[Chimera-users] Changing DNA sequence

Tom Goddard goddard at sonic.net
Mon Jul 26 11:21:11 PDT 2021

Hi Gary,

  The swapna command lets you change a nucleic acid base, for example, to change residue 18 in chain C from a T to a G use

	open 1rsb
	swapna G :18.C

Documentation for swapna

	https://www.cgl.ucsf.edu/chimera/current/docs/UsersGuide/midas/swapna.html <https://www.cgl.ucsf.edu/chimera/current/docs/UsersGuide/midas/swapna.html>


> On Jul 26, 2021, at 1:31 AM, <gren at lbl.gov> <gren at lbl.gov> wrote:
> Dear Tom
> Thanks for many answers to our previous questions.
> I have one more  question to our loved Chimera program.
> I have a NDA model (PDB), but the sequence is not right. Is there any way to use this DNA model to generate a new model with a right order of sequence? In other word, if is there an automatic/ simple method (by comment lines) to replace the sequence by the correct one in Chimera?
> Thanks a lot!!
> Gary
> Gang (Gary) Ren, PhD
> Lawrence Berkeley National Laboratory
> Molecular Foundry, Room: 2220
> 1 Cyclotron Road, MS 67R2206
> Berkeley CA 94720-8197
> Phone: (510) 495-2375; Fax: (510) 486-7268
> Email: gren at lbl.gov <mailto:gren at lbl.gov>; 
> https://rengroup.lbl.gov/ <https://rengroup.lbl.gov/>
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