[Chimera-users] substitute single residue

Andrew P. Hinck ahinck at biochem.uthscsa.edu
Thu Jul 30 14:57:28 PDT 2009


Dear all,

I was hoping to make some single amino acid substitutions in the  
context of a protein binding interface.  I've only briefly poked  
around, but so far the only way I see to do this is to delete  
existing atoms/bonds one by one, and then rebuild (the alternate  
amino acid) atom-by-atom/bond-by-bond.  Is there an easier way (like,  
telling the program to substitute an Asp for a Lys, or something akin  
to this)?  Thanks in advance for any suggestions.

Andy Hinck

Andrew P. Hinck, Ph.D.
Professor, Department of Biochemistry, MC 7760
University of Texas Health Science Center at San Antonio
San Antonio, TX 78229-3900
office:  210-567-8780
mobile:  210-725-4438
fax:  210-567-8778
email: hinck at uthscsa.edu
websites: http://hincklab.uthscsa.edu
                   http://nmr.uthscsa.edu

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