the sequence is not right. Is there any way to use this DNA model to generate a new model with a right order of sequence? In other word, if is there an automatic/ simple method (by comment lines) to replace the sequence by the correct one in Chimera?
>
> Thanks a lot!!
> Gary
>
>
> Gang (Gary) Ren, PhD
> Lawrence Berkeley National Laboratory
> Molecular Foundry, Room: 2220
> 1 Cyclotron Road, MS 67R2206
> Berkeley CA 94720-8197
> Phone: (510) 495-2375; Fax: (510) 486-7268
> Email: gren at lbl.gov <mailto:gren at lbl.gov>;
> https://rengroup.lbl.gov/ <https://rengroup.lbl.gov/>
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